An Improved Galactose Oxidase Enzyme Panel for Oxidation of Secondary Alcohols

Abstract

Disclosed are modified galactose oxidase variants with enhanced protein expression, solubility, thermal stability, and enzymatic activity, and reduced enantioselectivity compared to wild-type galactose oxidase or galactose oxidase variants known in the art, and methods of producing the same.

Claims

1. A modified galactose oxidase comprising a polypeptide sequence having at least 85%, 86%, 87%, 88%, 89%, 90%, 91%, 92%, 93%, 94%, 95%, 96%, 97%, 98%, or 99% sequence identity to SEQ ID NO: 6, wherein SEQ ID NO: 6 is a polypeptide sequence of galactose oxidase variant M3-5, wherein the galactose oxidase variant M3-5 comprises mutations of S33P, M93V, G218E, W313F, R353M, Q429T, V517A, and N558D relative to the wildtype galactose oxidase from Fusarium graminearum (SEQ ID NO: 4), and wherein the polypeptide sequence of the modified galactose oxidase further comprises at least one mutation at one or more positions selected from the group consisting of 24, 26, 28, 45, 49, 65, 69, 104, 114, 117, 153, 157, 172, 173, 175, 193,194, 195, 197, 198,202, 214, 217, 218, 220, 224, 226, 239, 240, 250, 259, 265, 268, 269, 284, 294, 313, 314, 325, 341, 346, 348, 352, 353, 356, 389, 401, 429, 447, 485, 487, 537, 538, 546, 559, 576, 599, and 662, wherein the position of the mutation is numbered with reference to SEQ ID NO: 6.

2. The modified galactose oxidase of claim 1, wherein the mutation is selected from the group consisting of A24H, A24N, A26H, A26R, I28F, I28M, I28R, Q45D, Q45E, Q45N, E49K, F65P, N69D, N69E, N69F, N69H, N69L, N69M, N69T, N69W, N69Y, W104G, W104N, S114N, S114R, T117D, T153K, T153R, G157N, S172E, S173K, S173R, T175E, T175H, T175I, T175K, V193T, P194C, A195S, A195T, A195V, A197C, A197G, A198I, T202D, T202I, T202K, T202Q, N214R, N214S, F217A, F217C, F217D, F217E, F217G, F217H, F217I, F217K, F217L, F217M, F217N, F217P, F217Q, F217R, F217S, F217T, F217V, F217Y, E218F, E218K, E218P, E218Y, S220T, I224W, L226Q, L226V, D239E, D239P, D239Q, R240G, F250E, F250Y, N259T, T265S, N268W, D269N, I284S, I284Y, G294A, F313R, S314C, Y325F, N341W, A346L, K348S, Y352T, Y352W, M353F, N356K, N356R, N356W, K389I, A401 D, T429W, T447A, I485A, I485K, I485R, F487R, L537G, C538K, C538R, F546M, S559P, S576D, Y599M, Q662D, and Q662P, or the mutation is selected from the group consisting of I28R, A24H, A195S, A195T, A195V, A198I, T202I, F217A, E218F, E218K, L226Q, D239E, N259T, N268W, S314C, Y352W, Y599M, and combinations thereof.

3. (canceled)

4. The modified galactose oxidase of claim 1, wherein the mutation is selected from the group consisting of: M353F; S314C; L537G; F217V; F217P; F217Q; F217N; F217S; N268W; E218P; F217I; F217T; F217L; F217E; F217Y; F217A; F217C; F217D; F217G; F217H; F217K; F217M; F217R; a combination of F217P and E218P; a combination of F217P and L537G; a combination of F217P, E218P and L537G; a combination of F217V and E218P; a combination of F217V and L537G; a combination of F217V, E218P and L537G; a combination of E218P and L537G; a combination of F217A and N268W; a combination of F217A, N268W and M353F; a combination of F217A, N268W and S314C; a combination of F217G and N268W; a combination of F217G, N268W and M353F; a combination of F217A, N268W and A195S; a combination of F217A, N268W and V193T; a combination of F217A, N268W and N259T; a combination of F217A, N268W and Y325F; a combination of F217A, N268W and G294A; a combination of F217A, N268W and A195T; a combination of F217A, N268W and Y352T; a combination of F217A, N268W and N341W; a combination of F217A, N268W and A197C; a combination of F217A, N268W and R240G; a combination of F217A, N268W and A198I; a combination of F217A, N268W and K348S; a combination of F217A, N268W and T202D; a combination of F217A, N268W and T202Q; a combination of F217A, N268W and T202I; a combination of F217A, N268W and T202K; a combination of F217A, N268W and P194C; a combination of F217A, N268W and A346L; a combination of F217A, N268W and K389I; a combination of F217A, N268W and Y352W; a combination of F217A, N268W and C538K; a combination of F217A, N268W and C538R; a combination of F217A, N268W and F250E; a combination of F217A, N268W and F250Y; a combination of F217A, N268W and N356K; a combination of F217A, N268W and N356R; a combination of F217A, N268W and N356W; a combination of F217A, N268W and F487R; a combination of F217A, N268W and T429W; a combination of F217A, N268W and E218K; a combination of F217A, N268W and F313R; a combination of F217A, N268W and I284Y; a combination of F217A, N268W and A24H; a combination of F217A, N268W and I28R; a combination of F217A, N268W and I28M; a combination of F217A, N268W and S576D; a combination of F217A, N268W and I284S; a combination of F217A, N268W and F65P; a combination of F217A, N268W and T153R; a combination of F217A, N268W and A197G; a combination of F217A, N268W and T265S; a combination of F217A, N268W and S220T; a combination of F217A, N268W and N214S; a combination of F217A, N268W and I485A; a combination of F217A, N268W and N214R; a combination of F217A, N268W and D269N; a combination of F217A, N268W and I485R; a combination of F217A, N268W and I485K; a combination of F217A, N268W and D239E; a combination of F217A, N268W and T117D; a combination of F217A, N268W and S114R; a combination of F217A, N268W and S559P; a combination of F217A, N268W and S114N; a combination of F217A, N268W and Q662P; a combination of F217A, N268W and S173R; a combination of F217A, N268W and D239P; a combination of F217A, N268W and S172E; a combination of F217A, N268W and Q662D; a combination of F217A, N268W and S173K; a combination of F217A, N268W and A195V; a combination of F217A, N268W and E218F; a combination of F217A, N268W and L226Q; a combination of F217A, N268W and I224W; a combination of F217A, N268W and A26R; a combination of F217A, N268W and I28F; a combination of F217A, N268W and E218Y; a combination of F217A, N268W and L226V; a combination of F217A, N268W and D239Q; a combination of F217A, N268W and F546M; a combination of F217A, N268W and A24N; a combination of F217A, N268W and A26H; a combination of F217A, N268W and Y599M; a combination of F217A, N268W and G157N; a combination of F217A, N268W and Q45D; a combination of F217A, N268W and Q45E; a combination of F217A, N268W and Q45N; a combination of F217A, N268W and E49K; a combination of F217A, N268W and N69D; a combination of F217A, N268W and N69E; a combination of F217A, N268W and N69F; a combination of F217A, N268W and N69H; a combination of F217A, N268W and N69L; a combination of F217A, N268W and N69M; a combination of F217A, N268W and N69T; a combination of F217A, N268W and N69W; a combination of F217A, N268W and N69Y; a combination of F217A, N268W and W104G; a combination of F217A, N268W and W104N; a combination of F217A, N268W and T175E; a combination of F217A, N268W and T175H; a combination of F217A, N268W and T175I; a combination of F217A, N268W and T175K; a combination of F217A, N268W and A401D; a combination of F217A, N268W, A195T and Y352W; a combination of F217A, N268W, N341W and Y352T; a combination of F217A, N268W, A198I and N259T; a combination of F217A, N268W, A195S and N341W; a combination of F217A, N268W, T153K and A195S; a combination of F217A, N268W, I28R and K389I; a combination of F217A, N268W, T153R and A195T; a combination of F217A, N268W, I28R, T153R, A198I and N341W; a combination of F217A, N268W, A195T, N259T and N341W; a combination of F217A, N268W, I28R, A195T, N259T and K389I; a combination of F217A, N268W, I28R, N259T and N341W; a combination of F217A, N268W, I28R, A195S and K389I; a combination of F217A, N268W, A195T and N341W; a combination of F217A, N268W, I28R, A195T, N341W and K389I; a combination of F217A, N268W, I28R, A195T, N259T and T447A; a combination of F217A, N268W, I28R, A195S, N259T and N341W; a combination of F217A, N268W, I28R, A195T, N259T, N341W and K389I; and a combination of F217A, N268W, T153R and N341W.

5. The modified galactose oxidase of claim 1, wherein the polypeptide sequence of the modified galactose oxidase has at least 85%, 86%, 87%, 88%, 89%, 90%, 91%, 92%, 93%, 94%, 95%, 96%, 97%, 98%, or 99% sequence identity to the sequence of at least one modified galactose oxidase variant set forth in the even numbered sequences of SEQ ID NOS: 7-298, or the polypeptide sequence of the modified galactose oxidase comprises a polypeptide sequence set forth in the even numbered sequences of SEQ ID NOS: 7-298.

6. (canceled)

7. The modified galactose oxidase of claim 1, wherein the mutation is selected from the group consisting of: (a) S314C; (b) N268W; (c) F217A; (d) a combination of F217A and N268W; (e) a combination of F217A, N268W and A195S; (f) a combination of F217A, N268W and N259T; (g) a combination of F217A, N268W and A195T; (h) a combination of F217A, N268W and A198I; (i) a combination of F217A, N268W and T202I; (j) a combination of F217A, N268W and Y352W; (k) a combination of F217A, N268W and A24H; (l) a combination of F217A, N268W and I28R; (m) a combination of F217A, N268W and D239E; (n) a combination of F217A, N268W and A24N; (o) a combination of F217A, N268W and E218K; (p) a combination of F217A, N268W and E218F; (q) a combination of F217A, N268W and Y599M; (r) a combination of F217A, N268W and L226Q; (s) a combination of F217A, N268W and A195V; (t) a combination of F217A, N268W, A195T and Y352W; (u) a combination of F217A, N268W, I28R and K389I; (v) a combination of F217A, N268W, I28R, A195T, N259T, and K389I; and (w) a combination of F217A, N268W, I28R, A195T, N259T, N341W, and K389I.

8. The modified galactose oxidase of claim 1, wherein the modified galactose oxidase comprises the mutations of F217A and N268W, or the polypeptide sequence of the modified galactose oxidase has at least 85%, 86%, 87%, 88%, 89%, 90%, 91%, 92%, 93%, 94%, 95%, 96%, 97%, 98%, or 99% sequence identity to SEQ ID NO:68.

9. (canceled)

10. The modified galactose oxidase of claim 8, wherein the modified galactose oxidase further comprises at least one mutation selected from the group consisting of A24H, A24N, A26H, A26R, I28F, I28M, I28R, Q45D, Q45E, Q45N, E49K, F65P, N69D, N69E, N69F, N69H, N69L, N69M, N69T, N69W, N69Y, W104G, W104N, S114N, S114R, T117D, T153K, T153R, G157N, S172E, S173K, S173R, T175E, T175H, T175I, T175K, V193T, P194C, A195SX, A195T, A195V, A197C, A197G, A198I, T202D, T202I, T202K, T202Q, N214R, N214S, E218F, E218K, E218P, E218Y, S220T, I224W, L226Q, L226V, D239E, D239P, D239Q, R240G, F250E, F250Y, N259T, T265S, D269N, I284S, I284Y, G294A, F313R, S314C, Y325F, N341W, A346L, K348S, Y352T, Y352W, M353F, N356K, N356R, N356W, K389I, A401 D, T429W, T447A, I485A, I485K, I485R, F487R, L537G, C538K, C538R, F546M, S559P, S576D, Y599M, Q662D, and Q662P, wherein the position of the mutation is numbered with reference to SEQ ID NO: 6; or the polypeptide sequence of the modified galactose oxidase has at least 85%, 86%, 87%, 88%, 89%, 90%, 91%, 92%, 93%, 94%, 95%, 96%, 97%, 98%, or 99% sequence identity to the sequence of at least one modified galactose oxidase variant set forth in SEQ ID NOS: 70, 72 or the even numbered sequences of SEQ ID NOS: 77-298, or the polypeptide sequence of the modified galactose oxidase comprises a polypeptide sequence set forth in SEQ ID NOS: 70, 72 or the even numbered sequences of SEQ ID NOS: 77-298.

