Metal amides of cyclic amines

Abstract

Compounds, and oligomers of the compounds, are synthesized with cyclic amine ligands attached to a metal atom. These compounds are useful for the synthesis of materials containing metals. Examples include pure metals, metal alloys, metal oxides, metal nitrides, metal phosphides, metal sulfides, metal selenides, metal tellurides, metal borides, metal carbides, metal silicides and metal germanides. Techniques for materials synthesis include vapor deposition (chemical vapor deposition and atomic layer deposition), liquid solution methods (sol-gel and precipitation) and solid-state pyrolysis. Suitable applications include electrical interconnects in microelectronics and magnetoresistant layers in magnetic information storage devices. The films have very uniform thickness and high step coverage in narrow holes.

Claims

1. A composition comprising a compound represented by the formula M.sub.xA.sub.y or an oligomer thereof; and wherein M is a metal; A is a cyclic amine ligand bonded to said M; and x and y are positive integers; wherein said metal M is selected from the group consisting of manganese, iron, cobalt, nickel, zinc, chromium, vanadium, titanium, magnesium, calcium, strontium, barium, tellurium, cadmium, tin, lead, palladium, platinum, rhodium, ruthenium, osmium, iridium, molybdenum, tungsten, niobium, tantalum, aluminum, gallium, scandium, antimony, indium, lutetium, ytterbium, thulium, erbium, thallium, yttrium, holmium, dysprosium, terbium, gadolinium, europium, samarium, neodymium, praseodymium, cerium, bismuth, and uranium.

2. The composition of claim 1, wherein the compound has the structure ##STR00030## or oligomers thereof, where the R.sup.1 through R.sup.16 are chosen independently from hydrogen, alkyl, substituted alkyl, cycloalkyl, substituted cycloalkyl, aryl, substituted aryl, alkenyl, substituted alkenyl, alkynyl, substituted alkynyl, trialkylsilyl, dialkylamide or haloalkyl groups.

3. The composition of claim 2, wherein the metal is selected from manganese, iron, cobalt, nickel, chromium, vanadium, titanium, magnesium, calcium, strontium, barium, cadmium, zinc, tin, lead, tellurium, europium, palladium, platinum, rhodium, ruthenium, osmium, iridium, molybdenum, tungsten, niobium and tantalum.

4. The composition of claim 1, wherein the cyclic amine ligand comprises 2,2,5,5-tetramethylpyrrolidine.

5. The composition of claim 3, wherein the compound is bis(2,2,5,5-tetramethylpyrrolidin-1-yl)metal(II) represented by the general formula ##STR00031## or oligomers thereof, wherein the metal M is selected from the group consisting of manganese, iron, cobalt, nickel, chromium, vanadium, titanium, magnesium, calcium, strontium, barium, cadmium, zinc, tin, lead, tellurium, europium, palladium, platinum, rhodium, ruthenium, osmium, iridium, molybdenum, tungsten, niobium and tantalum.

6. The composition of claim 4, wherein the compound has the chemical name bis(2,2,5,5-tetramethylpyrrolidin-1-yl)manganese(II) dimer and represented by the formula ##STR00032##

7. The composition of claim 1, wherein the compound has the chemical name bis(2,2,5,5-tetramethylpyrrolidin-1-yl)iron(II) and formula: ##STR00033##

8. The composition of claim 1, wherein the compound has the chemical name bis(2,2,5,5-tetramethylpyrrolidin-1-yl)cobalt(II) and formula ##STR00034##

9. The composition of claim 1, wherein the compound has the chemical name bis(2,2,5,5-tetramethylpyrrolidin-1-yl)nickel(II) and formula ##STR00035##

10. The composition of claim 1, wherein the compound has the chemical name bis(2,2,5,5-tetramethylpyrrolidin-1-yl)titanium(II) dimer and formula ##STR00036##

11. The composition of claim 1, wherein the compound has the chemical name bis(2,2,5,5-tetramethylpyrrolidin-1-yl)chromium(II) dimer and formula ##STR00037##

12. The composition of claim 1, wherein the compound is represented by the general formula, ##STR00038## or oligomers thereof where the R.sup.1 through R.sup.20 are chosen independently from hydrogen, alkyl, substituted alkyl, cycloalkyl, substituted cycloalkyl, aryl, substituted aryl, alkenyl, substituted alkenyl, alkynyl, substituted alkynyl, trialkylsilyl, dialkylamide or haloalkyl groups.

13. The composition of claim 12, wherein the metal M is selected from the group consisting of manganese, iron, cobalt, nickel, chromium, vanadium, titanium, calcium, strontium, barium, lead, tellurium, europium, palladium, platinum, rhodium, ruthenium, osmium, iridium, molybdenum, tungsten, niobium and tantalum.

