ANHYDROUS AEROSOL COMPOSITION BASED ON PARTICLES ENCAPSULATING A BENEFICIAL AGENT

Abstract

The present invention relates to an anhydrous composition comprising: 1) at least particles releasing a beneficial agent comprising a core containing at least one beneficial agent and an envelope surrounding the core; said envelope comprising at least one hydrophobically modified polysaccharide and at least one water-soluble carbohydrate and/or water-soluble polyol;
said particles simultaneously having a poured powder density ranging from 300.0 g/l to 600.0 g/l and an absolute density of greater than 1.0 and 2) at least propellant.

The invention also relates to a cosmetic process for caring for and/or for the hygiene of and/or for conditioning and/or for fragrancing and/or for making up a keratin material, which consists in applying to said keratin material a composition as defined previously.

The invention additionally relates to a cosmetic process for treating body odor and optionally human perspiration, which consists in applying to a keratin material a composition as defined previously comprising at least one deodorant active agent and/or antiperspirant active agent in free form and/or in encapsulated form.

Claims

1. An anhydrous composition comprising: 1) at least particles comprising a core containing at least one beneficial agent and an envelope surrounding the core; said envelope comprising at least one hydrophobically modified polysaccharide and at least one water-soluble carbohydrate and/or water-soluble polyol; said particles simultaneously having a poured powder density ranging from 300.0 g/l to 600.0 g/l and an absolute density of greater than 1.0 and 2) at least one propellant.

2. The composition as claimed in claim 1, comprising a physiologically acceptable medium.

3. The composition as claimed in claim 1, in which the particles are spherical and, in particular have a number-mean diameter ranging from 1 to 30 m and a volume-mean diameter ranging from 5 to 150 m.

4. The composition as claimed in claim 1, in which the hydrophobically modified polysaccharide is chosen from celluloses and hydrophobically modified derivatives thereof, starches and hydrophobically modified derivatives thereof, guars and hydrophobically modified hydroxyethyl-, carboxymethyl- and hydroxypropyl-guar derivatives; hydrophobically modified dextrans; hydrophobically modified pullulans, hydrophobically modified inulins.

5. The composition as claimed in claim 1, in which the hydrophobically modified polysaccharide represents from 25% to 80% by relative to the total weight of the envelope of the particle.

6. The composition as claimed in claim 1, in which the water-soluble polyol is chosen from triols, tetraols, pentols, hexols, heptols, octaols and nonanols, and mixtures thereof.

7. The composition as claimed in claim 1, in which the water-soluble carbohydrate is chosen from water-soluble monosaccharides, water-soluble oligosaccharides and water-soluble polysaccharides.

8. The composition as claimed in claim 7, in which the monosaccharides are chosen from tetroses, pentoses, hexoses and heptoses; the oligosaccharides are chosen from diholosides, triholosides, glucose syrups and glucose-fructose syrups, and more particularly glucose syrups with a D.E. ranging from 21 to 60; the polysaccharides are chosen from dextrans, pullulans and maltodextrins.

9. The composition as claimed in claim 7, in which the water-soluble carbohydrate is chosen from water-soluble oligo- and polysaccharides.

10. The composition as claimed in claim 1, in which the water-soluble carbohydrate(s) and/or the water-soluble polyols represent from 20% to 75% by weight relative to the total weight of the envelope of the particle.

11. The composition as claimed in claim 1, in which the envelope of the particles with release of beneficial agent is formed from at least one starch (C.sub.5-C.sub.20)alkenyl succinate and from at least one maltodextrin with a D.E. ranging from 4 to 20 and/or a glucose syrup with a D.E. ranging from 21 to 60.

12. The composition as claimed in claim 11, in which the envelope of the particles with release of beneficial agent is formed from a) at least one starch (C.sub.5-C.sub.20)alkenyl succinate in an amount ranging from 25% to 80% by weight relative to the total weight of the envelope of the particle and b) at least one maltodextrin with a D.E. ranging from 4 to 20 and/or a glucose syrup with a D.E. ranging from 21 to 60, in an amount ranging from 20% to 75% by weight relative to the total weight of the envelope of the particle.

