GROWTH PROMOTING PEPTIDES, AND USES THEREOF

Abstract

A natural peptide comprising a cellular growth promoting fragment of a protein selected from SEQ ID NO's: 1 to 13, and a composition comprising a plurality of growth promoting peptides, is described. Also disclosed is the use of the peptides and compositions in prevention of ageing of human skin, treatment of diseases or conditions characterised by damaged epithelial cells or tissue such as colon cancer and peripheral inflammatory disorders, and wound treatment. Specific pea and rice protein derived peptides are described in SEQ ID NO's: 15 to 505, and 546 to 704.

Claims

1.-19. (canceled)

20. A peptide comprising SEQ ID NO: 222, or a substantially similar growth promoting sequence having 1 to 3 amino acid alterations compared SEQ ID NO: 222, in which the or each amino acid alteration is independently selected from insertion, addition, deletion and substitution of an amino acid, wherein the peptide is up to 50 amino acids in length.

21. The peptide of claim 20, wherein the peptide is growth promoting.

22. The peptide of claim 20, wherein the peptide consists of SEQ ID NO: 222.

23. The peptide of claim 20, wherein the peptide is a modified peptide.

24. The peptide of claim 20, wherein the peptide is chemically modified by modifications to side chains, incorporation of a protecting group, incorporation of unnatural amino acids and/or their derivatives during peptide synthesis, and imposing conformational constraint on the peptide.

25. A conjugate comprising a peptide of claim 20, conjugated, linked or fused to a binding partner, in which the binding partner is optionally selected from a polyethylene glycol (PEG) polymer, a molecular weight increasing compound, a lipophilic group, or an antibody molecule.

26. A composition comprising the peptide of claim 20.

27. The composition of claim 26, wherein the composition in the form of a powder.

28. The composition of claim 26, wherein the composition is formulated for topical application to the skin of a human.

29. The composition of claim 26, wherein the composition is in the form of a serum, gel, cream, lotion, ointment, cream, emulsion, anhydrous composition, aqueous dispersion, oil, milk, balsam, foam, hydro-alcoholic solution, hydro-glycolic solution, cosmetic, personal care product, hydrogel, liniment, sera, soap, dusting powder, paster, semi solid formulation, shampoo, conditioner, any rinse off formulation, talc, mousse, power, spray, aerosol, solution, suspension, syrup, elixir, polysaccharide film, patches, gel patches, bandages, an adhesive system, water in oil emulsion, oil in water emulsion and silicone emulsion.

30. The composition of claim 26, wherein the composition further comprises a cosmetically or pharmaceutically acceptable excipient, optionally selected from the group consisting of an emollient, diluent, carrier, binder, lubricant, suspending agent, coating agent, preservative, stabiliser, dye, vehicle, solubilising agent, base, emulsifying agent, fragrance, humectant, and surfactant.

31. The composition of claim 26, wherein the composition is a personal care composition, a pharmaceutical composition, a cosmetic composition, a food or beverage or a nutritional supplement.

32. A method of slowing ageing of human skin, or to treat visible signs of ageing, wherein the method comprises topically administering to the skin of a human the peptide of claim 20.

33. A method for treating a wound in a mammal, wherein the method comprises topically administering to the wound the peptide of claim 20.

34. A wound dressing comprising the peptide of claim 20, wherein the dressing is optionally selected from the group consisting of a bandage or a plaster.

Description

BRIEF DESCRIPTION OF THE FIGURES

[0284] FIGS. 1 to 100: Effect of synthetic peptides of the invention on proliferation of Human Dermal Fibroblasts (HDF).

[0285] FIG. 101: Effect of synthetic peptide of the invention (SEQ ID NO: 42) on elastin synthesis of Human Dermal Fibroblasts (HDF).

[0286] FIG. 102: Effect of synthetic peptide of the invention (SEQ ID NO: 42) on collagen synthesis of Human Dermal Fibroblasts (HDF).

[0287] FIG. 103: Effect of synthetic peptide of the invention (SEQ ID NO: 701) on elastin synthesis of Human Dermal Fibroblasts (HDF).

[0288] FIG. 104: Effect of synthetic peptide of the invention (SEQ ID NO: 701) on collagen synthesis of Human Dermal Fibroblasts (HDF).

[0289] FIG. 105: Effect of synthetic peptide of the invention (SEQ ID NO: 246) on elastin synthesis of Human Dermal Fibroblasts (HDF).

[0290] FIG. 106: Effect of synthetic peptide of the invention (SEQ ID NO: 246) on collagen synthesis of Human Dermal Fibroblasts (HDF).

[0291] FIG. 107: Effect of synthetic peptide of the invention (SEQ ID NO: 284) on elastin synthesis of Human Dermal Fibroblasts (HDF).

[0292] FIG. 108: Effect of synthetic peptide of the invention (SEQ ID NO: 245) on elastin synthesis of Human Dermal Fibroblasts (HDF).

[0293] FIG. 109: Effect of synthetic peptide of the invention (SEQ ID NO: 245) on collagen synthesis of Human Dermal Fibroblasts (HDF).

[0294] FIG. 110. shows the integrity controls and viability controls for the assay system.

[0295] FIG. 111. % of elastin expression in superficial dermis compared to control (water or DMSO) for peptides P1, P2 and P3

* shows significant increases of elastin expression in superficial AND middle dermis.

[0296] FIG. 112. % of elastin expression in middle dermis compared to control (water or DMSO) for peptides P1, P2 and P3.

* shows significant increases of elastin expression in superficial AND middle dermis.

[0297] FIG. 113. % of cell proliferation in the basal layer of epidermis compared to control (water or DMSO) for peptides P6 and P8, and peptide compositions P9 and P10

* shows significant increases.

[0298] FIG. 114. Histological analysis of the elastic fibers (+catechin, 200)

[0299] FIG. 115. Immunohistochemical evaluation of the mitotic index (Ki67, 400)

DETAILED DESCRIPTION OF THE INVENTION

Example 1Cell Proliferation Assay

[0300] BrDu is incorporated into newly synthesised DNA strands of actively proliferating cells. Following partial denaturation of double stranded DNA, Brdu is detected immunochemically allowing the assessment of the population of cells which are synthesizing DNA.

[0301] Human Dermal Fibroblasts (HDFSigma 10605a) were seeded in a 96 well plate at 10,000 cells per well in DMEM containing 10% fetal calf serum (FCS), 1% Pen/strep, 1% L-glutamine and allowed to adhere for 24 h.

[0302] Following the initial 24 h incubation the cells were incubated with 5 g/ml, 0.5 g/ml or 0.05 g/ml synthetic peptide for 24 h respectively.

[0303] After 18 h incubation with synthetic peptides 20 l BrDu reagent was added to each well.

[0304] At 24 h incubation the cell were fixed and the amount of 2-DG6P was measured using the BrdU Cell Proliferation Assay, all steps were carried out according to the manufacturer's instructions.

[0305] Results were calculated as a percentage of the untreated control. An increase in optical density reading indicates greatER incorporation of BrDu and increase cell proliferation.

[0306] The results are shown in FIGS. 1-100 and Table 1 below.

TABLE-US-00009 TABLE 1 FIG. SEQ ID INCREASE IN NO NO: PROLIFERATION 1 121 48% 2 105 40% 3 249 30% 4 226 30% 5 84 20% 6 330 18% 7 181 33% 8 83 32% 9 247 28% 10 97 26% 11 74 29% 12 13 168 14 151 15 470 119% 16 257 118% 17 256 117% 18 457 114% 19 499 113% 20 253 112% 21 222 110% 22 272 97% 23 252 111% 24 248 86% 25 472 77% 26 365 58% 27 502 68% 28 496 51% 29 98 49% 30 454 38% 31 85 35% 32 453 25% 33 158 21% 34 464 18% 35 73 16% 36 359 15% 37 124 15% 38 112 15% 39 733 40 728 41 727 42 730 43 731 44 148 45 343 46 345 47 484 48 729 49 456 50 494 51 723 52 722 53 498 54 475 13% 55 718 56 337 8% 57 500 6% 58 717 59 297 60 340 61 719 62 726 63 725 64 724 65 720 66 721 67 503 125% 68 474 121% 69 504 119% 70 114 119% 71 505 118% 72 482 113% 73 479 106% 74 477 81% 75 410 73% 76 475 69% 77 497 58% 78 480 102% 79 463 100% 80 465 96% 81 467 90% 82 461 85% 83 341 83% 84 468 82% 85 285 81% 86 496 81% 87 146 80% 88 478 76% 89 452 76% 90 495 68% 91 403 51% 92 455 47% 93 270 47% 94 501 43% 95 473 41% 96 39% 97 471 38% 98 460 38% 99 93 26% 100 462 15%

[0307] FIG. 1 shows an increase in HGF cell proliferation of 48% when incubated with SEQ ID NO: 121.

[0308] FIG. 2 shows an increase in HGF cell proliferation of 40% when incubated with SEQ ID NO: 105.

[0309] FIG. 3 shows an increase in HGF cell proliferation of 30% when incubated with SEQ ID NO: 249.

[0310] FIG. 4 shows an increase in HGF cell proliferation of 30% when incubated with SEQ ID NO: 226.

[0311] FIG. 5 shows an increase in HGF cell proliferation of 20% when incubated with SEQ ID NO: 84.

[0312] FIG. 6 shows an increase in HGF cell proliferation of 18% when incubated with SEQ ID NO: 330.

[0313] FIG. 7 shows an increase in HGF cell proliferation of 33% when incubated with SEQ ID NO: 181.

[0314] FIG. 8 shows an increase in HGF cell proliferation of 32% when incubated with SEQ ID NO: 83.

[0315] FIG. 9 shows an increase in HGF cell proliferation of 28% when incubated with SEQ ID NO: 247.

[0316] FIG. 10 shows an increase in HGF cell proliferation of 26% when incubated with SEQ ID NO: 97.

[0317] FIG. 11 shows an increase in HGF cell proliferation of 29% when incubated with SEQ ID NO: 74.

[0318] FIG. 15 shows an increase in HGF cell proliferation of 119% when incubated with SEQ ID NO: 470.

[0319] FIG. 16 shows an increase in HGF cell proliferation of 118% when incubated with SEQ ID NO: 257.

[0320] FIG. 17 shows an increase in HGF cell proliferation of 117% when incubated with SEQ ID NO: 256.

[0321] FIG. 18 shows an increase in HGF cell proliferation of 114% when incubated with SEQ ID NO: 457.

[0322] FIG. 19 shows an increase in HGF cell proliferation of 113% when incubated with SEQ ID NO: 499.

[0323] FIG. 20 shows an increase in HGF cell proliferation of 112% when incubated with SEQ ID NO: 253.

[0324] FIG. 21 shows an increase in HGF cell proliferation of 110% when incubated with SEQ ID NO: 222.

[0325] FIG. 22 shows an increase in HGF cell proliferation of 97% when incubated with SEQ ID NO: 272.

[0326] FIG. 23 shows an increase in HGF cell proliferation of 111% when incubated with SEQ ID NO: 252.

[0327] FIG. 24 shows an increase in HGF cell proliferation of 86% when incubated with SEQ ID NO: 248.

[0328] FIG. 25 shows an increase in HGF cell proliferation of 77% when incubated with SEQ ID NO: 472.

[0329] FIG. 26 shows an increase in HGF cell proliferation of 58% when incubated with SEQ ID NO: 365.

[0330] FIG. 27 shows an increase in HGF cell proliferation of 68% when incubated with SEQ ID NO: 502.

[0331] FIG. 28 shows an increase in HGF cell proliferation of 51% when incubated with SEQ ID NO: 496.

[0332] FIG. 29 shows an increase in HGF cell proliferation of 49% when incubated with SEQ ID NO: 98.

[0333] FIG. 30 shows an increase in HGF cell proliferation of 38% when incubated with SEQ ID NO: 454.

[0334] FIG. 31 shows an increase in HGF cell proliferation of 35% when incubated with SEQ ID NO: 85.

[0335] FIG. 32 shows an increase in HGF cell proliferation of 25% when incubated with SEQ ID NO: 453.

[0336] FIG. 33 shows an increase in HGF cell proliferation of 21% when incubated with SEQ ID NO: 158.

[0337] FIG. 34 shows an increase in HGF cell proliferation of 18% when incubated with SEQ ID NO: 464.

[0338] FIG. 35 shows an increase in HGF cell proliferation of 16% when incubated with SEQ ID NO: 73.

[0339] FIG. 36 shows an increase in HGF cell proliferation of 15% when incubated with SEQ ID NO: 359.

[0340] FIG. 37 shows an increase in HGF cell proliferation of 15% when incubated with SEQ ID NO: 124.

[0341] FIG. 38 shows an increase in HGF cell proliferation of 15% when incubated with SEQ ID NO: 112.

[0342] FIG. 54 shows an increase in HGF cell proliferation of 13% when incubated with SEQ ID NO: 475.

[0343] FIG. 56 shows an increase in HGF cell proliferation of 8% when incubated with SEQ ID NO: 337.

[0344] FIG. 57 shows an increase in HGF cell proliferation of 6% when incubated with SEQ ID NO: 500.

[0345] FIG. 67 shows an increase in HGF cell proliferation of 125% when incubated with SEQ ID NO: 503.

[0346] FIG. 68 shows an increase in HGF cell proliferation of 121% when incubated with SEQ ID NO: 474.

[0347] FIG. 69 shows an increase in HGF cell proliferation of 119% when incubated with SEQ ID NO: 504.

[0348] FIG. 70 shows an increase in HGF cell proliferation of 119% when incubated with SEQ ID NO: 114.

[0349] FIG. 71 shows an increase in HGF cell proliferation of 118% when incubated with SEQ ID NO: 505.

[0350] FIG. 72 shows an increase in HGF cell proliferation of 113% when incubated with SEQ ID NO: 482.

[0351] FIG. 73 shows an increase in HGF cell proliferation of 106% when incubated with SEQ ID NO: 479.

[0352] FIG. 74 shows an increase in HGF cell proliferation of 81% when incubated with SEQ ID NO: 477.

[0353] FIG. 75 shows an increase in HGF cell proliferation of 73% when incubated with SEQ ID NO: 410.

[0354] FIG. 76 shows an increase in HGF cell proliferation of 69% when incubated with SEQ ID NO: 475.

[0355] FIG. 77 shows an increase in HGF cell proliferation of 58% when incubated with SEQ ID NO: 497.

[0356] FIG. 78 shows an increase in HGF cell proliferation of 102% when incubated with SEQ ID NO: 480.

[0357] FIG. 79 shows an increase in HGF cell proliferation of 100% when incubated with SEQ ID NO: 463.

[0358] FIG. 80 shows an increase in HGF cell proliferation of 96% when incubated with SEQ ID NO: 465.

[0359] FIG. 81 shows an increase in HGF cell proliferation of 90% when incubated with SEQ ID NO: 467.

[0360] FIG. 82 shows an increase in HGF cell proliferation of 85% when incubated with SEQ ID NO: 461.

[0361] FIG. 83 shows an increase in HGF cell proliferation of 83% when incubated with SEQ ID NO: 341.

[0362] FIG. 84 shows an increase in HGF cell proliferation of 82% when incubated with SEQ ID NO: 468.

[0363] FIG. 85 shows an increase in HGF cell proliferation of 81% when incubated with SEQ ID NO: 485.

[0364] FIG. 86 shows an increase in HGF cell proliferation of 81% when incubated with SEQ ID NO: 496.

[0365] FIG. 87 shows an increase in HGF cell proliferation of 80% when incubated with SEQ ID NO: 146.

[0366] FIG. 88 shows an increase in HGF cell proliferation of 76% when incubated with SEQ ID NO: 478.

[0367] FIG. 89 shows an increase in HGF cell proliferation of 76% when incubated with SEQ ID NO: 452.

[0368] FIG. 90 shows an increase in HGF cell proliferation of 68% when incubated with SEQ ID NO: 495.

[0369] FIG. 91 shows an increase in HGF cell proliferation of 51% when incubated with SEQ ID NO: 403.

[0370] FIG. 92 shows an increase in HGF cell proliferation of 47% when incubated with SEQ ID NO: 455.

[0371] FIG. 93 shows an increase in HGF cell proliferation of 47% when incubated with SEQ ID NO: 270.

[0372] FIG. 94 shows an increase in HGF cell proliferation of 43% when incubated with SEQ ID NO: 501.

[0373] FIG. 95 shows an increase in HGF cell proliferation of 41% when incubated with SEQ ID NO: 473.

[0374] FIG. 97 shows an increase in HGF cell proliferation of 38% when incubated with SEQ ID NO: 471.

[0375] FIG. 98 shows an increase in HGF cell proliferation of 38% when incubated with SEQ ID NO: 460.

[0376] FIG. 99 shows an increase in HGF cell proliferation of 26% when incubated with SEQ ID NO: 93.

[0377] FIG. 100 shows an increase in HGF cell proliferation of 15% when incubated with SEQ ID NO: 462.

Example 2Collagen Production Assay

[0378] Hydroxyproline in tissue preparations is a direct measure of the amount of collagen present. FIRELISA Human Hydroxyproline ELISA kit assay is designed to measure hydroxyproline in tissue or peptide compositions.

[0379] Human Dermal Fibroblasts (HDF Sigma 10605a) were seeded in 24 well plates at 50,000 cells per well in DMEM containing 10% fetal calf serum (FCS), 1% Pen/strep, 1% L-glutamine and allowed to adhere for 24 h.

[0380] Following the initial 24 h incubation the cells were incubated with 5 g/ml, 1 g/ml or 0.1 g/ml synthetic peptide for 96 h respectively.

[0381] After treatment the cells were lysed using 4 freeze thaw cycles in liquid nitrogen. The lysed cells were centrifuged and 50 l/ml of each supernatant was assayed using the FIRELISA Human Hydroxyproline ELISA kit. All steps were carried out according to the manufacturer's instructions.

[0382] Results were calculated as a percentage of the untreated control. An increase in optical density reading indicates an increase collagen content.

[0383] The results are shown in FIGS. 102, 104, 106 and 109

Example 3Elastin Production Assay

[0384] Elastin is a highly elastic protein in connective tissue and allows many tissues in the body to resume their shape after stretching or contracting. FIRELISA Human Elastin ELISA kit assay is designed to measure Elastin in tissue or protein/peptide compositions.

[0385] Human Dermal Fibroblasts (HDF) were seeded in 24 well plates at 50,000 cells per well in DMEM containing 10% fetal calf serum (FCS), 1% Pen/strep, 1% L-glutamine and allowed to adhere for 24 h.

[0386] Following the initial 24 h incubation the cells were incubated with 5 g/ml, 1 g/ml or 0.1 g/ml synthetic peptide for 96 h respectively.

