TOPICAL COMPOSITIONS

Abstract

The present invention relates to a topical composition comprising glycerin, microcrystalline cellulose and/or microcrystalline wax and silica beads having a particle size D.sub.v0 of greater 0.3 m, a D.sub.v100 of less than 35 m, a D.sub.v50 selected in the range of 9 to 15 m and an oil absorption capacity selected in the range of 1.2-2.5 cc/g. Furthermore the invention relates to the use of such beads in combination with microcrystalline cellulose and/or microcrystalline wax to ameliorate the short and long-term sensory properties of a topical composition comprising glycerin.

Claims

1. A topical composition comprising glycerin, microcrystalline cellulose and/or microcrystalline wax and silica beads having a particle size D.sub.v0 of greater 0.3 m, a D.sub.v100 of less than 35 m, a Dv50 selected in the range of 9 to 15 m and an oil absorption capacity selected in the range of 1.2-2.5 cc/g.

2. The topical composition according to claim 1, wherein the amount glycerin is selected in the range of 1 to 20 wt.-%, more preferably in the range of 3 to 15 wt.-%, and most preferably in the range of 5 to 10 wt.-%, based on the total weight of the composition.

3. The topical composition according to claim 1, wherein the amount of the silica beads is selected in the range of 0.5 to 10 wt.-%, preferably in the range of 1 to 5 wt.-%, and most preferably in the range of 2 to 4 wt.-%, based on the total weight of the composition.

4. The topical composition according to claim 1, wherein the total amount of microcrystalline cellulose and/or microcrystalline wax is selected in the range of 0.1 to 10 wt.-%, more preferably in the range of 0.5 to 5 wt.-%, based on the total weight of the composition.

5. The topical composition according to claim 1, wherein no microcrystalline wax is present in the topical composition.

6. The topical composition according to claim 1, wherein the oil absorption capacity is selected in the range of in the range of 1.2 to 2.0 cc/g and preferably in the range of 1.3 to 1.8 cc/g.

7. The topical composition according to claim 1, wherein the topical composition further comprises at least one oil soluble UV-filter substance.

8. The topical compositions according to claim 7, wherein the at least one oil soluble UV-filter substance is selected from the group consisting of butyl methoxy-dibenzoylmethane, octocrylene, polysilicone-15 as well as mixtures thereof.

9. The topical composition according to claim 7, wherein the total amount of the at least one additional oil soluble UV-filter substance is selected in the range of 0.1 to 25 wt.-%, preferably in the range of 1 to 20 wt.-%, most preferably in the range of 5 to 15 wt.-%, based on the total weight of the topical composition

10. The topical composition according to claim 7, wherein the composition further comprises at least one inorganic or water soluble UV-filter substance as well as mixtures thereof.

11. The topical composition according to claim 10, wherein the water soluble UV-filter substance is 2-phenylbenzimidazol-sulphonic acid and the inorganic UV-filter substance is titanium dioxide having an inner silica and an outer dimethicone coating.

12. The topical composition according to claim 1, wherein the topical composition is in the form of an oil-in-water (O/W) emulsion comprising an oily phase dispersed in an aqueous phase in the presence of an O/W emulsifier.

13. The topical composition according to claim 12, wherein the O/W emulsifier is potassium cetyl phosphate.

14. Use of silica beads having a particle size D.sub.v0 of greater than 0.3 m, a D.sub.v100 of less than 35 m, and a D.sub.v50 selected in the range of 9 to 15 m and an oil absorption capacity selected in the range of 1.2-2.5 cc/g in combination with microcrystalline cellulose and/or microcrystalline wax to reduce the stickiness of a topical composition comprising glycerin.

15. A method to reduce the stickiness of a topical composition comprising glycerin, said method comprising the step of adding to the topical composition silica beads having a particle size D.sub.v0 of greater than 0.3 m, a D.sub.v100 of less than 35 m, a Dv50 selected in the range of 9 to 15 m and an oil absorption capacity selected in the range of 1.2-2.5 cc/g in combination with microcrystalline cellulose and/or microcrystalline wax and appreciating the effect.