13. The composition as claimed in claim 1, in which the particles with release of beneficial agent may be obtained according to a process comprising at least the following steps: an aqueous solution formed from a mixture of the water-soluble carbohydrate and/or the water-soluble polyol and of the hydrophobically modified polysaccharide is prepared, the beneficial agent is then added and the whole is stirred so as to form an emulsion; and said emulsion thus formed is homogenized at high pressure at a pressure ranging from 10 to 200 bar; said emulsion is sprayed in a drying chamber; and the water is extracted for a time not exceeding 3 hours, with a fluid under pressure so as to obtain particles with release of beneficial agent.

14. The composition as claimed in claim 1, in which the beneficial agents are chosen from: (i) fatty substances; (ii) fragrancing substances; (iii) pharmaceutical active principles; (iv) cosmetic active agents.

15. The composition as claimed in claim 1, in which the beneficial agents are chosen from fragrancing substances.

16. The composition as claimed in claim 1, in which the particles comprise at least one or more fragrancing substances with a saturating vapor pressure at 25 C. of greater than or equal to 10.0 Pa and said fragrancing substance(s) represent from 50% to 100% by weight relative to the total weight of the fragrancing substances present in the particles.

17. The composition as claimed in claim 1, wherein a) the particles comprise at least one fragrancing substance and b) the composition also comprises at least one fragrancing substance in free form, which may be identical to or different from said fragrancing substance present in said particles.

18. The composition as claimed in claim 1, wherein it exclusively contains one or more fragrancing substances encapsulated in the particles.

19. The composition as claimed in claim 1, comprising at least one deodorant active agent and/or at least one antiperspirant active agent in free form and/or in encapsulated form.

20. An aerosol device formed from a container comprising a composition as defined and as claimed in claim 1 and from a means for dispensing said composition.

21. A cosmetic process for caring for and/or for the hygiene of and/or for conditioning and/or for fragrancing and/or for making up a keratin material, which comprises applying to said keratin material a composition as claimed in claim 1.

22. A cosmetic process for treating body odor and optionally human perspiration, which applying to a keratin material a composition as claimed in claim 19.

23. A consumer product, which is conditioned in an aerosol device formed from a container comprising a composition as claimed in claim 1 and from a means for dispensing said composition.

Description

EXAMPLE A

[0268] Capsules were prepared using the following composition:

TABLE-US-00001 Composition Hydrophobically Water-soluble Example A modified starch polysaccharide Fragrance* Water Amidon Capsul Potato maltodextrin 55 g 225 g from National MD 20 P from Starch Avebe 110 g 110 g *The perfume used has the following composition:

TABLE-US-00002 Ingredients Amount in g Isopropyl myristate 20.5 Methyl dihydrojasmonate 15 2-Phenylethanol 8 1-(1,2,3,4,5,6,7,8-Octahydro- 8 2,3,8,8-tetramethyl- 2-naphthyl)ethan-1-one Hexylcinnamal 6 Tetrahydro-2-isobutyl-4- 6 methylpyran-4-ol Hexyl salicylate 6 Benzyl acetate 5 1,4-Dioxacycloheptadecane- 5 5,17-dione 3-Methyl-5-phenyl-1-pentanol 5 Dihydromyrcenol 4 Orange terpenes 0.05% B H T 4 (limonene >95%) 2-Acetonaphthone 2 3a,6,6,9a- 1 Tetramethyldodecahydronaphtho[2,1- b]furan , -Dimethyl-p-ethylphenylpropanal 1 1,3-Benzodioxole-5-carboxaldehyde 1 2-Isopropyl-5-methylcyclohexanone 1 1-Phenylethyl acetate 0.8 2,6-Dimethylhept-5-enal (Melonal) 0.5 2,4-Dimethylcyclohex-3-ene-1- 0.2 carbaldehyde (Triplal)

Process for Preparing the Emulsion

[0269] Potato maltodextrin MD20 P and Amidon Capsul (sodium salt of starch octenyl succinate) were mixed in water until dissolved, the perfume was then added and the whole was emulsified with a Heidolph Diax 900 Ultra-Turrax disperser (motor power 900 W with an electronically controlled speed of 8000 to 26 000 rpm) at the maximum power for 4 minutes.