[0387] After treatment the cells were lysed using 4 freeze thaw cycles in liquid nitrogen. The lysed cells were centrifuged and 50 l/ml of each supernatant was assayed using the FIRELISA Human Elastin ELISA kit. All steps were carried out according to the manufacturer's instructions.

[0388] Results were calculated as a percentage of the untreated control. An increase in optical density reading indicates an increase collagen content.

[0389] The results are shown in FIGS. 101, 103, 105, 107, 108 and 109.

Example 4Elastin and Cell Proliferation Assays

TABLE-US-00010 TABLE 2 Test items. Orange bands correspond to samples dissolved into DMSO 0.3% instead of water. Intertek Item Denomination Concentration Provider Nature reference Solubility Storage Peptide 1 E_280_PJ 20 M Nuritas Peptide 14-CHL- Water 80 C. 0723-01 Peptide 2 I_222two_IN 20 M Nuritas Peptide 14-CHL- Water Ambient 0723-02 Peptide 3 E_134_two_IN 20 M Nuritas Peptide 14-CHL- Water 80 C. 0723-03 Peptide 4 E_30two_IN 20 M Nuritas Peptide 14-CHL- Water 80 C. 0723-04 Peptide 5 E_121two_IN 20 M Nuritas Peptide 14-CHL- Water 80 C. 0723-05 Peptide 6 I_10two_IN 20 M Nuritas Peptide 14-CHL- DMSO 80 C. 0723-06 0.3% Peptide 7 I_41two_IN 20 M Nuritas Peptide 14-CHL- DMSO 80 C. 0723-07 0.3% Peptide 8 E_41_PJ 10 M* Nuritas Peptide 14-CHL- Water 80 C. 0723-08 Composition E_2_IN 500 g/mL Nuritas Composition 14-CHL- Water 80 C. P9 of peptides 0723-09 Composition I_2_IN 500 g/mL Nuritas Composition 14-CHL- Water 80 C. P10 of peptides 0723-10

Equipment

[0390] Incubator, Flow Laminar Chamber, Sterile Polished Plastic Rod, Pipettor, Maintenance medium, Plate 6 well, Plate 24 well.

Reagents

[0391] MTT, PBS, SDS, Formaldehyde, Xylene, Ethanol absolute, Dulbecco's phosphate-buffered saline (DPBS), Metal Enhanced DAB substrate kit, ABC peroxidase staining kit, Citric acid, Sodium hydroxide 2N, Hydrogen peroxide 30%, Anti-Filaggrin, Anti-rabbit IgG-Biotin, Tween 20.

Test System

[0392] Nature: Human skin tissue 5 mm diameter

[0393] Batch number: EXP004050B009 and EXP004050B011

[0394] Provider: Laboratoire Biopredic International-8-18 rue Jean Pecker-35000 Rennes-France. Tel: +33 (0) 2.99.14.36.14-Fax: +33 (0) 2.99.54.44.72.

[0395] Certificates of analysis are present in Annex 1.

[0396] Two batches are used for the assay. Batch EXP004050B005 is used for experiment day 1, and Batch EXP004050B006 is used for experiment day 5.

Maintenance Medium

[0397] Maintenance Medium: Batch no: MIL 218 C Provider: Laboratoire Biopredic International-8-18 rue Jean Pecker-35000 Rennes-France.

Peptides Tested

TABLE-US-00011 P1: SEQIDNO:283 P2: SEQIDNO:246 P3: SEQIDNO:284 P4: RPYYSNAPQEIF P5: VLLEQQEQEPQH P6: SEQIDNO:245 P7: QQYGIAASPFLQSAA P8: SEQIDNO:42

Compositions Tested

[0398] P9 (14-CHL-0723-09) is the Pea composition (SEQ ID NOs: 50, 85, 74, 140, 82, 136, 189, 77, 169, 149, 171, 178, 143, 127, 190, 141, 147, 133, 186, 125, 122, 119, 87, 90, 86, 89, 138, 129, 123, 120, 117, 113, 110, 121, 105, 98, 55, 161, 19, 317, 135, 130, 146, 177, 160, 170, 188, 83, 78, 36, 96, 159, 26, 330, 168, 148, 184, 151, 151, 165, 114, 284)

[0399] P10 (14-CHL-0723-010) is the Rice composition (SEQ ID NOs: 245, 246, 263, 250, 257, 259, 276, 255, 251, 264, 256, 266, 274, 270, 269, 356, 245, 380, 262, 258, 356, 218, 252, 358, 271, 253, 344, 275, 272, 226, 224, 220, 248, 261, 265, 373, 375, 247, 249, 363, 273, 343, 273, 362)

Application Method

[0400] Skin explants were prepared from abdominal plastic surgery. Some explants were delipidated with alcohol to obtain a dehydrated skin.

[0401] These explants were maintained in maintenance medium supplied by the provider Bioprdic International for 5 days. Test items are applied twice per day with 5 L per explant.

[0402] At the end of the test, viabilities controls are realized with the MTT on two explants, the third explant is fixed in the formaldehyde 4% for histology and cell staining.

[0403] For each time of analysis (D1 and D5), histologies on delipidated explants, treated explants with test items, the DMSO 0.3% control and water control, are performed.

[0404] After receipt in the laboratory, each skin explant in the maintenance medium is delipidated with 5 L alcohol during 3 hours.

[0405] After 3 hours, all skin explants are treated two per day with test items, and they are incubated at 37 C.+/2 C., 5% CO2 for 1 day or 5 days.

[0406] Integrity of the system is realized at day 1 and day 5 with a viability control with MTT.

Immunostaining

[0407] Histology is realized by the laboratory Gredeco and the immunostaining to elastin and Ki67 are realized by the same laboratory. Immunostaining to filaggrin is realized by the laboratory

Intertek.

[0408] The detection of elastin (rabbit monoclonal antibody, clone P15502, LSBio) is performed using an immunoperoxidase technique two layers (ABC kit, Vector Laboratories) and revealed by AEC (3-amino-9-thylcarbazole). The immunohistochemical staining intensity in the elastic fibers is evaluated using a semi-quantitative histological score.

[0409] Epithelial proliferation was analyzed by immunohistochemistry using anti-Ki67 antibody. Immunodetection was performed using an indirect immunoperoxidase technique three layers, amplified (DAKO kit) and revealed by AEC (3-Amino-9-ethylcarbazole). Counting the number of labeled cells (keratinocytes of the basal layer of the epidermis) is performed and provides the total number of basal cells to calculate the % of labeled cells.

[0410] The specific staining of filaggrin is performed with an immunoperoxidase staining (ABC kit, Fisher). The intensity of immunohistochemical marker in the epidermis is evaluated relative to the negative control of the solvent (Water or DMSO 0.3%).

C: Results

Viability Control

[0411] The integrity control and the viability control are present in FIG. 1. These controls do allow to validate the assay system. The viability is >50% for test items, and they do not show a cytotoxicity according to the test.

Immunostaining

Elastin Expression

[0412] The elastic fibers of the dermis were revealed by staining with the catechin and morphometrically quantified by analysis by computer-assisted image. The percentage area taken up by elastic fibers in the dermis was calculated in the dermis and the average superficial dermis. Results are presented in FIGS. 101, 105, 107, and 108.

TABLE-US-00012 TABLE 3 Morphometric quantification of elastic fibers in the superficial dermis (%) and middle dermis. Orange bands correspond to samples dissolved into DMSO 0.3% instead of water. Morphometric Morphometric quantification quantification of elastic fibers of elastic fibers in the superficial in the middle dermis (%) dermis (%) Conditions D1 D5 D1 D5 Dehydrated with alcohol 4.31 4.9 5 5.83 and hydrated with water Dehydrated 2.38 7.26 4.39 9.59 EGF (Epidermal Growth 3.64 5.61 5.68 6.61 Factor) 10 ng/mL Dehydrated with alcohol 3.76 7.24 6 10.36 and hydrated with DMSO 0.3% 0723.01 4.45 10.21 7.59 10.17 0723.02 6.09 7.59 11.75 9.08 0723.03 3 11.68 4.9 9 0723.04 3.28 8.94 5.22 9 0723.05 6.34 6.26 8.8 6.61 0723.06 3.8 4.03 4.54 8.67 0723.07 4 5.15 6.46 5.33 0723.08 2.7 5.32 3.52 7.27 0723.09 3.26 8.26 5.75 7.92 0723.10 4.1 8 5.73 8.34

[0413] Under the experimental conditions of the study, 0723-1 and 0723-3 samples show an increase by twice of elastic fibers in the superficial dermis compared to control water (Figure), and an increase in the middle dermis compared to the water control at D5.

[0414] The 0723-2 sample shows an increase doubled in the middle dermis at day 1 compared to control water and an increase at day 5.

Ki67 Expression

[0415] The results of the immunohistochemical analysis of Ki67 are reported in Table 4 and expressed as % of labelled at the basal layer of the epidermis. The FIG. 115 shows the percentage of Ki 67 cells compared to negative controls (water or DMSO). Immunohistochemical analysis of mitotic activity is shown in annex 4 with a reminder of the average for each analysed conditions.

TABLE-US-00013 TABLE 4 % of Ki67 positive cells in the basal layer of the epidermis. Orange bands correspond to samples dissolved into DMSO 0.3% instead of water. Conditions D1 D5 Dehydrated with alcohol and 19.09 3.53 hydrated with water Dehydrated 17.05 1.76 EGF (Epidermal Growth Factor) 10 ng/mL 25.11 4.2 Dehydrated with alcohol and hydrated with 17.2 2.61 DMSO 0.3% 0723.01 18.57 3.92 0723.02 19.61 6.73 0723.03 22.01 10.04 0723.04 14.97 11.36 0723.05 9.48 3.08 0723.06 31.97 5.04 0723.07 22.22 5.26 0723.08 27.83 5.72 0723.09 31.02 2.4 0723.10 31.94 3.57

[0416] Under the experimental conditions of the study, test item 0723-06, 0723-08, 0723-09 and 0723-010 show an increase in the number of mitotic cells compared to EGF at day 1. A decrease in the mitotic index was observed on day 5 compared to day 1 for all analysed conditions.

[0417] The decrease in this cell staining on day 5 is caused by the model. Indeed, after approximately 3 days cell turnover is exhausted on this model.

[0418] The invention is not limited to the embodiments hereinbefore described which may be varied in construction and detail without departing from the spirit of the invention.