Description

EXAMPLE 1

Oil Absorption Capacity VALVANCETOUCH 210

[0060] About 2.0 g-2.2 g of the silica beads was weighted in a small beaker glass (20 ml) at 23 C. After addition of 4 to 5 drops of paraffin to the powder, mixing was performed using a spatula, and addition of paraffin is continued until conglomerates of oil and powder have formed. From this point, the paraffin was added one drop at a time and the mixture was then triturated with the spatula. The addition of oil was stopped when the loose and dry powder completely disappeared and a highly viscous white to transparent homogeneous gel was obtained. The oil absorption capacity (cc/g) was then calculated by the volume of paraffin used (in cc) per g of silica beads to be 1.58 cc/g.

EXAMPLE 2

Sensory Evaluation I

2.1 Formulations

[0061]

TABLE-US-00001 TABLE 1 Sunscreen SPF 30 Ingredients INCI % w/w PARSOL 1789 Butyl Methoxydibenzoylmethane 4.00 PARSOL 340 Octocrylene 8.00 PARSOL SLX Polysilicone-15 1.50 PARSOL TX Titanium Dioxide & Silica & Dimethicone 3.00 AMPHISOL K Potassium Cetyl Phosphate 2.00 Cetearyl Alcohol 0.80 C12-15 Alkyl Benzoate 3.00 Butylene Glycol Dicaprylate/Dicaprate 4.00 Dicaprylyl Carbonate 3.00 Phenoxyethanol & Ethylhexyl Glycerin 1.00 Glycerin 5.00 Xanthan Gum 0.30 Microcrystalline Cellulose 1.20 Disodium EDTA 0.10 Aqua ad 100 Tromethamine 0.25 PARSOL HS Phenylbenzimidazole Sulfonic Acid 1.50 Tromethamine 0.75 Aqua 10.00 VALVANCE Silica 1.50 Touch 210

TABLE-US-00002 TABLE 2 Sunscreen: SPF 50.sup.+ Ingredients INCI % w/w PARSOL 1789 Butyl Methoxydibenzoylmethane 5.00 PARSOL 340 Octocrylene 14.00 PARSOL SLX Polysilicone-15 2.00 PARSOL TX Titanium Dioxide & Silica & Dimethicone 3.00 AMPHISOL K Potassium Cetyl Phosphate 2.00 Cetearyl Alcohol 1.20 C12-15 Alkyl Benzoate 4.00 Diisopropyl Sebacate 8.00 Phenoxyethanol & Ethylhexyl Glycerin 1.00 Glycerin 5.00 Xanthan Gum 0.20 Microcrystalline Cellulose 0.60 Disodium EDTA 0.10 Aqua ad 100 Tromethamine 0.25 PARSOL HS Phenylbenzimidazole Sulfonic Acid 2.00 Tromethamine 1.00 Aqua 10.00 VALVANCE Silica 2.00 Touch 210

2.2 Sensory Evaluation

[0062] The formulations as outlined in Table 1 and 2 above were tested in a blind study with a trained sensorial panel consisting of 8 persons under the following conditions: The evaluation takes part on the inner forearm; the panel leader applies 50 L of the respective sample.

[0063] Evaluator spreads the product within a defined circle of 5 cm diameter using index or middle finger, circular motion, rate of 2 rotations/second. This is the so called rub-out phase. After the rub-out phase the stickiness is assessed relative to a set of standards. The stickiness is scaled on a scale from 0 to 100 in comparison to trained standards. Data are median values. The stickiness values are assessed immediately after application as well as after 20 min. As can be retrieved from table 4, the compositions according to the present invention showed a significantly reduced stickiness directly after application as well as after 20 min compared to commercially available sunscreens (listed in table 3).

