Compositions for reprogramming cells into hemogenic and/or hematopoietic stem cell-like cells, methods and uses thereof

Abstract

The present disclosure relates to a construct or a vector for reprogramming stem cells, differentiated cells, or mixtures thereof into hemogenic and/or hematopoietic stem cell-like cells, wherein the construct or the vector encodes a peptide comprising a combination of two isolated or synthetic transcription factors, preferably at least three isolated or synthetic transcription factors. The disclosure also relates to a composition comprising said construct or vector, to a method for reprogramming or inducing a stem cell or a differentiated cell into hemogenic and/or hematopoietic stem cell-like cells comprising a step of transducing a cell with at least one of said vectors; to a induced hemogenic and/or hematopoietic stem cell-like cell obtained by said method; to a composition comprising said induced hemogenic and/or hematopoietic stem cell-like cell; and to a kit comprising at least one of the following components: the induced hemogenic and/or hematopoietic stem cell-like cell; the composition as described in any of the previous claims; the vector or the construct as disclosed; or mixtures thereof.

Claims

1. A construct or a vector for reprogramming stem cells, differentiated cells, or mixtures thereof into hemogenic and/or hematopoietic stem cell-like cells, wherein the construct or the vector encodes a peptide comprising a combination of at least three isolated or synthetic transcription factors wherein the peptide sequence is at least 90% homologous to one of a list consisting of: SEQ ID No. 11, SEQ ID No. 12, SEQ ID No. 13, SEQ ID No. 14, SEQ ID No. 15, SEQ ID No. 16, and mixtures thereof.

2. (canceled)

3. (canceled)

4. (canceled)

5. The construct or the vector according to claim 1 comprising a sequence at least 90% homologous to one of a list consisting of: SEQ ID No. 44, SEQ ID No. 45, SEQ ID No. 46, SEQ ID No. 47, SEQ ID No. 48; SEQ ID No. 49.

6. (canceled)

7. (canceled)

8. The construct or the vector according to claim 1 with a sequence at least 90% homologous to one of a list consisting of: SEQ ID No. 20, SEQ ID. No 21, SEQ ID No. 22, SEQ ID No. 23, SEQ ID No. 24, SEQ ID No. 25, or combinations thereof.

9. (canceled)

10. (canceled)

11. (canceled)

12. The construct or the vector according to claim 1 wherein the combination of three isolated or synthetic transcription factors is encoded in the following sequential order from 5 to 3: GATA2, GFI1B, FOS; or GATA2, FOS, GFI1B; or GFI1B, GATA2, FOS; or GFI1B, FOS, GATA2; FOS, GATA2, GFI1B; or FOS, GFI1B, GATA2.

13. (canceled)

14. The construct or the vector according to claim 1 for use in medicine or as medicament.

15. A composition comprising the construct or vector described in claim 1 for reprogramming stem cells, differentiated cells, or mixtures thereof into hemogenic and/or hematopoietic stem cell-like cells.

16. The composition according of claim 15, further comprising a combination of at least three transcription factors encoded by an isolated or synthetic sequence at least 90% homologous to one a list consisting of: SEQ ID No. 44, SEQ ID No. 45, SEQ ID No. 46, SEQ ID No. 47, SEQ ID No. 48, SEQ ID No. 49.

17. (canceled)

18. (canceled)

19. (canceled)

20. (canceled)

21. The composition according to claim 15 for reprogramming or inducing factor of a cell selected from a list consisting of: fibroblast, differentiated cell, and mixtures thereof, into hemogenic and/or hematopoietic stem cell-like cells.

22. The composition according to claim 15, for use in veterinary or human medicine.

23. (canceled)

24. A method for reprogramming or inducing a stem cell or a differentiated cell into hemogenic and/or hematopoietic stem cell-like cells, comprising the following steps: transducing a cell selected from a list consisting of: stem cell or a differentiated cell, and mixtures thereof, with one or more vectors comprising a nucleic acid sequence encoding an amino_acid sequence at least 90% homologous, to a sequence from a list consisting of SEQ ID No. 11, SEQ ID No. 12, SEQ ID No. 13, SEQ ID No. 14, SEQ ID No. 15, SEQ ID No. 16, and mixtures thereof; and culturing the transduced cell in a cell media that supports growth of hemogenic and/or hematopoietic stem cell-like cells.

25. (canceled)

26. (canceled)

27. (canceled)

28. (canceled)

29. (canceled)

30. (canceled)

31. The method according to claim 24, wherein the pluripotent stem cell, multipotent stem cell, or differentiated cell, is selected from the group consisting of: an endoderm derived cell, a mesoderm derived cell, or an ectoderm derived cell, a multipotent stem cell including mesenchymal stem cell, a hematopoietic stem cell, an intestinal stem cell, a cell line, or fibroblast cell.

32. (canceled)

33. (canceled)

34. (canceled)

35. (canceled)

36. An induced hemogenic and/or hematopoietic stem cell-like cell obtained by the method described in claim 24.

37. A composition comprising an induced hemogenic and/or hematopoietic stem cell-like cell described in claim 36, or mixtures thereof, in a therapeutically effective amount and a pharmaceutically acceptable excipient.

38. The composition according to claim 37 for use in veterinary or human medicine.

39. The composition according to 38 claim 37 for use in stem cell or bone marrow transplantation, immunotherapy, hemotherapy, treatment or therapy of neurodegenerative diseases, drug screening, disease modelling of blood-related diseases, treatment or therapy of autoimmune diseases, treatment or therapy of immunodeficiency, treatment or therapy of cancer, or the treatment or therapy of an infectious diseases.

40. The composition according to claim 37, further comprising an anti-viral, an analgesic, an anti-inflammatory agent, a chemotherapy agent, a radiotherapy agent, an antibiotic, a diuretic, or mixtures thereof.

41. (canceled)

42. The composition according to claim 37, wherein the composition is an injectable formulation.

43. (canceled)

44. (canceled)

45. (canceled)

46. (canceled)

47. A kit comprising one or more of the following components: the construct or vector of claim 1; and induced hemogenic and/or hematopoietic stem cell-like cells, wherein the cells have been induced into their current state by transducing stem cells, differentiated cells, or mixtures thereof, with the construct or vector of claim 1, then culturing the cells in cell media that supports growth of hemogenic and/or hematopoietic stem cell-like cells.

48. The construct or the vector according to claim 1 for use in the treatment or therapy of diseases related to stem cell or bone marrow transplantation, immunotherapy, hemotherapy, treatment or therapy of neurodegenerative diseases, drug screening, disease modelling of blood-related diseases, treatment or therapy of autoimmune diseases, treatment or therapy of immunodeficiency, treatment or therapy of cancer, or the treatment or therapy of an infectious diseases.

49. The composition according to claim 15 for use in bone marrow and stem cell transplantation, in immunotherapy, or in autoimmune diseases, immunodeficiency, or in neurodegenerative or ageing diseases, or in cancer or in infectious diseases, or as a drug screening or disease model.

Description

BRIEF DESCRIPTION OF THE DRAWINGS

[0053] The following figures provide preferred embodiments for illustrating the disclosure and should not be seen as limiting the scope of invention.

[0054] FIG. 1: (A) Schematic representation of an embodiment of the three transcription factors (3TFs) in individual delivery vectors. (B) Schematic representation of polycistronic delivery vectors encoding GATA2, GFI1B and FOS in six different orders separated by P2A and T2A self-cleaving peptides. Ga-GATA2, Gi-GF11B, Fo-FOS.

[0055] FIG. 2: Embodiment of western blot data show the expression of GATA2, GFI1B and FOS proteins 5 days after transduction of human dermal fibroblasts with the six polycistronic vectors. Calnexin (CANX) was used as loading control.

[0056] FIG. 3: Embodiment of quantification (%) of fully reprogrammed (CD9+CD49f+CD34+CD143+) cells inside the live-cell population, 15 days after human dermal fibroblasts were transduced with individual factors (3TFs) or polycistronic vectors. GaFoGi was the vector (SEQ ID No. 21) that lead to the highest increase in reprogramming efficiency (n=6-7). *p<0.05, **** p<0.0001. MeanSD is represented.

[0057] FIG. 4: Representative flow cytometry plots of CD34+CD143+ cells inside the CD9+CD49f+ population when the three transcription factors (3TFs) are expressed in human dermal fibroblasts individually (A) or in the same polycistronic vector in the GATA2-FOS-GF11B (GaFoGi, SEQ ID No. 21) order (B), 15 days after transduction. A prominent CD34+CD143+ population is evident in the GaFoGi condition.

DETAILED DESCRIPTION

[0058] The present disclosure relates to a construct or a vector for reprogramming stem cells, differentiated cells, or mixtures thereof into hemogenic and/or hematopoietic stem cell-like cells, wherein the construct or the vector encodes a peptide comprising a combination of two isolated or synthetic transcription factors, preferably at least three isolated or synthetic transcription factors. The disclosure also relates to a composition comprising said construct or vector, to a method for reprogramming or inducing a stem cell or a differentiated cell into hemogenic and/or hematopoietic stem cell-like cells comprising a step of transducing a cell with at least one of said vectors; to a induced hemogenic and/or hematopoietic stem cell-like cell obtained by said method; to a composition comprising said induced hemogenic and/or hematopoietic stem cell-like cell; and to a kit comprising at least one of the following components: the induced hemogenic and/or hematopoietic stem cell-like cell; the composition as described in any of the previous claims; the vector or the construct as disclosed; or mixtures thereof.

[0059] Also, the present disclosure provides methods to generate hemogenic and/or hematopoietic stem cell-like cells from differentiated cell types by expression of transcription factors in a polycistronic vector. Three transcription factors are sufficient to induce hemogenic/hematopoietic reprogramming of differentiate cells. Polycistronic vectors include the coding sequences of the three transcription factors in six different orders, each vector encoding a first, a second and a third transcription factor separated by a self-cleavage peptide in a single open reading frame.

[0060] In an embodiment, human embryonic kidney (HEK) 293T cells, and human dermal fibroblast (HDFs) (ScienCell) were maintained in DMEM (Dulbecco's modified Eagle's medium) supplemented with 10% (v/v) fetal bovine serum (FBS), 2 mM L-glutamine and antibiotics (penicillin and streptomycin, 10 g/ml). All cells were maintained at 37 C. and 5% (v/v) CO.sub.2. HDFs undergoing reprogramming were cultured in MyeloCult H5100 (StemCell Technologies) supplemented with 1 mM of hydrocortisone (StemCell Technologies) and antibiotic-antimycotic (1).

[0061] In an embodiment, polycistronic vectors for the human factors GATA2 (SEQ ID No. 6), GF11B (SEQ ID No. 7), and FOS (SEQ ID No. 8), with the National Centre for Biotechnology Information (NCBI) consensus sequence references CCDS3049.1, CCDS6957.1 and CCDS9841.1, respectively, were codon optimized and synthesized by Twist Bioscience in six different orders (SEQ ID No. 44, SEQ ID No. 45, SEQ ID No. 46, SEQ ID No. 47, SEQ ID No. 48, SEQ ID No. 49) and subcloned by enzymatic restriction into a constitutive lentiviral vector (FUW) with a human ubiquitin (UbC) promoter (FUW-UbC, SEQ ID No. 17). Each transcription factor is separated by a self-cleavage peptide (P2A or T2A) in a single open reading frame. The first two coding sequences lack the stop codon. Individual human factors (SEQ ID No. 1, SEQ ID No. 2, SEQ ID No. 3) were also subcloned into the FUW lentiviral vector using In-Fusion HD Cloning Kit (Takara) according to manufacturer's instructions.

[0062] In an embodiment, HEK293T cells were transfected with a mixture of 10 g transfer plasmid (polycistronic or individual vectors), 7.5 g of psPAX2 packaging vector encoding the Gag, Pol, Tat and Rev genes (SEQ ID No. 18, Addgene #12260) and 2.5 g of pMD2.G envelope vector encoding the VSV-G gene (SEQ ID No. 19, Addgene #12259). Viral supernatants were harvested after 36, 48, and 72 hours of cell culture, filtered (0.45 m) and concentrated 100-fold with with Lenti-X Virus Concentrator (Takara). GATA2, GF11B and FOS individual vectors (3TFs) were pool-produced. Different viruses used in the same experiment were produced in the same batch.

[0063] In an embodiment, 150000 HDFs were plated in 6-well plates (Falcon) prior to transduction. The next day, cells were incubated overnight with 10 L of FUW lentiviral particles (polycistronics [SEQ ID No. 20, SEQ ID No. 21, SEQ ID No. 22, SEQ ID No. 23, SEQ ID No. 24, SEQ ID No. 25] or individual vectors) in media supplemented with polybrene (8 g/ml). Cells were transduced twice in consecutive days in two independent experiments. Day 0 was considered the day of the first transduction. Cells were split 1:2 at day 4 and cultured in MyeloCult H5100 (StemCell Technologies) supplemented with 1 mM of hydrocortisone (StemCell Technologies) and antibiotic-antimycotic (1) until the end of the experiment at day 15. Media was changed twice a week.

[0064] In an embodiment, up to 1 million transduced HDFs were submitted to whole cell lysis with radioimmunoprecipitation assay (RIPA) buffer (Thermo Fisher Scientific) supplemented with 100 mM phenylmethylsulfonyl fluoride (PMSF), 1M sodium fluoride (NaF) and 1 Protease Inhibitor Cocktail (Thermo Fisher Scientific). Protein fractions were diluted 1:2 in Laemmli buffer (Bio-Rad) with 5% 2-ME (Sigma) and boiled at 98 C. for 10 min. Samples were run in Bolt 4 to 12%, Bis-Tris SDS-PAGE gels (Invitrogen) using Mini Gel Tank (Thermo Fisher Scientific) and Bolt running buffer (Invitrogen). Transfer was done in an iBlot 2 (Thermo Fisher Scientific) dry system for 7 min. Membranes were incubated overnight at 4 C. with unconjugated primary antibodies against GATA2, GF11B, FOS or Calnexin diluted according to manufacturer's instructions, washed and incubated for 45 min at room temperature with donkey anti-rabbit horseradish peroxidase-conjugated secondary antibody diluted 1:10000. Membranes were incubated with ECL prime (Amersham) for 5 min and revealed in a ChemiDoc (Bio-Rad). A similar number of cells was used in all conditions.

[0065] In an embodiment, cells were dissociated, pelleted and incubated with anti-human CD49f-PECy7, CD9-PE, CD34-AF488 antibodies diluted (1:100), together with CD143-APC (3:100) in staining buffer (phosphate-buffered saline (PBS) with 2% FBS) at 4 C. for 20 min, in the presence of mouse serum 1% (v/v). Cells were washed once, resuspended in staining buffer, stained for cell viability with 4,6-diamidino-2-phenylindole (DAPI, 1:100) and analyzed in LSR FORTESSA. Live cells were defined as DAPI negative. Flow cytometry results were analyzed using Flowjo software (version 10.6.1).

[0066] In an embodiment, comparison of means between groups was performed by one-way ANOVA followed by Bonferroni's multiple comparisons test.

[0067] In an embodiment, GATA2, GF11B and FOS transcription factors can be delivered in a single polycistronic vector. Six polycistronic vectors were generated (SEQ ID No. 20, SEQ ID No. 21, SEQ ID No. 22, SEQ ID No. 23, SEQ ID No. 24, SEQ ID No. 25), where GATA2 (Ga), GF11B (Gi) and FOS (Fo) were positioned in different orders: GaGiFo (SEQ ID No. 44), GaFoGi (SEQ ID No. 45), GiGaFo (SEQ ID No. 46), GiFoGa (SEQ ID No. 47), FoGaGi (SEQ ID No. 48) and FoGiGa (SEQ ID No. 49) (FIG. 1).

[0068] In an embodiment, western blot analysis of the expression levels of each transcription factor (TF) 5 days post-transduction, with each polycistronic vector, show that the three proteins are expressed at different levels depending on the vector used (FIG. 2). Interestingly, vector GaFoGi (SEQ ID No. 21) that lead to high levels of GATA2 and GF11B, together with low levels of FOS, resulted in an 800-fold increase in the percentage of fully reprogrammed cells, when compared to the individual factors (3TFs) (FIG. 3). Higher levels of GATA2 alone (found for SEQ ID No. 22, GiGaFo) or high levels of GFI1B plus FOS (found for SEQ ID No. 25, FoGiGa) also improved reprograming efficiency, but to a lower extent, stressing the need for higher expression levels of both GATA2 and GF11B for optimal reprogramming efficiency (FIGS. 2 and 3).

[0069] In an embodiment, reprogramming efficiency was assessed by the percentage of quadruple positive cells for CD9, CD49f, CD34 and CD143 hemogenic markers, 15 days after transduction of HDFs with 3TFs or with each of the polycistronic vectors (FIGS. 3 and 4). The obtained data indicates that even though the 3TFs condition is able to generate CD9+CD49f+ cells, these lack the CD34 marker (FIG. 4A), suggesting partial reprogramming. On the contrary, transduction with the GaFoGi polycistronic vector (SEQ ID No. 21) leads to the emergence of a cell population that is both CD143 and CD34 positive (FIG. 4B). This population accounts for approximately 40% of the CD9+CD49+ population, with the expression of CD34 being the most striking difference between conditions.

[0070] Surprisingly, the expression of GATA2, GF11B and FOS in a single polycistronic vector substantially improves hemogenic reprogramming efficiency, especially wherein the vector comprises a sequence when GATA2 is followed by FOS and then GF11B (SEQ ID No. 45, GaFoGi). Using the GaFoGi vector, as SEQ ID No. 21, leads to high expression levels of both GATA2 and GF11B proteins, which translates into the combined expression of CD9, CD49f, CD143 and, in particular, CD34 markers.

[0071] In an embodiment, the increased efficiency may be accompanied by improvement in the lineage fidelity and long-term engraftment, as assessed by transcriptional and functional levels.

[0072] Methods for the alignment of sequences for comparison are well known in the art, such methods include BLAST, FASTA and TFASTA. The BLAST algorithm (Altschul et al. (1990) J Mol Biol 215: 403-10) calculates percent sequence identity and performs a statistical analysis of the similarity between the two sequences. The software for performing BLAST analysis is publicly available through the National Centre for Biotechnology Information (NCBI). The sequence identity values, which are indicated in the present subject matter as a percentage were determined over the entire amino acid sequence, using BLAST with the default parameters.

[0073] The term comprising whenever used in this document is intended to indicate the presence of stated features, integers, steps, components, but not to preclude the presence or addition of one or more other features, integers, steps, components or groups thereof.

[0074] Those skilled in the art will recognize or be able to ascertain using no more than routine experimentation, many equivalents to the specific embodiments of the invention described herein. The scope of the present invention is not intended to be limited to the above description, but rather is as set forth in the appended claims.

[0075] Where singular forms of elements or features are used in the specification of the claims, the plural form is also included, and vice versa, if not specifically excluded. For example, the term a polysaccharide or the polysaccharide also includes the plural forms polysaccharides or the polysaccharides, and vice versa. In the claims, articles such as a, an, and the may mean one or more than one unless indicated to the contrary or otherwise evident from the context. Claims or descriptions that include or between one or more members of a group are considered satisfied if one, more than one, or all of the group members are present in, employed in, or otherwise relevant to a given product or process unless indicated to the contrary or otherwise evident from the context. The invention includes embodiments in which exactly one member of the group is present in, employed in, or otherwise relevant to a given product or process. The invention also includes embodiments in which more than one, or all of the group members are present in, employed in, or otherwise relevant to a given product or process.

[0076] Furthermore, it is to be understood that the invention encompasses all variations, combinations, and permutations in which one or more limitations, elements, clauses, descriptive terms, etc., from one or more of the claims or from relevant portions of the description is introduced into another claim. For example, any claim that is dependent on another claim can be modified to include one or more limitations found in any other claim that is dependent on the same base claim.

[0077] Furthermore, where the claims recite a composition, it is to be understood that methods of using the composition for any of the purposes disclosed herein are included, and methods of making the composition according to any of the methods of making disclosed herein or other methods known in the art are included, unless otherwise indicated or unless it would be evident to one of ordinary skilled in the art that a contradiction or inconsistency would arise.

[0078] Where ranges are given, endpoints are included. Furthermore, it is to be understood that unless otherwise indicated or otherwise evident from the context and/or the understanding of one of ordinary skill in the art, values that are expressed as ranges can assume any specific value within the stated ranges in different embodiments of the invention, to the tenth of the unit of the lower limit of the range, unless the context clearly dictates otherwise. It is also to be understood that unless otherwise indicated or otherwise evident from the context and/or the understanding of one of ordinary skill in the art, values expressed as ranges can assume any subrange within the given range, wherein the endpoints of the subrange are expressed to the same degree of accuracy as the tenth of the unit of the lower limit of the range.

[0079] The disclosure should not be seen in any way restricted to the embodiments described and a person with ordinary skill in the art will foresee many possibilities to modifications thereof. The above described embodiments are combinable.

[0080] The following claims further set out particular embodiments of the disclosure.

REFERENCES

[0081] Carey, B. W., Markoulaki, S., Hanna, J., Saha, K., Gao, Q., Mitalipova, M., & Jaenisch, R. (2009). Reprogramming of murine and human somatic cells using a single polycistronic vector. PNAS, 106(1), 2-7. [0082] Gomes, A. M., Kurochkin, I., Chang, B., Daniel, M., Law, K., Satija, N., . . . Pereira, C.-F. (2018). Cooperative Transcription Factor Induction Mediates Hemogenic Reprogramming. Cell Reports, 25(10), 2821-2835. https://doi.org/10.1016/J.celrep.2018.11.032 [0083] Karlsson, G., Rrby, E., Pina, C., Soneji, S., Reckzeh, K., Miharada, K., . . . Enver, T. (2013). Report The Tetraspanin CD9 Affords High-Purity Capture of All Murine Hematopoietic Stem Cells. Cell Reports, 4(4), 642-648. https://doi.org/10.1016/j.celrep.2013.07.020 [0084] Pereira, C. F., Chang, B., Gomes, A., Bernitz, J., Papatsenko, D., Niu, X., . . . Moore, K. A. (2016). Hematopoietic Reprogramming In Vitro Informs In Vivo Identification of Hemogenic Precursors to Definitive Hematopoietic Stem Cells. Developmental Cell, 36(5), 525-539. https://doi.org/10.1016/j.devcel.2016.02.011 [0085] Pereira, C. F., Chang, B., Qiu, J., Niu, X., Papatsenko, D., Hendry, C. E., . . . Moore, K. (2013). Induction of a Hemogenic Program in Mouse Fibroblasts. Cell Stem Cell, 13(2), 205-218. https://doi.org/10.1016/j.stem.2013.05.024 [0086] Rosa, F. F., Pires, C. F., Kurochkin, I., Ferreira, A. G., Gomes, A. M., Palma, L. G., . . . Pereira, C. (2018). Direct reprogramming of fibroblasts into antigen-presenting dendritic cells. Science Immunology, 3(30), eaau4292. [0087] Silvrio-Alves, R., Gomes, A. M., Kurochkin, I., Moore, K. A., & Pereira, C.-F. (2019). Hemogenic Reprogramming of Human Fibroblasts by Enforced Expression of Transcription Factors. Journal of Visualized Experiments, (e60112). [0088] Sommer, C. A., Stadtfeld, M., Murphy, G. J., Hochedlinger, K., Kotton, D. N., & Mostoslavsky, G. (2009). Induced Pluripotent Stem Cell Generation Using a Single Lentiviral Stem Cell Cassette. Stem Cells, 27(3), 543-549. https://doi.org/10.1634/stemcells.2008-1075 [0089] Wang, L., Liu, Z., Yin, C., Asfour, H., Chen, O., Li, Y., & Bursac, N. (2015). Stoichiometry of Gata4, Mef2c, and Tbx5 Influences the Efficiency and Quality of Induced Cardiac Myocyte Reprogramming. Circulation Research, 116(2), 237-244. https://doi.org/10.1161/CIRCRESAHA.116.305547