TABLE-US-00014 SEQUENCES PROTEIN:P13918-2-PEA MAATTMKASFPLLMLMGISFLASVCVSSRSDPQNPFIFKSNKFQTLFENENGHIRLLQKFDQRSKIFENLQNYRLLEYKSKPHTIFLPQHTDADYI LVVLSGKAILTVLKPDDRNSFNLERGDTIKLPAGTIAYLVNRDDNEELRVLDLAIPVNRPGQLQSFLLSGNQNQQNYLSGFSKNILEASFNTDYEE IEKVLLEEHEKETQHRRSLKDKRQQSQEENVIVKLSRGQIEELSKNAKSTSKKSVSSESEPFNLRSRGPIYSNEFGKFFEITPEKNPQLQDLDIFVNS VEIKEGSLLLPHYNSRAIVIVTVNEGKGDFELVGQRNENQQEQRKEDDEEEEQGEEEINKQVQNYKAKLSSGDVFVIPAGHPVAVKASSNLDLL GFGINAENNQRNFLAGDEDNVISQIQRPVKELAFPGSAQEVDRILENQKQSHFADAQPQQRERGSRETRDRLSSV[SEQID1] PEPTIDE:QNYLSGFSKNILE[SEQID15] PEPTIDE:TIKLPAGTIAYLVNRDDNEE[SEQID16] PEPTIDE:LAIPVNRPGQLQSFL[SEQID17] PEPTIDE:AIPVNRPGQLQ[SEQID18] PEPTIDE:PAGHPVAVK[SEQID19] PEPTIDE:VQNYKAKLSSGDVFVIPAG[SEQID20] PEPTIDE:NNQRNFLAGDEDNVISQIQRPVKE[SEQID21] PEPTIDE:INKQVQNYKAKLSSGDVFVIPAG[SEQID22] PEPTIDE:LAIPVNRPGQ[SEQID23] PEPTIDE:NFLAGDEDNVISQIQRPVKE[SEQID24] PEPTIDE:DLAIPVNRPGQLQSF[SEQID25] PEPTIDE:VIPAGHPVAVK[SEQID26] PEPTIDE:DTIKLPAGTIAYLVNRDDNEE[SEQID27] PEPTIDE:LAIPVNRPGQLQSF[SEQID28] PEPTIDE:KQVQNYKAKLSSGDVFVIPAG[SEQID29] PEPTIDE:RGDTIKLPAGTIAYLVNRDDNEE[SEQID30] PEPTIDE:FLAGDEDNVISQIQRPVKE[SEQID31] PEPTIDE:LAIPVNRPGQLQS[SEQID32] PEPTIDE:VLDLAIPVNRPGQLQ[SEQID33] PEPTIDE:DLAIPVNRPGQLQ[SEQID34] PEPTIDE:VFVIPAGHPVAVK[SEQID35] PEPTIDE:TIFLPQHTDADYILVVLSGK[SEQID36] PEPTIDE:NQRNFLAGDEDNVISQIQRPVKE[SEQID37] PEPTIDE:LAIPVNRPGQLQ[SEQID38] PEPTIDE:HPVAVKASSNLDLLGFG[SEQID39] PEPTIDE:LAIPVNRPGQL[SEQID40] PEPTIDE:DLAIPVNRPGQL[SEQID41] PEPTIDE:SKPHTIFLPQHTDADYILVVLSGK[SEQID42] PEPTIDE:FVIPAGHPVAVK[SEQID43] PEPTIDE:DLAIPVNRPGQLQS[SEQID44] PEPTIDE:SGDVFVIPAGHPVAVKASSNLD[SEQID45] PEPTIDE:AIPVNRPGQLQSF[SEQID46] PEPTIDE:ELAFPGSAQEVDR[SEQID47] PEPTIDE:LAIPVNRPGQLQSFLLSG[SEQID48] PEPTIDE:VFVIPAGHPVAVKASSNLDLLGFG[SEQID49] PEPTIDE:AGHPVAVK[SEQID50] PEPTIDE:HPVAVKASSNLDLLGFGINAE[SEQID51] PEPTIDE:LAIPVNRPGQLQSFLLSGNQNQ[SEQID52] PEPTIDE:SGDVFVIPAG[SEQID53] PEPTIDE:GSLLLPHYNSRAIVIVTVNE[SEQID54] PEPTIDE:NFLAGDEDNVISQIQRPVK[SEQID55] PEPTIDE:SGDVFVIPAGHPVA[SEQID56] PEPTIDE:GSLLLPHYNSRAIVIV[SEQID57] PEPTIDE:RGDTIKLPAGTIAYLVNRDD[SEQID58] PEPTIDE:SGDVFVIPAGHPVAVK[SEQID59] PEPTIDE:LSSGDVFVIPAGHPVAVK[SEQID60] PEPTIDE:LDLAIPVNRPGQL[SEQID61] PEPTIDE:AIPVNRPGQL[SEQID62] PEPTIDE:LAIPVNRPGQLQSFLL[SEQID63] PEPTIDE:PHTIFLPQHTDADYILVVLSGK[SEQID64] PEPTIDE:VFVIPAGHPVAVKASSNLD[SEQID65] PEPTIDE:LAIPVNRPGQLQSFLLS[SEQID66] PEPTIDE:VLDLAIPVNRPGQLQSF[SEQID67] PEPTIDE:AIPVNRPGQLQS[SEQID68] PEPTIDE:DTIKLPAGTIAYLVNRDDNE[SEQID69] PEPTIDE:NYKAKLSSGDVFVIPAG[SEQID70] PEPTIDE:GKAILTVLKPDDRNSFNLE[SEQID71] PEPTIDE:YKSKPHTIFLPQHTDAD[SEQID72] PEPTIDE:ASSNLDLLGFG[SEQID73] PEPTIDE:DEEEEQGEEEINK[SEQID74] PEPTIDE:YKSKPHTIFLPQHTD[SEQID75] PEPTIDE:VLDLAIPVNR[SEQID76] PEPTIDE:FFEITPEKNPQLQDLDIFVNSVEIK[SEQID77] PEPTIDE:TIFLPQHTDADYIL[SEQID78] PEPTIDE:SFLLSGNQNQQNYLSG[SEQID79] PEPTIDE:SFLLSGNQNQQNYLSGFS[SEQID80] PEPTIDE:NQQEQRKEDDEEEEQGEEE[SEQID81] PEPTIDE:EEQGEEEINK[SEQID82] PEPTIDE:SRGPIYSNE[SEQID83] PEPTIDE:EDDEEEEQGEEEINK[SEQID84] PEPTIDE:DDEEEEQGEEEINK[SEQID85] PEPTIDE:KEDDEEEEQGEEEIN[SEQID86] PEPTIDE:KEDDEEEEQGEE[SEQID87] PEPTIDE:QRKEDDEEEEQGEEE[SEQID88] PEPTIDE:KEDDEEEEQGEEEINK[SEQID89] PEPTIDE:KEDDEEEEQGEEE[SEQID90] PROTEIN:Q9M3X6-3-PEA MATTIKSRFPLLLLLGIIFLASVVCVTYANYDEGSEPRVPAQRERGRQEGEKEEKRHGEWRPSYEKEEDEEEGQRERGRQEGEKEEKRHGEWR PSYEKQEDEEEKQKYRYQREKEDEEEKQKYQYQREKKEQKEVQPGRERWEREEDEEQVDEEWRGSQRREDPEERARLRHREERTKRDRRHQ REGEEEERSSESQERRNPFLFKSNKFLTLFENENGHIRLLQRFDKRSDLFENLQNYRLVEYRAKPHTIFLPQHIDADLILVVLSGKAILTVLSPNDR NSYNLERGDTIKLPAGTTSYLVNQDDEEDLRLVDLVIPVNGPGKFEAFDLAKNKNQYLRGFSKNILEASYNTRYETIEKVLLEEQEKDRKRRQQG EETDAIVKVSREQIEELKKLAKSSSKKSLPSEFEPINLRSHKPEYSNKFGKLFEITPEKKYPQLQDLDLFVSCVEINEGALMLPHYNSRAIVVLLVNEG KGNLELLGLKNEQQEREDRKERNNEVQRYEARLSPGDVVIIPAGHPVAITASSNLNLLGFGINAENNERNFLSGSDDNVISQIENPVKELTFPGS VQEINRLIKNQKQSHFANAEPEQKEQGSQGKRSPLSSILGTFY[SEQID2] PEPTIDE:HPVAITASSNLNLLG[SEQID91] PEPTIDE:ASSNLNLLGFG[SEQID92] PEPTIDE:ITASSNLNLLGFG[SEQID93] PEPTIDE:ITASSNLNLLGFGINAE[SEQID94] PEPTIDE:SSNLNLLGFG[SEQID95] PEPTIDE:VDLVIPVNGPGKF[SEQID96] PEPTIDE:LVIPVNGPGKFE[SEQID97] PEPTIDE:LVIPVNGPGKFEA[SEQID98] PEPTIDE:LRLVDLVIPVNGPGKFE[SEQID99] PEPTIDE:YRAKPHTIFLPQHIDAD[SEQID100] PEPTIDE:HPVAITASSNLNLLGFGINAE[SEQID101] PEPTIDE:SNLNLLGFG[SEQID102] PEPTIDE:HPVAITASSNLNLLGFGINAENNE[SEQID103] PEPTIDE:LVDLVIPVNGPGKFE[SEQID104] PEPTIDE:LVIPVNGPGKF[SEQID105] PEPTIDE:TIKLPAGTTSYLVNQDDE[SEQID106] PEPTIDE:DLRLVDLVIPVNGPGKFE[SEQID107] PEPTIDE:EDLRLVDLVIPVNGPGKFE[SEQID108] PEPTIDE:HPVAITASSNLNLLGFG[SEQID109] PEPTIDE:LVDLVIPVNGPGKFEAFDLAK[SEQID110] PEPTIDE:DNVISQIENPVKE[SEQID111] PEPTIDE:VVIIPAGHPVAITASSNLNLLGFG[SEQID112] PEPTIDE:LVDLVIPVNGPGKFEAF[SEQID113] PEPTIDE:YPQLQDLDL[SEQID114]] PEPTIDE:VIPVNGPGKF[SEQID115 PEPTIDE:SKKSLPSE[SEQID116] PEPTIDE:LPQHIDADLILVVLSGK[SEQID117] PEPTIDE:RGDTIKLPAGTTSYLVNQD[SEQID118] PEPTIDE:IPVNGPGKF[SEQID119] PEPTIDE:LPQHIDADL[SEQID120] PEPTIDE:LVIPVNGPGK[SEQID121] PEPTIDE:IFLPQHIDAD[SEQID122] PEPTIDE:LPQHIDAD[SEQID123] PEPTIDE:VIPVNGPGK[SEQID124] PEPTIDE:IFLPQHIDA[SEQID125] PEPTIDE:TIKLPAGTTSYLVNQDDEE[SEQID126] PEPTIDE:HGEWRPSYEKEEDEEEGQRER[SEQID127] PEPTIDE:EKRHGEWRPSYEKEEDEEEGQRE[SEQID128] PEPTIDE:LPAGTTSYLVNQDDEEDLR[SEQID129] PEPTIDE:PSYEKEEDEEEGQRER[SEQID130] PEPTIDE:EKRHGEWRPSYE[SEQID131] PEPTIDE:TIKLPAGTTSYLVNQDDEED[SEQID132] PEPTIDE:HGEWRPSYEKQEDEEEK[SEQID133] PEPTIDE:EWRPSYEKEEDEEE[SEQID134] PEPTIDE:PSYEKEEDEEEGQR[SEQID135] PEPTIDE:EKEEDEEEGQR[SEQID136] PEPTIDE:EWRPSYEKEEDEEEGQRE[SEQID137] PEPTIDE:KEEDEEEGQR[SEQID138] PEPTIDE:VQPGRERWEREEDEEQVDE[SEQID139] PEPTIDE:DVVIIPAGHPVA[SEQID140] PEPTIDE:HGEWRPSYEKQEDE[SEQID141] PEPTIDE:EEDEEEGQR[SEQID142] PEPTIDE:HGEWRPSYEKEEDEEEGQR[SEQID143] PEPTIDE:EEWRGSQRREDPEE[SEQID144] PEPTIDE:REEDEEQVDEEWRGSQRREDPEE[SEQID145] PEPTIDE:RHGEWRPSY[SEQID146] PEPTIDE:HGEWRPSYEKQEDEE[SEQID147] PEPTIDE:VVIIPAGHPVA[SEQID148] PEPTIDE:HGEWRPSYE[SEQID149] PEPTIDE:KEEDEEEGQRER[SEQID150] PEPTIDE:VVIIPAGHPVAIT[SEQID151] PEPTIDE:EKRHGEWRPSYEKEEDE[SEQID152] PEPTIDE:QVDEEWRGSQRREDPEE[SEQID153] PEPTIDE:GDTIKLPAGTTSYLVNQDDEEDLR[SEQID154] PEPTIDE:GSEPRVPAQRE[SEQID155] PEPTIDE:EEKRHGEWRPSYEKE[SEQID156] PEPTIDE:EWRPSYEKEEDEE[SEQID157] PEPTIDE:NYDEGSEPRVPAQRE[SEQID158] PEPTIDE:VIIPAGHPVAIT[SEQID159] PEPTIDE:RHGEWRPSYEK[SEQID160] PEPTIDE:NYDEGSEPR[SEQID161] PEPTIDE:WRPSYEKEEDEE[SEQID162] PEPTIDE:WRPSYEKQEDEEE[SEQID163] PEPTIDE:EKRHGEWRPSYEKQEDEEE[SEQID164] PEPTIDE:VVIIPAGHPVAITA[SEQID165] PEPTIDE:KRHGEWRPSYE[SEQID166] PEPTIDE:GSDDNVISQIENPVKE[SEQID167] PEPTIDE:VVIIPAGHPV[SEQID168] PEPTIDE:HGEWRPSY[SEQID169] PEPTIDE:RPSYEKEEDEEEGQR[SEQID170] PEPTIDE:HGEWRPSYEK[SEQID171] PEPTIDE:KRHGEWRPSYEKEE[SEQID172] PEPTIDE:VVIIPAGHPVAITAS[SEQID173] PEPTIDE:RGDTIKLPAGTTSYLVNQDDEED[SEQID174] PEPTIDE:KRHGEWRPSYEKQEDEEE[SEQID175] PEPTIDE:DEEQVDEEWRGSQRREDPEE[SEQID176] PEPTIDE:RHGEWRPSYE[SEQID177] PEPTIDE:HGEWRPSYEKE[SEQID178] PEPTIDE:KRHGEWRPSYEKEEDEEE[SEQID179] PEPTIDE:EKRHGEWRPSYEKEEDEEE[SEQID180] PEPTIDE:TIKLPAGTTSYLVNQDDEEDLRLVD[SEQID181] PEPTIDE:WRPSYEKEEDEEEGQRE[SEQID182] PEPTIDE:KRHGEWRPSYEKEEDEE[SEQID183] PEPTIDE:VVIIPAGHPVAI[SEQID184] PEPTIDE:EWRGSQRREDPEE[SEQID185] PEPTIDE:HGEWRPSYEKQEDEEEKQK[SEQID186] PEPTIDE:SGSDDNVISQIENPVKE[SEQID187] PEPTIDE:RPSYEKEEDEEEGQRER[SEQID188] PEPTIDE:EKEEDEEEGQRER[SEQID189] PEPTIDE:HGEWRPSYEKQ[SEQID190] PEPTIDE:WRPSYEKEEDEEE[SEQID191] PEPTIDE:LAKNKNQYLRGFS[SEQID192] PEPTIDE:NKNQYLRGFS[SEQID193] PEPTIDE:LRGFSKNILE[SEQID194] PEPTIDE:LAKNKNQYLRGFSKN[SEQID195] PEPTIDE:TVLSPNDRNSY[SEQID196] PEPTIDE:QYLRGFSKNILE[SEQID197] PEPTIDE:GKAILTVLSPNDRNSYNLE[SEQID198] PEPTIDE:RGFSKNILE[SEQID199] PEPTIDE:NKNQYLRGFSKNILE[SEQID200] PEPTIDE:ASSNLNLLGFGINAE[SEQID201] PEPTIDE:ASSNLNLLGF[SEQID202] PEPTIDE:LAKNKNQYLRGFSK[SEQID203] PEPTIDE:RGDTIKLPAGTTSYLVNQDDEE[SEQID204] PEPTIDE:ARLSPGDVVIIPAGHPVAITASSN[SEQID205] PEPTIDE:VQRYEARLSPGD[SEQID206] PEPTIDE:ARLSPGDVVIIPAGHPVAIT[SEQID207] PEPTIDE:RGDTIKLPAGTTSYLVNQDDE[SEQID208] PEPTIDE:ARLSPGDVVIIPAGHPVA[SEQID209] PEPTIDE:GALMLPHYNSRAIVVLLVNE[SEQID210] PEPTIDE:ARLSPGDVVIIPAGHPVAITASS[SEQID211] PEPTIDE:LSPGDVVIIPAGHPVAITASSNLNLLGFGINAENNER[SEQID212] PEPTIDE:ARLSPGDVVIIPAGHPVAITAS[SEQID213] PEPTIDE:LSPGDVVIIPAGHPVAITASSNL[SEQID214] PEPTIDE:ARLSPGDVVIIPAGHPVAITA[SEQID215] PROTEIN:Q0DEV5-5-RICE MSALTTSQLATSATGFGIADRSAPSSLLRHGFQGLKPRSPAGGDATSLSVTTSARATPKQQRSVQRGSRRFPSVVVYATGAGMNVVFVGAEM APWSKTGGLGDVLGGLPPAMAANGHRVMVISPRYDQYKDAWDTSVVAEIKVADRYERVRFFHCYKRGVDRVFIDHPSFLEKVWGKTGEKIY GPDTGVDYKDNQMRFSLLCQAALEAPRILNLNNNPYFKGTYGEDVVFVCNDWHTGPLASYLKNNYQPNGIYRNAKVAFCIHNISYQGRFAFE DYPELNLSERFRSSFDFIDGYDTPVEGRKINWMKAGILEADRVLTVSPYYAEELISGIARGCELDNIMRLTGITGIVNGMDVSEWDPSKDKYITA KYDATTAIEAKALNKEALQAEAGLPVDRKIPLIAFIGRLEEQKGPDVMAAAIPELMQEDVQIVLLGTGKKKFEKLLKSMEEKYPGKVRAVVKFNA PLAHLIMAGADVLAVPSRFEPCGLIQLQGMRYGTPCACASTGGLVDTVIEGKTGFHMGRLSVDCKVVEPSDVKKVAATLKRAIKVVGTPAYEE MVRNCMNQDLSWKGPAKNWENVLLGLGVAGSAPGIEGDEIAPLAKENVAAP[SEQID3] PEPTIDE:NWENVLLGLGVAGSAPGIEGDEIAPLAK[SEQID216] PEPTIDE:YDQYKDAWDTSVVAEIK[SEQID217] PEPTIDE:SSFDFIDGYDTPVEGR[SEQID218] PEPTIDE:GPDTGVDYKDNQM[SEQID219] PEPTIDE:ILNLNNNPYFK[SEQID220] PEPTIDE:VVGTPAYEE[SEQID221] PEPTIDE:IDGYDTPVEGR[SEQID222] PEPTIDE:VVGTPAYE[SEQID223] PEPTIDE:IYGPDTGVDYK[SEQID224] PEPTIDE:VAGSAPGIEGDE[SEQID225] PEPTIDE:IYGPDTGVDYKDNQMR[SEQID226] PEPTIDE:VVGTPAYEEMVR[SEQID227] PEPTIDE:DFIDGYDTPVEGR[SEQID228] PEPTIDE:LGLGVAGSAPGIEGDEIAPLAK[SEQID229] PEPTIDE:FNAPLAHLIMAGADVLAVPSR[SEQID230] PEPTIDE:LGLGVAGSAPGIEGDE[SEQID231] PEPTIDE:LGLGVAGSAPGIEGDEIAPL[SEQID232] PEPTIDE:VLTVSPYYAEELISGIAR[SEQID233] PEPTIDE:EALQAEAGLPVDR[SEQID234] PEPTIDE:LGLGVAGSAPGIEGD[SEQID235] PEPTIDE:IMAGADVLAVPSR[SEQID236] PEPTIDE:GLGVAGSAPGIEGDE[SEQID237] PEPTIDE:EALQAEAGLPVDRK[SEQID238] PEPTIDE:TGGLGDVLGGLPPAMAANGHR[SEQID239] PEPTIDE:LEEQKGPDVMA[SEQID240] PEPTIDE:LGVAGSAPGIEGDEIAPLAK[SEQID241] PEPTIDE:GLGVAGSAPGIEGDEIAPLAK[SEQID242] PEPTIDE:TGGLGDVLGGLPPAM[SEQID243] PEPTIDE:NVLLGLGVAGSAPGIEGDE[SEQID244] PROTEIN:P14323-6-RICE