TABLE-US-00003 TABLE 3 Stickiness values for commercially available sunscreens with SPF 30 and 50 Stickiness References Immediate After 20 min 1. Garnier Ambre Solaire UV Sensitive 14 10 Sonnenschutzmilch SPF 50.sup.+ 2. Nivea sun Kids Pure & Sensitive 17 10 Sonnenspray SPF 50.sup.+ 3. Soltan Once Kids Lotion 50.sup.+ 17 8 4. Ombia Suncare Spray 30 15 5 1. Garnier Ambre Solaire, UV Sensitive Sonnenschutzmilch SPF 50.sup.+ (Company: L'Oreal; purchased August 2012 in Germany); INCI: Aqua, Octocrylene, Propylene Glycol, Glycerin, Titanium dioxide, C12-15 Alkyl benzoate, Cyclopentasiloxane, Butyl Methoxydibenzoylmethane, Drometrizole Trisiloxane (Benzotriazol), Isohexadecan, Glyceryl Stearate, Potassium Cetyl Phosphate, VP/Eicosene Copolymer, Tocopherol, Phenoxyethanol, PEG-100 Stearate, Ethylparaben, Triethanolamine, Stearic Acid, Chlorphenesin, Dimethicone, Xanthan Gum, Propylparaben, Terephthalylidene Dicamphor Sulfonic Acid, Acrylates/c10-30 Alkyl Acrylate Crosspolymer, Rosa Canina Fruit Oil, Disodium Edta, Methylparaben., Butylparaben, Aluminum Hydroxide, Palmitic Acid, FIL B50529/1. 2. Nivea sun Kids Pure & Sensitive Sonnenspray SPF 50.sup.+ (Company: Beiersdorf, purchased July 2012 in Germany); INCI: Aqua, Glycerin, Octocrylene, Alcohol Denat., Butylene Glycol Dicaprylate/Dicaprate, Butyl Methoxydibenzoylmethane, Bis-Ethylhexyloxyphenol Methoxyphenyl Triazine, Homosalate, Titanium Dioxide, Ceteareth-20, C18-36 Acid Triglyceride, Methylpropanediol, Sodium Phenylbenzimidazole Sulfonate, Diethylhexyl Butamido Triazone, Ethylhexyl Methoxycinnamate, Tocopheryl Acetate, Ethylhexylglycerin, PVP/Hexadecene Copolymer, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Trimethoxycaprylylsilane, Trisodium EDTA, BHT 3. Soltan Once Kids 8 Hour Play Hypo-allergenic Suncare Lotion SPF 50+ (Company: Boots, purchased July 2012 in Switzerland); INCI: Aqua, C12-15 alkyl benzoate, Methylene bis-benzotriazolyl tetramethylbutylphenol (nano), Butyl methoxydibenzoyl-methane, Butylene glycol, Octocrylene, Tridecyl salicylate, PVP/eicosene copolymer, Bisethylhexyloxyphenol methoxyphenyl triazine, C18-36 acid glycol ester, Polyglyceryl-3 methylglucose distearate, Titanium dioxide (nano), Polysilicone-15, Decyl glucoside, Phenoxyethanol, Diethylhexyl butamido triazone, Potassium cetyl phosphate, Parfum, Tocopheryl acetate, Vitis vinifera seed oil, Acrylates/vinyl isodecanoate crosspolymer, Glycerin, Dimethyl oxazolidine, Propylene glycol, Potassium hydroxide, Xanthan gum, Tetrasodium EDTA, Manganese dioxide, Panax ginseng extract, Sodium ascorbyl phosphate, Aminomethyl propanol. 4. Ombia Suncare Spray 30 (Company: Aldi; purchased July 2012 in Germany); INCI: Aqua, Octocrylene, Alcohol, Dibutyl Adipate, Butyl Methoxydibenzoylemethane, Glyzerin, Titanium Dioxide, C12-15 Alkyl Benzoate, VP/Eicosene, Copolymer, Diethylhexyl, Methoxyphenyl, Triazine, Bisabolol, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Disodium Edta, Ethylhexyglyerin, Silica, Dimethicone.

TABLE-US-00004 TABLE 4 Stickiness values for topical compositions according to the present invention Stickiness Standard Immediate After 20 min Sunscreen SPF 30 (Table 1) 6 1 Sunscreen SPF 50+ (Table 2) 6 2

[0064] As can be retrieved from table 4, the topical compositions according to the present invention exhibit a significantly reduced stickiness directly after application as well as after 20 min compared to common market products.