TABLE-US-00001 SEQUENCELISTING Nucleotideandaminoacidsequencesusedwerethefollowing(*representsastopcodon): SEQIDNo.1-GATA2 ATGGAGGTGGCGCCCGAGCAGCCGCGCTGGATGGCGCACCCGGCCGTGCTGAATGCGCAGCACCCCGACTCACACCACCCGG GCCTGGCGCACAACTACATGGAACCCGCGCAGCTGCTGCCTCCAGACGAGGTGGACGTCTTCTTCAATCACCTCGACTCGCAG GGCAACCCCTACTATGCCAACCCCGCTCACGCGCGGGCGCGCGTCTCCTACAGCCCCGCGCACGCCCGCCTGACCGGAGGCCA GATGTGCCGCCCACACTTGTTGCACAGCCCGGGTTTGCCCTGGCTGGACGGGGGCAAAGCAGCCCTCTCTGCCGCTGCGGCCC ACCACCACAACCCCTGGACCGTGAGCCCCTTCTCCAAGACGCCACTGCACCCCTCAGCTGCTGGAGGCCCTGGAGGCCCACTCT CTGTGTACCCAGGGGCTGGGGGGGGAGCGGGGGAGGCAGCGGGAGCTCAGTGGCCTCCCTCACCCCTACAGCAGCCCACT CTGGCTCCCACCTTTTCGGCTTCCCACCCACGCCACCCAAAGAAGTGTCTCCTGACCCTAGCACCACGGGGGCTGCGTCTCCAG CCTCATCTTCCGCGGGGGGTAGTGCAGCCCGAGGAGAGGACAAGGACGGCGTCAAGTACCAGGTGTCACTGACGGAGAGCA TGAAGATGGAAAGTGGCAGTCCCCTGCGCCCAGGCCTAGCTACTATGGGCACCCAGCCTGCTACACACCACCCCATCCCCACC TACCCCTCCTATGTGCCGGCGGCTGCCCACGACTACAGCAGCGGACTCTTCCACCCCGGAGGCTTCCTGGGGGGACCGGCCTC CAGCTTCACCCCTAAGCAGCGCAGCAAGGCTCGTTCCTGTTCAGAAGGCCGGGAGTGTGTCAACTGTGGGGCCACAGCCACCC CTCTCTGGCGGCGGGACGGCACCGGCCACTACCTGTGCAATGCCTGTGGCCTCTACCACAAGATGAATGGGCAGAACCGACC ACTCATCAAGCCCAAGCGAAGACTGTCGGCCGCCAGAAGAGCCGGCACCTGTTGTGCAAATTGTCAGACGACAACCACCACCT TATGGCGCCGAAACGCCAACGGGGACCCTGTCTGCAACGCCTGTGGCCTCTACTACAAGCTGCACAATGTTAACAGGCCACTG ACCATGAAGAAGGAAGGGATCCAGACTCGGAACCGGAAGATGTCCAACAAGTCCAAGAAGAGCAAGAAAGGGGCGGAGTG CTTCGAGGAGCTGTCAAAGTGCATGCAGGAGAAGTCATCCCCCTTCAGTGCAGCTGCCCTGGCTGGACACATGGCACCTGTGG GCCACCTCCCGCCCTTCAGCCACTCCGGACACATCCTGCCCACTCCGACGCCCATCCACCCCTCCTCCAGCCTCTCCTTCGGCCA CCCCCACCCGTCCAGCATGGTGACCGCCATGGGCTAG SEQIDNo.2-GFI1B ATGCCACGCTCCTTCCTGGTGAAGAGCAAGAAGGCTCACACCTACCACCAGCCCCGTGTGCAGGAAGATGAACCGCTCTGGCC TCCTGCCCTTACCCCGGTGCCCAGAGACCAGGCTCCAAGCAACAGCCCTGTCCTTAGCACTCTATTCCCAAACCAGTGCCTGGA CTGGACCAACCTCAAACGAGAGCCGGAGCTGGAGCAGGACCAGAACTTGGCCAGGATGGCCCCGGCACCAGAGGGCCCCAT TGTGCTGTCCCGACCCCAGGATGGGGACTCTCCACTGTCCGACTCACCCCCATTCTACAAGCCTAGCTTCTCCTGGGACACCTT GGCCACAACCTATGGCCACAGCTACCGGCAGGCCCCCTCCACCATGCAGTCAGCCTTCCTGGAGCACTCCGTCAGCCTGTACG GCAGTCCTCTTGTGCCCAGCACTGAGCCCGCCTTGGACTTCAGCCTCCGCTACTCCCCAGGCATGGATGCGTACCACTGTGTGA AGTGCAACAAGGTCTTCTCCACCCCTCACGGGCTCGAAGTGCATGTGCGACGCTCCCATAGTGGGACCCGGCCCTTCGCCTGT GACATCTGCGGCAAAACCTTCGGCCACGCTGTGAGCCTGGAGCAGCACACGCACGTCCACTCCCAGGAGCGCAGCTTCGAGT GCCGCATGTGCGGCAAGGCCTTCAAGCGCTCGTCCACGCTGTCCACCCACCTGCTCATCCACTCAGACACGCGGCCCTACCCCT GCCAGTTCTGCGGCAAGCGTTTCCACCAGAAGTCCGACATGAAGAAGCACACCTACATCCACACAGGTGAGAAGCCGCACAA GTGCCAGGTGTGCGGAAAGGCCTTCAGCCAGAGCTCCAACCTCATCACCCACAGCCGCAAGCACACAGGCTTCAAGCCCTTCA GCTGTGAGCTGTGCACCAAAGGCTTCCAGCGCAAGGTGGACCTGCGGCGGCACCGCGAGAGCCAGCACAATCTCAAGTGA SEQIDNo.3-FOS ATGATGTTCTCGGGCTTCAACGCAGACTACGAGGCGTCATCCTCCCGCTGCAGCAGCGCGTCCCCGGCCGGGGATAGCCTCTC TTACTACCACTCACCCGCAGACTCCTTCTCCAGCATGGGCTCGCCTGTCAACGCGCAGGACTTCTGCACGGACCTGGCCGTCTC CAGTGCCAACTTCATTCCCACGGTCACTGCCATCTCGACCAGTCCGGACCTGCAGTGGCTGGTGCAGCCCGCCCTCGTCTCCTC CGTGGCCCCATCGCAGACCAGAGCCCCTCACCCTTTCGGAGTCCCCGCCCCCTCCGCTGGGGCTTACTCCAGGGCTGGCGTTGT GAAGACCATGACAGGAGGCCGAGCGCAGAGCATTGGCAGGAGGGGCAAGGTGGAACAGTTATCTCCAGAAGAAGAAGAGA AAAGGAGAATCCGAAGGGAAAGGAATAAGATGGCTGCAGCCAAATGCCGCAACCGGAGGAGGGAGCTGACTGATACACTCC AAGCGGAGACAGACCAACTAGAAGATGAGAAGTCTGCTTTGCAGACCGAGATTGCCAACCTGCTGAAGGAGAAGGAAAAAC TAGAGTTCATCCTGGCAGCTCACCGACCTGCCTGCAAGATCCCTGATGACCTGGGCTTCCCAGAAGAGATGTCTGTGGCTTCCC TTGATCTGACTGGGGGCCTGCCAGAGGTTGCCACCCCGGAGTCTGAGGAGGCCTTCACCCTGCCTCTCCTCAATGACCCTGAG CCCAAGCCCTCAGTGGAACCTGTCAAGAGCATCAGCAGCATGGAGCTGAAGACCGAGCCCTTTGATGACTTCCTGTTCCCAGC ATCATCCAGGCCCAGTGGCTCTGAGACAGCCCGCTCCGTGCCAGACATGGACCTATCTGGGTCCTTCTATGCAGCAGACTGGG AGCCTCTGCACAGTGGCTCCCTGGGGATGGGGCCCATGGCCACAGAGCTGGAGCCCCTGTGCACTCCGGTGGTCACCTGTACT CCCAGCTGCACTGCTTACACGTCTTCCTTCGTCTTCACCTACCCCGAGGCTGACTCCTTCCCCAGCTGTGCAGCTGCCCACCGCA AGGGCAGCAGCAGCAATGAGCCTTCCTCTGACTCGCTCAGCTCACCCACGCTGCTGGCCCTGTGA SEQIDNo.4-P2A GCCACAAACTTCTCTCTGCTAAAGCAAGCAGGTGATGTTGAAGAAAACCCCGGGCCT SEQIDNo.5-T2A GAGGGCAGGGGAAGTCTTCTAACATGCGGGGACGTGGAGGAAAATCCCGGCCCA SEQIDNo.6-GATA2peptide MEVAPEQPRWMAHPAVLNAQHPDSHHPGLAHNYMEPAQLLPPDEVDVFFNHLDSQGNPYYANPAHARARVSYSPAHARLTGG QMCRPHLLHSPGLPWLDGGKAALSAAAAHHHNPWTVSPFSKTPLHPSAAGGPGGPLSVYPGAGGGSGGGSGSSVASLTPTAAHS GSHLFGFPPTPPKEVSPDPSTTGAASPASSSAGGSAARGEDKDGVKYQVSLTESMKMESGSPLRPGLATMGTQPATHHPIPTYPSY VPAAAHDYSSGLFHPGGFLGGPASSFTPKQRSKARSCSEGRECVNCGATATPLWRRDGTGHYLCNACGLYHKMNGQNRPLIKPKR RLSAARRAGTCCANCQTTTTTLWRRNANGDPVCNACGLYYKLHNVNRPLTMKKEGIQTRNRKMSNKSKKSKKGAECFEELSKCM QEKSSPFSAAALAGHMAPVGHLPPFSHSGHILPTPTPIHPSSSLSFGHPHPSSMVTAMG* SEQIDNo.7-GFI1Bpeptide MPRSFLVKSKKAHTYHQPRVQEDEPLWPPALTPVPRDQAPSNSPVLSTLFPNQCLDWTNLKREPELEQDQNLARMAP APEGPIVLSRPQDGDSPLSDSPPFYKPSFSWDTLATTYGHSYRQAPSTMQSAFLEHSVSLYGSPLVPSTEPALDFSLRYSP GMDAYHCVKCNKVFSTPHGLEVHVRRSHSGTRPFACDICGKTFGHAVSLEQHTHVHSQERSFECRMCGKAFKRSSTLS THLLIHSDTRPYPCQFCGKRFHQKSDMKKHTYIHTGEKPHKCQVCGKAFSQSSNLITHSRKHTGFKPFSCELCTKGFQRK VDLRRHRESQHNLK* SEQIDNo.8-FOSpeptide MMFSGFNADYEASSSRCSSASPAGDSLSYYHSPADSFSSMGSPVNAQDFCTDLAVSSANFIPTVTAISTSPDLQWLVQP ALVSSVAPSQTRAPHPFGVPAPSAGAYSRAGVVKTMTGGRAQSIGRRGKVEQLSPEEEEKRRIRRERNKMAAAKCRNR RRELTDTLQAETDQLEDEKSALQTEIANLLKEKEKLEFILAAHRPACKIPDDLGFPEEMSVASLDLTGGLPEVATPESEEAF TLPLLNDPEPKPSVEPVKSISSMELKTEPFDDFLFPASSRPSGSETARSVPDMDLSGSFYAADWEPLHSGSLGMGPMAT ELEPLCTPVVTCTPSCTAYTSSFVFTYPEADSFPSCAAAHRKGSSSNEPSSDSLSSPTLLAL* SEQIDNo.9-P2Aself-cleavagepeptide ATNFSLLKQAGDVEENPGP SEQIDNo.10-T2Aself-cleavagepeptide EGRGSLLTCGDVEENPGP SEQIDNo.11-GaGiFopeptide MEVAPEQPRWMAHPAVLNAQHPDSHHPGLAHNYMEPAQLLPPDEVDVFFNHLDSQGNPYYANPAHARARVSYSP AHARLTGGQMCRPHLLHSPGLPWLDGGKAALSAAAAHHHNPWTVSPFSKTPLHPSAAGGPGGPLSVYPGAGGGSG GGSGSSVASLTPTAAHSGSHLFGFPPTPPKEVSPDPSTTGAASPASSSAGGSAARGEDKDGVKYQVSLTESMKMESGSP LRPGLATMGTQPATHHPIPTYPSYVPAAAHDYSSGLFHPGGFLGGPASSFTPKQRSKARSCSEGRECVNCGATATPLW RRDGTGHYLCNACGLYHKMNGQNRPLIKPKRRLSAARRAGTCCANCQTTTTTLWRRNANGDPVCNACGLYYKLHNV NRPLTMKKEGIQTRNRKMSNKSKKSKKGAECFEELSKCMQEKSSPFSAAALAGHMAPVGHLPPFSHSGHILPTPTPIHP SSSLSFGHPHPSSMVTAMGGSGATNFSLLKQAGDVEENPGPMPRSFLVKSKKAHTYHQPRVQEDEPLWPPALTPVPR DQAPSNSPVLSTLFPNQCLDWTNLKREPELEQDQNLARMAPAPEGPIVLSRPQDGDSPLSDSPPFYKPSFSWDTLATTY GHSYRQAPSTMQSAFLEHSVSLYGSPLVPSTEPALDFSLRYSPGMDAYHCVKCNKVFSTPHGLEVHVRRSHSGTRPFAC DICGKTFGHAVSLEQHTHVHSQERSFECRMCGKAFKRSSTLSTHLLIHSDTRPYPCQFCGKRFHQKSDMKKHTYIHTGE KPHKCQVCGKAFSQSSNLITHSRKHTGFKPFSCELCTKGFQRKVDLRRHRESQHNLKGSGEGRGSLLTCGDVEENPGP MMFSGFNADYEASSSRCSSASPAGDSLSYYHSPADSFSSMGSPVNAQDFCTDLAVSSANFIPTVTAISTSPDLQWLVQP ALVSSVAPSQTRAPHPFGVPAPSAGAYSRAGVVKTMTGGRAQSIGRRGKVEQLSPEEEEKRRIRRERNKMAAAKCRNR RRELTDTLQAETDQLEDEKSALQTEIANLLKEKEKLEFILAAHRPACKIPDDLGFPEEMSVASLDLTGGLPEVATPESEEAF TLPLLNDPEPKPSVEPVKSISSMELKTEPFDDFLFPASSRPSGSETARSVPDMDLSGSFYAADWEPLHSGSLGMGPMAT ELEPLCTPVVTCTPSCTAYTSSFVFTYPEADSFPSCAAAHRKGSSSNEPSSDSLSSPTLLAL* SEQIDNo.12-GaFoGipeptide MEVAPEQPRWMAHPAVLNAQHPDSHHPGLAHNYMEPAQLLPPDEVDVFFNHLDSQGNPYYANPAHARARVSYSP AHARLTGGQMCRPHLLHSPGLPWLDGGKAALSAAAAHHHNPWTVSPFSKTPLHPSAAGGPGGPLSVYPGAGGGSG GGSGSSVASLTPTAAHSGSHLFGFPPTPPKEVSPDPSTTGAASPASSSAGGSAARGEDKDGVKYQVSLTESMKMESGSP LRPGLATMGTQPATHHPIPTYPSYVPAAAHDYSSGLFHPGGFLGGPASSFTPKQRSKARSCSEGRECVNCGATATPLW RRDGTGHYLCNACGLYHKMNGQNRPLIKPKRRLSAARRAGTCCANCQTTTTTLWRRNANGDPVCNACGLYYKLHNV NRPLTMKKEGIQTRNRKMSNKSKKSKKGAECFEELSKCMQEKSSPFSAAALAGHMAPVGHLPPFSHSGHILPTPTPIHP SSSLSFGHPHPSSMVTAMGGSGATNFSLLKQAGDVEENPGPMMFSGFNADYEASSSRCSSASPAGDSLSYYHSPADSF SSMGSPVNAQDFCTDLAVSSANFIPTVTAISTSPDLQWLVQPALVSSVAPSQTRAPHPFGVPAPSAGAYSRAGVVKTM TGGRAQSIGRRGKVEQLSPEEEEKRRIRRERNKMAAAKCRNRRRELTDTLQAETDQLEDEKSALQTEIANLLKEKEKLEFI LAAHRPACKIPDDLGFPEEMSVASLDLTGGLPEVATPESEEAFTLPLLNDPEPKPSVEPVKSISSMELKTEPFDDFLFPASS RPSGSETARSVPDMDLSGSFYAADWEPLHSGSLGMGPMATELEPLCTPVVTCTPSCTAYTSSFVFTYPEADSFPSCAAA HRKGSSSNEPSSDSLSSPTLLALGSGEGRGSLLTCGDVEENPGPMPRSFLVKSKKAHTYHQPRVQEDEPLWPPALTPVP RDQAPSNSPVLSTLFPNQCLDWTNLKREPELEQDQNLARMAPAPEGPIVLSRPQDGDSPLSDSPPFYKPSFSWDTLAT TYGHSYRQAPSTMQSAFLEHSVSLYGSPLVPSTEPALDFSLRYSPGMDAYHCVKCNKVFSTPHGLEVHVRRSHSGTRPF ACDICGKTFGHAVSLEQHTHVHSQERSFECRMCGKAFKRSSTLSTHLLIHSDTRPYPCQFCGKRFHQKSDMKKHTYIHT GEKPHKCQVCGKAFSQSSNLITHSRKHTGFKPFSCELCTKGFQRKVDLRRHRESQHNLK* SEQIDNo.13-GiGaFopeptide MPRSFLVKSKKAHTYHQPRVQEDEPLWPPALTPVPRDQAPSNSPVLSTLFPNQCLDWTNLKREPELEQDQNLARMAP APEGPIVLSRPQDGDSPLSDSPPFYKPSFSWDTLATTYGHSYRQAPSTMQSAFLEHSVSLYGSPLVPSTEPALDFSLRYSP GMDAYHCVKCNKVFSTPHGLEVHVRRSHSGTRPFACDICGKTFGHAVSLEQHTHVHSQERSFECRMCGKAFKRSSTLS THLLIHSDTRPYPCQFCGKRFHQKSDMKKHTYIHTGEKPHKCQVCGKAFSQSSNLITHSRKHTGFKPFSCELCTKGFQRK VDLRRHRESQHNLKGSGATNFSLLKQAGDVEENPGPMEVAPEQPRWMAHPAVLNAQHPDSHHPGLAHNYMEPAQ LLPPDEVDVFFNHLDSQGNPYYANPAHARARVSYSPAHARLTGGQMCRPHLLHSPGLPWLDGGKAALSAAAAHHHN PWTVSPFSKTPLHPSAAGGPGGPLSVYPGAGGGSGGGSGSSVASLTPTAAHSGSHLFGFPPTPPKEVSPDPSTTGAASP ASSSAGGSAARGEDKDGVKYQVSLTESMKMESGSPLRPGLATMGTQPATHHPIPTYPSYVPAAAHDYSSGLFHPGGFL GGPASSFTPKQRSKARSCSEGRECVNCGATATPLWRRDGTGHYLCNACGLYHKMNGQNRPLIKPKRRLSAARRAGTC CANCQTTTTTLWRRNANGDPVCNACGLYYKLHNVNRPLTMKKEGIQTRNRKMSNKSKKSKKGAECFEELSKCMQEKS SPFSAAALAGHMAPVGHLPPFSHSGHILPTPTPIHPSSSLSFGHPHPSSMVTAMGGSGEGRGSLLTCGDVEENPGPM MFSGFNADYEASSSRCSSASPAGDSLSYYHSPADSFSSMGSPVNAQDFCTDLAVSSANFIPTVTAISTSPDLQWLVQPA LVSSVAPSQTRAPHPFGVPAPSAGAYSRAGVVKTMTGGRAQSIGRRGKVEQLSPEEEEKRRIRRERNKMAAAKCRNRR RELTDTLQAETDQLEDEKSALQTEIANLLKEKEKLEFILAAHRPACKIPDDLGFPEEMSVASLDLTGGLPEVATPESEEAFT LPLLNDPEPKPSVEPVKSISSMELKTEPFDDFLFPASSRPSGSETARSVPDMDLSGSFYAADWEPLHSGSLGMGPMATE LEPLCTPVVTCTPSCTAYTSSFVFTYPEADSFPSCAAAHRKGSSSNEPSSDSLSSPTLLAL* SEQIDNo.14-GiFoGapeptide MPRSFLVKSKKAHTYHQPRVQEDEPLWPPALTPVPRDQAPSNSPVLSTLFPNQCLDWTNLKREPELEQDQNLARMAP APEGPIVLSRPQDGDSPLSDSPPFYKPSFSWDTLATTYGHSYRQAPSTMQSAFLEHSVSLYGSPLVPSTEPALDFSLRYSP GMDAYHCVKCNKVFSTPHGLEVHVRRSHSGTRPFACDICGKTFGHAVSLEQHTHVHSQERSFECRMCGKAFKRSSTLS THLLIHSDTRPYPCQFCGKRFHQKSDMKKHTYIHTGEKPHKCQVCGKAFSQSSNLITHSRKHTGFKPFSCELCTKGFQRK VDLRRHRESQHNLKGSGATNFSLLKQAGDVEENPGPMMFSGFNADYEASSSRCSSASPAGDSLSYYHSPADSFSSMGS PVNAQDFCTDLAVSSANFIPTVTAISTSPDLQWLVQPALVSSVAPSQTRAPHPFGVPAPSAGAYSRAGVVKTMTGGRA QSIGRRGKVEQLSPEEEEKRRIRRERNKMAAAKCRNRRRELTDTLQAETDQLEDEKSALQTEIANLLKEKEKLEFILAAHR PACKIPDDLGFPEEMSVASLDLTGGLPEVATPESEEAFTLPLLNDPEPKPSVEPVKSISSMELKTEPFDDFLFPASSRPSGS ETARSVPDMDLSGSFYAADWEPLHSGSLGMGPMATELEPLCTPVVTCTPSCTAYTSSFVFTYPEADSFPSCAAAHRKGS SSNEPSSDSLSSPTLLALGSGEGRGSLLTCGDVEENPGPMEVAPEQPRWMAHPAVLNAQHPDSHHPGLAHNYMEPA QLLPPDEVDVFFNHLDSQGNPYYANPAHARARVSYSPAHARLTGGQMCRPHLLHSPGLPWLDGGKAALSAAAAHHH NPWTVSPFSKTPLHPSAAGGPGGPLSVYPGAGGGSGGGSGSSVASLTPTAAHSGSHLFGFPPTPPKEVSPDPSTTGAA SPASSSAGGSAARGEDKDGVKYQVSLTESMKMESGSPLRPGLATMGTQPATHHPIPTYPSYVPAAAHDYSSGLFHPGG FLGGPASSFTPKQRSKARSCSEGRECVNCGATATPLWRRDGTGHYLCNACGLYHKMNGQNRPLIKPKRRLSAARRAGT CCANCQTTTTTLWRRNANGDPVCNACGLYYKLHNVNRPLTMKKEGIQTRNRKMSNKSKKSKKGAECFEELSKCMQEK SSPFSAAALAGHMAPVGHLPPFSHSGHILPTPTPIHPSSSLSFGHPHPSSMVTAMG* SEQIDNo.15-FoGaGipeptide MMFSGFNADYEASSSRCSSASPAGDSLSYYHSPADSFSSMGSPVNAQDFCTDLAVSSANFIPTVTAISTSPDLQWLVQP ALVSSVAPSQTRAPHPFGVPAPSAGAYSRAGVVKTMTGGRAQSIGRRGKVEQLSPEEEEKRRIRRERNKMAAAKCRNR RRELTDTLQAETDQLEDEKSALQTEIANLLKEKEKLEFILAAHRPACKIPDDLGFPEEMSVASLDLTGGLPEVATPESEEAF TLPLLNDPEPKPSVEPVKSISSMELKTEPFDDFLFPASSRPSGSETARSVPDMDLSGSFYAADWEPLHSGSLGMGPMAT ELEPLCTPVVTCTPSCTAYTSSFVFTYPEADSFPSCAAAHRKGSSSNEPSSDSLSSPTLLALGSGATNFSLLKQAGDVEENP GPMEVAPEQPRWMAHPAVLNAQHPDSHHPGLAHNYMEPAQLLPPDEVDVFFNHLDSQGNPYYANPAHARARVSY SPAHARLTGGQMCRPHLLHSPGLPWLDGGKAALSAAAAHHHNPWTVSPFSKTPLHPSAAGGPGGPLSVYPGAGGGS GGGSGSSVASLTPTAAHSGSHLFGFPPTPPKEVSPDPSTTGAASPASSSAGGSAARGEDKDGVKYQVSLTESMKMESG SPLRPGLATMGTQPATHHPIPTYPSYVPAAAHDYSSGLFHPGGFLGGPASSFTPKQRSKARSCSEGRECVNCGATATPL WRRDGTGHYLCNACGLYHKMNGQNRPLIKPKRRLSAARRAGTCCANCQTTTTTLWRRNANGDPVCNACGLYYKLH NVNRPLTMKKEGIQTRNRKMSNKSKKSKKGAECFEELSKCMQEKSSPFSAAALAGHMAPVGHLPPFSHSGHILPTPTPI HPSSSLSFGHPHPSSMVTAMGGSGEGRGSLLTCGDVEENPGPMPRSFLVKSKKAHTYHQPRVQEDEPLWPPALTPVP RDQAPSNSPVLSTLFPNQCLDWTNLKREPELEQDQNLARMAPAPEGPIVLSRPQDGDSPLSDSPPFYKPSFSWDTLAT TYGHSYRQAPSTMQSAFLEHSVSLYGSPLVPSTEPALDFSLRYSPGMDAYHCVKCNKVFSTPHGLEVHVRRSHSGTRPF ACDICGKTFGHAVSLEQHTHVHSQERSFECRMCGKAFKRSSTLSTHLLIHSDTRPYPCQFCGKRFHQKSDMKKHTYIHT GEKPHKCQVCGKAFSQSSNLITHSRKHTGFKPFSCELCTKGFQRKVDLRRHRESQHNLK* SEQIDNo.16-FoGiGapeptide MMFSGFNADYEASSSRCSSASPAGDSLSYYHSPADSFSSMGSPVNAQDFCTDLAVSSANFIPTVTAISTSPDLQWLVQP ALVSSVAPSQTRAPHPFGVPAPSAGAYSRAGVVKTMTGGRAQSIGRRGKVEQLSPEEEEKRRIRRERNKMAAAKCRNR RRELTDTLQAETDQLEDEKSALQTEIANLLKEKEKLEFILAAHRPACKIPDDLGFPEEMSVASLDLTGGLPEVATPESEEAF TLPLLNDPEPKPSVEPVKSISSMELKTEPFDDFLFPASSRPSGSETARSVPDMDLSGSFYAADWEPLHSGSLGMGPMAT ELEPLCTPVVTCTPSCTAYTSSFVFTYPEADSFPSCAAAHRKGSSSNEPSSDSLSSPTLLALGSGATNFSLLKQAGDVEENP GPMPRSFLVKSKKAHTYHQPRVQEDEPLWPPALTPVPRDQAPSNSPVLSTLFPNQCLDWTNLKREPELEQDQNLARM APAPEGPIVLSRPQDGDSPLSDSPPFYKPSFSWDTLATTYGHSYRQAPSTMQSAFLEHSVSLYGSPLVPSTEPALDFSLRY SPGMDAYHCVKCNKVFSTPHGLEVHVRRSHSGTRPFACDICGKTFGHAVSLEQHTHVHSQERSFECRMCGKAFKRSST LSTHLLIHSDTRPYPCQFCGKRFHQKSDMKKHTYIHTGEKPHKCQVCGKAFSQSSNLITHSRKHTGFKPFSCELCTKGFQ RKVDLRRHRESQHNLKGSGEGRGSLLTCGDVEENPGPMEVAPEQPRWMAHPAVLNAQHPDSHHPGLAHNYMEPA QLLPPDEVDVFFNHLDSQGNPYYANPAHARARVSYSPAHARLTGGQMCRPHLLHSPGLPWLDGGKAALSAAAAHHH NPWTVSPFSKTPLHPSAAGGPGGPLSVYPGAGGGSGGGSGSSVASLTPTAAHSGSHLFGFPPTPPKEVSPDPSTTGAA SPASSSAGGSAARGEDKDGVKYQVSLTESMKMESGSPLRPGLATMGTQPATHHPIPTYPSYVPAAAHDYSSGLFHPGG FLGGPASSFTPKQRSKARSCSEGRECVNCGATATPLWRRDGTGHYLCNACGLYHKMNGQNRPLIKPKRRLSAARRAGT CCANCQTTTTTLWRRNANGDPVCNACGLYYKLHNVNRPLTMKKEGIQTRNRKMSNKSKKSKKGAECFEELSKCMQEK SSPFSAAALAGHMAPVGHLPPFSHSGHILPTPTPIHPSSSLSFGHPHPSSMVTAMG* SEQIDNo.17-FUW-UbC TCGACGGATCGGGAGATCTCCCGATCCCCTATGGTGCACTCTCAGTACAATCTGCTCTGATGCCGCATAGTTAAGCCAGTATCT GCTCCCTGCTTGTGTGTTGGAGGTCGCTGAGTAGTGCGCGAGCAAAATTTAAGCTACAACAAGGCAAGGCTTGACCGACAATT GCATGAAGAATCTGCTTAGGGTTAGGCGTTTTGCGCTGCTTCGCGATGTACGGGCCAGATATACGCGTTGACATTGATTATTG ACTAGTTATTAATAGTAATCAATTACGGGGTCATTAGTTCATAGCCCATATATGGAGTTCCGCGTTACATAACTTACGGTAAAT GGCCCGCCTGGCTGACCGCCCAACGACCCCCGCCCATTGACGTCAATAATGACGTATGTTCCCATAGTAACGCCAATAGGGAC TTTCCATTGACGTCAATGGGTGGAGTATTTACGGTAAACTGCCCACTTGGCAGTACATCAAGTGTATCATATGCCAAGTACGCC CCCTATTGACGTCAATGACGGTAAATGGCCCGCCTGGCATTATGCCCAGTACATGACCTTATGGGACTTTCCTACTTGGCAGTA CATCTACGTATTAGTCATCGCTATTACCATGGTGATGCGGTTTTGGCAGTACATCAATGGGCGTGGATAGCGGTTTGACTCACG GGGATTTCCAAGTCTCCACCCCATTGACGTCAATGGGAGTTTGTTTTGGCACCAAAATCAACGGGACTTTCCAAAATGTCGTAA CAACTCCGCCCCATTGACGCAAATGGGCGGTAGGCGTGTACGGTGGGAGGTCTATATAAGCAGCGCGTTTTGCCTGTACTGG GTCTCTCTGGTTAGACCAGATCTGAGCCTGGGAGCTCTCTGGCTAACTAGGGAACCCACTGCTTAAGCCTCAATAAAGCTTGCC TTGAGTGCTTCAAGTAGTGTGTGCCCGTCTGTTGTGTGACTCTGGTAACTAGAGATCCCTCAGACCCTTTTAGTCAGTGTGGAA AATCTCTAGCAGTGGCGCCCGAACAGGGACTTGAAAGCGAAAGGGAAACCAGAGGAGCTCTCTCGACGCAGGACTCGGCTTG CTGAAGCGCGCACGGCAAGAGGCGAGGGGCGGCGACTGGTGAGTACGCCAAAAATTTTGACTAGCGGAGGCTAGAAGGAG AGAGATGGGTGCGAGAGCGTCAGTATTAAGCGGGGGAGAATTAGATCGCGATGGGAAAAAATTCGGTTAAGGCCAGGGGG AAAGAAAAAATATAAATTAAAACATATAGTATGGGCAAGCAGGGAGCTAGAACGATTCGCAGTTAATCCTGGCCTGTTAGAA ACATCAGAAGGCTGTAGACAAATACTGGGACAGCTACAACCATCCCTTCAGACAGGATCAGAAGAACTTAGATCATTATATAA TACAGTAGCAACCCTCTATTGTGTGCATCAAAGGATAGAGATAAAAGACACCAAGGAAGCTTTAGACAAGATAGAGGAAGAG CAAAACAAAAGTAAGACCACCGCACAGCAAGCGGCCGCTGATCTTCAGACCTGGAGGAGGAGATATGAGGGACAATTGGAG AAGTGAATTATATAAATATAAAGTAGTAAAAATTGAACCATTAGGAGTAGCACCCACCAAGGCAAAGAGAAGAGTGGTGCAG AGAGAAAAAAGAGCAGTGGGAATAGGAGCTTTGTTCCTTGGGTTCTTGGGAGCAGCAGGAAGCACTATGGGCGCAGCGTCA ATGACGCTGACGGTACAGGCCAGACAATTATTGTCTGGTATAGTGCAGCAGCAGAACAATTTGCTGAGGGCTATTGAGGCGC AACAGCATCTGTTGCAACTCACAGTCTGGGGCATCAAGCAGCTCCAGGCAAGAATCCTGGCTGTGGAAAGATACCTAAAGGAT CAACAGCTCCTGGGGATTTGGGGTTGCTCTGGAAAACTCATTTGCACCACTGCTGTGCCTTGGAATGCTAGTTGGAGTAATAA ATCTCTGGAACAGATTTGGAATCACACGACCTGGATGGAGTGGGACAGAGAAATTAACAATTACACAAGCTTAATACACTCCT TAATTGAAGAATCGCAAAACCAGCAAGAAAAGAATGAACAAGAATTATTGGAATTAGATAAATGGGCAAGTTTGTGGAATTG GTTTAACATAACAAATTGGCTGTGGTATATAAAATTATTCATAATGATAGTAGGAGGCTTGGTAGGTTTAAGAATAGTTTTTGC TGTACTTTCTATAGTGAATAGAGTTAGGCAGGGATATTCACCATTATCGTTTCAGACCCACCTCCCAACCCCGAGGGGACCCGA CAGGCCCGAAGGAATAGAAGAAGAAGGTGGAGAGAGAGACAGAGACAGATCCATTCGATTAGTGAACGGATCGGCACTGC GTGCGCCAATTCTGCAGACAAATGGCAGTATTCATCCACAATTTTAAAAGAAAAGGGGGGATTGGGGGGTACAGTGCAGGGG AAAGAATAGTAGACATAATAGCAACAGACATACAAACTAAAGAATTACAAAAACAAATTACAAAAATTCAAAATTTTCGGGTT TATTACAGGGACAGCAGAGATCCAGTTTGGTTAATTAACCCGTGTCGGCTCCAGATCTGGCCTCCGCGCCGGGTTTTGGCGCC TCCCGCGGGCGCCCCCCTCCTCACGGCGAGCGCTGCCACGTCAGACGAAGGGCGCAGCGAGCGTCCTGATCCTTCCGCCCGG ACGCTCAGGACAGCGGCCCGCTGCTCATAAGACTCGGCCTTAGAACCCCAGTATCAGCAGAAGGACATTTTAGGACGGGACTT GGGTGACTCTAGGGCACTGGTTTTCTTTCCAGAGAGCGGAACAGGCGAGGAAAAGTAGTCCCTTCTCGGCGATTCTGCGGAG GGATCTCCGTGGGGCGGTGAACGCCGATGATTATATAAGGACGCGCCGGGTGTGGCACAGCTAGTTCCGTCGCAGCCGGGAT TTGGGTCGCGGTTCTTGTTTGTGGATCGCTGTGATCGTCACTTGGTGAGTAGCGGGCTGCTGGGCTGGCCGGGGCTTTCGTGG CCGCCGGGCCGCTCGGTGGGACGGAAGCGTGTGGAGAGACCGCCAAGGGCTGTAGTCTGGGTCCGCGAGCAAGGTTGCCCT GAACTGGGGGTTGGGGGGAGCGCAGCAAAATGGCGGCTGTTCCCGAGTCTTGAATGGAAGACGCTTGTGAGGCGGGCTGTG AGGTCGTTGAAACAAGGTGGGGGGCATGGTGGGCGGCAAGAACCCAAGGTCTTGAGGCCTTCGCTAATGCGGGAAAGCTCT TATTCGGGTGAGATGGGCTGGGGCACCATCTGGGGACCCTGACGTGAAGTTTGTCACTGACTGGAGAACTCGGTTTGTCGTCT GTTGCGGGGGGGGCAGTTATGGCGGTGCCGTTGGGCAGTGCACCCGTACCTTTGGGAGCGCGCGCCCTCGTCGTGTCGTGAC GTCACCCGTTCTGTTGGCTTATAATGCAGGGTGGGGCCACCTGCCGGTAGGTGTGCGGTAGGCTTTTCTCCGTCGCAGGACGC AGGGTTCGGGCCTAGGGTAGGCTCTCCTGAATCGACAGGCGCCGGACCTCTGGTGAGGGGAGGGATAAGTGAGGCGTCAGT TTCTTTGGTCGGTTTTATGTACCTATCTTCTTAAGTAGCTGAAGCTCCGGTTTTGAACTATGCGCTCGGGGTTGGCGAGTGTGTT TTGTGAAGTTTTTTAGGCACCTTTTGAAATGTAATCATTTGGGTCAATATGTAATTTTCAGTGTTAGACTAGTAAATTGTCCGCT AAATTCTGGCCGTTTTTGGCTTTTTTGTTAGACGAAGCTTGGGCCCGGGATCCATTCGATATCAAGCTTATCGATAATCAACCTC TGGATTACAAAATTTGTGAAAGATTGACTGGTATTCTTAACTATGTTGCTCCTTTTACGCTATGTGGATACGCTGCTTTAATGCC TTTGTATCATGCTATTGCTTCCCGTATGGCTTTCATTTTCTCCTCCTTGTATAAATCCTGGTTGCTGTCTCTTTATGAGGAGTTGTG GCCCGTTGTCAGGCAACGTGGCGTGGTGTGCACTGTGTTTGCTGACGCAACCCCCACTGGTTGGGGCATTGCCACCACCTGTC AGCTCCTTTCCGGGACTTTCGCTTTCCCCCTCCCTATTGCCACGGCGGAACTCATCGCCGCCTGCCTTGCCCGCTGCTGGACAGG GGCTCGGCTGTTGGGCACTGACAATTCCGTGGTGTTGTCGGGGAAATCATCGTCCTTTCCTTGGCTGCTCGCCTGTGTTGCCAC CTGGATTCTGCGCGGGACGTCCTTCTGCTACGTCCCTTCGGCCCTCAATCCAGCGGACCTTCCTTCCCGCGGCCTGCTGCCGGC TCTGCGGCCTCTTCCGCGTCTTCGCCTTCGCCCTCAGACGAGTCGGATCTCCCTTTGGGCCGCCTCCCCGCATCGATACCGTCGA CCTCGAGACCTAGAAAAACATGGAGCAATCACAAGTAGCAATACAGCAGCTACCAATGCTGATTGTGCCTGGCTAGAAGCACA AGAGGAGGAGGAGGTGGGTTTTCCAGTCACACCTCAGGTACCTTTAAGACCAATGACTTACAAGGCAGCTGTAGATCTTAGCC ACTTTTTAAAAGAAAAGGGGGGACTGGAAGGGCTAATTCACTCCCAACGAAGACAAGATATCCTTGATCTGTGGATCTACCAC ACACAAGGCTACTTCCCTGATTGGCAGAACTACACACCAGGGCCAGGGATCAGATATCCACTGACCTTTGGATGGTGCTACAA GCTAGTACCAGTTGAGCAAGAGAAGGTAGAAGAAGCCAATGAAGGAGAGAACACCCGCTTGTTACACCCTGTGAGCCTGCAT GGGATGGATGACCCGGAGAGAGAAGTATTAGAGTGGAGGTTTGACAGCCGCCTAGCATTTCATCACATGGCCCGAGAGCTGC ATCCGGACTGTACTGGGTCTCTCTGGTTAGACCAGATCTGAGCCTGGGAGCTCTCTGGCTAACTAGGGAACCCACTGCTTAAG CCTCAATAAAGCTTGCCTTGAGTGCTTCAAGTAGTGTGTGCCCGTCTGTTGTGTGACTCTGGTAACTAGAGATCCCTCAGACCC TTTTAGTCAGTGTGGAAAATCTCTAGCAGGGCCCGTTTAAACCCGCTGATCAGCCTCGACTGTGCCTTCTAGTTGCCAGCCATC TGTTGTTTGCCCCTCCCCCGTGCCTTCCTTGACCCTGGAAGGTGCCACTCCCACTGTCCTTTCCTAATAAAATGAGGAAATTGCA TCGCATTGTCTGAGTAGGTGTCATTCTATTCTGGGGGGTGGGGTGGGGCAGGACAGCAAGGGGGAGGATTGGGAAGACAAT AGCAGGCATGTGAGCAAAAGGCCAGCAAAAGGCCAGGAACCGTAAAAAGGCCGCGTTGCTGGCGTTTTTCCATAGGCTCCGC CCCCCTGACGAGCATCACAAAAATCGACGCTCAAGTCAGAGGTGGCGAAACCCGACAGGACTATAAAGATACCAGGCGTTTC CCCCTGGAAGCTCCCTCGTGCGCTCTCCTGTTCCGACCCTGCCGCTTACCGGATACCTGTCCGCCTTTCTCCCTTCGGGAAGCGT GGCGCTTTCTCATAGCTCACGCTGTAGGTATCTCAGTTCGGTGTAGGTCGTTCGCTCCAAGCTGGGCTGTGTGCACGAACCCCC CGTTCAGCCCGACCGCTGCGCCTTATCCGGTAACTATCGTCTTGAGTCCAACCCGGTAAGACACGACTTATCGCCACTGGCAGC AGCCACTGGTAACAGGATTAGCAGAGCGAGGTATGTAGGCGGTGCTACAGAGTTCTTGAAGTGGTGGCCTAACTACGGCTAC ACTAGAAGAACAGTATTTGGTATCTGCGCTCTGCTGAAGCCAGTTACCTTCGGAAAAAGAGTTGGTAGCTCTTGATCCGGCAA ACAAACCACCGCTGGTAGCGGTGGTTTTTTTGTTTGCAAGCAGCAGATTACGCGCAGAAAAAAAGGATCTCAAGAAGATCCTT TGATCTTTTCTACGGGGTCTGACGCTCAGTGGAACGAAAACTCACGTTAAGGGATTTTGGTCATGAGATTATCAAAAAGGATC TTCACCTAGATCCTTTTAAATTAAAAATGAAGTTTTAAATCAATCTAAAGTATATATGAGTAAACTTGGTCTGACAGTTACCAAT GCTTAATCAGTGAGGCACCTATCTCAGCGATCTGTCTATTTCGTTCATCCATAGTTGCCTGACTCCCCGTCGTGTAGATAACTAC GATACGGGAGGGCTTACCATCTGGCCCCAGTGCTGCAATGATACCGCGAGACCCACGCTCACCGGCTCCAGATTTATCAGCAA TAAACCAGCCAGCCGGAAGGGCCGAGCGCAGAAGTGGTCCTGCAACTTTATCCGCCTCCATCCAGTCTATTAATTGTTGCCGG GAAGCTAGAGTAAGTAGTTCGCCAGTTAATAGTTTGCGCAACGTTGTTGCCATTGCTACAGGCATCGTGGTGTCACGCTCGTC GTTTGGTATGGCTTCATTCAGCTCCGGTTCCCAACGATCAAGGCGAGTTACATGATCCCCCATGTTGTGCAAAAAAGCGGTTAG CTCCTTCGGTCCTCCGATCGTTGTCAGAAGTAAGTTGGCCGCAGTGTTATCACTCATGGTTATGGCAGCACTGCATAATTCTCTT ACTGTCATGCCATCCGTAAGATGCTTTTCTGTGACTGGTGAGTACTCAACCAAGTCATTCTGAGAATAGTGTATGCGGCGACCG AGTTGCTCTTGCCCGGCGTCAATACGGGATAATACCGCGCCACATAGCAGAACTTTAAAAGTGCTCATCATTGGAAAACGTTCT TCGGGGCGAAAACTCTCAAGGATCTTACCGCTGTTGAGATCCAGTTCGATGTAACCCACTCGTGCACCCAACTGATCTTCAGCA TCTTTTACTTTCACCAGCGTTTCTGGGTGAGCAAAAACAGGAAGGCAAAATGCCGCAAAAAAGGGAATAAGGGCGACACGGA AATGTTGAATACTCATACTCTTCCTTTTTCAATATTATTGAAGCATTTATCAGGGTTATTGTCTCATGAGCGGATACATATTTGAA TGTATTTAGAAAAATAAACAAATAGGGGTTCCGCGCACATTTCCCCGAAAAGTGCCACCTGACG SEQIDNo.18-packagingvectorencodingtheGag,Pol,TatandRevgenes TTGATTATTGACTAGTTATTAATAGTAATCAATTACGGGGTCATTAGTTCATAGCCCATATATGGAGTTCCGCGTTACATAACTT ACGGTAAATGGCCCGCCTGGCTGACCGCCCAACGACCCCCGCCCATTGACGTCAATAATGACGTATGTTCCCATAGTAACGCC AATAGGGACTTTCCATTGACGTCAATGGGTGGAGTATTTACGGTAAACTGCCCACTTGGCAGTACATCAAGTGTATCATATGCC AAGTACGCCCCCTATTGACGTCAATGACGGTAAATGGCCCGCCTGGCATTATGCCCAGTACATGACCTTATGGGACTTTCCTAC TTGGCAGTACATCTACGTATTAGTCATCGCTATTACCATGGTCGAGGTGAGCCCCACGTTCTGCTTCACTCTCCCCATCTCCCCC CCCTCCCCACCCCCAATTTTGTATTTATTTATTTTTTAATTATTTTGTGCAGCGATGGGGGCGGGGGGGGGGGGGGGGCGCGC CRGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGSGRGGSGGRGRGGKGCGGCGGCAGCCAATCAGAGCGGCGCG CTCCGAAAGTTTCCTTTTATGGCGAGGCGGCGGCGGCGGCGGCCCTATAAAAAGCGAAGCGCGCGGCGGGGGGAGTCGCT GCGCGCTGCCTTCGCCCCGTGCCCCGCTCCGCCGCCGCCTCGCGCCGCCCGCCCCGGCTCTGACTGACCGCGTTACTCCCACAG GTGAGCGGGCGGGACGGCCCTTCTCCTCCGGGCTGTAATTAGCGCTTGGTTTAATGACGGCTTGTTTCTTTTCTGTGGCTGCGT