VITALITY DIETARY SUPPLEMENT

Abstract

The present invention is directed to improving immune function by improving or increasing the function of immune cells, promoting adequate hydration, and supplying essential nutrients and amino acids that the immune system requires to function. The supplement composition of the present invention comprises: Collagen Peptides, 1-glutamine, 1-arginine, Baker's Yeast Beta Glucan, 1-tryptophan, Heat-Killed Lactobacillus plantarum, vitamins, and minerals. Immune system function is improved using this combination of components.

Claims

1. A dietary supplement composition comprising collagen in an amount of about 7 to 69 weight percent of the composition, 1-glutamine in an amount of about 3 to 31 weight percent of the combination, 1-arginine in an amount of about 0.7 to 8 weight percent of the composition, Baker's Yeast Beta Glucan in an amount of about 0.3 to 4.0 weight percent of the composition, 1-tryptophan in an amount of about 0.1 to 0.8 weight percent of the composition, and Heat-Killed Lactobacillus plantarum L-137 in an amount of about 0.1 to 0.8 weight percent of the composition.

2. The dietary supplement composition of claim 1, wherein the collagen is present in the form of hydrolyzed collagen peptides.

3. The dietary supplement composition of claim 1, wherein the composition further comprises electrolyte minerals and wherein total amount of electrolyte minerals is present in an amount of about 7 to 39 weight percent of the total composition.

4. The dietary supplement composition of claim 1, wherein the composition further comprises vitamins suitable for ingestion in a dietary supplement and wherein each such vitamin is present in an amount of about 0.001-15.4 weight percent of the total composition.

5. The dietary supplement composition according to claim 1, wherein the composition is a powder.

6. The dietary supplement composition according to claim 1, wherein the composition is a liquid.

7. The dietary supplement composition of claim 1, wherein collagen is present in an amount of about 20 to 54 weight percent of the composition, 1-glutamine in an amount of about 7 to 23 weight percent of the combination, 1-arginine in an amount of about 2 to 6 weight percent of the composition, Baker's Yeast Beta Glucan in an amount of about 1 to 3.1 weight percent of the composition, 1-tryptophan in an amount of about 0.2 to 0.6 weight percent of the composition, and Heat-Killed Lactobacillus plantarum L-137 in an amount of about 0.2 to 0.6 weight percent of the composition.

8. The dietary supplement composition of claim 7, wherein the collagen is present in the form of hydrolyzed collagen peptides.

9. The dietary supplement composition of claim 7, wherein the composition further comprises electrolyte minerals and wherein total amount of electrolyte minerals is present in an amount of about 10 to 23 weight percent of the total composition.

10. The dietary supplement composition of claim 7, wherein the composition further comprises vitamins suitable for ingestion in a dietary supplement and wherein each such vitamin is present in an amount of about 3-12 weight percent of the total composition.

11. The dietary supplement composition of claim 7, wherein the composition is a powder.

12. The dietary supplement composition of claim 7, wherein the composition is a liquid.

13. The dietary supplement composition of claim 1, wherein collagen is present in an amount of about 27 to 46 weight percent of the composition, 1-glutamine in an amount of about 10 to 19 weight percent of the combination, 1-arginine in an amount of about 3 to 5 weight percent of the composition, Baker's Yeast Beta Glucan in an amount of about 1.3 to 2 weight percent of the composition, 1-tryptophan in an amount of about 0.3 to 0.5 weight percent of the composition, and (Heat-Killed Lactobacillus plantarum L-137) in an amount of about 0.3 to 0.5 weight percent of the composition.

14. The dietary supplement composition of claim 13, wherein the collagen is present in the form of hydrolyzed collagen peptides.

15. The dietary supplement composition of claim 13, wherein the composition further comprises electrolyte minerals and wherein total amount of electrolyte minerals is present in an amount of about 15 to 21 weight percent of the total composition.

16. The dietary supplement composition of claim 13, wherein the composition further comprises vitamins suitable for ingestion in a dietary supplement and wherein each such vitamin is present in an amount of about 5-10 weight percent of the total composition.