EXAMPLE 3

Sensory Evaluation II

[0065] The formulations as outlined in Table 4 were tested in a blind study with a trained sensorial panel consisting of 8 persons under the following conditions:

[0066] The evaluation takes part on the inner forearm; the panel leader applies 50 L of the respective sample.

[0067] Evaluator spreads the product within a defined circle of 5 cm diameter using index or middle finger, circular motion, rate of 2 rotations/second. This is the so called rub-out phase. During this rub-out phase the rotations are counted until the product starts to absorb into skin. The amount of rotations gives a clear number how long a cosmetic product needs to absorb. The absorbency is scaled on a scale from 0 to 100 in comparison to trained standards. The smaller the value the faster absorbs the product. After the rub-out phase the stickiness is assessed relative to a set of standards. The stickiness is scaled on a scale from 0 to 100 in comparison to trained standards. Data are median values. The stickiness values are assessed after 20 min. As can be retrieved from table 4, the addition of microcrystalline wax, respectively microcrystalline cellulose leads to a significantly reduction in the stickiness after 20 min compared to the base and to the reference comprising the silica beads. Furthermore, the absorbency is also significantly improved by the addition of microcrystalline wax, respectively microcrystalline cellulose. In addition, all samples according to the invention exhibit an improved dry touch compared to the base as well as to the reference.

TABLE-US-00005 TABLE 4 INCI Base Ref Inv 1 Inv 2 Ingredients Name % w/w A Water dem. Aqua Ad 100 Ad 100 Ad 100 Ad 100 Glycerin Glycerin 11.60 11.60 11.60 11.60 1,23 (86.5%) Ph. Eur. Avicel Micro- 2.50 PC 611 crystalline cellulose Kahlwax Hydroge- 2.50 1847 nated micro- crystalline wax B AMPHISOL Potassium 1.50 1.50 1.50 1.50 K cetyl phosphate Lanette O Cetearyl 3.45 3.45 3.45 3.45 alcohol Myritol Caprylic/ 8.00 8.00 8.00 8.00 318 capric tri- glyceride Isopropyl- Isopropyl 8.00 8.00 8.00 8.00 palmitate palmitate PARSOL Octocrylene 340 C VALVANCE Slica 3.00 3.00 3.00 Touch 210 D Phenonip 0.50 0.50 0.50 0.50 XB Stickiness 1.78 0.84 0.48 0.63 after 20 min % reduction 52.8% 73.0% 64.6% in stickiness vs. Base % reduction 43% 25% in stickiness vs. Ref Absorbency 90 93 70 74 % improve- 3% 22% 18% ment in absorbency vs Base % improve- 25% 20% ment in absorbency vs Ref

EXAMPLE 4

Sunscreen: SPF 50

[0068]

TABLE-US-00006 Tradename INCI Wt.-% A PARSOL 1789 Butyl Methoxydibenzoylmethane 3.00 PARSOL 340 Octocrylene 2.70 PARSOL HMS Homosalate 15.00 PARSOL EHS Ethylhexyl Salicylate 5.00 PARSOL SLX Polysilicone-15 0.90 PARSOL MCX Ethylhexyl Methoxycinnmate 3.00 Eusolex 4360 Benzophenone-3 5.00 Amphisol K Potassium Cetyl Phosphate 2.00 Lanette O Cetearyl Alcohol 1.20 Paracera M Microcrystalline Wax 2.00 SilCare Silicone Caprylyl Methicone 2.00 41M15 BHT BHT 0.05 Euxyl PE 9010 Phenoxyethanol & Ethylhexyl 1.00 Glycerin B Glycerin 86.5% Glycerin 5.00 Keltrol CG SFT Xanthan Gum 0.20 Avicel PC 611 Microcrystalline Cellulose 0.60 Edeta BD Disodium EDTA 0.10 Water demin. Aqua Ad 100 D Allianz OPT Acrylates (and) C12-22 2.00 Alkylmethacrylate Copolymer VALVANCE Silica 2.00 Touch 210