Magnetic resonance imaging device and control method thereof
09945921 ยท 2018-04-17
Assignee
- Samsung Electronics Co., Ltd. (Suwon-si, Gyeonggi-Do, KR)
- Korea Advanced Institute Of Science And Technology (Daejeon, KR)
Inventors
Cpc classification
G01R33/543
PHYSICS
G01R33/56383
PHYSICS
G01R33/56509
PHYSICS
International classification
Abstract
An MRI apparatus performs an MRI while moving a patient table and includes a main magnet configured to generate a static magnetic field in a bore; a gradient coil assembly configured to apply a gradient signal to the static magnetic field to generate a magnetic field gradient; an RF coil assembly configured to apply an RF excitation signal and an RF refocusing signal; and a controller configured to control the RF refocusing signal so that a slice to which the RF refocusing signal is to be applied conforms to the slice to which the RF excitation signal has been applied.
Claims
1. A magnetic resonance imaging (MRI) apparatus to perform MRI while moving a patient table, the MRI apparatus comprising: a main magnet configured to generate a static magnetic field in a bore; a gradient coil assembly configured to apply a gradient signal to the static magnetic field to generate a magnetic field gradient; a radio frequency (RF) coil assembly configured to apply an RF excitation signal and an RF refocusing signal; and a controller configured to calculate a center frequency of the RF refocusing signal based on a movement distance of the patient table, and to control the RF coil assembly so that a slice to which the RF refocusing signal is to be applied conforms to the slice to which the RF excitation signal has been applied.
2. The MRI apparatus according to claim 1, wherein the controller is further configured to control the RF coil assembly to apply the RF refocusing signal having the calculated center frequency.
3. The MRI apparatus according to claim 2, wherein the controller is configured to calculate an offset f.sub.offset from a center frequency of the RF excitation signal based on the movement distance of the patient table.
4. The MRI apparatus according to claim 3, wherein the controller is configured to calculate a value shifted by the offset calculated from the center frequency of the RF excitation signal as the center frequency of the RF refocusing signal.
5. The MRI apparatus according to claim 4, wherein the controller is configured to calculate the movement distance of the patient table based on a movement speed of the patient table and a time echo, and the movement distance of the patient table is a movement distance between an application of the RF excitation signal and an application of the RF refocusing signal.
6. The MRI apparatus according to claim 5, wherein the controller is configured to calculate the offset as follows:
f.sub.offset=g.sub.zV(TE)/4, where is a proportional constant, V is the movement speed of the patient table, TE is the time echo, and g.sub.z is a variation of the magnetic field gradient per a unit of distance.
7. The MRI apparatus according to claim 5, wherein the controller is configured to control the gradient coil assembly so that a polarity of the magnetic field gradient generated when the RF excitation signal is applied is opposite to a polarity of the magnetic field gradient generated when the RF refocusing signal is applied.
8. The MRI apparatus according to claim 5, wherein the MRI for multiple slices is performed, and the controller is configured to control the RF coil assembly to apply the RF refocusing signal having the center frequency shifted from the center frequency of the RF excitation signal by the calculated offset to each of the multiple slices.
9. The MRI apparatus according to claim 7, wherein, the controller is configured to control the RF coil assembly to apply the RF excitation signal having the center frequency f.sub.s1 to a first slice and the RF excitation signal having the center frequency f.sub.s1+f.sub.s to a second slice, wherein f.sub.s is an offset according to a slice selection, and to apply the RF refocusing signal having the center frequency f.sub.s1+f.sub.offset to the first slice and the RF refocusing signal having the center frequency f.sub.s1f.sub.s+f.sub.offset to the second slice, wherein f.sub.offset is the offset according to the movement distance of the patient table.
10. The MRI apparatus according to claim 5, wherein the controller is configured to control the RF coil assembly to apply a plurality of RF refocusing signals after application of the RF excitation signal according to a multi echo sequence and to shift the center frequency of each of the plurality of RF refocusing signals according to a movement of the patient table.
11. The MRI apparatus according to claim 9, wherein the controller is configured to adjust the center frequencies of the RF excitation signal and the RF refocusing signal to select an order of the multiple slices.
12. A control method of a magnetic resonance imaging (MRI) apparatus to perform MRI while moving a patient table, the control method comprising: generating, by the MRI apparatus, a static magnetic field in a bore; applying, by the MRI apparatus, a gradient signal to the static magnetic field to generate a first magnetic field gradient; applying, by the MRI apparatus, a radio frequency (RF) excitation signal to select a slice; and applying, by the MRI apparatus, an RF refocusing signal having a center frequency shifted by an offset from a center frequency of the RF excitation signal based on a movement distance of the patient table.