17. The dietary supplement composition of claim 13, wherein the composition is a powder.

18. The dietary supplement composition of claim 13, wherein the composition is a liquid.

19. A dietary supplement composition comprising the following ingredients: TABLE-US-00002 Ingredient Amount per serving % Daily Value Collagen peptides 5 g ** (from bovine) L-Glutamine 2 g ** L-Arginine 500 mg ** Wellmune baker's yeast 250 mg ** beta glucan (from Saccharomyces cerevisiae) L-Tryptophan 50 mg ** Immuno-LP20 50 mg ** (heat-killed Lactobacillus plantarum strain L-137) Vitamin C 1000 mg 1,111%   Vitamin D 20 mcg 100% (as cholecalciferol) Niacin 8 mg 100% (as niacinamide) Vitamin B6 1.7 mg 100% (as pyridoxine HCl) Vitamin B12 4.8 mcg 200% (as cyanocobalamin) Magnesium 50 mg  12% (as magnesium citrate) Zinc 22 mg 200% (as zinc citrate) Sodium 500 mg  22% Potassium 400 mg  9% (as potassium citrate) **Daily Value Not Established

20. A method of improving immune system function comprising administering to a patient in need thereof a composition comprising collagen in an amount of about 7 to 69 weight percent of the composition, 1-glutamine in an amount of about 3 to 31 weight percent of the combination, 1-arginine in an amount of about 0.7 to 8 weight percent of the composition, Baker's Yeast Beta Glucan in an amount of about 0.3 to 4.0 weight percent of the composition, 1-tryptophan in an amount of about 0.1 to 0.8 weight percent of the composition, and Heat-Killed Lactobacillus plantarum L-137 in an amount of about 0.1 to 0.8 weight percent of the composition.

Description

DETAILED DESCRIPTION OF THE INVENTION

[0009] The present invention relates to a dietary supplement composition that may be consumed as a supplement to support and enhance immune system function

[0010] The compositions of the present invention comprise collagen, preferably in the form of hydrolyzed collagen peptides, in combination with 1-glutamine, 1-arginine, Baker's Yeast Beta Glucan, 1-tryptophan, Heat-Killed Lactobacillus plantarum, optionally, additional vitamins and minerals.

[0011] The composition may be administered in the form of a liquid, solution, suspension, powder, or gel. If in powder form, the powder is mixed in a soluble liquid prior to administration as directed.

[0012] Collagen is present in the composition in an amount of about 7 to 69 weight percent of the composition, about 20 to 54 weight percent of the composition, or about 27 to 46 weight percent of the composition. Alternatively, collagen may be present in the composition in an amount of about 1-9 grams/serving, about 3-7 grams/serving, or about 4-6 grams/serving. In a preferred embodiment, collagen may be present in the composition in an amount of about 5 grams/serving. Collagen is a protein and may be present in any available form in the composition. However, the present invention preferably uses collagen peptides. Collagen peptides may be sourced from any known source, including but not limited to, beef, chicken, fish, eggshell membrane, and chicken egg whites.

[0013] L-glutamine is present in the composition in an amount of about 0.5-4.0 g/serving, about 1-3 g/serving, about 1.5-2.5 g/serving, or about 2 g/serving. Alternatively, 1-glutamine may be present in the composition in an amount of about 3-31 weight percent, about 7-23 weight percent, or about 10-19 weight percent.

[0014] L-arginine is also present in the composition in an amount of about 0.1-1 g/serving, about 0.25-0.75 g/serving, about 0.4-0.6 g/serving, or about 0.5 g/serving. Alternatively, 1-arginine may be present in the composition in an amount of about 0.7-8 weight percent, about 2-6 weight percent, or about 3-5 weight percent.

[0015] Baker's Yeast Beta Glucan is also present in the composition in an amount of about 0.05-0.5 g/serving, about 0.15-0.4 g/serving, about 0.2-0.3 g/serving, or about 0.25 g/serving. Alternatively, Baker's Yeast Beta Glucan may be present in the composition in an amount of about 0.3-4.0 weight percent, about 1-3.1 weight percent, or about 1.3-2 weight percent. In a preferred embodiment, Wellmune® Baker's Yeast Beta Glucan is used.

[0016] L-tryptophan is also present in the composition in an amount of about 0.01-0.1 g/serving, about 0.025-0.075 g/serving, about 0.04-0.06 g/serving, or about 0.05 g/serving. Alternatively, I-tryptophan may be present in the composition in an amount of about 0.1-0.8 weight percent, about 0.2-0.6 weight percent, or about 0.3-0.5 weight percent.

[0017] Heat-Killed Lactobacillus plantarum L-137 is also present in the composition in an amount of about 0.01-0.1 g/serving, about 0.025-0.075 g/serving, about 0.04-0.06 g/serving, or about 0.05 g/serving. Alternatively, Heat-Killed Lactobacillus plantarum L-137 may be present in the composition in an amount of about 0.1-0.8 weight percent, about 0.2-0.6 weight percent, or about 0.3-0.5 weight percent. In a preferred embodiment, Immuno-LP20® (Heat-Killed Lactobacillus plantarum L-137) is used.