GAAAGCCTTGAGGGGCTCCGGGAGGGCCCTTTGTGCGGGGGGAGCGGCTCGGGGGGTGCGTGCGTGTGTGTGTGCGTGGG GAGCGCCGCGTGCGGCTCCGCGCTGCCCGGCGGCTGTGAGCGCTGCGGGCGCGGCGCGGGGCTTTGTGCGCTCCGCAGTGT GCGCGAGGGGAGCGCGGCCGGGGGCGGTGCCCCGCGGTGCGGGGGGGGCTGCGAGGGGAACAAAGGCTGCGTGCGGGGT GTGTGCGTGGGGGGGTGAGCAGGGGGTGTGGGCGCGTCGGTCGGGCTGCAACCCCCCCTGCACCCCCCTCCCCGAGTTGCTG AGCACGGCCCGGCTTCGGGTGCGGGGCTCCGTACGGGGCGTGGCGCGGGGCTCGCCGTGCCGGGCGGGGGGTGGCGGCAG GTGGGGGTGCCGGGCGGGGGGGGGCCGCCYCGGGCCGGGGRGGGCTCGGGGGRGGGGCGCGGCGGCCCCCGGAGCGCCG GCGGCTGTCGAGGCGCGGCGAGCCGCAGCCATTGCCTTTTATGGTAATCGTGCGAGAGGGCGCAGGGACTTCCTTTGTCCCA AATCTGTGCGGAGCCGAAATCTGGGAGGCGCCGCCGCACCCCCTCTAGCGGGCGCGGGGCGAAGCGGTGCGGCGCCGGCAG GAAGGAAATGGGGGGGGAGGGCCTTCGTGCGTCGCCGCGCCGCCGTCCCCTTCTCCCTCTCCAGCCTCGGGGCTGTCCGCGG GGGGACGGCTGCCTTCGGGGGGGACGGGGCAGGGGGGGGTTCGGCTTCTGGCGTGTGACCGGCGGCTCTAGAGCCTCTGCT AACCATGTTCATGCCTTCTTCTTTTTCCTACAGCTCCTGGGCAACGTGCTGGTTATTGTGCTGTCTCATCATTTTGGCAAAGAATT CGGGCCGCGTTGACGCGCACGGCAAGAGGCGAGGGGCGGCGACTGGTGAGAGATGGGTGCGAGAGCGTCAGTATTAAGCG GGGGAGAATTAGATCGATGGGAAAAAATTCGGTTAAGGCCAGGGGGAAAGAAAAAATATAAATTAAAACATATAGTATGGG CAAGCAGGGAGCTAGAACGATTCGCAGTTAATCCTGGCCTGTTAGAAACATCAGAAGGCTGTAGACAAATACTGGGACAGCT ACAACCATCCCTTCAGACAGGATCAGAAGAACTTAGATCATTATATAATACAGTAGCAACCCTCTATTGTGTGCATCAAAGGAT AGAGATAAAAGACACCAAGGAAGCTTTAGACAAGATAGAGGAAGAGCAAAACAAAAGTAAGAAAAAAGCACAGCAAGCAGC AGCTGACACAGGACACAGCAATCAGGTCAGCCAAAATTACCCTATAGTGCAGAACATCCAGGGGCAAATGGTACATCAGGCC ATATCACCTAGAACTTTAAATGCATGGGTAAAAGTAGTAGAAGAGAAGGCTTTCAGCCCAGAAGTGATACCCATGTTTTCAGC ATTATCAGAAGGAGCCACCCCACAAGATTTAAACACCATGCTAAACACAGTGGGGGGACATCAAGCAGCCATGCAAATGTTAA AAGAGACCATCAATGAGGAAGCTGCAGAATGGGATAGAGTGCATCCAGTGCATGCAGGGCCTATTGCACCAGGCCAGATGA GAGAACCAAGGGGAAGTGACATAGCAGGAACTACTAGTACCCTTCAGGAACAAATAGGATGGATGACACATAATCCACCTAT CCCAGTAGGAGAAATCTATAAAAGATGGATAATCCTGGGATTAAATAAAATAGTAAGAATGTATAGCCCTACCAGCATTCTGG ACATAAGACAAGGACCAAAGGAACCCTTTAGAGACTATGTAGACCGATTCTATAAAACTCTAAGAGCCGAGCAAGCTTCACAA GAGGTAAAAAATTGGATGACAGAAACCTTGTTGGTCCAAAATGCGAACCCAGATTGTAAGACTATTTTAAAAGCATTGGGACC AGGAGCGACACTAGAAGAAATGATGACAGCATGTCAGGGAGTGGGGGGACCCGGCCATAAAGCAAGAGTTTTGGCTGAAGC AATGAGCCAAGTAACAAATCCAGCTACCATAATGATACAGAAAGGCAATTTTAGGAACCAAAGAAAGACTGTTAAGTGTTTCA ATTGTGGCAAAGAAGGGCACATAGCCAAAAATTGCAGGGCCCCTAGGAAAAAGGGCTGTTGGAAATGTGGAAAGGAAGGAC ACCAAATGAAAGATTGTACTGAGAGACAGGCTAATTTTTTAGGGAAGATCTGGCCTTCCCACAAGGGAAGGCCAGGGAATTTT CTTCAGAGCAGACCAGAGCCAACAGCCCCACCAGAAGAGAGCTTCAGGTTTGGGGAAGAGACAACAACTCCCTCTCAGAAGC AGGAGCCGATAGACAAGGAACTGTATCCTTTAGCTTCCCTCAGATCACTCTTTGGCAGCGACCCCTCGTCACAATAAAGATAGG GGGGCAATTAAAGGAAGCTCTATTAGATACAGGAGCAGATGATACAGTATTAGAAGAAATGAATTTGCCAGGAAGATGGAAA CCAAAAATGATAGGGGGAATTGGAGGTTTTATCAAAGTAAGACAGTATGATCAGATACTCATAGAAATCTGCGGACATAAAG CTATAGGTACAGTATTAGTAGGACCTACACCTGTCAACATAATTGGAAGAAATCTGTTGACTCAGATTGGCTGCACTTTAAATT TTCCCATTAGTCCTATTGAGACTGTACCAGTAAAATTAAAGCCAGGAATGGATGGCCCAAAAGTTAAACAATGGCCATTGACA GAAGAAAAAATAAAAGCATTAGTAGAAATTTGTACAGAAATGGAAAAGGAAGGAAAAATTTCAAAAATTGGGCCTGAAAATC CATACAATACTCCAGTATTTGCCATAAAGAAAAAAGACAGTACTAAATGGAGAAAATTAGTAGATTTCAGAGAACTTAATAAG AGAACTCAAGATTTCTGGGAAGTTCAATTAGGAATACCACATCCTGCAGGGTTAAAACAGAAAAAATCAGTAACAGTACTGGA TGTGGGCGATGCATATTTTTCAGTTCCCTTAGATAAAGACTTCAGGAAGTATACTGCATTTACCATACCTAGTATAAACAATGA GACACCAGGGATTAGATATCAGTACAATGTGCTTCCACAGGGATGGAAAGGATCACCAGCAATATTCCAGTGTAGCATGACAA AAATCTTAGAGCCTTTTAGAAAACAAAATCCAGACATAGTCATCTATCAATACATGGATGATTTGTATGTAGGATCTGACTTAG AAATAGGGCAGCATAGAACAAAAATAGAGGAACTGAGACAACATCTGTTGAGGTGGGGATTTACCACACCAGACAAAAAACA TCAGAAAGAACCTCCATTCCTTTGGATGGGTTATGAACTCCATCCTGATAAATGGACAGTACAGCCTATAGTGCTGCCAGAAAA GGACAGCTGGACTGTCAATGACATACAGAAATTAGTGGGAAAATTGAATTGGGCAAGTCAGATTTATGCAGGGATTAAAGTA AGGCAATTATGTAAACTTCTTAGGGGAACCAAAGCACTAACAGAAGTAGTACCACTAACAGAAGAAGCAGAGCTAGAACTGG CAGAAAACAGGGAGATTCTAAAAGAACCGGTACATGGAGTGTATTATGACCCATCAAAAGACTTAATAGCAGAAATACAGAA GCAGGGGCAAGGCCAATGGACATATCAAATTTATCAAGAGCCATTTAAAAATCTGAAAACAGGAAAGTATGCAAGAATGAAG GGTGCCCACACTAATGATGTGAAACAATTAACAGAGGCAGTACAAAAAATAGCCACAGAAAGCATAGTAATATGGGGAAAGA CTCCTAAATTTAAATTACCCATACAAAAGGAAACATGGGAAGCATGGTGGACAGAGTATTGGCAAGCCACCTGGATTCCTGAG TGGGAGTTTGTCAATACCCCTCCCTTAGTGAAGTTATGGTACCAGTTAGAGAAAGAACCCATAATAGGAGCAGAAACTTTCTAT GTAGATGGGGCAGCCAATAGGGAAACTAAATTAGGAAAAGCAGGATATGTAACTGACAGAGGAAGACAAAAAGTTGTCCCC CTAACGGACACAACAAATCAGAAGACTGAGTTACAAGCAATTCATCTAGCTTTGCAGGATTCGGGATTAGAAGTAAACATAGT GACAGACTCACAATATGCATTGGGAATCATTCAAGCACAACCAGATAAGAGTGAATCAGAGTTAGTCAGTCAAATAATAGAGC AGTTAATAAAAAAGGAAAAAGTCTACCTGGCATGGGTACCAGCACACAAAGGAATTGGAGGAAATGAACAAGTAGATAAATT GGTCAGTGCTGGAATCAGGAAAGTACTATTTTTAGATGGAATAGATAAGGCCCAAGAAGAACATGAGAAATATCACAGTAAT TGGAGAGCAATGGCTAGTGATTTTAACCTACCACCTGTAGTAGCAAAAGAAATAGTAGCCAGCTGTGATAAATGTCAGCTAAA AGGGGAAGCCATGCATGGACAAGTAGACTGTAGCCCAGGAATATGGCAGCTAGATTGTACACATTTAGAAGGAAAAGTTATC TTGGTAGCAGTTCATGTAGCCAGTGGATATATAGAAGCAGAAGTAATTCCAGCAGAGACAGGGCAAGAAACAGCATACTTCC TCTTAAAATTAGCAGGAAGATGGCCAGTAAAAACAGTACATACAGACAATGGCAGCAATTTCACCAGTACTACAGTTAAGGCC GCCTGTTGGTGGGCGGGGATCAAGCAGGAATTTGGCATTCCCTACAATCCCCAAAGTCAAGGAGTAATAGAATCTATGAATAA AGAATTAAAGAAAATTATAGGACAGGTAAGAGATCAGGCTGAACATCTTAAGACAGCAGTACAAATGGCAGTATTCATCCACA ATTTTAAAAGAAAAGGGGGGATTGGGGGGTACAGTGCAGGGGAAAGAATAGTAGACATAATAGCAACAGACATACAAACTA AAGAATTACAAAAACAAATTACAAAAATTCAAAATTTTCGGGTTTATTACAGGGACAGCAGAGATCCAGTTTGGAAAGGACCA GCAAAGCTCCTCTGGAAAGGTGAAGGGGCAGTAGTAATACAAGATAATAGTGACATAAAAGTAGTGCCAAGAAGAAAAGCA AAGATCATCAGGGATTATGGAAAACAGATGGCAGGTGATGATTGTGTGGCAAGTAGACAGGATGAGGATTAACACATGGAA TTCTGCAACAACTGCTGTTTATCCATTTCAGAATTGGGTGTCGACATAGCAGAATAGGCGTTACTCGACAGAGGAGAGCAAGA AATGGAGCCAGTAGATCCTAGACTAGAGCCCTGGAAGCATCCAGGAAGTCAGCCTAAAACTGCTTGTACCAATTGCTATTGTA AAAAGTGTTGCTTTCATTGCCAAGTTTGTTTCATGACAAAAGCCTTAGGCATCTCCTATGGCAGGAAGAAGCGGAGACAGCGA CGAAGAGCTCATCAGAACAGTCAGACTCATCAAGCTTCTCTATCAAAGCAGTAAGTAGTACATGTAATGCAACCTATAATAGTA GCAATAGTAGCATTAGTAGTAGCAATAATAATAGCAATAGTTGTGTGGTCCATAGTAATCATAGAATATAGGAAAATGGCCGC TGATCTTCAGACCTGGAGGAGGAGATATGAGGGACAATTGGAGAAGTGAATTATATAAATATAAAGTAGTAAAAATTGAACC ATTAGGAGTAGCACCCACCAAGGCAAAGAGAAGAGTGGTGCAGAGAGAAAAAAGAGCAGTGGGAATAGGAGCTTTGTTCCT TGGGTTCTTGGGAGCAGCAGGAAGCACTATGGGCGCAGCGTCAATGACGCTGACGGTACAGGCCAGACAATTATTGTCTGGT ATAGTGCAGCAGCAGAACAATTTGCTGAGGGCTATTGAGGCGCAACAGCATCTGTTGCAACTCACAGTCTGGGGCATCAAGC AGCTCCAGGCAAGAATCCTGGCTGTGGAAAGATACCTAAAGGATCAACAGCTCCTGGGGATTTGGGGTTGCTCTGGAAAACT CATTTGCACCACTGCTGTGCCTTGGAATGCTAGTTGGAGTAATAAATCTCTGGAACAGATTTGGAATCACACGACCTGGATGG AGTGGGACAGAGAAATTAACAATTACACAAGCTTAATACACTCCTTAATTGAAGAATCGCAAAACCAGCAAGAAAAGAATGAA CAAGAATTATTGGAATTAGATAAATGGGCAAGTTTGTGGAATTGGTTTAACATAACAAATTGGCTGTGGTATATAAAATTATTC ATAATGATAGTAGGAGGCTTGGTAGGTTTAAGAATAGTTTTTGCTGTACTTTCTATAGTGAATAGAGTTAGGCAGGGATATTC ACCATTATCGTTTCAGACCCACCTCCCAACCCCGAGGGGACCCGACAGGCCCGAAGGAATAGAAGAAGAAGGTGGAGAGAG AGACAGAGACAGATCCATTCGATTAGTGAACGGATCCTTGGCACTTATCTGGGACGATCTGCGGAGCCTGTGCCTCTTCAGCT ACCACCGCTTGAGAGACTTACTCTTGATTGTAACGAGGATTGTGGAACTTCTGGGACGCAGGGGGGGGAAGCCCTCAAATAT TGGTGGAATCTCCTACAATATTGGAGTCAGGAGCTAAAGAATAGTGCTGTTAGCTTGCTCAATGCCACAGCCATAGCAGTAGC TGAGGGGACAGATAGGGTTATAGAAGTAGTACAAGGAGCTTGTAGAGCTATTCGCCACATACCTAGAAGAATAAGACAGGGC TTGGAAAGGATTTTGCTATAAGCTCGAAACAACCGGTACCTCTAGAACTATAGCTAGCAGATCTTTTTCCCTCTGCCAAAAATTA TGGGGACATCATGAAGCCCCTTGAGCATCTGACTTCTGGCTAATAAAGGAAATTTATTTTCATTGCAATAGTGTGTTGGAATTT TTTGTGTCTCTCACTCGGAAGGACATATGGGAGGGCAAATCATTTAAAACATCAGAATGAGTATTTGGTTTAGAGTTTGGCAA CATATGCCCATATGCTGGCTGCCATGAACAAAGGTTGGCTATAAAGAGGTCATCAGTATATGAAACAGCCCCCTGCTGTCCATT CCTTATTCCATAGAAAAGCCTTGACTTGAGGTTAGATTTTTTTTATATTTTGTTTTGTGTTATTTTTTTCTTTAACATCCCTAAAAT TTTCCTTACATGTTTTACTAGCCAGATTTTTCCTCCTCTCCTGACTACTCCCAGTCATAGCTGTCCCTCTTCTCTTATGGAGATCCC TCGACCTGCAGCCCAAGCTTGGCGTAATCATGGTCATAGCTGTTTCCTGTGTGAAATTGTTATCCGCTCACAATTCCACACAACA TACGAGCCGGAAGCATAAAGTGTAAAGCCTGGGGTGCCTAATGAGTGAGCTAACTCACATTAATTGCGTTGCGCTCACTGCCC GCTTTCCAGTCGGGAAACCTGTCGTGCCAGCGGATCCGCATCTCAATTAGTCAGCAACCATAGTCCCGCCCCTAACTCCGCCCA TCCCGCCCCTAACTCCGCCCAGTTCCGCCCATTCTCCGCCCCATGGCTGACTAATTTTTTTTATTTATGCAGAGGCCGAGGCCGC CTCGGCCTCTGAGCTATTCCAGAAGTAGTGAGGAGGCTTTTTTGGAGGCCTAGGCTTTTGCAAAAAGCTAACTTGTTTATTGCA GCTTATAATGGTTACAAATAAAGCAATAGCATCACAAATTTCACAAATAAAGCATTTTTTTCACTGCATTCTAGTTGTGGTTTGT CCAAACTCATCAATGTATCTTATCATGTCTGGATCCGCTGCATTAATGAATCGGCCAACGCGCGGGGAGAGGCGGTTTGCGTA TTGGGCGCTCTTCCGCTTCCTCGCTCACTGACTCGCTGCGCTCGGTCGTTCGGCTGCGGCGAGCGGTATCAGCTCACTCAAAGG CGGTAATACGGTTATCCACAGAATCAGGGGATAACGCAGGAAAGAACATGTGAGCAAAAGGCCAGCAAAAGGCCAGGAACC GTAAAAAGGCCGCGTTGCTGGCGTTTTTCCATAGGCTCCGCCCCCCTGACGAGCATCACAAAAATCGACGCTCAAGTCAGAGG TGGCGAAACCCGACAGGACTATAAAGATACCAGGCGTTTCCCCCTGGAAGCTCCCTCGTGCGCTCTCCTGTTCCGACCCTGCCG CTTACCGGATACCTGTCCGCCTTTCTCCCTTCGGGAAGCGTGGCGCTTTCTCATAGCTCACGCTGTAGGTATCTCAGTTCGGTGT AGGTCGTTCGCTCCAAGCTGGGCTGTGTGCACGAACCCCCCGTTCAGCCCGACCGCTGCGCCTTATCCGGTAACTATCGTCTTG AGTCCAACCCGGTAAGACACGACTTATCGCCACTGGCAGCAGCCACTGGTAACAGGATTAGCAGAGCGAGGTATGTAGGCGG TGCTACAGAGTTCTTGAAGTGGTGGCCTAACTACGGCTACACTAGAAGAACAGTATTTGGTATCTGCGCTCTGCTGAAGCCAG TTACCTTCGGAAAAAGAGTTGGTAGCTCTTGATCCGGCAAACAAACCACCGCTGGTAGCGGTGGTTTTTTTGTTTGCAAGCAGC AGATTACGCGCAGAAAAAAAGGATCTCAAGAAGATCCTTTGATCTTTTCTACGGGGTCTGACGCTCAGTGGAACGAAAACTCA CGTTAAGGGATTTTGGTCATGAGATTATCAAAAAGGATCTTCACCTAGATCCTTTTAAATTAAAAATGAAGTTTTAAATCAATCT AAAGTATATATGAGTAAACTTGGTCTGACAGTTACCAATGCTTAATCAGTGAGGCACCTATCTCAGCGATCTGTCTATTTCGTTC ATCCATAGTTGCCTGACTCCCCGTCGTGTAGATAACTACGATACGGGAGGGCTTACCATCTGGCCCCAGTGCTGCAATGATACC GCGAGACCCACGCTCACCGGCTCCAGATTTATCAGCAATAAACCAGCCAGCCGGAAGGGCCGAGCGCAGAAGTGGTCCTGCA ACTTTATCCGCCTCCATCCAGTCTATTAATTGTTGCCGGGAAGCTAGAGTAAGTAGTTCGCCAGTTAATAGTTTGCGCAACGTT GTTGCCATTGCTACAGGCATCGTGGTGTCACGCTCGTCGTTTGGTATGGCTTCATTCAGCTCCGGTTCCCAACGATCAAGGCGA GTTACATGATCCCCCATGTTGTGCAAAAAAGCGGTTAGCTCCTTCGGTCCTCCGATCGTTGTCAGAAGTAAGTTGGCCGCAGTG TTATCACTCATGGTTATGGCAGCACTGCATAATTCTCTTACTGTCATGCCATCCGTAAGATGCTTTTCTGTGACTGGTGAGTACT CAACCAAGTCATTCTGAGAATAGTGTATGCGGCGACCGAGTTGCTCTTGCCCGGCGTCAATACGGGATAATACCGCGCCACAT AGCAGAACTTTAAAAGTGCTCATCATTGGAAAACGTTCTTCGGGGCGAAAACTCTCAAGGATCTTACCGCTGTTGAGATCCAGT TCGATGTAACCCACTCGTGCACCCAACTGATCTTCAGCATCTTTTACTTTCACCAGCGTTTCTGGGTGAGCAAAAACAGGAAGG CAAAATGCCGCAAAAAAGGGAATAAGGGCGACACGGAAATGTTGAATACTCATACTCTTCCTTTTTCAATATTATTGAAGCATT TATCAGGGTTATTGTCTCATGAGCGGATACATATTTGAATGTATTTAGAAAAATAAACAAATAGGGGTTCCGCGCACATTTCCC CGAAAAGTGCCACCTGGGTCGACA SEQIDNo.19-pMD2.GenvelopevectorencodingtheVSV-Ggene GGATCCCCTGAGGGGGCCCCCATGGGCTAGAGGATCCGGCCTCGGCCTCTGCATAAATAAAAAAAATTAGTCAGCCATGAGC TTGGCCCATTGCATACGTTGTATCCATATCATAATATGTACATTTATATTGGCTCATGTCCAACATTACCGCCATGTTGACATTGA TTATTGACTAGTTATTAATAGTAATCAATTACGGGGTCATTAGTTCATAGCCCATATATGGAGTTCCGCGTTACATAACTTACGG TAAATGGCCCGCCTGGCTGACCGCCCAACGACCCCCGCCCATTGACGTCAATAATGACGTATGTTCCCATAGTAACGCCAATAG GGACTTTCCATTGACGTCAATGGGTGGAGTATTTACGGTAAACTGCCCACTTGGCAGTACATCAAGTGTATCATATGCCAAGTA CGCCCCCTATTGACGTCAATGACGGTAAATGGCCCGCCTGGCATTATGCCCAGTACATGACCTTATGGGACTTTCCTACTTGGC AGTACATCTACGTATTAGTCATCGCTATTACCATGGTGATGCGGTTTTGGCAGTACATCAATGGGCGTGGATAGCGGTTTGACT CACGGGGATTTCCAAGTCTCCACCCCATTGACGTCAATGGGAGTTTGTTTTGGCACCAAAATCAACGGGACTTTCCAAAATGTC GTAACAACTCCGCCCCATTGACGCAAATGGGCGGTAGGCGTGTACGGTGGGAGGTCTATATAAGCAGAGCTCGTTTAGTGAA CCGTCAGATCGCCTGGAGACGCCATCCACGCTGTTTTGACCTCCATAGAAGACACCGGGACCGATCCAGCCTCCCCTCGAAGCT TACATGTGGTACCGAGCTCGGATCCTGAGAACTTCAGGGTGAGTCTATGGGACCCTTGATGTTTTCTTTCCCCTTCTTTTCTATG GTTAAGTTCATGTCATAGGAAGGGGAGAAGTAACAGGGTACACATATTGACCAAATCAGGGTAATTTTGCATTTGTAATTTTA AAAAATGCTTTCTTCTTTTAATATACTTTTTTGTTTATCTTATTTCTAATACTTTCCCTAATCTCTTTCTTTCAGGGCAATAATGATA CAATGTATCATGCCTCTTTGCACCATTCTAAAGAATAACAGTGATAATTTCTGGGTTAAGGCAATAGCAATATTTCTGCATATAA ATATTTCTGCATATAAATTGTAACTGATGTAAGAGGTTTCATATTGCTAATAGCAGCTACAATCCAGCTACCATTCTGCTTTTATT TTATGGTTGGGATAAGGCTGGATTATTCTGAGTCCAAGCTAGGCCCTTTTGCTAATCATGTTCATACCTCTTATCTTCCTCCCAC AGCTCCTGGGCAACGTGCTGGTCTGTGTGCTGGCCCATCACTTTGGCAAAGCACGTGAGATCTGAATTCTGACACTATGAAGT GCCTTTTGTACTTAGCCTTTTTATTCATTGGGGTGAATTGCAAGTTCACCATAGTTTTTCCACACAACCAAAAAGGAAACTGGAA AAATGTTCCTTCTAATTACCATTATTGCCCGTCAAGCTCAGATTTAAATTGGCATAATGACTTAATAGGCACAGCCTTACAAGTC AAAATGCCCAAGAGTCACAAGGCTATTCAAGCAGACGGTTGGATGTGTCATGCTTCCAAATGGGTCACTACTTGTGATTTCCG CTGGTATGGACCGAAGTATATAACACATTCCATCCGATCCTTCACTCCATCTGTAGAACAATGCAAGGAAAGCATTGAACAAAC GAAACAAGGAACTTGGCTGAATCCAGGCTTCCCTCCTCAAAGTTGTGGATATGCAACTGTGACGGATGCCGAAGCAGTGATTG TCCAGGTGACTCCTCACCATGTGCTGGTTGATGAATACACAGGAGAATGGGTTGATTCACAGTTCATCAACGGAAAATGCAGC AATTACATATGCCCCACTGTCCATAACTCTACAACCTGGCATTCTGACTATAAGGTCAAAGGGCTATGTGATTCTAACCTCATTT CCATGGACATCACCTTCTTCTCAGAGGACGGAGAGCTATCATCCCTGGGAAAGGAGGGCACAGGGTTCAGAAGTAACTACTTT GCTTATGAAACTGGAGGCAAGGCCTGCAAAATGCAATACTGCAAGCATTGGGGAGTCAGACTCCCATCAGGTGTCTGGTTCG AGATGGCTGATAAGGATCTCTTTGCTGCAGCCAGATTCCCTGAATGCCCAGAAGGGTCAAGTATCTCTGCTCCATCTCAGACCT CAGTGGATGTAAGTCTAATTCAGGACGTTGAGAGGATCTTGGATTATTCCCTCTGCCAAGAAACCTGGAGCAAAATCAGAGCG GGTCTTCCAATCTCTCCAGTGGATCTCAGCTATCTTGCTCCTAAAAACCCAGGAACCGGTCCTGCTTTCACCATAATCAATGGTA CCCTAAAATACTTTGAGACCAGATACATCAGAGTCGATATTGCTGCTCCAATCCTCTCAAGAATGGTCGGAATGATCAGTGGAA CTACCACAGAAAGGGAACTGTGGGATGACTGGGCACCATATGAAGACGTGGAAATTGGACCCAATGGAGTTCTGAGGACCA GTTCAGGATATAAGTTTCCTTTATACATGATTGGACATGGTATGTTGGACTCCGATCTTCATCTTAGCTCAAAGGCTCAGGTGTT CGAACATCCTCACATTCAAGACGCTGCTTCGCAACTTCCTGATGATGAGAGTTTATTTTTTGGTGATACTGGGCTATCCAAAAAT CCAATCGAGCTTGTAGAAGGTTGGTTCAGTAGTTGGAAAAGCTCTATTGCCTCTTTTTTCTTTATCATAGGGTTAATCATTGGAC TATTCTTGGTTCTCCGAGTTGGTATCCATCTTTGCATTAAATTAAAGCACACCAAGAAAAGACAGATTTATACAGACATAGAGA TGAACCGACTTGGAAAGTAACTCAAATCCTGCACAACAGATTCTTCATGTTTGGACCAAATCAACTTGTGATACCATGCTCAAA GAGGCCTCAATTATATTTGAGTTTTTAATTTTTATGAAAAAAAAAAAAAAAAACGGAATTCACCCCACCAGTGCAGGCTGCCTA TCAGAAAGTGGTGGCTGGTGTGGCTAATGCCCTGGCCCACAAGTATCACTAAGCTCGCTTTCTTGCTGTCCAATTTCTATTAAA GGTTCCTTTGTTCCCTAAGTCCAACTACTAAACTGGGGGATATTATGAAGGGCCTTGAGCATCTGGATTCTGCCTAATAAAAAA CATTTATTTTCATTGCAATGATGTATTTAAATTATTTCTGAATATTTTACTAAAAAGGGAATGTGGGAGGTCAGTGCATTTAAAA CATAAAGAAATGAAGAGCTAGTTCAAACCTTGGGAAAATACACTATATCTTAAACTCCATGAAAGAAGGTGAGGCTGCAAACA GCTAATGCACATTGGCAACAGCCCCTGATGCCTATGCCTTATTCATCCCTCAGAAAAGGATTCAAGTAGAGGCTTGATTTGGAG GTTAAAGTTTTGCTATGCTGTATTTTACATTACTTATTGTTTTAGCTGTCCTCATGAATGTCTTTTCACTACCCATTTGCTTATCCT GCATCTCTCAGCCTTGACTCCACTCAGTTCTCTTGCTTAGAGATACCACCTTTCCCCTGAAGTGTTCCTTCCATGTTTTACGGCGA GATGGTTTCTCCTCGCCTGGCCACTCAGCCTTAGTTGTCTCTGTTGTCTTATAGAGGTCTACTTGAAGAAGGAAAAACAGGGGG CATGGTTTGACTGTCCTGTGAGCCCTTCTTCCCTGCCTCCCCCACTCACAGTGACCCGGAATCCCTCGACATGGCAGTCTAGCAC TAGTGCGGCCGCAGATCTGCTTCCTCGCTCACTGACTCGCTGCGCTCGGTCGTTCGGCTGCGGCGAGCGGTATCAGCTCACTCA AAGGCGGTAATACGGTTATCCACAGAATCAGGGGATAACGCAGGAAAGAACATGTGAGCAAAAGGCCAGCAAAAGGCCAGG AACCGTAAAAAGGCCGCGTTGCTGGCGTTTTTCCATAGGCTCCGCCCCCCTGACGAGCATCACAAAAATCGACGCTCAAGTCA GAGGTGGCGAAACCCGACAGGACTATAAAGATACCAGGCGTTTCCCCCTGGAAGCTCCCTCGTGCGCTCTCCTGTTCCGACCC TGCCGCTTACCGGATACCTGTCCGCCTTTCTCCCTTCGGGAAGCGTGGCGCTTTCTCATAGCTCACGCTGTAGGTATCTCAGTTC GGTGTAGGTCGTTCGCTCCAAGCTGGGCTGTGTGCACGAACCCCCCGTTCAGCCCGACCGCTGCGCCTTATCCGGTAACTATC GTCTTGAGTCCAACCCGGTAAGACACGACTTATCGCCACTGGCAGCAGCCACTGGTAACAGGATTAGCAGAGCGAGGTATGT AGGCGGTGCTACAGAGTTCTTGAAGTGGTGGCCTAACTACGGCTACACTAGAAGAACAGTATTTGGTATCTGCGCTCTGCTGA AGCCAGTTACCTTCGGAAAAAGAGTTGGTAGCTCTTGATCCGGCAAACAAACCACCGCTGGTAGCGGTGGTTTTTTTGTTTGCA AGCAGCAGATTACGCGCAGAAAAAAAGGATCTCAAGAAGATCCTTTGATCTTTTCTACGGGGTCTGACGCTCAGTGGAACGAA AACTCACGTTAAGGGATTTTGGTCATGAGATTATCAAAAAGGATCTTCACCTAGATCCTTTTAAATTAAAAATGAAGTTTTAAAT CAATCTAAAGTATATATGAGTAAACTTGGTCTGACAGTTACCAATGCTTAATCAGTGAGGCACCTATCTCAGCGATCTGTCTATT TCGTTCATCCATAGTTGCCTGACTCCCCGTCGTGTAGATAACTACGATACGGGAGGGCTTACCATCTGGCCCCAGTGCTGCAAT GATACCGCGAGACCCACGCTCACCGGCTCCAGATTTATCAGCAATAAACCAGCCAGCCGGAAGGGCCGAGCGCAGAAGTGGT CCTGCAACTTTATCCGCCTCCATCCAGTCTATTAATTGTTGCCGGGAAGCTAGAGTAAGTAGTTCGCCAGTTAATAGTTTGCGC AACGTTGTTGCCATTGCTACAGGCATCGTGGTGTCACGCTCGTCGTTTGGTATGGCTTCATTCAGCTCCGGTTCCCAACGATCA AGGCGAGTTACATGATCCCCCATGTTGTGCAAAAAAGCGGTTAGCTCCTTCGGTCCTCCGATCGTTGTCAGAAGTAAGTTGGC CGCAGTGTTATCACTCATGGTTATGGCAGCACTGCATAATTCTCTTACTGTCATGCCATCCGTAAGATGCTTTTCTGTGACTGGT GAGTACTCAACCAAGTCATTCTGAGAATAGTGTATGCGGCGACCGAGTTGCTCTTGCCCGGCGTCAATACGGGATAATACCGC GCCACATAGCAGAACTTTAAAAGTGCTCATCATTGGAAAACGTTCTTCGGGGCGAAAACTCTCAAGGATCTTACCGCTGTTGA GATCCAGTTCGATGTAACCCACTCGTGCACCCAACTGATCTTCAGCATCTTTTACTTTCACCAGCGTTTCTGGGTGAGCAAAAAC AGGAAGGCAAAATGCCGCAAAAAAGGGAATAAGGGCGACACGGAAATGTTGAATACTCATACTCTTCCTTTTTCAATATTATT GAAGCATTTATCAGGGTTATTGTCTCATGAGCGGATACATATTTGAATGTATTTAGAAAAATAAACAAATAGGGGTTCCGCGC ACATTTCCCCGAAAAGTGCCACCTGACGT SEQIDNo.20-FUW-GaGiFo(vector1) TCGACGGATCGGGAGATCTCCCGATCCCCTATGGTGCACTCTCAGTACAATCTGCTCTGATGCCGCATAGTTAAGCCAGTATCT GCTCCCTGCTTGTGTGTTGGAGGTCGCTGAGTAGTGCGCGAGCAAAATTTAAGCTACAACAAGGCAAGGCTTGACCGACAATT GCATGAAGAATCTGCTTAGGGTTAGGCGTTTTGCGCTGCTTCGCGATGTACGGGCCAGATATACGCGTTGACATTGATTATTG ACTAGTTATTAATAGTAATCAATTACGGGGTCATTAGTTCATAGCCCATATATGGAGTTCCGCGTTACATAACTTACGGTAAAT GGCCCGCCTGGCTGACCGCCCAACGACCCCCGCCCATTGACGTCAATAATGACGTATGTTCCCATAGTAACGCCAATAGGGAC TTTCCATTGACGTCAATGGGTGGAGTATTTACGGTAAACTGCCCACTTGGCAGTACATCAAGTGTATCATATGCCAAGTACGCC CCCTATTGACGTCAATGACGGTAAATGGCCCGCCTGGCATTATGCCCAGTACATGACCTTATGGGACTTTCCTACTTGGCAGTA CATCTACGTATTAGTCATCGCTATTACCATGGTGATGCGGTTTTGGCAGTACATCAATGGGCGTGGATAGCGGTTTGACTCACG GGGATTTCCAAGTCTCCACCCCATTGACGTCAATGGGAGTTTGTTTTGGCACCAAAATCAACGGGACTTTCCAAAATGTCGTAA CAACTCCGCCCCATTGACGCAAATGGGCGGTAGGCGTGTACGGTGGGAGGTCTATATAAGCAGCGCGTTTTGCCTGTACTGG GTCTCTCTGGTTAGACCAGATCTGAGCCTGGGAGCTCTCTGGCTAACTAGGGAACCCACTGCTTAAGCCTCAATAAAGCTTGCC TTGAGTGCTTCAAGTAGTGTGTGCCCGTCTGTTGTGTGACTCTGGTAACTAGAGATCCCTCAGACCCTTTTAGTCAGTGTGGAA AATCTCTAGCAGTGGCGCCCGAACAGGGACTTGAAAGCGAAAGGGAAACCAGAGGAGCTCTCTCGACGCAGGACTCGGCTTG CTGAAGCGCGCACGGCAAGAGGCGAGGGGCGGCGACTGGTGAGTACGCCAAAAATTTTGACTAGCGGAGGCTAGAAGGAG AGAGATGGGTGCGAGAGCGTCAGTATTAAGCGGGGGAGAATTAGATCGCGATGGGAAAAAATTCGGTTAAGGCCAGGGGG AAAGAAAAAATATAAATTAAAACATATAGTATGGGCAAGCAGGGAGCTAGAACGATTCGCAGTTAATCCTGGCCTGTTAGAA ACATCAGAAGGCTGTAGACAAATACTGGGACAGCTACAACCATCCCTTCAGACAGGATCAGAAGAACTTAGATCATTATATAA TACAGTAGCAACCCTCTATTGTGTGCATCAAAGGATAGAGATAAAAGACACCAAGGAAGCTTTAGACAAGATAGAGGAAGAG CAAAACAAAAGTAAGACCACCGCACAGCAAGCGGCCGCTGATCTTCAGACCTGGAGGAGGAGATATGAGGGACAATTGGAG AAGTGAATTATATAAATATAAAGTAGTAAAAATTGAACCATTAGGAGTAGCACCCACCAAGGCAAAGAGAAGAGTGGTGCAG AGAGAAAAAAGAGCAGTGGGAATAGGAGCTTTGTTCCTTGGGTTCTTGGGAGCAGCAGGAAGCACTATGGGCGCAGCGTCA ATGACGCTGACGGTACAGGCCAGACAATTATTGTCTGGTATAGTGCAGCAGCAGAACAATTTGCTGAGGGCTATTGAGGCGC AACAGCATCTGTTGCAACTCACAGTCTGGGGCATCAAGCAGCTCCAGGCAAGAATCCTGGCTGTGGAAAGATACCTAAAGGAT CAACAGCTCCTGGGGATTTGGGGTTGCTCTGGAAAACTCATTTGCACCACTGCTGTGCCTTGGAATGCTAGTTGGAGTAATAA ATCTCTGGAACAGATTTGGAATCACACGACCTGGATGGAGTGGGACAGAGAAATTAACAATTACACAAGCTTAATACACTCCT TAATTGAAGAATCGCAAAACCAGCAAGAAAAGAATGAACAAGAATTATTGGAATTAGATAAATGGGCAAGTTTGTGGAATTG GTTTAACATAACAAATTGGCTGTGGTATATAAAATTATTCATAATGATAGTAGGAGGCTTGGTAGGTTTAAGAATAGTTTTTGC TGTACTTTCTATAGTGAATAGAGTTAGGCAGGGATATTCACCATTATCGTTTCAGACCCACCTCCCAACCCCGAGGGGACCCGA CAGGCCCGAAGGAATAGAAGAAGAAGGTGGAGAGAGAGACAGAGACAGATCCATTCGATTAGTGAACGGATCGGCACTGC GTGCGCCAATTCTGCAGACAAATGGCAGTATTCATCCACAATTTTAAAAGAAAAGGGGGGATTGGGGGGTACAGTGCAGGGG AAAGAATAGTAGACATAATAGCAACAGACATACAAACTAAAGAATTACAAAAACAAATTACAAAAATTCAAAATTTTCGGGTT TATTACAGGGACAGCAGAGATCCAGTTTGGTTAATTAACCCGTGTCGGCTCCAGATCTGGCCTCCGCGCCGGGTTTTGGCGCC TCCCGCGGGCGCCCCCCTCCTCACGGCGAGCGCTGCCACGTCAGACGAAGGGCGCAGCGAGCGTCCTGATCCTTCCGCCCGG ACGCTCAGGACAGCGGCCCGCTGCTCATAAGACTCGGCCTTAGAACCCCAGTATCAGCAGAAGGACATTTTAGGACGGGACTT GGGTGACTCTAGGGCACTGGTTTTCTTTCCAGAGAGCGGAACAGGCGAGGAAAAGTAGTCCCTTCTCGGCGATTCTGCGGAG GGATCTCCGTGGGGCGGTGAACGCCGATGATTATATAAGGACGCGCCGGGTGTGGCACAGCTAGTTCCGTCGCAGCCGGGAT TTGGGTCGCGGTTCTTGTTTGTGGATCGCTGTGATCGTCACTTGGTGAGTAGCGGGCTGCTGGGCTGGCCGGGGCTTTCGTGG CCGCCGGGCCGCTCGGTGGGACGGAAGCGTGTGGAGAGACCGCCAAGGGCTGTAGTCTGGGTCCGCGAGCAAGGTTGCCCT GAACTGGGGGTTGGGGGGAGCGCAGCAAAATGGCGGCTGTTCCCGAGTCTTGAATGGAAGACGCTTGTGAGGCGGGCTGTG AGGTCGTTGAAACAAGGTGGGGGGCATGGTGGGCGGCAAGAACCCAAGGTCTTGAGGCCTTCGCTAATGCGGGAAAGCTCT TATTCGGGTGAGATGGGCTGGGGCACCATCTGGGGACCCTGACGTGAAGTTTGTCACTGACTGGAGAACTCGGTTTGTCGTCT GTTGCGGGGGCGGCAGTTATGGCGGTGCCGTTGGGCAGTGCACCCGTACCTTTGGGAGCGCGCGCCCTCGTCGTGTCGTGAC GTCACCCGTTCTGTTGGCTTATAATGCAGGGTGGGGCCACCTGCCGGTAGGTGTGCGGTAGGCTTTTCTCCGTCGCAGGACGC AGGGTTCGGGCCTAGGGTAGGCTCTCCTGAATCGACAGGCGCCGGACCTCTGGTGAGGGGAGGGATAAGTGAGGCGTCAGT TTCTTTGGTCGGTTTTATGTACCTATCTTCTTAAGTAGCTGAAGCTCCGGTTTTGAACTATGCGCTCGGGGTTGGCGAGTGTGTT TTGTGAAGTTTTTTAGGCACCTTTTGAAATGTAATCATTTGGGTCAATATGTAATTTTCAGTGTTAGACTAGTAAATTGTCCGCT AAATTCTGGCCGTTTTTGGCTTTTTTGTTAGACGAAGCTTGGGCCCGGGATCCATGGAAGTCGCTCCTGAACAACCACGGTGG ATGGCTCATCCTGCAGTTCTTAACGCTCAACATCCAGATAGCCATCATCCTGGGCTCGCTCATAATTATATGGAGCCTGCCCAAC TCCTTCCCCCAGATGAAGTAGATGTATTCTTTAACCATCTTGATAGCCAAGGAAATCCTTATTACGCAAATCCTGCCCATGCCAG AGCCAGAGTAAGCTATTCACCAGCCCATGCAAGGCTTACTGGTGGACAAATGTGTCGGCCCCATCTGCTGCATTCCCCCGGCCT GCCGTGGTTGGATGGCGGAAAGGCGGCTCTGAGTGCGGCGGCTGCACATCATCATAATCCTTGGACAGTCTCACCTTTCTCTA AAACTCCCCTTCATCCTAGTGCAGCCGGTGGTCCAGGTGGTCCGCTGTCCGTTTATCCCGGCGCCGGCGGCGGAAGTGGCGGC GGAAGTGGCAGTAGCGTAGCTTCATTGACACCCACAGCTGCTCATTCCGGAAGTCATCTCTTTGGGTTTCCCCCTACCCCGCCG AAAGAGGTTTCCCCAGATCCGTCAACTACCGGTGCCGCTTCCCCTGCTAGTTCCAGTGCCGGCGGAAGCGCTGCAAGGGGCGA AGATAAAGATGGAGTGAAATATCAAGTCTCCTTGACAGAATCCATGAAAATGGAGTCCGGTTCTCCACTCAGGCCTGGACTCG CCACAATGGGTACTCAACCCGCCACCCATCATCCAATACCGACTTATCCTTCATACGTACCAGCCGCCGCTCATGATTATTCATC AGGTTTGTTTCATCCAGGTGGATTTCTTGGCGGGCCTGCTAGTTCTTTTACACCAAAACAAAGGTCCAAAGCCAGGTCTTGCAG TGAGGGGCGCGAATGCGTAAATTGCGGCGCTACCGCAACACCACTGTGGCGTCGTGATGGAACAGGACATTATCTTTGTAAC GCATGCGGGCTGTATCATAAAATGAACGGACAAAATCGGCCCCTGATTAAACCTAAACGTCGCTTGTCTGCTGCAAGGCGGGC TGGGACGTGCTGCGCCAACTGCCAAACAACCACAACAACACTGTGGCGTAGGAATGCTAATGGCGATCCCGTATGTAATGCAT GCGGTCTGTATTATAAACTTCATAACGTCAATCGGCCCCTTACTATGAAGAAAGAGGGCATACAAACCCGAAATCGCAAAATG TCAAATAAATCTAAGAAATCCAAGAAGGGAGCCGAATGTTTTGAAGAACTCAGCAAATGTATGCAAGAAAAGTCCAGCCCGTT