APPARATUS FOR IRRADIATING GOODS LOADED IN TOTES
20220339310 · 2022-10-27
Inventors
- Dominique VINCENT (Louvain-la-Neuve, BE)
- Frédéric DESSY (Louvain-la-Neuve, BE)
- Jérémy BRISON (Louvain-la-Neuve, BE)
- Frédéric Stichelbaut (Louvain-La-Neuve, BE)
Cpc classification
A61L2/087
HUMAN NECESSITIES
A61L2202/14
HUMAN NECESSITIES
A61L2/24
HUMAN NECESSITIES
International classification
Abstract
An apparatus includes a radiation source configured to emit a radiation along an irradiation volume, and a conveyor configured to drive goods loaded in two or more transport units through the irradiation volume so as to expose a first portion of the goods to the radiation. The transport units may be loaded in totes of a tote height, and the conveyor may be configured to drive the totes. The totes may be arranged on top of one another, and each transport unit may be held in place in a tote by one or more support elements such that a total height of the totes is between 40% and 100% of the tote height, the transport units are loaded in a tote span over at least 70% of the total height, and the total height is centered relative to the tote height within about 20%.
Claims
1. An apparatus for irradiating goods with X-ray or electron beam radiation, comprising: a radiation source configured to emit radiation along an irradiation volume centered on an irradiation axis, wherein the radiation comprises X-rays or electron beam; a conveyor configured to drive goods loaded in two or more transport units, along a transverse axis normal to both the irradiation axis and the vertical axis, through the irradiation volume so as to expose a first portion of the goods to the radiation, wherein each of the transport units has a unit height measured along a vertical axis normal to the irradiation axis, wherein the transport units are loaded in a plurality of totes having tote height measured along the vertical axis from a bottom end located at a bottom end height to a top end located at a top end height, wherein one of the plurality of totes holds N transport units, with N ∈N and N 1, arranged on top of one another extending over a total height measured along the vertical axis from a bottom of a first transport unit located nearest to the bottom end of the tote at a bottom unit height to a top of an N.sup.th transport unit located nearest the top end of the tote at a top unit height, and wherein the conveyor is configured to drive the plurality of totes carrying N transport units loaded with the goods, wherein: the totes comprise support elements for supporting the transport units, wherein the support elements are positioned at different levels along the tote height of the totes, to adapt a distance separating two adjacent support elements along the vertical axis to a height of the corresponding transport unit, and each transport unit is held in place in a tote by one or more support elements whose levels along the tote height are selected such that the total height is between 40% and 100% of the tote height, the N transport units are loaded in a tote span over at least 70% of the total height, and the total height is centered relative to the tote height within ±20%.
2. The apparatus of to claim 1, further comprising a processing control unit configured to perform at least one of: measuring the unit height of the transport units prior to loading them into the totes, weighing the transport units and determining corresponding densities of the transport units, determining a target total height according to a height of the irradiation volume measured along the vertical axis and selecting the N transport units to be loaded in each tote to reach a total height lower than the tote height and comprised within ±10% of the target total height, for each tote, optimizing the height of the irradiation volume to the total height of the transport units loaded in the corresponding totes, determining a loading scheme of the transport units, assigning which transport units are to be loaded in which totes, and assigning a loading position of each transport unit in a tote along the vertical axis according to the measured unit heights of the transport units, so as to maximize a filling ratio of the total height to the tote height, and/or according to the determined densities so that the N transport units loaded in a tote have similar densities within ±25%, or assigning a position for each support element optimized according to the unit heights of the transport units to minimize a gap ratio of a total gap separating every two adjacent transportation units in a same tote to the total height.
3. The apparatus of claim 2, further comprising a loading station configured to load the transport units onto the totes according to at least one of the loading scheme or the loading position.
4. The apparatus of claim 3, wherein the loading station is further configured to position the support elements at positions optimized according to the unit heights of the transport units to minimize the gap ratio.
5. The apparatus of claim 2, wherein transport units of similar densities are loaded into one or a series of totes, and wherein the conveyor is configured to drive the one or the series of totes through the irradiation volume at a speed dependent on an average density of the transport units loaded in the one or the series of totes.
