Electroporation appliance comprising an oblong applicator, ring electrodes and a seat for a syringe

Abstract

A dynamic electroporation appliance comprises an oblong isolating applicator (1) with a rounded front part (4) and with two annular electrodes (3) arranged on its front surface at the sides of an intermediate opening (2). The intermediate opening it linked to at least one duct (9) associated with a central seat for a syringe (6) for dispensing pharmacological or aesthetic products or active ingredients. The electrodes (3) are energizable to produce a dynamic electroporation effect on the treated surface.

Claims

1. A dynamic electroporation appliance, comprising an oblong applicator (1) in isolating material and having a rounded front part (4) for vaginal and/or anal introduction and an intermediate part adjoining the rounded front part; two ring electrodes (3) arranged on the front part in a spaced relationship to each other; an impulse generator (12) with programmable voltage and frequency and formed as a command and control generator, said two ring electrodes (3) being connected to said impulse generator (12); a duct extending through a seat (5) provided in a rear part of the applicator and connected with an opening (2) provided in the front part between said two ring electrodes (3); and a needless syringe (6) supported on the seat (5) and having a piston (10), said syringe operating as a manual dispenser of pharmacological or aesthetic products or active ingredients, wherein said impulse generator (12) is powered by batteries or mains (14) and supply impulse electric voltage to said two ring electrodes (3); and wherein said duct is connected with said opening (2) by a radial drain (9), and said opening (2) defining a partial convex discharge area between said two ring electrodes (3) through which a respective product supplied through the radial drain (9) is discharged against a to-be-treatable vaginal or anal surface.

2. The dynamic electroporation appliance according to claim 1, wherein said two ring electrodes are in conductive surgical steel.

3. The dynamic electroporation appliance according to claim 1, wherein said two ring electrodes are in conductive plastic material.

4. The dynamic electroporation appliance according to claim 1, wherein said two ring electrodes are positioned on the applicator for transmitting programmable, in terms of frequency and amplitude, impulses generated by said impulse generator.

5. The dynamic electroporation appliance according to claim 1, wherein said impulse generator produces electrical impulses in short time intervals predefined or adjustable from a display.

6. The dynamic electroporation appliance according to claim 1, wherein a grip (7) is provided in the rear part of the applicator for vaginal or anal introduction of the applicator, emission action of pharmacological or aesthetic products, and withdrawal of the applicator.

7. The dynamic electroporation appliance according to claim 1, wherein at least two circumferential convexes (11) are provided in a central part located between the front and rear parts for calibrating a vaginal or anal introduction depth and for retaining the applicator in a predetermined position, without manual support.

8. The dynamic electroporation appliance according to claim 1, wherein a connector or cables (8) which connect said two ring electrodes (3) with the pulse generator (12) extend through the rear part of the applicator.

Description

(1) The invention is described in detail below, according to one of its embodiments provided in an illustrative and non limitative way, with reference to the attached drawing wherein:

(2) FIG. 1 represents a longitudinal section view of the vaginal and/or anal applicator of the dynamic electroporation appliance, and

(3) FIG. 2 schematically represents the appliance as a whole.

(4) With reference to the illustrations, the appliance substantially consists of an applicator (1) in isolating material rounded in the front part (4) to favour an easy and painless introduction and adherence with the inner vaginal and/or anal wall to be treated. In the front intermediate part, besides the introductive area, the applicator comprises a partial convex area forming a substantially annular opening (2) at the sides of which are arranged two rings (3), in surgical steel or in conductive plastic material, electrically connected to the impulse generator.

(5) In the rear part is a central seat (5) comprising a front coaxial duct with at least a radial drain (9) running into the substantially central area of said convex annular opening (2). In the seat (5) a syringe without needle (6) is positionable, with relative piston (10), designed to contain the pharmaceutical product, the aesthetic product or the active ingredient to be used. By means of the piston (10) the fluid product is pushed along the duct (9) and discharged in the convex annular opening (2) where it can expand and uniformly come into contact with the entire vaginal or anal surface to be treated, included between the electrodes (3) which, supplied by the electric impulse generator, perform the electroporation action needed to favour the uniform and deep transdermal and transmucous vehiculation of the medical substances, including with high molecular weight. In the rear part a grip (7) is provided designed to facilitate the introduction, the positioning, the emission action of the fluid products and the removal of the applicator.

(6) Two circumferential convexes (11) arranged in the central part of the applicator (1) have the purpose of calibrating the introduction depth and make it easier to keep it in position, without supplementary manual supports.

(7) In the rear part (7) of the applicator is also provided the exit of the connector or of the cables (8) for connecting the two electroporation electrodes (3) to a programmable command and control impulse generator (12) with display (13), powered by batteries or from the power mains (14).

(8) The dynamic electroporation appliance is specifically usable for Gynaecological, Aesthetic and Functional applications and for Proctology, in particular and by way of example for: vaginal dryness; vulvar itching; dyspareunia; vulvar-vaginal burning sensation; hyperplastic, atrophic and mixed vulvar dystrophies; craurosi vulvare (lichen sclerosus); dyskeratosis; post-episiotomy scars; urinary incontinence; haemorrhoids; faecal incontinence.

(9) The electroporation impulses produced by the appliance (12) supplying the applicator (1) are programmable in terms of frequency and amplitude depending on the many possible functions.