11.-12. (canceled)

13. The modified galactose oxidase of claim 1, wherein the modified galactose oxidase comprises one or more of the following properties: (a) enhanced protein expression by at least 1.01-fold compared to the galactose oxidase variant M3-5 or by at least 1.01-fold compared to a modified galactose oxidase comprising the mutations of F217A and N268W, or the polypeptide sequence of the modified galactose oxidase has at least 85%, 86%, 87%, 88%, 89%, 90%, 91%, 92%, 93%, 94%, 95%, 96%, 97%, 98%, or 99% sequence identity to SEQ ID NO:68; (b) enhanced solubility by at least 1.01-fold compared to the galactose oxidase variant M3-5 or by at least 1.01-fold compared to a modified galactose oxidase comprising the mutations of F217A and N268W, or the polypeptide sequence of the modified galactose oxidase has at least 85%, 86%, 87%, 88%, 89%, 90%, 91%, 92%, 93%, 94%, 95%, 96%, 97%, 98%, or 99% sequence identity to SEQ ID NO:68; (c) enhanced thermal stability by at least 1.01-fold compared to the galactose oxidase variant M3-5 or by at least 1.01-fold compared to a modified galactose oxidase of claim 8 at a temperature of at least 50 C. comprising the mutations of F217A and N268W, or the polypeptide sequence of the modified galactose oxidase has at least 85%, 86%, 87%, 88%, 89%, 90%, 91%, 92%, 93%, 94%, 95%, 96%, 97%, 98%, or 99% sequence identity to SEQ ID NO:68; (d) increased enzymatic activity by at least 1.01-fold compared to the galactose oxidase variant M3-5 or by at least 1.01-fold compared to a modified galactose oxidase comprising the mutations of F217A and N268W, or the polypeptide sequence of the modified galactose oxidase has at least 85%, 86%, 87%, 88%, 89%, 90%, 91%, 92%, 93%, 94%, 95%, 96%, 97%, 98%, or 99% sequence identity to SEQ ID NO:68, wherein the enzymatic activity comprises converting a secondary alcohol to a ketone, wherein optionally the secondary alcohol is a bulky secondary alcohol or unactivated secondary alcohol; and (e) reduced enantioselectivity by at least 1.01-fold compared to the galactose oxidase variant M3-5 or by at least 1.01-fold compared to a modified galactose oxidase comprising the mutations of F217A and N268W, or the polypeptide sequence of the modified galactose oxidase has at least 85%, 86%, 87%, 88%, 89%, 90%, 91%, 92%, 93%, 94%, 95%, 96%, 97%, 98%, or 99% sequence identity to SEQ ID NO:68.

14.-25. (canceled)

26. A method of producing a ketone from a secondary alcohol, comprising contacting the secondary alcohol with the modified galactose oxidase of claim 1 under suitable conditions for an oxidation reaction.

27. The method of claim 26, wherein: (i) the secondary alcohol is a bulky secondary alcohol or unactivated secondary alcohol, wherein the bulky secondary alcohol comprises one or more bulky substituents, and wherein the unactivated secondary alcohol is an aliphatic secondary alcohol without a benzene ring in the alpha position adjacent to the alcohol group; or, (ii) the secondary alcohol comprises the formula R.sup.1R.sup.2CHOH, wherein R.sup.1 and R.sup.2 are independently selected from the group consisting of cycloalkyl, aryl, heteroaryl, alkyl, alkylene, alkynyl, haloalkyl, carboxyl, and carbonyl, wherein the cycloalkyl, aryl, heteroaryl, alkyl, alkylene, alkynyl, haloalkyl, carboxyl, and carbonyl is optionally substituted with one or more substituents selected from the group consisting of alkyl, halogen, alkyl halide, alkylene, alkynyl, alkoxy, cyano, oxo, nitro, amino, thiol, carboxyl, ester and hydroxyl; or, (iii) the secondary alcohol is selected from the group consisting of: ##STR00010## ##STR00011## ##STR00012## ##STR00013## ##STR00014## ##STR00015## ##STR00016## or, (iv) the secondary alcohol is chiral or non-chiral, wherein optionally the chiral secondary alcohol is present as (S)-enantiomer, (R)-enantiomer, or a mixture of (S)- and (R)-enantiomers, wherein optionally the chiral secondary alcohol is present as a racemic mixture.

28.-30. (canceled)

31. The method of claim 26, wherein (i) the contacting step is performed at a temperature of 25 C., 30 C., 35 C., 40 C., 45 C., 50 C., 55 C., or more, wherein optionally the temperature is 35 C.; or (ii), the method further comprises, converting the secondary alcohol into an active pharmaceutical ingredient.

32. (canceled)

33. A kit for use in a method of producing a ketone from a secondary alcohol, comprising contactin the secondary alcohol with the modified galactose oxidase of claim 1 under suitable conditions for an oxidation reaction, wherein the kit comprises the modified galactose oxidase of claim 1.

34. The kit of claim 33, wherein the kit further comprises one or more of the following: (a) one or more reaction buffers; (b) one or more reaction vessels, wherein optionally the reaction vessel is a HPLC vial; (c) one or more reaction solvents, wherein optionally the reaction solvent is 5% v/v dimethyl sulfoxide in 100 mM sodium phosphate buffer with a pH of 7; (d) one or more secondary alcohol substrates; (e) one or more co-enzymes to break down the by-product of the oxidation reaction, wherein optionally the co-enzyme is a horseradish peroxidase that breaks down the H.sub.2O.sub.2; and (f) instructions for performing the method of producing a ketone from a secondary alcohol, comprising contacting the secondary alcohol with the modified galactose oxidase of claim 1 under suitable conditions for an oxidation reaction.

Description

BRIEF DESCRIPTION OF DRAWINGS

[0014] The invention will be better understood with reference to the detailed description when considered in conjunction with the non-limiting examples and the accompanying drawings, in which:

[0015] FIG. 1 shows an expanded substrate scope of the identified galactose oxidase variants. Up to 64 substrates were tested were test in the panel.

[0016] FIG. 2 highlights the performance of top performing galactose oxidase variant against five (5) selected examples of bulky benzylic secondary alcohol substrates with reference to the M3-5 variant as benchmark.

[0017] FIG. 3 shows the mutation details on five (5) selected galactose oxidase variants (incorporating three or more synergistic mutations on top of the M3-5 variant) and their high performance liquid chromatography (HPLC) yields of ortho-substituted bulky benzylic secondary alcohol substrates compared to mutant GOh1052 as the benchmark.

[0018] FIG. 4 shows the enzyme profile of 13 top performing galactose oxidase variants in terms of activity (high performance liquid chromatography yield from secondary alcohol substrate 152, 1-phenyl-1-butanol), residual activity (described in FIG. 6), protein expression, and ratio of soluble to insoluble protein compared to GOh1052 variant (F217A, N268W from M3-5) as the benchmark.

[0019] FIG. 5 shows the measured colorimetric activities of 12 selected galactose oxidase variants as well as M3-5 benchmark against the 64 secondary alcohol substrate panel described in FIG. 1. Mutations are given in the top row, variant identifier numbers are given in the second row, and substrate identifier numbers are given in the first column. Colour coded heatmap comparisons have been done horizontally per substrate.

[0020] FIG. 6 shows the procedure for measuring residual activity of a galactose oxidase variant.

DEFINITION OF TERMS

[0021] The following words and terms used herein shall have the meaning indicated:

[0022] As used in this application, the singular form a, an, and the include plural references unless the context clearly dictates otherwise. For example, the term a primer includes a plurality of primers, including mixtures and combinations thereof.

[0023] As used herein, the terms increase and decrease refer to the relative alteration of a chosen trait or characteristic in a subset of a population in comparison to the same trait or characteristic as present in the whole population. An increase thus indicates a change on a positive scale, whereas a decrease indicates a change on a negative scale. The term change, as used herein, also refers to the difference between a chosen trait or characteristic of an isolated population subset in comparison to the same trait or characteristic in the population as a whole. However, this term is without valuation of the difference seen.

[0024] As used herein, the term about in the context of concentration of a substance, size of a substance, length of time, or other stated values means+/5% of the stated value, or +/4% of the stated value, or +/3% of the stated value, or +/2% of the stated value, or +/1% of the stated value, or +/0.5% of the stated value.

[0025] Throughout this disclosure, certain embodiments may be disclosed in a range format. It should be understood that the description in range format is merely for convenience and brevity and should not be construed as an inflexible limitation on the scope of the disclosed ranges. Accordingly, the description of a range should be considered to have specifically disclosed all the possible sub-ranges as well as individual numerical values within that range. For example, description of a range such as from 1 to 6 should be considered to have specifically disclosed sub-ranges such as from 1 to 3, from 1 to 4, from 1 to 5, from 2 to 4, from 2 to 6, from 3 to 6 etc., as well as individual numbers within that range, for example, 1, 2, 3, 4, 5, and 6. This applies regardless of the breadth of the range.

[0026] The disclosure illustratively described herein may suitably be practiced in the absence of any element or elements, limitation or limitations, not specifically disclosed herein. Thus, for example, the terms comprising, including, containing, etc. shall be read expansively and without limitation. Additionally, the terms and expressions employed herein have been used as terms of description and not of limitation, and there is no intention in the use of such terms and expressions of excluding any equivalents of the features shown and described or portions thereof, but it is recognized that various modifications are possible within the scope of the disclosure claimed. Thus, it should be understood that although the present disclosure has been specifically disclosed by preferred embodiments and optional features, modification and variation of the disclosures embodied therein herein disclosed may be resorted to by those skilled in the art, and that such modifications and variations are considered to be within the scope of this disclosure.

[0027] The disclosure has been described broadly and generically herein. Each of the narrower species and subgeneric groupings falling within the generic disclosure also form part of the disclosure. This includes the generic description of the disclosure with a proviso or negative limitation removing any subject matter from the genus, regardless of whether or not the excised material is specifically recited herein.

[0028] Other embodiments are within the following claims and non-limiting examples. In addition, where features or aspects of the disclosure are described in terms of Markush groups, those skilled in the art will recognize that the disclosure is also thereby described in terms of any individual member or subgroup of members of the Markush group.

[0029] As used herein, the terms modified galactose oxidase, galactose oxidase mutant and galactose oxidase variant are used interchangeably, when referring to altered forms of a galactose oxidase resulting from genetic changes or modifications.

[0030] The secondary alcohol may include, but is not limited, a bulky secondary alcohol or an unactivated secondary alcohol. In one example, the bulky secondary alcohol comprises one or more bulky substituents. In one example, an unactivated secondary alcohol is an aliphatic secondary alcohol without a benzene ring in the alpha position adjacent to the alcohol group. The term bulky when used in relation to the secondary alcohol refers to an alcohol that is sterically bulky (or large or complex). In one example, the sterically bulky alcohol is an alkyl alcohol (carbon-based, COH). Examples of sterically bulky alcohols are 1-phenyl-1-butanol, diphenylmethanol, alpha-tetralol, and the like (such as those disclosed herein), as well as derivatives thereof. Similarly, the term bulky when used in relation to substituents refers to a substituent that is sterically bulky (or large or complex). In one example, the bulky secondary alcohol is an alcohol comprising one or more bulky substituents. In one example, the bulky substituent is selected from the group consisting of cycloalkyl, aryl, heteroaryl, alkyl, alkylene, alkynyl, haloalkyl, carboxyl, and carbonyl, wherein the cycloalkyl, aryl, heteroaryl, alkyl, alkylene, alkynyl, haloalkyl, carboxyl, and carbonyl is optionally substituted with one or more substituents selected from the group consisting of alkyl, halogen, alkyl halide, alkylene, alkynyl, alkoxy, cyano, oxo, nitro, amino, thiol, carboxyl, ester and hydroxyl. In one example, the secondary alcohol comprises the formula R.sup.1R.sup.2CHOH, wherein R.sup.1 and R.sup.2 are independently selected from the group consisting of cycloalkyl, aryl, heteroaryl, alkyl, alkylene, alkynyl, haloalkyl, carboxyl, and carbonyl, wherein the cycloalkyl, aryl, heteroaryl, alkyl, alkylene, alkynyl, haloalkyl, carboxyl, and carbonyl is optionally substituted with one or more substituents selected from the group consisting of alkyl, halogen, alkyl halide, alkylene, alkynyl, alkoxy, cyano, oxo, nitro, amino, thiol, carboxyl, ester and hydroxyl.

[0031] The present disclosure includes within its scope all isomeric forms of the compounds disclosed herein, including all diastereomeric isomers, racemates and enantiomers. Thus, formulae (I) and (II) should be understood to include, for example, E, Z, cis, trans, (R), (S), (L), (D), (+), and/or () forms of the compounds, as appropriate in each case.

[0032] The term optionally substituted as used herein means the group to which this term refers may be unsubstituted, or may be substituted with one or more groups independently selected from alkyl, alkenyl, alkynyl, thioalkyl, cycloalkyl, cycloalkenyl, heterocycloalkyl, halo, carboxyl, haloalkyl, haloalkynyl, hydroxyl, alkoxy, thioalkoxy, alkenyloxy, haloalkoxy, haloalkenyloxy, nitro, amino, nitroalkyl, nitroalkenyl, nitroalkynyl, nitroheterocyclyl, alkylamino, dialkylamino, alkenylamine, alkynylamino, acyl, alkenoyl, alkynoyl, acylamino, diacylamino, acyloxy, alkylsulfonyloxy, heterocycloxy, heterocycloamino, haloheterocycloalkyl, alkylsulfenyl, alkylcarbonyloxy, alkylthio, acylthio, phosphorus-containing groups such as phosphono and phosphinyl, aryl, heteroaryl, alkylaryl, alkylheteroaryl, cyano, cyanate, isocyanate, C(O)NH(alkyl), and C(O)N(alkyl).sub.2.

[0033] The term cycloalkyl as used herein refers to cyclic saturated aliphatic groups and includes within its meaning monovalent (cycloalkyl), and divalent (cycloalkylene), saturated, monocyclic, bicyclic, polycyclic or fused polycyclic hydrocarbon radicals having from 3 to 10 carbon atoms, e.g., 3, 4, 5, 6, 7, 8, 9, or 10 carbon atoms. Examples of cycloalkyl groups include but are not limited to cyclopropyl, 2-methylcyclopropyl, cyclobutyl, cyclopentyl, 2-methylcyclopentyl, 3-methylcyclopentyl, cyclohexyl, and the like. In one example, the term fused polycyclic hydrocarbon radical refers to a fused polycyclic hydrocarbon group, ring, or system, wherein the carbon atoms within the fused polycyclic hydrocarbon group, ring or system are covalently bonded.

[0034] The term aromatic group, or variants such as aryl or arylene as used herein refers to monovalent (aryl) and divalent (arylene) single, polynuclear, conjugated and fused residues of aromatic hydrocarbons having from 6 to 10 carbon atoms. Examples of such groups include phenyl, biphenyl, naphthyl, phenanthrenyl, and the like.