Drying Procedure for Obtaining Spherical Particles

[0270] The emulsion obtained was then homogenized at a pressure of 30 bar using a high-pressure pump and then sprayed in an atomization chamber using a nozzle simultaneously with a stream of CO.sub.2 (30 bar, 45 C.) which was circulated continuously at a flow rate of about 500 g/min to remove the water. The dried powder was retained on a filter located at the base of the atomization chamber, and then collected after depressurization. 270 g of spherical microcapsules are thus obtained in the form of a fine white powder with a number-mean diameter of 7.8 m and a volume-mean diameter of 47 m.

[0271] The particle size was measured via a dry route by laser scattering using a Microtrac S3500 particle size analyzer, the particle sizes being expressed by volume and by number.

TABLE-US-00003 Measured characteristics of the capsules Amount of Amount encapsulated of free Poured perfume perfume powder Absolute Example A (%) (%) density density 19.8 <0.1 484 1.12

EXAMPLES B TO H

[0272] According to the process described in Example A, the following capsules were prepared:

TABLE-US-00004 Composition Hydrophobically Perfume modified Water-soluble of starch polysaccharide Example A Water Example B Amidon Capsul Maltodextrin MD 55 g 225 g from National 120 from Tereos Starch 110 g 110 g Example C Amidon Capsul Maltodextrin MD 55 g 225 g from National 170 from Tereos Starch 110 g 110 g Example D Amidon Capsul Maltodextrin MD 55 g 225 g from National 190 from Tereos Starch 110 g 110 g Example E Amidon Capsul Potato maltodextrin 105 g 225 g from National MD 20 P from Starch Avebe 110 g 110 g Example F Amidon Capsul Potato maltodextrin 55 g 225 g from National MD 20 P from Starch Avebe 66 g 154 g Example G Amidon Capsul Potato maltodextrin 55 g 225 g from National MD 20 P from Starch 66 g Avebe 154 g Example H Amidon Capsul Glucose syrup 55 g 225 g from National Glucodry G290 Starch from Tereos 110 g 110 g

TABLE-US-00005 Measured characteristics of the capsules Amount Poured Amount of of free powder encapsulated perfume density Absolute Examples perfume (%) (%) (g/l) density Example 19.3 <0.1 568 1.14 B Example 19.4 <0.1 490 1.16 C Example 19.9 <0.1 537 1.11 D Example 38 0.8 482 1.08 E Example 21.0 0.2 595 1.11 F Example 20.7 0.2 521 1.15 G Example 19.2 0.1 568 1.12 H

COMPARATIVE EXAMPLE I

[0273] Capsules having the same composition as Example A as described above were prepared according to the process of Example 1 of patent U.S. Pat. No. 6,200,949 comprising drying by spray-drying (atomization) of the emulsion described in Example A.

[0274] The emulsion is dried by spray-drying using a Bowen Lab Model Dryer machine using air with a flow rate of 420 m.sup.3/h at a temperature of 204 C. and an external temperature of 93 C. and a turbine speed of 50 000 rpm.

[0275] Morphological aspect of the particles obtained: polymorphous with aggregates

COMPARATIVE EXAMPLE J

[0276] Capsules having the same composition as Example A as described above were prepared according to the process of Example 1 of patent U.S. Pat. No. 5,508,259 comprising drying by spray-drying (atomization) of the emulsion described in Example A.

[0277] The mixture was dried by spray-drying with a CCM Sulzer machine at an emulsion flow rate of 50 kg/h, air at a flow rate of 320 m.sup.3/h at 350 C. and 0.45 bar.