13. The control method according to claim 12, further comprising: calculating the center frequency of the RF refocusing signal based on the movement distance of the patient table.
14. The control method according to claim 13, wherein the calculating the center frequency of the RF refocusing signal comprises: calculating an offset f.sub.offset from the center frequency of the RF excitation signal based on the movement distance of the patient table.
15. The control method according to claim 14, wherein the calculating the center frequency of the RF refocusing signal comprises: calculating a value shifted by the offset calculated from the center frequency of the RF excitation signal as the center frequency of the RF refocusing signal.
16. The control method according to claim 15, wherein the calculating the offset f.sub.offset comprises calculating the movement distance of the patient table based on a movement speed of the patient table and a time echo, wherein the movement distance of the patient table is a movement distance between an application of the RF excitation signal and an application of the RF refocusing signal.
17. The control method according to claim 16, wherein the calculating the offset f.sub.offset further comprises calculating the offset as follows:
f.sub.offset=g.sub.zV(TE)/4, where is a proportional constant, V is the movement speed of the patient table, TE is the time echo, and g.sub.z is a variation of the magnetic field gradient per a unit of distance.
18. The control method according to claim 16, further comprising: generating a second magnetic field gradient having an opposite polarity to the generated first magnetic field gradient when the RF refocusing signal is applied.
19. The control method according to claim 16, further comprising: performing the MRI for multiple slices; and applying the RF refocusing signal having the center frequency shifted from the center frequency of the RF excitation signal by the calculated offset to each of the multiple slices.
20. The control method according to claim 18, further comprising: applying the RF excitation signal having the center frequency f.sub.s1 to a first slice and the RF excitation signal having the center frequency f.sub.s1+f.sub.s to a second slice; and applying the RF refocusing signal having the center frequency f.sub.s1+f.sub.offset to the first slice and the RF refocusing signal having the center frequency f.sub.s1f.sub.s+f.sub.offset to the second slice, wherein f.sub.s is the offset according to a slice selection, and f.sub.offset is the offset according to the movement distance of the patient table.
21. The control method according to claim 16, further comprising: applying a plurality of RF refocusing signals; and shifting the center frequency of each of the plurality of RF refocusing signals according to a movement of the patient table.
22. A magnetic resonance imaging (MRI) apparatus comprising: a main magnet configured to generate a static magnetic field in a bore of an MRI scanner; a gradient coil assembly configured to form a magnetic field gradient in the bore; a radio frequency (RF) coil assembly configured to apply an RF excitation signal to a first slice at a first spatial position in the bore and to apply an RF refocusing signal after a time delay; and a processor programmed to control the RF coil assembly so that the RF refocusing signal is applied to a same first slice positioned at a second spatial position in the bore, which differs from the first spatial position according to a movement distance of a patient table in the bore.
23. The MRI apparatus according to claim 22, wherein the processor is programmed to determine a center frequency of the RF refocusing signal to be offset from a center frequency of the RF excitation signal based on the movement distance of the patient table between an application of the RF excitation signal and an application of the RF refocusing signal, and control the RF coil assembly to apply the RF refocusing signal having the offset center frequency.
24. The MRI apparatus according to claim 23, wherein the processor is programmed to determine the offset as being directly proportional to a product of a speed V of the patient table, the time delay (TE/2), and a variation of a value of a Z-axis magnetic field gradient g.sub.z per a unit of distance and inversely proportional to 2.
25. The MRI apparatus according to claim 22, wherein the processor is programmed to control the gradient coil assembly to reverse a direction of a Z-axis magnetic field gradient when applying the RF refocusing signal.
Description
BRIEF DESCRIPTION OF THE DRAWINGS
(1) The above and/or other aspects will become more apparent by describing certain exemplary embodiments, with reference to the accompanying drawings, in which:
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DETAILED DESCRIPTION
(20) Certain exemplary embodiments are described in greater detail below with reference to the accompanying drawings.
(21) In the following description, the same drawing reference numerals are used for the same elements even in different drawings. The matters defined in the description, such as detailed construction and elements, are provided to assist in a comprehensive understanding of exemplary embodiments. Thus, it is apparent that exemplary embodiments can be carried out without those specifically defined matters. Also, well-known functions or constructions are not described in detail since they would obscure exemplary embodiments with unnecessary detail.
(22)
(23) Referring to
(24) The magnet assembly 150 includes a main magnet 151 to generate a static magnetic field, a gradient coil assembly 152 to apply a gradient to the static magnetic field to generate a gradient field, and a radio frequency (RF) coil assembly 153 to apply an RF pulse to an object to excite atomic nuclei and to receive an echo signal from the atomic nuclei.