14. The composition of claim 12, wherein the cyclic amine ligand comprises 2,2,6,6-tetramethylpiperidine.

15. The composition of claim 13 wherein the compound is bis(2,2,6,6-tetramethylpiperidin-1-yl)metal(II) represented by the general formula ##STR00039##

16. The composition of claim 14, wherein the compound has the chemical name bis(2,2,6,6-tetramethylpiperidin-1-yl)manganese(II) and formula ##STR00040##

17. The composition of claim 14, wherein the compound has the chemical name bis(2,2,6,6-tetramethylpiperidin-1-yl)cobalt(II) and formula: ##STR00041##

18. The composition of claim 14, wherein the compound has the chemical name bis(2,2,6,6-tetramethylpiperidin-1-yl)nickel(II) and formula: ##STR00042##

19. The composition of claim 14, wherein the compound has the chemical name bis(2,2,6,6-tetramethylpiperidin-1-yl)titanium(II) and formula: ##STR00043##

20. The composition of claim 1, wherein the compound is represented by the general formula, ##STR00044## or oligomers thereof where the R.sup.1 through R.sup.24 are chosen independently from hydrogen, alkyl, substituted alkyl, cycloalkyl, substituted cycloalkyl, aryl, substituted aryl, alkenyl, substituted alkenyl, alkynyl, substituted alkynyl, trialkylsilyl, dialkylamide or haloalkyl groups.

21. The composition of claim 20, wherein the metal M is selected from the group consisting of aluminum, cobalt, iron, gallium, vanadium, titanium, rhodium, ruthenium, osmium, iridium, chromium, molybdenum, tungsten, niobium, tantalum, scandium, antimony, indium, lutetium, ytterbium, thulium, erbium, thallium, yttrium, holmium, dysprosium, terbium, gadolinium, europium, samarium, neodymium, praseodymium, cerium, bismuth and uranium.

22. The composition of claim 1, wherein the compound is represented by the general formula, ##STR00045## or oligomers thereof where the R.sup.1 through R.sup.30 are chosen independently from hydrogen, alkyl, substituted alkyl, cycloalkyl, substituted cycloalkyl, aryl, substituted aryl, alkenyl, substituted alkenyl, alkynyl, substituted alkynyl, trialkylsilyl, dialkylamide or haloalkyl groups.

23. The composition of claim 22, wherein the metal M is selected from the group consisting of aluminum, cobalt, iron, gallium, vanadium, titanium, rhodium, ruthenium, osmium, iridium, chromium, molybdenum, tungsten, niobium, tantalum, scandium, antimony, indium, lutetium, ytterbium, thulium, erbium, thallium, yttrium, holmium, dysprosium, terbium, gadolinium, europium, samarium, neodymium, praseodymium, cerium, bismuth or uranium.

24. A method comprising: depositing material from a compound represented by the formula M.sub.xA.sub.y or an oligomer thereof; and wherein M is a metal; A is a cyclic amine ligand bonded to said metal M; and x and y are positive integers; wherein said metal M is selected from the group consisting of manganese, iron, cobalt, nickel, zinc, chromium, vanadium, titanium, magnesium, calcium, strontium, barium, tellurium, cadmium, tin, lead, palladium, platinum, rhodium, ruthenium, osmium, iridium, molybdenum, tungsten, niobium, tantalum, aluminum, gallium, scandium, antimony, indium, lutetium, ytterbium, thulium, erbium, thallium, yttrium, holmium, dysprosium, terbium, gadolinium, europium, samarium, neodymium, praseodymium, cerium, bismuth, and uranium.

25. The method of claim 24, wherein said depositing includes a second reactant.

26. The method of claim 25, wherein said depositing second reactant is carried out at the same time as said depositing a compound.

27. The method of claim 25, wherein said depositing second reactant and said depositing a compound are carried out at separate times.

28. The method of claim 27, further comprising applying a purge gas between said depositing a compound and said depositing a second reactant.

29. The method of claim 25, wherein said second reactant comprises hydrogen.

30. The method of claim 25, wherein said second reactant comprises ammonia.

31. The method of claim 25, wherein said second reactant comprises water, oxygen, hydrogen peroxide, nitrogen dioxide or ozone.

32. The method of claim 25, wherein said second reactant comprises hydrogen sulfide.

33. The method of claim 25, wherein said second reactant comprises diborane.

34. The method of claim 24, wherein said compound is deposited from a solvent.

35. The method of claim 34, wherein said solvent is a hydrocarbon selected from a group consisting of alkanes, alkenes, terpenes, and combinations thereof.

36. The method of claim 34, wherein said solvent is a saturated hydrocarbon selected from the group consisting dodecane, tetradecane, 2,6,10-trimethyldodecane, 2,2,4,4,6,8,8-heptamethylnonane, 2,6,10-trimethylpentadecane and 2,6,10,14-tetramethylpentadecane and combinations thereof.

37. The method of claim 34, wherein said solvent is a trialkylamine.

38. The method of claim 37, wherein said trialkylamine is selected from the group consisting of tri-n-butylamine, tri-n-pentylamine, tri-n-hexylamine, tri-n-heptylamine, tri-n-octylamine and combinations thereof.

Description

BRIEF DESCRIPTION OF THE DRAWINGS

(1) The foregoing and various other aspects, features, and advantages of the present invention, as well as the invention itself, may be more fully appreciated with reference to the following detailed description of the invention when considered in connection with the following drawings. The drawings are presented for the purpose of illustration only and are not intended to be limiting of the invention, in which:

(2) The FIGURE is a diagram of the structure of bis(2,2,5,5-tetramethylpyrrolidino)manganese(II) dimer molecules in their crystal, as determined by the methods of X-ray crystallography.