MASSVFSRFSIYFCVLLLCHGSMAQLFNPSTNPWHSPRQGSFRECRFDRLQAFEPLRKVRSEAGVTEYFDEKNELFQCTGTFVIRRVIQPQGLL VPRYTNIPGVVYIIQGRGSMGLTFPGCPATYQQQFQQFSSQGQSQSQKFRDEHQKIHQFRQGDIVALPAGVAHWFYNDGDAPIVAVYVYDV NNNANQLEPRQKEFLLAGNNNRAQQQQVYGSSIEQHSGQNIFSGFGVEMLSEALGINAVAAKRLQSQNDQRGEIIHVKNGLQLLKPTLTQQ QEQAQAQDQYQQVQYSERQQTSSRWNGLEENFCTIKVRVNIENPSRADSYNPRAGRITSVNSQKFPILNLIQMSATRVNLYQNAILSPFWNV NAHSLVYMIQGRSRVQVVSNFGKTVFDGVLRPGQLLIIPQHYAVLKKAEREGCQYIAIKTNANAFVSHLAGKNSVFRALPVDVVANAYRISRE QARSLKNNRGEEHGAFTPRFQQQYYPGLSNESESETSE[SEQID4] PEPTIDE:TVFDGVLRPGQL[SEQID245] PEPTIDE:RLQSQNDQRGEIIHVK[SEQID246] PROTEIN:P29835-5-RICE MASKVVFFAAALMAAMVAISGAQLSESEMRFRDRQCQREVQDSPLDACRQVLDRQLTGRERFQPMFRRPGALGLRMQCCQQLQDVSRE CRCAAIRRMVRSYEESMPMPLEQGWSSSSSEYYGGEGSSSEQGYYGEGSSEEGYYGEQQQQPGMTRVRLTRARQYAAQLPSMCRVEPQQC SIFAAGQY[SEQID5] PEPTIDE:EGYYGEQQQQPGMTR[SEQID247] PEPTIDE:GYYGEQQQQPGMTR[SEQID248] PEPTIDE:EEGYYGEQQQQPGMTR[SEQID249] PEPTIDE:YYGGEGSSSEQGYYGEGSSE[SEQID250] PEPTIDE:YGGEGSSSEQGYYGEGSSE[SEQID251] PEPTIDE:SSEEGYYGEQQQQPGMTR[SEQID252] PEPTIDE:SEEGYYGEQQQQPGMTR[SEQID253] PEPTIDE:QGYYGEGSSEE[SEQID254] PEPTIDE:YGGEGSSSEQGYYGEGSSEEGY[SEQID255] PEPTIDE:YGEQQQQPGMTR[SEQID256] PEPTIDE:YYGEQQQQPGMTR[SEQID257] PEPTIDE:SYEESMPMPLEQGWSSSSSE[SEQID258] PEPTIDE:YYGEGSSEEGYYGEQQQQPGMTR[SEQID259] PEPTIDE:QQQQPGMTRV[SEQID260] PEPTIDE:GEQQQQPGMTR[SEQID261] PEPTIDE:SYEESMPMPLEQGWSSSSSEY[SEQID262] PEPTIDE:YYGGEGSSSEQGYYGEGSSEEGY[SEQID263] PEPTIDE:YGEQQQQPGMTRVR[SEQID264] PEPTIDE:GEGSSEEGYYGEQQQQPGMTR[SEQID265] PEPTIDE:YGEGSSEEGYYGEQQQQPGMTR[SEQID266] PEPTIDE:QQQQPGMTRVR[SEQID267] PEPTIDE:QYAAQLPSMCRVEPQQCSIFAAGQY[SEQID268] PROTEIN:P0C1U8-5-Staphylococcusaureus MKGKFLKVSSLFVATLTTATLVSSPAANALSSKAMDNHPQQTQSSKQQTPKIQKGGNLKPLEQREHANVILPNNDRHQITDTTNGHYAPVTYI QVEAPTGTFIASGVVVGKDTLLTNKHVVDATHGDPHALKAFPSAINQDNYPNGGFTAEQITKYSGEGDLAIVKFSPNEQNKHIGEVVKPATMS NNAETQVNQNITVTGYPGDKPVATMWESKGKITYLKGEAMQYDLSTTGGNSGSPVFNEKNEVIGIHWGGVPNEFNGAVFINENVRNFLKQ NIEDIHFANDDQPNNPDNPDNPNNPDNPNNPDEPNNPDNPNNPDNPDNGDNNNSDNPDAA[SEQID14] PEPTIDE:APTGTFIASGVVVGKD[SEQID413] PEPTIDE:LAIVKFSPNEQNKHIGE[SEQID414] PEPTIDE:RHQITDTTNGHYAPVTYIQVE[SEQID415] PEPTIDE:GDLAIVKFSPNEQNKHIGE[SEQID416] PEPTIDE:NPDNPDNPNNPDNPNNPD[SEQID417] PROTEIN:P14614-4-RICE MATIAFSRLSIYFCVLLLCHGSMAQLFGPNVNPWHNPRQGGFRECRFDRLQAFEPLRRVRSEAGVTEYFDEKNEQFQCTGTFVIRRVIEPQGL LVPRYSNTPGMVYIIQGRGSMGLTFPGCPATYQQQFQQFLPEGQSQSQKFRDEHQKIHQFRQGDIVALPAGVAHWFYNEGDAPVVALYVF DLNNNANQLEPRQKEFLLAGNNNREQQMYGRSIEQHSGQNIFSGFNNELLSEALGVNALVAKRLQGQNDQRGEIIRVKNGLKLLRPAFAQQ QEQAQQQEQAQAQYQVQYSEEQQPSTRCNGLDENFCTIKARLNIENPSHADTYNPRAGRITRLNSQKFPILNLVQLSATRVNLYQNAILSPF WNVNAHSLVYIVQGHARVQVVSNLGKTVFNGVLRPGQLLIIPQHYVVLKKAEHEGCQYISFKTNANSMVSHLAGKNSIFRAMPVDVIANAYR ISREQARSLKNNRGEELGAFTPRYQQQTYPGFSNESENEALE[SEQID6] PEPTIDE:TVFNGVLRPGQL[SEQID269] PEPTIDE:TVFNGVLRPGQLL[SEQID270] PEPTIDE:SGFNNELLSEALGVNALVAK[SEQID271] PEPTIDE:NGVLRPGQL[SEQID272] PEPTIDE:ALVAKRLQGQNDQRGEl[SEQID273] PEPTIDE:VPRYSNTPGM[SEQID274] PEPTIDE:PRYSNTPGMV[SEQID275] PEPTIDE:YSNTPGMVY[SEQID276] PEPTIDE:LVPRYSNTPGM[SEQID277] PEPTIDE:FYNEGDAPVV[SEQID278] PEPTIDE:FYNEGDAPVVAL[SEQID279] PEPTIDE:FEPLRRVRSEAGVTE[SEQID280] PEPTIDE:FYNEGDAPVVALY[SEQID281] PEPTIDE:FYNEGDAPVVA[SEQID282] PROTEIN:P09918-14-Pisumsativum MFSGVTGILNRGHKIKGTVVLMRKNVLDINSLTTVGGVIGQGFDILGSTVDNLTAFLGRSVSLQLISATKPDATGKGKLGKATFLEGIISSLPTLG AGQSAFKIHFEWDDDMGIPGAFYIKNFMQTEFFLVSLTLDDIPNHGSIYFVCNSWIYNAKHHKIDRIFFANQTYLPSETPAPLVHYREEELNNLR GDGTGERKEWERIYDYDVYNDLGNPDSGENHARPVLGGSETYPYPRRGRTGRKPTRKDPNSESRSDYVYLPRDEAFGHLKSSDFLTYGLKAVS QNVVPALESVFFDLNFTPNEFDSFDEVHGLYEGGIKLPTNILSQISPLPVLKEIFRTDGENTLKYPPPKVIQVSRSGWMTDEEFAREMLAGVNPN VICCLQEFPPRSKLDSQIYGDHTSKISKEHLEPNLEGLTVEEAIQNKKLFLLDHHDSIMPYLRRINSTSTKAYATRTILFLNNNQNLKPLAIELSLPHP QGDEHGAVSYVYQPALEGVESSIWLLAKAYVIVNDSCYHQLVSHWLNTHAVVEPFVIATNRHLSCLHPIYKLLYPHYRDTMNINSLARLSLVND GGIIEKTFLWGRYSMEMSSKVYKNWVFTEQALPADLIKRGMAIEDPSSPCGVKLVVEDYPYAVDGLEIWAIIKTWVQDYVSLYYTSDEKLRQD SELQAWWKELVEVGHGDKKNEPWWPKMQTREDLIEVCSIVIWTASALHAAVNFGQYSYGGLILNRPTLSRRFMPEKGSAEFEELVKSPQKA YLKTITPKFQTLIDLSVIEILSRHASDELYLGERDNPNWTSDKRALEAFKKFGNKLAEIEKKLTQRNNDEKLRNRHGPVEMPYTLLYPSSKEGLTFR GIPNSISI[SEQID7] PEPTIDE:HGPVEMPYTLLYPSSK[SEQID283] PROTEIN:P02857-1-PEA MAKLLALSLSFCFLLLGGCFALREQPQQNECQLERLDALEPDNRIESEGGLIETWNPNNKQFRCAGVALSRATLQRNALRRPYYSNAPQEIFIQ QGNGYFGMVFPGCPETFEEPQESEQGEGRRYRDRHQKVNRFREGDIIAVPTGIVFWMYNDQDTPVIAVSLTDIRSSNNQLDQMPRRFYLAG NHEQEFLQYQHQQGGKQEQENEGNNIFSGFKRDYLEDAFNVNRHIVDRLQGRNEDEEKGAIVKVKGGLSIISPPEKQARHQRGSRQEEDED EEKQPRHQRGSRQEEEEDEDEERQPRHQRRRGEEEEEDKKERGGSQKGKSRRQGDNGLEETVCTAKLRLNIGPSSSPDIYNPEAGRIKTVTSL DLPVLRWLKLSAEHGSLHKNAMFVPHYNLNANSIIYALKGRARLQVVNCNGNTVFDGELEAGRALTVPQNYAVAAKSLSDRFSYVAFKTNDR AGIARLAGTSSVINNLPLDVVAATFNLQRNEARQLKSNNPFKFLVPARESENRASA[SEQID8] PEPTIDE:LDALEPDNR[SEQID284] PEPTIDE:DALEPDNR[SEQID285] PEPTIDE:HGSLHKNAMFVPHYNLNANSIIYA[SEQID286] PEPTIDE:LAGTSSVINNLPLDVVAATF[SEQID287] PEPTIDE:FREGDIIAVPTGIVFW[SEQID288] PEPTIDE:GTSSVINNLPLDVVAATFNLQRNE[SEQID289] PEPTIDE:KGAIVKVKGGLSIISPPE[SEQID290] PEPTIDE:RLAGTSSVINNLPLD[SEQID291] PEPTIDE:AGTSSVINNLPLDVVAATFNLQRNE[SEQID292] PEPTIDE:AGTSSVINNLPL[SEQID293] PEPTIDE:LAGTSSVINNLPLDVVA[SEQID294] PEPTIDE:AGTSSVINNLPLDV[SEQID295] PEPTIDE:AGRIKTVTSLDLPVLRW[SEQID296] PEPTIDE:AGRIKTVTSLDLPVLR[SEQID297] PEPTIDE:FREGDIIAVPTGIVF[SEQID298] PEPTIDE:AGTSSVINNLPLD[SEQID299] PEPTIDE:LAGTSSVINNLPL[SEQID300] PEPTIDE:LAGTSSVINNLPLDVV[SEQID301] PEPTIDE:EGDIIAVPTGIVF[SEQID302] PEPTIDE:LAGTSSVINNLPLDV[SEQID303] PEPTIDE:AGRALTVPQNYAVAAKSLSD[SEQID304] PEPTIDE:AGRALTVPQNYA[SEQID305] PEPTIDE:LAGTSSVINNLPLD[SEQID306] PEPTIDE:RAGIARLAGTSSVINNLPLDVVA[SEQID307] PROTEIN:P02855-4-PEA DNAEIEKILLEEHEKETHHRRGLRDKRQQSQEKNVIVKVSKKQIEELSKNAKSSSKKSVSSRSEPFNLKSSDPIYSNQYGKFFEITPKKNPQLQDLD IFVNYVEIKEGSLWLPHYNSRAIVIVTVNEGKGDFELVGQRNENQQGLREEDDEEEEQREEETKNQVQSYKAKLTPGDVFVIPAGHPVAVRAS SNLNLLGFGINAENNQRNFLAGEEDNVISQIQKQVKDLTFPGSAQEVDRLLENQKQSYFANAQPQQRETRSQEIKEHLYSILGAF[SEQID9] PEPTIDE:RASSNLNLLGFGINAE[SEQID308] PEPTIDE:VTVNEGKGDFEL[SEQID309] PEPTIDE:VRASSNLNLLGFGINAE[SEQID310] PEPTIDE:VRASSNLNLLGFG[SEQID311] PEPTIDE:HPVAVRASSNLNLLGFG[SEQID312] PEPTIDE:TKNQVQSYKAKLTPGD[SEQID313] PEPTIDE:HPVAVRASSNLNLLG[SEQID314] PEPTIDE:KAKLTPGDVFVIPAG[SEQID315] PEPTIDE:DLTFPGSAQEVDRLLENQK[SEQID316] PEPTIDE:PAGHPVAVR[SEQID317] PEPTIDE:AKLTPGDVFVIPAGHPVA[SEQID318] PEPTIDE:SYKAKLTPGDVFVIPAGHPVA[SEQID319] PEPTIDE:LTPGDVFVIPAGHPVAVR[SEQID320] PEPTIDE:VQSYKAKLTPGDVFVIPAG[SEQID321] PEPTIDE:YKAKLTPGDVFVIPAGHPVA[SEQID322] PEPTIDE:FVIPAGHPVAVR[SEQID323] PEPTIDE:YKAKLTPGDVFVIPAG[SEQID324] PEPTIDE:DLTFPGSAQEVDR[SEQID325] PEPTIDE:AKLTPGDVFVIPAGHPVAVR[SEQID326] PEPTIDE:LTPGDVFVIPAG[SEQID327] PEPTIDE:SYKAKLTPGDVFVIPAG[SEQID328] PEPTIDE:SYKAKLTPGDVFVIPAGHPVAVR[SEQID329] PEPTIDE:VIPAGHPVAVR[SEQID330] PEPTIDE:QVQSYKAKLTPGDVFVIPAG[SEQID331] PEPTIDE:AKLTPGDVFVIPAG[SEQID332] PEPTIDE:HPVAVRASSNLNLLGFGINAE[SEQID333] PEPTIDE:YKAKLTPGDVFVIPAGHPVAVR[SEQID334] PEPTIDE:TKNQVQSYKAKLTPGDVFVIPAG[SEQID335] PEPTIDE:PFNLKSSDPIYS[SEQID336] PEPTIDE:IEKILLEE[SEQID337] PEPTIDE:SRSEPFNLKSSDPIYS[SEQID338] PEPTIDE:HPVAVRASSNLNL[SEQID339] PROTEIN:D3VNE1-5-PEA MAATPIKPLMLLAIAFLASVCVSSRSDQENPFIFKSNRFQTLYENENGHIRLLQKFDKRSKIFENLQNYRLLEYKSKPRTLFLPQYTDADFILVVLSG KATLTVLKSNDRNSFNLERGDTIKLPAGTIAYLANRDDNEDLRVLDLTIPVNKPGQLQSFLLSGTQNQPSLLSGFSKNILEAAFNTNYEEIEKVLLE QQEQEPQHRRSLKDRRQEINEENVIVKVSREQIEELSKNAKSSSKKSVSSESGPFNLRSRNPIYSNKFGKFFEITPEKNQQLQDLDIFVNSVDIKE GSLLLPNYNSRAIVIVTVTEGKGDFELVGQRNENQGKENDKEEEQEEETSKQVQLYRAKLSPGDVFVIPAGHPVAINASSDLNLIGFGINAENN ERNFLAGEEDNVISQVERPVKELAFPGSSHEVDRLLKNQKQSYFANAQPLQRE[SEQID10] PEPTIDE:TLFLPQYTDADFILVVLSGK[SEQID340] PROTEIN:P07728-1-RICE MASINRPIVFFTVCLFLLCNGSLAQQLLGQSTSQWQSSRRGSPRECRFDRLQAFEPIRSVRSQAGTTEFFDVSNEQFQCTGVSVVRRVIEPRGL LLPHYTNGASLVYIIQGRGITGPTFPGCPESYQQQFQQSGQAQLTESQSQSQKFKDEHQKIHRFRQGDVIALPAGVAHWCYNDGEVPVVAIY VTDLNNGANQLDPRQRDFLLAGNKRNPQAYRREVEERSQNIFSGFSTELLSEALGVSSQVARQLQCQNDQRGEIVRVEHGLSLLQPYASLQE QEQGQVQSRERYQEGQYQQSQYGSGCSNGLDETFCTLRVRQNIDNPNRADTYNPRAGRVTNLNTQNFPILSLVQMSAVKVNLYQNALLSPF WNINAHSVVYITQGRARVQVVNNNGKTVFNGELRRGQLLIIPQHYAVVKKAQREGCAYIAFKTNPNSMVSHIAGKSSIFRALPNDVLANAYRI SREEAQRLKHNRGDEFGAFTPIQYKSYQDVYNAAESS[SEQID11] PEPTIDE:EVEERSQNIF[SEQID341] PEPTIDE:VEERSQNIFSGF[SEQID342] PEPTIDE:ASLQEQEQGQVQ[SEQID343] PEPTIDE:QEQEQGQVQSR[SEQID344] PEPTIDE:ASLQEQEQGQVQSR[SEQID345] PEPTIDE:EVEERSQNIFSGF[SEQID346] PEPTIDE:VTDLNNGANQLDPRQRD[SEQID347] PEPTIDE:VEHGLSLLQPYASL[SEQID348] PEPTIDE:IYVTDLNNGANQLDPRQRDFL[SEQID349] PEPTIDE:VTDLNNGANQLDPRQRDFL[SEQID350] PEPTIDE:VEHGLSLLQPYASLQEQEQGQVQSR[SEQID351] PEPTIDE:VTDLNNGANQLDPR[SEQID352] PEPTIDE:IYVTDLNNGANQLDPRQRD[SEQID353] PEPTIDE:YVTDLNNGANQLDPRQRDFL[SEQID354] PEPTIDE:YVTDLNNGANQLDPR[SEQID355] PEPTIDE:STELLSEALGVSSQVAR[SEQID356] PEPTIDE:HGLSLLQPYASLQEQE[SEQID357] PEPTIDE:SGFSTELLSEALGVSSQVAR[SEQID358] PROTEIN:P07730-2-RICE MASINRPIVFFTVCLFLLCDGSLAQQLLGQSTSQWQSSRRGSPRGCRFDRLQAFEPIRSVRSQAGTTEFFDVSNELFQCTGVSVVRRVIEPRGLL LPHYTNGASLVYIIQGRGITGPTFPGCPETYQQQFQQSGQAQLTESQSQSHKFKDEHQKIHRFRQGDVIALPAGVAHWCYNDGEVPVVAIYV TDINNGANQLDPRQRDFLLAGNKRNPQAYRREVEEWSQNIFSGFSTELLSEAFGISNQVARQLQCQNDQRGEIVRVERGLSLLQPYASLQEQ EQGQMQSREHYQEGGYQQSQYGSGCPNGLDETFCTMRVRQNIDNPNRADTYNPRAGRVTNLNSQNFPILNLVQMSAVKVNLYQNALLSP FWNINAHSIVYITQGRAQVQVVNNNGKTVFNGELRRGQLLIVPQHYVVVKKAQREGCAYIAFKTNPNSMVSHIAGKSSIFRALPTDVLANAYR