TTCCGCCGCCGCTTTGGCCGGCCATATGGCCCCCGTCGGACATCTGCCACCGTTTTCCCATAGCGGTCATATTCTTCCTACACCC ACCCCAATTCATCCGTCTAGCTCCCTGTCTTTTGGGCATCCTCATCCTAGCTCAATGGTCACAGCTATGGGTGGCAGCGGCGCC ACAAACTTCTCTCTGCTAAAGCAAGCAGGTGATGTTGAAGAAAACCCCGGGCCTATGCCGAGGAGCTTTCTCGTTAAATCCAA GAAAGCGCATACATATCATCAACCTAGGGTCCAAGAGGACGAGCCACTGTGGCCACCCGCTCTCACACCAGTTCCTCGGGATC AAGCACCTTCTAATTCACCCGTGTTGAGTACCTTGTTTCCGAATCAATGTCTCGATTGGACTAATCTGAAGCGGGAACCAGAAT TGGAACAAGATCAAAATCTGGCACGCATGGCTCCCGCTCCTGAAGGTCCAATCGTTCTCAGTCGGCCGCAAGACGGCGATTCC CCGCTTTCTGATAGCCCACCGTTTTATAAACCATCTTTTAGCTGGGATACGCTCGCTACGACATACGGTCATTCCTATAGACAAG CTCCGTCAACTATGCAAAGCGCTTTTCTCGAACATAGCGTTTCACTTTATGGATCACCCCTCGTCCCTTCCACCGAACCTGCTCTG GACTTTTCCCTGAGATATTCTCCCGGGATGGACGCCTATCATTGCGTTAAATGTAATAAAGTGTTTTCAACACCGCATGGTCTTG AGGTCCACGTACGCCGATCACACAGCGGCACTCGCCCGTTTGCATGCGATATTTGTGGAAAGACTTTTGGACATGCCGTCTCTC TCGAACAACATACACATGTGCATTCACAAGAACGTTCCTTTGAATGTCGAATGTGTGGGAAAGCGTTTAAAAGGTCAAGTACC CTCAGCACGCATCTTCTTATTCATTCTGATACCCGCCCTTATCCATGTCAATTTTGTGGGAAACGCTTTCATCAGAAAAGTGATA TGAAGAAACATACGTATATTCATACCGGGGAAAAGCCACATAAATGTCAAGTATGTGGCAAAGCATTTTCCCAAAGTTCTAATT TGATAACGCATAGTCGAAAACATACTGGGTTTAAACCATTTTCCTGCGAACTCTGTACTAAGGGATTTCAAAGGAAAGTAGATC TTAGAAGGCATAGGGAATCCCAACATAACCTGAAAGGCTCCGGCGAGGGCAGGGGAAGTCTTCTAACATGCGGGGACGTGG AGGAAAATCCCGGCCCAATGATGTTTTCCGGGTTTAATGCCGATTATGAAGCATCCAGTTCTAGGTGTAGTTCTGCAAGTCCCG CGGGCGACTCACTGTCATATTATCATAGCCCGGCTGATAGCTTTTCTTCTATGGGGTCACCCGTGAATGCCCAAGATTTCTGTAC TGATTTGGCAGTGAGCTCAGCTAATTTTATCCCTACTGTGACCGCTATAAGCACTTCTCCTGATCTCCAATGGCTCGTCCAACCA GCACTGGTTAGTTCAGTCGCTCCCAGTCAAACACGGGCACCCCATCCGTTTGGGGTTCCAGCACCTTCAGCAGGCGCCTATAGC CGGGCCGGAGTCGTAAAGACAATGACTGGTGGGAGAGCCCAATCAATCGGAAGAAGAGGAAAAGTCGAGCAACTTAGCCCT GAGGAAGAGGAAAAGAGACGCATTAGGCGCGAGCGGAACAAAATGGCCGCCGCTAAGTGTCGAAATAGGCGTCGTGAACTC ACAGACACCCTGCAGGCCGAAACCGATCAGCTTGAGGACGAGAAAAGTGCACTGCAAACTGAAATCGCTAATCTTCTCAAAG AGAAAGAGAAGCTGGAATTTATTCTCGCTGCACATCGTCCAGCATGTAAAATTCCCGACGATCTCGGATTTCCGGAAGAAATG AGCGTAGCCAGTCTCGACCTTACCGGTGGACTCCCTGAAGTCGCGACACCTGAATCCGAAGAAGCGTTTACATTGCCCTTGCT GAACGATCCGGAACCAAAACCAAGCGTCGAGCCCGTGAAAAGTATATCATCTATGGAACTTAAAACTGAACCTTTCGACGATT TTCTCTTTCCTGCTTCCAGCCGCCCATCAGGGTCAGAAACCGCTAGATCTGTCCCCGATATGGATCTGAGCGGAAGCTTTTACG CTGCCGATTGGGAACCACTCCATTCAGGTAGTCTTGGCATGGGCCCTATGGCGACCGAACTTGAACCTCTTTGTACACCCGTTG TAACTTGCACCCCATCCTGTACGGCCTATACCTCAAGTTTTGTATTTACATATCCTGAAGCCGATTCTTTTCCATCCTGCGCCGCC GCGCATCGAAAAGGGTCTTCATCTAACGAACCATCTTCCGATAGTTTGAGTAGTCCAACCCTTCTTGCTCTCTAAGGATCCATTC GATATCAAGCTTATCGATAATCAACCTCTGGATTACAAAATTTGTGAAAGATTGACTGGTATTCTTAACTATGTTGCTCCTTTTA CGCTATGTGGATACGCTGCTTTAATGCCTTTGTATCATGCTATTGCTTCCCGTATGGCTTTCATTTTCTCCTCCTTGTATAAATCCT GGTTGCTGTCTCTTTATGAGGAGTTGTGGCCCGTTGTCAGGCAACGTGGCGTGGTGTGCACTGTGTTTGCTGACGCAACCCCC ACTGGTTGGGGCATTGCCACCACCTGTCAGCTCCTTTCCGGGACTTTCGCTTTCCCCCTCCCTATTGCCACGGCGGAACTCATCG CCGCCTGCCTTGCCCGCTGCTGGACAGGGGCTCGGCTGTTGGGCACTGACAATTCCGTGGTGTTGTCGGGGAAATCATCGTCC TTTCCTTGGCTGCTCGCCTGTGTTGCCACCTGGATTCTGCGCGGGACGTCCTTCTGCTACGTCCCTTCGGCCCTCAATCCAGCGG ACCTTCCTTCCCGCGGCCTGCTGCCGGCTCTGCGGCCTCTTCCGCGTCTTCGCCTTCGCCCTCAGACGAGTCGGATCTCCCTTTG GGCCGCCTCCCCGCATCGATACCGTCGACCTCGAGACCTAGAAAAACATGGAGCAATCACAAGTAGCAATACAGCAGCTACCA ATGCTGATTGTGCCTGGCTAGAAGCACAAGAGGAGGAGGAGGTGGGTTTTCCAGTCACACCTCAGGTACCTTTAAGACCAAT GACTTACAAGGCAGCTGTAGATCTTAGCCACTTTTTAAAAGAAAAGGGGGGACTGGAAGGGCTAATTCACTCCCAACGAAGA CAAGATATCCTTGATCTGTGGATCTACCACACACAAGGCTACTTCCCTGATTGGCAGAACTACACACCAGGGCCAGGGATCAG ATATCCACTGACCTTTGGATGGTGCTACAAGCTAGTACCAGTTGAGCAAGAGAAGGTAGAAGAAGCCAATGAAGGAGAGAAC ACCCGCTTGTTACACCCTGTGAGCCTGCATGGGATGGATGACCCGGAGAGAGAAGTATTAGAGTGGAGGTTTGACAGCCGCC TAGCATTTCATCACATGGCCCGAGAGCTGCATCCGGACTGTACTGGGTCTCTCTGGTTAGACCAGATCTGAGCCTGGGAGCTCT CTGGCTAACTAGGGAACCCACTGCTTAAGCCTCAATAAAGCTTGCCTTGAGTGCTTCAAGTAGTGTGTGCCCGTCTGTTGTGTG ACTCTGGTAACTAGAGATCCCTCAGACCCTTTTAGTCAGTGTGGAAAATCTCTAGCAGGGCCCGTTTAAACCCGCTGATCAGCC TCGACTGTGCCTTCTAGTTGCCAGCCATCTGTTGTTTGCCCCTCCCCCGTGCCTTCCTTGACCCTGGAAGGTGCCACTCCCACTG TCCTTTCCTAATAAAATGAGGAAATTGCATCGCATTGTCTGAGTAGGTGTCATTCTATTCTGGGGGGTGGGGTGGGGCAGGAC AGCAAGGGGGAGGATTGGGAAGACAATAGCAGGCATGTGAGCAAAAGGCCAGCAAAAGGCCAGGAACCGTAAAAAGGCCG CGTTGCTGGCGTTTTTCCATAGGCTCCGCCCCCCTGACGAGCATCACAAAAATCGACGCTCAAGTCAGAGGTGGCGAAACCCG ACAGGACTATAAAGATACCAGGCGTTTCCCCCTGGAAGCTCCCTCGTGCGCTCTCCTGTTCCGACCCTGCCGCTTACCGGATAC CTGTCCGCCTTTCTCCCTTCGGGAAGCGTGGCGCTTTCTCATAGCTCACGCTGTAGGTATCTCAGTTCGGTGTAGGTCGTTCGCT CCAAGCTGGGCTGTGTGCACGAACCCCCCGTTCAGCCCGACCGCTGCGCCTTATCCGGTAACTATCGTCTTGAGTCCAACCCGG TAAGACACGACTTATCGCCACTGGCAGCAGCCACTGGTAACAGGATTAGCAGAGCGAGGTATGTAGGCGGTGCTACAGAGTT CTTGAAGTGGTGGCCTAACTACGGCTACACTAGAAGAACAGTATTTGGTATCTGCGCTCTGCTGAAGCCAGTTACCTTCGGAA AAAGAGTTGGTAGCTCTTGATCCGGCAAACAAACCACCGCTGGTAGCGGTGGTTTTTTTGTTTGCAAGCAGCAGATTACGCGC AGAAAAAAAGGATCTCAAGAAGATCCTTTGATCTTTTCTACGGGGTCTGACGCTCAGTGGAACGAAAACTCACGTTAAGGGAT TTTGGTCATGAGATTATCAAAAAGGATCTTCACCTAGATCCTTTTAAATTAAAAATGAAGTTTTAAATCAATCTAAAGTATATAT GAGTAAACTTGGTCTGACAGTTACCAATGCTTAATCAGTGAGGCACCTATCTCAGCGATCTGTCTATTTCGTTCATCCATAGTTG CCTGACTCCCCGTCGTGTAGATAACTACGATACGGGAGGGCTTACCATCTGGCCCCAGTGCTGCAATGATACCGCGAGACCCA CGCTCACCGGCTCCAGATTTATCAGCAATAAACCAGCCAGCCGGAAGGGCCGAGCGCAGAAGTGGTCCTGCAACTTTATCCGC CTCCATCCAGTCTATTAATTGTTGCCGGGAAGCTAGAGTAAGTAGTTCGCCAGTTAATAGTTTGCGCAACGTTGTTGCCATTGC TACAGGCATCGTGGTGTCACGCTCGTCGTTTGGTATGGCTTCATTCAGCTCCGGTTCCCAACGATCAAGGCGAGTTACATGATC CCCCATGTTGTGCAAAAAAGCGGTTAGCTCCTTCGGTCCTCCGATCGTTGTCAGAAGTAAGTTGGCCGCAGTGTTATCACTCAT GGTTATGGCAGCACTGCATAATTCTCTTACTGTCATGCCATCCGTAAGATGCTTTTCTGTGACTGGTGAGTACTCAACCAAGTCA TTCTGAGAATAGTGTATGCGGCGACCGAGTTGCTCTTGCCCGGCGTCAATACGGGATAATACCGCGCCACATAGCAGAACTTT AAAAGTGCTCATCATTGGAAAACGTTCTTCGGGGCGAAAACTCTCAAGGATCTTACCGCTGTTGAGATCCAGTTCGATGTAACC CACTCGTGCACCCAACTGATCTTCAGCATCTTTTACTTTCACCAGCGTTTCTGGGTGAGCAAAAACAGGAAGGCAAAATGCCGC AAAAAAGGGAATAAGGGCGACACGGAAATGTTGAATACTCATACTCTTCCTTTTTCAATATTATTGAAGCATTTATCAGGGTTA TTGTCTCATGAGCGGATACATATTTGAATGTATTTAGAAAAATAAACAAATAGGGGTTCCGCGCACATTTCCCCGAAAAGTGCC ACCTGACG SEQIDNo.21-FUW-GaFoGi(vector2) TCGACGGATCGGGAGATCTCCCGATCCCCTATGGTGCACTCTCAGTACAATCTGCTCTGATGCCGCATAGTTAAGCCAGTATCT GCTCCCTGCTTGTGTGTTGGAGGTCGCTGAGTAGTGCGCGAGCAAAATTTAAGCTACAACAAGGCAAGGCTTGACCGACAATT GCATGAAGAATCTGCTTAGGGTTAGGCGTTTTGCGCTGCTTCGCGATGTACGGGCCAGATATACGCGTTGACATTGATTATTG ACTAGTTATTAATAGTAATCAATTACGGGGTCATTAGTTCATAGCCCATATATGGAGTTCCGCGTTACATAACTTACGGTAAAT GGCCCGCCTGGCTGACCGCCCAACGACCCCCGCCCATTGACGTCAATAATGACGTATGTTCCCATAGTAACGCCAATAGGGAC TTTCCATTGACGTCAATGGGTGGAGTATTTACGGTAAACTGCCCACTTGGCAGTACATCAAGTGTATCATATGCCAAGTACGCC CCCTATTGACGTCAATGACGGTAAATGGCCCGCCTGGCATTATGCCCAGTACATGACCTTATGGGACTTTCCTACTTGGCAGTA CATCTACGTATTAGTCATCGCTATTACCATGGTGATGCGGTTTTGGCAGTACATCAATGGGCGTGGATAGCGGTTTGACTCACG GGGATTTCCAAGTCTCCACCCCATTGACGTCAATGGGAGTTTGTTTTGGCACCAAAATCAACGGGACTTTCCAAAATGTCGTAA CAACTCCGCCCCATTGACGCAAATGGGCGGTAGGCGTGTACGGTGGGAGGTCTATATAAGCAGCGCGTTTTGCCTGTACTGG GTCTCTCTGGTTAGACCAGATCTGAGCCTGGGAGCTCTCTGGCTAACTAGGGAACCCACTGCTTAAGCCTCAATAAAGCTTGCC TTGAGTGCTTCAAGTAGTGTGTGCCCGTCTGTTGTGTGACTCTGGTAACTAGAGATCCCTCAGACCCTTTTAGTCAGTGTGGAA AATCTCTAGCAGTGGCGCCCGAACAGGGACTTGAAAGCGAAAGGGAAACCAGAGGAGCTCTCTCGACGCAGGACTCGGCTTG CTGAAGCGCGCACGGCAAGAGGCGAGGGGCGGCGACTGGTGAGTACGCCAAAAATTTTGACTAGCGGAGGCTAGAAGGAG AGAGATGGGTGCGAGAGCGTCAGTATTAAGCGGGGGAGAATTAGATCGCGATGGGAAAAAATTCGGTTAAGGCCAGGGGG AAAGAAAAAATATAAATTAAAACATATAGTATGGGCAAGCAGGGAGCTAGAACGATTCGCAGTTAATCCTGGCCTGTTAGAA ACATCAGAAGGCTGTAGACAAATACTGGGACAGCTACAACCATCCCTTCAGACAGGATCAGAAGAACTTAGATCATTATATAA TACAGTAGCAACCCTCTATTGTGTGCATCAAAGGATAGAGATAAAAGACACCAAGGAAGCTTTAGACAAGATAGAGGAAGAG CAAAACAAAAGTAAGACCACCGCACAGCAAGCGGCCGCTGATCTTCAGACCTGGAGGAGGAGATATGAGGGACAATTGGAG AAGTGAATTATATAAATATAAAGTAGTAAAAATTGAACCATTAGGAGTAGCACCCACCAAGGCAAAGAGAAGAGTGGTGCAG AGAGAAAAAAGAGCAGTGGGAATAGGAGCTTTGTTCCTTGGGTTCTTGGGAGCAGCAGGAAGCACTATGGGCGCAGCGTCA ATGACGCTGACGGTACAGGCCAGACAATTATTGTCTGGTATAGTGCAGCAGCAGAACAATTTGCTGAGGGCTATTGAGGCGC AACAGCATCTGTTGCAACTCACAGTCTGGGGCATCAAGCAGCTCCAGGCAAGAATCCTGGCTGTGGAAAGATACCTAAAGGAT CAACAGCTCCTGGGGATTTGGGGTTGCTCTGGAAAACTCATTTGCACCACTGCTGTGCCTTGGAATGCTAGTTGGAGTAATAA ATCTCTGGAACAGATTTGGAATCACACGACCTGGATGGAGTGGGACAGAGAAATTAACAATTACACAAGCTTAATACACTCCT TAATTGAAGAATCGCAAAACCAGCAAGAAAAGAATGAACAAGAATTATTGGAATTAGATAAATGGGCAAGTTTGTGGAATTG GTTTAACATAACAAATTGGCTGTGGTATATAAAATTATTCATAATGATAGTAGGAGGCTTGGTAGGTTTAAGAATAGTTTTTGC TGTACTTTCTATAGTGAATAGAGTTAGGCAGGGATATTCACCATTATCGTTTCAGACCCACCTCCCAACCCCGAGGGGACCCGA CAGGCCCGAAGGAATAGAAGAAGAAGGTGGAGAGAGAGACAGAGACAGATCCATTCGATTAGTGAACGGATCGGCACTGC GTGCGCCAATTCTGCAGACAAATGGCAGTATTCATCCACAATTTTAAAAGAAAAGGGGGGATTGGGGGGTACAGTGCAGGGG AAAGAATAGTAGACATAATAGCAACAGACATACAAACTAAAGAATTACAAAAACAAATTACAAAAATTCAAAATTTTCGGGTT TATTACAGGGACAGCAGAGATCCAGTTTGGTTAATTAACCCGTGTCGGCTCCAGATCTGGCCTCCGCGCCGGGTTTTGGCGCC TCCCGCGGGCGCCCCCCTCCTCACGGCGAGCGCTGCCACGTCAGACGAAGGGCGCAGCGAGCGTCCTGATCCTTCCGCCCGG ACGCTCAGGACAGCGGCCCGCTGCTCATAAGACTCGGCCTTAGAACCCCAGTATCAGCAGAAGGACATTTTAGGACGGGACTT GGGTGACTCTAGGGCACTGGTTTTCTTTCCAGAGAGCGGAACAGGCGAGGAAAAGTAGTCCCTTCTCGGCGATTCTGCGGAG GGATCTCCGTGGGGCGGTGAACGCCGATGATTATATAAGGACGCGCCGGGTGTGGCACAGCTAGTTCCGTCGCAGCCGGGAT TTGGGTCGCGGTTCTTGTTTGTGGATCGCTGTGATCGTCACTTGGTGAGTAGCGGGCTGCTGGGCTGGCCGGGGCTTTCGTGG CCGCCGGGCCGCTCGGTGGGACGGAAGCGTGTGGAGAGACCGCCAAGGGCTGTAGTCTGGGTCCGCGAGCAAGGTTGCCCT GAACTGGGGGTTGGGGGGAGCGCAGCAAAATGGCGGCTGTTCCCGAGTCTTGAATGGAAGACGCTTGTGAGGCGGGCTGTG AGGTCGTTGAAACAAGGTGGGGGGCATGGTGGGCGGCAAGAACCCAAGGTCTTGAGGCCTTCGCTAATGCGGGAAAGCTCT TATTCGGGTGAGATGGGCTGGGGCACCATCTGGGGACCCTGACGTGAAGTTTGTCACTGACTGGAGAACTCGGTTTGTCGTCT GTTGCGGGGGCGGCAGTTATGGCGGTGCCGTTGGGCAGTGCACCCGTACCTTTGGGAGCGCGCGCCCTCGTCGTGTCGTGAC GTCACCCGTTCTGTTGGCTTATAATGCAGGGTGGGGCCACCTGCCGGTAGGTGTGCGGTAGGCTTTTCTCCGTCGCAGGACGC AGGGTTCGGGCCTAGGGTAGGCTCTCCTGAATCGACAGGCGCCGGACCTCTGGTGAGGGGAGGGATAAGTGAGGCGTCAGT TTCTTTGGTCGGTTTTATGTACCTATCTTCTTAAGTAGCTGAAGCTCCGGTTTTGAACTATGCGCTCGGGGTTGGCGAGTGTGTT TTGTGAAGTTTTTTAGGCACCTTTTGAAATGTAATCATTTGGGTCAATATGTAATTTTCAGTGTTAGACTAGTAAATTGTCCGCT AAATTCTGGCCGTTTTTGGCTTTTTTGTTAGACGAAGCTTGGGCCCGGGATCCATGGAAGTCGCCCCGGAACAACCACGATGG ATGGCACATCCTGCAGTTCTCAACGCACAACATCCTGATAGTCATCATCCAGGGTTGGCTCATAATTATATGGAGCCTGCCCAA CTCCTTCCCCCTGATGAAGTTGATGTGTTCTTTAACCATCTGGATTCTCAAGGAAATCCGTATTACGCTAATCCAGCCCATGCAC GCGCACGTGTTTCATATAGTCCTGCCCATGCGAGGCTTACAGGCGGGCAAATGTGTCGTCCCCATCTCCTGCATTCTCCCGGCC TGCCGTGGCTTGATGGTGGAAAGGCTGCGCTGAGCGCTGCCGCCGCTCATCATCATAATCCATGGACTGTCAGTCCGTTTTCTA AAACTCCTTTGCATCCATCTGCAGCCGGTGGACCAGGCGGTCCGCTTTCAGTTTATCCCGGTGCGGGTGGCGGCTCCGGCGGC GGTTCAGGATCAAGCGTCGCGAGCCTGACTCCAACGGCTGCTCATAGTGGTAGCCATCTGTTTGGGTTTCCCCCAACTCCCCCT AAAGAGGTCAGCCCAGATCCAAGCACGACCGGCGCCGCTTCCCCTGCATCCAGCTCTGCCGGTGGGAGCGCGGCAAGAGGG GAAGATAAAGATGGAGTGAAATATCAAGTAAGTTTGACAGAATCAATGAAAATGGAGAGCGGATCTCCTCTCCGGCCCGGGC TTGCCACAATGGGTACTCAACCAGCCACCCATCATCCTATTCCAACATATCCTAGCTACGTTCCCGCCGCCGCTCATGATTATTC ATCTGGTCTGTTTCATCCTGGCGGGTTCTTGGGCGGCCCCGCGAGCAGTTTTACACCCAAACAACGTTCTAAAGCCAGGAGCT GCAGTGAGGGTAGAGAATGCGTTAATTGCGGCGCTACTGCAACACCGCTTTGGCGAAGAGATGGTACTGGTCATTATTTGTGT AACGCATGCGGTCTGTATCATAAAATGAACGGTCAAAATCGGCCCCTGATTAAACCTAAAAGGCGGCTTAGTGCGGCAAGGC GTGCAGGAACTTGCTGCGCCAACTGCCAAACAACGACAACTACTCTCTGGAGACGGAATGCAAATGGTGATCCGGTTTGTAAT GCGTGCGGGCTGTATTATAAATTGCATAACGTCAATCGGCCGCTTACAATGAAGAAAGAGGGAATACAAACCAGAAATCGCA AAATGAGCAATAAATCTAAGAAATCTAAGAAGGGAGCAGAATGTTTTGAGGAACTCAGCAAATGTATGCAAGAAAAGTCCAG CCCTTTCTCCGCTGCAGCTTTGGCGGGGCATATGGCTCCCGTCGGTCATCTTCCACCGTTTTCTCATAGCGGTCATATTCTTCCTA CGCCCACCCCAATACATCCTTCTTCATCTTTGTCATTTGGACATCCTCATCCATCTTCTATGGTCACTGCAATGGGCGGCAGCGG CGCCACAAACTTCTCTCTGCTAAAGCAAGCAGGTGATGTTGAAGAAAACCCCGGGCCTATGATGTTTTCAGGGTTTAATGCCG ATTATGAAGCCAGTTCTTCAAGATGTTCCTCAGCTTCCCCCGCAGGCGACTCCTTGTCCTATTATCATTCTCCAGCTGATAGCTTT AGTTCCATGGGGTCCCCCGTTAATGCCCAAGACTTTTGTACTGATCTCGCGGTTAGCAGCGCAAATTTTATACCGACTGTGACA GCAATATCAACATCTCCAGATCTTCAATGGCTCGTTCAACCTGCACTGGTGAGCTCTGTCGCACCTTCACAAACGCGGGCTCCA CATCCATTTGGCGTTCCTGCACCAAGTGCAGGTGCCTATAGCCGCGCAGGGGTGGTTAAAACAATGACTGGTGGAAGAGCCC AATCCATCGGGCGCCGGGGAAAAGTAGAGCAACTGTCCCCCGAGGAAGAGGAAAAGCGTCGTATTAGGCGCGAGCGGAACA AAATGGCGGCTGCAAAGTGTAGAAATAGGCGCCGCGAATTGACAGACACCCTGCAGGCAGAAACCGATCAGCTCGAGGACG AAAAGTCCGCCCTTCAAACTGAAATCGCAAATTTGCTTAAAGAGAAAGAGAAGTTGGAATTTATACTCGCTGCCCATCGGCCA GCATGTAAAATACCCGACGATTTGGGTTTTCCCGAGGAAATGTCAGTAGCCTCTCTCGACCTTACGGGCGGACTTCCCGAAGT GGCGACTCCTGAAAGTGAAGAAGCATTTACACTTCCCCTGCTGAACGATCCAGAACCTAAACCTTCCGTCGAGCCCGTAAAATC AATTTCTTCCATGGAATTGAAAACAGAACCTTTCGACGATTTTCTCTTTCCTGCCAGTTCACGCCCATCCGGGAGTGAAACCGCT CGAAGCGTTCCGGATATGGATCTTAGCGGCAGCTTTTACGCTGCTGATTGGGAACCGCTTCATAGCGGGTCATTGGGTATGGG ACCAATGGCTACCGAACTTGAACCATTGTGTACCCCAGTTGTGACATGCACCCCTTCTTGTACCGCGTATACTTCAAGCTTTGTA TTTACATATCCTGAAGCCGATTCATTTCCAAGTTGCGCCGCCGCTCATAGGAAAGGGTCTAGTAGTAACGAACCAAGTTCAGAT TCACTGTCCAGCCCTACATTGTTGGCTCTCGGCTCCGGCGAGGGCAGGGGAAGTCTTCTAACATGCGGGGACGTGGAGGAAA ATCCCGGCCCAATGCCCCGGAGTTTTCTTGTTAAATCCAAGAAAGCCCATACATATCATCAACCTCGCGTCCAAGAGGACGAGC CACTGTGGCCCCCAGCTCTGACGCCTGTACCTCGGGATCAAGCACCGTCTAATTCTCCCGTGCTGTCAACCCTGTTTCCTAATCA ATGTCTTGATTGGACTAATCTTAAGCGCGAACCAGAACTCGAACAAGATCAAAATCTGGCACGGATGGCTCCTGCCCCCGAAG GACCAATCGTACTCTCTCGGCCTCAAGACGGCGATAGTCCCTTGTCAGATTCACCCCCATTTTATAAACCATCCTTTAGTTGGGA TACACTCGCTACTACATACGGTCATTCATATAGACAAGCTCCATCTACAATGCAATCCGCGTTTCTCGAACATAGCGTGAGTCTT TATGGTAGCCCACTGGTTCCAAGTACCGAACCGGCACTGGATTTCTCACTTCGTTATAGCCCTGGGATGGACGCTTATCATTGC GTCAAATGTAATAAAGTGTTTAGTACGCCCCATGGACTGGAAGTCCACGTAAGGCGGAGTCACTCCGGCACTAGACCTTTTGC ATGCGATATATGTGGGAAGACTTTTGGTCATGCCGTTTCCCTTGAACAACATACTCATGTGCATTCTCAAGAAAGATCCTTTGA ATGTCGGATGTGTGGAAAAGCATTTAAAAGGTCATCAACTCTCAGCACTCATTTGCTGATTCATTCTGATACCCGCCCATATCCT TGTCAATTTTGTGGTAAAAGGTTTCATCAGAAAAGCGATATGAAGAAACATACCTACATTCATACTGGAGAGAAGCCCCATAA ATGTCAAGTTTGTGGTAAGGCATTTTCACAATCTTCTAACCTGATAACACATTCCCGGAAACATACTGGATTTAAACCATTTTCT TGCGAACTCTGTACAAAGGGTTTTCAAAGAAAAGTAGATCTCCGTAGGCATCGTGAATCACAACATAACCTGAAATAAGGATC CATTCGATATCAAGCTTATCGATAATCAACCTCTGGATTACAAAATTTGTGAAAGATTGACTGGTATTCTTAACTATGTTGCTCC TTTTACGCTATGTGGATACGCTGCTTTAATGCCTTTGTATCATGCTATTGCTTCCCGTATGGCTTTCATTTTCTCCTCCTTGTATAA ATCCTGGTTGCTGTCTCTTTATGAGGAGTTGTGGCCCGTTGTCAGGCAACGTGGCGTGGTGTGCACTGTGTTTGCTGACGCAA CCCCCACTGGTTGGGGCATTGCCACCACCTGTCAGCTCCTTTCCGGGACTTTCGCTTTCCCCCTCCCTATTGCCACGGCGGAACT CATCGCCGCCTGCCTTGCCCGCTGCTGGACAGGGGCTCGGCTGTTGGGCACTGACAATTCCGTGGTGTTGTCGGGGAAATCAT CGTCCTTTCCTTGGCTGCTCGCCTGTGTTGCCACCTGGATTCTGCGCGGGACGTCCTTCTGCTACGTCCCTTCGGCCCTCAATCC AGCGGACCTTCCTTCCCGCGGCCTGCTGCCGGCTCTGCGGCCTCTTCCGCGTCTTCGCCTTCGCCCTCAGACGAGTCGGATCTC CCTTTGGGCCGCCTCCCCGCATCGATACCGTCGACCTCGAGACCTAGAAAAACATGGAGCAATCACAAGTAGCAATACAGCAG CTACCAATGCTGATTGTGCCTGGCTAGAAGCACAAGAGGAGGAGGAGGTGGGTTTTCCAGTCACACCTCAGGTACCTTTAAGA CCAATGACTTACAAGGCAGCTGTAGATCTTAGCCACTTTTTAAAAGAAAAGGGGGGACTGGAAGGGCTAATTCACTCCCAACG AAGACAAGATATCCTTGATCTGTGGATCTACCACACACAAGGCTACTTCCCTGATTGGCAGAACTACACACCAGGGCCAGGGA TCAGATATCCACTGACCTTTGGATGGTGCTACAAGCTAGTACCAGTTGAGCAAGAGAAGGTAGAAGAAGCCAATGAAGGAGA GAACACCCGCTTGTTACACCCTGTGAGCCTGCATGGGATGGATGACCCGGAGAGAGAAGTATTAGAGTGGAGGTTTGACAGC CGCCTAGCATTTCATCACATGGCCCGAGAGCTGCATCCGGACTGTACTGGGTCTCTCTGGTTAGACCAGATCTGAGCCTGGGA GCTCTCTGGCTAACTAGGGAACCCACTGCTTAAGCCTCAATAAAGCTTGCCTTGAGTGCTTCAAGTAGTGTGTGCCCGTCTGTT GTGTGACTCTGGTAACTAGAGATCCCTCAGACCCTTTTAGTCAGTGTGGAAAATCTCTAGCAGGGCCCGTTTAAACCCGCTGAT CAGCCTCGACTGTGCCTTCTAGTTGCCAGCCATCTGTTGTTTGCCCCTCCCCCGTGCCTTCCTTGACCCTGGAAGGTGCCACTCC CACTGTCCTTTCCTAATAAAATGAGGAAATTGCATCGCATTGTCTGAGTAGGTGTCATTCTATTCTGGGGGGTGGGGTGGGGC AGGACAGCAAGGGGGAGGATTGGGAAGACAATAGCAGGCATGTGAGCAAAAGGCCAGCAAAAGGCCAGGAACCGTAAAAA GGCCGCGTTGCTGGCGTTTTTCCATAGGCTCCGCCCCCCTGACGAGCATCACAAAAATCGACGCTCAAGTCAGAGGTGGCGAA ACCCGACAGGACTATAAAGATACCAGGCGTTTCCCCCTGGAAGCTCCCTCGTGCGCTCTCCTGTTCCGACCCTGCCGCTTACCG GATACCTGTCCGCCTTTCTCCCTTCGGGAAGCGTGGCGCTTTCTCATAGCTCACGCTGTAGGTATCTCAGTTCGGTGTAGGTCG TTCGCTCCAAGCTGGGCTGTGTGCACGAACCCCCCGTTCAGCCCGACCGCTGCGCCTTATCCGGTAACTATCGTCTTGAGTCCA ACCCGGTAAGACACGACTTATCGCCACTGGCAGCAGCCACTGGTAACAGGATTAGCAGAGCGAGGTATGTAGGCGGTGCTAC AGAGTTCTTGAAGTGGTGGCCTAACTACGGCTACACTAGAAGAACAGTATTTGGTATCTGCGCTCTGCTGAAGCCAGTTACCTT CGGAAAAAGAGTTGGTAGCTCTTGATCCGGCAAACAAACCACCGCTGGTAGCGGTGGTTTTTTTGTTTGCAAGCAGCAGATTA CGCGCAGAAAAAAAGGATCTCAAGAAGATCCTTTGATCTTTTCTACGGGGTCTGACGCTCAGTGGAACGAAAACTCACGTTAA GGGATTTTGGTCATGAGATTATCAAAAAGGATCTTCACCTAGATCCTTTTAAATTAAAAATGAAGTTTTAAATCAATCTAAAGTA TATATGAGTAAACTTGGTCTGACAGTTACCAATGCTTAATCAGTGAGGCACCTATCTCAGCGATCTGTCTATTTCGTTCATCCAT AGTTGCCTGACTCCCCGTCGTGTAGATAACTACGATACGGGAGGGCTTACCATCTGGCCCCAGTGCTGCAATGATACCGCGAG ACCCACGCTCACCGGCTCCAGATTTATCAGCAATAAACCAGCCAGCCGGAAGGGCCGAGCGCAGAAGTGGTCCTGCAACTTTA TCCGCCTCCATCCAGTCTATTAATTGTTGCCGGGAAGCTAGAGTAAGTAGTTCGCCAGTTAATAGTTTGCGCAACGTTGTTGCC ATTGCTACAGGCATCGTGGTGTCACGCTCGTCGTTTGGTATGGCTTCATTCAGCTCCGGTTCCCAACGATCAAGGCGAGTTACA TGATCCCCCATGTTGTGCAAAAAAGCGGTTAGCTCCTTCGGTCCTCCGATCGTTGTCAGAAGTAAGTTGGCCGCAGTGTTATCA CTCATGGTTATGGCAGCACTGCATAATTCTCTTACTGTCATGCCATCCGTAAGATGCTTTTCTGTGACTGGTGAGTACTCAACCA AGTCATTCTGAGAATAGTGTATGCGGCGACCGAGTTGCTCTTGCCCGGCGTCAATACGGGATAATACCGCGCCACATAGCAGA ACTTTAAAAGTGCTCATCATTGGAAAACGTTCTTCGGGGCGAAAACTCTCAAGGATCTTACCGCTGTTGAGATCCAGTTCGATG TAACCCACTCGTGCACCCAACTGATCTTCAGCATCTTTTACTTTCACCAGCGTTTCTGGGTGAGCAAAAACAGGAAGGCAAAAT GCCGCAAAAAAGGGAATAAGGGCGACACGGAAATGTTGAATACTCATACTCTTCCTTTTTCAATATTATTGAAGCATTTATCAG GGTTATTGTCTCATGAGCGGATACATATTTGAATGTATTTAGAAAAATAAACAAATAGGGGTTCCGCGCACATTTCCCCGAAAA GTGCCACCTGACG SEQIDNo.22-FUW-GiGaFo(vector3) tcgacggatcgggagatctcccgatcccctatggtgcactctcagtacaatctgctctgatgccgcatagttaagccagtatctgctccctgcttgtgtgttggaggtcgc tgagtagtgcgcgagcaaaatttaagctacaacaaggcaaggcttgaccgacaattgcatgaagaatctgcttagggttaggcgttttgcgctgcttcgcgatgtacg ggccagatatacgcgttgacattgattattgactagttattaatagtaatcaattacggggtcattagttcatagcccatatatggagttccgcgttacataacttacggt aaatggcccgcctggctgaccgcccaacgacccccgcccattgacgtcaataatgacgtatgttcccatagtaacgccaatagggactttccattgacgtcaatgggt ggagtatttacggtaaactgcccacttggcagtacatcaagtgtatcatatgccaagtacgccccctattgacgtcaatgacggtaaatggcccgcctggcattatgcc cagtacatgaccttatgggactttcctacttggcagtacatctacgtattagtcatcgctattaccatggtgatgcggttttggcagtacatcaatgggcgtggatagcgg tttgactcacggggatttccaagtctccaccccattgacgtcaatgggagtttgttttggcaccaaaatcaacgggactttccaaaatgtcgtaacaactccgccccatt gacgcaaatgggcggtaggcgtgtacggtgggaggtctatataagcagcgcgttttgcctgtactgggtctctctggttagaccagatctgagcctgggagctctctgg ctaactagggaacccactgcttaagcctcaataaagcttgccttgagtgcttcaagtagtgtgtgcccgtctgttgtgtgactctggtaactagagatccctcagaccctt ttagtcagtgtggaaaatctctagcagtggcgcccgaacagggacttgaaagcgaaagggaaaccagaggagctctctcgacgcaggactcggcttgctgaagcgc gcacggcaagaggcgaggggcggcgactggtgagtacgccaaaaattttgactagcggaggctagaaggagagagatgggtgcgagagcgtcagtattaagcgg gggagaattagatcgcgatgggaaaaaattcggttaaggccagggggaaagaaaaaatataaattaaaacatatagtatgggcaagcagggagctagaacgattc gcagttaatcctggcctgttagaaacatcagaaggctgtagacaaatactgggacagctacaaccatcccttcagacaggatcagaagaacttagatcattatataat acagtagcaaccctctattgtgtgcatcaaaggatagagataaaagacaccaaggaagctttagacaagatagaggaagagcaaaacaaaagtaagaccaccgc acagcaagcggccgctgatcttcagacctggaggaggagatatgagggacaattggagaagtgaattatataaatataaagtagtaaaaattgaaccattaggagt agcacccaccaaggcaaagagaagagtggtgcagagagaaaaaagagcagtgggaataggagctttgttccttgggttcttgggagcagcaggaagcactatggg cgcagcgtcaatgacgctgacggtacaggccagacaattattgtctggtatagtgcagcagcagaacaatttgctgagggctattgaggcgcaacagcatctgttgca actcacagtctggggcatcaagcagctccaggcaagaatcctggctgtggaaagatacctaaaggatcaacagctcctggggatttggggttgctctggaaaactcat ttgcaccactgctgtgccttggaatgctagttggagtaataaatctctggaacagatttggaatcacacgacctggatggagtgggacagagaaattaacaattacac aagcttaatacactccttaattgaagaatcgcaaaaccagcaagaaaagaatgaacaagaattattggaattagataaatgggcaagtttgtggaattggtttaaca taacaaattggctgtggtatataaaattattcataatgatagtaggaggcttggtaggtttaagaatagtttttgctgtactttctatagtgaatagagttaggcagggat attcaccattatcgtttcagacccacctcccaaccccgaggggacccgacaggcccgaaggaatagaagaagaaggtggagagagagacagagacagatccattc gattagtgaacggatcggcactgcgtgcgccaattctgcagacaaatggcagtattcatccacaattttaaaagaaaaggggggattggggggtacagtgcagggg aaagaatagtagacataatagcaacagacatacaaactaaagaattacaaaaacaaattacaaaaattcaaaattttcgggtttattacagggacagcagagatcc agtttggttaattaacccgtgtcggctccagatctggcctccgcgccgggttttggcgcctcccgcgggcgcccccctcctcacggcgagcgctgccacgtcagacgaa gggcgcagcgagcgtcctgatccttccgcccggacgctcaggacagcggcccgctgctcataagactcggccttagaaccccagtatcagcagaaggacattttagg acgggacttgggtgactctagggcactggttttctttccagagagcggaacaggcgaggaaaagtagtcccttctcggcgattctgcggagggatctccgtggggcgg tgaacgccgatgattatataaggacgcgccgggtgtggcacagctagttccgtcgcagccgggatttgggtcgcggttcttgtttgtggatcgctgtgatcgtcacttgg tgagtagcgggctgctgggctggccggggctttcgtggccgccgggccgctcggtgggacggaagcgtgtggagagaccgccaagggctgtagtctgggtccgcgag caaggttgccctgaactgggggttggggggagcgcagcaaaatggcggctgttcccgagtcttgaatggaagacgcttgtgaggcgggctgtgaggtcgttgaaaca aggtggggggcatggtgggcggcaagaacccaaggtcttgaggccttcgctaatgcgggaaagctcttattcgggtgagatgggctggggcaccatctggggaccct gacgtgaagtttgtcactgactggagaactcggtttgtcgtctgttgcgggggcggcagttatggcggtgccgttgggcagtgcacccgtacctttgggagcgcgcgcc ctcgtcgtgtcgtgacgtcacccgttctgttggcttataatgcagggtggggccacctgccggtaggtgtgcggtaggcttttctccgtcgcaggacgcagggttcgggc ctagggtaggctctcctgaatcgacaggcgccggacctctggtgaggggagggataagtgaggcgtcagtttctttggtcggttttatgtacctatcttcttaagtagct gaagctccggttttgaactatgcgctcggggttggcgagtgtgttttgtgaagttttttaggcaccttttgaaatgtaatcatttgggtcaatatgtaattttcagtgttaga ctagtaaattgtccgctaaattctggccgtttttggcttttttgttagacgaagcttgggcccgggatccATGCCCAGAAGCTTTCTCGTCAAATCAAAGAA AGCCCATACATATCATCAACCTCGGGTTCAAGAGGACGAGCCTTTGTGGCCACCAGCTCTCACACCAGTCCCTCGGGATCAAGC CCCTTCAAATAGTCCAGTACTCTCTACACTCTTTCCTAATCAATGTTTGGATTGGACAAATCTGAAGCGGGAACCAGAACTTGAA CAAGATCAAAATCTGGCACGGATGGCACCTGCGCCTGAAGGACCAATCGTCTTGTCTAGGCCTCAAGACGGCGATAGCCCGCT CAGCGATTCCCCACCGTTTTATAAACCCAGTTTTAGCTGGGATACACTGGCTACGACATACGGACATTCATATAGGCAAGCTCC