DETAILED DESCRIPTION OF THE INVENTION

(3) Metal cyclic amides, as used herein, are compounds that include a metal or metals attached to anionic ligands derived from cyclic amines. A cyclic amine, as used herein, means a heterocyclic compound whose ring structure includes one nitrogen atom while the other ring atoms (typically 4 or 5) are carbon.

(4) In one or more embodiments, the metal cyclic amine has the general formula MA.sub.x where x is selected to provide compound neutrality. Typically, x is 2 or 3. MA.sub.x is preferably a monomer, but may be an oligomer, in which case the compound may be reported as [MA.sub.x].sub.y, where y is the degree of oligiomerization and typically ranges up to 3 (trimer), more preferably 2 (dimer), and most preferably 1 (monomer). Additional neutral ligands L may also be present, corresponding to a formula (MA.sub.xL.sub.n).sub.y, where n is a positive number.

(5) In one or more embodiments, M is a main group element, transition metal or rare earth metal in an oxidation state typically 2 or 3. Exemplary metals include manganese, iron, cobalt, nickel, zinc, chromium, vanadium, titanium, magnesium, calcium, strontium, barium, tellurium, cadmium, tin, lead, palladium, platinum, rhodium, ruthenium, osmium, iridium, molybdenum, tungsten, niobium, tantalum, aluminum, gallium, scandium, antimony, indium, lutetium, ytterbium, thulium, erbium, thallium, yttrium, holmium, dysprosium, terbium, gadolinium, europium, samarium, neodymium, praseodymium, cerium, bismuth, and uranium.

(6) In one embodiment, cyclic amines have five-member pyrrolidinate rings and are represented by the following structure or oligomers thereof when forming compounds with metals M in the oxidation state +2:

(7) ##STR00006##

(8) In this formula, R.sup.1 through R.sup.16, or R.sup.n where n=1-16, represent groups made from one or more non-metal atoms. In some embodiments, R.sup.n may be chosen independently from hydrogen, alkyl, substituted alkyl, cycloalkyl, substituted cycloalkyl, aryl, substituted aryl, alkenyl, substituted alkenyl, alkynyl, substituted alkynyl, trialkylsilyl, dialkylamide or haloalkyl groups, wherein the haloalkyl groups include fluoroalkyls, chloroalkyls and bromoalkyls. In some embodiments, the groups attached to carbons adjacent to nitrogen (that is, R.sup.1, R.sup.2, R.sup.7, R.sup.8, R.sup.9, R.sup.10, R.sup.15 and R.sup.16) are not hydrogen, so that the steric bulk of the cyclic amine ligands provides monomeric compounds, which are more volatile than oligomeric compounds. In certain embodiments, the cyclic amine ligands are 2,2,5,5-tetramethylpyrrolidinates forming compounds with metals M in the oxidation state +2:

(9) ##STR00007##

(10) In one or more embodiments, the cyclic amine ligands are substituted piperidinates, forming compounds with metals M in the oxidation state +2 represented by the following structure or oligomers thereof:

(11) ##STR00008##

(12) In this formula, R.sup.1 through R.sup.20, or R.sup.n where n=1-20, represent groups made from one or more non-metal atoms. In some embodiments, R.sup.n may be chosen independently from hydrogen, alkyl, substituted alkyl, cycloalkyl, substituted cycloalkyl, aryl, substituted aryl, alkenyl, substituted alkenyl, alkynyl, substituted alkynyl, trialkylsilyl, dialkylamide or haloalkyl groups, wherein the haloalkyl groups include fluoroalkyls, chloroalkyls and bromoalkyls. In preferred embodiments, the groups attached to carbons adjacent to nitrogen (that is, R.sup.1, R.sup.2, R.sup.9, R.sup.10, R.sup.11, R.sup.12, R.sup.19 and R.sup.20) are not hydrogen, so that the steric bulk of the ligands provides monomeric compounds, which are more volatile than oligomeric compounds.

(13) In some embodiments, the cyclic amine ligands are 2,2,6,6-tetramethylpiperidinates forming compounds with metals M in the oxidation state +2:

(14) ##STR00009##

(15) Some suitable metals in the +2 oxidation state include Mn(II), Fe(II), Co(II), Ni(II), Zn(II), Cr(II), V(II), Ti(II), Cu(II), Ca(II), Sr(II), Ba(II), Te(II), Pb(II), Pd(II), Pt(II), Rh(II), Ru(II) or Os(II).

(16) In certain embodiments, the cyclic amines are tris(pyrrolidinate) forming compounds with M in the oxidation state +3 represented by the following structure or oligomers thereof

(17) ##STR00010##

(18) In formula 5, R.sup.n, where n is any integer between 1 and 24, represent groups chosen independently from hydrogen, alkyl, substituted alkyl, cycloalkyl, substituted cycloalkyl, aryl, substituted aryl, alkenyl, substituted alkenyl, alkynyl, substituted alkynyl, trialkylsilyl, dialkylamide or haloalkyl groups, wherein the haloalkyl groups include fluoroalkyls, chloroalkyls and bromoalkyls.

(19) Some suitable metals in the +3+ oxidation state in formula 5 include aluminum, cobalt, iron, gallium, vanadium, titanium, rhodium, ruthenium, osmium, iridium, chromium, molybdenum, tungsten, niobium, tantalum, scandium, antimony, indium, lutetium, ytterbium, thulium, erbium, thallium, yttrium, holmium, dysprosium, terbium, gadolinium, europium, samarium, neodymium, praseodymium, cerium, bismuth or uranium.