(25) The MRI apparatus 100 further includes a patient table 101 to transfer the object into an inner space, i.e., a bore, of the magnet assembly 150. The controller 120 includes a magnet assembly controller 121 to control operation of the magnet assembly 150 and a table controller 122 to control movement of the patient table 101. The magnet assembly controller and the table controller 122 may be embodied using one processor or different processors.
(26) The magnet assembly controller 121 controls intensity and direction of the static magnetic field generated by the main magnet 151. In addition, the magnet assembly controller 121 generates a pulse sequence suitable for a diagnostic region or diagnostic purpose of the object and controls the gradient coil assembly 152 and the RF coil assembly 153 according to the pulse sequence.
(27) The MRI apparatus 100 further includes a static magnetic field controller 170 to apply a static magnetic field current for static magnetic field generation to the main magnet 151, a gradient controller 130 to apply a gradient current for gradient field generation to the gradient coil assembly 152, and an RF transmitter 140 to apply an RF current for RF generation to the RF coil assembly 153.
(28) The magnet assembly controller 121 may control the main magnet 151, the gradient coil assembly 152, and the RF coil assembly 153 through the static magnetic field controller 170, the gradient controller 130, and the RF transmitter 140 to control the static magnetic field generated in the bore, the gradient field, and the RF signal applied to the atomic nuclei.
(29) The RF coil assembly 153 is connected to the image processor 160. The image processor 160 includes a data receiver 161 to receive data regarding an MR signal generated from the atomic nuclei, a data storage unit 162 to store data received from the data receiver 161, and a data processor 163 to process the stored data to generate a magnetic resonance image.
(30) The data receiver 161 may include a preamplifier to amplify an MR signal received by the RF coil assembly 153, a phase detector to receive the MR signal from the preamplifier to perform phase detection, and an analog/digital (A/D) converter to convert an analog signal acquired through phase detection into a digital signal. The data receiver 161 transmits a digitized MR signal to the data storage unit 162.
(31) The data storage unit 162 has a data space constituting a two-dimensional (2D) Fourier space. When storage of all scanned data is completed, the data processor 163 performs 2D inverse Fourier transform on data in the 2D Fourier space to reconfigure an image of the object.
(32) The MRI apparatus 100 may include a user interface 110 which may receive a control command regarding operations of the MRI apparatus 100 from a user through an operating console 111. Particularly, upon receipt of a command regarding a scan sequence to be applied to scan the object from the user, the magnet assembly controller 121 may design a pulse sequence suitable for the scan sequence.
(33) A display 112 may display various kinds of information regarding control of the MRI apparatus 100 and an image generated by the image processor 160 so that the user diagnoses a health state of the object.
(34)
(35) Referring to
(36) The main magnet 151, the gradient coil assembly 152, and the RF coil assembly 153 are mounted in the magnet assembly 150.
(37) The main magnet 151 includes a coil to generate a static magnetic field in the bore, which is referred as a main magnet. The main magnet may be embodied using a superconductive magnet. In this case, the main magnet 151 includes a superconductive coil.
(38) The main magnet 151 may be configured so that a coil is wound around the bore. When current from the static magnetic field controller 170 is applied to the main magnet 151, a static magnetic field is generated in the bore. Generally, the direction of the static magnetic field is parallel to the longitudinal axis of the magnet assembly 150.
(39) When the static magnetic field is generated in the bore, atomic nuclei of atoms, especially hydrogen atoms, constituting the object 50 are arranged in the direction of the static magnetic field and perform precession about the direction of the static magnetic field. Precession speed of the atomic nuclei may be indicated by precession frequency. The precession frequency is referred to as a Larmor frequency, which is represented by the following equation 1.
=B.sub.0[Equation 1]
where, is a Larmor frequency,
is a proportional constant, and
B.sub.0 is intensity of an external magnetic field.
(40) The proportional constant is different for each kind of atomic nuclei. A unit of the intensity of the external magnetic field is tesla (T) or gauss (G). A unit of the precession frequency is Hz.
(41) For example, a hydrogen proton has a precession frequency of 42.58 MHz in an external magnetic field of 1 T. Since hydrogen constitutes majority of the atoms constituting the human body, the MRI apparatus mainly obtains an MR signal using precession of hydrogen protons.
(42) As shown in
(43) When the longitudinal axis of the object 50 is parallel to the direction of the static magnetic field, a tomographic image for a cross section of the object 50 may be obtained. A slice having a predetermined thickness may be selected to obtain the tomographic image.
(44) Gradient fields in the X, Y, and Z axes may be needed to obtain three-dimensional (3D) space information regarding an MR signal. For example, the gradient coil assembly 152 includes three pairs of gradient coils corresponding to the X, Y, and Z axes.
(45) As shown in
(46) The axis gradient coils 152z are used in slice selection, the Y-axis gradient coils 152y are used in phase encoding, and X-axis gradient coils 152x are used in frequency encoding.
