Pesticidal mixtures including spiroheterocyclic pyrrolidine diones

Abstract

A pesticidal mixture comprising as active ingredient a mixture of component A and component B, wherein component A is a compound of formula (I) in which Q is i or ii wherein X, Y and Z, m and n, A, G, and R, are as defined as in claim 1, and component B is a compound selected from the insecticides as defined in claim 1. The present invention also relates to methods of using said mixtures for the control of plant pests. ##STR00001##

Claims

1. A pesticidal mixture comprising as active ingredient a mixture of component A and component B, wherein component A is a compound of formula (I) ##STR00018## in which Q is i ##STR00019## m is 1, n is 1, X is methyl, Y is in the ortho position and is methyl, Z is in the para position and is chloro, G is (CO)OCH.sub.2CH.sub.3, A is methyl and R is methyl; or an agrochemically acceptable salt or an N-oxide thereof; and component B is flonicamid; wherein the weight ratio of component A to component B is from 33:1 to 1:5.

2. A pesticidal mixture according to claim 1, wherein the mixture comprises an agricultural acceptable carrier and optionally a surfactant.

3. A pesticidal mixture according to claim 1, wherein the mixture comprises formulation adjuvants.

4. A pesticidal mixture according to claim 1, wherein the weight ratio of component A to component B is from 17:1 to 1:5.

5. A method of controlling insects or acarines, which comprises applying to insects or acarines, to a locus of insects or acarines, or to a plant susceptible to attack by insects or acarines a combination of components A and B, wherein the combination of components A and B is a mixture as defined in claim 1, the mixture further comprising an agricultural acceptable carrier and optionally a surfactant.

6. The method according to claim 5 for controlling insects, wherein the insects are neonicotinoid resistant.

7. A seed comprising a mixture as defined in claim 1.

Description

EXAMPLES

(1) A synergistic effect exists whenever the action of an active ingredient combination is greater than the sum of the actions of the individual components.

(2) The action to be expected E for a given active ingredient combination obeys the so-called COLBY formula and can be calculated as follows (COLBY, S. R. Calculating synergistic and antagonistic responses of herbicide combination. Weeds, Vol. 15, pages 20-22; 1967):

(3) ppm=milligrams of active ingredient (=a.i.) per liter of spray mixture

(4) X=% action by active ingredient A) using p ppm of active ingredient

(5) Y=% action by active ingredient B) using q ppm of active ingredient.

(6) According to COLBY, the expected (additive) action of active ingredients A)+B) using p+q ppm of active ingredient is

(7) $E=X+Y-\frac{X.Math.Y}{100}$

(8) If the action actually observed (0) is greater than the expected action (E), then the action of the combination is super-additive, i.e. there is a synergistic effect. In mathematical terms the synergism factor SF corresponds to O/E. In the agricultural practice an SF of 1.2 indicates significant improvement over the purely complementary addition of activities (expected activity), while an SF of 0.9 in the practical application routine signals a loss of activity compared to the expected activity.

(9) Table 45 shows mixtures of T1.055, T1 ii.055 and T1 iii.055 and a Component B of the present invention to be used for demonstrating control on a wide range of pests. As the percent of mortality cannot exceed 100 percent, the unexpected increase in insecticidal activity can be greatest only when the separate active ingredient components alone are at application rates providing considerably less than 100 percent control. Synergy may not be evident at low application rates where the individual active ingredient components alone have little activity. However, in some instances high activity can be observed for combinations wherein individual active ingredient alone at the same application rate have essentially no activity.

(10) Myzus persicae (Green Peach Aphid):

(11) Feeding/Residual Contact Activity, Preventive

(12) Sunflower leaf discs were placed on agar in a 24-well microtiter plate and sprayed with the DMSO test solutions of Mixtures (as provided by Table 45). After drying, the leaf discs were infested with an aphid population of mixed ages. After an incubation period of 6 DAT (days after treatment), samples were checked for mortality. (1 PPM=1 mg l.sup.1) Results are shown in Table 46 and 47.

(13) TABLE-US-00005 TABLE 46 AVERAGE EXPECT- DEAD IN % ED PPM Al AFTER 6 DAYS MORTAL- OBSERVED T1.055 Flonicamid T1.055 Flonicamid ITY MORTALITY 50 0.75 10 0 10 10 50 1.5 10 0 10 0 50 3 10 7.5 16.75 25* 50 6 10 40 46 55* 50 12 10 82.5 84.25 95*

(14) TABLE-US-00006 TABLE 47 AVERAGE EXPECT- DEAD IN % ED PPM Al AFTER 6 DAYS MORTAL- OBSERVED T1iii.055 Flonicamid T1iii.055 Flonicamid ITY MORTALITY 50 0.75 40 0 40 85* 50 1.5 40 0 40 80* 50 3 40 7.5 44.5 90* 50 6 40 40 64 90* 50 12 40 82.5 89.5 95*
Tetranychus urticae (Two-Spotted Spider Mite):
Feeding/Contact Activity, Preventive

(15) Bean leaf discs on agar in 24-well microtiter plates were sprayed with the DMSO test solutions of certain Mixtures (as provided by Table 45). After drying, the leaf discs were infested with mite populations of mixed ages. 8 days later, discs were checked for mortality against mobile stages. (1 PPM=1 mg l.sup.1) Results are shown in Table 48 and 49.

(16) TABLE-US-00007 TABLE 48 AVERAGE EXPECT- DEAD IN % ED PPM Al AFTER 8 DAYS MORTAL- OBSERVED T1.055 Flonicamid T1.055 Flonicamid ITY MORTALITY 200 50 40 0 40 25 200 100 40 0 40 65* 200 200 40 0 40 75* 200 400 40 0 40 80* 200 800 40 12.5 47.5 80*

(17) TABLE-US-00008 TABLE 49 AVERAGE EXPECT- DEAD IN % ED PPM Al AFTER 8 DAYS MORTAL- OBSERVED T1iii.055 Flonicamid T1iii.055 Flonicamid ITY MORTALITY 50 200 80 0 80 70 25 200 70 0 70 85* 12.5 200 40 0 40 75* 6.25 200 0 0 0 50* 3.125 200 0 0 0 0