ISREEAQRLKHNRGDEFGAFTPLQYKSYQDVYNVAESS[SEQID12] PEPTIDE:GAFTPLQYKSYQD[SEQID359] PEPTIDE:GLLLPHYTNGASLVY[SEQID360] PEPTIDE:FLLAGNKRNPQAYRRE[SEQID361] PEPTIDE:ALPTDVLANAYR[SEQID362] PEPTIDE:DFLLAGNK[SEQID363] PEPTIDE:DVLANAYR[SEQID364] PEPTIDE:GAFTPLQYK[SEQID365] PEPTIDE:QGDVIALPAGVAHW[SEQID366] PEPTIDE:FGAFTPLQYKSY[SEQID367] PEPTIDE:FLLAGNKRNPQAYR[SEQID368] PEPTIDE:FGAFTPLQYKSYQ[SEQID369] PEPTIDE:GLSLLQPYASLQEQE[SEQID370] PEPTIDE:AFTPLQYK[SEQID371] PEPTIDE:FGAFTPLQYKSYQD[SEQID372] PEPTIDE:GDEFGAFTPLQYK[SEQID373] PEPTIDE:FGAFTPLQYKSYQDV[SEQID374] PEPTIDE:FGAFTPLQYK[SEQID375] PEPTIDE:FGAFTPLQYKS[SEQID376] PEPTIDE:VYIIQGRGITGPTF[SEQID377] PEPTIDE:YIIQGRGITGPTF[SEQID378] PEPTIDE:KTNPNSMVSHIAGK[SEQID379] PEPTIDE:TNPNSMVSHIAGK[SEQID380] PEPTIDE:PNSMVSHIAGKS[SEQID381] PEPTIDE:NIDNPNRADTYNPRAGRVTN[SEQID382] PEPTIDE:QRDFLLAGNKR[SEQID383] PEPTIDE:LLQPYASLQEQE[SEQID384] PEPTIDE:QRDFLLAGNK[SEQID385] PEPTIDE:QEQEQGQMQSR[SEQID386] PEPTIDE:SLLQPYASLQEQE[SEQID387] PEPTIDE:ASLQEQEQGQM[SEQID388] PEPTIDE:ASLQEQEQGQMQSR[SEQID389] PEPTIDE:DFLLAGNKR[SEQID390] PEPTIDE:QAFEPIRSVRSQAGTTEF[SEQID391] PEPTIDE:KTNPNSMVSHIAGKSSIF[SEQID392] PEPTIDE:VRRVIEPRGLLLPHYTNGASL[SEQID393] PEPTIDE:FGAFTPLQYKSYQDVYN[SEQID394] PEPTIDE:IALPAGVAHW[SEQID395] PEPTIDE:RVRQNIDNPNRADTYNPRAGRVTNL[SEQID396] PEPTIDE:NIDNPNRADTYNPRAGRVTNL[SEQID397] PEPTIDE:GAFTPLQYKSYQDVYN[SEQID398] PEPTIDE:PNSMVSHIAGKSSIFR[SEQID399] PEPTIDE:RLQAFEPIRSVRSQAGTTE[SEQID400] PEPTIDE:TNPNSMVSHIAGKSSIFR[SEQID401] PROTEIN:Q0D7S0-3-RICE MASNKVVFSVLLLAVVSVLAATATMAEYHHQDQVVYTPGPLCQPGMGYPMYPLPRCRALVKRQCVGRGTAAAAEQVRRDCCRQLAAVDD SWCRCEAISHMLGGIYRELGAPDVGHPMSEVFRGCRRGDLERAAASLPAFCNVDIPNGGGGVCYWLARSGY[SEQID13] PEPTIDE:ELGAPDVGHPM[SEQID402] PEPTIDE:LGAPDVGHPM[SEQID403] PEPTIDE:ELGAPDVGHPMSEVF[SEQID404] PEPTIDE:ELGAPDVGHPMS[SEQID405] PEPTIDE:ELGAPDVGHPMSEVFR[SEQID406] PEPTIDE:ELGAPDVGHPMSEV[SEQID407] PEPTIDE:ELGAPDVGHPMSE[SEQID408] PEPTIDE:LGAPDVGHPMSE[SEQID409] PEPTIDE:YRELGAPDVGHPMSE[SEQID410] PEPTIDE:LGAPDVGHPMSEV[SEQID411] PEPTIDE:RELGAPDVGHPMSE[SEQID412] ADDITIONALPEPTIDES(ANDSOURCEPROTEIN) HPRPPKPDAPR[SEQID452]-Q0D9DO LQQAPPPPQR[SEQID453]-Q6AVS5 VGWGEQPWSPY[SEQID454]-Q8H920 FHMPP[SEQID455]-O49927 FRRP[SEQID456]-P29835 FWM[SEQID457]-P15838 HMPPS[SEQID458]-049927 PVEMPTLLYPS[SEQID459 HMPSS[SEQID460]-O49927 HRFR[SEQID461]-Q712V4 HRRS[SEQID462]-P13918 HSPR[SEQID463]-P14323 HWF[SEQID464-P14323 MFRR[SEQID465]-Q41000 MFRRP[SEQID466-P29835 MPPS[SEQID467]-049927 MPRR[SEQID468]-P15838 NMPS[SEQID469]-P20698 PHMP[SEQID470]-O49927 PHMPS[SEQID471-O49927 PRRF[SEQID472]-P15838 WMK[SEQID473]-O04434 DSINALEPDHR[SEQID474]-P05692 ELTFPGSVQ[SEQID475]-Q9M3X6 ELTFPGSVQE[SEQID476]-Q9M3X6 IFEDAITIPGR[SEQID477]-P09886 LDALEPDNRIESE[SEQID478]-P02857 KTLDYWPSLR[SEQID479]-P08688 RHGEWGPSY[SEQID480 ILVDGSHDIER[SEQID481]-Q5N725 LVSHPIAAHEGR[SEQID482]-P14614 NLAQAPAQALL[SEQID483]-Q0DJ38 FLPQHTD[SEQID484]-P13918 LEPDNR[SEQID485]-P15838 LQSQND[SEQID486]-P14323 LQSQNDQRGEI[SEQID487]-P14323 QSQNDQRGEIIHVK[SEQID488]-P14323 RGEIIHVK[SEQID489]-P14323 RLQSQNDQ[SEQID490]-P14323 RLQSQNDQRG[SEQID491]-P14323 RLQSQNDQRGEIIH[SEQID492]-P14323 VFDGVLRPG[SEQID493]-P14323 HNPR[SEQID494]-P14614 HPMS[SEQID495]-Q0D7S0 HPSF[SEQID496]-Q0DEV5 MPMP[SEQID497]-P29835 PMPL[SEQID498]-P29835 PNSM[SEQID499]-P07728 WDP[SEQID500]-B5A8N6 LRGFSK[SEQID501]-Q9M3X6 RSQNIF[SEQID502]-P07728 YLRGFS[SEQID503]-Q9M3X6 GALMLPHYN[SEQID504]-Q9M3X6 GALMLPHYNSR[SEQID505]-Q9M3X6 KNPQLQDLDIFVNYVEIK[SEQID700]P02855 PGQLQSFLLSGNQNQQNYLSGFSK[SEQID701]P13918 RGPQQYAEWQINEK[SEQID702]Q6K7K6 VLDLAIPVNRPGQL[SEQID703]Q6K508 GYVGLTFPGCPATHQQQFQLFEQR[SEQID704]P09918 LDVTPLSLGL[SEQID717] EEGIQLVAEAIR[SEQID718] YSLKPLVPR[SEQID719] WHT[SEQID720] WHN[SEQID721] NNPF[SEQID722] MRFR[SEQID723] MPPSS[SEQID724] HMPS[SEQID725] HMPPS[SEQID726] GHPM[SEQID727] FWN[SEQID728] FHMP[SEQID729] WTIVQGLPIDE[SEQID730] GYPMYPLPR[SEQID731] HGGEGGRPY[SEQID732] LRGFSK[SEQID733] GALMLPHYN[SEQID734] GALMLPHYNSR[SEQID735] VFDGVLRPG[SEQID736] LQSQND[SEQID737] LQSQNDQRGEI[SEQID738] QSQNDQRGEIIHVK[SEQID739] RGEIIHVK[SEQID740] RLQSQNDQ[SEQID741] RLQSQNDQRG[SEQID742] RLQSQNDQRGEIIH[SEQID743] MPMP[SEQID744] PMPL[SEQID745] LEPDNR[SEQID746] GIARLAGTSSVIN[SEQID747] RSQNIF[SEQID748] PNSM[SEQID749] GHPM[SEQID750] HPMS[SEQID751] FLPQHTD[SEQID752] EWQINEK[SEQID753] GPQQYAEWQINEK[SEQID754] PQQYAEWQ[SEQID755] RGPQQYA[SEQID756] HNPR[SEQID757] WHN[SEQID758] WDP[SEQID759] HPSF[SEQID760] PGQLQSFLLSGNQNQQNYLSGF[SEQID761] QLQSFLLSGNQNQQNYLSGFSK[SEQID762] QSFLLSGNQNQQ[SEQID763] PGQLQSFLLSGN[SEQID764] QSFLLSGNQ[SEQID765] QNQQNYLSGFSK[SEQID766] YLRGFS[SEQID767] PVEMPTLLYPS[SEQID768] RGPQQYAEWQINE[SEQID769] GYVGLTFPGCPATHQQQFQLFEQR[SEQID770] KNPQLQDLDIFVNYVEIK[SEQID771] PGQLQSFLLSGNQNQQNYLSGFSK[SEQID772] RGPQQYAEWQINEK[SEQID773] VLDLAIPVNRPGQL[SEQID774] RGPQQYAEWQINEK[SEQID775] PROTEINP02855[SEQID546-552] PEPTIDE:SRAIVIVTVNE PEPTIDE:AKLTPGDV PEPTIDE:IVIVTVNEGK PEPTIDE:LDALEPDNRIESEGGL(alsoinP02857) PEPTIDE:RPYYSNAPQE(alsoinP02857) PEPTIDE:LDALEPDNRIESEGGLIETWNPNNK(alsoinP02857) PEPTIDE:AIVIVTVNEGK(alsoinP13918) PROTEINP02857[SEQID553-565 PEPTIDE:LQVVNCNGNTVFDGEL PEPTIDE:QVVNCNGNTVFDGEL PEPTIDE:IIAVPTGIVF PEPTIDE:GRRYRDRHQKVNRFRE PEPTIDE:RPYYSNAPQEI PEPTIDE:RLDALEPDNRIE PEPTIDE:RLDALEPDNRIESE PEPTIDE:LDALEPDNRIESEGGLIETW PEPTIDE:LDALEPDNRIE PEPTIDE:LDALEPDNRIESEGGLIE PEPTIDE:LDALEPDNRIESEGGL(alsoinP02855) PEPTIDE:RPYYSNAPQE(alsoinP02857) PEPTIDE:LDALEPDNRIESEGGLIETWNPNNK(alsoinP02855) PROTEINP07728[SEQID566-609] PEPTIDE:VEHGLSLLQPYASLQEQEQGQVQSRER PEPTIDE:RSQNIFSGF PEPTIDE:GITGPTFPGCPESY PEPTIDE:CNGS PEPTIDE:SPREC PEPTIDE:PREC PEPTIDE:PRECR PEPTIDE:CPES PEPTIDE:SGCS PEPTIDE:CSNG PEPTIDE:RSQNIFSGFSTE PEPTIDE:VEEWSQNIFSGFST PEPTIDE:WSQNIFSGFSTEL PEPTIDE:WSQNIFSGFSTE PEPTIDE:STSQWQSSRR PEPTIDE:NRPI PEPTIDE:CDGS PEPTIDE:PRGC PEPTIDE:PRGCR PEPTIDE:RGCR PEPTIDE:GCRF PEPTIDE:PTFP PEPTIDE:PGCPE PEPTIDE:GCPE PEPTIDE:CPET PEPTIDE:AHWC PEPTIDE:HWCY PEPTIDE:SGCP PEPTIDE:SGCPN PEPTIDE:GCPN PEPTIDE:CPNG PEPTIDE:TFCTM PEPTIDE:FCTM PEPTIDE:FCTMR PEPTIDE:CTMR PEPTIDE:EGCA PEPTIDE:SQNIFSGFSTELL PEPTIDE:SQNIFSGFSTE PEPTIDE:QNDQRGEIVR PEPTIDE:SQNIFSGFSTEL(alsoinP07730) PEPTIDE:QLQCQNDQRGEI(alsoinP07730) PEPTIDE:LGQSTSQWQSSR(alsoinP07730) PEPTIDE:QQLLGQSTSQWQSSR(alsoinP07730) PEPTIDE:LLGQSTSQWQSSR(alsoinP07730) PROTEINP07730[SEQID610-619] PEPTIDE:NDQRGEIVR PEPTIDE:GQSTSQWQSSR PEPTIDE:STSQWQSSR PEPTIDE:GITGPTFPGCPET PEPTIDE:GITGPTFPGCPETY PEPTIDE:SQNIFSGFSTEL(alsoinP07728) PEPTIDE:QLQCQNDQRGEI(alsoinP07728) PEPTIDE:LGQSTSQWQSSR(alsoinP07728) PEPTIDE:QQLLGQSTSQWQSSR(alsoinP07728) PEPTIDE:LLGQSTSQWQSSR(alsoinP07728) PROTEINP09918[620-630] PEPTIDE:IFFANQTYL PEPTIDE:EHLEPNLEGLTVEE PEPTIDE:IFFANQTYLPSETPAPLVHYREEELNNLRGDGTGER PEPTIDE:IHFEWDDDMGIPGAFYIK PEPTIDE:IFFANQTYLPSETPAPLVHYREEELNNLR PEPTIDE:TEQALPADLIK PEPTIDE:EHLEPNLEGLTVEEAIQNKK PEPTIDE:ISKEHLEPNLEGLTVEEAIQNKK PEPTIDE:LSLPHPQGDEHGAVSY PEPTIDE:ISKEHLEPNLEGLTVEEAIQNK PEPTIDE:EHLEPNLEGLTVEEAIQNK PROTEINP0C1U8[SEQID631] PEPTIDE:LSTTGGNSGSPVFNEKNE PROTEINP13918[SEQID632-639] PEPTIDE:QSFLLSGNQNQQNYLSG PEPTIDE:VLDLAIPVNRPGQLQS PEPTIDE:VLDLAIPVNRPGQLQSFL PEPTIDE:FLLSGNQNQQNYLSG PEPTIDE:FLLSGNQNQQNYLSGFSK PEPTIDE:DPQNPFIFKSNKFQTLFE PEPTIDE:ELAFPGSAQEVDRILENQK PEPTIDE:AIVIVTVNEGK(alsoinP02855) PROTEINP14323[SEQID640-667] PEPTIDE:INAVAAKRLQSQNDQRGE PEPTIDE:NRAQQQQVYGSSIE PEPTIDE:PSTNPWHSPR PEPTIDE:CHGS PEPTIDE:CHGSM PEPTIDE:PWHS PEPTIDE:FREC PEPTIDE:RECR PEPTIDE:ECRF PEPTIDE:CRFD PEPTIDE:CRFDR PEPTIDE:CTGT PEPTIDE:FPGC PEPTIDE:FPGCP PEPTIDE:PGCP PEPTIDE:PGCPA PEPTIDE:PGCPAT PEPTIDE:GCPA PEPTIDE:CPAT PEPTIDE:ENFC PEPTIDE:NFCT PEPTIDE:NFCTI PEPTIDE:FCTI PEPTIDE:AQQQQVYGSSIEQH PEPTIDE:AQQQQVYGSSIEQHSGQNIFSGF PEPTIDE:AAKRLQSQNDQRGE PEPTIDE:QARSLKNNRGEE(alsoinP14614) PEPTIDE:FNPSTNPWHSPRQGS(alsoinQ0DEV5) PROTEINP14614[SEQID668] PEPTIDE:QARSLKNNRGEE(alsoinP14323) PROTEINQ0D7S0[SEQID669] PEPTIDE:AAASLPAFCNVDIPNGGGGVCYWLAR PROTEINQ0DEV5[SEQID670-680] PEPTIDE:VAGSAPGIEGDEIAPLAK PEPTIDE:LGVAGSAPGIEGDEIAPLAKEN PEPTIDE:GSAPGIEGDEIAPLAKE PEPTIDE:VAGSAPGIEGDEIAP PEPTIDE:GVAGSAPGIEGDEIAPLAK PEPTIDE:GVAGSAPGIEGDEIAPLAKEN PEPTIDE:VAGSAPGIEGDEIAPLAKEN PEPTIDE:SAPGIEGDEIAPLAK PEPTIDE:GSAPGIEGDEIAPLAK PEPTIDE:SAPGIEGDEIAPLAKEN PEPTIDE:FNPSTNPWHSPRQGS(alsoinP14323) PROTEINQ9M3X6[SEQID681-699] PEPTIDE:VDLVIPVNGPGK PEPTIDE:LVDLVIPVNGPGK PEPTIDE:IKLPAGTTSY PEPTIDE:IKLPAGTTSYL PEPTIDE:RRNPFLFKSNKF PEPTIDE:IENPVKELTFPGSVQEINR PEPTIDE:RRNPFLFKSNKFLT PEPTIDE:AKPHTIFLPQHIDA PEPTIDE:AKPHTIFLPQHIDAD PEPTIDE:KQKYRYQRE PEPTIDE:KQKYQYQRE PEPTIDE:MLPH PEPTIDE:RRNPFLFKSNKFLTLFENE PEPTIDE:PFLFKSNKFLTLFE PEPTIDE:SQERRNPFLFKSNKFLTLFE PEPTIDE:RRNPFLFKSNKFLTLFE PEPTIDE:SQERRNPFLFKSNKFLTLFENE PEPTIDE:LTFPGSVQE PEPTIDE:ELTFPGSVQEINR RiceProtein:Q0D9D0 MLCLTSSSSSAPAPLLPSLADRPSPGIAGGGGNVRLSVVSSPRRSWPGKVKTNFSVPATA RKNKTMVTVVEEVDHLPIYDLDPKLEEFKDHFNYRIKRYLDQKCLIEKHEGGLEEFSKGY LKFGINTVDGATIYREWAPAAQEAQLIGEFNNWNGAKHKMEKDKFGIWSIKISHVNGKPA IPHNSKVKFRFRHGGGAWVDRIPAWIRYATFDASKFGAPYDGVHWDPPACERYVFKHPRP PKPDAPRIYEAHVGMSGEEPEVSTYREFADNVLPRIRANNYNTVQLMAIMEHSYYASFGY HVTNFFAVSSRSGTPEDLKYLVDKAHSLGLRVLMDVVHSHASNNVTDGLNGYDVGQNTHE SYFHTGDRGYHKLWDSRLFNYANWEVLRFLLSNLRYWMDEFMFDGFRFDGVTSMLYHHHG INKGFTGNYKEYFSLDTDVDAIVYMMLANHLMHKLLPEATIVAEDVSGMPVLCRPVDEGG VGFDFRLAMAIPDRWIDYLKNKEDRKWSMSEIVQTLTNRRYTEKCIAYAESHDQSIVGDK TIAFLLMDKEMYTGMSDLQPASPTINRGIALQKMIHFITMALGGDGYLNFMGNEFGHPEW IDFPREGNNWSYDKCRRQWSLVDTDHLRYKYMNAFDQAMNALEEEFSFLSSSKQIVSDMN EKDKVIVFERGDLVFVFNFHPNKTYKGYKVGCDLPGKYRVALDSDALVFGGHGRVGHDVD HFTSPEGMPGVPETNFNNRPNSFKVLSPPRTCVAYYRVDEDREELRRGGAVASGKIVTEY IDVEATSGETISGGWKGSEKDDCGKKGMKFVFRSSDEDCK[SEQID705] Riceprotein:Q6AVS5 MDRYQRVERPRPESAIEENEIRITAQGLIRNYVSYATSLLQDRRIKEIVLKAMGQAISKS VAVAEIIKKRVPGLYQDTNISSVSITDVWEPIEEGLVPLEMTRHVSMISITLSPRDLDKN SPGYQTPVYVEQPRQQPRLQQAPPPPQRQVRQPPPDYEDSYVRGRGRGRGRGRGRGWGRG GYGGYGGYGNNQGGYNQGGGYYDNQGGYGGYDNQGGYGGYDNQGGYGGGGYGYNQGRYGN