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(48) When direct currents having opposite poles flow in two Z-axis gradient coils 152z in opposite directions, a magnetic field is changed in Z-axis direction to generate a gradient field.
(49) When current flows in the Z-axis gradient coils 152z for a predetermined time to generate a gradient field, a resonance frequency is greatly or slightly changed according to the magnitude of the gradient field. When a high frequency corresponding to a specific position is generated by the RF coil assembly 153, only a proton of a section corresponding to the specific position resonates. For example, the axis gradient coils 152z are used in slice selection. The greater the Z-axis magnetic field gradient is, the smaller thickness of the selected slice is.
(50) When a slice is selected through the gradient field generated by the Z-axis gradient coils 152z, spins constituting the slice have the same frequency and phase. For this reason, the spins may not be distinguished from each other.
(51) At this time, when a gradient field is generated by the Y-axis gradient coils 152y in the Y-axis direction, the gradient field causes phase shift so that rows of the slice have different phases.
(52) That is, when the Y-axis gradient field is generated, the phase of the spins of the row to which the large gradient field is applied is changed into high frequency and the phase of the spins of the row to which the small gradient field is applied is changed into low frequency. When the Y-axis gradient field disappears, the respective rows of the selected slice have different phases through phase shift. For example, the spins may be distinguished from each other. In this way, the gradient field generated by the Y-axis gradient coils 152y is used in phase encoding.
(53) The slice is selected through the gradient field generated by the Z-axis gradient coils 152z and the rows constituting the slice selected through the gradient field generated by the Y-axis gradient coils 152y are distinguished from each other as different phases. However, spins constituting the rows have the same frequency and phase. For this reason, the spins may not be distinguished from each other.
(54) At this time, when a gradient field is generated by the X-axis gradient coils 152x in the X-axis direction, the X-axis gradient field enables the spins constituting the respective rows to have different frequencies so that the spins are distinguished from each other. In this way, the gradient field generated by the X-axis gradient coils 152x is used in frequency encoding.
(55) As described above, the gradient fields generated by the Z, Y, and X-axis gradient coils encode spatial position of the respective spins through slice selection, phase encoding, and frequency encoding.
(56) The gradient coil assembly 152 is connected to the gradient controller 130. The gradient controller 130 applies a gradient pulse, i.e., a current pulse, to the gradient coil assembly 152 according to a control signal received from the magnet assembly controller 121 to generate a gradient field. For example, the gradient controller 130 may be a gradient power source. The gradient controller 130 may include three drive circuits corresponding to the three gradient coil pairs 152x, 152y, and 152z constituting the gradient coil assembly 152.
(57) As described above, atomic nuclei arranged by an external static magnetic field perform precession at a Larmor frequency. The magnetization vector sum of several atomic nuclei may be represented by single net magnetization M.
(58) A Z-axis component of the net magnetization cannot be measured, and only traverse magnetization M.sub.xy may be detected. Consequently, the net magnetization may be present on an XY plane to obtain an MR signal. To excite atomic nuclei, an RF pulse tuned to a Larmor frequency of atomic nuclei may be applied to a static magnetic field.
(59) The RF coil assembly 153 includes a transmit coil to transmit an RF pulse and a receipt coil to receive an electromagnetic wave emitted from the excited atomic nuclei, i.e., an MR signal. Alternatively, the RF coil assembly 153 may include a combined transmit and receipt coil, instead of separate transmit and receipt coils.
(60) The RF coil assembly 153 is connected to the RF transmitter 140. The RF transmitter 140 applies a high-frequency signal to the RF coil assembly 153 according to a control signal received from the magnet assembly controller 121 so that the RF coil assembly 153 transmits an RF pulse into the magnet assembly 150.
(61) The RF transmitter 140 may include a modulation circuit to modulate a high-frequency signal into a pulse signal and an RF power amplifier to amplify the pulse signal.
(62) A spin echo pulse sequence is mainly used to obtain an MR signal from atomic nuclei. The spin echo pulse sequence will hereinafter be described in detail.
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(64) When the RF coil assembly 153 applies an RF pulse, an RF pulse to excite atomic nuclei (hereinafter, referred to as an RF excitation signal) is first applied. When the RF excitation signal is applied, dephasing is caused due to inhomogeneity of a magnetic field or interaction between spins. As a result, abruptly reduced free induction decay (FID) signal is generated and an RF refocusing signal for recollection of dephased spins is applied to obtain a stable signal. Therefore, the FID signal is recollected to generate a stable echo signal, i.e., an MR signal. This is referred to as a spin echo pulse sequence. Time taken until an MR signal is generated after application of the RF excitation signal is referred to as time echo (TE).