(20) In certain embodiments, the cyclic amines are tris(piperidinate) forming compounds with M in the oxidation state +3 represented by the following structure or oligomers thereof:

(21) ##STR00011##

(22) In formula 6, R.sup.n, where n is any integer between 1 and 30, represent groups chosen independently from hydrogen, alkyl, substituted alkyl, cycloalkyl, substituted cycloalkyl, aryl, substituted aryl, alkenyl, substituted alkenyl, alkynyl, substituted alkynyl, trialkylsilyl, dialkylamide or haloalkyl groups, wherein the haloalkyl groups include fluoroalkyls, chloroalkyls and bromoalkyls.

(23) Some suitable metals in the +3+ oxidation state in formula 6 include aluminum, cobalt, iron, gallium, vanadium, titanium, rhodium, ruthenium, osmium, iridium, chromium, molybdenum, tungsten, niobium, tantalum, scandium, antimony, indium, lutetium, ytterbium, thulium, erbium, thallium, yttrium, holmium, dysprosium, terbium, gadolinium, europium, samarium, neodymium, praseodymium, cerium, bismuth or uranium.

(24) Synthetic Scheme

(25) In certain embodiments, cyclic amines and their compounds with metals described herein can be synthesized according to the reactions described in the examples. Adding different substituents to the cyclic amines can be accomplished by the selection of different organic starting materials as is understood by one of skill in the art.

(26) Vapor Deposition

(27) In a vapor deposition process, the metal cyclic amine vapor and, optionally, a vapor of a second reactant are supplied to a surface. When the vapors are supplied at the same time to a surface, or if the optional second reactant is omitted, the process is called chemical vapor deposition (CVD). When the vapors are supplied alternately to a surface, then the process is called atomic layer deposition (ALD). Typical second reactants include hydrogen gas, ammonia gas, water, oxygen, hydrogen peroxide, nitrogen dioxide, ozone, hydrogen sulfide, diborane. When hydrogen gas or another reducing gas is chosen as the second reactant, a metal may be deposited. When ammonia gas or another reactive source of nitrogen is chosen as the second reactant, a metal nitride is deposited. When water vapor, oxygen or ozone or another reactive source of oxygen is chosen as the second reactant, a metal oxide is deposited. When hydrogen sulfide or another reactive source of sulfur is chosen as the second reactant, a metal sulfide is deposited. When diborane or another reactive source of boron is chosen as the second reactant, a metal boride is deposited.

(28) According to one or more embodiments, a metal cyclic amide is introduced onto a substrate as a vapor. Vapors of precursors may be formed by conventional methods from either liquid or solid precursors. In one or more embodiments, a liquid precursor or a liquid solution of it may be vaporized by flowing it along a tube heated, for example to about 100 to 200 C. A carrier gas may also be flowed through the heated tube to assist in the transport of the vapor into the deposition region. The liquid may also be vaporized by nebulization into a carrier gas preheated above the vaporization temperature. The nebulization may be carried out pneumatically, ultrasonically, or by other suitable methods. Solid precursors to be nebulized may be dissolved in organic solvents, including hydrocarbons such as decane, dodecane, tetradecane, toluene, xylene and mesitylene, ethers, esters, ketones, amines and chlorinated hydrocarbons. Solutions of liquid precursors may have lower viscosities than pure liquid precursors, so that in some cases it may be preferable to nebulize and evaporate solutions rather than pure liquids. The precursor liquid or precursor solutions may also be evaporated with thin-film evaporators, by direct injection of the liquids or solutions into a heated zone, or by heating in a bubbler. Commercial equipment for vaporization of liquids is made by Brooks Instruments (Hatfield, Pa.), MKS Instruments (Andover, Mass.), ATMI, Inc. (Danbury, Conn.) and COVA Technologies (Colorado Springs, Colo.). Ultrasonic nebulizers are made by Sonotek Corporation (Milton, N.Y.) and Cetac Technologies (Omaha, Nebr.).

(29) The metal precursors described herein may be reacted with a reducing agent, e.g., hydrogen gas, to form films of the metal. For example, a nickel(II) cyclic amine may be reacted with hydrogen gas to form nickel metal. In other embodiments, the metal precursors of the present invention may also be reacted with other suitably reactive reducing compounds to form metals. In some embodiments, the metal precursors described herein may be reacted with ammonia gas to form metal nitrides. For example, a cobalt(II) cyclic amine may be reacted with ammonia gas to form cobalt nitride. In other embodiments, the metal precursors described herein may be reacted with water vapor to form metal oxides. For example, a nickel(II) cyclic amine may be reacted with water vapor to form nickel oxide.

(30) Deposition of the precursors described herein may be carried out using atomic layer deposition (ALD). ALD introduces a metered amount of a first reactant into a deposition chamber having a substrate therein for layer deposition. A thin layer of the first reactant is deposited on the substrate. Then any unreacted first reactant and volatile reaction by-products are removed by a vacuum pump and, optionally, a flow of inert carrier gas. A metered amount of a second reactant component is then introduced into the deposition chamber. The second reactant deposits on and reacts with the already deposited layer from the first reactant. Alternating doses of first and second reactants are introduced into the deposition chamber and deposited on the substrate to form a layer of controlled composition and thickness. The time between doses may be on the order of seconds and is selected to provide adequate time for the just-introduced component to react with the surface of the film and for any excess vapor and byproducts to be removed from the headspace above the substrate. It has been determined that the surface reactions are self-limiting so that a reproducible layer of predictable composition is deposited. As will be appreciated by one of ordinary skill in the art, deposition processes utilizing more than two reactant components are within the scope of the invention.