6. The apparatus of claim 1, further comprising a rotating element configured for rotating the totes by an angle of rotation and wherein the conveyor is configured to drive several times the totes through the irradiation volume such as to expose second, third, and so on portions of the goods to the radiation each time the totes are rotated by the angle of rotation.
7. The apparatus of claim 1, wherein the apparatus is configured for one of: one level irradiation of the totes, using a scan horn configured to over-scan such that the irradiation volume includes the whole tote height and the first portions of the goods of all the N transport units loaded in a tote are exposed to a required dose in a single pass, or two levels irradiation of the totes, using a scan horn configured to under-scan such that the irradiation volume does not include the whole tote height and the first portions of the goods of the N transport units loaded in a tote are exposed to the required dose in two passes, with a first pass with a first selection of transport units loaded in an upper half portion of the tote, and a second selection of transport units loaded in a lower half portion of the tote, and with a second pass with the first selection of transport units loaded in the lower half portion of the tote and the second selection of transport units loaded in the upper half portion of the tote.
8. The apparatus of claim 1, wherein the apparatus is configured for two levels irradiation of the totes, the apparatus comprising a swapping unit configured to transfer the transport units loaded in the upper half portion of a first tote to the lower half portion of a second tote and the transport units loaded in the lower half portion of the first tote to the upper half portion of the second tote, and for driving the second tote through the irradiation volume.
9. The apparatus of claim 1, wherein the conveyor comprises an elevated track on which the totes are suspended and driven, or a roller conveyor on which the totes stand and are driven.
10. The apparatus of claim 1, wherein: the tote height is between 500 and 650 cm, the height of the transportation unit is between 50 and 380 cm, and a gap separating two adjacent transportation units in a same tote is between 8 and 30 cm.
11. The apparatus of claim 1, wherein a dose uniformity ratio defined as a ratio of a maximum dose to a minimum dose deposited into a good along the irradiation axis as a function of the vertical axis between a bottom of the transportation unit and a top of the transportation unit is not more than 1.4 for a uniform good density of 0.1 g/cm.sup.3.
12. A method for irradiating goods loaded in transportation units with X-ray or electron beam radiation, the method comprising: loading transportation units onto the totes provided with the support elements which support the transportation units of the apparatus of claim 1, driving the totes through the irradiation volume, along the transverse axis to expose the first portion of the goods, and irradiating the transportation units with the radiation as the totes are driven through the irradiation volume.
13. The method of claim 12, wherein after a pass through the irradiation volume to expose a portion of the goods, the totes are rotated by a rotating angle and driven back through the irradiation volume, to expose a different portion of the goods contained in the transport units.
14. The method of claim 12, wherein the conveyor is configured for a two levels irradiation of the totes, wherein the apparatus comprises a swapping unit and wherein the method further comprises: transferring the transport units loaded in an upper half portion of a first tote to the lower half portion of a second tote, transferring the transport units loaded in a lower half portion of the first tote to the upper half portion of the second tote, and driving the second tote through the irradiation volume.
15. The method of claim 12, wherein a scanning horn and the irradiation axis are maintained constant during a whole process irrespective of the heights of the transport units and densities of the goods.
Description
BRIEF DESCRIPTION OF THE FIGURES
[0062] For a fuller understanding of the nature of the present disclosure, reference is made to the following detailed description taken in conjunction with the accompanying drawings in which:
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DETAILED DESCRIPTION
[0090] As illustrated in
[0091] The gist of the present disclosure is to load one or more transport units (1.i) in totes (5) and to configure the conveyor (3) for driving the totes (5) carrying N transport units (1.i) containing the goods through the irradiation volume (Xv), wherein N 1. The totes may have a tote height (h5=H51−h50) measured along the vertical axis (Z) from a bottom end located at a bottom end height (h50) to a top end located at a top end height (h51). A tote (5) holds N transport units, with N E N and N 1, arranged on top of one another extending over a total height (ht=Ht1−Ht0) measured along the vertical axis (Z) from a bottom of a first transport unit (1.1) located nearest to the bottom end of the tote (5) at a bottom unit height (Ht0) to a top of an N.sup.th transport unit (1.N) located nearest the top end of the tote at a top unit height (Ht1).