(65) On the assumption that time when the RF refocusing signal is applied after application of the RF excitation signal is t, an MR signal is generated when the time t elapses after application of the RF refocusing signal. Consequently, TE=2t.
(66) To what extent a proton has been flipped may be indicated by an angle moved from an axis at which the proton had been located before flip. A 90 RF or a 180 RF appears depending upon a flip degree. In the spin echo pulse sequence, the RF excitation signal is referred to as a 90 RF pulse or signal and the RF refocusing signal is referred to as a 180 RF pulse or signal.
(67) Referring to
(68) The MRI apparatus 100 performs MRI using CMT technique. As distance from the isocenter of the magnetic field generated in the bore is increased, uniformity of the magnetic field is reduced. For this reason, MR data are acquired at a position nearest the isocenter to minimize distortion of an image. The isocenter is the center of the magnetic field generated in the bore where the magnitudes of the X-axis magnetic field gradient Gx, the Y-axis magnetic field gradient Gy, and the Z-axis magnetic field gradient Gz are 0.
(69) In the CMT technique, the table is continuously moved during MRI so that a portion of an object to be imaged is located on the isocenter. When the CMT technique is applied, a uniform image may be obtained without acquisition of addition data, such as shimming, or correction of the acquired data.
(70)
(71) As shown in
(72) An RF refocusing signal is applied after the lapse of TE/2. At this time, when an RF refocusing signal having the same frequency as the RF excitation signal is applied, a slice selected by the RF excitation signal RF excitation signal and a slice selected by the RF refocusing signal may not conform to each other as shown in
(73) This is because, when the patient table 101 is moved, the slice selected by the RF excitation signal is also moved, as described in greater detail below with reference to
(74)
(75) Referring to
(76) In
(77) As shown in
(78) Since the MRI apparatus 100 performs imaging while moving the patient table 101, the patient table 101 is moved until the RF refocusing signal is applied after application of the RF excitation signal. As a result, the slice 300 initially selected by the RF excitation signal is no more located between z/2 and z/2.
(79) As shown in
(80) When an RF refocusing signal having the same frequency as the RF excitation signal is applied without considering the movement of the patient table 101, a slice region selected by the RF refocusing signal is between z/2 and z/2.
(81) A commonly selected region between the slice selected by the RF excitation signal and the slice selected by the RF refocusing signal is between z.sub.sz/2 and z/2. An echo signal is generated at the commonly selected region. Since the original slice region, from which the MR signal is to be acquired, is between z.sub.sz/2 and z.sub.s+z/2 at the time of application of the RF refocusing signal, an echo signal for a slice having a smaller thickness than the intended slice may be obtained. As a result, a signal to noise ratio (SNR) of an image signal may be reduced.
(82) When the movement speed of the patient table 101 is fast, no commonly selected region may be provided between the slice region selected by the RF excitation signal and the slice region selected by the RF refocusing signal. In this case, an MR signal for the intended slice may not be obtained.
(83) For example, the MRI apparatus 100 of an exemplary embodiment applies an RF refocusing signal considering movement of the patient table 101.
(84)
(85) As shown in
(86) An RF refocusing signal is applied after the lapse of TE/2. As described above, the slice selected by the RF excitation signal is also moved when the patient table 101 is moved. As shown in
(87) Since refocusing RF selects the slice selected by the RF excitation signal, the slice selected by the RF refocusing signal and the slice selected by the RF excitation signal conform to each other, thereby preventing reduction of a SNR due to inconformity between the slices.
(88)
(89) Referring to
(90) That is, the RF coil assembly 153 may apply an RF refocusing signal having a center frequency shifted to f.sub.1. The magnet assembly controller 121 calculates the center frequency of the RF refocusing signal based on the movement speed of the patient table 101.
(91) The center frequency of the RF is the center frequency of the RF applied by the RF coil assembly 153, which corresponds to a resonance frequency of atomic nuclei present at the center of a slice to be selected. For example, the center frequency of the RF is different in meaning from the center frequency of the magnetic field generated in the bore, i.e., the frequency fc on the isocenter.
(92) The relationship between the resonance frequency f and the magnitude B of an external magnetic field may be derived from Equation 1 as follows:
f=B/2[Equation 2]
(93) Equation 3 regarding a variation of the resonance frequency and a variation of the magnetic field may be derived from Equation 2 as follows:
f=B/2[Equation 3]
(94) On the assumption that a variation of the Z-axis magnetic field gradient per unit of distance is g.sub.z, Equation 3 may be represented by Equation 4 as follows:
f=g.sub.zd/2,[Equation 4]
(95) where d is a movement distance of the table on the Z axis.