[0035] The term heteroaromatic group and variants such as heteroaryl or heteroarylene as used herein, includes within its meaning monovalent (heteroaryl) and divalent (heteroarylene), single, polynuclear, conjugated and fused aromatic radicals having 6 to 20 atoms wherein 1 to 6 atoms are heteroatoms selected from O, N, NH and S. Examples of such groups include pyridyl, 2,2-bipyridyl, phenanthrolinyl, quinolinyl, thiophenyl, and the like. In one example, the term fused aromatic radical refers to a fused aromatic group, ring, or system, wherein the atoms within the fused aromatic group, ring, or system are covalently bonded.

[0036] As used herein, the term alkyl includes within its meaning monovalent (alkyl) and divalent (alkylene) straight chain or branched chain saturated aliphatic groups having from 1 to 10 carbon atoms, e.g., 1, 2, 3, 4, 5, 6, 7, 8, 9, or 10 carbon atoms. For example, the term alkyl includes, but is not limited to, methyl, ethyl, 1-propyl, isopropyl, 1-butyl, 2-butyl, isobutyl, tert-butyl, amyl, 1,2-dimethylpropyl, 1,1-dimethylpropyl, pentyl, isopentyl, hexyl, 4-methylpentyl, 1-methylpentyl, 2-methylpentyl, 3-methylpentyl, 2,2-dimethylbutyl, 3,3-dimethylbutyl, 1,2-dimethylbutyl, 1,3-dimethylbutyl, 1,2,2-trimethylpropyl, 1,1,2-trimethylpropyl, 2-ethylpentyl, 3-ethylpentyl, heptyl, 1-methylhexyl, 2,2-dimethylpentyl, 3,3-dimethylpentyl, 4,4-dimethylpentyl, 1,2-dimethylpentyl, 1,3-dimethylpentyl, 1,4-dimethylpentyl, 1,2,3-trimethylbutyl, 1,1,2-trimethylbutyl, 1,1,3-trimethylbutyl, 5-methylheptyl, 1-methylheptyl, octyl, nonyl, decyl, and the like.

[0037] The term alkenyl includes within its meaning monovalent (alkenyl) and divalent (alkenylene) straight or branched chain unsaturated aliphatic hydrocarbon groups having from 2 to 10 carbon atoms, e.g., 2, 3, 4, 5, 6, 7, 8, 9, or 10 carbon atoms and having at least one double bond, of either E, Z, cis or trans stereochemistry where applicable, anywhere in the alkyl chain. Examples of alkenyl groups include but are not limited to ethenyl, vinyl, allyl, 1-methylvinyl, 1-propenyl, 2-propenyl, 2-methyl-1-propenyl, 2-methyl-1-propenyl, 1-butenyl, 2-butenyl, 3-butentyl, 1,3-butadienyl, 1-pentenyl, 2-pententyl, 3-pentenyl, 4-pentenyl, 1,3-pentadienyl, 2,4-pentadienyl, 1,4-pentadienyl, 3-methyl-2-butenyl, 1-hexenyl, 2-hexenyl, 3-hexenyl, 1,3-hexadienyl, 1,4-hexadienyl, 2-methylpentenyl, 1-heptenyl, 2-heptentyl, 3-heptenyl, 1-octenyl, 1-nonenyl, 1-decenyl, and the like.

[0038] The term alkynyl as used herein includes within its meaning monovalent (alkynyl) and divalent (alkynylene) straight or branched chain unsaturated aliphatic hydrocarbon groups having from 2 to 10 carbon atoms and having at least one triple bond anywhere in the carbon chain. Examples of alkynyl groups include but are not limited to ethynyl, 1-propynyl, 1-butynyl, 2-butynyl, 1-methyl-2-butynyl, 3-methyl-1-butynyl, 1-pentynyl, 1-hexynyl, methylpentynyl, 1-heptynyl, 2-heptynyl, 1-octynyl, 2-octynyl, 1-nonyl, 1-decynyl, and the like.

[0039] The term haloalkyl refers to a straight-or branched-chain alkenyl group having from 2-12 carbon atoms in the chain and where one or more hydrogens is substituted with a halogen. Illustrative haloalkyl groups include trifluoromethyl, 2-bromopropyl, 3-chlorohexyl, 1-iodo-isobutyl, and the like.

[0040] The term carboxyl as used herein is intended to mean the radical-C(O) OH.

[0041] The term carbonyl as used herein refers to a functional group comprising a carbon atom with a double bond to an oxygen atom, which can be written as C(O) or as C(O).

[0042] The term halogen or variants such as halide or halo as used herein refers to fluorine, chlorine, bromine and iodine.

[0043] The term alkyl halide as used herein includes within its meaning straight or branched chain alkyl groups having from 2-12 carbon atoms and in which one or more of its hydrogen atoms are substituted with the corresponding number of halogen atoms. An alkyl halide with C.sub.n carbon atoms may have at least one up to 2.sub.n+1 halogen atoms, and the halogen atoms may be the same or different. Examples of alkyl halide groups include but are not limited to CF.sub.3, C.sub.2F.sub.5, CHF.sub.2, CHCl.sub.2, CHBr.sub.2, C.sub.2Cl.sub.5 and the like.

[0044] The term alkoxy as used herein refers to straight chain or branched alkyloxy groups. Examples include methoxy, ethoxy, n-propoxy, isopropoxy, tert-butoxy, and the like.

[0045] The term cyano, used interchangeably with nitrile, refers to a group comprising a carbon atom with a triple bond to a nitrogen atom, which can be written as CN or CN.

[0046] The term oxo as used herein is intended to mean the radical O.

[0047] The term amino as used herein refers to groups of the form NR.sub.aR.sub.b wherein R.sub.a and R.sub.b are individually selected from the group including but not limited to hydrogen, optionally substituted alkyl, optionally substituted alkenyl, optionally substituted alkynyl, and optionally substituted aryl groups.

[0048] The term nitro as used herein refers to a functional group comprising a nitrogen atom joined to two oxygen atoms, which can be written as ONO or NO.sub.2.

[0049] The term thiol as used herein refers to a group comprising the formula SH.

[0050] The term ester as used herein refers to a group represented by the general formula R.sub.cCOOR.sub.d. R.sub.c and/or R.sub.d may include, but is not limited to alkyl, aryl, haloalkyl.

[0051] The term hydroxyl as used herein refers to the group OH.

[0052] In the phrase even numbered sequences, the term even number refers to any number that is a multiple of 2. In one example, even numbered sequences of SEQ ID NOS: 1-298 refer to SEQ ID NOS: 2, 4, 6, 8, 10, 12, 14, 16, 18, 20, 22, and so on until SEQ ID NO: 298. In another example, even numbered sequences of SEQ ID NOS: 77-298 refer to SEQ ID NOS: 78, 80, 82, 84, 86, 88, 90, 92, 94, 96, 98, 100, 102, and so on until SEQ ID NO: 298.

[0053] In the phrase odd numbered sequences, the term odd number refers to any number that is not a multiple of 2. In one example, odd numbered sequences of SEQ ID NOS: 1-298 refer to SEQ ID NOS: 1, 3, 5, 7, 9, 11, 13, 15, 17, 19, 21, and so on until SEQ ID NO: 297. In another example, odd numbered sequences of SEQ ID NOS: 77-298 refer to SEQ ID NOS: 77, 79, 81, 83, 85, 87, 89, 91, 93, 95, 97, 99, 101 and so on until SEQ ID NO: 297.

DETAILED DESCRIPTION

[0054] The present disclosure is directed to a panel of modified galactose oxidase enzymes based on copper-dependent galactose oxidase from Fusarium graminearum. The present disclosure discloses 118 unique mutations (either singly or in combination) from the backbone M3-5 variant that convey improved enhancement in activity and/or stability, and/or solubility, and/or protein expression, and/or selectivity compared to M3-5 variant. The present disclosure describes galactose oxidase variants with enhanced protein expression, solubility, thermal stability and enzymatic activity, and reduced enantioselectivity, compared to galactose oxidase variants known in the art, and methods of producing the same. Galactose oxidases catalyse the oxidation of secondary alcohol substrates to ketones in accordance with the chemical equation shown below:

##STR00001##

[0055] The inventors therefore screened and identified galactose oxidase variants that are capable of accepting a wide range of bulky secondary alcohols (e.g., biphenyl, C.sub.8 alkyl sidechain, ortho-substitution) with good tolerance of halogen (e.g., Cl, Br), alkene, alkyne, and nitro functional groups. The galactose oxidase variants disclosed herein are also capable of accepting unactivated secondary alcohols as substrates.

[0056] In one aspect, the present disclosure refers to a modified galactose oxidase comprising a polypeptide sequence having at least 85%, 86%, 87%, 88%, 89%, 90%, 91%, 92%, 93%, 94%, 95%, 96%, 97%, 98%, or 99% sequence identity to SEQ ID NO: 6, wherein SEQ ID NO: 6 is a polypeptide sequence of galactose oxidase variant M3-5, wherein the galactose oxidase variant M3-5 comprises mutations of S33P, M93V, G218E, W313F, R353M, Q429T, V517A, and N558D relative to the wildtype galactose oxidase from Fusarium graminearum (SEQ ID NO: 4), and wherein the polypeptide sequence of the modified galactose oxidase further comprises at least one mutation at one or more positions selected from the group consisting of 24, 26, 28, 45, 49, 65, 69, 104, 114, 117, 153, 157, 172, 173, 175, 193, 194, 195, 197, 198, 202, 214, 217, 218, 220, 224, 226, 239, 240, 250, 259, 265, 268, 269, 284, 294, 313, 314, 325, 341, 346, 348, 352, 353, 356, 389, 401, 429, 447, 485, 487, 537, 538, 546, 559, 576, 599, and 662, wherein the position of the mutation is numbered with reference to SEQ ID NO: 6.

[0057] In one example, the present disclosure refers to the modified galactose oxidase disclosed herein, wherein the mutation is selected from the group consisting of A24H, A24N, A26H, A26R, I28F, I28M, I28R, Q45D, Q45E, Q45N, E49K, F65P, N69D, N69E, N69F, N69H, N69L, N69M, N69T, N69W, N69Y, W104G, W104N, S114N, S114R, T117D, T153K, T153R, G157N, S172E, S173K, S173R, T175E, T175H, T175I, T175K, V193T, P194C, A195S, A195T, A195V, A197C, A197G, A198I, T202D, T202I, T202K, T202Q, N214R, N214S, F217A, F217C, F217D, F217E, F217G, F217H, F217I, F217K, F217L, F217M, F217N, F217P, F217Q, F217R, F217S, F217T, F217V, F217Y, E218F, E218K, E218P, E218Y, S220T, I224W, L226Q, L226V, D239E, D239P, D239Q, R240G, F250E, F250Y, N259T, T265S, N268W, D269N, I284S, I284Y, G294A, F313R, S314C, Y325F, N341W, A346L, K348S, Y352T, Y352W, M353F, N356K, N356R, N356W, K389I, A401D, T429W, T447A, I485A, I485K, I485R, F487R, L537G, C538K, C538R, F546M, S559P, S576D, Y599M, Q662D, and Q662P.

[0058] In one specific example, the present disclosure refers to the modified galactose oxidase disclosed herein, wherein the mutation is selected from the group consisting of I28R, A24H, A195S, A195T, A195V, A198I, T202I, F217A, E218F, E218K, L226Q, D239E, N259T, N268W, S314C, Y352W, Y599M, and combinations thereof.