TAGTACTATGCAATCCGCATTTCTCGAACATAGCGTGTCTTTGTATGGGAGCCCGCTCGTACCTTCTACCGAACCTGCGCTGGA TTTTAGTCTGCGTTATAGCCCTGGGATGGACGCCTATCATTGCGTCAAATGTAATAAAGTCTTTAGCACTCCCCATGGCCTGGA AGTCCACGTCCGGCGAAGTCACTCTGGTACTAGACCATTTGCTTGCGATATTTGTGGAAAGACTTTTGGACATGCCGTCAGTCT TGAACAACATACACATGTGCATTCTCAAGAACGGTCCTTTGAATGTCGGATGTGTGGGAAAGCTTTTAAAAGAAGCTCTACTCT CTCAACGCATCTCTTGATTCATAGCGATACACGTCCTTATCCATGTCAATTTTGTGGAAAACGCTTCCATCAAAAGTCAGATATG AAGAAACATACTTATATTCATACTGGCGAGAAACCACACAAATGTCAAGTTTGCGGCAAAGCATTTTCCCAATCCTCAAATCTG ATTACTCATTCCAGAAAACATACTGGGTTTAAACCATTTTCCTGCGAACTTTGTACGAAGGGTTTTCAAAGGAAAGTTGATTTG CGACGCCATAGAGAATCCCAACATAACCTGAAAGGCAGCGGCGCCACAAACTTCTCTCTGCTAAAGCAAGCAGGTGATGTTGA AGAAAACCCCGGGCCTATGGAAGTTGCCCCTGAACAACCAAGATGGATGGCCCATCCCGCGGTCCTCAACGCCCAACATCCAG ATTCTCATCATCCCGGTCTTGCCCATAATTATATGGAGCCTGCCCAACTTTTGCCCCCAGATGAAGTAGATGTATTCTTCAACCA TCTGGATTCCCAAGGAAATCCTTATTACGCAAATCCAGCCCATGCACGCGCCAGGGTGAGCTATTCTCCAGCCCATGCAAGGCT TACGGGCGGACAAATGTGTAGACCTCATCTGCTCCATAGTCCAGGCCTGCCATGGCTTGATGGCGGTAAGGCCGCGCTTAGCG CTGCAGCAGCTCATCATCATAATCCATGGACTGTCTCCCCATTTAGCAAAACACCGCTTCATCCTTCTGCAGCAGGTGGGCCGG GCGGACCTCTGAGCGTATATCCTGGCGCAGGTGGCGGCTCCGGCGGCGGGTCAGGAAGTAGTGTCGCGAGCCTGACTCCAAC CGCTGCTCATAGCGGGAGTCATCTGTTTGGGTTTCCGCCAACACCCCCTAAAGAGGTATCCCCAGATCCATCTACTACCGGTGC CGCCAGTCCCGCAAGCTCCAGTGCAGGCGGCAGCGCTGCTAGAGGTGAAGATAAAGATGGGGTGAAATATCAAGTTTCCCTC ACCGAAAGTATGAAAATGGAGTCCGGAAGCCCACTTCGACCTGGTCTTGCCACCATGGGAACACAACCCGCCACCCATCATCC TATACCAACGTATCCAAGCTACGTCCCCGCTGCAGCTCATGATTATTCATCAGGGCTGTTTCATCCTGGTGGATTCTTGGGCGG TCCTGCTTCAAGTTTTACTCCGAAACAACGGTCTAAAGCCAGGAGCTGCTCCGAGGGAAGGGAATGCGTGAATTGCGGAGCA ACCGCTACTCCCCTTTGGCGAAGGGATGGTACTGGTCATTATCTTTGTAACGCATGCGGGCTGTATCATAAAATGAACGGCCA AAATCGGCCCCTGATTAAACCAAAACGGAGACTTTCCGCTGCACGGCGTGCTGGGACATGCTGCGCTAACTGCCAAACCACCA CTACAACTCTCTGGCGGCGGAATGCTAATGGTGATCCAGTGTGTAATGCTTGCGGGCTGTATTACAAACTTCATAACGTGAATC GCCCTCTTACGATGAAGAAAGAGGGAATTCAAACGCGTAATCGTAAAATGTCAAATAAATCAAAGAAATCTAAGAAGGGTGC TGAATGTTTTGAGGAACTCAGCAAATGTATGCAAGAGAAAAGCAGCCCTTTTAGCGCGGCGGCGCTTGCAGGGCATATGGCC CCAGTAGGTCATCTGCCCCCGTTTTCTCATAGCGGTCATATTCTCCCAACCCCAACACCGATACATCCAAGCAGCTCCTTGTCTTT TGGGCATCCTCATCCAAGCTCAATGGTCACAGCAATGGGCGGCTCCGGCGAGGGCAGGGGAAGTCTTCTAACATGCGGGGAC GTGGAGGAAAATCCCGGCCCAATGATGTTTTCAGGGTTTAATGCCGATTATGAAGCCAGTTCATCTCGATGTTCATCAGCCAGC CCTGCTGGCGACTCACTGAGCTATTATCATTCTCCAGCTGATTCATTTTCTTCTATGGGGAGCCCAGTAAATGCACAAGACTTTT GTACCGATCTCGCAGTTTCAAGCGCGAATTTTATCCCAACCGTGACCGCTATTAGCACTTCTCCAGATCTCCAATGGCTTGTCCA ACCGGCTCTGGTGAGTAGCGTCGCTCCGAGCCAAACGAGGGCACCCCATCCGTTTGGTGTACCAGCACCAAGCGCAGGAGCA TATTCTCGCGCGGGTGTAGTCAAAACAATGACTGGCGGGCGCGCCCAAAGTATCGGTCGCAGAGGTAAAGTAGAGCAACTGA GCCCCGAGGAAGAGGAAAAGCGACGGATTAGACGTGAGCGGAACAAAATGGCCGCCGCTAAGTGTCGGAATAGACGACGA GAACTTACAGACACTCTGCAGGCCGAAACCGATCAGTTGGAAGACGAAAAGTCCGCACTCCAAACAGAAATCGCGAATCTTTT GAAAGAGAAAGAGAAGCTCGAATTTATTCTTGCCGCACATCGCCCCGCGTGTAAAATACCCGACGATCTTGGATTTCCTGAGG AAATGTCCGTTGCAAGCCTGGACCTCACCGGCGGACTTCCGGAAGTCGCAACACCCGAAAGTGAAGAAGCTTTTACTCTTCCC CTGCTGAACGATCCCGAACCTAAACCTTCTGTTGAGCCCGTTAAATCAATAAGTAGTATGGAACTCAAAACTGAACCATTCGAC GATTTTCTGTTTCCCGCTTCCAGTAGACCAAGCGGGAGCGAAACTGCACGATCTGTCCCGGATATGGATCTGTCAGGCTCATTT TACGCGGCCGATTGGGAACCACTCCATTCCGGATCTCTCGGCATGGGACCAATGGCTACCGAACTTGAACCACTTTGTACCCCC GTCGTAACGTGCACACCATCCTGTACCGCGTATACTAGCTCTTTTGTATTTACTTATCCGGAAGCGGATTCATTTCCAAGTTGCG CCGCCGCTCATAGAAAAGGGTCTTCATCTAACGAACCGTCTTCCGATTCCCTGAGTAGTCCTACCCTTTTGGCATTGTAAggatcc attcgatatcaagcttatcgataatcaacctctggattacaaaatttgtgaaagattgactggtattcttaactatgttgctccttttacgctatgtggatacgctgcttta atgcctttgtatcatgctattgcttcccgtatggctttcattttctcctccttgtataaatcctggttgctgtctctttatgaggagttgtggcccgttgtcaggcaacgtggc gtggtgtgcactgtgtttgctgacgcaacccccactggttggggcattgccaccacctgtcagctcctttccgggactttcgctttccccctccctattgccacggcggaa ctcatcgccgcctgccttgcccgctgctggacaggggctcggctgttgggcactgacaattccgtggtgttgtcggggaaatcatcgtcctttccttggctgctcgcctgt gttgccacctggattctgcgcgggacgtccttctgctacgtcccttcggccctcaatccagcggaccttccttcccgcggcctgctgccggctctgcggcctcttccgcgtc ttcgccttcgccctcagacgagtcggatctccctttgggccgcctccccgcatcgataccgtcgacctcgagacctagaaaaacatggagcaatcacaagtagcaata cagcagctaccaatgctgattgtgcctggctagaagcacaagaggaggaggaggtgggttttccagtcacacctcaggtacctttaagaccaatgacttacaaggca gctgtagatcttagccactttttaaaagaaaaggggggactggaagggctaattcactcccaacgaagacaagatatccttgatctgtggatctaccacacacaaggc tacttccctgattggcagaactacacaccagggccagggatcagatatccactgacctttggatggtgctacaagctagtaccagttgagcaagagaaggtagaaga agccaatgaaggagagaacacccgcttgttacaccctgtgagcctgcatgggatggatgacccggagagagaagtattagagtggaggtttgacagccgcctagca tttcatcacatggcccgagagctgcatccggactgtactgggtctctctggttagaccagatctgagcctgggagctctctggctaactagggaacccactgcttaagcc tcaataaagcttgccttgagtgcttcaagtagtgtgtgcccgtctgttgtgtgactctggtaactagagatccctcagacccttttagtcagtgtggaaaatctctagcag ggcccgtttaaacccgctgatcagcctcgactgtgccttctagttgccagccatctgttgtttgcccctcccccgtgccttccttgaccctggaaggtgccactcccactgt cctttcctaataaaatgaggaaattgcatcgcattgtctgagtaggtgtcattctattctggggggtggggggggcaggacagcaagggggaggattgggaagaca atagcaggcatgtgagcaaaaggccagcaaaaggccaggaaccgtaaaaaggccgcgttgctggcgtttttccataggctccgcccccctgacgagcatcacaaaa atcgacgctcaagtcagaggtggcgaaacccgacaggactataaagataccaggcgtttccccctggaagctccctcgtgcgctctcctgttccgaccctgccgcttac cggatacctgtccgcctttctcccttcgggaagcgtggcgctttctcatagctcacgctgtaggtatctcagttcggtgtaggtcgttcgctccaagctgggctgtgtgca cgaaccccccgttcagcccgaccgctgcgccttatccggtaactatcgtcttgagtccaacccggtaagacacgacttatcgccactggcagcagccactggtaacag gattagcagagcgaggtatgtaggcggtgctacagagttcttgaagtggtggcctaactacggctacactagaagaacagtatttggtatctgcgctctgctgaagcc agttaccttcggaaaaagagttggtagctcttgatccggcaaacaaaccaccgctggtagcggtggtttttttgtttgcaagcagcagattacgcgcagaaaaaaagg atctcaagaagatcctttgatcttttctacggggtctgacgctcagtggaacgaaaactcacgttaagggattttggtcatgagattatcaaaaaggatcttcacctaga tccttttaaattaaaaatgaagttttaaatcaatctaaagtatatatgagtaaacttggtctgacagttaccaatgcttaatcagtgaggcacctatctcagcgatctgtc tatttcgttcatccatagttgcctgactccccgtcgtgtagataactacgatacgggagggcttaccatctggccccagtgctgcaatgataccgcgagacccacgctca ccggctccagatttatcagcaataaaccagccagccggaagggccgagcgcagaagtggtcctgcaactttatccgcctccatccagtctattaattgttgccgggaa gctagagtaagtagttcgccagttaatagtttgcgcaacgttgttgccattgctacaggcatcgtggtgtcacgctcgtcgtttggtatggcttcattcagctccggttccc aacgatcaaggcgagttacatgatcccccatgttgtgcaaaaaagcggttagctccttcggtcctccgatcgttgtcagaagtaagttggccgcagtgttatcactcatg gttatggcagcactgcataattctcttactgtcatgccatccgtaagatgcttttctgtgactggtgagtactcaaccaagtcattctgagaatagtgtatgcggcgaccg agttgctcttgcccggcgtcaatacgggataataccgcgccacatagcagaactttaaaagtgctcatcattggaaaacgttcttcggggcgaaaactctcaaggatct taccgctgttgagatccagttcgatgtaacccactcgtgcacccaactgatcttcagcatcttttactttcaccagcgtttctgggtgagcaaaaacaggaaggcaaaat gccgcaaaaaagggaataagggcgacacggaaatgttgaatactcatactcttcctttttcaatattattgaagcatttatcagggttattgtctcatgagcggatacat atttgaatgtatttagaaaaataaacaaataggggttccgcgcacatttccccgaaaagtgccacctgacg SEQIDNo.23-FUW-GiFoGa(vector4) tcgacggatcgggagatctcccgatcccctatggtgcactctcagtacaatctgctctgatgccgcatagttaagccagtatctgctccctgcttgtgtgttggaggtcgc tgagtagtgcgcgagcaaaatttaagctacaacaaggcaaggcttgaccgacaattgcatgaagaatctgcttagggttaggcgttttgcgctgcttcgcgatgtacg ggccagatatacgcgttgacattgattattgactagttattaatagtaatcaattacggggtcattagttcatagcccatatatggagttccgcgttacataacttacggt aaatggcccgcctggctgaccgcccaacgacccccgcccattgacgtcaataatgacgtatgttcccatagtaacgccaatagggactttccattgacgtcaatgggt ggagtatttacggtaaactgcccacttggcagtacatcaagtgtatcatatgccaagtacgccccctattgacgtcaatgacggtaaatggcccgcctggcattatgcc cagtacatgaccttatgggactttcctacttggcagtacatctacgtattagtcatcgctattaccatggtgatgcggttttggcagtacatcaatgggcgtggatagcgg tttgactcacggggatttccaagtctccaccccattgacgtcaatgggagtttgttttggcaccaaaatcaacgggactttccaaaatgtcgtaacaactccgccccatt gacgcaaatgggcggtaggcgtgtacggtgggaggtctatataagcagcgcgttttgcctgtactgggtctctctggttagaccagatctgagcctgggagctctctgg ctaactagggaacccactgcttaagcctcaataaagcttgccttgagtgcttcaagtagtgtgtgcccgtctgttgtgtgactctggtaactagagatccctcagaccctt ttagtcagtgtggaaaatctctagcagtggcgcccgaacagggacttgaaagcgaaagggaaaccagaggagctctctcgacgcaggactcggcttgctgaagcgc gcacggcaagaggcgaggggcggcgactggtgagtacgccaaaaattttgactagcggaggctagaaggagagagatgggtgcgagagcgtcagtattaagcgg gggagaattagatcgcgatgggaaaaaattcggttaaggccagggggaaagaaaaaatataaattaaaacatatagtatgggcaagcagggagctagaacgattc gcagttaatcctggcctgttagaaacatcagaaggctgtagacaaatactgggacagctacaaccatcccttcagacaggatcagaagaacttagatcattatataat acagtagcaaccctctattgtgtgcatcaaaggatagagataaaagacaccaaggaagctttagacaagatagaggaagagcaaaacaaaagtaagaccaccgc acagcaagcggccgctgatcttcagacctggaggaggagatatgagggacaattggagaagtgaattatataaatataaagtagtaaaaattgaaccattaggagt agcacccaccaaggcaaagagaagagtggtgcagagagaaaaaagagcagtgggaataggagctttgttccttgggttcttgggagcagcaggaagcactatggg cgcagcgtcaatgacgctgacggtacaggccagacaattattgtctggtatagtgcagcagcagaacaatttgctgagggctattgaggcgcaacagcatctgttgca actcacagtctggggcatcaagcagctccaggcaagaatcctggctgtggaaagatacctaaaggatcaacagctcctggggatttggggttgctctggaaaactcat ttgcaccactgctgtgccttggaatgctagttggagtaataaatctctggaacagatttggaatcacacgacctggatggagtgggacagagaaattaacaattacac aagcttaatacactccttaattgaagaatcgcaaaaccagcaagaaaagaatgaacaagaattattggaattagataaatgggcaagtttgtggaattggtttaaca taacaaattggctgtggtatataaaattattcataatgatagtaggaggcttggtaggtttaagaatagtttttgctgtactttctatagtgaatagagttaggcagggat attcaccattatcgtttcagacccacctcccaaccccgaggggacccgacaggcccgaaggaatagaagaagaaggtggagagagagacagagacagatccattc gattagtgaacggatcggcactgcgtgcgccaattctgcagacaaatggcagtattcatccacaattttaaaagaaaaggggggattggggggtacagtgcagggg aaagaatagtagacataatagcaacagacatacaaactaaagaattacaaaaacaaattacaaaaattcaaaattttcgggtttattacagggacagcagagatcc agtttggttaattaacccgtgtcggctccagatctggcctccgcgccgggttttggcgcctcccggggcgcccccctcctcacggcgagcgctgccacgtcagacgaa gggcgcagcgagcgtcctgatccttccgcccggacgctcaggacagcggcccgctgctcataagactcggccttagaaccccagtatcagcagaaggacattttagg acgggacttgggtgactctagggcactggttttctttccagagagcggaacaggcgaggaaaagtagtcccttctcggcgattctgcggagggatctccgtggggcgg tgaacgccgatgattatataaggacgcgccgggtgtggcacagctagttccgtcgcagccgggatttgggtcgcggttcttgtttgtggatcgctgtgatcgtcacttgg tgagtagcgggctgctgggctggccggggctttcgtggccgccgggccgctcggtgggacggaagcgtgtggagagaccgccaagggctgtagtctgggtccgcgag caaggttgccctgaactgggggttggggggagcgcagcaaaatggcggctgttcccgagtcttgaatggaagacgcttgtgaggcgggctgtgaggtcgttgaaaca aggtggggggcatggtgggcggcaagaacccaaggtcttgaggccttcgctaatgcgggaaagctcttattcgggtgagatgggctggggcaccatctggggaccct gacgtgaagtttgtcactgactggagaactcggtttgtcgtctgttgcgggggcggcagttatggcggtgccgttgggcagtgcacccgtacctttgggagcgcgcgcc ctcgtcgtgtcgtgacgtcacccgttctgttggcttataatgcagggtggggccacctgccggtaggtgtgcggtaggcttttctccgtcgcaggacgcagggttcgggc ctagggtaggctctcctgaatcgacaggcgccggacctctggtgaggggagggataagtgaggcgtcagtttctttggtcggttttatgtacctatcttcttaagtagct gaagctccggttttgaactatgcgctcggggttggcgagtgtgttttgtgaagttttttaggcaccttttgaaatgtaatcatttgggtcaatatgtaattttcagtgttaga ctagtaaattgtccgctaaattctggccgtttttggcttttttgttagacgaagcttgggcccgggatccATGCCGAGATCATTTCTCGTCAAAAGTAAGAA GGCGCATACTTATCATCAACCTCGCGTTCAAGAGGACGAGCCCTTGTGGCCCCCAGCGTTGACACCTGTTCCTCGCGATCAAGC ACCCTCTAATAGTCCCGTGCTCTCAACCCTGTTTCCTAATCAATGTTTGGATTGGACAAATCTGAAGCGTGAACCTGAATTGGA ACAAGATCAAAATCTTGCACGCATGGCGCCAGCGCCTGAAGGTCCAATCGTCCTCAGTAGACCACAAGACGGAGATAGCCCGT TGAGCGATTCTCCACCCTTTTATAAACCATCCTTTAGTTGGGATACACTGGCAACGACATACGGACATAGTTATAGGCAAGCTC CATCTACTATGCAATCTGCGTTTCTGGAACATAGCGTTTCTCTTTATGGGTCTCCGCTGGTTCCATCAACAGAACCTGCGCTGGA TTTTAGCCTGAGATATAGTCCTGGGATGGACGCATATCATTGCGTAAAATGTAATAAAGTGTTTAGCACACCACATGGCCTGG AAGTCCACGTTCGGCGGAGCCACAGCGGCACAAGGCCATTTGCATGCGATATTTGTGGGAAGACGTTTGGACATGCCGTTTCC CTCGAACAACATACACATGTTCATAGCCAAGAAAGATCATTTGAATGTAGAATGTGTGGGAAAGCATTTAAACGGTCTAGCAC ACTCTCTACGCATCTCCTGATTCATAGCGATACTCGCCCATATCCTTGTCAATTTTGCGGGAAAAGATTTCATCAAAAGTCAGAT ATGAAGAAGCATACGTATATTCATACCGGGGAGAAACCACATAAATGTCAAGTCTGTGGCAAAGCCTTTTCCCAGTCATCTAAT TTGATAACACATAGTAGGAAACATACCGGTTTTAAACCGTTTTCTTGCGAACTCTGTACAAAGGGTTTTCAAAGAAAAGTTGAT CTCCGTAGACATAGGGAATCCCAACATAACCTGAAAGGCAGCGGCGCCACAAACTTCTCTCTGCTAAAGCAAGCAGGTGATGT TGAAGAAAACCCCGGGCCTATGATGTTTAGCGGATTTAATGCCGATTATGAAGCAAGCTCAAGCAGGTGTTCCTCAGCTTCTCC CGCTGGAGACTCTCTGTCATATTATCATAGCCCAGCCGATAGCTTTTCTTCCATGGGTTCCCCAGTTAATGCTCAAGATTTCTGT ACCGATCTCGCGGTGAGTAGCGCAAATTTTATACCAACCGTGACCGCTATTTCTACATCTCCCGATCTTCAATGGTTGGTCCAAC CTGCTCTGGTGAGTTCTGTCGCACCCTCTCAAACTCGGGCACCGCATCCCTTTGGCGTACCAGCACCAAGCGCCGGAGCCTATA GCCGGGCAGGGGTGGTCAAAACTATGACCGGTGGGCGTGCCCAATCCATAGGACGCCGCGGGAAAGTCGAGCAATTGAGCC CGGAAGAAGAGGAAAAGCGGCGCATTCGCCGGGAGCGAAACAAAATGGCCGCCGCTAAGTGTCGTAATAGACGCCGCGAAC TCACCGACACGTTGCAGGCTGAAACCGATCAGCTCGAGGACGAGAAAAGTGCGCTCCAAACGGAAATCGCTAATCTTCTCAAA GAAAAGGAGAAGCTTGAATTTATTTTGGCCGCCCATCGCCCCGCTTGTAAAATACCGGACGATCTTGGGTTTCCCGAGGAAAT GAGTGTCGCCTCTCTGGACCTCACCGGCGGATTGCCTGAAGTGGCTACACCAGAATCCGAAGAAGCGTTTACGCTCCCCCTGC TGAACGATCCCGAACCAAAACCATCCGTTGAGCCAGTGAAATCAATATCATCCATGGAACTTAAAACAGAACCTTTCGACGATT TTCTGTTTCCTGCCAGCTCACGCCCGAGCGGTTCAGAAACCGCGAGGTCTGTACCCGATATGGATCTGTCAGGTTCATTTTACG CTGCCGATTGGGAACCCTTGCATAGCGGTTCTTTGGGCATGGGACCTATGGCTACCGAACTCGAACCTCTCTGTACACCTGTCG TGACATGCACACCTTCTTGTACCGCCTATACCTCAAGTTTTGTGTTTACTTATCCAGAAGCCGATAGCTTTCCTAGTTGCGCTGCC GCACATCGTAAAGGAAGTTCCTCAAACGAACCGAGTTCCGATTCTCTTAGTAGCCCAACCCTTTTGGCACTTGGCTCCGGCGAG GGCAGGGGAAGTCTTCTAACATGCGGGGACGTGGAGGAAAATCCCGGCCCAATGGAAGTCGCCCCAGAACAACCTAGGTGG ATGGCCCATCCTGCAGTACTCAACGCCCAACATCCTGATAGTCATCATCCCGGATTGGCACATAATTATATGGAGCCGGCTCAA CTCCTTCCCCCGGATGAAGTCGATGTTTTCTTTAACCATTTGGATAGTCAAGGAAATCCATATTACGCGAATCCTGCCCATGCCC GTGCCAGGGTGAGCTATTCCCCTGCCCATGCTAGACTCACTGGTGGTCAAATGTGTAGGCCCCATCTTCTCCATTCCCCTGGAC TGCCTTGGTTGGATGGCGGAAAGGCTGCTCTGTCCGCTGCCGCCGCACATCATCATAATCCTTGGACAGTCAGTCCTTTTAGCA AAACACCACTCCATCCTTCTGCTGCCGGCGGACCCGGCGGTCCTCTGTCAGTTTATCCGGGCGCTGGTGGCGGCTCTGGTGGT GGATCAGGTTCTTCCGTCGCAAGCCTGACTCCCACTGCCGCGCATTCCGGTAGCCATCTCTTTGGTTTTCCCCCTACACCCCCAA AGGAAGTCTCCCCCGATCCCTCAACTACTGGCGCGGCTAGTCCTGCGTCCTCTTCTGCCGGCGGCAGCGCTGCTCGCGGTGAA GATAAAGATGGAGTGAAATATCAAGTTAGCCTCACCGAATCTATGAAAATGGAGAGCGGATCTCCTTTGCGTCCCGGGTTGGC CACCATGGGTACACAACCAGCCACCCATCATCCTATTCCTACTTATCCGAGCTACGTACCTGCTGCCGCACATGATTATTCATCT GGGCTGTTTCATCCAGGCGGGTTTCTCGGTGGCCCCGCAAGCTCATTTACTCCCAAACAAAGGTCCAAAGCGCGGAGCTGCAG TGAGGGGAGAGAATGCGTGAATTGCGGCGCAACCGCTACGCCCTTGTGGAGAAGGGATGGAACGGGGCATTATCTCTGTAA CGCATGCGGGTTGTATCATAAAATGAACGGCCAAAATCGCCCCTTGATAAAACCAAAGAGACGGTTGTCAGCTGCACGACGC GCTGGAACTTGCTGCGCCAACTGCCAAACCACCACAACAACATTGTGGCGGCGTAATGCAAATGGCGATCCCGTGTGTAATGC TTGCGGTCTGTATTATAAATTGCATAACGTGAATAGACCCCTCACTATGAAGAAAGAGGGCATACAAACCCGCAATCGCAAAA TGTCAAATAAAAGCAAGAAGTCTAAGAAGGGCGCCGAATGTTTTGAAGAATTGTCTAAATGTATGCAAGAAAAGAGCAGCCC ATTTTCCGCCGCCGCACTCGCAGGCCATATGGCCCCAGTAGGTCATCTGCCCCCTTTTAGTCATAGCGGGCATATTTTGCCTACG CCAACACCGATTCATCCTAGCAGCTCACTGTCTTTTGGGCATCCACATCCAAGTTCTATGGTCACGGCTATGGGTTGAggatccatt cgatatcaagcttatcgataatcaacctctggattacaaaatttgtgaaagattgactggtattcttaactatgttgctccttttacgctatgtggatacgctgctttaatg cctttgtatcatgctattgcttcccgtatggctttcattttctcctccttgtataaatcctggttgctgtctctttatgaggagttgtggcccgttgtcaggcaacgtggcgtg gtgtgcactgtgtttgctgacgcaacccccactggttggggcattgccaccacctgtcagctcctttccgggactttcgctttccccctccctattgccacggcggaactc atcgccgcctgccttgcccgctgctggacaggggctcggctgttgggcactgacaattccgtggtgttgtcggggaaatcatcgtcctttccttggctgctcgcctgtgtt gccacctggattctgcgcgggacgtccttctgctacgtcccttcggccctcaatccagcggaccttccttcccgcggcctgctgccggctctgcggcctcttccgcgtcttc gccttcgccctcagacgagtcggatctccctttgggccgcctccccgcatcgataccgtcgacctcgagacctagaaaaacatggagcaatcacaagtagcaatacag cagctaccaatgctgattgtgcctggctagaagcacaagaggaggaggaggtgggttttccagtcacacctcaggtacctttaagaccaatgacttacaaggcagctg tagatcttagccactttttaaaagaaaaggggggactggaagggctaattcactcccaacgaagacaagatatccttgatctgtggatctaccacacacaaggctact tccctgattggcagaactacacaccagggccagggatcagatatccactgacctttggatggtgctacaagctagtaccagttgagcaagagaaggtagaagaagcc aatgaaggagagaacacccgcttgttacaccctgtgagcctgcatgggatggatgacccggagagagaagtattagagtggaggtttgacagccgcctagcatttca tcacatggcccgagagctgcatccggactgtactgggtctctctggttagaccagatctgagcctgggagctctctggctaactagggaacccactgcttaagcctcaa taaagcttgccttgagtgcttcaagtagtgtgtgcccgtctgttgtgtgactctggtaactagagatccctcagacccttttagtcagtgtggaaaatctctagcagggcc cgtttaaacccgctgatcagcctcgactgtgccttctagttgccagccatctgttgtttgcccctcccccgtgccttccttgaccctggaaggtgccactcccactgtccttt cctaataaaatgaggaaattgcatcgcattgtctgagtaggtgtcattctattctggggggggggtggggcaggacagcaagggggaggattgggaagacaatagc aggcatgtgagcaaaaggccagcaaaaggccaggaaccgtaaaaaggccgcgttgctggcgtttttccataggctccgcccccctgacgagcatcacaaaaatcga cgctcaagtcagaggtggcgaaacccgacaggactataaagataccaggcgtttccccctggaagctccctcgtgcgctctcctgttccgaccctgccgcttaccggat acctgtccgcctttctcccttcgggaagcgtggcgctttctcatagctcacgctgtaggtatctcagttcggtgtaggtcgttcgctccaagctgggctgtgtgcacgaac cccccgttcagcccgaccgctgcgccttatccggtaactatcgtcttgagtccaacccggtaagacacgacttatcgccactggcagcagccactggtaacaggattag cagagcgaggtatgtaggcggtgctacagagttcttgaagtggtggcctaactacggctacactagaagaacagtatttggtatctgcgctctgctgaagccagttacc ttcggaaaaagagttggtagctcttgatccggcaaacaaaccaccgctggtagcggtggtttttttgtttgcaagcagcagattacgcgcagaaaaaaaggatctcaa gaagatcctttgatcttttctacggggtctgacgctcagtggaacgaaaactcacgttaagggattttggtcatgagattatcaaaaaggatcttcacctagatcctttta aattaaaaatgaagttttaaatcaatctaaagtatatatgagtaaacttggtctgacagttaccaatgcttaatcagtgaggcacctatctcagcgatctgtctatttcgt tcatccatagttgcctgactccccgtcgtgtagataactacgatacgggagggcttaccatctggccccagtgctgcaatgataccgcgagacccacgctcaccggctc cagatttatcagcaataaaccagccagccggaagggccgagcgcagaagtggtcctgcaactttatccgcctccatccagtctattaattgttgccgggaagctagag taagtagttcgccagttaatagtttgcgcaacgttgttgccattgctacaggcatcgtggtgtcacgctcgtcgtttggtatggcttcattcagctccggttcccaacgatc aaggcgagttacatgatcccccatgttgtgcaaaaaagcggttagctccttcggtcctccgatcgttgtcagaagtaagttggccgcagtgttatcactcatggttatgg cagcactgcataattctcttactgtcatgccatccgtaagatgcttttctgtgactggtgagtactcaaccaagtcattctgagaatagtgtatgcggcgaccgagttgct cttgcccggcgtcaatacgggataataccgcgccacatagcagaactttaaaagtgctcatcattggaaaacgttcttcggggcgaaaactctcaaggatcttaccgc tgttgagatccagttcgatgtaacccactcgtgcacccaactgatcttcagcatcttttactttcaccagcgtttctgggtgagcaaaaacaggaaggcaaaatgccgc aaaaaagggaataagggcgacacggaaatgttgaatactcatactcttcctttttcaatattattgaagcatttatcagggttattgtctcatgagcggatacatatttg aatgtatttagaaaaataaacaaataggggttccgcgcacatttccccgaaaagtgccacctgacg SEQIDNo.24-FUW-FoGaGi(vector5) tcgacggatcgggagatctcccgatcccctatggtgcactctcagtacaatctgctctgatgccgcatagttaagccagtatctgctccctgcttgtgtgttggaggtcgc tgagtagtgcgcgagcaaaatttaagctacaacaaggcaaggcttgaccgacaattgcatgaagaatctgcttagggttaggcgttttgcgctgcttcgcgatgtacg ggccagatatacgcgttgacattgattattgactagttattaatagtaatcaattacggggtcattagttcatagcccatatatggagttccgcgttacataacttacggt aaatggcccgcctggctgaccgcccaacgacccccgcccattgacgtcaataatgacgtatgttcccatagtaacgccaatagggactttccattgacgtcaatgggt ggagtatttacggtaaactgcccacttggcagtacatcaagtgtatcatatgccaagtacgccccctattgacgtcaatgacggtaaatggcccgcctggcattatgcc cagtacatgaccttatgggactttcctacttggcagtacatctacgtattagtcatcgctattaccatggtgatgcggttttggcagtacatcaatgggcgtggatagcgg tttgactcacggggatttccaagtctccaccccattgacgtcaatgggagtttgttttggcaccaaaatcaacgggactttccaaaatgtcgtaacaactccgccccatt gacgcaaatgggcggtaggcgtgtacggtgggaggtctatataagcagcgcgttttgcctgtactgggtctctctggttagaccagatctgagcctgggagctctctgg ctaactagggaacccactgcttaagcctcaataaagcttgccttgagtgcttcaagtagtgtgtgcccgtctgttgtgtgactctggtaactagagatccctcagaccctt ttagtcagtgtggaaaatctctagcagtggcgcccgaacagggacttgaaagcgaaagggaaaccagaggagctctctcgacgcaggactcggcttgctgaagcgc gcacggcaagaggcgaggggcggcgactggtgagtacgccaaaaattttgactagcggaggctagaaggagagagatgggtgcgagagcgtcagtattaagcgg gggagaattagatcgcgatgggaaaaaattcggttaaggccagggggaaagaaaaaatataaattaaaacatatagtatgggcaagcagggagctagaacgattc gcagttaatcctggcctgttagaaacatcagaaggctgtagacaaatactgggacagctacaaccatcccttcagacaggatcagaagaacttagatcattatataat acagtagcaaccctctattgtgtgcatcaaaggatagagataaaagacaccaaggaagctttagacaagatagaggaagagcaaaacaaaagtaagaccaccgc acagcaagcggccgctgatcttcagacctggaggaggagatatgagggacaattggagaagtgaattatataaatataaagtagtaaaaattgaaccattaggagt agcacccaccaaggcaaagagaagagtggtgcagagagaaaaaagagcagtgggaataggagctttgttccttgggttcttgggagcagcaggaagcactatggg cgcagcgtcaatgacgctgacggtacaggccagacaattattgtctggtatagtgcagcagcagaacaatttgctgagggctattgaggcgcaacagcatctgttgca actcacagtctggggcatcaagcagctccaggcaagaatcctggctgtggaaagatacctaaaggatcaacagctcctggggatttggggttgctctggaaaactcat ttgcaccactgctgtgccttggaatgctagttggagtaataaatctctggaacagatttggaatcacacgacctggatggagtgggacagagaaattaacaattacac aagcttaatacactccttaattgaagaatcgcaaaaccagcaagaaaagaatgaacaagaattattggaattagataaatgggcaagtttgtggaattggtttaaca taacaaattggctgtggtatataaaattattcataatgatagtaggaggcttggtaggtttaagaatagtttttgctgtactttctatagtgaatagagttaggcagggat attcaccattatcgtttcagacccacctcccaaccccgaggggacccgacaggcccgaaggaatagaagaagaaggtggagagagagacagagacagatccattc gattagtgaacggatcggcactgcgtgcgccaattctgcagacaaatggcagtattcatccacaattttaaaagaaaaggggggattggggggtacagtgcagggg aaagaatagtagacataatagcaacagacatacaaactaaagaattacaaaaacaaattacaaaaattcaaaattttcgggtttattacagggacagcagagatcc agtttggttaattaacccgtgtcggctccagatctggcctccgcgccgggttttggcgcctcccgcgggcgcccccctcctcacggcgagcgctgccacgtcagacgaa gggcgcagcgagcgtcctgatccttccgcccggacgctcaggacagcggcccgctgctcataagactcggccttagaaccccagtatcagcagaaggacattttagg acgggacttgggtgactctagggcactggttttctttccagagagcggaacaggcgaggaaaagtagtcccttctcggcgattctgcggagggatctccgtggggcgg tgaacgccgatgattatataaggacgcgccgggtgtggcacagctagttccgtcgcagccgggatttgggtcgcggttcttgtttgtggatcgctgtgatcgtcacttgg tgagtagcgggctgctgggctggccggggctttcgtggccgccgggccgctcggtgggacggaagcgtgtggagagaccgccaagggctgtagtctgggtccgcgag caaggttgccctgaactgggggttggggggagcgcagcaaaatggcggctgttcccgagtcttgaatggaagacgcttgtgaggcgggctgtgaggtcgttgaaaca aggtggggggcatggtgggcggcaagaacccaaggtcttgaggccttcgctaatgcgggaaagctcttattcgggtgagatgggctggggcaccatctggggaccct