[0092] Referring to
[0096]
Transport Units and Totes
[0097] The goods to be irradiated can be any type of goods suitable for being treated by radiation. For example, for sterilization processes, the goods can be foodstuff, medicine, medical equipment, electronic components, garments, and the like. For polymerization, crosslinking and shrink fitting, the goods can comprise polymers and polymer precursors. The goods can be stacked on pallets. The goods can be stored in containers made of a material substantially transparent to the radiation. The goods can also be stored in containers standing on pallets. Pallets and containers holding the goods are collectively referred to as transport units (1.i), regardless of whether they are open structures or closed containers.
[0098] Referring to
[0099] A tote may comprise a structure comprising support elements for holding N transport units one on top of the other. The support elements can be positioned at different levels along the tote height (h5). Totes can be open or closed structures. If the totes are closed structures, the portions exposed to the radiation may be made of a material substantially transparent to X-rays or electron beam.
[0100] N is a natural number and can take any value as long as the total height (ht) remains smaller than the tote height (h5), i.e., ht<h5.
[0101] The footprint of the totes over a plane (X, Y) is adapted for receiving the transport units. As mentioned supra, a standard size of pallets in Europe is 100×120 cm.sup.2, such that the totes should have a footprint slightly larger than the transport unit footprint, i.e., about 110 to 120 cm per 130 to 140 cm. The tote height (h5) may differ for one-level and two-level systems. In one-level systems irradiation proceeds in an overscan mode, and in two-level systems it proceeds in an underscan mode. Assuming a same scan horn (11h) is used having a scanning width (hx) of e.g., 300 cm, measured along the vertical axis (Z), then the total height (ht) of the transport units stacked in a tote will have to be smaller than the scanning width (hx) for one-level systems and larger than the scanning width (hx) for two-level systems.
[0102] Although a same tote height (h5) can be used for any value of the total height (ht), if an apparatus is designed for being operated only as a one- or two-level system, the tote height (h5) can be optimized to fit the scanning width (hx) and to the corresponding total height (ht) of transport units (1.i) stacked in one tote. For example, assuming N=2 transport units (1.1, 1.2) of unit heights, h11=120 cm and h12=140 cm, with a gap of height, hv1=15 cm, between the two transport units, yields a total height, ht=120+140+15=275 cm. A scan horn having a scanning width hx=300 cm>ht would be suitable for a one-level system. The tote height (h5) could be of the order of 290 to 350 cm, or of 300 to 330 cm for a one-level system. The same applies to a tote (5) holding a single transport unit (1.1) of unit height of e.g., h11=270 cm.
[0103] By contrast, a tote height (h5) of the order of 500 to 650 cm, or of 550 to 620 cm, or of 580 to 610 cm may be required for holding N=2 transport units (1.1, 1.2) of heights h11=h12=270 cm with a gap of height, hv=15 m, yielding a total height of 2×270+15=555 cm. A tote loaded with the two transport units would be suitable for treatment in a two-level system using a scan horn of scanning width, hx=300 cm. The foregoing figures are purely illustrative to give an order of magnitude of the dimensions. They can vary within ±20% without departing from the embodiments of the present disclosure.
[0104] As shown with the transport units #(1.j), (1.(j+1)), (1.(j+2)) illustrated in
[0105] The goods contained in a volume of the transport units (1.i) typically have densities comprised between 0.05 to 0.5 g/cm.sup.3. The density of the transport units is relevant as absorption of the radiation as it penetrates through the goods increases with density. For this reason, the transport units may be sorted as a function of their densities, and the N transport units loaded in one tote may have similar densities. In some embodiments, batches of several totes may be loaded with transport units of similar densities. This way, the totes of such batches can be driven sequentially through the irradiation volume (Vx) at a constant speed.