[0059] In one example, the present disclosure refers to the modified galactose oxidase disclosed herein, wherein the mutation is selected from the group consisting of: [0060] M353F; [0061] S314C; [0062] L537G; [0063] F217V; [0064] F217P; [0065] F217Q; [0066] F217N; [0067] F217S; [0068] N268W; [0069] E218P; [0070] F217I; [0071] F217T; [0072] F217L; [0073] F217E; [0074] F217Y; [0075] F217A; [0076] F217C; [0077] F217D; [0078] F217G; [0079] F217H; [0080] F217K; [0081] F217M; [0082] F217R; [0083] a combination of F217P and E218P; [0084] a combination of F217P and L537G; [0085] a combination of F217P, E218P and L537G; [0086] a combination of F217V and E218P; [0087] a combination of F217V and L537G; [0088] a combination of F217V, E218P and L537G; [0089] a combination of E218P and L537G; [0090] a combination of F217A and N268W; [0091] a combination of F217A, N268W and M353F; [0092] a combination of F217A, N268W and S314C; [0093] a combination of F217G and N268W; [0094] a combination of F217G, N268W and M353F; [0095] a combination of F217A, N268W and A195S; [0096] a combination of F217A, N268W and V193T; [0097] a combination of F217A, N268W and N259T; [0098] a combination of F217A, N268W and Y325F; [0099] a combination of F217A, N268W and G294A; [0100] a combination of F217A, N268W and A195T; [0101] a combination of F217A, N268W and Y352T; [0102] a combination of F217A, N268W and N341W; [0103] a combination of F217A, N268W and A197C; [0104] a combination of F217A, N268W and R240G; [0105] a combination of F217A, N268W and A198I; [0106] a combination of F217A, N268W and K348S; [0107] a combination of F217A, N268W and T202D; [0108] a combination of F217A, N268W and T202Q; [0109] a combination of F217A, N268W and T202I; [0110] a combination of F217A, N268W and T202K; [0111] a combination of F217A, N268W and P194C; [0112] a combination of F217A, N268W and A346L; [0113] a combination of F217A, N268W and K389I; [0114] a combination of F217A, N268W and Y352W; [0115] a combination of F217A, N268W and C538K; [0116] a combination of F217A, N268W and C538R; [0117] a combination of F217A, N268W and F250E; [0118] a combination of F217A, N268W and F250Y; [0119] a combination of F217A, N268W and N356K; [0120] a combination of F217A, N268W and N356R; [0121] a combination of F217A, N268W and N356W; [0122] a combination of F217A, N268W and F487R; [0123] a combination of F217A, N268W and T429W; [0124] a combination of F217A, N268W and E218K; [0125] a combination of F217A, N268W and F313R; [0126] a combination of F217A, N268W and I284Y; [0127] a combination of F217A, N268W and A24H; [0128] a combination of F217A, N268W and I28R; [0129] a combination of F217A, N268W and I28M; [0130] a combination of F217A, N268W and S576D; [0131] a combination of F217A, N268W and I284S; [0132] a combination of F217A, N268W and F65P; [0133] a combination of F217A, N268W and T153R; [0134] a combination of F217A, N268W and A197G; [0135] a combination of F217A, N268W and T265S; [0136] a combination of F217A, N268W and S220T; [0137] a combination of F217A, N268W and N214S; [0138] a combination of F217A, N268W and I485A; [0139] a combination of F217A, N268W and N214R; [0140] a combination of F217A, N268W and D269N; [0141] a combination of F217A, N268W and I485R; [0142] a combination of F217A, N268W and I485K; [0143] a combination of F217A, N268W and D239E; [0144] a combination of F217A, N268W and Ti17D; [0145] a combination of F217A, N268W and S114R; [0146] a combination of F217A, N268W and S559P; [0147] a combination of F217A, N268W and S114N; [0148] a combination of F217A, N268W and Q662P; [0149] a combination of F217A, N268W and S173R; [0150] a combination of F217A, N268W and D239P; [0151] a combination of F217A, N268W and S172E; [0152] a combination of F217A, N268W and Q662D; [0153] a combination of F217A, N268W and S173K; [0154] a combination of F217A, N268W and A195V; [0155] a combination of F217A, N268W and E218F; [0156] a combination of F217A, N268W and L226Q; [0157] a combination of F217A, N268W and I224W; [0158] a combination of F217A, N268W and A26R; [0159] a combination of F217A, N268W and I28F; [0160] a combination of F217A, N268W and E218Y; [0161] a combination of F217A, N268W and L226V; [0162] a combination of F217A, N268W and D239Q; [0163] a combination of F217A, N268W and F546M; [0164] a combination of F217A, N268W and A24N; [0165] a combination of F217A, N268W and A26H; [0166] a combination of F217A, N268W and Y599M; [0167] a combination of F217A, N268W and G157N; [0168] a combination of F217A, N268W and Q45D; [0169] a combination of F217A, N268W and Q45E; [0170] a combination of F217A, N268W and Q45N; [0171] a combination of F217A, N268W and E49K; [0172] a combination of F217A, N268W and N69D; [0173] a combination of F217A, N268W and N69E; [0174] a combination of F217A, N268W and N69F; [0175] a combination of F217A, N268W and N69H; [0176] a combination of F217A, N268W and N69L; [0177] a combination of F217A, N268W and N69M; [0178] a combination of F217A, N268W and N69T; [0179] a combination of F217A, N268W and N69W; [0180] a combination of F217A, N268W and N69Y; [0181] a combination of F217A, N268W and W104G; [0182] a combination of F217A, N268W and W104N; [0183] a combination of F217A, N268W and T175E; [0184] a combination of F217A, N268W and T175H; [0185] a combination of F217A, N268W and T175I; [0186] a combination of F217A, N268W and T175K; [0187] a combination of F217A, N268W and A401D; [0188] a combination of F217A, N268W, A195T and Y352W; [0189] a combination of F217A, N268W, N341W and Y352T; [0190] a combination of F217A, N268W, A198I and N259T; [0191] a combination of F217A, N268W, A195S and N341W; [0192] a combination of F217A, N268W, T153K and A195S; [0193] a combination of F217A, N268W, I28R and K389I; [0194] a combination of F217A, N268W, T153R and A195T; [0195] a combination of F217A, N268W, I28R, T153R, A198I and N341W; [0196] a combination of F217A, N268W, A195T, N259T and N341W; [0197] a combination of F217A, N268W, I28R, A195T, N259T and K389I; [0198] a combination of F217A, N268W, I28R, N259T and N341W; [0199] a combination of F217A, N268W, I28R, A195S and K389I; [0200] a combination of F217A, N268W, A195T and N341W; [0201] a combination of F217A, N268W, I28R, A195T, N341W and K389I; [0202] a combination of F217A, N268W, I28R, A195T, N259T and T447A; [0203] a combination of F217A, N268W, I28R, A195S, N259T and N341W; [0204] a combination of F217A, N268W, I28R, A195T, N259T, N341W and K389I; and [0205] a combination of F217A, N268W, T153R and N341W.