gacgtgaagtttgtcactgactggagaactcggtttgtcgtctgttgcgggggcggcagttatggcggtgccgttgggcagtgcacccgtacctttgggagcgcgcgcc ctcgtcgtgtcgtgacgtcacccgttctgttggcttataatgcagggtggggccacctgccggtaggtgtgcggtaggcttttctccgtcgcaggacgcagggttcgggc ctagggtaggctctcctgaatcgacaggcgccggacctctggtgaggggagggataagtgaggcgtcagtttctttggtcggttttatgtacctatcttcttaagtagct gaagctccggttttgaactatgcgctcggggttggcgagtgtgttttgtgaagttttttaggcaccttttgaaatgtaatcatttgggtcaatatgtaattttcagtgttaga ctagtaaattgtccgctaaattctggccgtttttggcttttttgttagacgaagcttgggcccgggatccATGATGTTTTCAGGATTTAATGCTGATTATGA AGCCAGCTCTAGTAGGTGTTCCTCTGCAAGCCCAGCTGGTGACTCCCTGTCATATTATCATAGTCCTGCTGATAGCTTTAGTTCT ATGGGATCTCCAGTGAATGCCCAAGACTTTTGTACAGATCTCGCAGTAAGCAGCGCAAATTTTATCCCGACTGTTACCGCTATT TCCACTTCACCCGATCTCCAATGGCTTGTCCAACCAGCGCTGGTGAGTAGTGTTGCTCCGAGCCAAACACGGGCTCCCCATCCC TTTGGGGTGCCTGCTCCGAGCGCAGGCGCATATAGCCGTGCCGGAGTGGTGAAAACAATGACCGGCGGACGGGCACAATCTA TCGGGCGTAGAGGTAAAGTCGAGCAACTGAGTCCTGAGGAAGAGGAAAAGAGACGGATTAGGGGGAGCGCAACAAAATG GCAGCCGCAAAGTGTCGAAATAGAAGACGCGAACTCACGGACACCCTGCAGGCAGAAACTGATCAGCTTGAGGACGAAAAG AGTGCCCTGCAAACTGAAATCGCAAATCTTCTCAAAGAAAAGGAGAAGCTGGAATTTATTCTCGCCGCACATAGGCCCGCTTG TAAAATTCCCGACGATCTCGGATTTCCTGAGGAAATGAGCGTTGCCTCACTGGACCTTACAGGCGGGTTGCCCGAAGTGGCTA CTCCCGAATCAGAAGAAGCATTTACTCTTCCCCTGCTGAACGATCCCGAACCAAAACCATCCGTTGAGCCGGTGAAATCTATTA GTTCAATGGAATTGAAAACTGAACCTTTCGACGATTTTCTCTTTCCTGCCTCTAGCCGACCATCAGGGTCCGAAACGGCTCGTA GTGTACCTGATATGGATCTGAGCGGTAGCTTTTACGCCGCCGATTGGGAACCTCTCCATTCCGGTTCATTGGGCATGGGACCG ATGGCTACTGAATTGGAACCGCTCTGTACCCCAGTAGTGACATGCACACCTTCATGTACAGCATATACATCAAGCTTTGTGTTT ACTTATCCGGAAGCCGATTCTTTTCCTTCTTGCGCTGCCGCTCATAGGAAAGGCTCCTCTTCTAACGAACCAAGTAGTGATTCAC TGTCATCCCCTACACTTTTGGCTCTTGGCAGCGGCGCCACAAACTTCTCTCTGCTAAAGCAAGCAGGTGATGTTGAAGAAAACC CCGGGCCTATGGAAGTAGCCCCTGAACAACCCAGATGGATGGCTCATCCAGCAGTATTGAACGCACAACATCCAGATTCCCAT CATCCAGGATTGGCCCATAATTATATGGAGCCAGCCCAACTCTTGCCACCTGATGAAGTCGATGTTTTCTTTAACCATCTGGATA GTCAAGGTAATCCTTATTACGCTAATCCAGCACATGCACGCGCTCGGGTTTCATATTCCCCTGCCCATGCAAGGCTTACAGGCG GACAAATGTGTCGTCCTCATCTGCTCCATTCCCCAGGCCTTCCATGGCTTGATGGCGGGAAGGCGGCGCTTTCAGCGGCGGCT GCACATCATCATAATCCGTGGACTGTCTCTCCTTTTAGTAAAACTCCGCTTCATCCGAGCGCAGCAGGCGGACCTGGCGGACCC CTGTCAGTCTATCCTGGTGCCGGTGGCGGCTCCGGCGGTGGGTCCGGTTCCAGCGTTGCAAGCTTGACACCAACGGCGGCTCA TTCAGGATCACATTTGTTTGGTTTTCCCCCAACCCCGCCGAAAGAGGTCAGTCCCGATCCAAGTACAACCGGAGCAGCAAGTCC CGCAAGCTCATCTGCCGGCGGCTCCGCCGCTAGAGGCGAAGATAAAGATGGGGTAAAATATCAAGTCTCTCTTACCGAATCCA TGAAAATGGAGTCTGGATCTCCTCTCCGGCCCGGGCTCGCGACCATGGGGACACAACCCGCAACCCATCATCCAATTCCAACTT ATCCAAGCTACGTTCCCGCTGCAGCACATGATTATTCATCTGGGCTGTTTCATCCGGGCGGATTTCTCGGTGGCCCAGCATCTTC TTTTACTCCCAAACAACGGTCTAAAGCAAGGTCTTGCAGTGAGGGTAGGGAATGCGTGAATTGCGGAGCTACTGCAACTCCCC TGTGGCGTCGCGATGGGACAGGTCATTATCTTTGTAACGCTTGCGGACTTTATCATAAAATGAACGGCCAAAATCGCCCGCTG ATTAAACCTAAACGCAGGTTGTCAGCGGCTCGCAGGGGGGGGACATGCTGCGCCAACTGCCAAACCACCACTACAACACTGTG GCGAAGAAATGCAAATGGCGATCCCGTGTGTAATGCTTGCGGGCTTTATTATAAACTCCATAACGTCAATCGGCCTCTTACAAT GAAGAAAGAGGGAATTCAAACCAGGAATAGGAAAATGTCAAATAAAAGCAAGAAATCAAAGAAGGGCGCCGAATGTTTTGA AGAATTGTCTAAATGTATGCAAGAGAAATCTTCACCGTTTTCCGCCGCCGCGTTGGCCGGTCATATGGCTCCAGTCGGACATCT TCCGCCATTTTCACATAGTGGGCATATTCTTCCAACACCCACACCTATTCATCCTTCATCTTCTCTGTCATTTGGACATCCTCATCC TAGCTCCATGGTTACTGCAATGGGCGGCTCCGGCGAGGGCAGGGGAAGTCTTCTAACATGCGGGGACGTGGAGGAAAATCC CGGCCCAATGCCCCGAAGTTTTCTCGTTAAATCAAAGAAAGCACATACTTATCATCAACCTCGCGTCCAAGAGGACGAGCCACT TTGGCCACCCGCTCTGACACCTGTCCCGAGGGATCAAGCGCCGTCCAATTCACCCGTGTTGTCTACCCTCTTTCCCAATCAATGT TTGGATTGGACAAATTTGAAGAGGGAACCAGAACTTGAACAAGATCAAAATCTTGCGCGGATGGCGCCTGCCCCGGAAGGGC CAATCGTCCTCAGCCGGCCGCAAGACGGCGATTCCCCTCTTAGCGATAGCCCACCATTTTATAAACCCAGTTTTAGCTGGGATA CTCTGGCTACTACTTACGGACATTCATATAGACAAGCGCCTTCAACGATGCAAAGCGCATTTCTTGAACATAGTGTGTCCCTTTA TGGTTCCCCACTCGTTCCTTCCACAGAACCAGCTCTGGATTTCTCACTTCGATATTCTCCCGGGATGGACGCTTATCATTGCGTA AAATGTAATAAAGTGTTTTCTACACCGCATGGTCTGGAAGTCCACGTACGCCGTAGTCACTCCGGCACAAGGCCTTTTGCGTGC GATATTTGTGGGAAGACGTTTGGTCATGCCGTATCACTCGAACAACATACACATGTGCATTCTCAAGAACGGAGTTTTGAATGT AGAATGTGTGGTAAAGCTTTTAAAAGGTCATCAACTTTGAGTACTCATCTCTTGATACACAGCGATACAAGGCCGTATCCATGT CAATTTTGTGGAAAACGGTTTCATCAAAAGTCAGATATGAAGAAACATACATATATTCATACCGGGGAAAAGCCCCATAAATG TCAAGTCTGTGGTAAAGCGTTTTCTCAATCTAGTAATCTGATTACACATTCTCGTAAACATACTGGGTTTAAACCTTTCTCTTGCG AACTTTGTACAAAGGGATTTCAACGGAAAGTCGATCTTCGTAGACATAGAGAATCCCAACATAACCTTAAATAAggatccattcgat atcaagcttatcgataatcaacctctggattacaaaatttgtgaaagattgactggtattcttaactatgttgctccttttacgctatgtggatacgctgctttaatgccttt gtatcatgctattgcttcccgtatggctttcattttctcctccttgtataaatcctggttgctgtctctttatgaggagttgtggcccgttgtcaggcaacgtggcgtggtgtg cactgtgtttgctgacgcaacccccactggttggggcattgccaccacctgtcagctcctttccgggactttcgctttccccctccctattgccacggcggaactcatcgc cgcctgccttgcccgctgctggacaggggctcggctgttgggcactgacaattccgtggtgttgtcggggaaatcatcgtcctttccttggctgctcgcctgtgttgccac ctggattctgcgcgggacgtccttctgctacgtcccttcggccctcaatccagcggaccttccttcccgcggcctgctgccggctctgcggcctcttccgcgtcttcgcctt cgccctcagacgagtcggatctccctttgggccgcctccccgcatcgataccgtcgacctcgagacctagaaaaacatggagcaatcacaagtagcaatacagcagc taccaatgctgattgtgcctggctagaagcacaagaggaggaggaggtgggttttccagtcacacctcaggtacctttaagaccaatgacttacaaggcagctgtaga tcttagccactttttaaaagaaaaggggggactggaagggctaattcactcccaacgaagacaagatatccttgatctgtggatctaccacacacaaggctacttccct gattggcagaactacacaccagggccagggatcagatatccactgacctttggatggtgctacaagctagtaccagttgagcaagagaaggtagaagaagccaatg aaggagagaacacccgcttgttacaccctgtgagcctgcatgggatggatgacccggagagagaagtattagagtggaggtttgacagccgcctagcatttcatcac atggcccgagagctgcatccggactgtactgggtctctctggttagaccagatctgagcctgggagctctctggctaactagggaacccactgcttaagcctcaataaa gcttgccttgagtgcttcaagtagtgtgtgcccgtctgttgtgtgactctggtaactagagatccctcagacccttttagtcagtgtggaaaatctctagcagggcccgttt aaacccgctgatcagcctcgactgtgccttctagttgccagccatctgttgtttgcccctcccccgtgccttccttgaccctggaaggtgccactcccactgtcctttccta ataaaatgaggaaattgcatcgcattgtctgagtaggtgtcattctattctggggggtggggtggggcaggacagcaagggggaggattgggaagacaatagcagg catgtgagcaaaaggccagcaaaaggccaggaaccgtaaaaaggccgcgttgctggcgtttttccataggctccgcccccctgacgagcatcacaaaaatcgacgc tcaagtcagaggtggcgaaacccgacaggactataaagataccaggcgtttccccctggaagctccctcgtgcgctctcctgttccgaccctgccgcttaccggatacc tgtccgcctttctcccttcgggaagcgtggcgctttctcatagctcacgctgtaggtatctcagttcggtgtaggtcgttcgctccaagctgggctgtgtgcacgaacccc ccgttcagcccgaccgctgcgccttatccggtaactatcgtcttgagtccaacccggtaagacacgacttatcgccactggcagcagccactggtaacaggattagca gagcgaggtatgtaggcggtgctacagagttcttgaagtggtggcctaactacggctacactagaagaacagtatttggtatctgcgctctgctgaagccagttacctt cggaaaaagagttggtagctcttgatccggcaaacaaaccaccgctggtagcggtggtttttttgtttgcaagcagcagattacgcgcagaaaaaaaggatctcaag aagatcctttgatcttttctacggggtctgacgctcagtggaacgaaaactcacgttaagggattttggtcatgagattatcaaaaaggatcttcacctagatccttttaa attaaaaatgaagttttaaatcaatctaaagtatatatgagtaaacttggtctgacagttaccaatgcttaatcagtgaggcacctatctcagcgatctgtctatttcgtt catccatagttgcctgactccccgtcgtgtagataactacgatacgggagggcttaccatctggccccagtgctgcaatgataccgcgagacccacgctcaccggctcc agatttatcagcaataaaccagccagccggaagggccgagcgcagaagtggtcctgcaactttatccgcctccatccagtctattaattgttgccgggaagctagagt aagtagttcgccagttaatagtttgcgcaacgttgttgccattgctacaggcatcgtggtgtcacgctcgtcgtttggtatggcttcattcagctccggttcccaacgatc aaggcgagttacatgatcccccatgttgtgcaaaaaagcggttagctccttcggtcctccgatcgttgtcagaagtaagttggccgcagtgttatcactcatggttatgg cagcactgcataattctcttactgtcatgccatccgtaagatgcttttctgtgactggtgagtactcaaccaagtcattctgagaatagtgtatgcggcgaccgagttgct cttgcccggcgtcaatacgggataataccgcgccacatagcagaactttaaaagtgctcatcattggaaaacgttcttcggggcgaaaactctcaaggatcttaccgc tgttgagatccagttcgatgtaacccactcgtgcacccaactgatcttcagcatcttttactttcaccagcgtttctgggtgagcaaaaacaggaaggcaaaatgccgc aaaaaagggaataagggcgacacggaaatgttgaatactcatactcttcctttttcaatattattgaagcatttatcagggttattgtctcatgagcggatacatatttg aatgtatttagaaaaataaacaaataggggttccgcgcacatttccccgaaaagtgccacctgacg SEQIDNo.25-FUW-FoGiGa(vector6) tcgacggatcgggagatctcccgatcccctatggtgcactctcagtacaatctgctctgatgccgcatagttaagccagtatctgctccctgcttgtgtgttggaggtcgc tgagtagtgcgcgagcaaaatttaagctacaacaaggcaaggcttgaccgacaattgcatgaagaatctgcttagggttaggcgttttgcgctgcttcgcgatgtacg ggccagatatacgcgttgacattgattattgactagttattaatagtaatcaattacggggtcattagttcatagcccatatatggagttccgcgttacataacttacggt aaatggcccgcctggctgaccgcccaacgacccccgcccattgacgtcaataatgacgtatgttcccatagtaacgccaatagggactttccattgacgtcaatgggt ggagtatttacggtaaactgcccacttggcagtacatcaagtgtatcatatgccaagtacgccccctattgacgtcaatgacggtaaatggcccgcctggcattatgcc cagtacatgaccttatgggactttcctacttggcagtacatctacgtattagtcatcgctattaccatggtgatgcggttttggcagtacatcaatgggcgtggatagcgg tttgactcacggggatttccaagtctccaccccattgacgtcaatgggagtttgttttggcaccaaaatcaacgggactttccaaaatgtcgtaacaactccgccccatt gacgcaaatgggcggtaggcgtgtacggtgggaggtctatataagcagcgcgttttgcctgtactgggtctctctggttagaccagatctgagcctgggagctctctgg ctaactagggaacccactgcttaagcctcaataaagcttgccttgagtgcttcaagtagtgtgtgcccgtctgttgtgtgactctggtaactagagatccctcagaccctt ttagtcagtgtggaaaatctctagcagtggcgcccgaacagggacttgaaagcgaaagggaaaccagaggagctctctcgacgcaggactcggcttgctgaagcgc gcacggcaagaggcgaggggcggcgactggtgagtacgccaaaaattttgactagcggaggctagaaggagagagatgggtgcgagagcgtcagtattaagcgg gggagaattagatcgcgatgggaaaaaattcggttaaggccagggggaaagaaaaaatataaattaaaacatatagtatgggcaagcagggagctagaacgattc gcagttaatcctggcctgttagaaacatcagaaggctgtagacaaatactgggacagctacaaccatcccttcagacaggatcagaagaacttagatcattatataat acagtagcaaccctctattgtgtgcatcaaaggatagagataaaagacaccaaggaagctttagacaagatagaggaagagcaaaacaaaagtaagaccaccgc acagcaagcggccgctgatcttcagacctggaggaggagatatgagggacaattggagaagtgaattatataaatataaagtagtaaaaattgaaccattaggagt agcacccaccaaggcaaagagaagagtggtgcagagagaaaaaagagcagtgggaataggagctttgttccttgggttcttgggagcagcaggaagcactatggg cgcagcgtcaatgacgctgacggtacaggccagacaattattgtctggtatagtgcagcagcagaacaatttgctgagggctattgaggcgcaacagcatctgttgca actcacagtctggggcatcaagcagctccaggcaagaatcctggctgtggaaagatacctaaaggatcaacagctcctggggatttggggttgctctggaaaactcat ttgcaccactgctgtgccttggaatgctagttggagtaataaatctctggaacagatttggaatcacacgacctggatggagtgggacagagaaattaacaattacac aagcttaatacactccttaattgaagaatcgcaaaaccagcaagaaaagaatgaacaagaattattggaattagataaatgggcaagtttgtggaattggtttaaca taacaaattggctgtggtatataaaattattcataatgatagtaggaggcttggtaggtttaagaatagtttttgctgtactttctatagtgaatagagttaggcagggat attcaccattatcgtttcagacccacctcccaaccccgaggggacccgacaggcccgaaggaatagaagaagaaggtggagagagagacagagacagatccattc gattagtgaacggatcggcactgcgtgcgccaattctgcagacaaatggcagtattcatccacaattttaaaagaaaaggggggattggggggtacagtgcagggg aaagaatagtagacataatagcaacagacatacaaactaaagaattacaaaaacaaattacaaaaattcaaaattttcgggtttattacagggacagcagagatcc agtttggttaattaacccgtgtcggctccagatctggcctccgcgccgggttttggcgcctcccgcgggcgcccccctcctcacggcgagcgctgccacgtcagacgaa gggcgcagcgagcgtcctgatccttccgcccggacgctcaggacagcggcccgctgctcataagactcggccttagaaccccagtatcagcagaaggacattttagg acgggacttgggtgactctagggcactggttttctttccagagagcggaacaggcgaggaaaagtagtcccttctcggcgattctgcggagggatctccgtggggcgg tgaacgccgatgattatataaggacgcgccgggtgtggcacagctagttccgtcgcagccgggatttgggtcgcggttcttgtttgtggatcgctgtgatcgtcacttgg tgagtagcgggctgctgggctggccggggctttcgtggccgccgggccgctcggtgggacggaagcgtgtggagagaccgccaagggctgtagtctgggtccgcgag caaggttgccctgaactgggggttggggggagcgcagcaaaatggcggctgttcccgagtcttgaatggaagacgcttgtgaggcgggctgtgaggtcgttgaaaca aggtggggggcatggtgggcggcaagaacccaaggtcttgaggccttcgctaatgcgggaaagctcttattcgggtgagatgggctggggcaccatctggggaccct gacgtgaagtttgtcactgactggagaactcggtttgtcgtctgttgcgggggcggcagttatggcggtgccgttgggcagtgcacccgtacctttgggagcgcgcgcc ctcgtcgtgtcgtgacgtcacccgttctgttggcttataatgcagggtggggccacctgccggtaggtgtgcggtaggcttttctccgtcgcaggacgcagggttcgggc ctagggtaggctctcctgaatcgacaggcgccggacctctggtgaggggagggataagtgaggcgtcagtttctttggtcggttttatgtacctatcttcttaagtagct gaagctccggttttgaactatgcgctcggggttggcgagtgtgttttgtgaagttttttaggcaccttttgaaatgtaatcatttgggtcaatatgtaattttcagtgttaga ctagtaaattgtccgctaaattctggccgtttttggcttttttgttagacgaagcttgggcccgggatccATGATGTTTAGCGGATTTAATGCCGATTATGA AGCAAGCTCATCTCGATGTTCATCTGCAAGCCCAGCTGGTGACTCACTGAGCTATTATCATAGCCCGGCTGATTCATTTTCATCT ATGGGTTCCCCCGTTAATGCCCAAGACTTTTGTACCGATCTCGCAGTGAGCAGCGCAAATTTTATCCCTACCGTGACCGCTATAT CAACTAGCCCCGATTTGCAATGGCTTGTCCAACCAGCGTTGGTGTCAAGCGTTGCACCCAGCCAAACTCGCGCTCCCCATCCCT TTGGCGTGCCAGCTCCGAGCGCAGGCGCCTATTCACGGGCAGGGGTAGTCAAAACAATGACCGGCGGACGCGCTCAATCCAT CGGAAGAAGAGGGAAAGTCGAGCAACTCTCCCCCGAGGAAGAGGAAAAGCGACGCATTAGAAGAGAGCGGAACAAAATGG CCGCCGCTAAGTGTCGGAATAGACGCCGCGAACTCACCGACACTCTGCAGGCCGAAACCGATCAGCTGGAAGACGAAAAGAG TGCCCTTCAAACTGAAATCGCAAATCTCTTGAAAGAAAAGGAGAAGCTGGAATTTATTCTTGCTGCACATCGTCCAGCATGTAA AATTCCGGACGATTTGGGGTTTCCCGAGGAAATGTCCGTTGCCTCTCTCGACTTGACCGGTGGGTTGCCTGAAGTAGCTACACC CGAAAGTGAAGAAGCGTTTACTCTTCCATTGCTTAACGATCCAGAACCAAAACCAAGCGTTGAGCCCGTAAAATCTATTTCTTC AATGGAACTCAAAACTGAACCATTCGACGATTTTCTCTTTCCTGCTTCTAGTAGACCATCTGGCTCCGAAACCGCACGATCTGTA CCTGATATGGATCTGTCCGGAAGCTTTTACGCCGCCGATTGGGAACCACTCCATTCCGGTTCACTCGGAATGGGACCTATGGCT ACGGAATTGGAACCTCTTTGTACCCCAGTTGTAACTTGCACCCCATCATGTACCGCCTATACCTCTAGCTTTGTATTTACGTATCC TGAAGCCGATAGCTTTCCATCTTGCGCCGCCGCGCATAGGAAAGGATCTTCAAGTAACGAACCCAGTTCCGATAGTTTGAGTTC TCCGACACTTCTCGCTCTTGGCAGCGGCGCCACAAACTTCTCTCTGCTAAAGCAAGCAGGTGATGTTGAAGAAAACCCCGGGC CTATGCCCCGTTCTTTCTTGGTAAAATCCAAGAAGGCGCATACATATCATCAACCACGGGTTCAAGAGGACGAGCCACTGTGG CCGCCAGCTCTGACTCCCGTCCCTCGGGATCAAGCCCCCTCTAATTCTCCCGTGCTGTCAACATTGTTTCCTAATCAATGTTTGG ATTGGACTAATCTGAAGCGCGAACCAGAATTGGAACAAGATCAAAATCTCGCTCGGATGGCTCCTGCTCCGGAAGGTCCTATC GTTCTTTCAAGACCACAAGACGGCGATTCACCCCTCTCAGATTCTCCCCCTTTCTATAAACCCAGCTTTAGTTGGGATACTCTGG CAACCACATACGGGCATTCTTATCGCCAAGCGCCAAGCACAATGCAAAGTGCATTTCTCGAACATTCAGTATCTCTTTATGGAT CTCCCCTGGTCCCTTCTACCGAACCAGCGCTTGACTTTTCCTTGAGGTATAGTCCCGGGATGGACGCATATCATTGCGTAAAAT GTAATAAAGTTTTCAGCACGCCCCATGGATTGGAAGTCCACGTCAGGCGATCTCACTCTGGCACAAGACCTTTTGCATGCGATA TTTGTGGTAAGACGTTTGGACATGCCGTTTCACTCGAACAACATACACATGTTCATAGCCAAGAACGTTCATTTGAATGTAGAA TGTGTGGAAAAGCATTTAAAAGGAGCTCTACCCTTTCTACACATTTGCTGATTCATAGCGATACCCGACCTTATCCGTGTCAATT TTGTGGAAAACGATTTCATCAGAAATCAGATATGAAGAAGCATACATATATACATACCGGGGAGAAACCCCATAAATGTCAAG TCTGTGGCAAAGCATTTTCTCAATCAAGCAATCTGATTACTCATTCCAGAAAACATACTGGATTTAAACCCTTTTCATGCGAACT TTGTACTAAGGGATTTCAACGGAAAGTTGATTTGAGGAGACATCGAGAAAGTCAACATAACCTGAAAGGCTCCGGCGAGGGC AGGGGAAGTCTTCTAACATGCGGGGACGTGGAGGAAAATCCCGGCCCAATGGAAGTTGCCCCGGAACAACCCCGTTGGATG GCCCATCCTGCAGTACTTAACGCCCAACATCCGGATTCCCATCATCCCGGACTCGCTCATAATTATATGGAGCCGGCTCAACTCT TGCCACCCGATGAAGTCGATGTGTTCTTTAACCATCTGGATTCTCAAGGGAATCCATATTACGCAAATCCAGCACATGCCCGAG CCAGAGTTAGCTATTCACCTGCCCATGCAAGATTGACTGGTGGACAAATGTGTCGGCCCCATCTGCTCCATTCACCAGGGCTCC CATGGCTTGATGGCGGTAAGGCTGCGCTGAGCGCTGCCGCCGCACATCATCATAATCCATGGACAGTATCTCCCTTTTCTAAAA CTCCCCTTCATCCTTCTGCAGCCGGTGGACCCGGCGGACCTTTGAGTGTTTATCCTGGCGCAGGCGGCGGTTCCGGCGGCGGG AGTGGAAGCAGTGTCGCGAGTCTGACGCCCACTGCTGCACATTCAGGAAGTCATCTGTTTGGGTTTCCCCCAACTCCACCCAAA GAGGTTTCCCCAGATCCAAGTACAACCGGCGCAGCCAGTCCCGCTTCCTCTAGCGCCGGCGGCTCAGCTGCTAGAGGGGAAG ATAAAGATGGTGTTAAATATCAAGTTAGCCTTACTGAATCTATGAAAATGGAGTCAGGGAGCCCGCTCAGACCCGGGCTGGCG ACGATGGGTACACAACCGGCCACTCATCATCCTATTCCGACGTATCCGAGTTACGTTCCCGCCGCCGCTCATGATTATTCTTCCG GCCTGTTTCATCCAGGCGGTTTTCTTGGCGGCCCCGCGAGCTCATTTACGCCCAAACAAAGGAGTAAAGCCAGATCTTGCTCTG AGGGGAGAGAATGCGTGAATTGCGGCGCGACGGCAACTCCCTTGTGGCGCCGCGATGGTACTGGGCATTATCTCTGTAACGC ATGCGGATTGTATCATAAAATGAACGGTCAAAATAGGCCTCTGATAAAACCTAAACGGCGCCTTAGTGCGGCAAGGCGTGCA GGAACATGCTGCGCTAACTGCCAAACAACTACAACTACTTTGTGGCGGCGCAATGCGAATGGTGATCCCGTGTGTAATGCTTG CGGATTGTATTATAAACTCCATAACGTGAATCGTCCTCTCACTATGAAGAAGGAAGGAATTCAAACGCGCAATAGGAAAATGT CTAATAAAAGCAAGAAGTCCAAGAAGGGCGCTGAATGTTTTGAAGAACTCAGCAAATGTATGCAAGAGAAATCCAGTCCATTT TCAGCCGCCGCACTTGCAGGTCATATGGCTCCCGTCGGGCATTTGCCACCGTTTTCCCATAGCGGTCATATTCTCCCAACCCCTA CTCCAATACATCCTTCTAGCTCTCTGAGTTTTGGGCATCCTCATCCCAGTTCCATGGTCACAGCGATGGGTTGAggatccattcgatat caagcttatcgataatcaacctctggattacaaaatttgtgaaagattgactggtattcttaactatgttgctccttttacgctatgtggatacgctgctttaatgcctttgt atcatgctattgcttcccgtatggctttcattttctcctccttgtataaatcctggttgctgtctctttatgaggagttgtggcccgttgtcaggcaacgtggcgtggtgtgca ctgtgtttgctgacgcaacccccactggttggggcattgccaccacctgtcagctcctttccgggactttcgctttccccctccctattgccacggcggaactcatcgccg cctgccttgcccgctgctggacaggggctcggctgttgggcactgacaattccgtggtgttgtcggggaaatcatcgtcctttccttggctgctcgcctgtgttgccacct ggattctgcgcgggacgtccttctgctacgtcccttcggccctcaatccagcggaccttccttcccgcggcctgctgccggctctgcggcctcttccgcgtcttcgccttcg ccctcagacgagtcggatctccctttgggccgcctccccgcatcgataccgtcgacctcgagacctagaaaaacatggagcaatcacaagtagcaatacagcagcta ccaatgctgattgtgcctggctagaagcacaagaggaggaggaggtgggttttccagtcacacctcaggtacctttaagaccaatgacttacaaggcagctgtagatc ttagccactttttaaaagaaaaggggggactggaagggctaattcactcccaacgaagacaagatatccttgatctgtggatctaccacacacaaggctacttccctg attggcagaactacacaccagggccagggatcagatatccactgacctttggatggtgctacaagctagtaccagttgagcaagagaaggtagaagaagccaatga aggagagaacacccgcttgttacaccctgtgagcctgcatgggatggatgacccggagagagaagtattagagtggaggtttgacagccgcctagcatttcatcaca tggcccgagagctgcatccggactgtactgggtctctctggttagaccagatctgagcctgggagctctctggctaactagggaacccactgcttaagcctcaataaag cttgccttgagtgcttcaagtagtgtgtgcccgtctgttgtgtgactctggtaactagagatccctcagacccttttagtcagtgtggaaaatctctagcagggcccgttta aacccgctgatcagcctcgactgtgccttctagttgccagccatctgttgtttgcccctcccccgtgccttccttgaccctggaaggtgccactcccactgtcctttcctaat aaaatgaggaaattgcatcgcattgtctgagtaggtgtcattctattctggggggtggggggggcaggacagcaagggggaggattgggaagacaatagcaggca tgtgagcaaaaggccagcaaaaggccaggaaccgtaaaaaggccgcgttgctggcgtttttccataggctccgcccccctgacgagcatcacaaaaatcgacgctc aagtcagaggtggcgaaacccgacaggactataaagataccaggcgtttccccctggaagctccctcgtgcgctctcctgttccgaccctgccgcttaccggatacctg tccgcctttctcccttcgggaagcgtggcgctttctcatagctcacgctgtaggtatctcagttcggtgtaggtcgttcgctccaagctgggctgtgtgcacgaacccccc gttcagcccgaccgctgcgccttatccggtaactatcgtcttgagtccaacccggtaagacacgacttatcgccactggcagcagccactggtaacaggattagcaga gcgaggtatgtaggcggtgctacagagttcttgaagtggtggcctaactacggctacactagaagaacagtatttggtatctgcgctctgctgaagccagttaccttcg gaaaaagagttggtagctcttgatccggcaaacaaaccaccgctggtagcggtggtttttttgtttgcaagcagcagattacgcgcagaaaaaaaggatctcaagaa gatcctttgatcttttctacggggtctgacgctcagtggaacgaaaactcacgttaagggattttggtcatgagattatcaaaaaggatcttcacctagatccttttaaat taaaaatgaagttttaaatcaatctaaagtatatatgagtaaacttggtctgacagttaccaatgcttaatcagtgaggcacctatctcagcgatctgtctatttcgttca tccatagttgcctgactccccgtcgtgtagataactacgatacgggagggcttaccatctggccccagtgctgcaatgataccgcgagacccacgctcaccggctccag atttatcagcaataaaccagccagccggaagggccgagcgcagaagtggtcctgcaactttatccgcctccatccagtctattaattgttgccgggaagctagagtaa gtagttcgccagttaatagtttgcgcaacgttgttgccattgctacaggcatcgtggtgtcacgctcgtcgtttggtatggcttcattcagctccggttcccaacgatcaa ggcgagttacatgatcccccatgttgtgcaaaaaagcggttagctccttcggtcctccgatcgttgtcagaagtaagttggccgcagtgttatcactcatggttatggca gcactgcataattctcttactgtcatgccatccgtaagatgcttttctgtgactggtgagtactcaaccaagtcattctgagaatagtgtatgcggcgaccgagttgctct tgcccggcgtcaatacgggataataccgcgccacatagcagaactttaaaagtgctcatcattggaaaacgttcttcggggcgaaaactctcaaggatcttaccgctg ttgagatccagttcgatgtaacccactcgtgcacccaactgatcttcagcatcttttactttcaccagcgtttctgggtgagcaaaaacaggaaggcaaaatgccgcaa aaaagggaataagggcgacacggaaatgttgaatactcatactcttcctttttcaatattattgaagcatttatcagggttattgtctcatgagcggatacatatttgaat gtatttagaaaaataaacaaataggggttccgcgcacatttccccgaaaagtgccacctgacg SEQIDNo.26-GATA2(fromvector1) ATGGAAGTCGCTCCTGAACAACCACGGTGGATGGCTCATCCTGCAGTTCTTAACGCTCAACATCCAGATAGCCATCATCCTGGG CTCGCTCATAATTATATGGAGCCTGCCCAACTCCTTCCCCCAGATGAAGTAGATGTATTCTTTAACCATCTTGATAGCCAAGGAA ATCCTTATTACGCAAATCCTGCCCATGCCAGAGCCAGAGTAAGCTATTCACCAGCCCATGCAAGGCTTACTGGTGGACAAATGT GTCGGCCCCATCTGCTGCATTCCCCCGGCCTGCCGTGGTTGGATGGCGGAAAGGCGGCTCTGAGTGCGGCGGCTGCACATCAT CATAATCCTTGGACAGTCTCACCTTTCTCTAAAACTCCCCTTCATCCTAGTGCAGCCGGTGGTCCAGGTGGTCCGCTGTCCGTTT ATCCCGGCGCCGGCGGCGGAAGTGGCGGCGGAAGTGGCAGTAGCGTAGCTTCATTGACACCCACAGCTGCTCATTCCGGAAG TCATCTCTTTGGGTTTCCCCCTACCCCGCCGAAAGAGGTTTCCCCAGATCCGTCAACTACCGGTGCCGCTTCCCCTGCTAGTTCC AGTGCCGGCGGAAGCGCTGCAAGGGGCGAAGATAAAGATGGAGTGAAATATCAAGTCTCCTTGACAGAATCCATGAAAATG GAGTCCGGTTCTCCACTCAGGCCTGGACTCGCCACAATGGGTACTCAACCCGCCACCCATCATCCAATACCGACTTATCCTTCAT ACGTACCAGCCGCCGCTCATGATTATTCATCAGGTTTGTTTCATCCAGGTGGATTTCTTGGCGGGCCTGCTAGTTCTTTTACACC AAAACAAAGGTCCAAAGCCAGGTCTTGCAGTGAGGGGCGCGAATGCGTAAATTGCGGCGCTACCGCAACACCACTGTGGCGT CGTGATGGAACAGGACATTATCTTTGTAACGCATGCGGGCTGTATCATAAAATGAACGGACAAAATCGGCCCCTGATTAAACC TAAACGTCGCTTGTCTGCTGCAAGGCGGGCTGGGACGTGCTGCGCCAACTGCCAAACAACCACAACAACACTGTGGCGTAGG AATGCTAATGGCGATCCCGTATGTAATGCATGCGGTCTGTATTATAAACTTCATAACGTCAATCGGCCCCTTACTATGAAGAAA GAGGGCATACAAACCCGAAATCGCAAAATGTCAAATAAATCTAAGAAATCCAAGAAGGGAGCCGAATGTTTTGAAGAACTCA GCAAATGTATGCAAGAAAAGTCCAGCCCGTTTTCCGCCGCCGCTTTGGCCGGCCATATGGCCCCCGTCGGACATCTGCCACCG TTTTCCCATAGCGGTCATATTCTTCCTACACCCACCCCAATTCATCCGTCTAGCTCCCTGTCTTTTGGGCATCCTCATCCTAGCTCA ATGGTCACAGCTATGGGT SEQIDNo.27-GATA2(fromvector2) ATGGAAGTCGCCCCGGAACAACCACGATGGATGGCACATCCTGCAGTTCTCAACGCACAACATCCTGATAGTCATCATCCAGG GTTGGCTCATAATTATATGGAGCCTGCCCAACTCCTTCCCCCTGATGAAGTTGATGTGTTCTTTAACCATCTGGATTCTCAAGGA AATCCGTATTACGCTAATCCAGCCCATGCACGCGCACGTGTTTCATATAGTCCTGCCCATGCGAGGCTTACAGGCGGGCAAAT GTGTCGTCCCCATCTCCTGCATTCTCCCGGCCTGCCGTGGCTTGATGGTGGAAAGGCTGCGCTGAGCGCTGCCGCCGCTCATCA TCATAATCCATGGACTGTCAGTCCGTTTTCTAAAACTCCTTTGCATCCATCTGCAGCCGGTGGACCAGGCGGTCCGCTTTCAGTT TATCCCGGTGCGGGTGGCGGCTCCGGCGGCGGTTCAGGATCAAGCGTCGCGAGCCTGACTCCAACGGCTGCTCATAGTGGTA GCCATCTGTTTGGGTTTCCCCCAACTCCCCCTAAAGAGGTCAGCCCAGATCCAAGCACGACCGGCGCCGCTTCCCCTGCATCCA GCTCTGCCGGTGGGAGCGCGGCAAGAGGGGAAGATAAAGATGGAGTGAAATATCAAGTAAGTTTGACAGAATCAATGAAAA TGGAGAGCGGATCTCCTCTCCGGCCCGGGCTTGCCACAATGGGTACTCAACCAGCCACCCATCATCCTATTCCAACATATCCTA GCTACGTTCCCGCCGCCGCTCATGATTATTCATCTGGTCTGTTTCATCCTGGCGGGTTCTTGGGCGGCCCCGCGAGCAGTTTTA CACCCAAACAACGTTCTAAAGCCAGGAGCTGCAGTGAGGGTAGAGAATGCGTTAATTGCGGCGCTACTGCAACACCGCTTTG