Optimization of the Loading of Transport Units (1.i) into Each Tote (5)
[0106] In some embodiments of the present disclosure, the apparatus may comprise a processing control unit (PCS) (7) configured for optimizing the sequence of loading of transport units within a tote and over different totes (5). A PCS (7) can comprise or be coupled to measurement equipment for measuring one or more parameters on the transport units, such as the unit height (h1.i), a weight, and/or a density of the transport units (1.i). As shown in
[0107] The PCS (7) may be configured for determining a loading scheme of the transport units (1.i), assigning which transport units (1.i) are to be loaded in which totes and assigning a loading position of each transport unit (1.i) in a tote along the vertical axis. The totes and loading positions transport units can be assigned, [0108] according to the unit heights (h1.i) of the transport units thus measured, such as to maximize a filling ratio (ht/h5) of the total height (ht) to the tote height (h5), and/or [0109] according to the densities thus determined such that the N transport units (1.1-1.N) loaded in a tote have similar densities within +25%.
[0110] The PCS (7) can also be configured for assigning a position for each support element (5s) optimized according to the unit heights of the transport units (1.i) to maximize the exposure ratio or, in other words, to minimize a gap ratio Σ.sub.t.sup.N−1 hvi/ht) of a total gap (Σ.sub.t.sup.N hvi) separating every two adjacent transportation units (1.i, 1.(i+1)) in a same tote to the total height (ht).
[0111] As shown in
The Conveyor (3)
[0112] The conveyor (3) can be in the form of an elevated track on which the totes (5) are suspended and driven, as illustrated in
[0113] Examples of conveyors designs are illustrated in
[0114] In some embodiments, transport units (1.i) of similar densities may be loaded into one or a series of totes (5) by the loading station (4) and the conveyor may be configured for driving the one or the series of totes through the irradiation volume at a speed dependent on an average density of the transport units (1.i) loaded in the one or the series of totes.
[0115] The conveyor (3) may be equipped with a rotating element (3r) configured for rotating the totes (5) by an angle of rotation (θ). The conveyor (3) may be configured for driving several times the totes through the irradiation volume such as to expose second, third, and so on portions of the goods to the radiation each time the totes are rotated by the angle of rotation. In some embodiments, θ=180° and the conveyor (3) may drive the totes for a second pass to expose an opposite portion to the one first exposed to the radiation before evacuating the treated totes (5x). Alternatively, the rotating element (3r) can be located within the irradiation volume (Vx) to rotate the tote as it is being irradiated.
[0116] A same structure can be used for conveying the totes in both one-level and two-level systems. The only difference is in a scanning ratio (hx/ht) between the scanning width (hx) of the scan horn and the total height (ht). A scanning ratio hx/ht>1 may define an overscanning mode suitable for one-level systems and a scanning ratio hx/ht<1 may define an underscanning mode suitable for two-level systems.
[0117] As shown in
[0118] In two-level systems, the PCS (7) can also be configured for optimizing the number and sequence of second totes, as well as the positions of the support elements of the empty second totes (5e) waiting for receiving the transport units (1.ix) from the first totes (5x) after a first exposure to the radiation. The empty second totes may be parked vis-à-vis the first totes (5x), with the support elements (5s) at the corresponding positions for swapping the transport units up-down and down-up. As illustrated in
[0119] In another embodiment illustrated in
[0120] These operations may be repeated for each transport unit loaded in a first tote, for all the first totes having received the first-level irradiation. The second totes thus loaded may be ready for driving the transport units through the irradiation volume (Vx) to receive the second-level irradiation of the two-level system. The empty first totes can be evacuated and refurbished before being reloaded with a new set of N transport units. The number and positions of the support elements can be adapted to the new load of transport units as explained supra.
One-Level System
[0121] As explained supra and as illustrated in
[0122] A one-level system may be simpler to operate than two-level systems and may be faster than a two-level system. Actually, the process throughputs of one-level systems and two-level systems are not so different for the following reasons. Although the transport units loaded in a tote in a two-level system may pass a second time through the irradiation volume (Vx), the total height (ht) of transport units being driven through the irradiation volume (Vx) in one pass of a two-level system can be about the double of the total height (ht) in a one-level system.
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Two-Level System
[0124] As illustrated in
[0125] Though not mandatory, in two-level systems, the totes may comprise a support element (5s) located to within ±30 cm, or within ±20 cm, or within ±10 cm, or within ±5 cm from a half-height (½h5) of the tote, defined as a plane normal to the vertical axis (Z) located at equal distance (½ h5) from both bottom end and the top end. This way, the swap of transport units between bottom and top half portions of the totes may allow depositing during the second pass a second pass dose which is complementary with the first pass dose deposited during the first pass, and thus yielding a lower value of DUR. At the same time, care should be taken to centre the total height (ht) approximately on the irradiation axis (X). The support elements (5s) in the second tote may therefore not necessarily be at the same levels as in the first tote.