[0206] In one example, there is provided a galactose oxidase variant GOh1006, which has a M353F mutation in addition to those in the M3-5 variant. In one example, there is provided a galactose oxidase variant GOh1008, which has a S314C mutation in addition to those in the M3-5 variant. In one example, there is provided a galactose oxidase variant GOh1013, which has a L537G mutation in addition to those in the M3-5 variant. In one example, there is provided a galactose oxidase variant GOh1015, which has a F217V mutation in addition to those in the M3-5 variant. In one example, there is provided a galactose oxidase variant GOh1016, which has a F217P mutation in addition to those in the M3-5 variant. In one example, there is provided a galactose oxidase variant GOh1017, which has a F217Q mutation in addition to those in the M3-5 variant. In one example, there is provided a galactose oxidase variant GOh1018, which has a F217N mutation in addition to those in the M3-5 variant. In one example, there is provided a galactose oxidase variant GOh1020, which has a F217S mutation in addition to those in the M3-5 variant. In one example, there is provided a galactose oxidase variant GOh1021, which has a N268W mutation in addition to those in the M3-5 variant. In one example, there is provided a galactose oxidase variant GOh1025, which has a E218P mutation in addition to those in the M3-5 variant. In one example, there is provided a galactose oxidase variant GOhM030, which has a F217I mutation in addition to those in the M3-5 variant. In one example, there is provided a galactose oxidase variant GOh1031, which has a F217T mutation in addition to those in the M3-5 variant. In one example, there is provided a galactose oxidase variant GOh1032, which has a F217L mutation in addition to those in the M3-5 variant. In one example, there is provided a galactose oxidase variant GOh1034, which has a F217E mutation in addition to those in the M3-5 variant. In one example, there is provided a galactose oxidase variant GOh1035, which has a F217Y mutation in addition to those in the M3-5 variant. In one example, there is provided a galactose oxidase variant GOh1036, which has a F217A mutation in addition to those in the M3-5 variant. In one example, there is provided a galactose oxidase variant GOh1037, which has a F217C mutation in addition to those in the M3-5 variant. In one example, there is provided a galactose oxidase variant GOh1038, which has a F217D mutation in addition to those in the M3-5 variant. In one example, there is provided a galactose oxidase variant GOh1039, which has a F217G mutation in addition to those in the M3-5 variant. In one example, there is provided a galactose oxidase variant GOh1040, which has a F217H mutation in addition to those in the M3-5 variant. In one example, there is provided a galactose oxidase variant GOh1041, which has a F217K mutation in addition to those in the M3-5 variant. In one example, there is provided a galactose oxidase variant GOh1042, which has a F217M mutation in addition to those in the M3-5 variant. In one example, there is provided a galactose oxidase variant GOh1043, which has a F217R mutation in addition to those in the M3-5 variant. In one example, there is provided a galactose oxidase variant GOh1045, which has F217P and E218P mutations in addition to those in the M3-5 variant. In one example, a modified galactose oxidase having the F217P and E218P mutations corresponds to galactose oxidase variant GOh1045. In one example, there is provided a galactose oxidase variant GOh1046, which has FF217P and L537G mutations in addition to those in the M3-5 variant. In one example, there is provided a galactose oxidase variant GOh1047, which has F217P, E218P, and L537G mutations in addition to those in the M3-5 variant. In one example, there is provided a galactose oxidase variant GOh1048, which has F217V and E218P mutations in addition to those in the M3-5 variant. In one example, there is provided a galactose oxidase variant GOh1049, which has F217V and L537G mutations in addition to those in the M3-5 variant. In one example, there is provided a galactose oxidase variant GOh1050, which has F217V, E218P, and L537G mutations in addition to those in the M3-5 variant. In one example, there is provided a galactose oxidase variant GOh1051, which has E218P and L537G mutations in addition to those in the M3-5 variant. In one example, there is provided a galactose oxidase variant GOh1052, which has F217A and N268W mutations in addition to those in the M3-5 variant. In one example, there is provided a galactose oxidase variant GOh1053, which has F217A, N268W, and M353F mutations in addition to those in the M3-5 variant. In one example, there is provided a galactose oxidase variant GOh1054, which has F217A, N268W, and S314C mutations in addition to those in the M3-5 variant. In one example, there is provided a galactose oxidase variant GOh1055, which has F217G and N268W mutations in addition to those in the M3-5 variant. In one example, there is provided a galactose oxidase variant GOh1056, which has F217G, N268W, and M353 mutations in addition to those in the M3-5 variant. In one example, there is provided a galactose oxidase variant GOh2001, which has F217A, N268W, and A195S mutations in addition to those in the M3-5 variant. In one example, there is provided a galactose oxidase variant GOh2002, which has F217A, N268W, and V193T mutations in addition to those in the M3-5 variant. In one example, there is provided a galactose oxidase variant GOh2008, which has F217A, N268W, and N259T mutations in addition to those in the M3-5 variant. In one example, there is provided a galactose oxidase variant GOh2010, which has F217A, N268W, and Y325F mutations in addition to those in the M3-5 variant. In one example, there is provided a galactose oxidase variant GOh2011, which has F217A, N268W, and G294A mutations in addition to those in the M3-5 variant. In one example, there is provided a galactose oxidase variant GOh2012, which has F217A, N268W, and A195T mutations in addition to those in the M3-5 variant. In one example, there is provided a galactose oxidase variant GOh2013, which has F217A, N268W, and Y352T mutations in addition to those in the M3-5 variant. In one example, there is provided a galactose oxidase variant GOh2014, which has F217A, N268W, and N341W mutations in addition to those in the M3-5 variant. In one example, there is provided a galactose oxidase variant GOh2015, which has F217A, N268W, and A197C mutations in addition to those in the M3-5 variant. In one example, there is provided a galactose oxidase variant GOh2016, which has F217A, N268W, and R240G mutations in addition to those in the M3-5 variant. In one example, there is provided a galactose oxidase variant GOh2017, which has F217A, N268W, and A198I mutations in addition to those in the M3-5 variant. In one example, there is provided a galactose oxidase variant GOh2018, which has F217A, N268W, and K348S mutations in addition to those in the M3-5 variant. In one example, there is provided a galactose oxidase variant GOh2019, which has F217A, N268W, and T202D mutations in addition to those in the M3-5 variant. In one example, there is provided a galactose oxidase variant GOh2020, which has F217A, N268W, and T202Q mutations in addition to those in the M3-5 variant. In one example, there is provided a galactose oxidase variant GOh2021, which has F217A, N268W, and T202I mutations in addition to those in the M3-5 variant. In one example, there is provided a galactose oxidase variant GOh2022, which has F217A, N268W, and T202K mutations in addition to those in the M3-5 variant. In one example, there is provided a galactose oxidase variant GOh2023, which has F217A, N268W, and P194C mutations in addition to those in the M3-5 variant. In one example, there is provided a galactose oxidase variant GOh2025, which has F217A, N268W, and A346L mutations in addition to those in the M3-5 variant. In one example, there is provided a galactose oxidase variant GOh2026, which has F217A, N268W, and K389I mutations in addition to those in the M3-5 variant. In one example, there is provided a galactose oxidase variant GOh2027, which has F217A, N268W, and Y352W mutations in addition to those in the M3-5 variant. In one example, there is provided a galactose oxidase variant GOh2028, which has F217A, N268W, and C538K mutations in addition to those in the M3-5 variant. In one example, there is provided a galactose oxidase variant GOh2029, which has F217A, N268W, and C538R mutations in addition to those in the M3-5 variant. In one example, there is provided a galactose oxidase variant GOh2030, which has F217A, N268W, and F250E mutations in addition to those in the M3-5 variant. In one example, there is provided a galactose oxidase variant GOh2031, which has F217A, N268W, and F250Y mutations in addition to those in the M3-5 variant. In one example, there is provided a galactose oxidase variant GOh2032, which has F217A, N268W, and N356K mutations in addition to those in the M3-5 variant. In one example, there is provided a galactose oxidase variant GOh2033, which has F217A, N268W, and N356R mutations in addition to those in the M3-5 variant. In one example, there is provided a galactose oxidase variant GOh2034, which has F217A, N268W, and N356W mutations in addition to those in the M3-5 variant. In one example, there is provided a galactose oxidase variant GOh2037, which has F217A, N268W, and F487R mutations in addition to those in the M3-5 variant. In one example, there is provided a galactose oxidase variant GOh2038, which has F217A, N268W, and T429W mutations in addition to those in the M3-5 variant. In one example, there is provided a galactose oxidase variant GOh2039, which has F217A, N268W, and E218K mutations in addition to those in the M3-5 variant. In one example, there is provided a galactose oxidase variant GOh2041, which has F217A, N268W, and F313R mutations in addition to those in the M3-5 variant. In one example, there is provided a galactose oxidase variant GOh2043, which has F217A, N268W, and I284Y mutations in addition to those in the M3-5 variant. In one example, there is provided a galactose oxidase variant GOh2044, which has F217A, N268W, and A24H mutations in addition to those in the M3-5 variant. In one example, there is provided a galactose oxidase variant GOh2045, which has F217A, N268W, and I28R mutations in addition to those in the M3-5 variant. In one example, there is provided a galactose oxidase variant GOh2046, which has F217A, N268W, and I28M mutations in addition to those in the M3-5 variant. In one example, there is provided a galactose oxidase variant GOh2047, which has F217A, N268W, and S576D mutations in addition to those in the M3-5 variant. In one example, there is provided a galactose oxidase variant GOh2048, which has F217A, N268W, and I284S mutations in addition to those in the M3-5 variant. In one example, there is provided a galactose oxidase variant GOh2050, which has F217A, N268W, and F65P mutations in addition to those in the M3-5 variant. In one example, there is provided a galactose oxidase variant GOh2053, which has F217A, N268W, and T153R mutations in addition to those in the M3-5 variant. In one example, there is provided a galactose oxidase variant GOh2055, which has F217A, N268W, and A197G mutations in addition to those in the M3-5 variant. In one example, there is provided a galactose oxidase variant GOh2056, which has F217A, N268W, and T265S mutations in addition to those in the M3-5 variant. In one example, there is provided a galactose oxidase variant GOh2057, which has F217A, N268W, and S220T mutations in addition to those in the M3-5 variant. In one example, there is provided a galactose oxidase variant GOh2058, which has F217A, N268W, and N214S mutations in addition to those in the M3-5 variant. In one example, there is provided a galactose oxidase variant GOh2061, which has F217A, N268W, and I485A mutations in addition to those in the M3-5 variant. In one example, there is provided a galactose oxidase variant GOh2064, which has F217A, N268W, and N214R mutations in addition to those in the M3-5 variant. I In one example, there is provided a galactose oxidase variant GOh2066, which has F217A, N268W, and D269N mutations in addition to those in the M3-5 variant. In one example, there is provided a galactose oxidase variant GOh2067, which has F217A, N268W, and I485R mutations in addition to those in the M3-5 variant. In one example, there is provided a galactose oxidase variant GOh2068, which has F217A, N268W, and I485K mutations in addition to those in the M3-5 variant. In one example, there is provided a galactose oxidase variant GOh2070, which has F217A, N268W, and D239E mutations in addition to those in the M3-5 variant. In one example, there is provided a galactose oxidase variant GOh2071, which has F217A, N268W, and T117D mutations in addition to those in the M3-5 variant. In one example, there is provided a galactose oxidase variant GOh2072, which has F217A, N268W, and S114R mutations in addition to those in the M3-5 variant. In one example, there is provided a galactose oxidase variant GOh2073, which has F217A, N268W, and S559P mutations in addition to those in the M3-5 variant. In one example, there is provided a galactose oxidase variant GOh2074, which has F217A, N268W, and S114N mutations in addition to those in the M3-5 variant. In one example, there is provided a galactose oxidase variant GOh2075, which has F217A, N268W, and Q662P mutations in addition to those in the M3-5 variant. In one example, there is provided a galactose oxidase variant GOh2076, which has F217A, N268W, and S173R mutations in addition to those in the M3-5 variant. In one example, there is provided a galactose oxidase variant GOh2077, which has F217A, N268W, and D239P mutations in addition to those in the M3-5 variant. In one example, there is provided a galactose oxidase variant GOh2078, which has F217A, N268W, and S172E mutations in addition to those in the M3-5 variant. In one example, there is provided a galactose oxidase variant GOh2079, which has F217A, N268W, and Q662D mutations in addition to those in the M3-5 variant. In one example, there is provided a galactose oxidase variant GOh2080, which has F217A, N268W, and S173K mutations in addition to those in the M3-5 variant. In one example, there is provided a galactose oxidase variant GOh2081, which has F217A, N268W, and A195V mutations in addition to those in the M3-5 variant. In one example, there is provided a galactose oxidase variant GOh2082, which has F217A, N268W, and E218F mutations in addition to those in the M3-5 variant. In one example, there is provided a galactose oxidase variant GOh2083, which has F217A, N268W, and L226Q mutations in addition to those in the M3-5 variant. In one example, there is provided a galactose oxidase variant GOh2084, which has F217A, N268W, and I224W mutations in addition to those in the M3-5 variant. In one example, there is provided a galactose oxidase variant GOh2085, which has F217A, N268W, and I28F mutations in addition to those in the M3-5 variant. In one example, there is provided a galactose oxidase variant GOh2086, which has F217A, N268W, and I28F mutations in addition to those in the M3-5 variant. In one example, there is provided a galactose oxidase variant GOh2087, which has F217A, N268W, and E218Y mutations in addition to those in the M3-5 variant. In one example, there is provided a galactose oxidase variant GOh2088, which has F217A, N268W, and L226V mutations in addition to those in the M3-5 variant. In one example, there is provided a galactose oxidase variant GOh2089, which has F217A, N268W, and D239Q mutations in addition to those in the M3-5 variant. In one example, there is provided a galactose oxidase variant GOh2090, which has F217A, N268W, and F546M mutations in addition to those in the M3-5 variant. In one example, there is provided a galactose oxidase variant GOh2091, which has F217A, N268W, and A24N mutations in addition to those in the M3-5 variant. In one example, there is provided a galactose oxidase variant GOh2092, which has F217A, N268W, and A26H mutations in addition to those in the M3-5 variant. In one example, there is provided a galactose oxidase variant GOh2093, which has F217A, N268W, and Y599M mutations in addition to those in the M3-5 variant. In one example, there is provided a galactose oxidase variant GOh2094, which has F217A, N268W, and G157N mutations in addition to those in the M3-5 variant. In one example, there is provided a galactose oxidase variant GOh2097, which has F217A, N268W, and Q45D mutations in addition to those in the M3-5 variant. In one example, there is provided a galactose oxidase variant GOh2098, which has F217A, N268W, and Q45E mutations in addition to those in the M3-5 variant. In one example, there is provided a galactose oxidase variant GOh2099, which has F217A, N268W, and Q45N mutations in addition to those in the M3-5 variant. In one example, there is provided a galactose oxidase variant GOh2100, which has F217A, N268W, and E49K mutations in addition to those in the M3-5 variant. In one example, there is provided a galactose oxidase variant GOh2101, which has F217A, N268W, and N69D mutations in addition to those in the M3-5 variant. In one example, there is provided a galactose oxidase variant GOh2102, which has F217A, N268W, and N69E mutations in addition to those in the M3-5 variant. In one example, there is provided a galactose oxidase variant GOh2103, which has F217A, N268W, and N69F mutations in addition to those in the M3-5 variant. In one example, there is provided a galactose oxidase variant GOh2104, which has F217A, N268W, and N69H mutations in addition to those in the M3-5 variant. In one example, there is provided a galactose oxidase variant GOh2105, which has F217A, N268W, and N69L mutations in addition to those in the M3-5 variant. In one example, there is provided a galactose oxidase variant GOh2106, which has F217A, N268W, and N69M mutations in addition to those in the M3-5 variant. In one example, there is provided a galactose oxidase variant GOh2107, which has F217A, N268W, and N69T mutations in addition to those in the M3-5 variant. In one example, there is provided a galactose oxidase variant GOh2108, which has F217A, N268W, and N69W mutations in addition to those in the M3-5 variant. In one example, there is provided a galactose oxidase variant GOh2109, which has F217A, N268W, and N69Y mutations in addition to those in the M3-5 variant. In one example, there is provided a galactose oxidase variant GOh2110, which has F217A, N268W, and W104G mutations in addition to those in the M3-5 variant. In one example, there is provided a galactose oxidase variant GOh2111, which has F217A, N268W, and W104N mutations in addition to those in the M3-5 variant. In one example, there is provided a galactose oxidase variant GOh2l14, which has F217A, N268W, and T175E mutations in addition to those in the M3-5 variant. In one example, there is provided a galactose oxidase variant GOh2115, which has F217A, N268W, and T175H mutations in addition to those in the M3-5 variant. In one example, there is provided a galactose oxidase variant GOh2116, which has F217A, N268W, and T175I mutations in addition to those in the M3-5 variant. In one example, there is provided a galactose oxidase variant GOh2117, which has F217A, N268W, and T175K mutations in addition to those in the M3-5 variant. In one example, there is provided a galactose oxidase variant GOh2l19, which has F217A, N268W, and A401D mutations in addition to those in the M3-5 variant. In one example, there is provided a galactose oxidase variant GOh3001, which has F217A, N268W, A195T, and Y352W mutations in addition to those in the M3-5 variant. In one example, there is provided a galactose oxidase variant GOh3002, which has F217A, N268W, N341W, and Y352T mutations in addition to those in the M3-5 variant. In one example, there is provided a galactose oxidase variant GOh3003, which has F217A, N268W, A198I, and N259T mutations in addition to those in the M3-5 variant. In one example, there is provided a galactose oxidase variant GOh3004, which has F217A, N268W, A195S, and N341W mutations in addition to those in the M3-5 variant. In one example, there is provided a galactose oxidase variant GOh3005, which has F217A, N268W, T153K, and A195S mutations in addition to those in the M3-5 variant. In one example, there is provided a galactose oxidase variant GOh3006, which has F217A, N268W, I28R, and K389I mutations in addition to those in the M3-5 variant. In one example, there is provided a galactose oxidase variant GOh3007, which has F217A, N268W, T153R, and A195T mutations in addition to those in the M3-5 variant. In one example, there is provided a galactose oxidase variant GOh3008, which has F217A, N268W, I28R, T153R, A198I, and N341W mutations in addition to those in the M3-5 variant. In one example, there is provided a galactose oxidase variant GOh3009, which has F217A, N268W, A195T, N259T, and N341W mutations in addition to those in the M3-5 variant. In one example, there is provided a galactose oxidase variant GOh3013, which has F217A, N268W, I28R, A195T, N259T, and K389I mutations in addition to those in the M3-5 variant. In one example, there is provided a galactose oxidase variant GOh3015, which has F217A, N268W, I28R, N259T, and N341W mutations in addition to those in the M3-5 variant. In one example, there is provided a galactose oxidase variant GOh3018, which has F217A, N268W, I28R, A195S, and K389I mutations in addition to those in the M3-5 variant. In one example, there is provided a galactose oxidase variant GOh3019, which has F217A, N268W, A195T, and N341W mutations in addition to those in the M3-5 variant. In one example, there is provided a galactose oxidase variant GOh3023, which has F217A, N268W, I28R, A195T, N341W mutations in addition to those in the M3-5 variant. In one example, there is provided a galactose oxidase variant GOh3026, which has F217A, N268W, I28R, A195T, N259T, and T447A mutations in addition to those in the M3-5 variant. In one example, there is provided a galactose oxidase variant GOh3032, which has F217A, N268W, I28R, A195S, N259T, and N341W mutations in addition to those in the M3-5 variant. In one example, there is provided a galactose oxidase variant GOh3038, which has F217A, N268W, I28R, A195T, N259T, N341W, and K389I mutations in addition to those in the M3-5 variant. In one example, there is provided a galactose oxidase variant GOh3049, which has F217A, N268W, T153R, and N341W mutations in addition to those in the M3-5 variant. In one example, a modified galactose oxidase having the F217A, N268W, T153R, and N341W mutations corresponds to galactose oxidase variant GOh3049.