GCGAAGAGATGGTACTGGTCATTATTTGTGTAACGCATGCGGTCTGTATCATAAAATGAACGGTCAAAATCGGCCCCTGATTA AACCTAAAAGGCGGCTTAGTGCGGCAAGGCGTGCAGGAACTTGCTGCGCCAACTGCCAAACAACGACAACTACTCTCTGGAG ACGGAATGCAAATGGTGATCCGGTTTGTAATGCGTGCGGGCTGTATTATAAATTGCATAACGTCAATCGGCCGCTTACAATGA AGAAAGAGGGAATACAAACCAGAAATCGCAAAATGAGCAATAAATCTAAGAAATCTAAGAAGGGAGCAGAATGTTTTGAGG AACTCAGCAAATGTATGCAAGAAAAGTCCAGCCCTTTCTCCGCTGCAGCTTTGGCGGGGCATATGGCTCCCGTCGGTCATCTTC CACCGTTTTCTCATAGCGGTCATATTCTTCCTACGCCCACCCCAATACATCCTTCTTCATCTTTGTCATTTGGACATCCTCATCCAT CTTCTATGGTCACTGCAATGGGC SEQIDNo.28-GATA2(fromvector3) ATGGAAGTTGCCCCTGAACAACCAAGATGGATGGCCCATCCCGCGGTCCTCAACGCCCAACATCCAGATTCTCATCATCCCGGT CTTGCCCATAATTATATGGAGCCTGCCCAACTTTTGCCCCCAGATGAAGTAGATGTATTCTTCAACCATCTGGATTCCCAAGGAA ATCCTTATTACGCAAATCCAGCCCATGCACGCGCCAGGGTGAGCTATTCTCCAGCCCATGCAAGGCTTACGGGCGGACAAATG TGTAGACCTCATCTGCTCCATAGTCCAGGCCTGCCATGGCTTGATGGCGGTAAGGCCGCGCTTAGCGCTGCAGCAGCTCATCA TCATAATCCATGGACTGTCTCCCCATTTAGCAAAACACCGCTTCATCCTTCTGCAGCAGGTGGGCCGGGCGGACCTCTGAGCGT ATATCCTGGCGCAGGTGGCGGCTCCGGCGGCGGGTCAGGAAGTAGTGTCGCGAGCCTGACTCCAACCGCTGCTCATAGCGGG AGTCATCTGTTTGGGTTTCCGCCAACACCCCCTAAAGAGGTATCCCCAGATCCATCTACTACCGGTGCCGCCAGTCCCGCAAGC TCCAGTGCAGGCGGCAGCGCTGCTAGAGGTGAAGATAAAGATGGGGTGAAATATCAAGTTTCCCTCACCGAAAGTATGAAAA TGGAGTCCGGAAGCCCACTTCGACCTGGTCTTGCCACCATGGGAACACAACCCGCCACCCATCATCCTATACCAACGTATCCAA GCTACGTCCCCGCTGCAGCTCATGATTATTCATCAGGGCTGTTTCATCCTGGTGGATTCTTGGGCGGTCCTGCTTCAAGTTTTAC TCCGAAACAACGGTCTAAAGCCAGGAGCTGCTCCGAGGGAAGGGAATGCGTGAATTGCGGAGCAACCGCTACTCCCCTTTGG CGAAGGGATGGTACTGGTCATTATCTTTGTAACGCATGCGGGCTGTATCATAAAATGAACGGCCAAAATCGGCCCCTGATTAA ACCAAAACGGAGACTTTCCGCTGCACGGCGTGCTGGGACATGCTGCGCTAACTGCCAAACCACCACTACAACTCTCTGGCGGC GGAATGCTAATGGTGATCCAGTGTGTAATGCTTGCGGGCTGTATTACAAACTTCATAACGTGAATCGCCCTCTTACGATGAAG AAAGAGGGAATTCAAACGCGTAATCGTAAAATGTCAAATAAATCAAAGAAATCTAAGAAGGGTGCTGAATGTTTTGAGGAAC TCAGCAAATGTATGCAAGAGAAAAGCAGCCCTTTTAGCGCGGCGGCGCTTGCAGGGCATATGGCCCCAGTAGGTCATCTGCCC CCGTTTTCTCATAGCGGTCATATTCTCCCAACCCCAACACCGATACATCCAAGCAGCTCCTTGTCTTTTGGGCATCCTCATCCAA GCTCAATGGTCACAGCAATGGGC SEQIDNo.29-GATA2(fromvector4) ATGGAAGTCGCCCCAGAACAACCTAGGTGGATGGCCCATCCTGCAGTACTCAACGCCCAACATCCTGATAGTCATCATCCCGG ATTGGCACATAATTATATGGAGCCGGCTCAACTCCTTCCCCCGGATGAAGTCGATGTTTTCTTTAACCATTTGGATAGTCAAGG AAATCCATATTACGCGAATCCTGCCCATGCCCGTGCCAGGGTGAGCTATTCCCCTGCCCATGCTAGACTCACTGGTGGTCAAAT GTGTAGGCCCCATCTTCTCCATTCCCCTGGACTGCCTTGGTTGGATGGCGGAAAGGCTGCTCTGTCCGCTGCCGCCGCACATCA TCATAATCCTTGGACAGTCAGTCCTTTTAGCAAAACACCACTCCATCCTTCTGCTGCCGGCGGACCCGGCGGTCCTCTGTCAGTT TATCCGGGCGCTGGTGGCGGCTCTGGTGGTGGATCAGGTTCTTCCGTCGCAAGCCTGACTCCCACTGCCGCGCATTCCGGTAG CCATCTCTTTGGTTTTCCCCCTACACCCCCAAAGGAAGTCTCCCCCGATCCCTCAACTACTGGCGCGGCTAGTCCTGCGTCCTCTT CTGCCGGCGGCAGCGCTGCTCGCGGTGAAGATAAAGATGGAGTGAAATATCAAGTTAGCCTCACCGAATCTATGAAAATGGA GAGCGGATCTCCTTTGCGTCCCGGGTTGGCCACCATGGGTACACAACCAGCCACCCATCATCCTATTCCTACTTATCCGAGCTA CGTACCTGCTGCCGCACATGATTATTCATCTGGGCTGTTTCATCCAGGCGGGTTTCTCGGTGGCCCCGCAAGCTCATTTACTCCC AAACAAAGGTCCAAAGCGCGGAGCTGCAGTGAGGGGAGAGAATGCGTGAATTGCGGCGCAACCGCTACGCCCTTGTGGAGA AGGGATGGAACGGGGCATTATCTCTGTAACGCATGCGGGTTGTATCATAAAATGAACGGCCAAAATCGCCCCTTGATAAAACC AAAGAGACGGTTGTCAGCTGCACGACGCGCTGGAACTTGCTGCGCCAACTGCCAAACCACCACAACAACATTGTGGCGGCGT AATGCAAATGGCGATCCCGTGTGTAATGCTTGCGGTCTGTATTATAAATTGCATAACGTGAATAGACCCCTCACTATGAAGAAA GAGGGCATACAAACCCGCAATCGCAAAATGTCAAATAAAAGCAAGAAGTCTAAGAAGGGCGCCGAATGTTTTGAAGAATTGT CTAAATGTATGCAAGAAAAGAGCAGCCCATTTTCCGCCGCCGCACTCGCAGGCCATATGGCCCCAGTAGGTCATCTGCCCCCTT TTAGTCATAGCGGGCATATTTTGCCTACGCCAACACCGATTCATCCTAGCAGCTCACTGTCTTTTGGGCATCCACATCCAAGTTC TATGGTCACGGCTATGGGTTGA SEQIDNo.30-GATA2(fromvector5) ATGGAAGTAGCCCCTGAACAACCCAGATGGATGGCTCATCCAGCAGTATTGAACGCACAACATCCAGATTCCCATCATCCAGG ATTGGCCCATAATTATATGGAGCCAGCCCAACTCTTGCCACCTGATGAAGTCGATGTTTTCTTTAACCATCTGGATAGTCAAGG TAATCCTTATTACGCTAATCCAGCACATGCACGCGCTCGGGTTTCATATTCCCCTGCCCATGCAAGGCTTACAGGCGGACAAAT GTGTCGTCCTCATCTGCTCCATTCCCCAGGCCTTCCATGGCTTGATGGCGGGAAGGCGGCGCTTTCAGCGGCGGCTGCACATC ATCATAATCCGTGGACTGTCTCTCCTTTTAGTAAAACTCCGCTTCATCCGAGCGCAGCAGGCGGACCTGGCGGACCCCTGTCAG TCTATCCTGGTGCCGGTGGCGGCTCCGGCGGTGGGTCCGGTTCCAGCGTTGCAAGCTTGACACCAACGGCGGCTCATTCAGGA TCACATTTGTTTGGTTTTCCCCCAACCCCGCCGAAAGAGGTCAGTCCCGATCCAAGTACAACCGGAGCAGCAAGTCCCGCAAGC TCATCTGCCGGCGGCTCCGCCGCTAGAGGCGAAGATAAAGATGGGGTAAAATATCAAGTCTCTCTTACCGAATCCATGAAAAT GGAGTCTGGATCTCCTCTCCGGCCCGGGCTCGCGACCATGGGGACACAACCCGCAACCCATCATCCAATTCCAACTTATCCAAG CTACGTTCCCGCTGCAGCACATGATTATTCATCTGGGCTGTTTCATCCGGGGGGATTTCTCGGTGGCCCAGCATCTTCTTTTACT CCCAAACAACGGTCTAAAGCAAGGTCTTGCAGTGAGGGTAGGGAATGCGTGAATTGCGGAGCTACTGCAACTCCCCTGTGGC GTCGCGATGGGACAGGTCATTATCTTTGTAACGCTTGCGGACTTTATCATAAAATGAACGGCCAAAATCGCCCGCTGATTAAAC CTAAACGCAGGTTGTCAGCGGCTCGCAGGGGGGGGACATGCTGCGCCAACTGCCAAACCACCACTACAACACTGTGGCGAAG AAATGCAAATGGCGATCCCGTGTGTAATGCTTGCGGGCTTTATTATAAACTCCATAACGTCAATCGGCCTCTTACAATGAAGAA AGAGGGAATTCAAACCAGGAATAGGAAAATGTCAAATAAAAGCAAGAAATCAAAGAAGGGCGCCGAATGTTTTGAAGAATT GTCTAAATGTATGCAAGAGAAATCTTCACCGTTTTCCGCCGCCGCGTTGGCCGGTCATATGGCTCCAGTCGGACATCTTCCGCC ATTTTCACATAGTGGGCATATTCTTCCAACACCCACACCTATTCATCCTTCATCTTCTCTGTCATTTGGACATCCTCATCCTAGCTC CATGGTTACTGCAATGGGC SEQIDNo.31-GATA2(fromvector6) ATGGAAGTTGCCCCGGAACAACCCCGTTGGATGGCCCATCCTGCAGTACTTAACGCCCAACATCCGGATTCCCATCATCCCGGA CTCGCTCATAATTATATGGAGCCGGCTCAACTCTTGCCACCCGATGAAGTCGATGTGTTCTTTAACCATCTGGATTCTCAAGGG AATCCATATTACGCAAATCCAGCACATGCCCGAGCCAGAGTTAGCTATTCACCTGCCCATGCAAGATTGACTGGTGGACAAAT GTGTCGGCCCCATCTGCTCCATTCACCAGGGCTCCCATGGCTTGATGGCGGTAAGGCTGCGCTGAGCGCTGCCGCCGCACATC ATCATAATCCATGGACAGTATCTCCCTTTTCTAAAACTCCCCTTCATCCTTCTGCAGCCGGTGGACCCGGCGGACCTTTGAGTGT TTATCCTGGCGCAGGCGGCGGTTCCGGCGGCGGGAGTGGAAGCAGTGTCGCGAGTCTGACGCCCACTGCTGCACATTCAGGA AGTCATCTGTTTGGGTTTCCCCCAACTCCACCCAAAGAGGTTTCCCCAGATCCAAGTACAACCGGCGCAGCCAGTCCCGCTTCC TCTAGCGCCGGCGGCTCAGCTGCTAGAGGGGAAGATAAAGATGGTGTTAAATATCAAGTTAGCCTTACTGAATCTATGAAAAT GGAGTCAGGGAGCCCGCTCAGACCCGGGCTGGCGACGATGGGTACACAACCGGCCACTCATCATCCTATTCCGACGTATCCG AGTTACGTTCCCGCCGCCGCTCATGATTATTCTTCCGGCCTGTTTCATCCAGGCGGTTTTCTTGGCGGCCCCGCGAGCTCATTTA CGCCCAAACAAAGGAGTAAAGCCAGATCTTGCTCTGAGGGGAGAGAATGCGTGAATTGCGGCGCGACGGCAACTCCCTTGTG GCGCCGCGATGGTACTGGGCATTATCTCTGTAACGCATGCGGATTGTATCATAAAATGAACGGTCAAAATAGGCCTCTGATAA AACCTAAACGGCGCCTTAGTGCGGCAAGGCGTGCAGGAACATGCTGCGCTAACTGCCAAACAACTACAACTACTTTGTGGCGG CGCAATGCGAATGGTGATCCCGTGTGTAATGCTTGCGGATTGTATTATAAACTCCATAACGTGAATCGTCCTCTCACTATGAAG AAGGAAGGAATTCAAACGCGCAATAGGAAAATGTCTAATAAAAGCAAGAAGTCCAAGAAGGGCGCTGAATGTTTTGAAGAAC TCAGCAAATGTATGCAAGAGAAATCCAGTCCATTTTCAGCCGCCGCACTTGCAGGTCATATGGCTCCCGTCGGGCATTTGCCAC CGTTTTCCCATAGCGGTCATATTCTCCCAACCCCTACTCCAATACATCCTTCTAGCTCTCTGAGTTTTGGGCATCCTCATCCCAGT TCCATGGTCACAGCGATGGGTTGA SEQIDNo.32-GFI1B(fromvector1) ATGCCGAGGAGCTTTCTCGTTAAATCCAAGAAAGCGCATACATATCATCAACCTAGGGTCCAAGAGGACGAGCCACTGTGGCC ACCCGCTCTCACACCAGTTCCTCGGGATCAAGCACCTTCTAATTCACCCGTGTTGAGTACCTTGTTTCCGAATCAATGTCTCGAT TGGACTAATCTGAAGCGGGAACCAGAATTGGAACAAGATCAAAATCTGGCACGCATGGCTCCCGCTCCTGAAGGTCCAATCGT TCTCAGTCGGCCGCAAGACGGCGATTCCCCGCTTTCTGATAGCCCACCGTTTTATAAACCATCTTTTAGCTGGGATACGCTCGCT ACGACATACGGTCATTCCTATAGACAAGCTCCGTCAACTATGCAAAGCGCTTTTCTCGAACATAGCGTTTCACTTTATGGATCAC CCCTCGTCCCTTCCACCGAACCTGCTCTGGACTTTTCCCTGAGATATTCTCCCGGGATGGACGCCTATCATTGCGTTAAATGTAA TAAAGTGTTTTCAACACCGCATGGTCTTGAGGTCCACGTACGCCGATCACACAGCGGCACTCGCCCGTTTGCATGCGATATTTG TGGAAAGACTTTTGGACATGCCGTCTCTCTCGAACAACATACACATGTGCATTCACAAGAACGTTCCTTTGAATGTCGAATGTG TGGGAAAGCGTTTAAAAGGTCAAGTACCCTCAGCACGCATCTTCTTATTCATTCTGATACCCGCCCTTATCCATGTCAATTTTGT GGGAAACGCTTTCATCAGAAAAGTGATATGAAGAAACATACGTATATTCATACCGGGGAAAAGCCACATAAATGTCAAGTATG TGGCAAAGCATTTTCCCAAAGTTCTAATTTGATAACGCATAGTCGAAAACATACTGGGTTTAAACCATTTTCCTGCGAACTCTGT ACTAAGGGATTTCAAAGGAAAGTAGATCTTAGAAGGCATAGGGAATCCCAACATAACCTGAAA SEQIDNo.33-GFI1B(fromvector2) ATGCCCCGGAGTTTTCTTGTTAAATCCAAGAAAGCCCATACATATCATCAACCTCGCGTCCAAGAGGACGAGCCACTGTGGCCC CCAGCTCTGACGCCTGTACCTCGGGATCAAGCACCGTCTAATTCTCCCGTGCTGTCAACCCTGTTTCCTAATCAATGTCTTGATT GGACTAATCTTAAGCGCGAACCAGAACTCGAACAAGATCAAAATCTGGCACGGATGGCTCCTGCCCCCGAAGGACCAATCGTA CTCTCTCGGCCTCAAGACGGCGATAGTCCCTTGTCAGATTCACCCCCATTTTATAAACCATCCTTTAGTTGGGATACACTCGCTA CTACATACGGTCATTCATATAGACAAGCTCCATCTACAATGCAATCCGCGTTTCTCGAACATAGCGTGAGTCTTTATGGTAGCCC ACTGGTTCCAAGTACCGAACCGGCACTGGATTTCTCACTTCGTTATAGCCCTGGGATGGACGCTTATCATTGCGTCAAATGTAA TAAAGTGTTTAGTACGCCCCATGGACTGGAAGTCCACGTAAGGCGGAGTCACTCCGGCACTAGACCTTTTGCATGCGATATAT GTGGGAAGACTTTTGGTCATGCCGTTTCCCTTGAACAACATACTCATGTGCATTCTCAAGAAAGATCCTTTGAATGTCGGATGT GTGGAAAAGCATTTAAAAGGTCATCAACTCTCAGCACTCATTTGCTGATTCATTCTGATACCCGCCCATATCCTTGTCAATTTTG TGGTAAAAGGTTTCATCAGAAAAGCGATATGAAGAAACATACCTACATTCATACTGGAGAGAAGCCCCATAAATGTCAAGTTT GTGGTAAGGCATTTTCACAATCTTCTAACCTGATAACACATTCCCGGAAACATACTGGATTTAAACCATTTTCTTGCGAACTCTG TACAAAGGGTTTTCAAAGAAAAGTAGATCTCCGTAGGCATCGTGAATCACAACATAACCTGAAATAA SEQIDNo.34-GFI1B(fromvector3) ATGCCCAGAAGCTTTCTCGTCAAATCAAAGAAAGCCCATACATATCATCAACCTCGGGTTCAAGAGGACGAGCCTTTGTGGCC ACCAGCTCTCACACCAGTCCCTCGGGATCAAGCCCCTTCAAATAGTCCAGTACTCTCTACACTCTTTCCTAATCAATGTTTGGATT GGACAAATCTGAAGCGGGAACCAGAACTTGAACAAGATCAAAATCTGGCACGGATGGCACCTGCGCCTGAAGGACCAATCGT CTTGTCTAGGCCTCAAGACGGCGATAGCCCGCTCAGCGATTCCCCACCGTTTTATAAACCCAGTTTTAGCTGGGATACACTGGC TACGACATACGGACATTCATATAGGCAAGCTCCTAGTACTATGCAATCCGCATTTCTCGAACATAGCGTGTCTTTGTATGGGAG CCCGCTCGTACCTTCTACCGAACCTGCGCTGGATTTTAGTCTGCGTTATAGCCCTGGGATGGACGCCTATCATTGCGTCAAATG TAATAAAGTCTTTAGCACTCCCCATGGCCTGGAAGTCCACGTCCGGCGAAGTCACTCTGGTACTAGACCATTTGCTTGCGATAT TTGTGGAAAGACTTTTGGACATGCCGTCAGTCTTGAACAACATACACATGTGCATTCTCAAGAACGGTCCTTTGAATGTCGGAT GTGTGGGAAAGCTTTTAAAAGAAGCTCTACTCTCTCAACGCATCTCTTGATTCATAGCGATACACGTCCTTATCCATGTCAATTT TGTGGAAAACGCTTCCATCAAAAGTCAGATATGAAGAAACATACTTATATTCATACTGGCGAGAAACCACACAAATGTCAAGT TTGCGGCAAAGCATTTTCCCAATCCTCAAATCTGATTACTCATTCCAGAAAACATACTGGGTTTAAACCATTTTCCTGCGAACTT TGTACGAAGGGTTTTCAAAGGAAAGTTGATTTGCGACGCCATAGAGAATCCCAACATAACCTGAAA SEQIDNo.35-GFI1B(fromvector4) ATGCCGAGATCATTTCTCGTCAAAAGTAAGAAGGCGCATACTTATCATCAACCTCGCGTTCAAGAGGACGAGCCCTTGTGGCC CCCAGCGTTGACACCTGTTCCTCGCGATCAAGCACCCTCTAATAGTCCCGTGCTCTCAACCCTGTTTCCTAATCAATGTTTGGAT TGGACAAATCTGAAGCGTGAACCTGAATTGGAACAAGATCAAAATCTTGCACGCATGGCGCCAGCGCCTGAAGGTCCAATCGT CCTCAGTAGACCACAAGACGGAGATAGCCCGTTGAGCGATTCTCCACCCTTTTATAAACCATCCTTTAGTTGGGATACACTGGC AACGACATACGGACATAGTTATAGGCAAGCTCCATCTACTATGCAATCTGCGTTTCTGGAACATAGCGTTTCTCTTTATGGGTCT CCGCTGGTTCCATCAACAGAACCTGCGCTGGATTTTAGCCTGAGATATAGTCCTGGGATGGACGCATATCATTGCGTAAAATGT AATAAAGTGTTTAGCACACCACATGGCCTGGAAGTCCACGTTCGGCGGAGCCACAGCGGCACAAGGCCATTTGCATGCGATAT TTGTGGGAAGACGTTTGGACATGCCGTTTCCCTCGAACAACATACACATGTTCATAGCCAAGAAAGATCATTTGAATGTAGAAT GTGTGGGAAAGCATTTAAACGGTCTAGCACACTCTCTACGCATCTCCTGATTCATAGCGATACTCGCCCATATCCTTGTCAATTT TGCGGGAAAAGATTTCATCAAAAGTCAGATATGAAGAAGCATACGTATATTCATACCGGGGAGAAACCACATAAATGTCAAGT CTGTGGCAAAGCCTTTTCCCAGTCATCTAATTTGATAACACATAGTAGGAAACATACCGGTTTTAAACCGTTTTCTTGCGAACTC TGTACAAAGGGTTTTCAAAGAAAAGTTGATCTCCGTAGACATAGGGAATCCCAACATAACCTGAAA SEQIDNo.36-GFI1B(fromvector5) ATGCCCCGAAGTTTTCTCGTTAAATCAAAGAAAGCACATACTTATCATCAACCTCGCGTCCAAGAGGACGAGCCACTTTGGCCA CCCGCTCTGACACCTGTCCCGAGGGATCAAGCGCCGTCCAATTCACCCGTGTTGTCTACCCTCTTTCCCAATCAATGTTTGGATT GGACAAATTTGAAGAGGGAACCAGAACTTGAACAAGATCAAAATCTTGCGCGGATGGCGCCTGCCCCGGAAGGGCCAATCGT CCTCAGCCGGCCGCAAGACGGCGATTCCCCTCTTAGCGATAGCCCACCATTTTATAAACCCAGTTTTAGCTGGGATACTCTGGC TACTACTTACGGACATTCATATAGACAAGCGCCTTCAACGATGCAAAGCGCATTTCTTGAACATAGTGTGTCCCTTTATGGTTCC CCACTCGTTCCTTCCACAGAACCAGCTCTGGATTTCTCACTTCGATATTCTCCCGGGATGGACGCTTATCATTGCGTAAAATGTA ATAAAGTGTTTTCTACACCGCATGGTCTGGAAGTCCACGTACGCCGTAGTCACTCCGGCACAAGGCCTTTTGCGTGCGATATTT GTGGGAAGACGTTTGGTCATGCCGTATCACTCGAACAACATACACATGTGCATTCTCAAGAACGGAGTTTTGAATGTAGAATG TGTGGTAAAGCTTTTAAAAGGTCATCAACTTTGAGTACTCATCTCTTGATACACAGCGATACAAGGCCGTATCCATGTCAATTTT GTGGAAAACGGTTTCATCAAAAGTCAGATATGAAGAAACATACATATATTCATACCGGGGAAAAGCCCCATAAATGTCAAGTC TGTGGTAAAGCGTTTTCTCAATCTAGTAATCTGATTACACATTCTCGTAAACATACTGGGTTTAAACCTTTCTCTTGCGAACTTTG TACAAAGGGATTTCAACGGAAAGTCGATCTTCGTAGACATAGAGAATCCCAACATAACCTTAAATAA SEQIDNo.37-GFI1B(fromvector6) ATGCCCCGTTCTTTCTTGGTAAAATCCAAGAAGGCGCATACATATCATCAACCACGGGTTCAAGAGGACGAGCCACTGTGGCC GCCAGCTCTGACTCCCGTCCCTCGGGATCAAGCCCCCTCTAATTCTCCCGTGCTGTCAACATTGTTTCCTAATCAATGTTTGGATT GGACTAATCTGAAGCGCGAACCAGAATTGGAACAAGATCAAAATCTCGCTCGGATGGCTCCTGCTCCGGAAGGTCCTATCGTT CTTTCAAGACCACAAGACGGCGATTCACCCCTCTCAGATTCTCCCCCTTTCTATAAACCCAGCTTTAGTTGGGATACTCTGGCAA CCACATACGGGCATTCTTATCGCCAAGCGCCAAGCACAATGCAAAGTGCATTTCTCGAACATTCAGTATCTCTTTATGGATCTCC CCTGGTCCCTTCTACCGAACCAGCGCTTGACTTTTCCTTGAGGTATAGTCCCGGGATGGACGCATATCATTGCGTAAAATGTAA TAAAGTTTTCAGCACGCCCCATGGATTGGAAGTCCACGTCAGGCGATCTCACTCTGGCACAAGACCTTTTGCATGCGATATTTG TGGTAAGACGTTTGGACATGCCGTTTCACTCGAACAACATACACATGTTCATAGCCAAGAACGTTCATTTGAATGTAGAATGTG TGGAAAAGCATTTAAAAGGAGCTCTACCCTTTCTACACATTTGCTGATTCATAGCGATACCCGACCTTATCCGTGTCAATTTTGT GGAAAACGATTTCATCAGAAATCAGATATGAAGAAGCATACATATATACATACCGGGGAGAAACCCCATAAATGTCAAGTCTG TGGCAAAGCATTTTCTCAATCAAGCAATCTGATTACTCATTCCAGAAAACATACTGGATTTAAACCCTTTTCATGCGAACTTTGT ACTAAGGGATTTCAACGGAAAGTTGATTTGAGGAGACATCGAGAAAGTCAACATAACCTGAAA SEQIDNo.38-FOS(fromvector1) ATGATGTTTTCCGGGTTTAATGCCGATTATGAAGCATCCAGTTCTAGGTGTAGTTCTGCAAGTCCCGCGGGCGACTCACTGTCA TATTATCATAGCCCGGCTGATAGCTTTTCTTCTATGGGGTCACCCGTGAATGCCCAAGATTTCTGTACTGATTTGGCAGTGAGCT CAGCTAATTTTATCCCTACTGTGACCGCTATAAGCACTTCTCCTGATCTCCAATGGCTCGTCCAACCAGCACTGGTTAGTTCAGT CGCTCCCAGTCAAACACGGGCACCCCATCCGTTTGGGGTTCCAGCACCTTCAGCAGGCGCCTATAGCCGGGCCGGAGTCGTAA AGACAATGACTGGTGGGAGAGCCCAATCAATCGGAAGAAGAGGAAAAGTCGAGCAACTTAGCCCTGAGGAAGAGGAAAAG AGACGCATTAGGCGCGAGCGGAACAAAATGGCCGCCGCTAAGTGTCGAAATAGGCGTCGTGAACTCACAGACACCCTGCAGG CCGAAACCGATCAGCTTGAGGACGAGAAAAGTGCACTGCAAACTGAAATCGCTAATCTTCTCAAAGAGAAAGAGAAGCTGGA ATTTATTCTCGCTGCACATCGTCCAGCATGTAAAATTCCCGACGATCTCGGATTTCCGGAAGAAATGAGCGTAGCCAGTCTCGA CCTTACCGGTGGACTCCCTGAAGTCGCGACACCTGAATCCGAAGAAGCGTTTACATTGCCCTTGCTGAACGATCCGGAACCAA AACCAAGCGTCGAGCCCGTGAAAAGTATATCATCTATGGAACTTAAAACTGAACCTTTCGACGATTTTCTCTTTCCTGCTTCCAG CCGCCCATCAGGGTCAGAAACCGCTAGATCTGTCCCCGATATGGATCTGAGCGGAAGCTTTTACGCTGCCGATTGGGAACCAC TCCATTCAGGTAGTCTTGGCATGGGCCCTATGGCGACCGAACTTGAACCTCTTTGTACACCCGTTGTAACTTGCACCCCATCCTG TACGGCCTATACCTCAAGTTTTGTATTTACATATCCTGAAGCCGATTCTTTTCCATCCTGCGCCGCCGCGCATCGAAAAGGGTCT TCATCTAACGAACCATCTTCCGATAGTTTGAGTAGTCCAACCCTTCTTGCTCTCTAA SEQIDNo.39-FOS(fromvector2) ATGATGTTTTCAGGGTTTAATGCCGATTATGAAGCCAGTTCTTCAAGATGTTCCTCAGCTTCCCCCGCAGGCGACTCCTTGTCCT ATTATCATTCTCCAGCTGATAGCTTTAGTTCCATGGGGTCCCCCGTTAATGCCCAAGACTTTTGTACTGATCTCGCGGTTAGCAG CGCAAATTTTATACCGACTGTGACAGCAATATCAACATCTCCAGATCTTCAATGGCTCGTTCAACCTGCACTGGTGAGCTCTGTC GCACCTTCACAAACGCGGGCTCCACATCCATTTGGCGTTCCTGCACCAAGTGCAGGTGCCTATAGCCGCGCAGGGGTGGTTAA AACAATGACTGGTGGAAGAGCCCAATCCATCGGGCGCCGGGGAAAAGTAGAGCAACTGTCCCCCGAGGAAGAGGAAAAGCG TCGTATTAGGCGCGAGCGGAACAAAATGGCGGCTGCAAAGTGTAGAAATAGGCGCCGCGAATTGACAGACACCCTGCAGGC AGAAACCGATCAGCTCGAGGACGAAAAGTCCGCCCTTCAAACTGAAATCGCAAATTTGCTTAAAGAGAAAGAGAAGTTGGAA TTTATACTCGCTGCCCATCGGCCAGCATGTAAAATACCCGACGATTTGGGTTTTCCCGAGGAAATGTCAGTAGCCTCTCTCGAC CTTACGGGCGGACTTCCCGAAGTGGCGACTCCTGAAAGTGAAGAAGCATTTACACTTCCCCTGCTGAACGATCCAGAACCTAA ACCTTCCGTCGAGCCCGTAAAATCAATTTCTTCCATGGAATTGAAAACAGAACCTTTCGACGATTTTCTCTTTCCTGCCAGTTCA CGCCCATCCGGGAGTGAAACCGCTCGAAGCGTTCCGGATATGGATCTTAGCGGCAGCTTTTACGCTGCTGATTGGGAACCGCT TCATAGCGGGTCATTGGGTATGGGACCAATGGCTACCGAACTTGAACCATTGTGTACCCCAGTTGTGACATGCACCCCTTCTTG TACCGCGTATACTTCAAGCTTTGTATTTACATATCCTGAAGCCGATTCATTTCCAAGTTGCGCCGCCGCTCATAGGAAAGGGTCT AGTAGTAACGAACCAAGTTCAGATTCACTGTCCAGCCCTACATTGTTGGCTCTC SEQIDNo.40-FOS(fromvector3) ATGATGTTTTCAGGGTTTAATGCCGATTATGAAGCCAGTTCATCTCGATGTTCATCAGCCAGCCCTGCTGGCGACTCACTGAGC TATTATCATTCTCCAGCTGATTCATTTTCTTCTATGGGGAGCCCAGTAAATGCACAAGACTTTTGTACCGATCTCGCAGTTTCAA GCGCGAATTTTATCCCAACCGTGACCGCTATTAGCACTTCTCCAGATCTCCAATGGCTTGTCCAACCGGCTCTGGTGAGTAGCG TCGCTCCGAGCCAAACGAGGGCACCCCATCCGTTTGGTGTACCAGCACCAAGCGCAGGAGCATATTCTCGCGCGGGTGTAGTC AAAACAATGACTGGCGGGCGCGCCCAAAGTATCGGTCGCAGAGGTAAAGTAGAGCAACTGAGCCCCGAGGAAGAGGAAAA GCGACGGATTAGACGTGAGCGGAACAAAATGGCCGCCGCTAAGTGTCGGAATAGACGACGAGAACTTACAGACACTCTGCA GGCCGAAACCGATCAGTTGGAAGACGAAAAGTCCGCACTCCAAACAGAAATCGCGAATCTTTTGAAAGAGAAAGAGAAGCTC GAATTTATTCTTGCCGCACATCGCCCCGCGTGTAAAATACCCGACGATCTTGGATTTCCTGAGGAAATGTCCGTTGCAAGCCTG GACCTCACCGGCGGACTTCCGGAAGTCGCAACACCCGAAAGTGAAGAAGCTTTTACTCTTCCCCTGCTGAACGATCCCGAACCT AAACCTTCTGTTGAGCCCGTTAAATCAATAAGTAGTATGGAACTCAAAACTGAACCATTCGACGATTTTCTGTTTCCCGCTTCCA GTAGACCAAGCGGGAGCGAAACTGCACGATCTGTCCCGGATATGGATCTGTCAGGCTCATTTTACGCGGCCGATTGGGAACC ACTCCATTCCGGATCTCTCGGCATGGGACCAATGGCTACCGAACTTGAACCACTTTGTACCCCCGTCGTAACGTGCACACCATC CTGTACCGCGTATACTAGCTCTTTTGTATTTACTTATCCGGAAGCGGATTCATTTCCAAGTTGCGCCGCCGCTCATAGAAAAGG GTCTTCATCTAACGAACCGTCTTCCGATTCCCTGAGTAGTCCTACCCTTTTGGCATTGTAA SEQIDNo.41-FOS(fromvector4) ATGATGTTTAGCGGATTTAATGCCGATTATGAAGCAAGCTCAAGCAGGTGTTCCTCAGCTTCTCCCGCTGGAGACTCTCTGTCA TATTATCATAGCCCAGCCGATAGCTTTTCTTCCATGGGTTCCCCAGTTAATGCTCAAGATTTCTGTACCGATCTCGCGGTGAGTA GCGCAAATTTTATACCAACCGTGACCGCTATTTCTACATCTCCCGATCTTCAATGGTTGGTCCAACCTGCTCTGGTGAGTTCTGT CGCACCCTCTCAAACTCGGGCACCGCATCCCTTTGGCGTACCAGCACCAAGCGCCGGAGCCTATAGCCGGGCAGGGGTGGTC AAAACTATGACCGGTGGGCGTGCCCAATCCATAGGACGCCGCGGGAAAGTCGAGCAATTGAGCCCGGAAGAAGAGGAAAAG CGGCGCATTCGCCGGGAGCGAAACAAAATGGCCGCCGCTAAGTGTCGTAATAGACGCCGCGAACTCACCGACACGTTGCAGG CTGAAACCGATCAGCTCGAGGACGAGAAAAGTGCGCTCCAAACGGAAATCGCTAATCTTCTCAAAGAAAAGGAGAAGCTTGA ATTTATTTTGGCCGCCCATCGCCCCGCTTGTAAAATACCGGACGATCTTGGGTTTCCCGAGGAAATGAGTGTCGCCTCTCTGGA CCTCACCGGCGGATTGCCTGAAGTGGCTACACCAGAATCCGAAGAAGCGTTTACGCTCCCCCTGCTGAACGATCCCGAACCAA AACCATCCGTTGAGCCAGTGAAATCAATATCATCCATGGAACTTAAAACAGAACCTTTCGACGATTTTCTGTTTCCTGCCAGCTC ACGCCCGAGCGGTTCAGAAACCGCGAGGTCTGTACCCGATATGGATCTGTCAGGTTCATTTTACGCTGCCGATTGGGAACCCT TGCATAGCGGTTCTTTGGGCATGGGACCTATGGCTACCGAACTCGAACCTCTCTGTACACCTGTCGTGACATGCACACCTTCTT GTACCGCCTATACCTCAAGTTTTGTGTTTACTTATCCAGAAGCCGATAGCTTTCCTAGTTGCGCTGCCGCACATCGTAAAGGAA GTTCCTCAAACGAACCGAGTTCCGATTCTCTTAGTAGCCCAACCCTTTTGGCACTT SEQIDNo.42-FOS(fromvector5) ATGATGTTTTCAGGATTTAATGCTGATTATGAAGCCAGCTCTAGTAGGTGTTCCTCTGCAAGCCCAGCTGGTGACTCCCTGTCA TATTATCATAGTCCTGCTGATAGCTTTAGTTCTATGGGATCTCCAGTGAATGCCCAAGACTTTTGTACAGATCTCGCAGTAAGCA GCGCAAATTTTATCCCGACTGTTACCGCTATTTCCACTTCACCCGATCTCCAATGGCTTGTCCAACCAGCGCTGGTGAGTAGTGT TGCTCCGAGCCAAACACGGGCTCCCCATCCCTTTGGGGTGCCTGCTCCGAGCGCAGGCGCATATAGCCGTGCCGGAGTGGTG AAAACAATGACCGGCGGACGGGCACAATCTATCGGGCGTAGAGGTAAAGTCGAGCAACTGAGTCCTGAGGAAGAGGAAAAG AGACGGATTAGGCGGGAGCGCAACAAAATGGCAGCCGCAAAGTGTCGAAATAGAAGACGCGAACTCACGGACACCCTGCAG GCAGAAACTGATCAGCTTGAGGACGAAAAGAGTGCCCTGCAAACTGAAATCGCAAATCTTCTCAAAGAAAAGGAGAAGCTGG AATTTATTCTCGCCGCACATAGGCCCGCTTGTAAAATTCCCGACGATCTCGGATTTCCTGAGGAAATGAGCGTTGCCTCACTGG ACCTTACAGGCGGGTTGCCCGAAGTGGCTACTCCCGAATCAGAAGAAGCATTTACTCTTCCCCTGCTGAACGATCCCGAACCAA AACCATCCGTTGAGCCGGTGAAATCTATTAGTTCAATGGAATTGAAAACTGAACCTTTCGACGATTTTCTCTTTCCTGCCTCTAG CCGACCATCAGGGTCCGAAACGGCTCGTAGTGTACCTGATATGGATCTGAGCGGTAGCTTTTACGCCGCCGATTGGGAACCTC TCCATTCCGGTTCATTGGGCATGGGACCGATGGCTACTGAATTGGAACCGCTCTGTACCCCAGTAGTGACATGCACACCTTCAT GTACAGCATATACATCAAGCTTTGTGTTTACTTATCCGGAAGCCGATTCTTTTCCTTCTTGCGCTGCCGCTCATAGGAAAGGCTC CTCTTCTAACGAACCAAGTAGTGATTCACTGTCATCCCCTACACTTTTGGCTCTT SEQIDNo.43-FOS(fromvector6) ATGATGTTTAGCGGATTTAATGCCGATTATGAAGCAAGCTCATCTCGATGTTCATCTGCAAGCCCAGCTGGTGACTCACTGAGC TATTATCATAGCCCGGCTGATTCATTTTCATCTATGGGTTCCCCCGTTAATGCCCAAGACTTTTGTACCGATCTCGCAGTGAGCA GCGCAAATTTTATCCCTACCGTGACCGCTATATCAACTAGCCCCGATTTGCAATGGCTTGTCCAACCAGCGTTGGTGTCAAGCG TTGCACCCAGCCAAACTCGCGCTCCCCATCCCTTTGGCGTGCCAGCTCCGAGCGCAGGCGCCTATTCACGGGCAGGGGTAGTC AAAACAATGACCGGCGGACGCGCTCAATCCATCGGAAGAAGAGGGAAAGTCGAGCAACTCTCCCCCGAGGAAGAGGAAAAG CGACGCATTAGAAGAGAGCGGAACAAAATGGCCGCCGCTAAGTGTCGGAATAGACGCCGCGAACTCACCGACACTCTGCAGG CCGAAACCGATCAGCTGGAAGACGAAAAGAGTGCCCTTCAAACTGAAATCGCAAATCTCTTGAAAGAAAAGGAGAAGCTGGA ATTTATTCTTGCTGCACATCGTCCAGCATGTAAAATTCCGGACGATTTGGGGTTTCCCGAGGAAATGTCCGTTGCCTCTCTCGAC TTGACCGGTGGGTTGCCTGAAGTAGCTACACCCGAAAGTGAAGAAGCGTTTACTCTTCCATTGCTTAACGATCCAGAACCAAA ACCAAGCGTTGAGCCCGTAAAATCTATTTCTTCAATGGAACTCAAAACTGAACCATTCGACGATTTTCTCTTTCCTGCTTCTAGT AGACCATCTGGCTCCGAAACCGCACGATCTGTACCTGATATGGATCTGTCCGGAAGCTTTTACGCCGCCGATTGGGAACCACTC CATTCCGGTTCACTCGGAATGGGACCTATGGCTACGGAATTGGAACCTCTTTGTACCCCAGTTGTAACTTGCACCCCATCATGT ACCGCCTATACCTCTAGCTTTGTATTTACGTATCCTGAAGCCGATAGCTTTCCATCTTGCGCCGCCGCGCATAGGAAAGGATCTT CAAGTAACGAACCCAGTTCCGATAGTTTGAGTTCTCCGACACTTCTCGCTCTT SEQIDNo.44-GaGiFo ATGGAAGTCGCTCCTGAACAACCACGGTGGATGGCTCATCCTGCAGTTCTTAACGCTCAACATCCAGATAGCCATCATCCTGGG CTCGCTCATAATTATATGGAGCCTGCCCAACTCCTTCCCCCAGATGAAGTAGATGTATTCTTTAACCATCTTGATAGCCAAGGAA ATCCTTATTACGCAAATCCTGCCCATGCCAGAGCCAGAGTAAGCTATTCACCAGCCCATGCAAGGCTTACTGGTGGACAAATGT GTCGGCCCCATCTGCTGCATTCCCCCGGCCTGCCGTGGTTGGATGGCGGAAAGGCGGCTCTGAGTGCGGCGGCTGCACATCAT CATAATCCTTGGACAGTCTCACCTTTCTCTAAAACTCCCCTTCATCCTAGTGCAGCCGGTGGTCCAGGTGGTCCGCTGTCCGTTT ATCCCGGCGCCGGCGGCGGAAGTGGCGGCGGAAGTGGCAGTAGCGTAGCTTCATTGACACCCACAGCTGCTCATTCCGGAAG TCATCTCTTTGGGTTTCCCCCTACCCCGCCGAAAGAGGTTTCCCCAGATCCGTCAACTACCGGTGCCGCTTCCCCTGCTAGTTCC AGTGCCGGCGGAAGCGCTGCAAGGGGCGAAGATAAAGATGGAGTGAAATATCAAGTCTCCTTGACAGAATCCATGAAAATG GAGTCCGGTTCTCCACTCAGGCCTGGACTCGCCACAATGGGTACTCAACCCGCCACCCATCATCCAATACCGACTTATCCTTCAT ACGTACCAGCCGCCGCTCATGATTATTCATCAGGTTTGTTTCATCCAGGTGGATTTCTTGGCGGGCCTGCTAGTTCTTTTACACC AAAACAAAGGTCCAAAGCCAGGTCTTGCAGTGAGGGGCGCGAATGCGTAAATTGCGGCGCTACCGCAACACCACTGTGGCGT CGTGATGGAACAGGACATTATCTTTGTAACGCATGCGGGCTGTATCATAAAATGAACGGACAAAATCGGCCCCTGATTAAACC TAAACGTCGCTTGTCTGCTGCAAGGGGGCTGGGACGTGCTGCGCCAACTGCCAAACAACCACAACAACACTGTGGCGTAGG AATGCTAATGGCGATCCCGTATGTAATGCATGCGGTCTGTATTATAAACTTCATAACGTCAATCGGCCCCTTACTATGAAGAAA GAGGGCATACAAACCCGAAATCGCAAAATGTCAAATAAATCTAAGAAATCCAAGAAGGGAGCCGAATGTTTTGAAGAACTCA GCAAATGTATGCAAGAAAAGTCCAGCCCGTTTTCCGCCGCCGCTTTGGCCGGCCATATGGCCCCCGTCGGACATCTGCCACCG