(96) When the patient table 101 is moved at a uniform speed Vm/s, the movement distance for the patient table 101 is equal to V(TE/2) until the RF refocusing signal is applied after application of the RF excitation signal. Here, TE is a time echo.
(97) The center frequency offset f.sub.offset for the RF refocusing signal may be represented by Equation 5 as follows:
f.sub.offset=f=g.sub.zV(TE)/4[Equation 5]
(98) The magnet assembly controller 121 calculates offset of the center frequency according to Equation 5 and calculates the frequency shifted by the offset calculated from the center frequency of the RF excitation signal as the center frequency of the RF refocusing signal. The magnet assembly controller 121 controls the RF coil assembly 153 to apply the RF refocusing signal according to the shifted center frequency. The bandwidth of the RF refocusing signal may be equal to that of the RF excitation signal.
(99) Referring back to
(100)
(101) The MRI apparatus 100 may obtain magnetic resonance images for multiple slices. For example, multiple slices may be simultaneously scanned.
(102) As shown in
(103) As shown in
(104) In order to achieve conformity between the slice selected by the RF excitation signal and a slice to be selected by an RF refocusing signal for each slice, the RF refocusing signal for the first slice has a center frequency shifted from f.sub.s1 by f.sub.offset as calculated above and the RF refocusing signal for the second slice has a center frequency shifted from f.sub.s2 by f.sub.offset.
(105) In
(106) In
(107) When the MR signals for the multiple slices are acquired sequentially or in the interleaving fashion, a time interval is present between acquisition of an MR signal for the previous slice and acquisition of an MR signal for the next slice and the patient table 101 is moved for the time interval. For example, the offset of the center frequency based on the movement distance of the patient table 101 may be calculated as described above and the calculate offset may be additionally applied whenever advance to the next slice is performed. The previous slice and the next slice are based on the acquisition order of MR signals, not physical positions. The center frequencies of the RF excitation signal and the RF refocusing signal may be adjusted to select the acquisition order of multiple slices.
(108) Specifically, movement of the patient table 101 is also considered between application of the RF refocusing signal to the previous slice and application of the RF excitation signal to the next slice. Referring back to
(109) The center frequency of the RF refocusing signal of the second slice has a value shifted from the center frequency of the RF excitation signal of the second slice by f.sub.offset.
(110)
(111) Precession frequencies differ depending upon whether hydrogen atoms constitute a fat layer or muscle even when the object is located in magnetic fields having the same magnitude. Generally, a precession frequency of the hydrogen atoms constituting the fat layer is lower than that of the hydrogen atoms constituting other organs. When the RF is applied, as shown in
(112) Referring to
(113) The slice located between z/2+z.sub.off and z/2+z.sub.off is not a region intended by the user. For example, the MRI apparatus 100 may reverse the polarity of the Z-axis magnetic field gradient when the RF refocusing signal is applied so that the polarity of the Z-axis magnetic field gradient when the RF refocusing signal is applied is opposite to that of the Z-axis magnetic field gradient when the RF excitation signal is applied to obtain an MR signal for a slice intended by the user in consideration of the off-resonance component. That is, a positive magnetic field gradient Gz is applied when the RF excitation signal is applied, and a negative magnetic field gradient Gz is applied when the RF refocusing signal is applied. This is called gradient reversal technique.
(114)
(115) Referring to
(116) Referring to
(117) Consequently, the slice 330 commonly selected when the RF excitation signal is applied and when the RF refocusing signal is applied is located between z/2 and z/2. For example, the final region generating an MR signal includes only the on-resonance component and the off-resonance component does not affect the generated signal. As a result, the MR signal may be generated only for a slice region intended by the user.
(118)
(119) As described above, the position of a slice selected by an RF excitation signal is changed according to movement of the patient table 101. For example, an RF refocusing signal shifted by a predetermined value according to movement of the patient table 101 may be applied. At this time, the polarity of a gradient signal applied together with the RF refocusing signal is opposite to that of a gradient signal applied together with the RF excitation signal. As a result, center frequencies of the RF excitation signal and the RF refocusing signal have opposite offsets.
(120) When Equation 4 is used, the center frequency of the RF refocusing signal is shifted from that of the RF excitation signal by f.sub.offset=g.sub.zd/2r.
(121) Referring to
(122)
(123) Even when the gradient reversal technique is applied, the MRI apparatus 100 may adaptively control the RF refocusing signal to perform MRI for multiple slices. To this end, the RF refocusing signal for the second slice may be adjusted based on the gradient reversal technique. In this example, the first slice and the second slice may be simultaneously acquired.
(124) The center frequency of the RF refocusing signal for the first slice has a value shifted from the center frequency f.sub.s1 of the RF excitation signal by f.sub.offset=g.sub.zd/2r.