[0207] In one example, the present disclosure refers to the modified galactose oxidase disclosed herein, wherein the polypeptide sequence of the modified galactose oxidase has at least 85%, 86%, 87%, 88%, 89%, 90%, 91%, 92%, 93%, 94%, 95%, 96%, 97%, 98%, or 99% sequence identity to the sequence of at least one modified galactose oxidase variant set forth in the even numbered sequences of SEQ ID NOS: 7-298. In one example, the present disclosure refers to the modified galactose oxidase disclosed herein, wherein the polypeptide sequence of the modified galactose oxidase has at least 85%, 86%, 87%, 88%, 89%, 90%, 91%, 92%, 93%, 94%, 95%, 96%, 97%, 98%, or 99% sequence identity to the sequence of at least one modified galactose oxidase variant set forth in the following even numbered sequences: SEQ ID NOS: 8, 10, 12, 14, 16, 18, 20, 22, 24, 26, 28, 30, 32, 34, 36, 38, 40, 42, 44, 46, 48, 50, 52, 54, 56, 58, 60, 62, 64, 66, 68, 70, 72, 74, 76, 78, 80, 82, 84, 86, 88, 90, 92, 94, 96, 98, 100, 102, 104, 106, 108, 110, 112, 114, 116, 118, 120, 122, 124, 126, 128, 130, 132, 134, 136, 138, 140, 142, 144, 146, 148, 150, 152, 154, 156, 158, 160, 162, 164, 166, 168, 170, 172, 174, 176, 178, 180, 182, 184, 186, 188, 190, 192, 194, 196, 198, 200, 202, 204, 206, 208, 210, 212, 214, 216, 218, 220, 222, 224, 226, 228, 230, 232, 234, 236, 238, 240, 242, 244, 246, 248, 250, 252, 254, 256, 258, 260, 262, 264, 266, 268, 270, 272, 274, 276, 278, 280, 282, 284, 286, 288, 290, 292, 294, 296, or 298. In one example, the present disclosure refers to the modified galactose oxidase disclosed herein, wherein the polypeptide sequence of the modified galactose oxidase has at least 85%, 86%, 87%, 88%, 89%, 90%, 91%, 92%, 93%, 94%, 95%, 96%, 97%, 98%, or 99% sequence identity to the sequence set forth in SEQ ID NO: 8. In one example, the present disclosure refers to the modified galactose oxidase disclosed herein, wherein the polypeptide sequence of the modified galactose oxidase has at least 85%, 86%, 87%, 88%, 89%, 90%, 91%, 92%, 93%, 94%, 95%, 96%, 97%, 98%, or 99% sequence identity to the sequence set forth in SEQ ID NO: 10. In one example, the present disclosure refers to the modified galactose oxidase disclosed herein, wherein the polypeptide sequence of the modified galactose oxidase has at least 85%, 86%, 87%, 88%, 89%, 90%, 91%, 92%, 93%, 94%, 95%, 96%, 97%, 98%, or 99% sequence identity to the sequence set forth in SEQ ID NO: 12. In one example, the present disclosure refers to the modified galactose oxidase disclosed herein, wherein the polypeptide sequence of the modified galactose oxidase has at least 85%, 86%, 87%, 88%, 89%, 90%, 91%, 92%, 93%, 94%, 95%, 96%, 97%, 98%, or 99% sequence identity to the sequence set forth in SEQ ID NO: 14. In one example, the present disclosure refers to the modified galactose oxidase disclosed herein, wherein the polypeptide sequence of the modified galactose oxidase has at least 85%, 86%, 87%, 88%, 89%, 90%, 91%, 92%, 93%, 94%, 95%, 96%, 97%, 98%, or 99% sequence identity to the sequence set forth in SEQ ID NO: 16. In one example, the present disclosure refers to the modified galactose oxidase disclosed herein, wherein the polypeptide sequence of the modified galactose oxidase has at least 85%, 86%, 87%, 88%, 89%, 90%, 91%, 92%, 93%, 94%, 95%, 96%, 97%, 98%, or 99% sequence identity to the sequence set forth in SEQ ID NO: 18. In one example, the present disclosure refers to the modified galactose oxidase disclosed herein, wherein the polypeptide sequence of the modified galactose oxidase has at least 85%, 86%, 87%, 88%, 89%, 90%, 91%, 92%, 93%, 94%, 95%, 96%, 97%, 98%, or 99% sequence identity to the sequence set forth in SEQ ID NO: 20. In one example, the present disclosure refers to the modified galactose oxidase disclosed herein, wherein the polypeptide sequence of the modified galactose oxidase has at least 85%, 86%, 87%, 88%, 89%, 90%, 91%, 92%, 93%, 94%, 95%, 96%, 97%, 98%, or 99% sequence identity to the sequence set forth in SEQ ID NO: 40. In one example, the present disclosure refers to the modified galactose oxidase disclosed herein, wherein the polypeptide sequence of the modified galactose oxidase has at least 85%, 86%, 87%, 88%, 89%, 90%, 91%, 92%, 93%, 94%, 95%, 96%, 97%, 98%, or 99% sequence identity to the sequence set forth in SEQ ID NO: 60. In one example, the present disclosure refers to the modified galactose oxidase disclosed herein, wherein the polypeptide sequence of the modified galactose oxidase has at least 85%, 86%, 87%, 88%, 89%, 90%, 91%, 92%, 93%, 94%, 95%, 96%, 97%, 98%, or 99% sequence identity to the sequence set forth in SEQ ID NO: 80. In one example, the present disclosure refers to the modified galactose oxidase disclosed herein, wherein the polypeptide sequence of the modified galactose oxidase has at least 85%, 86%, 87%, 88%, 89%, 90%, 91%, 92%, 93%, 94%, 95%, 96%, 97%, 98%, or 99% sequence identity to the sequence set forth in SEQ ID NO: 100. In one example, the present disclosure refers to the modified galactose oxidase disclosed herein, wherein the polypeptide sequence of the modified galactose oxidase has at least 85%, 86%, 87%, 88%, 89%, 90%, 91%, 92%, 93%, 94%, 95%, 96%, 97%, 98%, or 99% sequence identity to the sequence set forth in SEQ ID NO: 150. In one example, the present disclosure refers to the modified galactose oxidase disclosed herein, wherein the polypeptide sequence of the modified galactose oxidase has at least 85%, 86%, 87%, 88%, 89%, 90%, 91%, 92%, 93%, 94%, 95%, 96%, 97%, 98%, or 99% sequence identity to the sequence set forth in SEQ ID NO: 200. In one example, the present disclosure refers to the modified galactose oxidase disclosed herein, wherein the polypeptide sequence of the modified galactose oxidase has at least 85%, 86%, 87%, 88%, 89%, 90%, 91%, 92%, 93%, 94%, 95%, 96%, 97%, 98%, or 99% sequence identity to the sequence set forth in SEQ ID NO: 250. In one example, the present disclosure refers to the modified galactose oxidase disclosed herein, wherein the polypeptide sequence of the modified galactose oxidase has at least 85%, 86%, 87%, 88%, 89%, 90%, 91%, 92%, 93%, 94%, 95%, 96%, 97%, 98%, or 99% sequence identity to the sequence set forth in SEQ ID NO: 298.

[0208] In one example, the present disclosure refers to the modified galactose oxidase disclosed herein, wherein the polypeptide sequence of the modified galactose oxidase comprises a polypeptide sequence set forth in the even numbered sequences of SEQ ID NOS: 7-298. In one example, the present disclosure refers to the modified galactose oxidase disclosed herein, wherein the polypeptide sequence of the modified galactose oxidase comprises a polypeptide sequence set forth in the following even numbered sequences: SEQ ID NOS: 8, 10, 12, 14, 16, 18, 20, 22, 24, 26, 28, 30, 32, 34, 36, 38, 40, 42, 44, 46, 48, 50, 52, 54, 56, 58, 60, 62, 64, 66, 68, 70, 72, 74, 76, 78, 80, 82, 84, 86, 88, 90, 92, 94, 96, 98, 100, 102, 104, 106, 108, 110, 112, 114, 116, 118, 120, 122, 124, 126, 128, 130, 132, 134, 136, 138, 140, 142, 144, 146, 148, 150, 152, 154, 156, 158, 160, 162, 164, 166, 168, 170, 172, 174, 176, 178, 180, 182, 184, 186, 188, 190, 192, 194, 196, 198, 200, 202, 204, 206, 208, 210, 212, 214, 216, 218, 220, 222, 224, 226, 228, 230, 232, 234, 236, 238, 240, 242, 244, 246, 248, 250, 252, 254, 256, 258, 260, 262, 264, 266, 268, 270, 272, 274, 276, 278, 280, 282, 284, 286, 288, 290, 292, 294, 296, or 298. In one example, the present disclosure refers to the modified galactose oxidase disclosed herein, wherein the polypeptide sequence of the modified galactose oxidase comprises a polypeptide sequence set forth in SEQ ID NO: 8. In one example, the present disclosure refers to the modified galactose oxidase disclosed herein, wherein the polypeptide sequence of the modified galactose oxidase comprises a polypeptide sequence set forth in SEQ ID NO: 10. In one example, the present disclosure refers to the modified galactose oxidase disclosed herein, wherein the polypeptide sequence of the modified galactose oxidase comprises a polypeptide sequence set forth in SEQ ID NO: 12. In one example, the present disclosure refers to the modified galactose oxidase disclosed herein, wherein the polypeptide sequence of the modified galactose oxidase comprises a polypeptide sequence set forth in SEQ ID NO: 14. In one example, the present disclosure refers to the modified galactose oxidase disclosed herein, wherein the polypeptide sequence of the modified galactose oxidase comprises a polypeptide sequence set forth in SEQ ID NO: 16. In one example, the present disclosure refers to the modified galactose oxidase disclosed herein, wherein the polypeptide sequence of the modified galactose oxidase comprises a polypeptide sequence set forth in SEQ ID NO: 18. In one example, the present disclosure refers to the modified galactose oxidase disclosed herein, wherein the polypeptide sequence of the modified galactose oxidase comprises a polypeptide sequence set forth in SEQ ID NO: 20. In one example, the present disclosure refers to the modified galactose oxidase disclosed herein, wherein the polypeptide sequence of the modified galactose oxidase comprises a polypeptide sequence set forth in SEQ ID NO: 40. In one example, the present disclosure refers to the modified galactose oxidase disclosed herein, wherein the polypeptide sequence of the modified galactose oxidase comprises a polypeptide sequence set forth in SEQ ID NO: 60. In one example, the present disclosure refers to the modified galactose oxidase disclosed herein, wherein the polypeptide sequence of the modified galactose oxidase comprises a polypeptide sequence set forth in SEQ ID NO: 80. In one example, the present disclosure refers to the modified galactose oxidase disclosed herein, wherein the polypeptide sequence of the modified galactose oxidase comprises a polypeptide sequence set forth in SEQ ID NO: 100. In one example, the present disclosure refers to the modified galactose oxidase disclosed herein, wherein the polypeptide sequence of the modified galactose oxidase comprises a polypeptide sequence set forth in SEQ ID NO: 150. In one example, the present disclosure refers to the modified galactose oxidase disclosed herein, wherein the polypeptide sequence of the modified galactose oxidase comprises a polypeptide sequence set forth in SEQ ID NO: 200. In one example, the present disclosure refers to the modified galactose oxidase disclosed herein, wherein the polypeptide sequence of the modified galactose oxidase comprises a polypeptide sequence set forth in SEQ ID NO: 250. In one example, the present disclosure refers to the modified galactose oxidase disclosed herein, wherein the polypeptide sequence of the modified galactose oxidase comprises a polypeptide sequence set forth in SEQ ID NO: 298.

[0209] In one example, the present disclosure refers to the modified galactose oxidase disclosed herein, wherein the mutation is selected from the group consisting of: [0210] (a) S314C; [0211] (b) N268W; [0212] (c) F217A; [0213] (d) a combination of F217A and N268W; [0214] (e) a combination of F217A, N268W and A195S; [0215] (f) a combination of F217A, N268W and N259T; [0216] (g) a combination of F217A, N268W and A195T; [0217] (h) a combination of F217A, N268W and A198I; [0218] (i) a combination of F217A, N268W and T202I; [0219] (j) a combination of F217A, N268W and Y352W; [0220] (k) a combination of F217A, N268W and A24H; [0221] (l) a combination of F217A, N268W and I28R; [0222] (m) a combination of F217A, N268W and D239E; [0223] (n) a combination of F217A, N268W and A24N; [0224] (o) a combination of F217A, N268W and E218K; [0225] (p) a combination of F217A, N268W and E218F; [0226] (q) a combination of F217A, N268W and Y599M; [0227] (r) a combination of F217A, N268W and L226Q; [0228] (s) a combination of F217A, N268W and A195V; [0229] (t) a combination of F217A, N268W, A195T and Y352W; [0230] (u) a combination of F217A, N268W, I28R and K389I; [0231] (v) a combination of F217A, N268W, I28R, A195T, N259T, and K389I; and [0232] (w) a combination of F217A, N268W, I28R, A195T, N259T, N341W, and K389I.

[0233] In one example, the present disclosure refers to the modified galactose oxidase disclosed herein, wherein the modified galactose oxidase comprises the mutations of F217A and N268W.

[0234] In one example, the present disclosure refers to the modified galactose oxidase disclosed herein, wherein the polypeptide sequence of the modified galactose oxidase has at least 85%, 86%, 87%, 88%, 89%, 90%, 91%, 92%, 93%, 94%, 95%, 96%, 97%, 98%, or 99% sequence identity to SEQ ID NO:68.

[0235] In one example, the present disclosure refers to the modified galactose oxidase disclosed herein, wherein the modified galactose oxidase further comprises at least one mutation selected from the group consisting of A24H, A24N, A26H, A26R, I28F, I28M, I28R, Q45D, Q45E, Q45N, E49K, F65P, N69D, N69E, N69F, N69H, N69L, N69M, N69T, N69W, N69Y, W104G, W104N, S114N, S114R, T117D, T153K, T153R, G157N, S172E, S173K, S173R, T175E, T175H, T175I, T175K, V193T, P194C, A195SX, A195T, A195V, A197C, A197G, A198I, T202D, T202I, T202K, T202Q, N214R, N214S, E218F, E218K, E218P, E218Y, S220T, I224W, L226Q, L226V, D239E, D239P, D239Q, R240G, F250E, F250Y, N259T, T265S, D269N, I284S, I284Y, G294A, F313R, S314C, Y325F, N341W, A346L, K348S, Y352T, Y352W, M353F, N356K, N356R, N356W, K389I, A401D, T429W, T447A, I485A, I485K, I485R, F487R, L537G, C538K, C538R, F546M, S559P, S576D, Y599M, Q662D, and Q662P, wherein the position of the mutation is numbered with reference to SEQ ID NO: 6.