(31) In other embodiments, deposition of the precursors described herein may be carried out by CVD.

EXAMPLES

(32) The following examples are provided for the purpose of illustration only and should not be construed as limiting the invention in any manner.

(33) All reactions and manipulations described in these methods can be conducted under a pure nitrogen atmosphere using either an inert atmosphere box or standard Schlenk techniques. The compounds produced by these procedures generally react with moisture and/or oxygen in the ambient air, and hence, can be stored and handled under an inert, dry atmosphere such as pure nitrogen or argon gas.

Example 1. Synthesis of 2,2,5,5-tetramethylpyrrolidine by ring contraction

(34) The following sequence of reactions can also be used to prepare 2,2,5,5-tetramethylpyrrolidine:

(35) ##STR00012##

(36) These steps are described in more detail as follows:

(37) Condensation of acetone with ammonia to form 2,2,6,6-tetramethylpiperidin-4-one:

(38) ##STR00013##

(39) This intermediate, 2,2,6,6-tetramethylpiperidin-4-one, can also be purchased commercially.

(40) Bromination of 2,2,6,6-tetramethylpiperidin-4-one:

(41) ##STR00014##

(42) 2,2,6,6-Tetramethylpiperidin-4-one (100 g, 0.644 mol) was dissolved in glacial acetic acid (HOAc) (395 mL) under water bath cooling. A solution of Br.sub.2 (205.8 g, 1.288 mol) in HOAc (285 mL) was added dropwise over the course of 6 hours. After 1 day, the reaction mixture was filtered. The isolated solid was washed with HOAc (200 mL), H.sub.2O (200 mL) and finally with Et.sub.2O (2200 mL). After air-drying for 7-10 days the product was obtained as a light beige powder (229.55 g, 90%). mp 201 C. (dec.). .sup.1H NMR (CDCl.sub.3/MeOH-d.sub.4, 2:1 v/v): 1.45 (s, 6H, 2 CH.sub.3), 1.88 (s, 6H, 2 CH.sub.3), 5.63 (s, 2H, 2 CHBr). See S. W. Stork and M. W. Makinen, Facile Synthesis of 3-Formyl-2,2,5,5-tetramethyl-1-oxypyrroline, Synthesis 1309 (1999).

(43) Ring contraction by Favorskii rearrangement in ammonia:

(44) ##STR00015##

(45) 3,5-Dibromo-2,2,6,6-tetramethylpiperidin-4-one (75 g, 0.19 mol) was added in small portions to 750 mL of concentrated aqueous ammonia with magnetic stirring. After several minutes the salt dissolved. The solution was saturated with sodium hydroxide added in the form of tablets. A light, needle-shaped precipitate formed. After filtration and drying, 25 g (78%) of a white solid was obtained with sufficient purity to be used in the next step. See C. Sandris and G. Ourisson, Bull. Soc. Chim. France 345 (1958); H. Pauly, Ann. Chem. 322, 77 (1902).

(46) Hofmann degradation of the carboxamide to the pyrrolidone:

(47) ##STR00016##

(48) A solution of sodium hypobromite was prepared by dissolving 43 g of sodium hydroxide in 150 mL of distilled water, cooling to 0 C. in an ice bath, and slowly adding 35 g of bromine while stirring vigorously. After about 10 minutes, a solution of 30 g of 3-aminocarbonyl-2,2,6,6-tetramethyl-3-pyrroline in 250 mL of distilled water was added gradually to the cooled and stirred solution of sodium hypobromite. The initially colorless or slightly yellowish reaction mixture was gradually heated to reflux on a water bath. Its color became greenish, then yellow, orange and finally dark red after about an hour. As soon as it turned dark red, the solution was cooled to room temperature. 150 g of sodium hydroxide pellets were added with stirring. As soon as the pellets dissolved, the mixture was immediately steam-distilled into a receiving flask cooled in ice, until about 150 mL of distillate was obtained. This distillate was saturated with sodium hydroxide and sodium chloride, and then extracted with ether. After low-pressure distillation (80 C./40 Torr), 13.2 g (55%) of a colorless liquid was obtained. (b.p. 169 C./747 Torr). See C. Salvi, C. Fabre, A. Rassat, R. Chiarelli, European Patent Application 423 033 (1990); R. M. Dupeyre, A. Rassat and P. Rey, Bull. Soc. Chim. France 3643 (1965); C. Sandris and G. Ourisson, Bull. Soc. Chim. France 345 (1958); H. Pauly, Ann. Chem. 322, 77 (1902).