(125) For the second slice, in a case in which a magnetic field gradient Gz is applied when an RF excitation signal is applied and a magnetic field gradient Gz is applied when an RF refocusing signal is applied, a resonance frequency range corresponding to the second slice is changed even when the patient table 101 is not moved.
(126) Specifically, referring to
(127) In order to obtain an MR signal for the second slice, an RF excitation signal having a range of f.sub.s2,ex+f.sub.band/2 to f.sub.s2,exf.sub.band/2 may be applied and an RF refocusing signal having a range of f.sub.s2,re+f.sub.band/2 to f.sub.s2,ref.sub.band/2 may be applied. That is, in a case in which MR signals for multiple slices are acquired using the gradient reversal technique, the RF refocusing signal and the RF excitation signal for the second slice may have different ranges even when the patient table 101 is not moved.
(128) A case in which the patient table 101 is moved will be described. Referring to
(129) In order to select the slice located between z.sub.sz/2 and z.sub.s+z/2 by the RF refocusing signal as the first slice, an RF refocusing signal having a center frequency shifted from the center frequency of the RF excitation signal by f.sub.offset may be applied as described above.
(130) In a case in which the patient table 101 has not been moved, an RF refocusing signal having a center frequency f.sub.s2,re, i.e., an RF refocusing signal having a range of f.sub.s2,re+f.sub.band/2 to f.sub.s2,ref.sub.band/2, may be applied to the second slice. Since the patient table 101 has been moved in this embodiment, an RF refocusing signal having a range of f.sub.s2,re+f.sub.band/2+f.sub.offset to f.sub.s2,ref.sub.band/2+f.sub.offset may be applied to the second slice.
(131) In
(132) In an exemplary embodiment, the spins of the hydrogen atoms constituting the fat layer are set as the off-resonance component. However, the spins of the hydrogen atoms constituting the fat layer may be set as the on-resonance component. When a region to be detected is set as the on-resonance component, only an MR signal for the region may be detected.
(133) In
(134) When the MR signals for the multiple slices are acquired sequentially or in the interleaving fashion, a time interval is present between acquisition of an MR signal for the previous slice and acquisition of an MR signal for the next slice and the patient table 101 is moved for the time interval. For example, the offset of the center frequency based on the movement distance of the patient table 101 may be calculated as described above and the calculated offset may be additionally applied whenever advance to the next slice is performed.
(135) Specifically, movement of the patient table 101 is also considered between application of the RF refocusing signal to the previous slice and application of the RF excitation signal to the next slice. Referring back to
(136) The center frequency of the RF refocusing signal of the second slice has a value shifted from the center frequency of the RF excitation signal of the second slice by f.sub.offset.
(137) In addition, the MRI apparatus 100 may use a multi echo sequence. The multi echo sequence is technique of applying a plurality of RF refocusing signals after application of an RF excitation signal to acquire a plurality of echo signals using one RF excitation signal. When the multi echo sequence is applied, the center frequency of each refocusing RF may be shifted according to movement distance of the patient table 101 whenever each refocusing RF is applied.
(138)
(139) Referring to
(140) Static magnetic field is generated in the bore in which an object is lying (operation 311). The static magnetic field is generated by applying current to the main magnet 151, which surrounds the bore. Generally, the direction of the static magnetic field is parallel to the longitudinal axis of the magnet assembly 150.
(141) A gradient signal is applied to the generated static magnetic field to generate a gradient field (operation 312). Here, Z-when current is applied to the Z-axis gradient coils 152z, a Z-axis magnetic field gradient is generated in the bore. A slice may be selected by the Z-axis magnetic field gradient. After the Z-axis magnetic field gradient is generated, an X-axis magnetic field gradient and a Y-axis magnetic field gradient may be generated to encode a phase and a frequency.
(142) An RF excitation signal is applied to a slice to be imaged (operation 313). Since a resonance frequency is changed according to position on the Z axis, an RF excitation signal having a resonance frequency corresponding to the slice to be imaged may be applied to select the slice to be imaged. In the flowchart, the RF excitation signal is applied after the gradient signal is applied. However, the gradient signal and the RF excitation signal may be simultaneously applied.
(143) An RF refocusing signal having a center frequency shifted from the center frequency of the RF excitation signal by the calculated offset is applied (operation 314). When the RF refocusing signal has a center frequency shifted by the calculated offset, conformity between a slice selected by the RF excitation signal and a slice selected by the RF refocusing signal may be achieved.
(144) Subsequently, an MR signal is acquired from the slice to be imaged (operation 315). When TE/2 elapses after the RF refocusing signal is applied, an echo signal is generated. This echo signal becomes an MR signal for the slice to be imaged. Since conformity between the slice selected by the RF excitation signal and the slice selected by the RF refocusing signal is achieved by shifting the center frequency of the RF refocusing signal, an MR signal for a desired slice may be acquired without reduction in thickness of the slice.