[0236] In one example, the present disclosure refers to the modified galactose oxidase disclosed herein, wherein the polypeptide sequence of the modified galactose oxidase has at least 85%, 86%, 87%, 88%, 89%, 90%, 91%, 92%, 93%, 94%, 95%, 96%, 97%, 98%, or 99% sequence identity to the sequence of at least one modified galactose oxidase variant set forth in SEQ ID NOS: 70, 72 or the even numbered sequences of SEQ ID NOS: 77-298. In one example, the present disclosure refers to the modified galactose oxidase disclosed herein, wherein the polypeptide sequence of the modified galactose oxidase has at least 85%, 86%, 87%, 88%, 89%, 90%, 91%, 92%, 93%, 94%, 95%, 96%, 97%, 98%, or 99% sequence identity to the sequence set forth in SEQ ID NO: 70. In one example, the present disclosure refers to the modified galactose oxidase disclosed herein, wherein the polypeptide sequence of the modified galactose oxidase has at least 85%, 86%, 87%, 88%, 89%, 90%, 91%, 92%, 93%, 94%, 95%, 96%, 97%, 98%, or 99% sequence identity to the sequence set forth in SEQ ID NO: 72. In one example, the present disclosure refers to the modified galactose oxidase disclosed herein, wherein the polypeptide sequence of the modified galactose oxidase has at least 85%, 86%, 87%, 88%, 89%, 90%, 91%, 92%, 93%, 94%, 95%, 96%, 97%, 98%, or 99% sequence identity to the sequence of at least one modified galactose oxidase variant set forth in the following even numbered sequences: SEQ ID NOS: 78, 80, 82, 84, 86, 88, 90, 92, 94, 96, 98, 100, 102, 104, 106, 108, 110, 112, 114, 116, 118, 120, 122, 124, 126, 128, 130, 132, 134, 136, 138, 140, 142, 144, 146, 148, 150, 152, 154, 156, 158, 160, 162, 164, 166, 168, 170, 172, 174, 176, 178, 180, 182, 184, 186, 188, 190, 192, 194, 196, 198, 200, 202, 204, 206, 208, 210, 212, 214, 216, 218, 220, 222, 224, 226, 228, 230, 232, 234, 236, 238, 240, 242, 244, 246, 248, 250, 252, 254, 256, 258, 260, 262, 264, 266, 268, 270, 272, 274, 276, 278, 280, 282, 284, 286, 288, 290, 292, 294, 296, or 298. In one example, the present disclosure refers to the modified galactose oxidase disclosed herein, wherein the polypeptide sequence of the modified galactose oxidase has at least 85%, 86%, 87%, 88%, 89%, 90%, 91%, 92%, 93%, 94%, 95%, 96%, 97%, 98%, or 99% sequence identity to the sequence set forth in SEQ ID NO: 78. In one example, the present disclosure refers to the modified galactose oxidase disclosed herein, wherein the polypeptide sequence of the modified galactose oxidase has at least 85%, 86%, 87%, 88%, 89%, 90%, 91%, 92%, 93%, 94%, 95%, 96%, 97%, 98%, or 99% sequence identity to the sequence set forth in SEQ ID NO: 80. In one example, the present disclosure refers to the modified galactose oxidase disclosed herein, wherein the polypeptide sequence of the modified galactose oxidase has at least 85%, 86%, 87%, 88%, 89%, 90%, 91%, 92%, 93%, 94%, 95%, 96%, 97%, 98%, or 99% sequence identity to the sequence set forth in SEQ ID NO: 90. In one example, the present disclosure refers to the modified galactose oxidase disclosed herein, wherein the polypeptide sequence of the modified galactose oxidase has at least 85%, 86%, 87%, 88%, 89%, 90%, 91%, 92%, 93%, 94%, 95%, 96%, 97%, 98%, or 99% sequence identity to the sequence set forth in SEQ ID NO: 90. In one example, the present disclosure refers to the modified galactose oxidase disclosed herein, wherein the polypeptide sequence of the modified galactose oxidase has at least 85%, 86%, 87%, 88%, 89%, 90%, 91%, 92%, 93%, 94%, 95%, 96%, 97%, 98%, or 99% sequence identity to the sequence set forth in SEQ ID NO: 100. In one example, the present disclosure refers to the modified galactose oxidase disclosed herein, wherein the polypeptide sequence of the modified galactose oxidase has at least 85%, 86%, 87%, 88%, 89%, 90%, 91%, 92%, 93%, 94%, 95%, 96%, 97%, 98%, or 99% sequence identity to the sequence set forth in SEQ ID NO: 120. In one example, the present disclosure refers to the modified galactose oxidase disclosed herein, wherein the polypeptide sequence of the modified galactose oxidase has at least 85%, 86%, 87%, 88%, 89%, 90%, 91%, 92%, 93%, 94%, 95%, 96%, 97%, 98%, or 99% sequence identity to the sequence set forth in SEQ ID NO: 140. In one example, the present disclosure refers to the modified galactose oxidase disclosed herein, wherein the polypeptide sequence of the modified galactose oxidase has at least 85%, 86%, 87%, 88%, 89%, 90%, 91%, 92%, 93%, 94%, 95%, 96%, 97%, 98%, or 99% sequence identity to the sequence set forth in SEQ ID NO: 160. In one example, the present disclosure refers to the modified galactose oxidase disclosed herein, wherein the polypeptide sequence of the modified galactose oxidase has at least 85%, 86%, 87%, 88%, 89%, 90%, 91%, 92%, 93%, 94%, 95%, 96%, 97%, 98%, or 99% sequence identity to the sequence set forth in SEQ ID NO: 180. In one example, the present disclosure refers to the modified galactose oxidase disclosed herein, wherein the polypeptide sequence of the modified galactose oxidase has at least 85%, 86%, 87%, 88%, 89%, 90%, 91%, 92%, 93%, 94%, 95%, 96%, 97%, 98%, or 99% sequence identity to the sequence set forth in SEQ ID NO: 200. In one example, the present disclosure refers to the modified galactose oxidase disclosed herein, wherein the polypeptide sequence of the modified galactose oxidase has at least 85%, 86%, 87%, 88%, 89%, 90%, 91%, 92%, 93%, 94%, 95%, 96%, 97%, 98%, or 99% sequence identity to the sequence set forth in SEQ ID NO: 250. In one example, the present disclosure refers to the modified galactose oxidase disclosed herein, wherein the polypeptide sequence of the modified galactose oxidase has at least 85%, 86%, 87%, 88%, 89%, 90%, 91%, 92%, 93%, 94%, 95%, 96%, 97%, 98%, or 99% sequence identity to the sequence set forth in SEQ ID NO: 298.

[0237] In one example, the present disclosure refers to the modified galactose oxidase disclosed herein, wherein the polypeptide sequence of the modified galactose oxidase comprises a polypeptide sequence set forth in SEQ ID NOS: 70, 72 or the even numbered sequences of SEQ ID NOS: 77-298. In one example, the present disclosure refers to the modified galactose oxidase disclosed herein, wherein the polypeptide sequence of the modified galactose oxidase comprises a polypeptide sequence set forth in SEQ ID NO: 70. In one example, the present disclosure refers to the modified galactose oxidase disclosed herein, wherein the polypeptide sequence of the modified galactose oxidase comprises a polypeptide sequence set forth in SEQ ID NO: 72. In one example, the present disclosure refers to the modified galactose oxidase disclosed herein, wherein the polypeptide sequence of the modified galactose oxidase comprises a polypeptide sequence set forth in the following even numbered sequences: SEQ ID NOS: 78, 80, 82, 84, 86, 88, 90, 92, 94, 96, 98, 100, 102, 104, 106, 108, 110, 112, 114, 116, 118, 120, 122, 124, 126, 128, 130, 132, 134, 136, 138, 140, 142, 144, 146, 148, 150, 152, 154, 156, 158, 160, 162, 164, 166, 168, 170, 172, 174, 176, 178, 180, 182, 184, 186, 188, 190, 192, 194, 196, 198, 200, 202, 204, 206, 208, 210, 212, 214, 216, 218, 220, 222, 224, 226, 228, 230, 232, 234, 236, 238, 240, 242, 244, 246, 248, 250, 252, 254, 256, 258, 260, 262, 264, 266, 268, 270, 272, 274, 276, 278, 280, 282, 284, 286, 288, 290, 292, 294, 296, or 298. In one example, the present disclosure refers to the modified galactose oxidase disclosed herein, wherein the polypeptide sequence of the modified galactose oxidase comprises a polypeptide sequence set forth in SEQ ID NO: 78. In one example, the present disclosure refers to the modified galactose oxidase disclosed herein, wherein the polypeptide sequence of the modified galactose oxidase comprises a polypeptide sequence set forth in SEQ ID NO: 80. In one example, the present disclosure refers to the modified galactose oxidase disclosed herein, wherein the polypeptide sequence of the modified galactose oxidase comprises a polypeptide sequence set forth in SEQ ID NO: 90. In one example, the present disclosure refers to the modified galactose oxidase disclosed herein, wherein the polypeptide sequence of the modified galactose oxidase comprises a polypeptide sequence set forth in SEQ ID NO: 100. In one example, the present disclosure refers to the modified galactose oxidase disclosed herein, wherein the polypeptide sequence of the modified galactose oxidase comprises a polypeptide sequence set forth in SEQ ID NO: 120. In one example, the present disclosure refers to the modified galactose oxidase disclosed herein, wherein the polypeptide sequence of the modified galactose oxidase comprises a polypeptide sequence set forth in SEQ ID NO: 140. In one example, the present disclosure refers to the modified galactose oxidase disclosed herein, wherein the polypeptide sequence of the modified galactose oxidase comprises a polypeptide sequence set forth in SEQ ID NO: 160. In one example, the present disclosure refers to the modified galactose oxidase disclosed herein, wherein the polypeptide sequence of the modified galactose oxidase comprises a polypeptide sequence set forth in SEQ ID NO: 180. In one example, the present disclosure refers to the modified galactose oxidase disclosed herein, wherein the polypeptide sequence of the modified galactose oxidase comprises a polypeptide sequence set forth in SEQ ID NO: 200. In one example, the present disclosure refers to the modified galactose oxidase disclosed herein, wherein the polypeptide sequence of the modified galactose oxidase comprises a polypeptide sequence set forth in SEQ ID NO: 250. In one example, the present disclosure refers to the modified galactose oxidase disclosed herein, wherein the polypeptide sequence of the modified galactose oxidase comprises a polypeptide sequence set forth in SEQ ID NO: 298.

[0238] In one example, the present disclosure refers to the modified galactose oxidase disclosed herein, wherein the modified galactose oxidase comprises one or more of the following properties: [0239] (a) enhanced protein expression by at least 1.01-fold compared to the galactose oxidase variant M3-5 or by at least 1.01-fold compared to the modified galactose oxidase disclosed herein; [0240] (b) enhanced solubility by at least 1.01-fold compared to the galactose oxidase variant M3-5 or by at least 1.01-fold compared to the modified galactose oxidase disclosed herein; [0241] (c) enhanced thermal stability by at least 1.01-fold compared to the galactose oxidase variant M3-5 or by at least 1.01-fold compared to the modified galactose oxidase disclosed herein at a temperature of at least 50 C.; [0242] (d) increased enzymatic activity by at least 1.01-fold compared to the galactose oxidase variant M3-5 or by at least 1.01-fold compared to the modified galactose oxidase disclosed herein, wherein the enzymatic activity comprises converting a secondary alcohol to a ketone, wherein optionally the secondary alcohol is a bulky secondary alcohol or unactivated secondary alcohol; and [0243] (e) reduced enantioselectivity by at least 1.01-fold compared to the galactose oxidase variant M3-5 or by at least 1.01-fold compared to the modified galactose oxidase disclosed herein.

[0244] In one example, the present disclosure refers to the modified galactose oxidase disclosed herein, wherein the modified galactose oxidase has enhanced protein expression by at least 1.01-fold compared to the galactose oxidase variant M3-5 or by at least 1.01-fold compared to the modified galactose oxidase variant GOh1052 that has F217A and N268W mutations. In one example, the modified galactose oxidase has enhanced protein expression by about 1.01 to 1.73-fold compared to the galactose oxidase variant M3-5. In one example, the modified galactose oxidase has enhanced protein expression by at least about 1.06-fold compared to the galactose oxidase variant M3-5. In one example, the modified galactose oxidase has enhanced protein expression by at least about 1.1-fold compared to the galactose oxidase variant M3-5. In one example, the modified galactose oxidase has enhanced protein expression by at least about 1.2-fold compared to the galactose oxidase variant M3-5. In one example, the modified galactose oxidase has enhanced protein expression by at least about 1.3-fold compared to the galactose oxidase variant M3-5. In one example, the modified galactose oxidase has enhanced protein expression by at least about 1.4-fold compared to the galactose oxidase variant M3-5. In one example, the modified galactose oxidase has enhanced protein expression by at least about 1.5-fold compared to the galactose oxidase variant M3-5. In one example, the modified galactose oxidase has enhanced protein expression by at least about 1.6-fold compared to the galactose oxidase variant M3-5. In one example, the modified galactose oxidase has enhanced protein expression by at least about 1.7-fold compared to the galactose oxidase variant M3-5. In one example, the modified galactose oxidase has enhanced protein expression by about 1.01 to 10.09-fold compared to the galactose oxidase variant GOh1052. In one example, the modified galactose oxidase has enhanced protein expression by at least about 1.01-fold compared to the galactose oxidase variant GOh1052. In one example, the modified galactose oxidase has enhanced protein expression by at least about 2-fold compared to the galactose oxidase variant GOh1052. In one example, the modified galactose oxidase has enhanced protein expression by at least about 3-fold compared to the galactose oxidase variant GOh1052. In one example, the modified galactose oxidase has enhanced protein expression by at least about 4-fold compared to the galactose oxidase variant GOh1052. In one example, the modified galactose oxidase has enhanced protein expression by at least about 5-fold compared to the galactose oxidase variant GOh1052. In one example, the modified galactose oxidase has enhanced protein expression by at least about 6-fold compared to the galactose oxidase variant GOh1052. In one example, the modified galactose oxidase has enhanced protein expression by at least about 7-fold compared to the galactose oxidase variant GOh1052. In one example, the modified galactose oxidase has enhanced protein expression by at least about 8-fold compared to the galactose oxidase variant GOh1052. In one example, the modified galactose oxidase has enhanced protein expression by at least about 9-fold compared to the galactose oxidase variant GOh1052. In one example, the modified galactose oxidase has enhanced protein expression by at least about 10-fold compared to the galactose oxidase variant GOh1052. In one example, the modified galactose oxidase has enhanced protein expression by at least about 10-fold compared to the galactose oxidase variant GOh1052. In one specific example, the modified galactose oxidase has enhanced protein expression by at least 1.51-fold compared to the galactose oxidase variant M3-5. In one specific example, the modified galactose oxidase has enhanced protein expression by at least 2.58-fold compared to the galactose oxidase variant GOh1052. In one specific example, the modified galactose oxidase has enhanced protein expression by at least 4.29-fold compared to the galactose oxidase variant GOh1052.