TTTTCCCATAGCGGTCATATTCTTCCTACACCCACCCCAATTCATCCGTCTAGCTCCCTGTCTTTTGGGCATCCTCATCCTAGCTCA ATGGTCACAGCTATGGGTGGCAGCGGCGCCACAAACTTCTCTCTGCTAAAGCAAGCAGGTGATGTTGAAGAAAACCCCGGGC CTATGCCGAGGAGCTTTCTCGTTAAATCCAAGAAAGCGCATACATATCATCAACCTAGGGTCCAAGAGGACGAGCCACTGTGG CCACCCGCTCTCACACCAGTTCCTCGGGATCAAGCACCTTCTAATTCACCCGTGTTGAGTACCTTGTTTCCGAATCAATGTCTCG ATTGGACTAATCTGAAGCGGGAACCAGAATTGGAACAAGATCAAAATCTGGCACGCATGGCTCCCGCTCCTGAAGGTCCAATC GTTCTCAGTCGGCCGCAAGACGGCGATTCCCCGCTTTCTGATAGCCCACCGTTTTATAAACCATCTTTTAGCTGGGATACGCTC GCTACGACATACGGTCATTCCTATAGACAAGCTCCGTCAACTATGCAAAGCGCTTTTCTCGAACATAGCGTTTCACTTTATGGAT CACCCCTCGTCCCTTCCACCGAACCTGCTCTGGACTTTTCCCTGAGATATTCTCCCGGGATGGACGCCTATCATTGCGTTAAATG TAATAAAGTGTTTTCAACACCGCATGGTCTTGAGGTCCACGTACGCCGATCACACAGCGGCACTCGCCCGTTTGCATGCGATAT TTGTGGAAAGACTTTTGGACATGCCGTCTCTCTCGAACAACATACACATGTGCATTCACAAGAACGTTCCTTTGAATGTCGAAT GTGTGGGAAAGCGTTTAAAAGGTCAAGTACCCTCAGCACGCATCTTCTTATTCATTCTGATACCCGCCCTTATCCATGTCAATTT TGTGGGAAACGCTTTCATCAGAAAAGTGATATGAAGAAACATACGTATATTCATACCGGGGAAAAGCCACATAAATGTCAAGT ATGTGGCAAAGCATTTTCCCAAAGTTCTAATTTGATAACGCATAGTCGAAAACATACTGGGTTTAAACCATTTTCCTGCGAACTC TGTACTAAGGGATTTCAAAGGAAAGTAGATCTTAGAAGGCATAGGGAATCCCAACATAACCTGAAAGGCTCCGGCGAGGGCA GGGGAAGTCTTCTAACATGCGGGGACGTGGAGGAAAATCCCGGCCCAATGATGTTTTCCGGGTTTAATGCCGATTATGAAGC ATCCAGTTCTAGGTGTAGTTCTGCAAGTCCCGCGGGCGACTCACTGTCATATTATCATAGCCCGGCTGATAGCTTTTCTTCTATG GGGTCACCCGTGAATGCCCAAGATTTCTGTACTGATTTGGCAGTGAGCTCAGCTAATTTTATCCCTACTGTGACCGCTATAAGC ACTTCTCCTGATCTCCAATGGCTCGTCCAACCAGCACTGGTTAGTTCAGTCGCTCCCAGTCAAACACGGGCACCCCATCCGTTTG GGGTTCCAGCACCTTCAGCAGGCGCCTATAGCCGGGCCGGAGTCGTAAAGACAATGACTGGTGGGAGAGCCCAATCAATCGG AAGAAGAGGAAAAGTCGAGCAACTTAGCCCTGAGGAAGAGGAAAAGAGACGCATTAGGCGCGAGCGGAACAAAATGGCCG CCGCTAAGTGTCGAAATAGGCGTCGTGAACTCACAGACACCCTGCAGGCCGAAACCGATCAGCTTGAGGACGAGAAAAGTGC ACTGCAAACTGAAATCGCTAATCTTCTCAAAGAGAAAGAGAAGCTGGAATTTATTCTCGCTGCACATCGTCCAGCATGTAAAAT TCCCGACGATCTCGGATTTCCGGAAGAAATGAGCGTAGCCAGTCTCGACCTTACCGGTGGACTCCCTGAAGTCGCGACACCTG AATCCGAAGAAGCGTTTACATTGCCCTTGCTGAACGATCCGGAACCAAAACCAAGCGTCGAGCCCGTGAAAAGTATATCATCT ATGGAACTTAAAACTGAACCTTTCGACGATTTTCTCTTTCCTGCTTCCAGCCGCCCATCAGGGTCAGAAACCGCTAGATCTGTCC CCGATATGGATCTGAGCGGAAGCTTTTACGCTGCCGATTGGGAACCACTCCATTCAGGTAGTCTTGGCATGGGCCCTATGGCG ACCGAACTTGAACCTCTTTGTACACCCGTTGTAACTTGCACCCCATCCTGTACGGCCTATACCTCAAGTTTTGTATTTACATATCC TGAAGCCGATTCTTTTCCATCCTGCGCCGCCGCGCATCGAAAAGGGTCTTCATCTAACGAACCATCTTCCGATAGTTTGAGTAG TCCAACCCTTCTTGCTCTCTAA SEQIDNo.45-GaFoGi ATGGAAGTCGCCCCGGAACAACCACGATGGATGGCACATCCTGCAGTTCTCAACGCACAACATCCTGATAGTCATCATCCAGG GTTGGCTCATAATTATATGGAGCCTGCCCAACTCCTTCCCCCTGATGAAGTTGATGTGTTCTTTAACCATCTGGATTCTCAAGGA AATCCGTATTACGCTAATCCAGCCCATGCACGCGCACGTGTTTCATATAGTCCTGCCCATGCGAGGCTTACAGGCGGGCAAAT GTGTCGTCCCCATCTCCTGCATTCTCCCGGCCTGCCGTGGCTTGATGGTGGAAAGGCTGCGCTGAGCGCTGCCGCCGCTCATCA TCATAATCCATGGACTGTCAGTCCGTTTTCTAAAACTCCTTTGCATCCATCTGCAGCCGGTGGACCAGGCGGTCCGCTTTCAGTT TATCCCGGTGCGGGTGGCGGCTCCGGCGGCGGTTCAGGATCAAGCGTCGCGAGCCTGACTCCAACGGCTGCTCATAGTGGTA GCCATCTGTTTGGGTTTCCCCCAACTCCCCCTAAAGAGGTCAGCCCAGATCCAAGCACGACCGGCGCCGCTTCCCCTGCATCCA GCTCTGCCGGTGGGAGCGCGGCAAGAGGGGAAGATAAAGATGGAGTGAAATATCAAGTAAGTTTGACAGAATCAATGAAAA TGGAGAGCGGATCTCCTCTCCGGCCCGGGCTTGCCACAATGGGTACTCAACCAGCCACCCATCATCCTATTCCAACATATCCTA GCTACGTTCCCGCCGCCGCTCATGATTATTCATCTGGTCTGTTTCATCCTGGCGGGTTCTTGGGCGGCCCCGCGAGCAGTTTTA CACCCAAACAACGTTCTAAAGCCAGGAGCTGCAGTGAGGGTAGAGAATGCGTTAATTGCGGCGCTACTGCAACACCGCTTTG GCGAAGAGATGGTACTGGTCATTATTTGTGTAACGCATGCGGTCTGTATCATAAAATGAACGGTCAAAATCGGCCCCTGATTA AACCTAAAAGGCGGCTTAGTGCGGCAAGGCGTGCAGGAACTTGCTGCGCCAACTGCCAAACAACGACAACTACTCTCTGGAG ACGGAATGCAAATGGTGATCCGGTTTGTAATGCGTGCGGGCTGTATTATAAATTGCATAACGTCAATCGGCCGCTTACAATGA AGAAAGAGGGAATACAAACCAGAAATCGCAAAATGAGCAATAAATCTAAGAAATCTAAGAAGGGAGCAGAATGTTTTGAGG AACTCAGCAAATGTATGCAAGAAAAGTCCAGCCCTTTCTCCGCTGCAGCTTTGGCGGGGCATATGGCTCCCGTCGGTCATCTTC CACCGTTTTCTCATAGCGGTCATATTCTTCCTACGCCCACCCCAATACATCCTTCTTCATCTTTGTCATTTGGACATCCTCATCCAT CTTCTATGGTCACTGCAATGGGCGGCAGCGGCGCCACAAACTTCTCTCTGCTAAAGCAAGCAGGTGATGTTGAAGAAAACCCC GGGCCTATGATGTTTTCAGGGTTTAATGCCGATTATGAAGCCAGTTCTTCAAGATGTTCCTCAGCTTCCCCCGCAGGCGACTCC TTGTCCTATTATCATTCTCCAGCTGATAGCTTTAGTTCCATGGGGTCCCCCGTTAATGCCCAAGACTTTTGTACTGATCTCGCGGT TAGCAGCGCAAATTTTATACCGACTGTGACAGCAATATCAACATCTCCAGATCTTCAATGGCTCGTTCAACCTGCACTGGTGAG CTCTGTCGCACCTTCACAAACGCGGGCTCCACATCCATTTGGCGTTCCTGCACCAAGTGCAGGTGCCTATAGCCGCGCAGGGG TGGTTAAAACAATGACTGGTGGAAGAGCCCAATCCATCGGGCGCCGGGGAAAAGTAGAGCAACTGTCCCCCGAGGAAGAGG AAAAGCGTCGTATTAGGCGCGAGCGGAACAAAATGGCGGCTGCAAAGTGTAGAAATAGGCGCCGCGAATTGACAGACACCC TGCAGGCAGAAACCGATCAGCTCGAGGACGAAAAGTCCGCCCTTCAAACTGAAATCGCAAATTTGCTTAAAGAGAAAGAGAA GTTGGAATTTATACTCGCTGCCCATCGGCCAGCATGTAAAATACCCGACGATTTGGGTTTTCCCGAGGAAATGTCAGTAGCCTC TCTCGACCTTACGGGCGGACTTCCCGAAGTGGCGACTCCTGAAAGTGAAGAAGCATTTACACTTCCCCTGCTGAACGATCCAG AACCTAAACCTTCCGTCGAGCCCGTAAAATCAATTTCTTCCATGGAATTGAAAACAGAACCTTTCGACGATTTTCTCTTTCCTGC CAGTTCACGCCCATCCGGGAGTGAAACCGCTCGAAGCGTTCCGGATATGGATCTTAGCGGCAGCTTTTACGCTGCTGATTGGG AACCGCTTCATAGCGGGTCATTGGGTATGGGACCAATGGCTACCGAACTTGAACCATTGTGTACCCCAGTTGTGACATGCACC CCTTCTTGTACCGCGTATACTTCAAGCTTTGTATTTACATATCCTGAAGCCGATTCATTTCCAAGTTGCGCCGCCGCTCATAGGA AAGGGTCTAGTAGTAACGAACCAAGTTCAGATTCACTGTCCAGCCCTACATTGTTGGCTCTCGGCTCCGGCGAGGGCAGGGGA AGTCTTCTAACATGCGGGGACGTGGAGGAAAATCCCGGCCCAATGCCCCGGAGTTTTCTTGTTAAATCCAAGAAAGCCCATAC ATATCATCAACCTCGCGTCCAAGAGGACGAGCCACTGTGGCCCCCAGCTCTGACGCCTGTACCTCGGGATCAAGCACCGTCTA ATTCTCCCGTGCTGTCAACCCTGTTTCCTAATCAATGTCTTGATTGGACTAATCTTAAGCGCGAACCAGAACTCGAACAAGATCA AAATCTGGCACGGATGGCTCCTGCCCCCGAAGGACCAATCGTACTCTCTCGGCCTCAAGACGGCGATAGTCCCTTGTCAGATTC ACCCCCATTTTATAAACCATCCTTTAGTTGGGATACACTCGCTACTACATACGGTCATTCATATAGACAAGCTCCATCTACAATG CAATCCGCGTTTCTCGAACATAGCGTGAGTCTTTATGGTAGCCCACTGGTTCCAAGTACCGAACCGGCACTGGATTTCTCACTT CGTTATAGCCCTGGGATGGACGCTTATCATTGCGTCAAATGTAATAAAGTGTTTAGTACGCCCCATGGACTGGAAGTCCACGT AAGGCGGAGTCACTCCGGCACTAGACCTTTTGCATGCGATATATGTGGGAAGACTTTTGGTCATGCCGTTTCCCTTGAACAACA TACTCATGTGCATTCTCAAGAAAGATCCTTTGAATGTCGGATGTGTGGAAAAGCATTTAAAAGGTCATCAACTCTCAGCACTCA TTTGCTGATTCATTCTGATACCCGCCCATATCCTTGTCAATTTTGTGGTAAAAGGTTTCATCAGAAAAGCGATATGAAGAAACAT ACCTACATTCATACTGGAGAGAAGCCCCATAAATGTCAAGTTTGTGGTAAGGCATTTTCACAATCTTCTAACCTGATAACACATT CCCGGAAACATACTGGATTTAAACCATTTTCTTGCGAACTCTGTACAAAGGGTTTTCAAAGAAAAGTAGATCTCCGTAGGCATC GTGAATCACAACATAACCTGAAATAA SEQIDNo.46-GiGaFo ATGCCCAGAAGCTTTCTCGTCAAATCAAAGAAAGCCCATACATATCATCAACCTCGGGTTCAAGAGGACGAGCCTTTGTGGCC ACCAGCTCTCACACCAGTCCCTCGGGATCAAGCCCCTTCAAATAGTCCAGTACTCTCTACACTCTTTCCTAATCAATGTTTGGATT GGACAAATCTGAAGCGGGAACCAGAACTTGAACAAGATCAAAATCTGGCACGGATGGCACCTGCGCCTGAAGGACCAATCGT CTTGTCTAGGCCTCAAGACGGCGATAGCCCGCTCAGCGATTCCCCACCGTTTTATAAACCCAGTTTTAGCTGGGATACACTGGC TACGACATACGGACATTCATATAGGCAAGCTCCTAGTACTATGCAATCCGCATTTCTCGAACATAGCGTGTCTTTGTATGGGAG CCCGCTCGTACCTTCTACCGAACCTGCGCTGGATTTTAGTCTGCGTTATAGCCCTGGGATGGACGCCTATCATTGCGTCAAATG TAATAAAGTCTTTAGCACTCCCCATGGCCTGGAAGTCCACGTCCGGCGAAGTCACTCTGGTACTAGACCATTTGCTTGCGATAT TTGTGGAAAGACTTTTGGACATGCCGTCAGTCTTGAACAACATACACATGTGCATTCTCAAGAACGGTCCTTTGAATGTCGGAT GTGTGGGAAAGCTTTTAAAAGAAGCTCTACTCTCTCAACGCATCTCTTGATTCATAGCGATACACGTCCTTATCCATGTCAATTT TGTGGAAAACGCTTCCATCAAAAGTCAGATATGAAGAAACATACTTATATTCATACTGGCGAGAAACCACACAAATGTCAAGT TTGCGGCAAAGCATTTTCCCAATCCTCAAATCTGATTACTCATTCCAGAAAACATACTGGGTTTAAACCATTTTCCTGCGAACTT TGTACGAAGGGTTTTCAAAGGAAAGTTGATTTGCGACGCCATAGAGAATCCCAACATAACCTGAAAGGCAGCGGCGCCACAA ACTTCTCTCTGCTAAAGCAAGCAGGTGATGTTGAAGAAAACCCCGGGCCTATGGAAGTTGCCCCTGAACAACCAAGATGGATG GCCCATCCCGCGGTCCTCAACGCCCAACATCCAGATTCTCATCATCCCGGTCTTGCCCATAATTATATGGAGCCTGCCCAACTTT TGCCCCCAGATGAAGTAGATGTATTCTTCAACCATCTGGATTCCCAAGGAAATCCTTATTACGCAAATCCAGCCCATGCACGCG CCAGGGTGAGCTATTCTCCAGCCCATGCAAGGCTTACGGGCGGACAAATGTGTAGACCTCATCTGCTCCATAGTCCAGGCCTG CCATGGCTTGATGGCGGTAAGGCCGCGCTTAGCGCTGCAGCAGCTCATCATCATAATCCATGGACTGTCTCCCCATTTAGCAAA ACACCGCTTCATCCTTCTGCAGCAGGTGGGCCGGGCGGACCTCTGAGCGTATATCCTGGCGCAGGTGGCGGCTCCGGCGGCG GGTCAGGAAGTAGTGTCGCGAGCCTGACTCCAACCGCTGCTCATAGCGGGAGTCATCTGTTTGGGTTTCCGCCAACACCCCCT AAAGAGGTATCCCCAGATCCATCTACTACCGGTGCCGCCAGTCCCGCAAGCTCCAGTGCAGGCGGCAGCGCTGCTAGAGGTG AAGATAAAGATGGGGTGAAATATCAAGTTTCCCTCACCGAAAGTATGAAAATGGAGTCCGGAAGCCCACTTCGACCTGGTCTT GCCACCATGGGAACACAACCCGCCACCCATCATCCTATACCAACGTATCCAAGCTACGTCCCCGCTGCAGCTCATGATTATTCAT CAGGGCTGTTTCATCCTGGTGGATTCTTGGGCGGTCCTGCTTCAAGTTTTACTCCGAAACAACGGTCTAAAGCCAGGAGCTGCT CCGAGGGAAGGGAATGCGTGAATTGCGGAGCAACCGCTACTCCCCTTTGGCGAAGGGATGGTACTGGTCATTATCTTTGTAAC GCATGCGGGCTGTATCATAAAATGAACGGCCAAAATCGGCCCCTGATTAAACCAAAACGGAGACTTTCCGCTGCACGGCGTGC TGGGACATGCTGCGCTAACTGCCAAACCACCACTACAACTCTCTGGCGGCGGAATGCTAATGGTGATCCAGTGTGTAATGCTT GCGGGCTGTATTACAAACTTCATAACGTGAATCGCCCTCTTACGATGAAGAAAGAGGGAATTCAAACGCGTAATCGTAAAATG TCAAATAAATCAAAGAAATCTAAGAAGGGTGCTGAATGTTTTGAGGAACTCAGCAAATGTATGCAAGAGAAAAGCAGCCCTTT TAGCGCGGCGGCGCTTGCAGGGCATATGGCCCCAGTAGGTCATCTGCCCCCGTTTTCTCATAGCGGTCATATTCTCCCAACCCC AACACCGATACATCCAAGCAGCTCCTTGTCTTTTGGGCATCCTCATCCAAGCTCAATGGTCACAGCAATGGGCGGCTCCGGCGA GGGCAGGGGAAGTCTTCTAACATGCGGGGACGTGGAGGAAAATCCCGGCCCAATGATGTTTTCAGGGTTTAATGCCGATTAT GAAGCCAGTTCATCTCGATGTTCATCAGCCAGCCCTGCTGGCGACTCACTGAGCTATTATCATTCTCCAGCTGATTCATTTTCTT CTATGGGGAGCCCAGTAAATGCACAAGACTTTTGTACCGATCTCGCAGTTTCAAGCGCGAATTTTATCCCAACCGTGACCGCTA TTAGCACTTCTCCAGATCTCCAATGGCTTGTCCAACCGGCTCTGGTGAGTAGCGTCGCTCCGAGCCAAACGAGGGCACCCCATC CGTTTGGTGTACCAGCACCAAGCGCAGGAGCATATTCTCGCGCGGGTGTAGTCAAAACAATGACTGGCGGGCGCGCCCAAAG TATCGGTCGCAGAGGTAAAGTAGAGCAACTGAGCCCCGAGGAAGAGGAAAAGCGACGGATTAGACGTGAGCGGAACAAAAT GGCCGCCGCTAAGTGTCGGAATAGACGACGAGAACTTACAGACACTCTGCAGGCCGAAACCGATCAGTTGGAAGACGAAAA GTCCGCACTCCAAACAGAAATCGCGAATCTTTTGAAAGAGAAAGAGAAGCTCGAATTTATTCTTGCCGCACATCGCCCCGCGT GTAAAATACCCGACGATCTTGGATTTCCTGAGGAAATGTCCGTTGCAAGCCTGGACCTCACCGGCGGACTTCCGGAAGTCGCA ACACCCGAAAGTGAAGAAGCTTTTACTCTTCCCCTGCTGAACGATCCCGAACCTAAACCTTCTGTTGAGCCCGTTAAATCAATA AGTAGTATGGAACTCAAAACTGAACCATTCGACGATTTTCTGTTTCCCGCTTCCAGTAGACCAAGCGGGAGCGAAACTGCACG ATCTGTCCCGGATATGGATCTGTCAGGCTCATTTTACGCGGCCGATTGGGAACCACTCCATTCCGGATCTCTCGGCATGGGACC AATGGCTACCGAACTTGAACCACTTTGTACCCCCGTCGTAACGTGCACACCATCCTGTACCGCGTATACTAGCTCTTTTGTATTT ACTTATCCGGAAGCGGATTCATTTCCAAGTTGCGCCGCCGCTCATAGAAAAGGGTCTTCATCTAACGAACCGTCTTCCGATTCC CTGAGTAGTCCTACCCTTTTGGCATTGTAA SEQIDNo.47-GiFoGa ATGCCGAGATCATTTCTCGTCAAAAGTAAGAAGGCGCATACTTATCATCAACCTCGCGTTCAAGAGGACGAGCCCTTGTGGCC CCCAGCGTTGACACCTGTTCCTCGCGATCAAGCACCCTCTAATAGTCCCGTGCTCTCAACCCTGTTTCCTAATCAATGTTTGGAT TGGACAAATCTGAAGCGTGAACCTGAATTGGAACAAGATCAAAATCTTGCACGCATGGCGCCAGCGCCTGAAGGTCCAATCGT CCTCAGTAGACCACAAGACGGAGATAGCCCGTTGAGCGATTCTCCACCCTTTTATAAACCATCCTTTAGTTGGGATACACTGGC AACGACATACGGACATAGTTATAGGCAAGCTCCATCTACTATGCAATCTGCGTTTCTGGAACATAGCGTTTCTCTTTATGGGTCT CCGCTGGTTCCATCAACAGAACCTGCGCTGGATTTTAGCCTGAGATATAGTCCTGGGATGGACGCATATCATTGCGTAAAATGT AATAAAGTGTTTAGCACACCACATGGCCTGGAAGTCCACGTTCGGCGGAGCCACAGCGGCACAAGGCCATTTGCATGCGATAT TTGTGGGAAGACGTTTGGACATGCCGTTTCCCTCGAACAACATACACATGTTCATAGCCAAGAAAGATCATTTGAATGTAGAAT GTGTGGGAAAGCATTTAAACGGTCTAGCACACTCTCTACGCATCTCCTGATTCATAGCGATACTCGCCCATATCCTTGTCAATTT TGCGGGAAAAGATTTCATCAAAAGTCAGATATGAAGAAGCATACGTATATTCATACCGGGGAGAAACCACATAAATGTCAAGT CTGTGGCAAAGCCTTTTCCCAGTCATCTAATTTGATAACACATAGTAGGAAACATACCGGTTTTAAACCGTTTTCTTGCGAACTC TGTACAAAGGGTTTTCAAAGAAAAGTTGATCTCCGTAGACATAGGGAATCCCAACATAACCTGAAAGGCAGCGGCGCCACAA ACTTCTCTCTGCTAAAGCAAGCAGGTGATGTTGAAGAAAACCCCGGGCCTATGATGTTTAGCGGATTTAATGCCGATTATGAA GCAAGCTCAAGCAGGTGTTCCTCAGCTTCTCCCGCTGGAGACTCTCTGTCATATTATCATAGCCCAGCCGATAGCTTTTCTTCCA TGGGTTCCCCAGTTAATGCTCAAGATTTCTGTACCGATCTCGCGGTGAGTAGCGCAAATTTTATACCAACCGTGACCGCTATTTC TACATCTCCCGATCTTCAATGGTTGGTCCAACCTGCTCTGGTGAGTTCTGTCGCACCCTCTCAAACTCGGGCACCGCATCCCTTT GGCGTACCAGCACCAAGCGCCGGAGCCTATAGCCGGGCAGGGGTGGTCAAAACTATGACCGGTGGGCGTGCCCAATCCATA GGACGCCGCGGGAAAGTCGAGCAATTGAGCCCGGAAGAAGAGGAAAAGCGGCGCATTCGCCGGGAGCGAAACAAAATGGC CGCCGCTAAGTGTCGTAATAGACGCCGCGAACTCACCGACACGTTGCAGGCTGAAACCGATCAGCTCGAGGACGAGAAAAGT GCGCTCCAAACGGAAATCGCTAATCTTCTCAAAGAAAAGGAGAAGCTTGAATTTATTTTGGCCGCCCATCGCCCCGCTTGTAAA ATACCGGACGATCTTGGGTTTCCCGAGGAAATGAGTGTCGCCTCTCTGGACCTCACCGGCGGATTGCCTGAAGTGGCTACACC AGAATCCGAAGAAGCGTTTACGCTCCCCCTGCTGAACGATCCCGAACCAAAACCATCCGTTGAGCCAGTGAAATCAATATCATC CATGGAACTTAAAACAGAACCTTTCGACGATTTTCTGTTTCCTGCCAGCTCACGCCCGAGCGGTTCAGAAACCGCGAGGTCTGT ACCCGATATGGATCTGTCAGGTTCATTTTACGCTGCCGATTGGGAACCCTTGCATAGCGGTTCTTTGGGCATGGGACCTATGGC TACCGAACTCGAACCTCTCTGTACACCTGTCGTGACATGCACACCTTCTTGTACCGCCTATACCTCAAGTTTTGTGTTTACTTATC CAGAAGCCGATAGCTTTCCTAGTTGCGCTGCCGCACATCGTAAAGGAAGTTCCTCAAACGAACCGAGTTCCGATTCTCTTAGTA GCCCAACCCTTTTGGCACTTGGCTCCGGCGAGGGCAGGGGAAGTCTTCTAACATGCGGGGACGTGGAGGAAAATCCCGGCCC AATGGAAGTCGCCCCAGAACAACCTAGGTGGATGGCCCATCCTGCAGTACTCAACGCCCAACATCCTGATAGTCATCATCCCG GATTGGCACATAATTATATGGAGCCGGCTCAACTCCTTCCCCCGGATGAAGTCGATGTTTTCTTTAACCATTTGGATAGTCAAG GAAATCCATATTACGCGAATCCTGCCCATGCCCGTGCCAGGGTGAGCTATTCCCCTGCCCATGCTAGACTCACTGGTGGTCAAA TGTGTAGGCCCCATCTTCTCCATTCCCCTGGACTGCCTTGGTTGGATGGCGGAAAGGCTGCTCTGTCCGCTGCCGCCGCACATC ATCATAATCCTTGGACAGTCAGTCCTTTTAGCAAAACACCACTCCATCCTTCTGCTGCCGGCGGACCCGGCGGTCCTCTGTCAGT TTATCCGGGCGCTGGTGGCGGCTCTGGTGGTGGATCAGGTTCTTCCGTCGCAAGCCTGACTCCCACTGCCGCGCATTCCGGTA GCCATCTCTTTGGTTTTCCCCCTACACCCCCAAAGGAAGTCTCCCCCGATCCCTCAACTACTGGCGCGGCTAGTCCTGCGTCCTC TTCTGCCGGCGGCAGCGCTGCTCGCGGTGAAGATAAAGATGGAGTGAAATATCAAGTTAGCCTCACCGAATCTATGAAAATG GAGAGCGGATCTCCTTTGCGTCCCGGGTTGGCCACCATGGGTACACAACCAGCCACCCATCATCCTATTCCTACTTATCCGAGC TACGTACCTGCTGCCGCACATGATTATTCATCTGGGCTGTTTCATCCAGGCGGGTTTCTCGGTGGCCCCGCAAGCTCATTTACTC CCAAACAAAGGTCCAAAGCGCGGAGCTGCAGTGAGGGGAGAGAATGCGTGAATTGCGGCGCAACCGCTACGCCCTTGTGGA GAAGGGATGGAACGGGGCATTATCTCTGTAACGCATGCGGGTTGTATCATAAAATGAACGGCCAAAATCGCCCCTTGATAAA ACCAAAGAGACGGTTGTCAGCTGCACGACGCGCTGGAACTTGCTGCGCCAACTGCCAAACCACCACAACAACATTGTGGCGG CGTAATGCAAATGGCGATCCCGTGTGTAATGCTTGCGGTCTGTATTATAAATTGCATAACGTGAATAGACCCCTCACTATGAAG AAAGAGGGCATACAAACCCGCAATCGCAAAATGTCAAATAAAAGCAAGAAGTCTAAGAAGGGCGCCGAATGTTTTGAAGAAT TGTCTAAATGTATGCAAGAAAAGAGCAGCCCATTTTCCGCCGCCGCACTCGCAGGCCATATGGCCCCAGTAGGTCATCTGCCCC CTTTTAGTCATAGCGGGCATATTTTGCCTACGCCAACACCGATTCATCCTAGCAGCTCACTGTCTTTTGGGCATCCACATCCAAG TTCTATGGTCACGGCTATGGGTTGA SEQIDNo.48-FoGaGi ATGATGTTTTCAGGATTTAATGCTGATTATGAAGCCAGCTCTAGTAGGTGTTCCTCTGCAAGCCCAGCTGGTGACTCCCTGTCA TATTATCATAGTCCTGCTGATAGCTTTAGTTCTATGGGATCTCCAGTGAATGCCCAAGACTTTTGTACAGATCTCGCAGTAAGCA GCGCAAATTTTATCCCGACTGTTACCGCTATTTCCACTTCACCCGATCTCCAATGGCTTGTCCAACCAGCGCTGGTGAGTAGTGT TGCTCCGAGCCAAACACGGGCTCCCCATCCCTTTGGGGTGCCTGCTCCGAGCGCAGGCGCATATAGCCGTGCCGGAGTGGTG AAAACAATGACCGGCGGACGGGCACAATCTATCGGGCGTAGAGGTAAAGTCGAGCAACTGAGTCCTGAGGAAGAGGAAAAG AGACGGATTAGGCGGGAGCGCAACAAAATGGCAGCCGCAAAGTGTCGAAATAGAAGACGCGAACTCACGGACACCCTGCAG GCAGAAACTGATCAGCTTGAGGACGAAAAGAGTGCCCTGCAAACTGAAATCGCAAATCTTCTCAAAGAAAAGGAGAAGCTGG AATTTATTCTCGCCGCACATAGGCCCGCTTGTAAAATTCCCGACGATCTCGGATTTCCTGAGGAAATGAGCGTTGCCTCACTGG ACCTTACAGGCGGGTTGCCCGAAGTGGCTACTCCCGAATCAGAAGAAGCATTTACTCTTCCCCTGCTGAACGATCCCGAACCAA AACCATCCGTTGAGCCGGTGAAATCTATTAGTTCAATGGAATTGAAAACTGAACCTTTCGACGATTTTCTCTTTCCTGCCTCTAG CCGACCATCAGGGTCCGAAACGGCTCGTAGTGTACCTGATATGGATCTGAGCGGTAGCTTTTACGCCGCCGATTGGGAACCTC TCCATTCCGGTTCATTGGGCATGGGACCGATGGCTACTGAATTGGAACCGCTCTGTACCCCAGTAGTGACATGCACACCTTCAT GTACAGCATATACATCAAGCTTTGTGTTTACTTATCCGGAAGCCGATTCTTTTCCTTCTTGCGCTGCCGCTCATAGGAAAGGCTC CTCTTCTAACGAACCAAGTAGTGATTCACTGTCATCCCCTACACTTTTGGCTCTTGGCAGCGGCGCCACAAACTTCTCTCTGCTA AAGCAAGCAGGTGATGTTGAAGAAAACCCCGGGCCTATGGAAGTAGCCCCTGAACAACCCAGATGGATGGCTCATCCAGCAG TATTGAACGCACAACATCCAGATTCCCATCATCCAGGATTGGCCCATAATTATATGGAGCCAGCCCAACTCTTGCCACCTGATG AAGTCGATGTTTTCTTTAACCATCTGGATAGTCAAGGTAATCCTTATTACGCTAATCCAGCACATGCACGCGCTCGGGTTTCATA TTCCCCTGCCCATGCAAGGCTTACAGGCGGACAAATGTGTCGTCCTCATCTGCTCCATTCCCCAGGCCTTCCATGGCTTGATGG CGGGAAGGCGGCGCTTTCAGCGGCGGCTGCACATCATCATAATCCGTGGACTGTCTCTCCTTTTAGTAAAACTCCGCTTCATCC GAGCGCAGCAGGCGGACCTGGCGGACCCCTGTCAGTCTATCCTGGTGCCGGTGGCGGCTCCGGCGGTGGGTCCGGTTCCAGC GTTGCAAGCTTGACACCAACGGCGGCTCATTCAGGATCACATTTGTTTGGTTTTCCCCCAACCCCGCCGAAAGAGGTCAGTCCC GATCCAAGTACAACCGGAGCAGCAAGTCCCGCAAGCTCATCTGCCGGCGGCTCCGCCGCTAGAGGCGAAGATAAAGATGGG GTAAAATATCAAGTCTCTCTTACCGAATCCATGAAAATGGAGTCTGGATCTCCTCTCCGGCCCGGGCTCGCGACCATGGGGAC ACAACCCGCAACCCATCATCCAATTCCAACTTATCCAAGCTACGTTCCCGCTGCAGCACATGATTATTCATCTGGGCTGTTTCAT CCGGGCGGATTTCTCGGTGGCCCAGCATCTTCTTTTACTCCCAAACAACGGTCTAAAGCAAGGTCTTGCAGTGAGGGTAGGGA ATGCGTGAATTGCGGAGCTACTGCAACTCCCCTGTGGCGTCGCGATGGGACAGGTCATTATCTTTGTAACGCTTGCGGACTTTA TCATAAAATGAACGGCCAAAATCGCCCGCTGATTAAACCTAAACGCAGGTTGTCAGCGGCTCGCAGGGGGGGGACATGCTGC GCCAACTGCCAAACCACCACTACAACACTGTGGCGAAGAAATGCAAATGGCGATCCCGTGTGTAATGCTTGCGGGCTTTATTA TAAACTCCATAACGTCAATCGGCCTCTTACAATGAAGAAAGAGGGAATTCAAACCAGGAATAGGAAAATGTCAAATAAAAGCA AGAAATCAAAGAAGGGCGCCGAATGTTTTGAAGAATTGTCTAAATGTATGCAAGAGAAATCTTCACCGTTTTCCGCCGCCGCG TTGGCCGGTCATATGGCTCCAGTCGGACATCTTCCGCCATTTTCACATAGTGGGCATATTCTTCCAACACCCACACCTATTCATC CTTCATCTTCTCTGTCATTTGGACATCCTCATCCTAGCTCCATGGTTACTGCAATGGGCGGCTCCGGCGAGGGCAGGGGAAGTC TTCTAACATGCGGGGACGTGGAGGAAAATCCCGGCCCAATGCCCCGAAGTTTTCTCGTTAAATCAAAGAAAGCACATACTTAT CATCAACCTCGCGTCCAAGAGGACGAGCCACTTTGGCCACCCGCTCTGACACCTGTCCCGAGGGATCAAGCGCCGTCCAATTC ACCCGTGTTGTCTACCCTCTTTCCCAATCAATGTTTGGATTGGACAAATTTGAAGAGGGAACCAGAACTTGAACAAGATCAAAA TCTTGCGCGGATGGCGCCTGCCCCGGAAGGGCCAATCGTCCTCAGCCGGCCGCAAGACGGCGATTCCCCTCTTAGCGATAGCC CACCATTTTATAAACCCAGTTTTAGCTGGGATACTCTGGCTACTACTTACGGACATTCATATAGACAAGCGCCTTCAACGATGCA AAGCGCATTTCTTGAACATAGTGTGTCCCTTTATGGTTCCCCACTCGTTCCTTCCACAGAACCAGCTCTGGATTTCTCACTTCGAT ATTCTCCCGGGATGGACGCTTATCATTGCGTAAAATGTAATAAAGTGTTTTCTACACCGCATGGTCTGGAAGTCCACGTACGCC GTAGTCACTCCGGCACAAGGCCTTTTGCGTGCGATATTTGTGGGAAGACGTTTGGTCATGCCGTATCACTCGAACAACATACAC ATGTGCATTCTCAAGAACGGAGTTTTGAATGTAGAATGTGTGGTAAAGCTTTTAAAAGGTCATCAACTTTGAGTACTCATCTCT TGATACACAGCGATACAAGGCCGTATCCATGTCAATTTTGTGGAAAACGGTTTCATCAAAAGTCAGATATGAAGAAACATACA TATATTCATACCGGGGAAAAGCCCCATAAATGTCAAGTCTGTGGTAAAGCGTTTTCTCAATCTAGTAATCTGATTACACATTCTC GTAAACATACTGGGTTTAAACCTTTCTCTTGCGAACTTTGTACAAAGGGATTTCAACGGAAAGTCGATCTTCGTAGACATAGAG AATCCCAACATAACCTTAAATAA SEQIDNo.49-FoGiGa ATGATGTTTAGCGGATTTAATGCCGATTATGAAGCAAGCTCATCTCGATGTTCATCTGCAAGCCCAGCTGGTGACTCACTGAGC TATTATCATAGCCCGGCTGATTCATTTTCATCTATGGGTTCCCCCGTTAATGCCCAAGACTTTTGTACCGATCTCGCAGTGAGCA GCGCAAATTTTATCCCTACCGTGACCGCTATATCAACTAGCCCCGATTTGCAATGGCTTGTCCAACCAGCGTTGGTGTCAAGCG TTGCACCCAGCCAAACTCGCGCTCCCCATCCCTTTGGCGTGCCAGCTCCGAGCGCAGGCGCCTATTCACGGGCAGGGGTAGTC AAAACAATGACCGGCGGACGCGCTCAATCCATCGGAAGAAGAGGGAAAGTCGAGCAACTCTCCCCCGAGGAAGAGGAAAAG CGACGCATTAGAAGAGAGCGGAACAAAATGGCCGCCGCTAAGTGTCGGAATAGACGCCGCGAACTCACCGACACTCTGCAGG CCGAAACCGATCAGCTGGAAGACGAAAAGAGTGCCCTTCAAACTGAAATCGCAAATCTCTTGAAAGAAAAGGAGAAGCTGGA ATTTATTCTTGCTGCACATCGTCCAGCATGTAAAATTCCGGACGATTTGGGGTTTCCCGAGGAAATGTCCGTTGCCTCTCTCGAC TTGACCGGTGGGTTGCCTGAAGTAGCTACACCCGAAAGTGAAGAAGCGTTTACTCTTCCATTGCTTAACGATCCAGAACCAAA ACCAAGCGTTGAGCCCGTAAAATCTATTTCTTCAATGGAACTCAAAACTGAACCATTCGACGATTTTCTCTTTCCTGCTTCTAGT AGACCATCTGGCTCCGAAACCGCACGATCTGTACCTGATATGGATCTGTCCGGAAGCTTTTACGCCGCCGATTGGGAACCACTC CATTCCGGTTCACTCGGAATGGGACCTATGGCTACGGAATTGGAACCTCTTTGTACCCCAGTTGTAACTTGCACCCCATCATGT ACCGCCTATACCTCTAGCTTTGTATTTACGTATCCTGAAGCCGATAGCTTTCCATCTTGCGCCGCCGCGCATAGGAAAGGATCTT CAAGTAACGAACCCAGTTCCGATAGTTTGAGTTCTCCGACACTTCTCGCTCTTGGCAGCGGCGCCACAAACTTCTCTCTGCTAA AGCAAGCAGGTGATGTTGAAGAAAACCCCGGGCCTATGCCCCGTTCTTTCTTGGTAAAATCCAAGAAGGCGCATACATATCAT CAACCACGGGTTCAAGAGGACGAGCCACTGTGGCCGCCAGCTCTGACTCCCGTCCCTCGGGATCAAGCCCCCTCTAATTCTCCC GTGCTGTCAACATTGTTTCCTAATCAATGTTTGGATTGGACTAATCTGAAGCGCGAACCAGAATTGGAACAAGATCAAAATCTC GCTCGGATGGCTCCTGCTCCGGAAGGTCCTATCGTTCTTTCAAGACCACAAGACGGCGATTCACCCCTCTCAGATTCTCCCCCTT TCTATAAACCCAGCTTTAGTTGGGATACTCTGGCAACCACATACGGGCATTCTTATCGCCAAGCGCCAAGCACAATGCAAAGTG CATTTCTCGAACATTCAGTATCTCTTTATGGATCTCCCCTGGTCCCTTCTACCGAACCAGCGCTTGACTTTTCCTTGAGGTATAGT CCCGGGATGGACGCATATCATTGCGTAAAATGTAATAAAGTTTTCAGCACGCCCCATGGATTGGAAGTCCACGTCAGGCGATC TCACTCTGGCACAAGACCTTTTGCATGCGATATTTGTGGTAAGACGTTTGGACATGCCGTTTCACTCGAACAACATACACATGT TCATAGCCAAGAACGTTCATTTGAATGTAGAATGTGTGGAAAAGCATTTAAAAGGAGCTCTACCCTTTCTACACATTTGCTGAT TCATAGCGATACCCGACCTTATCCGTGTCAATTTTGTGGAAAACGATTTCATCAGAAATCAGATATGAAGAAGCATACATATAT ACATACCGGGGAGAAACCCCATAAATGTCAAGTCTGTGGCAAAGCATTTTCTCAATCAAGCAATCTGATTACTCATTCCAGAAA ACATACTGGATTTAAACCCTTTTCATGCGAACTTTGTACTAAGGGATTTCAACGGAAAGTTGATTTGAGGAGACATCGAGAAA GTCAACATAACCTGAAAGGCTCCGGCGAGGGCAGGGGAAGTCTTCTAACATGCGGGGACGTGGAGGAAAATCCCGGCCCAA TGGAAGTTGCCCCGGAACAACCCCGTTGGATGGCCCATCCTGCAGTACTTAACGCCCAACATCCGGATTCCCATCATCCCGGAC TCGCTCATAATTATATGGAGCCGGCTCAACTCTTGCCACCCGATGAAGTCGATGTGTTCTTTAACCATCTGGATTCTCAAGGGA ATCCATATTACGCAAATCCAGCACATGCCCGAGCCAGAGTTAGCTATTCACCTGCCCATGCAAGATTGACTGGTGGACAAATGT GTCGGCCCCATCTGCTCCATTCACCAGGGCTCCCATGGCTTGATGGCGGTAAGGCTGCGCTGAGCGCTGCCGCCGCACATCAT CATAATCCATGGACAGTATCTCCCTTTTCTAAAACTCCCCTTCATCCTTCTGCAGCCGGTGGACCCGGCGGACCTTTGAGTGTTT ATCCTGGCGCAGGCGGCGGTTCCGGCGGCGGGAGTGGAAGCAGTGTCGCGAGTCTGACGCCCACTGCTGCACATTCAGGAA GTCATCTGTTTGGGTTTCCCCCAACTCCACCCAAAGAGGTTTCCCCAGATCCAAGTACAACCGGCGCAGCCAGTCCCGCTTCCT CTAGCGCCGGCGGCTCAGCTGCTAGAGGGGAAGATAAAGATGGTGTTAAATATCAAGTTAGCCTTACTGAATCTATGAAAATG GAGTCAGGGAGCCCGCTCAGACCCGGGCTGGCGACGATGGGTACACAACCGGCCACTCATCATCCTATTCCGACGTATCCGA GTTACGTTCCCGCCGCCGCTCATGATTATTCTTCCGGCCTGTTTCATCCAGGCGGTTTTCTTGGCGGCCCCGCGAGCTCATTTAC GCCCAAACAAAGGAGTAAAGCCAGATCTTGCTCTGAGGGGAGAGAATGCGTGAATTGCGGCGCGACGGCAACTCCCTTGTGG CGCCGCGATGGTACTGGGCATTATCTCTGTAACGCATGCGGATTGTATCATAAAATGAACGGTCAAAATAGGCCTCTGATAAA ACCTAAACGGCGCCTTAGTGCGGCAAGGCGTGCAGGAACATGCTGCGCTAACTGCCAAACAACTACAACTACTTTGTGGCGGC GCAATGCGAATGGTGATCCCGTGTGTAATGCTTGCGGATTGTATTATAAACTCCATAACGTGAATCGTCCTCTCACTATGAAGA AGGAAGGAATTCAAACGCGCAATAGGAAAATGTCTAATAAAAGCAAGAAGTCCAAGAAGGGCGCTGAATGTTTTGAAGAACT CAGCAAATGTATGCAAGAGAAATCCAGTCCATTTTCAGCCGCCGCACTTGCAGGTCATATGGCTCCCGTCGGGCATTTGCCACC GTTTTCCCATAGCGGTCATATTCTCCCAACCCCTACTCCAATACATCCTTCTAGCTCTCTGAGTTTTGGGCATCCTCATCCCAGTT CCATGGTCACAGCGATGGGTTGA