(49) Wolff-Kishner reduction of the ketone using hydrazine:

(50) ##STR00017##

(51) A mixture of 2,2,5,5-tetramethyl-3-oxopyrrolidine (1.97 g, 0.014 mol), hydrazine hydrate (2.1 ml, 0.042 mol), potassium hydroxide (2.8 g, 0.050 mol) and diethylene glycol monoethyl ether (10 mL) was heated at 135 C. until the evolution of nitrogen ceased (14 hr). The reflux condenser was then replaced with a distillation condenser and the bath temperature gradually increased to 195 C. The distillate was saturated with anhydrous potassium carbonate, and the organic layer separated and distilled at atmospheric pressure, collecting a fraction boiling at 105-125 C. This material was redistilled to give 1.3 g (73%) of pure 2,2,5,5-tetramethylpyrrolidine, b. p. 110-115 C. See W. R. Couet, R. C. Brasch, G. Sosnovsky, J. Lukszo, I. Prakash, C. T. Gnewuch and T. N. Tozer, Influence of the chemical structure of nitroxyl spin labels on their reduction by ascorbic acid, Tetrahedron 41, 1165-1172 (1985).

Example 2. Synthesis of 2,2,5,5-tetramethylpyrrolidine from nitro ketones

(52) The following reactions can be used to synthesize 2,2,5,5-tetramethylpyrrolidine from but-3-en-2-one and 2-nitropropane:

(53) ##STR00018##
See E. Lunt, Nitro Compounds, Proc. Int. Symposium, Tetrahedron Suppl., 291 (1963).

Example 3. Synthesis of 2,2,5,5-tetramethylpyrrolidine by catalytic cyclization

(54) 2,5-dimethyl-1,5-hexadiene is heated in the presence of a solid catalyst, such as a zeolite.

(55) ##STR00019##

(56) This synthesis could be scaled up industrially to run as a continuous process, but the yield and purity of the product are low. See Michael Hess, Wolfgang Hoelderich and Matthias Schwartzmann, Preparation of N-Heterocycles. U.S. Pat. No. 4,929,733(1990).

Example 4. Preparation of bis(2,2,5,5-tetramethylpyrrolidinato)manganese(II) dimer

(57) ##STR00020##

(58) 2,2,5,5-tetramethylpyrrolidine made according to Examples 1, 2 or 3 was reacted with n-butyl lithium in ether to produce lithium 2,2,5,5-tetramethylpyrrolidinate. The ether was evaporated under low pressure. MnBr.sub.2(THF).sub.2 and pentane were added to the lithium 2,2,5,5-tetramethylpyrrolidinate. The reaction mixture was allowed to stir at room temperature until reaction was complete (typically overnight), and then was filtered to remove solid lithium bromide byproduct. The volatile solvents (pentane and tetrahydrofuran) were removed from the filtered liquid under vacuum, the flask being kept at room temperature by immersion in a water bath. The resulting crude bis(2,2,5,5-tetramethylpyrrolidinato)manganese(II) was then purified by vacuum sublimation at temperatures up to 80 C and collected on a water-cooled cold finger as a yellow solid. A study of the solid by X-ray crystallography showed that it is a dimer in the solid, as shown in the FIGURE and drawn in the formula above this paragraph.

Example 5. Preparation of bis(2,2,5,5-tetramethylpyrrolidinato)iron(II)

(59) ##STR00021##

(60) Example 4 is repeated with FeBr.sub.2(DME) in place of MnBr.sub.2(THF).sub.2.

Example 6. Preparation of bis(2,2,5,5-tetramethylpyrrolidinato)cobalt(II)

(61) ##STR00022##

(62) Example 4 is repeated with CoBr.sub.2(DME) in place of MnBr.sub.2(THF).sub.2.

Example 7. Preparation of bis(2,2,5,5-tetramethylpyrrolidinato)nickel(II)

(63) ##STR00023##

(64) Example 4 is repeated with NiBr.sub.2(DME) in place of MnBr.sub.2(THF).sub.2.

Example 8. Preparation of bis(2,2,6,6-tetramethylpiperidinato)manganese(II)

(65) ##STR00024##

(66) Commercially available 2,2,6,6-tetramethylpiperidine was reacted with n-butyl lithium in ether to form lithium 2,2,6,6-tetramethylpiperidinate. The ether was evaporated under vacuum. MnBr.sub.2(THF).sub.2 and pentane were added to the lithium 2,2,6,6-tetramethylpiperidinate. The reaction mixture was allowed to stir at room temperature until reaction was complete (usually overnight), and then filtered to remove solid lithium bromide. The volatile solvents (pentane and tetrahydrofuran) were removed under vacuum, the flask being kept at room temperature by immersion in a water bath. The resulting crude bis(2,2,6,6-tetramethylpiperidinato)manganese(II) was purified by sublimation at a temperature up to 80 C and collected on a water-cooled cold finger as a yellow solid. X-ray analysis of the solid showed unit cell parameters a=11.17, b=15.08, c=16.28, =97.87, =96.86, =105.61. These parameters have not been reported previously, showing that this is a new compound. However, the quality of the crystal was not sufficient to determine its molecular structure. Proton NMR has 3 or 4 broad resonances, showing that the compound is paramagnetic.

Example 9. Preparation of bis(2,2,6,6-tetramethylpiperidinato)iron(II)

(67) ##STR00025##

(68) Example 8 is repeated with FeI.sub.2 in place of MnBr.sub.2(THF).sub.2.

