CO-CRYSTALS OF BOSCALID AND TRIAZOLES

Abstract

The present invention relates to co-crystals of boscalid and a triazole fungicide such as hexaconazole or cyproconazole. Also included are agrochemical compositions and methods of combating or controlling fungi by contacting the fungi or their locus with a fungicidally effective amount of the co-crystal.

Claims

1. A co-crystal of boscalid and hexaconazole or cyproconazole.

2. The co-crystal of claim 1 comprising boscalid and hexaconazole, wherein the melting point of the co-crystal is in the range of 101-105° C. when measured with a Differential Scanning calorimeter.

3. The co-crystal of claim 1 comprising boscalid and cyproconazole, wherein the melting point of the co-crystal is in the range of 97-101° C. when measured with a Differential Scanning calorimeter.

4. The co-crystal of claim 1, where in the molar ratio of boscalid to hexaconazole or cyproconazole is in the range of 3:1 to 1:3.

5. The co-crystal of claim 1, where in the molar ratio of boscalid to hexaconazole or cyproconazole is 1:1.

6. An agrochemical composition comprising the co-crystal of claim 1 and an agronomically acceptable excipient.

7. A method of combating or controlling fungi, said method comprising contacting fungi or their locus with a fungicidally effective amount of the co-crystal of claim 1.

Description

DESCRIPTION OF THE ACCOMPANYING DRAWINGS

[0122] FIG. 1 shows a DSC trace of co-crystal of boscalid and tebuconazole obtained using the process described in Example 1.

[0123] FIG. 2 shows a DSC trace of boscalid and hexaconazole co-crystal obtained using the process described in Example 2.

[0124] FIG. 3 shows a DSC trace of boscalid and cyproconazole co-crystal obtained using the process described in Example 3.

[0125] FIG. 4 shows a DSC trace of co-crystal of boscalid and tebuconazole obtained using the process described in Example 7.

[0126] FIG. 5 shows the HPLC chromatogram of co-crystal of boscalid and tebuconazole obtained using the process described in Example 1.

[0127] While the foregoing written description of the invention enables one of ordinary skill to make and use what is considered presently to be the best mode thereof, those of ordinary skill will understand and appreciate the existence of variations, combinations, and equivalents of the specific embodiment, method, and examples herein. The invention should therefore not be limited by the above described embodiment, method, and examples, but by all embodiments and methods within the scope and spirit of the invention.