YQENGGYNRGRGGMRGRGNWNYRGGYERGRGGGFPGGRGYGGRGRGRMGGRGGRGN [SEQID706] RiceProtein:Q8H920 MALEHLGRRNVAGSLLLLNLLMYVFLLGFAGWALNSSIKNAGADVGVGWGEQPWSPYYRQ SAWFASRFHLATFAALAGALGVAAKASAAYHGGRSGASWRPQGLAAAASLGTAAWAATAL AFGVACREIHDAAAAGPAGAARGWRMRALEGLTVTLAFTQLLYVLLLHAAVAGERCGLAC AADA[SEQID707] Peaprotein:O49927 MAIKTKLSLTIFLFFLLALLCSNLAVGRKEKDPELTTCKDQCDMQRQYDEEDKRICMERC DDYIKKKQERQKHKEHEEEEEQEQEEDENPYVFEDNDFETKIDTKDGRVLILNKFNEKSK LLKNIENYGLAVLEIKANAFLSPHHYDSEAILFNIKGRGIIGLVAEDRTERFNLEEGDIM RVPAGTPMYLVNRDENEKLYIAAFHMPPSSGSAPVNLEPFFESAGRKPESVLNTFSSKVL QAALKSSKGELETVLDEQKKGRIFKIEKEDVRGLAPKKSLWPFGGPFKSPFNIFSNNPAF SNKFGSLFEVGPSQEKSGLEGLNLMLTLANITKGSMSTIHYNTNANKIALVIDGEGELEM ACPHMPSSSSNSRQKKSSISYHNINAKLRPGVMFVVPAGHPFVNIASKKKNLIVVCFEVN AQRNKKLALAGKKNIVSALDKAAKEVAFDIAAEKVDEVFERKEEFFFPYDNEERKEEHGR AVV[SEQID708] Peaprotein:Q41000 MFRRATSTFLSRASATRRFSTDVATPATNSSFVEAWRKVSPNIDPPKTPLEFLKTRPPVP STIPTKLTVNFVLPYSSQLAAKEVDSVIIPATTGEMGVLPGHVATIAELKPGVLTVQEGT DTTKYFVSSGFRFIHANSVADIIAVEAVPVNQLDRDLVQKGLQEFTQKLNSATTDLEKRE AQIGIDVDSALNSALTG[SEQID709] RiceProtein:P20698 MKIIFFFALLAIAACSASAQFDAVTQVYRQYQLQPHLMLQQQMLSPCGEFVRQQCSTVAT PFFQSPVFQLRNCQVMQQQCCQQLRMIAQQSHCQAISSVQAIVQQLRLQQFASVYFDQSQ AQAQAMLALNMPSICGIYPSYNTAPCSIPTVGGIWY[SEQID710] PeaProtein:O04434 MQDSSTMKFSPLDLMTAIIKGKFNPSNDSSQAPASIIFENREFVMILTTSIAVLIGCVVV LIWRRSNSNKSKQIEVPKLVIKKLPELDVDDGKKKVTVFFGTQTGTAEGFAKAIAEEAKA RYEKAKFRVVDMDDYAADDDEYLEKLKRETMALFFLATYGDGEPTDNAARFYKWFTEEYE GEEDSFKNLSYGVFGLGNRQYEHFNKVAKVVDDKLLEQGGKRLVPVGLGDDDQCIEDDFT AWKEELWPALDQLLRDEDDTPVATPYTAAVSEYRVVIHDPLDATVDEKKRHNVNGHAVVD AQHPVRANVAVRRELHTPASDRSCTHLEFDISGTGVVYETGDHVGVYCENLSDTVEEAER ILGLSPDTYLSIHTDDEEGKPLGGSSLPPPFPPCTLRTALTKYADLLSSPKKSALVALAA HASDPSEADRLRHLASPAGKDEYAEWVISSQRSLLEVMAEFSSAKPPIGVFFAAVAPRLQ PRYYSISSSPRMAPSRIHVTCALVHDKMPTGRIHKGVCSTWMKNSVPLEKNQDCSWAPIF VRQSNFRLPADNKVPVIMIGPGTGLAPFRGFLQERLALKEDGAELGPSVLFFGCRNRQVD YIYEDELNHFVNGGALSELIVAFSRDGPTKEYVQHKMMEKASDIWNMISQGAYVYVCGDA KGMARDVHRTLHTILQEQGSLDSSKTESMVKNLQMTGRYLRDVW[SEQID711] RiceProtein:Q5N725 MSAYCGKYKDELIKNAAYIGTPGKGILAADESTGTIGKRFASINVENVEENRRSLRELLF TTPGALQHLSGVILFEETLYQKTKDGKPFVDVLKEGGVLPGIKVDKGTVEVAGTNKETTT QGHDDLGKRCAKYYEAGARFAKWRAVLKIGPNEPSQLSIDLNAQGLARYAIICQENGLVP IVEPEILVDGSHDIERCAYVTEKVLAACYKALNEHHVLLEGSLLKPNMVTPGSESKKVSP QLIAEYTVRALQRTVPAAVPAIVFLSGGQSEEEATVNLNAMNKLSTKKPWALSFSFGRAL QQSTLKAWGGKTENVVKAQKAFITRCKANSEATLGTYQGDAVLGEGASESLHVKDYKY [SEQID712] PeaProtein:B5A8N6 MASLQTQMISFYAIFLSILLTTILFFKVNSTETTSFLITKFSPDQQNLIFQGDGYTTKEK LTLTKAVKNTVGRALYSSPIHIWDRETGNVANFVTSFTFVINAPNSYNVADGFTFFIAPV DTKPQTGGGYLGVFNSAEYDKTTQTVAVEFDTFYNAAWDPSNRDRHIGIDVNSIKSVNTK SWKLQNGEEANVVIAFNAATNVLTVSLTYPNSLEEENVTSYTLSDVVSLKDVVPEWVRIG FSATTGAEYAAHEVLSWSFHSELSGTSSSKQAADA[SEQID713] RiceProtein:Q6K508 MATTTSLLSSCLCALLLAPLFSQGVDAWESRQGASRQCRFDRLQAFEPLRKVRSEAGDTE YFDERNEQFRCAGVFVIRRVIEPQGLVVPRYSNTPALAYIIQGKGYVGLTFPGCPATHQQ QFQLFEQRQSDQAHKFRDEHQKIHEFRQGDVVALPASVAHWFYNGGDTPAVVVYVYDIKS FANQLEPRQKEFLLAGNNQRGQQIFEHSIFQHSGQNIFSGFNTEVLSEALGINTEASKRL QSQNDQRGDIIRVKHGLQLLKPTLTQRQEEHRQYQQVQYREGQYNGLDENFCTIKARVNI ENPSRADYYNPRAGRITLLNNQKFPILNLIGMGAARVNLYQNALLSPFWNINAHSVVYII QGSVRVQVANNQGRSVFNGVLHQGQLLIIPQNHAVIKKAEHNGCQYVAIKTISDPTVSWV AGKNSILRALPVDVIANAYRISRDEARRLKNNRADEIGPFTPRFPQKSQRGYQFLTEGLS LIGM[SEQID714] PEAPROTEIN:Q712V4 QKAPRKQLATKAARKSAPATGGVKKPHRFRPGTVALREIRKYQKSTELLIRKLPFQRLVR EIAQDFKTDLRFQSSAVSALQEAAEAYLVGLFEDTNLCAIHAKRVTIMPKDIQLARRIRG ERA[SEQID715] PeaProtein:P09886 MAQSVSLSTIASPILSQKPGSSVKSTPPCMASFPLRRQLPRLGLRNVRAQAGGDGDNKDN SVEVHRVNKDDQGTAVERKPRRSSIDISPFGLLDPWSPMRSMRQMLDTMDRIFEDAITIP GRNIGGGEIRVPWEIKDEEHEIRMRFDMPGVSKEDVKVSVEDDVLVIKSDHREENGGEDC WSRKSYSCYDTRLKLPDNCEKEKVKAELKDGVLYITIPKTKIERTVIDVQ1Q[SEQID716] Examplesofhomologsforeachprotein P13918(Pea) >gi|137584|sp|P08438.1|VCL_VICFARecName:Full=Vicilin;Flags:Precursor[Viciafaba] >gi|22057|emb|CAA68559.1|vicilin[Viciafabavar.minor] >gi|383931031|gb|AFH56916.1|vicilin[Viciafaba] MAATTLKDSFPLLTLLGIAFLASVCLSSRSDQDNPFVFESNRFQTLFENENGHIRLLQKFDQHSKLLENLQNYRLLEYKSKPHTIFLPQQTDADFIL VVLSGKAILTVLLPNDRNSFSLERGDTIKLPAGTIGYLVNRDDEEDLRVLDLVIPVNRPGEPQSFLLSGNQNQPSILSGFSKNILEASFNTDYKEIEK VLLEEHGKEKYHRRGLKDRRQRGQEENVIVKISRKQIEELNKNAKSSSKKSTSSESEPFNLRSREPIYSNKFGKFFEITPKRNPQLQDLNIFVNYVEI NEGSLLLPHYNSRAIVIVTVNEGKGDFELVGQRNENQQGLREEYDEEKEQGEEEIRKQVQNYKAKLSPGDVLVIPAGYPVAIKASSNLNLVGFGI NAENNQRYFLAGEEDNVISQIHKPVKELAFPGSAQEVDTLLENQKQSHFANAQPRERERGSQEIKDHLYSILGSF[SEQID506] >gi|502105533|ref|XP_004492829.1|PREDICTED:vicilin-likeisoformX1[Cicerarietinum]ChickPea MAIKARFPLLVLLGIVFLASVCAKSDKENPFFFKSNNCQTLFENENGHVRLLQRFDKRSQLFENLQNYRLMEYNSKPHTLFLPQHNDADFILVVL RGRAILTVLNPNDRNTFKLERGDTIKLPAGTIAYLANRDDNEDLRVLDLAIPVNRPGQFQSFSLSGNENQQSYFQGFSKKILEASFNSDYEEIERV LLEEQEQKPEQRRGHKGRQQSQETDVIVKISREQIEELSKNAKSNCKKSVSSESEPFNLRSRSPIYSNRFGNFFEITPEKNPQLKDLDIFVNSVEIK EGSLLLPHFNSRATVILVVNEGKGEVELVGLRNENEQENKKEDEEEEEDRNVQVQRFQSKLSSGDVVVIPASHPFSINASSDLFLLGFGINAQN NQRNFLAGEEDNVISQIQRPVKEVAFPGSAEEVDRLLKNQRQSHFANAQPQQKRKGSQRIRSPF[SEQID507] >gi|29539109|emb|CAD87730.1|allergenLenc1.0101[Lensculinaris]Lentil SRSDQENPFIFKSNRFQTIYENENGH1RLLQRFDKRSKIFENLQNYRLLEYKSKPHTIFLPQFTDADFILVVLSGKAILTVLNSNDRNSFNLERGDTI KLPAGTIAYLANRDDNEDLRVLDLAIPVNRPGQLQSFLLSGTQNQPSFLSGFSKNILEAAFNTEYEElEKVLLEEQEQKSQHRRSLRDKRQEITNE DVIVKVSREQIEELSKNAKSSSKKSVSSESEPFNLRSRNPIYSNKFGKFFEITPEKNPQLQDLDIFVNSVEIKEGSLLLPNYNSRAIVIVTVNEGKGDF ELVGQRNENQQEQREENDEEEGQEEETTKQVQRYRARLSPGDVLVIPAGHPVAINASSDLNLIGFG1NAKNNQRNFLAGEEDNVISQIQRPV KELAFPGSSREVDRLLTNQKQSHFANAQPLQIE[SEQID508] Q9M3X6(Pea) >gi|164512526|emb|CAP06312.1|cvc[Pisumabyssinicum] MATTVESRFPLLLFPGIIFLASVCVTYANYDEGSETRVPGQRERGRQEGEKEEKRHGEWRPSYEKEEDEEEKQKYRYQREKEDEEEKQKYRYQR EKKEEKEVQPGRERWEREEDEEQVDEEWRGSQRRQDPEERARLRHREERTKRDRRHKREGEEEERSSESQEQRNPFLFKSNKFLTLFENENG HIRRLQRFDKRSDLFENLQNYRLVEYRAKPHTIFLPQH1DADLILVVLNGKAILTVLSPNDRNSYNLERGDTIKIPAGTTSYLVNQDDEEDLRVVD FVIPVNRPGKFEAFGLSENKNQYLRGFSKNILEASLNTKYETIEKVLLEEQEKKPQQLRDRKRRQQGGERDAIIKVSREQIEELRKLAKSSSKKSLPS EFEPFNLRSHKPEYSNKFGKLFEITPEKKYPQLQDLDILVSCVEINKGALMLPHYNSRAIVVLLVNEGKGNLELLGLKNEQQEREDRKERNNEVQ RYEARLSPGDVVIIPAGHPVAISASSNLNLLGFGTNAENNQRNFLSGSDDN[SEQID509] >gi|164512538|emb|CAP06318.1|cvc[Lathyrusannuus] MATTIKSRFPLLLLLGIIFLASVCVTWANYDEGSEPRVPGQRERGRQEGEKEEKRHGEWRPSYEEEYDEGLEPKVPGKRERGRQEGEKEEKRHE EWRPSYEKEEDEEEKQKYNYQREKKEHKEVQPGRERWERKQDEKQVEEDEEPGEEQWRGSKRHEDPEERARLRHREEKTKSYVEDNEETSS KEGRNPFLFKSNKFLTLFENENGHIRRLQRFDERSDIFENLQNYRLVEYRAKPHTMFLPQHIDADLILVVLNGKAILTVLSPNDRNSYNLERGDTV KLPAGTTSYLVNQDDEEDLRVVDLAIPVNRPGKFEAFGLSANKNQYLRGFSKNILEASLNTKYETIEKVLLEERRDQKGRQQGQETNAIVKVSRE QIEELRKLAKSSSKKSLLSESEPLNLRSQNPKYSNKFGKFFEITPQKKYPQLQDLDVSISCVEINKGALLLPHYNSRSIGILLVNEGKGNLELVGFKNE QQRQRENEETNKKLQRYEARLSSGDVVVIPEGHPVAISASSNLNLLGFGINAANNQRNFLTGSDDN[SEQID510] >gi11645125581embICAP06328.11cvc[Viciavillosa] MA-MKSRFPVLLLLGIIFLTSVCVTYANYDEGREPSVPGQRERGRQEGEKEEKRHGEWRPSEEDEEEKYKYEEGRVPGQRERGRQEGEKEEKR HGKWRPSEEEDEEEKYRYEEGSEPRGPGQRETGRQEGEKEKQRPEREPSYEKEEDEEEKQKYQYHREKKEQREVRPGRERFERHEDEEQWRG IQRHEDPEERARERYRAEIAKRQVEEEREERDIPHEREQRNPFLFKSNKFQTLFQNENGYIRRLQRFDKRSDLFENLQNYRLVEYRAKPHTIFLPQ HIDADLIIVVLSGRAILTVLSPDDRNSYNLERGDTIKLPAGTTSYLVNQDDEEDLRVVDLAIPVNRPGKVESFLLSGNKNQYLRGFSKNILEASFNT NYETIERVLLEEQDKESQQSIGQKRRSQRQETNALVKVSREQLEDLKRLAKSSSQEGLSSQFEPINLRSQNPKYSNKFGKVFEITPEKKYPQLQDL DLFVSSVDIKEGALMLPHYNSRAIVVLLVNEGRGNLELVGLKNEQQEQREKEDEQQERNNQVQRYEARLSPGDVVIIPAGHPVAVRASSDLNL LAFGINAENNQRNFLAGSDDN[SEQID511] P09918(Pea) >gi|357454557|ref|XP_003597559.1|Seedlipoxygenase-3[Medicagotruncatula] >gi|355486607|gb|AES67810.1|seedlinoleate95-lipoxygenase[Medicagotruncatula] MFSGVTGILNRGHKIKGTVVLMRKNVLDINSLTSVGGVIGQGFDILGSTLDNLTAFLGRSVSLQLISATKPDANGKGKLGKATFLEGIITSLPTLG AGQSAFKIHFEWDDDMGIPGAFYIKNFMQTEFFLVSLTLEDIPNHGSIYFVCNSWIYNAKHHKLDRIFFANKAYLPSETPAPLVHYREEELNNLR GDGTGERKEWERIYDYDVYNDLGNPEKGDNHARPVLGGSDTYPYPRRGRTGRKPNPKDPKSESRSDFVYLPRDEAFGHLKSSDFLTYGLKAVS QNVVPALESVIFDLNFTPNEFDSFDEVHGLYEGGIKLPTDVLSKISPLPVLKEIFRTDGEQFLKYPPPKVLQVSRSAWMTDEEFAREMLAGVNPN VICCLQEFPPRSKLDSQVYGDHTSKITKEHLEPNLEGLTVEEAIQNKKLFLLDHHDSIMPYLRRINSTPTKAYATRTILFLSSDKTLKPLAIELSLPHP DGDEHGAVSHVYQPALEGVESTIWLLAKAYVVVNDSCYHQLVSHWLNTHAVVEPFVIATNRHLSYLHPIYKLLYPHYRDTMNINSLARQSLVN DGGIIEKTFLWGRYSMEMSSKVYKNWTLPGQALPADLIKRGMAIEEPSSPCGVKLVVEDYPYAHDGLEIWAAIKTWVQDYVSLYYTTDDILRQ DSELQAWWKELVEVGHGDKKNEPWWPKMQAREELVEVCTTVIWIASALHAAVNFGQYSYGGLILNRPTLSRRFMPEKGSAEYNELVKSPQ KAYLKTITPKFQTLIDLSVIEILSRHASDEVYLGERDNPNWTSDTRALEAFKKFGNKLAEIEKNLAQRNNDEKLRHRLGPVQMPYTLLHPSSEEGL TFRGIPNSISI[SEQID512] >gi|734403888|gb|KHN32710.1|Seedlinoleate95-lipoxygenase-3[Glycinesoja] MLGGLLHRGHKIKGTVVLMRKNVLDVNSVTSVGGIIGQGLDLVGSTLDTLTAFLGRSVSLQLISATKADANGKGKLGKATFLEGIITSLPTLGAG QSAFKINFEWDDGSGIPGAFYIKNFMQTEFFLVSLTLEDIPNHGSIHFVCNSWIYNAKLFKSDRIFFANQTYLPSETPAPLVKYREEELHNLRGDG TGERKEWERIYDYDVYNDLGDPDKGENHARPVLGGNDTFPYPRRGRTGRKPTRKDPNSESRSNDVYLPRDEAFGHLKSSDFLTYGLKSVSQN VLPLLQSAFDLNFTPREFDSFDEVHGLYSGGIKLPTDIISKISPLPVLKEIFRTDGEQALKFPPPKVIQVSKSAWMTDEEFAREMLAGVNPNLIRCL KDFPPRSKLDSQVYGDHTSQITKEHLEPNLEGLTVDEAIQNKRLFLLDHHDPIMPYLRRINATSTKAYATRTILFLKNDGTLRPLAIELSLPHPQGD QSGAFSQVFLPADEGVESSIWLLAKAYVVVNDSCYHQLVSHWLNTHAVVEPFIIATNRHLSVVHPIYKLLHPHYRDTMNINGLARLSLVNDGG VIEQTFLWGRYSVEMSAVVYKDWVFTDQALPADLIKRGMAIEDPSCPHGIRLVIEDYPYAVDGLEIWDAIKTWVHEYVFLYYKSDDTLREDPEL QACWKELVEVGHGDKKNEPWWPKMQTREELVESCAIIIWTASALHAAVNFGQYPYGGLILNRPTLSRRFMPEKGSAEYEELRKNPQKAYLKT ITPKFQTLIDLSVIEILSRHASDEVYLGERDNPNWTSDTRALEAFKRFGNKLAQIENKLSERNNDEKLRNRCGPVQMPYTLLLPSSKEGLTFRGIP NSISI[SEQID513] >gi|593700103|ref|XP_007150490.1|hypotheticalproteinPHAVU_005G157000g[Phaseolusvulgaris] >gi|561023754|gb|ESW22484.1|hypotheticalproteinPHAVU_005G157000g[Phaseolusvulgaris] MFSGVSGLINRGHKLKGTVVLMRKNVLDVNSVTSVGGIVGQGLDILGSTVDNLTAFLGRSVSLQLISATKPDANGKGKLGKATFLEGIITSLPTL