Example 10. Preparation of bis(2,2,6,6-tetramethylpiperidinato)cobalt(II)

(69) ##STR00026##

(70) Example 8 is repeated with CoBr.sub.2(DME) in place of MnBr.sub.2(THF).sub.2.

Example 11. Preparation of bis(2,2,6,6-tetramethylpiperidinato)nickel(II)

(71) ##STR00027##

(72) Example 8 is repeated with NiBr.sub.2(DME) in place of MnBr.sub.2(THF).sub.2.

Example 12. Alternative preparation of bis(2,2,6,6-tetramethylpiperidinato)manganese(II), Mn(TMPP)2

(73) ##STR00028##

12a. Synthesis of n-butylsodium, nBuNa

(74) The compound nBuNa was prepared following a literature procedure from Organometallics 1988, 7, 277. NaO.sup.tBu was made fresh from HO.sup.tBu and Na.sup.0. Freshly prepared Na.sup.0 foil was added to 2-4 fold excess HO.sup.tBu and stirred at reflux for 24 hours. The remaining HO.sup.tBu was removed in vacuum resulting in white solid NaO.sup.tBu that was immediately used in the synthesis of nBuNa.

12b. Synthesis of (2,2,6,6-tetramethylpiperidinato)sodium trimer, Na3(TMPP)3

(75) The compound Na.sub.3TMPP.sub.3 was prepared following a literature procedure from J. Organomet. Chem. 1999, 587, 88. In some cases, adding excess nBuNa was necessary to ensure complete formation of Na.sub.3TMPP.sub.3. Incomplete conversion to Na.sub.3TMPP.sub.3 was determined by .sup.1H NMR, which showed the presence of free TMPPH. .sup.1H NMR (benzene-d.sub.6, 500 MHz, ppm): 1.11 (br, 12H, CH.sub.3), 1.36 (br, 4H, -CH.sub.2), 1.89 (br, 2H, -CH.sub.2).

12c. Synthesis of bis(2,2,6,6-tetramethylpiperidinato)manganese(II), Mn(TMPP)2

(76) Crushed anhydrous beads of MnCl.sub.2 (175 mg, 1.4 mmol) was refluxed for 18 hours in 10 mL of THF. Na.sub.3TMPP.sub.3 was prepared in 10 mL of hexanes as described previously (nBuNa (223 mg, 2.8 mmol); TMPPH (390 mg, 2.8 mmol); J. Organomet. Chem. 1999, 587, 88.) The freshly prepared Na.sub.3TMPP.sub.3 was added to the suspension of MnCl.sub.2(THF) in cold THF (35 C.). The reaction was allowed to warm to room temperature and stirred for 12 hours, yielding an orange-brown solution. The volatiles were removed in vacuum; the resulting oil was dissolved in hexanes (20 mL) and filtered through Celite to remove NaCl. The solvents were removed in vacuum yielding an orange-brown oil in 84% yield. .sup.1H NMR shows 3 or 4 broad paramagnetic resonances that shift their positions between 0 and 20 ppm depending on the concentration. One representative .sup.1H NMR (benzene-d.sub.6, 500 MHz, ppm): 10.84, 8.86, 4.93, 3.54. Yellow crystals were grown from hexanes (unit cell: a=11.17, b=15.08, c=16.28, =97.87, =96.86, =105.61).

Example 13. Preparation of bis(2,2,6,6-tetramethylpiperidinato)titanium(II)

(77) ##STR00029##

13a. Synthesis of Titanium Dichloride Complex with Tetramethylethylenediamine, TiCl2(TMEDA)2

(78) TiCl.sub.2(TMEDA).sub.2 was prepared using a synthesis adapted from a report in Inorganic Chemistry 1991, vol. 30, page 154. In an Ar glovebox, TMEDA (29 g, 0.25 mol) was added to a suspension of commercial (Sigma-Aldrich) TiCl.sub.3(THF).sub.3 (15 g, 0.040 mol) in THF (100 mL) at 35 C. Very thin (paper thickness), freshly hammered lithium metal foil (0.95 g, 0.14 mol) was rinsed with hexanes, prior to adding the solid chunks to the reaction at 35 C. The reaction was allowed to warm to room temperature at which point a color change occurred from a green solution to a black/brown suspension. The reaction was vigorously stirred at room temperature for no more than 24 hours, but at least overnight. A solution of TMEDA (5 mL) and THF (170 mL) was cooled to 35 C. The reaction and filter apparatus were cooled in the cold well of the glovebox at 78 C. The cold TMEDA/THF solution was added to the cold reaction and immediately filtered through Celite (cold filtration) to remove the unreacted lithium metal. The solute was transferred to a cold Schlenk flask and concentrated to a final volume of 200 mL. The schlenk flask should remain in the cold well (at 78 C.) during the concentration process. During this time, a purple precipitate should begin to form. The resulting solution was stored at 35 C. for at least 24 hours, yielding a purple precipitate that was isolated by filtration. The purple crystals were washed with 20 mL of cold (35 C.) THF. While TiCl.sub.2(TMEDA).sub.2 is stable at room temperature when isolated as a solid, it was stored in a 35 C. freezer. Isolated yield: 45%. It is imperative that the reaction is kept cold during the entire workup. In all steps, glassware and solvent should be allowed to cool for at least 1 hour to ensure the appropriate temperature has been reached. Failure to rigorously cool apparatus and solvent will result in decomposition and lower yields.