[0018] Additional nutrients may be used in the composition including electrolytes, vitamins, minerals, and other dietary supplements. Suitable electrolyte minerals include, but are not limited to calcium, sodium, potassium, magnesium, calcium, bicarbonate, chloride, zinc and phosphate. The total amount of electrolyte minerals may be added to the composition in an amount of about 7-39 weight percent of the composition, about 10-23, or about 15-21 weight percent of the composition. Alternatively, the total electrolytes may be present in a range of about 1-5 grams/serving, about 1.5-3 grams/serving, or about 2.25-2.75 grams/serving.

[0019] Sodium may be present in any form, such as sea salt, iodized salt, sodium bicarbonate, or Himalayan pink sea salt, in an amount of about 0.2-1 grams/serving or 0.3-0.7 grams/serving, or about 1.3-8 weight percent or about 2-6 weight percent of the total composition.

[0020] Potassium may be present in any suitable form, such as a potassium citrate, potassium chloride, potassium sorbate, or the like. Potassium may be present in an amount of about 0.1-2 grams/serving or about 0.2-1 grams/serving, or about 0.7-15 or about 1.3-8 weight percent of the total composition.

[0021] Magnesium may be present in any suitable form, such as a magnesium citrate, magnesium oxide, magnesium lysinate-glycinate chelate, or magnesium malate. Magnesium may be present in an amount of about 0.01-0.2 grams/serving or about 0.02-0.1 grams/serving, or about 0.1-1.5 or about 0.1-0.8 weight percent of the total composition.

[0022] Zinc may be present in any suitable form, such as a zinc sulfate or zinc citrate. Zinc may be present in an amount of about 0.01-0.2 grams/serving or about 0.01-0.1 grams/serving, or about 0.1-1.5 or about 0.1-0.8 weight percent of the total composition.

[0023] Vitamins may further be added to the composition. Any vitamins suitable for ingestion in a dietary supplement is suitable for use. Suitable vitamins include but are not limited to Vitamin B, including Vitamin B1 (e.g., as thiamine chloride), Vitamin B2 (e.g., as riboflavin), Vitamin B3 (e.g., niacinamide), Vitamin B6 (e.g., as pyridoxine HCl), Vitamin B5 (e.g., as pantothenic acid or D-calcium pantothenate), Vitamin B12 (cyanocobalamin), folate (e.g., as folic acid), Vitamin C (e.g., as sodium ascorbate), Vitamin D, Vitamin E, etc. In the context of the present invention, each of the vitamins may be independently present in the composition in an amount of about 0.01-2 grams/serving, about 0.5-1.5 grams/serving, about 0.75-1.25 grams/serving, or about 0.001-15.4, about 3-12, or about 5-10 weight percent of the total composition.

[0024] Moreover, the composition may be flavored using any known natural flavors to enhance the flavor of the composition. Additionally, other additives suitable for dietary supplements, including but not limited to, monk fruit extract, Himalayan pink sea salt, fruit and vegetable juice powder, beta-carotene, citric acid, and malic acid

[0025] In accordance with the present invention, suitable compositions include, but are not limited, to those described in Table 1.

TABLE-US-00001 TABLE 1 Ingredient Amount per serving % Daily Value Collagen peptides 5 g ** (from bovine) L-Glutamine 2 g ** L-Arginine 500 mg ** Wellmune baker's yeast 250 mg ** beta glucan (from Saccharomyces cerevisiae) L-Tryptophan 50 mg ** Immuno-LP20 50 mg ** (heat-killed Lactobacillus plantarum strain L-137) Vitamin C 1000 mg 1,111%   Vitamin D 20 mcg 100% (as cholecalciferol) Niacin 8 mg 100% (as niacinamide) Vitamin B6 1.7 mg 100% (as pyridoxine HCl) Vitamin B12 4.8 mcg 200% (as cyanocobalamin) Magnesium 50 mg  12% (as magnesium citrate) Zinc 22 mg 200% (as zinc citrate) Sodium 500 mg  22% Potassium 400 mg  9% (as potassium citrate) Ingredient Amount per serving % Daily Value **Daily Value Not Established

[0026] In an embodiment of the present invention, the caloric intake of the supplement is less than about 100 calories, less than about 75 calories, or about 30 calories per serving. Additionally, the amount of carbohydrates and total sugars in the composition is desirably low. For example, the carbohydrates may be present in an amount of less than 10 grams/serving, less than 7 grams/serving, less than 5 grams/serving, about 2 grams/serving, or about 1 grams/serving. Similarly, the total sugars is desirably kept low, e.g., less than 6 grams/serving, less than 5 grams/serving, or about 0 gram/serving. As noted above, the content of the protein, in the form of collagen or collagen peptides, is high, preferably above 2 grams/serving, above 4 gram/serving, or about 5 grams/serving.

Example 1

[0027] A composition of the formula depicted in Table 1 was prepared.