GAGQSAFKIHFEWDDEMGIPGAFYIKNFMQTEFYLVSLTLEDIPNHGSLHFLCNSWIYNAKHFKNDRIFFVNQIYLPSETPAPLVKYREEELVN MRGDGTGERKEWDRIYDYDVYNDLGDPDKGENNARPILGGSDTLPYPRRGRTGRRPTRKDPKSESRSSDIYLPRDEAFGHLKSSDFLTYGLKS VSQNFLPALQSAFDLNFTPNEFDSFEEVHGLYSGGIKLPTDVLSKISPLPVLKEIFRTDGEQTLKFPPPKVVQDSKSAWMTDEEFAREMICGVNP NLIRLLQDFPPQSKLDSQVYGDHTSQITKENLEPNLEGLTVDEAIQSKRLFLLDHHDSIMPYLRRINATSSKAYATRTILFLKKDRTLKPLAIELSLP HPGGDKSGVVSQVFLPADEGVESSVWLLAKSYVIVNDSSYHQLVSHWLNTHAVVEPFVIATNRHLSVVHPIYKLLHPHYRDTMNINALARGD LVNHGGIIEKTFVWGRYSMEMSAVIYKDWVFTDQALPADLIKRGIATEDPECPHGLRLFIEDYPYAVDGLEIWDAIKTWVHEYVFLYYKSDDTL KEDPELQAWWKELVEVGHGDKKNEPWWPKMQTREELVEACSIVIWTASALHAAVNFGQYPYGGLILNRPTLSRRFMPEEGSAEYEELKKSP QKALLKTITPKFQTLVDLSVIEILSRHASDEVYLGERDNPNWTSDTRALEAFKRFGKKLSEIEKKLSQRNNDEKLRNRYGPVMMPYTLLFPSSDE GLTFRGIPNSISI[SEQID514] P02857(Pea) >gi|483449|emb|CAA83677.1|leguminA[Viciasativa] MAKLLALSLSFCFLLFSSCFALREQSQQNECQLERINALEPDNRIESEGGLIETWNPNNRQFRCARVALSRATLQRNALRRPYYSNAPQEIYIQQ GNGYFGMVFPGCPETHEEPQQSEQGEGRRYRDSHQKVNRFREGDIIAVPTGIAFWMYNDQDTPVIAISLTDTGSSNNQLDQMPRRFYLAG NQEQEFLRYQHQQGGKQEQDNDGNNIFSGFKRDFLEDAFNVNRHIVDRLQGRNEDEEKGAIVKVKGGLSIIAPPERQARHERGSRQEEDED EKEERQPSHHKSRRDEDEDDKEKRHSQKGQSRRQGDNGLEETVCTAKLRANIGSSPSPDIYNPQAGRIKTVTSLDLPVLRWLKLSAEHGSLHK NAMFVPHYNLNANSVIYALKGRARLQVVNCNGNTVFDGELEAGRALTVPQNYAVAAKSLSERFTYVAFKTDDRASIARLAGTSSVIDDLPLDV VAATFNMQRNEARQLKSNNPFKFLVPPRQSEMRASA[SEQID515] >gi|600108|emb|CAA86824.1|leguminAprecursor[Vicianarbonensis] MAKLLALSLSLCFLLFSNSFALREQSQQNECQLERLDALEPDNRIESEGGLIETWNPNNRQFRCAGVALSRVTLQRNALRRPYYSNAPQEIYIQQ GNGYFGVVFPGCPETFEEPQESEQRERRRYRDSHQKVNRFREGDIIAVPTGNVLWMYNDQDTPVIAISLTDTGSSNNQLDQIPRRFYLAGNQ EQEFLRYQREQGGKQEQENDGNNIFSGFKRDFLEDALNVNRHIVDRLQGRNEDEEKGAIVKVKGGLSIITPPERQRGSRQEEDEDEKEERQPS RRRDESQKGESRRHGDNGLEETVCTAKLRVNIGSSPSPDIYNPQAGRINTVTSLDLPVLRWLKLSAEHGSLRKNALIVPHYNRNANSVIYALKG RARLQVVNCNGNTVFDGELEAGRALTVPQNYAVAAKSLSERFTYVAFKTNDRDGIARLAGTSSVINDLPLDVVAATFNLQRNEARQLKSNNPF KLLVPPRESEKRASA[SEQID516] >gi|502110016|ref|XP_004493779.1|PREDICTED:legumin-like[Cicerarietinum] MAKLLALSLSFCFLLFGSCFALRDQPEQNECQLEHLNALEPDNRIKSEGGLIETWNPSNKQFRCAGVALSRATLQPNSLRRPFYTNAPQEIFIQQ GNGYFGMVFPGCVETFEEPRESEQGEGSKFRDSHQKVNRFREGDIIAVPTGVVFWMFNDQDTPVIAVSLIDTSSFQNQLDQMPRRFYLAGN HEXXXXXXXXQQEGSEEEENEGGNIFSGFKRDFLEDALNVNRRIVNKLQGRNEDEEKGAIVKVKGGLSIITPPEKEPRQKRGSRQEEDEDEDEK RQPHRHSRQDEDEDEKRQPRRHSRGGSKSQRDNGFEETICTARLHQNIGSSSSPDIYNPQAGRIKTVTSFDLPALRFLKLSAEFGSLHKNAMFV PHYNLNANSILYALKGRARLQIVNCKGNSVFDGELEAGRALIVPQNFAIAAKSLSDRFSYVAFKTNDRAAIGRLLGASSLINGMPEEVVAAAFN MERNEARQLKFNSPFSFLVPPRSDSDNKAAA[SEQID517] P02855(Pea) >gi|164512536|emb|CAP06317.1|cvc[Lathyrushirsutus] MAIIIKSRFPLLLLLGIIFLASVCATWANYDEGSEPRVPGQRERGRQEGEKAEKSHEKWRPSYEEEYDEGSEPRVPGKRERGRQEGEKEEKRHGE WRPSHEEEYDEGSEPRVPTHGERGRQEGEKEEKRHEEWRPSYEKEEDEEEKEKYKYQREKKEQKEVQPGREKWERKQDEKHVEEDEDQEEE QWRGSKRREDPEERARLRYREERTKSNVEEETEERRNPFLFKSNKFLTLFENENGHIRRLQRFDERSDIFENLQNYRLVEYKAKPHTMFLPQHID ADLIIVVLNGKAILTVLSPNDRNSYNLERGDTIKLPAGTTSYLVNQDDEEDLRVVDLAIPVNRPGKFEAFGLSANKNQYLRGFSKNILEAFLNTKY ETIEKVLLEEQERRDRKGRQQGQETNAIVKVSREQIEELRKLAKSSSKKSLLSESEPINLRSQNPKYSNKFGKLFEITPEKKYPQLQDLDVSISCVEI NEGAPLLPHYNSRAIVLLLVNEGKGNLELVGFKNEQQRQRENEERNKKVQRYEARLSPGDVVVIPAGHPVAISASLNLNLVGFGVNAENNQR NFLTGSDDN[SEQID518 >gi|164512542|emb|CAP06320.1|cvc[Lathyruscicera] MATIIKSRFPLLLLLGIIFLASVCVTLANYDEGSEPRVPAQRERGRQEGEKEEKRHGEWRPSHEKEYDEGSEPRVPGRRERGRQEGEKEEKRHGE WRPSYEKEYDEGSEPRVPGRRERGRQEGEKEEKRHGEWRPSYEKEYDEEEKQKYQYEREKEEQKEVQPGRERWERKEDEEKEEDQWRGSQ RHEDPEERARLRYRKERTKKYVEEDTEETSSESQGRRNPFLFKSNKFLTLFENENGYIRRLQRFDERSDIFENLQNYRLVEYRAKPHTIFLPQHIDA DLILVILNGKAILTVLSPNDRNSYNLERGDTIKLPAGTTSYLVNEDDEEDLRVVDLVIPVNRPGKFEAFDLNQYLGGFSKSVLEASLNTKYETIEKVL LEEQQKQGQETNAIVKVSREQIEELRKLAKSSSKKSLLSELEPVNLRSHSPKYSNKFGKFFEITPEKKYPQLQDLDVSISCVEINEGALLLPHYNSRA IVVVLVNEGKGNLELLGVQNEDEQQERKERNKEVQRYEARLSPGDVVIIPSGHPVAVSASSNLNLLGFGINAENNQRNFLSGSDDN[SEQID519] >gi|164512544|emb|CAP06321.1|convicilin[Lathyrussativus] MATIIKSRFPLLLLLGIIFLASVCVTYANYDEGSEPRVPAQRERGRQEGEKEEKRHGEWRPSSEKEYDEGSEPRVPGRRERGRQEGEKEEKRHGE WRPSYEKEYDEEEKQKYQYEREKKEQKEVEPGRERWERKEDEEKEEDQWRGSQRHEDPEERARLRYRKERTKKYVEEDTEETSSESQGRRNP FLFKSNKFLTLFENENGYIRRLQRFDERSDLFENLQNYRLVEYRAKPHTIFLPQHIDADLILVILNGKAILTVLSPNDRNSYNLERGDTIKLPAGTTS YLVNEDDEEDLRVVDLVIPVNRPGKFEAFDLNQYLGGFSKSVLKASLNTKYETIEKVLLEEQQKQGQETNAIVKVSREQIEELRKLAKSSSKKSLLS ELEPVNLRSHSPKYSNKFGKFFEITPEKKYPQLQDLDVSISCVEINEGALLLPHYNSRAIVVLLVNEGKGNLELLGVQDEDEQQERKKRNKEVQRY EARLSPSDVVIIPAGHPVAVSASSNLNLLGFGINAENNERNFLSGSDDN[SEQID520] D3VNE1(Pea) >gi|357507721|ref|XP_003624149.1|Provicilin[Medicagotruncatula] >gi|87162569|gb|ABD28364.1|Cupin,RmlC-type [Medicagotruncatula]>gi|355499164|gb|AES80367.1|vicilin47kDaprotein[Medicagotruncatula] MAIKAPFQLLMLLGIFFLASVCVSSRDDRHDQENPFFFNANHFQTLFENENGHIRLLQRFDKRSKIFENLQNYRLLEYHSKPHTLFLPQHNDAD FlLAVLSGKAILTVLNPDNRNSFNLERGDTIKLPAGSIAYLANRDDNEDLRVLDLAIPVNRPGKFQSFSLSGSQNQQSFFSGFSKNILEAAFNANY EEIERVLIEEHEQEPQHRRGLRKDRRQQSQDSNVIVKVSREQIEELSRHAKSSSRRSGSSESAPFNLRSREPIYSNEFGNFFEITPEKNPQLKDLDIL VNYAEIREGSLLLPHFNSRATVIVVVDEGKGEFELVGQRNENQQEQREEDEQQEEERSQQVQRYRARLSPGDVYVIPAGHPTVVSASSDLSLL GFGINAENNERNFLAGEEDNVISQIERPVKEVAFPGSAQDVESLLKNQRQSYFANAQPQQREREEGRSQRQRELISSILGVF[SEQID521] >gi|164512560|emb|CAP06329.1|convicilin[Viciaperegrina] MATTFKSRFSLLLLLGIIFLAFVCVTCANYDEGSEPRVPGQRERGRQEGEKEEQSRERHPQREPSREKEEDEEEKQKYDEGTEPRVPGQRERGR QEGEKEEQRRERHPGQREPSQEEDEEREESDRRQEGSSKSEEQRNPFLFKSNKFLTLFQNGNGHIRLLQRFDKRSDLFENLQNYRLLEYRAKPH TIFLPQHIDADLILVVLSGRAILTVLSPDDRNSYNLERGDTIKLPAGTTSYPLNQDDEEDLRVVDLAISVNRPGKVESFNLSGNKNQYLRGFSENIL EASFNTKYETIEKVLLEEQDKESQQPRGQRLQRQETNALVKVSREQVEELKRLARTSSKKGVSSEFEPFNLRSHGPKYSNKFGKFFEITPEKKYPQ LQDLDISVSSVEINEGALFLPHYNSRAIVVVLVDEGKGNLELVGFKNEQQEQREKEDEQEERNKQVQRYEAKLSPGDVVIIPAGHPVAVSASSN LNLLGFGINAENNQRNFLTGSDDN[SEQID522] >gi|164512562|emb|CAP06330.1|convicilin[Vicialutea] MATTIKLRFPLLLLLGVILLASVCVTCANYDEGSEPRVPGRPEGEKEEKHRGKLRPSYEKEEDEGEKQRYHYEKKEQKEAQPRREKKEQKEEEKQ VEEESRESQRYEDPGERARERYRAEIIKRQVEKEREERDRRHQREGEEEEGSSKSRNPFLFKSNNFLTLFENENGHIRLLQRFDKRSDLFENLQNY RLVEYRAKPHTIFLPQHIDADLILVVLSGKAILTVLSPNNRNSYNLKRGDTIKLPAGTTSYLLNSDDEEDLRMVDLAISVNRPGKVESFNLSGNKN QYLRGFSKNILEASFNTKYETIEKVLLEEQDKESQQSIGQKRISQRQETNALVKVSREQIEEPKRLARSSSRKGVSSEFEPINLRSQRPKYSNKFGKF YEISPEKKYPQLQDLDVSVSSVEINEGALLLPHYNSRAIVTVLVNEGKGNLELIGFQNEQQGQREKEDEQQHERNKQVQRYDARLSSGDVVIIP AGHPVAVSASSNLDLLGFGINAENSQRNFLTGSDDN[SEQID523] P07728(Rice) >gi|531874314|gb|AGT59174.1|glutelin,partial[OryzasativaIndicaGroup] CRFDRLQAFEPIRSVRSQAGTTEFFDVSNEQFQCTGVSAVRRVIEPRGLLLPHYTNGASLVYIIQGRGITGPTFPGCPESYQQQFQQSGQAQLT ESQSQSHKFKDEHQKIHRFRQGDVIALPAGVAHWCYNDGEVPVVAIYVTDLNNGANQLDPRQRDFLLAGNKRNPQAYRREVEERSQNIFSG FSTELLSEALGVSSQVARQLQCQNDQRGEIVRVEHGLSLLQPYASLQEQEQGQVQSRERYQEGQYQQSQYGSGCSNGLDETFCTMKVRQNI DNPNRADTYNPRAGRVTNLNTQNFPILNLVQMSAVKVNLYQNALLSPFWNINAHSVVYITQGRARVQVVNNNGKTVFNGELRRGQLLIIPQ HYAVVKKAQREGCAYIAFKTNPNSMVSHIAGKSSIFRALPNDVLANAYRISREEAQRLKHNRGDEFGAFTPIQYKSYQDVYNAAESS[SEQID 524] >gi|109894635|gb|ABG47337.1|glutelinprecursor[Zizanialatifolia] MNMATINGPTIFFTVCLFLLCHGSLAQLLGQSTSQWQSSHRGSSRQCRFDRLQAFEPVRSVRSQAGTTEFFDASNELFQCAGVSIVRRIIEPRG LLLPQYTNGATIMYIIQGRGITGQTFPGCPESYQQQFQQSMQAQLTGSQSQSQKFKDEHQKINRFRQGDVIALPAGVAHWCYNDGEVPVVA IYVIDINNAANQLDPRQRDFLLAGNMRSPQAYRREVENQSQNIFSGFSAELLSEALGISTGVARQLQCQNDQRGEIVRVEHGLSLLQPYASLQE QEQKQEQPRERYQVTQHQQSQYGGGCSNGLDETFCAMRIWQNIDNPNLADTYNPRAGRVTNLNSQKFPILNLIQMSAVKVNLYQNALLSP FWNINSHSVVYVTQGCARVQVVNNNGKTVFNGELRRGQLLIIPQHYVVVKKAQREGCAYIAFKTNPNSMVSHIVGKSSIFRALPTDVLANAY RISREDAQRLKHNRGDELGAFTPLQYKSYQDVSSVAASS[SEQID525] >gi|472867|emb|CAA52764.1|11Sglobulin[Avenasativa] MATTSFPSMLFYFCIFLLFHGSMAQLFGQSSTPWQSSRQGGLRGCRFDRLQAFEPLRQVRSQAGITEYFDEQNEQFRCTGVSVIRRVIEPQGL VLPQYHNAPALVYILQGRGFTGLTFPGCPATFQQQFQPFDQSQFAQGQRQSQTIKDEHQRVQRFKQGDVVALPAGIVHWCYNDGDAPIVA IYVFDVNNNANQLEPRQKEFLLAGNNKREQQSGNNIFSGLSVQLLSEALGISQQAAQRIQSQNDQRGEIIRVSQGLQFLKPIVSQQVPGEQQV YQPIQTQEGQATQYQVGQSTQYQVGKSTPYQGGQSSQYQAGQSWDQSFNGLEENFCSLEARKNIENPQHADTYNPRAGRITRLNSKNFPIL NIVQMSATRVNLYQNAILSPFWNINAHSVIYMIQGHARVQVVNNNGQTVFNDILRRGQLLIVPQHFVVLKKAEREGCQYISFKTNPNSMVSH IAGKSSILRALPIDVLANAYRISRQEARNLKNNRGEEFGAFTPKLTQKGFQSYQDIEEGSSSPVRASE[SEQID526] P14614(Rice) >gi|115445309|ref|NP_001046434.1|Os02g0248800[OryzasativaJaponicaGroup] >gi|37993738|gb|AAR06952.1| glutelintype-B[OryzasativaJaponicaGroup]>gi|47497729|dbj|BAD19794.1| glutelintype-B[OryzasativaJaponica Group]>gi|113535965|dbj|BAF08348.1|Os02g0248800[OryzasativaJaponicaGroup] >gi|215768942|dbj|BAH01171.1| unnamedproteinproduct[OryzasativaJaponicaGroup]>gi|284431772|gb|ADB84627.1| glutelin[OryzasativaJaponicaGroup] MTISVFSRFSIYFCVLLLCNGSMAQLFDPATNQWQTHRQGSFRECRFERLQAFEPLQNVRSEAGVTEYFDETNELFQCTGTFVIRRVIQPQGLL IPRYANTPGMVYIIQGRGSMGLTFPGCPATYQQQSQQFLFQGESQSQKFIDEHQKIHQFRQGDIVVLPTGVAHWFYNDGDTPVVALYVYDI NNSANQLEPRHREFLLAGKNNRVQQVYGRSIQQHSGQNIFNGFSVEPLSEALN1NTVTTKRLQSQNDQRGEIIHVKNGLQLLKPTLTQRQEQE QAQYQEVQYSEKPQTSSRWNGLEENLCTIKTRLNIENPSRADSYDPRAGRITSLDSQKFPILNIIQMSATRVNLYQNAILTPFWNVNAHSLMYV IRGRARVQVVSNFGKTVFDGVLRPEQLLIIPQNYVVLKKAQHEGCQYIAINTNANAFVSHLAGVDSVFHALPVDVIANAYCISREEARRLKNNR GDEYGPFPPRLQQQIYPEFSNESKGETSE[SEQID527 >gi|428674402|gb|AFZ41188.1|glutelin,partial[OryzasativaJaponicaGroup] LLCHGSMAQIFSLGINPWQNPRQGGSRECRFDRLQAFEPLRKVRHEAGVTEYFDEKNEQFQCTGTLVIRRIIEPQGLLLPRYSNTPGLVYIIQGT GVLGLTFPGCPATYQKQFRHFGLEGGSQRQGKKLRDENQKIHQFRQGDVVALPSGIPHWFYNEGDTPVVALFVFDVNNNANQLEPRQKEFL LAGNNIEQQVSNPSINKHSGQNIFNGFNTKLLSEALGVNIEVTRRLQSQNDRRGDIIRVKNGLRLIKPTITQQQEQTQDQYQQIQYHREQRSTS KYNGLDENFCAIRARLNIENPNHADTYNPRAGRITNLNSQKFSILNLVQMSATRVNLYQNAILSPFWNINAHSLVYTIQGRARVQVVSNHGKA VFNGVLRPGQLLIIPQNYVVMKKAELEGFQFIAFKTNPNAMVNHIAGKNSVLRAMPVDVIANAYRISRQEARSLKNNRGEEIGAFTPRYQQQ KIHQEYSNPNESETQ[SEQID528] >gi|226510|prf|11515394Aseedstorageglobulin MATTRFPSLLFYSCIFLLCNGSMAQLFGQSFTPWQSSRQGGLRGCRFDRLQAFEPLRQVRSQAGITEYFDEQNEQFRCAGVSVIRRVIEPQGLL LPQYHNAPGLVYILQGRGFTGLTFPGCPATFQQQFQPFDQARFAQGQSKSQNLKDEHQRVHHIKQGDVVALPAGIVHWCYNDGDAPIVAV YVFDVNNNANQLEPRQKEFLLAGNNKREQQFGQNIFSGFSVQLLSEALGISQQAAQKIQSQNDQRGEIIRVSQGLQFLKPFVSQQGPVEHQA YQPIQSQQEQSTQYQVGQSPQYQEGQSTQYQSGQSWDQSFNGLEENFCSLEARQNIENPKRADTYNPRAGRITHLNSKNFPTLNLVQMSA TRVNLYQNAILSPYWNINAHSVMHMIQGRARVQVVNNHGQTVFNDILRRGQLLIIPQHYVVLKKAEREGCQYISFKTTPNSMVSYIAGKTSIL RALPVDVLANAYRISRQESQNLKNNRGEEFGAFTPKFAQTGSQSYQDEGESSSTEKASE[SEQID529] P07730(Rice) >gi|225959|prf|11404367Aglutelin MASTNRPIVFFTVCLFLLCDGSLAQQLLGQSTSQWQSSRRGSPRGCRFDRLQAFEPIRSVRSQAGTTEFFDVSNELFQCTGVSVVRRVIEPRGL LLPHYTNGASLVYIIQGRGITGPTFPGCPETYQQQFQQSGQAGLTESQSQSHKFKDEHQKIHRFRQGDVIALPAGVAHWCYNDCEVPVVAIYV TDINNGANQLDPRQRDFLLAGNKRNPQAYRREVEEWSQNIFSGFSTELLSEAFGISNQVARQLQCQNDQKGEIVRVERGLSLLQPYASLQEQ EQGQMQSREHYQEGGYQQSQYGSGCPNGLDETFCVNKVRQNIDNPNRADTYNPRAGRVTNLSQNFPILNLVQMSAVKVNLYQNTDTWIS MGQEENALLSPFWNINAHSIVYITQGRAQVQVLRRGQLLIVPQHYVVVKKAQREGCAYIAFKTNPNSMVSHIAGKSSIFRALPTDVLANAYRIS REEAQRLKHNRGDEFGAFTPLQYKSYQDVYNVAESS[SEQID530] >gi|573943558|ref|XP_006654150.1|PREDICTED:glutelintype-A3-like[Oryzabrachyantha] MKSSIVFSTICLVLLCHGSLAQLLSQSTSQWQSSRRGSPRQCRFDQLQAFEPIRTVRSQAGVTEFYDVSNELFQCTGVSVVRRVIEPRGLLLPHY SNGATLVYIIQGRGITGPTFPGCPETYQQQFQQSGEAQPFEGQSHKFRDEHQKIHRFRQGDVVALPAGVAHWCYNDGEVPIVAIYVTDIYNS ANQLDPRHRDFFLAGNNKVAQQLYRSEARENSKNIFGGFSVELLSEALGISRGVARQLQCQNDQRGEIVRVEHGLALLQPYASVQEQQQEQV QSRDYEQTQYQQKQPQGSCSNGLDETFCTMRLRQNIDNPNLADTYNPKAGRITYLNGQKFPILNLVQMSAVKVNLYQNAVLSPFWNINAHS VVYITQGRARVQVVNNNGKTVFDGELRQGQLLIIPQHHVVLKKAQREGCSYIALKTNPNSIVSHIAGKNSIFRALPGDVVTNAYRISREEAKRIK HNRGDESGVFAPSHAYRSYQDMSVAA[SEQID531] >gi|721641733|ref|XP_010231907.1|PREDICTED:12Sseedstorageglobulin1-like [Brachypodiumdistachyon] MAHTSFSSFLSYFCLFLLFHGSMAQVLGQVSTWQSSRQGGSRDCSFDRLQAIEPVTQVRSQAGLTEYFDEQNEQFRCAGVFVIRRVIEPRGLL LPRYHNTPGLVYILQGNGFVGLTFPGCPETFREQFQQFRQTQSTLGQSQCQSQKLGDVHQRVHQFTQGDVVALPTGVAHWIYNGGDAPVV IVYVFDVNNNANQLEPRQKEFLLGGNYNGVLQYGQNIFSGFNAQLLSQAFGINEQTSQRIQNQNDGRGDIIRVDNGLQFLKPVVTQQQPEQ PFMPIQHQTGQSSRNGLEENFCSLEPRQNIEDPNRADTYNPRAGSITRLNGQNFPILNLVQMSATRVNLQKNAILSPFWNINAHSVVYVIQG HALVQVVNNQGHNVFNGLLHRGQLLIIPQNYVVLKKAESEGYQYIAFKTNANSMVSHIAGKNSILRALPVDVIANAYRISRQEAQNLKNNRGE ETGVLTPNFSQSTCQSYQTEDVQSLRPMSHWSE[SEQID532] >gi|169244463|gb|ACA50505.1|seedallergenicproteinRAG2[OryzasativaJaponicaGroup] MASNKVVFSALLLIIVSVLAATATMADHHKDQVVYSLGERCQPGMGYPMYSLPRCRAVVKRQCVGHGAPGGAVIDEQLRQDCCRQLAAVID DSWCRCSALNHMVGGIYRELGATDVGHPMAXVFPGCRRGIDLERAAASLPAFCNVIDIPNGTGGVCYWLGYPRTPRTGH[SEQID533] >gi|5777592|emb|CAA44001.1|lowmolecularweightglobulin[Oryzasativa] MASNKVVFSALLLIIVSVLRRDGTMADHHKDQVVYSLGERCQPGMGYPMYSLPRCRAVVKRQCVGHGAPGAVDEQLRQDCCRQLAAVDD SWCRCSALNHMVGGIYRELGATDVGHPMAEVFPGCRRGDLERAAASLPAFCNVDIPNGTGGVCYWLGYPRTPRTGH[SEQID534] >gi|115471175|ref|NP_001059186.1|Os07g0214600[OryzasativaJaponicaGroup] >gi|23616954|dbj|BAC20657.1| allergenRA16[OryzasativaJaponicaGroup]>gi|113610722|dbj|BAF21100.1| Os07g0214600[OryzasativaJaponica Group]>gi|125557687|gb|EAZ03223.1|hypotheticalproteinOsl_25372[OryzasativaIndicaGroup] MASNKVVISALLVVVVSVLAATTTMADHHQEQVVYTPGQLCQPGIGYPTYPLPRCRAFVKRQCVAPGTVDEQVRRGCCRQLAAIDSSWCRC DALNHMLRI1YRESGAADAGHPMAEVFRGCRRGDIERAAASLPAFCNVDIPNGVGGVCYWLPGTGY[SEQID535] Q0DEV5(Rice) >gi|83375868|gb|ABC17777.1|waxy[Oryzarufipogon] MSALTTSQLATSATGFGIADRSAPSSLLRHGFQGLKPRSPAGGDATSLSVTTSARATPKQQRSVQRGSRRFPSVVVYATGAGMNVVFVGAEM APWSKTGGLGDVLGGLPPAMAANGHRVMVISPRYDQYKDAWDTSVVAEIKVADRYERVRFFHCYKRGVDRVFVDHPSFLEKVWGKTGEKI YGPDTGVDYKDNQMRFSLLCQAPRILNLNNNPYFKGTYGEDVVFVCNDWHTGPLASYLKNNYQPNGIYRNAKVAFCIHNISYQGRFAFEDYP ELNLSERFRSSFDFIDGYDTPVEGRKINWMKAGILEADRVLTVSPYYAEELISGIARGCELDNIMRLTGITGIVNGMDVSEWDPSKDKYITAKYD ATTAIEAKALNKEALQAEAGLPVDRKIPLIAFIGRLEEQKGPDVMAAAIPELMQEDVQIVLLGTGKKKFEKLLKSMEEKYPGKVRAVVKFNAPLA HLIMAGADVLAVPSRFEPCGLIQLQGMRYGTPCACASTGGLVDTVIEGKTGFHMGRLSVDCKVVEPSDVKKVAATLKRAIKVVGTPAYEEMV RNCMNQDLSWKGPAKNWENVLLGLGVAGSAPGIEGDEIAPLAKENVAAP[SEQID536] >gi|297614332|gb|AD148504.1|glycogensynthetase[Oryzaofficinalis] MSALTTSQLATSATGFGIADRSAPSSLLRHGFQGLKPRSPAGGDASSLSVTTSARATPKQQRSVQRGSRRFPSVVVYATGAGMNVVFVGAEM APWSKTGGLGDVLGGLPPAMAANGHRVMVISPRHDQYKDAWDTSVVAEIKVADRYERVRFFHCYKRGVDRVFIDHPSFLEKVWGKTGEKI YGPDTGVDYKDNQMRFSLLCQAALEAPRILNLNNNPYFKGTYGEDVVFVCNDWHTGPLPSYLKNNYQPNGIYRNAKVAFCIHNISYQGRFAF EDYPELNLSERFRSSFDFIDGYDTPVEGRKINWMKAGILESDRVLTVSPYYAEELISGIARGCELDNIMRLTGITGIVNGMDVSEWDPSKDKYIA AKYDATTAIEAKALNKEALQAEAGLPVDRKIPLIAFIGRLEEQKGPDVMAAAIPELMQENVQIVLLGTGKKKFEKLLKSMEEKYPGKVRAVVKF NAPLAHLIMAGADVLAVPSRFEPCGLIQLQGMRYGTPCACASTGGLVDTVIEGKTGFHMGRLSVDCKVVEPSDVQKVATTLKRAIKIVGTPAY NEMVRNCMNQDLSWKGPAKNWENVLLGLGVAGSAPGVEGEEIAPLAKENVAAP[SEQID537] >gi|389620054|gb|AFK93486.1|granule-boundstarchsynthase[Hordeumvulgaresubsp.vulgare] MAALATSQLATSGTVLGVTDRFRRPGFQGLRPRNPADAALGMRTIGASAAPKQSRKAHRGSRRCLSVVVRATGSGMNLVFVGAEMAPWS KTGGLGDVLGGLPPAMAANGHRVMVVSPRYDQYKDAWDTSVISEIKVADEYERVRFFHCYKRGVDRVFIDHPWFLEKVRGKTKEKIYGPDA GTDYEDNQQRFSLLCQAALEAPRILNLNNNPYFSGPYGEDVVFVCNDWHTGLLACYLKSNYQSNGIYRTAKVAFCIHNISYQGRFSFDDFAQL NLPDRFKSSFDFIDGYDKPVEGRKINWMKAGILQADKVLTVSPYYAEELISDEARGCELDNIMRLTGITGIVNGMDVSEWDPTKDKFLAVNYDI TTALEAKALNKEALQAEVGLPVDRKVPLVAFIGRLEEQKGPDVMIAAIPEILKEEDVQIILLGTGKKKFEKLLKSMEEKFPGKVRAVVRFNAPLAH QMMAGADLLAVTSRFEPCGLIQLQGMRYGTPCVCASTGGLVDTIVEGKTGFHMGRLSVDCNVVEPADVKKVATTLKRAVKVVGTPAYQEM VKNCMIQDLSWKGPAKNWEDVLLELGVEGSEPGIVGEEIAPLAMENVAAP[SEQID538] P14323(Rice) >gi|573918992|ref|XP_006647120.1|PREDICTED:glutelintype-B2-like[Oryzabrachyantha] MATTVFSRFSTYFCVLLLCHGSMAQLFNPSTNPWHNPRQGSSRECRFDRLQPFEPLRKVRSEAGVTEYFDEKNELFQCTGTFVIRRVIQPQGLL VPRYTNAPGLVYIIQGRGSIGLTFPGCPATYQQQFQQFLPQEQSQSQKFRDEHQKIHQFRQGDIVALPAGVAHWFYNDGDAPVVAVYVYDV KNSANQLEPRQREFLLGGNNMRAQQVYGSSAEQHSRQNIFSGFGVEILSEALGISTVTTKRLQSQNDQRGEIIHVKNGLQFLKPTLTQQQEQA QAQYQEVQYSEQQQTSSRWNGLDENFCTIKARMNIENTSRADTYNPRAGRTTSLNSQKFPILNLVQMSATRVNLYQNAILSTFWNVNAHSL VYTIQGRARVQVVSNFGKTVFDGELRPGQLLIIPQHYVVLKKAQREGFRYIAIKTNANAFVSQLVGKNSVFRSLPVDVIANVYRISREQARSLKN NRGEEHGAFAPRSQQQSYPGFSNQSESETSE[SEQID539] >gi|573919041|ref|XP_006647142.1|PREDICTED:glutelintype-B4-like[Oryzabrachyantha] MATTTFSRFSIYFCVLLLCHGSMAQLFSPTLNPWHSSRRGGSRDCRFDRLQAFEPLRRVRSEAGVTEYFDERNEQFQCTGTFVIRRVIEPQGLL VPRYTNTPGVVYIMQGRGSMGLTFPGCPATYQQQFQQFLPEGQSQSQKFRDEHQKIHQFRQGDIVALPAGVAHWFYNEGDTPVVALYVFD INNSANQLEPRQKDFLLAGNNNREQQVYGRSIEKHSGQN1FSGFNHELLSEALGISTLAAKRLQGQNDHRGEIIRVRNGLQLLKPTFTQQQEQ AQSQYQVQYSEKQQESTRCNGLDENFCTINARLNIENPSRADTYNPRAGRITHLNNQKFPILNLVQMSATRVNLYQNAILSPYWNVNAHSLV YMVQGHARVQVVSNLGKTVFNSVLRPGQLLIIPQHYVVLKKAEREGCQYIAFKTNANSIVSQLAGKNSILRAMPVDVVANAYRISREQARDLK NNRGEELGAFTPKFEQQSYPGLSNESESEASE[SEQID540] >gi|109894635|gb|ABG47337.1|glutelinprecursor[Zizanialatifolia] MNMATINGPTIFFTVCLFLLCHGSLAQLLGQSTSQWQSSHRGSSRQCRFDRLQAFEPVRSVRSQAGTTEFFDASNELFQCAGVSIVRRIIEPRG LLLPQYTNGATIMYIIQGRGITGQTFPGCPESYQQQFQQSMQAQLTGSQSQSQKFKDEHQKINRFRQGDVIALPAGVAHWCYNDGEVPVVA IYVIDINNAANQLDPRQRDFLLAGNMRSPQAYRREVENQSQNIFSGFSAELLSEALGISTGVARQLQCQNDQRGEIVRVEHGLSLLQPYASLQE QEQKQEQPRERYQVTQHQQSQYGGGCSNGLDETFCAMRIWQNIDNPNLADTYNPRAGRVTNLNSQKFPILNLIQMSAVKVNLYQNALLSP FWNINSHSVVYVTQGCARVQVVNNNGKTVFNGELRRGQLLIIPQHYVVVKKAQREGCAYIAFKTNPNSMVSHIVGKSSIFRALPTDVLANAY RISREDAQRLKHNRGDELGAFTPLQYKSYQDVSSVAASS[SEQID541] P29835(Rice) >gi|226508602|ref|NP_001152635.1|globulinprecursor[Zeamays]>gi|195658363|gb|ACG48649.1| globulinprecursor[Zeamays] MAKIAAAAAAAAALCFAALVAVAVCQGEVERQRLRDLQCWQEVQESPLDACRQVLDRQLTGGGVGGPFRWGTGLRMRCCQQLQDVSRE CRCAAIRSMVRGYEEAMPPLEKGWWPWGRQQQPPPQGGGGGQGGYYYPCSRAGEGYQTQMYPPCRPGTTGPRIGRVRLTKAREYAAGL PMMCRLSEPQECSIFSGGDQY[SEQID542] >gi|242090997|ref|XP_002441331.1|hypotheticalproteinSORBIDRAFT_09g024570[Sorghumbicolor] >gi|241946616|gb|EES19761.1|hypotheticalproteinSORBIDRAFT_09g024570[Sorghumbicolor] MAKIAAVAATAALCLAALVAVAVGQGVVERQRLKDLQCWQEVQENPLGACRQVLDRQLTGGMRYGIGPFRWGTGLRMRCCQQLQDVSR ECRCAAIRSMVRGYEETMPPLEKGWWGQQPQPGYDYPCSQAGEGYGYGESGQQQMYPPCRPGTGQKIARVKLTKARQYAAGMPMMCR LSEPQECSVFSGGDQYY[SEQID543] >gi|514748428|ref|XP_004961615.1|PREDICTED:19kDaglobulin-like[Setariaitalica] MAKFVVAAATAALCLAALVAMAAGQSGFERQRLRDLRCQREVEENPLWACRQVLDRQLTGGMRYGVGPFRWGTGLRMRCCQQLQDVS RECRCSAVRRMVRGYEEAMPPLEEGPYGYGGEQGEGYYGGGEGGEGYLPFPPRRIGRVRLTKARQYAAGLPMMCRLEPQECSVFSGDQYK [SEQID544] P0C1U8(Bacterial)GLUC(Staphylococcusaureus) >gi|446599182|ref|WP_000676528.1|glutamylendopeptidase[Staphylococcusaureus] >gi|253729369|gb|EES98098.1| trypsin[Staphylococcusaureussubsp.aureusTCH130]>gi|341844549|gb|EGS85761.1| glutamylendopeptidase [Staphylococcusaureussubsp.aureus21259]>gi|537390486|gb|AGU61109.1| Glutamylendopeptidaseprecursor [Staphylococcusaureussubsp.aureusCN1]>gi|564714561|gb|ETD14665.1| glutamylendopeptidase[Staphylococcus aureussubsp.aureusKPL1845]>gi|577466329|gb|EUG79766.1| glutamylendopeptidase[StaphylococcusaureusM0139] >gi|580560623|gb|EVF84961.1|glutamylendopeptidase[StaphylococcusaureusCoA56020] >gi|580687002|gb|EVH10169.1|glutamylendopeptidase[StaphylococcusaureusUCIM6080] >gi|751815683|gb|KIN24957.1|glutamylendopeptidase[StaphylococcusaureusMRSA_CVM43477] >gi|781884797|dbj|BAR08486.1|glutamylendopeptidaseprecursor[Staphylococcusaureussubsp.aureus] >gi|781887762|dbj|BAR11210.1|glutamylendopeptidaseprecursor[Staphylococcusaureussubsp.aureus] MKGKFLKVSSLFVATLTTATLVSSPAANALSSKAMDNHPQQSQSSKQQTPKIQKGGNLKPLEQREHANVILPNNDRHQITDTTNGHYAPVTYi QVEAPTGTFIASGVVVGKDTLLTNKHVVDATHGDPHALKAFPSAINQDNYPNGGFTAEQITKYSGEGDLAIVKFSPNEQNKHIGEVVKPATMS NNAETQVNQNITVTGYPGDKPVATMWESKGKITYLKGEAMQYDLSTTGGNSGSPVFNEKNEVIGIHWGGVPNEFNGAVFINENVRNFLKQ NIEDIHFANDDQPNNPDNPDNPNNPDNPNNPDEPNNPDNPNNPDNPDNGDNNNSDNPDAA[SEQID545]