Herbal Supplement ''Optimal Cholesterol''

Abstract

Optimal Cholesterol utilizes edible nature plant extracted by a variety of technology, it is one of the nature plant medicines which can treat atherosclerotic coronary heart disease, cerebral vascular disease and systemic vascular disease in the world. Its function is to soften the arterial blood vessels, and to treat arteriosclerosis, protect and repair the vascular endothelial cells; soft plaque, fibrous plaque and calcified plaque are removed during the process of preventing plaque rupture, bleeding, erosion and ulcer; regulate micro-circulation, enhance the ability of coronary artery blood supply, adjust heart rate, furthermore, there's none toxic side effects after long-term use.

Claims

1. the combination of rhodiola rosea, seabuckthorn with any two or more than two herb ingredients.

Description

DETAILED DESCRIPTION OF THE INVENTION

[0014] (1) The present invention concerns a new functional supplement (Chinese patent medicine), Optimal Cholesterol, that improves heart functions, belonging to the field of traditional Chinese medicine. It contains the following components (as measured per tablet): Rhodiola rosea: 200-400 mg, Seabuckthorn: 250-450 mg, Gynostemma: 250-450 mg, Wild Jujube: 20-60 mg, Epimedium Herb: 30-35 mg, Flatstem Milkvetch Seed: 20-40 mg.

[0015] (2) Preparation method for the new functional supplement: [0016] 1. Ethanol extraction: concentration 70-90 W/V, ethanol and crude slices ratio: 8:1. Two 8-hour periods, extraction time for each period 4 hours, temperature 80-100 C. [0017] 2. Water extraction: water and crude slices ratio shall be 10:1, two extractions with the first extraction lasting 3 hours and the second extraction lasting 2 hours, temperature 100 C. [0018] 3. Water extraction and ethanol precipitation: extract crude slices with water 3 times, combine the extracted fluids, then pressurise and concentrate, adjust concentration to 60-90 W/V, extract and precipitate with ethanol, recycle the ethanol, and then dry and crush.

[0019] (3) The present invention uses 6 herbs, all of which are classified as edible and medicinal plants and listed under plants permitted for use in supplements pursuant to provisions of the China Food and Drug Administration. They are safe to consume, effective and free of toxicity and side effects. Multiple chemical components can be obtained through extracting the above 6 herbs with a variety of methods, namely: multiple saponins, multiple flavones, alkaloids, triterpenoids, disaccharide, sterols, amino acids, vitamins A, B1, B2, C and E, dehydroascorbic acid, folic acid, carotene and a variety of trace elements.

[0020] (4) Toxic and side effects: none.

[0021] (5) The major functions of the invention are as follows: [0022] 1. Improving coronary artery vessels, combating myocardial ischemia and improving diastolic function in cardiac muscles; [0023] 2. Increasing nutritional blood flow and improves microcirculation in cardiac muscles, lowering myocardial oxygen consumption; [0024] 3. Strengthening the heart's contraction and pump function, improving the elasticity of vessels, and lowering resistance surrounding the vessels; [0025] 4. Expanding peripheral vessels, decreasing cardiac workload, and increasing coronary flow; [0026] 5. Increasing haemoglobin count and blood oxygen content, protecting the cardiac muscles and repairing damaged myocardial cells; [0027] 6. Promoting expansion of the L-type calcium channel, increasing calcium concentration in myocardial cells, strengthening the myocardial cells' contraction capability; [0028] 7. Binding well with angiotensin II receptor, allowing coronary artery vessels to maintain a good condition for blood supply when stimulated by heat and cold; [0029] 8. Protecting the diastolic function of the blood vessel endothelium damaged by lysophosphatidylcholine (LPC); [0030] 9. Lowering the total cholesterol (TC), diacylglycerol (TG), low-density lipoprotein cholesterin (LDL-C) and very low-density lipoprotein cholesterin (VLDL-C) in the serum, reducing the oxidative modification of LDL, inhibiting the up-regulated expression of mononuclear cell adhesion molecules, inhibiting inflammatory response, inhibiting the occurrence and development of coronary atherosclerosis, in order to achieve the goals of preventing the formation of thrombus and treating thrombus; [0031] 10. Anti-oxidation effect: the chemical components in the present product including beta-carotene, vitamin, folic acid and a variety of trace elements, which can effectively combat the oxidation of free radicals, and reverse the membrane potential functions that have been damaged. The components also have anti-aging and anti-fatigue effects. [0032] 11. The total flavonoids component in the product has a significant protective effect on myocardial ischemia, which improves arrhythmia and slowing heart rate caused by blood deficit in cardiac muscles; [0033] 12. Protective effect on liver and kidney: the saponin component in the present product can significantly reduce the increased SGDT and SGTP in animals in the CCL4-induced liver damage model, increase the A/G ratio, and reverse the increased AST and ALT in animal livers in the paracetamol model. It can also alleviate proteinuria in the Heymann nephritis rat model, lower blood viscosity, increase oxidation ability and improve kidney functions. In terms of the adenine-feeding induced chronic renal failure and renal tissue fibrosis in rats, not only does it have an anti-fibrosis effect, it can significantly improve kidney functions, where plasma endothelin and tumour necrosis factor show significant improvement and the haemoglobin count demonstrates an evident increase. Compared with the existing medicines in the market for coronary heart disease, Optimal Cholesterol has the following distinctive functions:

[0034] 1. Give priority to with softening arteries;

[0035] 2. Prevent thrombus fracture, surface erosion and ulceration;

[0036] 3. Gradually dissolve thrombus, it is effective for dissolving soft plaque, fibrous plaque and calcified plaque;

[0037] 4. Regulate micro-circulation, improve myocardial cell oxygen content and pump function;

[0038] 5. Has obvious therapeutic effect for irregular heartbeat.

[0039] So, it can replace a variety of western medicines.