Morphological Aspect of the Particles Obtained: Polymorphous with Aggregates

TABLE-US-00006 Measured characteristics of the capsules Amount Poured Amount of of free powder encapsulated perfume density Absolute Composition perfume (%) (%) (g/l) density Example I 18.3 2.7 259 1.16 (outside the invention) Example J 11.2 1.7 269 1.12 (outside the invention)

EXAMPLE 1: DEODORANT AND ANTIPERSPIRANT PRODUCT

[0278] An anhydrous antiperspirant aerosol having the following composition was prepared:

TABLE-US-00007 Ingredients (weight %) Dimethicone 23.51 Isopropyl palmitate 4.85 Dimethicone dimethiconol 8.90 Triethyl citrate 5.66 Modified bentonite 2.10 Anhydrous aluminum 28.30 hydroxychloride Perfume capsules of 26.68 Example A Total 100.00

[0279] 35.3 g of dimethicone, 7.3 g of isopropyl palmitate, 13.3 g of dimethicone/dimethiconol and 8.5 g of triethyl citrate are placed in a tank equipped with a stirrer and a bottom turbomixer. The mixture is homogenized with vigorous stirring (1000 rpm). 3.1 g of modified bentonite are then added and the mixture is left to stand for 10 minutes. The mixture is homogenized again with vigorous stirring (1200 rpm), followed by the addition of 42.4 g of anhydrous aluminum hydroxychloride. The mixture is homogenized again with vigorous stirring (1200 rpm), followed by the addition of 40.0 g of capsules of Example A. A thick opaque beige-white liquid was thus obtained, which is introduced into a closed aerosol can. The air is removed from the container, which is then filled with the propellant gas (isobutane) in a 15 (fluid)/85 (gas) ratio.

EXAMPLES C1 AND C2: DEODORANT AND ANTIPERSPIRANT PRODUCTS

[0280] In a manner similar to that of Example 1, anhydrous antiperspirant aerosols having the following compositions were prepared:

TABLE-US-00008 Example C1 Ingredients (weight %) Dimethicone 23.51 Isopropyl palmitate 4.85 Dimethicone dimethiconol 8.90 Triethyl citrate 5.66 Modified bentonite 2.10 Anhydrous aluminum 28.30 hydroxychloride Perfume capsules of 26.68 Example I Total 100.00

TABLE-US-00009 Example C2 Ingredients (weight %) Dimethicone 23.51 Isopropyl palmitate 4.85 Dimethicone dimethiconol 8.90 Triethyl citrate 5.66 Modified bentonite 2.10 Anhydrous aluminum 28.30 hydroxychloride Perfume capsules of 26.68 Example J Total 100.00

Evaluation of the Examples:

[0281] Comparison of the Formulations of Example 1 with the Formulations of Examples C1 and C2 Before Pressurization Under Gas

TABLE-US-00010 Aerosol fluid Appearance Density* Example 1 Thick homogeneous 1.153 beige-white liquid Example C1 Thick non-homogeneous Not beige-white paste measurable Example C2 Thick non-homogeneous Not beige-white paste measurable *the density is measured using a Mettler-Toledo DA-100M densimeter. A sample of the homogenized fluid is taken using a 5 ml syringe and introduced into the densimeter. The machine automatically indicates the density.

COMPARISON OF THE AEROSOLS: EXAMPLE 1, EXAMPLE C1 AND EXAMPLE C2

[0282]

TABLE-US-00011 Sedimentation Appearance Spraying (0.41 Aerosol time of the fluid mm nozzle) Example 1 25 s 0 OK Example C1 15 s 2 Repeated clogging of the nozzle then gas leaks Example C2 13 s 3 OK

[0283] The criteria for evaluating the sedimentation time are the following:

25 s=slow sedimentation
15-24 s=moderate sedimentation
14 s=rapid sedimentation

[0284] The criteria for the appearance of the fluid are the following:

0=no particles visible in the fluid (fluid is completely translucent)
1=small presence of particles visible in the fluid
2=moderate presence of particles visible in the fluid
3=strong presence of particles visible in the fluid
4=very strong presence of particles visible in the fluid
* reference DSPR119 from Precision.

Evaluation Protocol:

[0285] The aerosol is shaken for three seconds to homogenize it. It is then sprayed for 2 seconds onto a scent strip (Granger Veyron reference: 40140 BCSI of size 4 cm14 cm) so as to deposit about 0.07 g of composition. After 1 minute, the olfactory intensity is evaluated (BEF) and is graded from 0 to 10. Perspiration is then stimulated by adding about 0.1 g of water (three sprays) onto the deposited composition. After waiting for 30 seconds, the olfactory intensity is evaluated (AFT). 4 hours later, it is re-evaluated again before and after spraying the same amount of water. 20 hours later, the intensity before/after spraying with water is re-evaluated again in the same manner.