13b. Synthesis of the dimer of (2,2,6,6-tetramethylpiperidinato)sodium complex with tetramethylethylenediamine, Na2(TMPP)2(TMEDA)2

(79) The compound Na.sub.2(TMPP).sub.2(TMEDA).sub.2 was prepared following a literature procedure from Chem. Eur. J. 2008, 14, 8025. Na.sub.3(TMPP).sub.3 (175 mg, 0.41 mmol, prepared as in Example 12) was added to 5 mL hexanes. TMEDA (>5 mL) was added to the Na.sub.3(TMPP).sub.3 until the solid Na.sub.3(TMPP).sub.3 had completely dissolved in the hexanes, indicating complete conversion to Na.sub.2(TMPP).sub.2(TMEDA).sub.2. The material need not be isolated, but is prepared in situ during the synthesis of Ti(TMPP).sub.2 below. .sup.1H NMR (benzene-d.sub.6, 500 MHz, ppm): 1.43 (TMPP, br, 12H, CH.sub.3), 1.63 (TMPP, br, 4H, -CH.sub.2), 1.90 (TMEDA, br, 4H, CH.sub.2), 1.92 (TMEDA, br, 12H, CH.sub.3) 2.13 (TMP, br, 2H, -CH.sub.2).

13c. Synthesis of bis(2,2,6,6-tetramethylpiperidinato)titanium(II), Ti(TMPP)2

(80) Cold hexanes (10 mL, 35 C.) was added to solid TiCl.sub.2(TMEDA).sub.2 (130 mg, 0.37 mmol). The dissolved Na.sub.2(TMPP).sub.2(TMEDA).sub.2 was added cold (35 C.) to the suspension of TiCl.sub.2(TMEDA).sub.2 in hexanes. The reaction was allowed to warm to room temperature and stirred for at least 8 hours resulting in a brown solution. The volatiles were removed in vacuum and the resulting oil was dissolved in hexane and filtered through Celite to remove NaCl. The solute was transferred to a round bottom flask and the volatiles were removed in vacuum. The resulting brown oil was lyophilized from benzene to afford a brown solid. Isolated yield: 95 mg (80%). The .sup.1H NMR shows shifts assigned to free TMPH (.sup.1H NMR (benzene-d.sub.6, 500 MHz, ppm): 1.06 (s, 12H, CH.sub.3), 1.22 (t, 4H, -CH.sub.2), 1.53 (m, 2H, -CH.sub.2) and two resonances assigned to TMEDA, which shift depending on concentration (representative .sup.1H NMR shifts for TMEDA (benzene-d.sub.6, 500 MHz, ppm): 2.04 (br, 12H, CH.sub.3), 2.19 (t, 4H, -CH.sub.2)). Electron paramagnetic resonance (EPR) shows an anisotropic signal consistent with an impurity of Ti.sub.2Cl.sub.5(TMEDA).sub.2 having g-tensor components g.sub.xy=1.98 and g.sub.z=1.93. To evaluate how much of this chlorine-containing impurity was present, a chlorine analysis was carried out as follows: The sample combusted in a flow-through furnace (1100 C.) with platinum catalysis in an atmosphere of oxygen and moisture, and the combustion products in the effluent gas were captured in a trap filled with NaOH and H.sub.2O.sub.2. After the combustion was complete both the ash and the liquid in the trap were analyzed for chlorine ion. Weight of the sample used: 9.920 mg. Cl in the ash=0.19%; Cl in the effluent gas (liquid in the trap)=2.08%. Based on this chlorine analysis, the amount of the Ti.sub.2Cl.sub.5(TMEDA).sub.2 impurity is estimated to be only about 62 weight % of the product. The Ti(TMP).sub.2 product was purified by sublimation under high vacuum.

(81) The compounds of this invention are useful for the synthesis of materials containing metals. Examples include pure metals, metal alloys, metal oxides, metal nitrides, metal phosphides, metal sulfides, metal borides, metal silicides and metal germanides. Techniques for materials synthesis include vapor deposition (CVD and ALD), liquid solution methods (sol-gel and precipitation) and solid-state pyrolysis.

(82) Vapors useful in vapor deposition can be made by sublimation or distillation from bubblers, or by rapid evaporation of solutions in solvents. The solvents for these solutions must not react with the metal precursors, should have rates of evaporation similar to those of the metal precursors, and have melting points well below room temperature. The compounds of this invention are highly soluble in hydrocarbon solvents, such as alkanes, alkenes or terpenes. Preferred solvents include the saturated hydrocarbons dodecane, tetradecane, 2,6,10-trimethyldodecane (commonly called farnesane), 2,2,4,4,6,8,8-heptamethylnonane (commonly called cyprane), 2,6,10-trimethylpentadecane (commonly called norpristane), and 2,6,10,14-tetramethylpentadecane (commonly called pristane). Another class of suitable solvents includes trialkylamines, such as tri-n-butylamine, tri-n-pentylamine, tri-n-hexylamine, tri-n-heptylamine and tri-n-octylamine.

(83) Those skilled in the art will recognize or be able to ascertain using no more than routine experimentation, many equivalents to the specific embodiments of the invention described specifically herein. Such equivalents are intended to be encompassed within the scope of the following claims.