[0126] In case a tote is loaded with transport units of similar heights, the support elements (5s) of the second tote can simply be located at the same positions as in the first tote. In case, however, transport units of different heights are loaded in a tote, as shown in
[0127] Because the totes (5) for two-level systems usually have large tote heights (h5) of the order of 500 to 650 cm, for stability issues, the totes (5) may be driven with a conveyor (3) comprising an elevated track on which the totes (5) are suspended.
Dose Deposition Distribution Along the Irradiation Axis (X)
[0128] The dose deposition distribution along the irradiation axis (X) into a transport unit (1.i) by a radiation (11x) is illustrated in
[0129] In an alternative embodiment, the rotating element may be located within the irradiation volume, such that each tote (5) rotates continuously or intermittently about the vertical axis (Z) as it stands within the irradiation volume (Vx). For example, the conveyor may comprise a rotating element configured for rotating (M— 1) times a tote by an angle θ=2π/M rad to successively expose M portions of the transport units (1.i) loaded in the tote to the irradiation volume (Vx). This solution yields the same advantages in terms of enhanced homogeneity as discussed supra in relation with
[0130] In yet another embodiment, the apparatus may comprise a second source of radiation configured for emitting a radiation along a second irradiation volume centred on a second irradiation axis such as to irradiate a second portion of the transport units (1.i). The second irradiation axis may be parallel to, or coaxial with the first irradiation axis (X), and irradiation proceeds in a direction opposite to the irradiation by the first source of radiation (11). This way, two opposite portions of the transport units can be irradiated simultaneously, thus increasing the throughput accordingly. This solution is, however, substantially more expensive than the previous ones, as it requires a second source of radiation.
Two-Level Systems Using Totes (5) Vs State-of-the-Art Double Track Systems
[0131] The gist of the present disclosure applied to two-level systems, wherein transport units (1.i) are stacked one on top of the other in totes rather than on two superimposed tracks (3) separated from one another by a separation distance (h3) is that the distribution of the transport units can be varied and optimized, minimizing the gaps (hvi) between adjacent transport units (1.i, 1.(i+1)). This has several advantages.
[0132] First, the total gap height (Σ.sub.ihvi)) can be minimized. The larger the total gap height, the larger the amount of wasted energy. In state-of-the-art superimposed tracks, the single gap height (hv1) cannot be controlled and depends on the unit height (h11) of the transport unit (1.1) loaded in the lower track as hv1=h3−h11. The waste of energy due to the larger gap height (hv1) in the state-of-the-art superimposed tracks is illustrated for a two-level system, on the one hand, [0133] In
[0135] It can be seen from
[0136] Second, with state-of-the-art two superimposed tracks the number N of transport units which can be stacked on top of one another is limited to N=2 for all unit heights (h1i) lower than the separation distance (h3) between the two tracks (i.e., ∀Vh1i<h3). By using totes according to the present disclosure, more than two transport units can be stacked on top of one another as long as the total height (ht) remains lower than the tote height (h5) (i.e., ht<h5).
[0137] For example, two superimposed tracks separated from one another by a separation distance, h3=300 cm can be compared with a tote (5) of tote height, h5=600 cm. If transport units (1.i) of unit height, h1i=120 cm must be treated, two transport units can be irradiated at a time with the two superimposed tracks, with a gap height, hv1=300−120=180 cm. The exposure ratio, Σ.sub.i=1.sup.2h1i/ht, defining the proportion of goods distributed along the total height (ht) is equal to 2×120/(2×120+180)=57% of the total height. This means that 43% of the total height (ht) is made of gaps, thus wasting 43% of the energy of the emitted radiation.