TABLE-US-00012 Odor Odor Odor intensity intensity T0 intensity T4 h T24 h Aerosol BEF AFT BEF AFT BEF AFT Example 1 0 6 6 2.7 6.7 4.0 1.3 4.0 2.7 Example C1 6 8 2 6.7 8.0 1.3 4.7 5.3 0.7 Example C2 6 8 2 4.7 6.3 1.7 3.0 2.3 0.7 BEF = before addition of water; AFT = after addition of water; = olfactory intensity (BEF AFT) Scale of olfactory intensity: 0 to 10 (0 = odorless; 10 = very intense/saturated odor)

[0286] It was thus observed at T0 that the aerosol of Example 1 comprising the perfume capsules according to the invention has no odor before the addition of water, in contrast with the aerosols C1 and C2 (outside the invention), which shows that the perfume capsules in aerosols C1 and C2 are not leaktight even before the addition of water.

[0287] It was also observed, both at 4 hours and at 24 hours, that the aerosol of Example 1 after stimulation with water, gave a more intense odor than that observed for aerosols C1 and C2, which shows greater release of perfume in response to the water stimulus.

EXAMPLE 2: ANTIPERSPIRANT AND DEODORANT PRODUCT

[0288] An anhydrous antiperspirant aerosol having the following composition was prepared:

TABLE-US-00013 Ingredients (weight %) Dimethicone 23.26 Isopropyl palmitate 4.80 Dimethicone dimethiconol 8.80 Triethyl citrate 5.60 Modified bentonite 2.08 Anhydrous aluminum 28.00 hydroxychloride Perfume capsules of 26.40 Example A Free perfume 1.06 Total 100.00

[0289] The perfume capsules of Example A may be replaced with the capsules of Examples B to H described previously.

[0290] 46.5 g of dimethicone, 9.6 g of isopropyl palmitate, 17.6 g of dimethicone/dimethiconol, 11.2 g of triethyl citrate and 2.13 g of perfume are placed in a tank equipped with a stirrer and a bottom turbomixer. The mixture is homogenized with vigorous stirring (1000 rpm). 4.16 g of modified bentonite are then added and the mixture is left to stand for 10 minutes. The mixture is homogenized again with vigorous stirring (1200 rpm), followed by addition of 56.0 g of anhydrous aluminum hydroxychloride. The mixture is homogenized again with vigorous stirring (1200 rpm), followed by addition of 52.8 g of the capsules of Example A. A thick opaque beige-colored liquid was thus obtained, which is introduced into a closed aerosol can. The air is removed from the container, which is then filled with the propellant gas (isobutane) in a 15 (fluid)/85 (gas) ratio.

[0291] About 1.0 g of composition of Example 2 was applied onto the skin. After 1 minute, the perfume odor intensity was evaluated (APPLICATION) and graded from 0 to 10. 2, 4 and 6 hours later, the perfume odor intensity was re-evaluated again (BEF) before adding about 0.1 g of water (three sprays) to the composition applied to the skin. After waiting for 30 seconds, the perfume odor intensity was re-evaluated (AFT).

TABLE-US-00014 Odor Odor Odor intensity Odor intensity T0 intensity T2 h intensity T4 h T6 h Product APPLICATION BEF AFT BEF AFT BEF AFT Example 7.0 3.75 7.5 3.75 3.5 6.5 3.0 2.5 4.5 2.0 2 BEF = before addition of water; AFT = after addition of water = amplitude of difference in intensity of perfume odor (BEF AFT) Scale of perfume odor intensity: 0 to 10 (0 = odorless; 10 = very intense/saturated odor).

[0292] It was thus observed at T0 that the composition of Example 2 has a strong odor which decreases rapidly at T2h, T4h and T6h after application. It was also observed that the spraying of water onto the product at T2h, T4h and T6h leads to an increase in the odor intensity (especially of the fresh notes), which demonstrates substantial release of perfume each time.