(145) The above method may also be applied to a case in which MRI for multiple slices is performed. For each slice, the center frequency of the RF refocusing signal may be shifted by the calculated offset. When the MR signals for the multiple slices are simultaneously acquired, only movement of the patient table 101 may be considered between application of the RF excitation signal and application of the RF refocusing signal. When the MR signals for the multiple slices are acquired sequentially or in an interleaving fashion, movement of the patient table 101 is also considered between application of the RF refocusing signal to the previous slice and application of the RF excitation signal to the next slice.
(146) In addition, a multi echo sequence may be applied. When the multi echo sequence is applied, the center frequency of each refocusing RF may be shifted according to movement distance of the patient table 101 whenever each refocusing RF is applied.
(147)
(148) Referring to
(149) Static magnetic field is generated in the bore (operation 321).
(150) An excitation gradient is applied to the generated static magnetic field to generate an excitation gradient field (operation 322) and an RF excitation signal is applied to a slice to be imaged (operation 323). The excitation gradient signal and the RF excitation signal may be simultaneously applied. The excitation gradient signal forms a Z-axis magnetic field gradient and is applied together with the RF excitation signal.
(151) A refocusing gradient field is generated (operation 324) and an RF refocusing signal having a center frequency shifted from the center frequency of the RF excitation signal by the calculated offset is applied (operation 325). The refocusing gradient signal and the RF refocusing signal may be simultaneously applied. The refocusing gradient signal forms a Z-axis magnetic field gradient and is applied together with the RF refocusing signal. Since the gradient reversal technique is applied in this embodiment, the polarity of the refocusing gradient field is opposite to that of the excitation gradient field.
(152) When the RF refocusing signal has a center frequency shifted by the calculated offset, conformity between a slice selected by the RF excitation signal and a slice selected by the RF refocusing signal may be achieved.
(153) Subsequently, an MR signal is acquired from the slice to be imaged (operation 326). When TE/2 elapses after the RF refocusing signal is applied, an echo signal is generated. This echo signal becomes an MR signal for the slice to be imaged. Since conformity between the slice selected by the RF excitation signal and the slice selected by the RF refocusing signal is achieved by shifting the center frequency of the RF refocusing signal, an MR signal for a desired slice may be acquired without reduction in thickness of the slice.
(154) In addition, a multi echo sequence may be applied. When the multi echo sequence is applied, the center frequency of each refocusing RF may be shifted according to movement distance of the patient table 101 whenever each refocusing RF is applied.
(155) The above method may also be applied to a case in which MRI for multiple slices is performed using the gradient reversal technique. For each slice, the center frequency of the RF refocusing signal may be shifted by the calculated offset. Since the gradient reversal technique is applied in this embodiment, the RF refocusing signal and the RF excitation signal for the second slice may have different ranges even when the patient table 101 is not moved.
(156) Specifically, when the center frequency f.sub.s2,ex of the RF excitation signal for the second slice is a value shifted from the center frequency f.sub.s1 for the first slice by f.sub.s, the center frequency f.sub.s2,re of the RF refocusing signal for the second slice is a value shifted from f.sub.s1 by f.sub.s.
(157) When the MR signals for the multiple slices are simultaneously acquired, only movement of the patient table 101 may be considered between application of the RF excitation signal and application of the RF refocusing signal. When the MR signals for the multiple slices are acquired sequentially or in an interleaving fashion, movement of the patient table 101 is also considered between application of the RF refocusing signal to the previous slice and application of the RF excitation signal to the next slice. This is described in detail with reference to
(158) According to the MRI apparatus as described above and the control method thereof, conformity between the slice selected by the RF excitation signal and the slice selected by the RF refocusing signal may be achieved even when the patient table is moved during MRI.
(159) In addition, even when MRI for multiple slices is performed, the center frequency may be shifted for each slice considering movement distance of the patient table, thereby achieving conformity between the slice selected by the RF excitation signal and the slice selected by the RF refocusing signal.
(160) As apparent from the above description, according to the MRI apparatus and the control method thereof, the center frequency of the RF refocusing signal is shifted from that of the RF excitation signal considering movement distance of the patient table, thereby achieving conformity between the slice selected by the RF excitation signal and the slice selected by the RF refocusing signal.
(161) The described-above exemplary embodiments and advantages are merely exemplary and are not to be construed as limiting. The present teaching can be readily applied to other types of apparatuses. The description of exemplary embodiments is intended to be illustrative, and not to limit the scope of the claims, and many alternatives, modifications, and variations will be apparent to those skilled in the art.