[0138] With a tote of tote height, h5=600 cm, four transport units of unit height, h1.i=120 cm, can be loaded in one tote, with hvi=15 cm gaps between every two transportation units, yielding a total gap height, E.sub.i=1.sup.3hvi,=3×15 cm=45 cm only, with an exposure ratio, E.sub.i=1.sup.4 h1i/ht=4×120/(4×120+3×15)=91% of the total height filled by goods during irradiation. Only 9% of the total height (ht) is made of gaps. This example illustrates the advantage of the present disclosure over the state-of-the-art superimposed tracks systems, yielding a throughput twice as high with four transport units being irradiated at each pass instead of two for the superimposed tracks, and with an exposure ratio which is 34% higher, yielding a corresponding saving of energy.
[0139]
[0140] According to the present disclosure, the dose uniformity ratio (DURx) defined as the ratio (DMx/Dmx) of the maximum dose (DMx) to a minimum dose (Dmx) deposited into a good along the irradiation axis (X) as a function of the vertical axis (Z) between a bottom of the transportation unit (1.i) and a top of the transportation unit (1.i) may not be more than 1.4, or not more than 1.3, or not more than 1.15, for a uniform good density of 0.1 g/cm.sup.3.
[0141] Third, by using totes, a suspended track can be used to drive the totes loaded with transport units through the irradiation volume (Vx) rather than using motorized roller conveyors as in conventional installations. A suspended track is advantageous because it requires less moving and motorized parts exposed to the aggressive environment within and in the area surrounding the irradiation volume (Vx). Unlike roller conveyors, a suspended track drives the totes by means of a chain or a cable which is pulled by a motor which can be located well remote from the irradiation volume (Vx), thus prolonging the service life of the equipment, and reducing the number of failures requiring stopping the conveyor. Note that roller conveyors can be used with the present disclosure if desired.
Method for Irradiating Goods with a Radiation
[0142] The apparatus of the present disclosure can advantageously be used in a method for irradiating with a radiation selected among X-rays and electron beam goods contained in transport units (1.i). The method may comprise the following steps: [0143] providing an apparatus as discussed supra, [0144] loading transportation units (1.i) onto the totes (5) provided with the support elements (5s) which support the transportation units (1.i) as discussed supra, [0145] driving the totes (5) through the irradiation volume centred on the irradiation axis (X), along the transverse axis (Y) to expose a first portion of the goods, and [0146] irradiating the transportation units (1.i) with the radiation (11x) as the totes (5) are driven through the irradiation volume.
[0147] To decrease the value of DURx, after a pass through the irradiation volume to expose a portion of the goods, the thus irradiated totes (5x) may be rotated by the rotating angle (0) and driven back through the irradiation volume, to expose a different portion of the goods contained in the transport units (1.i). Alternatively, the totes can be rotated within the irradiation volume (Vx).
[0148] In some embodiments, the method may apply a two-level irradiation of the totes (5) and the apparatus may comprise a swapping unit (9) as discussed supra. In this embodiment, the method may comprise the steps of: [0149] transferring the transport units (1.i) loaded in the upper half portion of a first tote (5) to the lower half portion of a second tote (5) and [0150] transferring the transport units (1.i) loaded in the lower half portion of the first tote (5) to the upper half portion of the second tote (5), and [0151] driving the second tote through the irradiation volume (Vx).
[0152] The present disclosure has the advantage that all irradiation parameters including the radiation energy, the scanning horn (11h), and the irradiation axis (X) can be maintained constant during the whole process for irradiating transport units of different unit heights (h1i) and densities. The driving rate of the totes through the irradiation volume (Vx) may be adapted to the densities of the transport units loaded in each tote (5).
[0153] The throughput can be increased compared with state-of-the-art installations, as more than two transport units can be loaded in one tote, as long as the total height (ht) remains smaller than the tote height (h5) (i.e., ht<h5).
[0154] As the total gap height, Σ.sub.i.sup.N−1hvi, can be reduced, and the exposure ratio, Σ.sub.i=1.sup.N h1i/ht, increased accordingly, the efficacy of the process is substantially enhanced compared with a state-of-the-art two superimposed tracks system, with less radiation wasted through the gap between two transportation units.
[0155] The apparatus and method of the present disclosure can be applied for both one-level and two-level irradiation techniques.
[0156] A higher minimum dose (Dmx) can be deposited with an apparatus according to the present disclosure as with state-of-the-art apparatuses using a same source of radiation (11).