EXAMPLE 3: DRY SHAMPOO PRODUCT

[0293] An anhydrous dry shampoo having the following composition was prepared:

TABLE-US-00015 Ingredients (weight %) Calcium carbonate 14.8 Corn starch Dry-Flo 75.0 (Akzo Nobel) Distearylammonium- 2.0 modified hectorite Isopropyl myristate 3.2 Perfume capsules of 5.0 Example F Total 100.00

[0294] The perfume capsules of Example F may be replaced with the capsules of Examples A to E, G and H described previously.

[0295] 14.8 g of calcium carbonate, 75.0 g of corn starch, 2.0 g of modified hectorite and 3.2 g of isopropyl myristate are placed in a tank equipped with a stirrer and a bottom turbomixer. The mixture is turbomixed and stirred for three minutes at 1500 rpm. 5.0 g of capsules of Example F are then added while homogenizing the mixture. The mixture thus obtained is introduced into an aerosol device. The air is removed from the container, which is then filled with the propellant gas (isobutane) in a 15 (fluid)/85 (gas) ratio.

[0296] After spraying the composition onto the hair, it is noted, when the person perspires or on contact with sebum, that perfume is released in the course of the day.

EXAMPLE 4: DRY SHAMPOO PRODUCT

[0297] An anhydrous dry shampoo having the following composition was prepared:

TABLE-US-00016 Ingredients (weight %) Calcium carbonate 14.8 Corn starch Dry-Flo 76.4 (Akzo Nobel) Distearylammonium- 2.0 modified hectorite Isopropyl myristate 3.0 Perfume capsules of 5.0 Example B Free perfume 0.8 Total 100.00

[0298] The perfume capsules of Example B may be replaced with the capsules of Examples A and C to H described previously.

[0299] 14.8 g of calcium carbonate, 76.4 g of corn starch, 2.0 g of modified hectorite, 3.0 g of isopropyl myristate and 0.8 g of free perfume are placed in a tank equipped with a stirrer and a bottom turbomixer. The mixture is turbomixed and stirred for three minutes at 1500 rpm with the paddles and turbomixer. 3.0 g of capsules of Example B are then added while homogenizing the mixture with the paddles. The mixture obtained is introduced into an aerosol device. The air is removed from the container, which is then filled with the propellant gas (isobutane) in a 15 (fluid)/85 (gas) ratio.

[0300] After spraying the composition onto the hair, it is noted, when the person perspires or on contact with sebum, that perfume is released in the course of the day.

EXAMPLE 5: ANTIPERSPIRANT AND DEODORANT PRODUCT

[0301] An anhydrous antiperspirant aerosol having the following composition was prepared:

TABLE-US-00017 Ingredients (weight %) Dimethicone 23.26 Isopropyl palmitate 4.80 Dimethicone dimethiconol 8.80 Triethyl citrate 5.60 Modified bentonite 2.08 Anhydrous aluminum 28.00 hydroxychloride Perfume capsules of 26.40 Example H Free perfume 1.06 Total 100.00

[0302] The perfume capsules of Example H may be replaced with the capsules of Examples A to G described previously.

[0303] 46.5 g of dimethicone, 9.6 g of isopropyl palmitate, 17.6 g of dimethicone/dimethiconol, 11.2 g of triethyl citrate and 2.13 g of perfume are placed in a tank equipped with a stirrer and a bottom turbomixer. The mixture is homogenized with vigorous stirring (1000 rpm). 4.16 g of modified bentonite are then added and the mixture is left to stand for 10 minutes. The mixture is homogenized again with vigorous stirring (1200 rpm), followed by addition of 56.0 g of anhydrous aluminum hydroxychloride. The mixture is homogenized again with vigorous stirring (1200 rpm), followed by addition of 52.8 g of the capsules of Example H. A thick opaque beige-colored liquid was thus obtained, which is then introduced into a closed aerosol can. The air is removed from the container, which is then filled with the propellant gas (isobutane) in a 15 (fluid)/85 (gas) ratio.

[0304] After spraying the composition onto the armpits, it is noted that, on contact with sweat, the perfume of the deposited composition is released and the olfactory effect lasts throughout the day.