[0245] In one example, the present disclosure refers to the modified galactose oxidase disclosed herein, wherein the modified galactose oxidase has enhanced solubility by at least 1.01-fold compared to the galactose oxidase variant M3-5 or by at least 1.01-fold compared to the modified galactose oxidase variant GOh1052 that has the F217A and N268W mutations. In one example, the modified galactose oxidase has enhanced solubility by about 1.01 to 1.67-fold compared to the galactose oxidase variant M3-5. In one example, the modified galactose oxidase has enhanced solubility by at least about 1.1-fold compared to the galactose oxidase variant M3-5. In one example, the modified galactose oxidase has enhanced solubility by at least about 1.2-fold compared to the galactose oxidase variant M3-5. In one example, the modified galactose oxidase has enhanced solubility by at least about 1.3-fold compared to the galactose oxidase variant M3-5. In one example, the modified galactose oxidase has enhanced solubility by at least about 1.4-fold compared to the galactose oxidase variant M3-5. In one example, the modified galactose oxidase has enhanced solubility by at least about 1.5-fold compared to the galactose oxidase variant M3-5. In one example, the modified galactose oxidase has enhanced solubility by at least about 1.6-fold compared to the galactose oxidase variant M3-5. In one specific example, the modified galactose oxidase has enhanced solubility by at least about 1.13-fold compared to the galactose oxidase variant M3-5. In one example, the modified galactose oxidase has enhanced solubility by about 1.01 to 4.57-fold compared to the galactose oxidase variant GOh1052. In one example, the modified galactose oxidase has enhanced solubility by at least about 1.01-fold compared to the galactose oxidase variant GOh1052. In one example, the modified galactose oxidase has enhanced solubility by at least about 1.02-fold compared to the galactose oxidase variant GOh1052. In one example, the modified galactose oxidase has enhanced solubility by at least about 2-fold compared to the galactose oxidase variant GOh1052. In one example, the modified galactose oxidase has enhanced solubility by at least about 3-fold compared to the galactose oxidase variant GOh1052. In one example, the modified galactose oxidase has enhanced solubility by at least about 4-fold compared to the galactose oxidase variant GOh1052. In one specific example, the modified galactose oxidase has enhanced solubility by at least about 1.01-fold compared to the galactose oxidase variant GOh1052. In one specific example, the modified galactose oxidase has enhanced solubility by at least about 2.82-fold compared to the galactose oxidase variant GOh1052. In one specific example, the modified galactose oxidase has enhanced solubility by at least about 4.57-fold compared to the galactose oxidase variant GOh1052. In one example, solubility of the galactose oxidase variant is determined using the ratio of protein expression of soluble proteins over insoluble proteins. The higher the value, the more soluble it is. Solubility is then compared against either M3-5 (SEQ ID NO.: 6) or GOh1052 (SEQ ID NO.: 68), where the fold improvement is determined.

[0246] In one example, the present disclosure refers to the modified galactose oxidase disclosed herein, wherein the modified galactose oxidase has enhanced thermal stability by at least 1.01-fold compared to the modified galactose oxidase variant GOh1052 that has F217A and N268W mutations at a temperature of at least 50 C. or by at least 1.52-fold compared to the modified galactose oxidase variant M3-5 at a temperature of at least 55 C. In one example, the modified galactose oxidase has enhanced thermal stability by about 1.52 to 1.61-fold compared to the galactose oxidase variant M3-5. In one example, the modified galactose oxidase has enhanced thermal stability by at least about 1.6-fold compared to the galactose oxidase variant M3-5. In one specific example, the modified galactose oxidase has enhanced thermal stability by at least about 1.52-fold compared to the galactose oxidase variant M3-5. In one example, the modified galactose oxidase has enhanced thermal stability by about 1.01 to 1.61-fold compared to the galactose oxidase variant GOh1052. In one example, the modified galactose oxidase has enhanced thermal stability by at least about 1.01-fold compared to the galactose oxidase variant GOh1052. In one example, the modified galactose oxidase has enhanced thermal stability by at least about 1.1-fold compared to the galactose oxidase variant GOh1052. In one example, the modified galactose oxidase has enhanced thermal stability by at least about 1.2-fold compared to the galactose oxidase variant GOh1052. In one example, the modified galactose oxidase has enhanced thermal stability by at least about 1.3-fold compared to the galactose oxidase variant GOh1052. In one example, the modified galactose oxidase has enhanced thermal stability by at least about 1.4-fold compared to the galactose oxidase variant GOh1052. In one example, the modified galactose oxidase has enhanced thermal stability by at least about 1.5-fold compared to the galactose oxidase variant GOh1052. In one example, the modified galactose oxidase has enhanced thermal stability by at least about 1.6-fold compared to the galactose oxidase variant GOh1052. In one specific example, the modified galactose oxidase has enhanced thermal stability by at least about 1.50-fold compared to the galactose oxidase variant GOh1052. In one specific example, the modified galactose oxidase has enhanced thermal stability by at least about 1.61-fold compared to the galactose oxidase variant GOh1052. In one example, thermal stability of the galactose oxidase variants is tested using a two-phase approach. In one example, higher temperatures of 50 C. and 55 C. were tested in the two-phase approach by: (1) heating the enzyme at temperature for 30 minutes and then followed by (2) a contacting step of the heated enzyme and substrate combined at 25 C. for a specified reaction time, typically for 24 hours. In one example, 50 C. was the temperature at which the enzymes were incubated at for 30 minutes before being used in the standard 25 C. activity assay, which was done to assess thermal stability of the enzyme by comparison of the thermally challenged activity against enzyme activity that was not thermally challenged. In one example, 55 C. was the temperature at which the enzymes were incubated at for 30 minutes before being used in the standard 25 C. activity assay, which was done to assess thermal stability of the enzyme by comparison of the thermally challenged activity against enzyme activity that was not thermally challenged. These are distinct from the 40 C. activity assay, which is an activity assay conducted at higher temperatures to assess enzyme performance at higher temperatures. Although it can also be taken as a measure of thermal stability, the measure used to assess thermal stability was the former (50 C. for 30 minutes thermal challenge assay).

[0247] In one example, the present disclosure refers to the modified galactose oxidase disclosed herein, wherein the modified galactose oxidase has increased enzymatic activity by at least 1.01-fold compared to the galactose oxidase variant M3-5 or by at least 1.01-fold compared to the modified galactose oxidase variant GOh1052 that has F217A and N268W mutations, wherein the enzymatic activity comprises converting a secondary alcohol to a ketone, wherein optionally the secondary alcohol is a bulky secondary alcohol or unactivated secondary alcohol. In one example, the modified galactose oxidase has increased enzymatic activity by at least 1.1-fold compared to the galactose oxidase variant M3-5. In one example, the modified galactose oxidase has increased enzymatic activity by at least 2-fold compared to the galactose oxidase variant M3-5. In one example, the modified galactose oxidase has increased enzymatic activity by at least 3-fold compared to the galactose oxidase variant M3-5. In one example, the modified galactose oxidase has increased enzymatic activity by at least 4-fold compared to the galactose oxidase variant M3-5. In one example, the modified galactose oxidase has increased enzymatic activity by at least 5-fold compared to the galactose oxidase variant M3-5. In one example, the modified galactose oxidase has increased enzymatic activity by at least 6-fold compared to the galactose oxidase variant M3-5. In one example, the modified galactose oxidase has increased enzymatic activity by at least 7-fold compared to the galactose oxidase variant M3-5. In one example, the modified galactose oxidase has increased enzymatic activity by at least 8-fold compared to the galactose oxidase variant M3-5. In one example, the modified galactose oxidase has increased enzymatic activity by at least 9-fold compared to the galactose oxidase variant M3-5. In one specific example, the modified galactose oxidase has increased enzymatic activity by 1.85-fold compared to the galactose oxidase variant M3-5. In one specific example, the modified galactose oxidase has increased enzymatic activity by 2.18-fold compared to the galactose oxidase variant M3-5. In one specific example, the modified galactose oxidase has increased enzymatic activity by at least 1.5-fold better than M3-5 for Substrate 128 (alpha-tetralol). In one specific example, the modified galactose oxidase has increased enzymatic activity by at least 1.5-fold better than M3-5 for Substrate 128 (alpha-tetralol). In one specific example, the modified galactose oxidase has increased enzymatic activity by at least 1.04-fold better than GOh1052 for substrate 152 (1-phenyl-1-butanol). In one specific example, the modified galactose oxidase has increased enzymatic activity by at least 1.04-fold better than GOh1052 for substrate 152 (1-phenyl-1-butanol). In one specific example, the modified galactose oxidase has increased enzymatic activity by at least 1.01-fold better than M3-5 for 1 or more substrates in the 64-substrate panel in FIG. 1. In one specific example, the modified galactose oxidase has increased enzymatic activity by at least 1.1-fold better than M3-5 for 1 or more substrates in the 64-substrate panel in FIG. 1. In one example, the present disclosure refers to the modified galactose oxidase disclosed herein, wherein the modified galactose oxidase comprises increased enzymatic activity by at least 10-fold compared to the galactose oxidase variant M3-5 or by at least 1.2-fold compared to the modified galactose oxidase disclosed herein, wherein the enzymatic activity comprises converting a secondary alcohol to a ketone, wherein optionally the secondary alcohol is a bulky secondary alcohol or unactivated secondary alcohol.

[0248] In one example, the present disclosure refers to the modified galactose oxidase disclosed herein, reduced enantioselectivity by at least 1.04-fold compared to the galactose oxidase variant M3-5 or by at least 1.15-fold compared to the galactose oxidase variant GOh1052. In one example, the modified galactose oxidase disclosed herein, reduced enantioselectivity by about 1.04 to 12.9-fold compared to the galactose oxidase variant M3-5. In one example, the modified galactose oxidase disclosed herein, reduced enantioselectivity by at least 1.1-fold compared to the galactose oxidase variant M3-5. In one example, the modified galactose oxidase disclosed herein, reduced enantioselectivity by at least 2-fold compared to the galactose oxidase variant M3-5. In one example, the modified galactose oxidase disclosed herein, reduced enantioselectivity by at least 3-fold compared to the galactose oxidase variant M3-5. In one example, the modified galactose oxidase disclosed herein, reduced enantioselectivity by at least 4-fold compared to the galactose oxidase variant M3-5. In one example, the modified galactose oxidase disclosed herein, reduced enantioselectivity by at least 5-fold compared to the galactose oxidase variant M3-5. In one example, the modified galactose oxidase disclosed herein, reduced enantioselectivity by at least 6-fold compared to the galactose oxidase variant M3-5. In one example, the modified galactose oxidase disclosed herein, reduced enantioselectivity by at least 7-fold compared to the galactose oxidase variant M3-5. In one example, the modified galactose oxidase disclosed herein, reduced enantioselectivity by at least 8-fold compared to the galactose oxidase variant M3-5. In one example, the modified galactose oxidase disclosed herein, reduced enantioselectivity by at least 9-fold compared to the galactose oxidase variant M3-5. In one example, the modified galactose oxidase disclosed herein, reduced enantioselectivity by at least 10-fold compared to the galactose oxidase variant M3-5. In one example, the modified galactose oxidase disclosed herein, reduced enantioselectivity by at least 11-fold compared to the galactose oxidase variant M3-5. In one example, the modified galactose oxidase disclosed herein, reduced enantioselectivity by at least 12-fold compared to the galactose oxidase variant M3-5. In one specific example, the modified galactose oxidase disclosed herein, reduced enantioselectivity by 12.9-fold compared to the galactose oxidase variant M3-5. In one specific example, the GOh1XXX modified galactose oxidase disclosed herein, has minimum reduced enantioselectivity of 0.8 R/S ratio from M3-5 experimental value of 20.6 R/S ratio (for substrate 128alpha-tetralol). In one example, the modified galactose oxidase disclosed herein, reduced enantioselectivity by about 1.15 to 1.59-fold compared to the galactose oxidase variant GOh1052. In one example, the modified galactose oxidase disclosed herein, reduced enantioselectivity by at least 1.2-fold compared to the galactose oxidase variant GOh1052. In one example, the modified galactose oxidase disclosed herein, reduced enantioselectivity by at least 1.3-fold compared to the galactose oxidase variant GOh1052. In one example, the modified galactose oxidase disclosed herein, reduced enantioselectivity by at least 1.4-fold compared to the galactose oxidase variant GOh1052. In one example, the modified galactose oxidase disclosed herein, reduced enantioselectivity by at least 1.5-fold compared to the galactose oxidase variant GOh1052. In one specific example, the modified galactose oxidase disclosed herein, reduced enantioselectivity by 1.59-fold compared to the galactose oxidase variant GOh1052. In one specific example, the GOh2XXX and GOh3XXX modified galactose oxidase disclosed herein, has minimum reduced enantioselectivity of 1.04 R/S ratio from M3-5 (for substrate 128alpha-tetralol) or from GOh1052 (for substrate 152-1-phenyl-1-butanol).

[0249] In one aspect, the present disclosure refers to a polynucleotide sequence encoding the modified galactose oxidase disclosed herein.

[0250] In one example, the present disclosure refers to the polynucleotide sequence disclosed herein, wherein the polynucleotide sequence comprises at least 85%, 86%, 87%, 88%, 89%, 90%, 91%, 92%, 93%, 94%, 95%, 96%, 97%, 98%, or 99% or more sequence identity to SEQ ID NO: 5, wherein SEQ ID NO: 5 is a polynucleotide sequence of the galactose oxidase variant M3-5, wherein the polynucleotide sequence disclosed herein comprises at least one mutation at one or more positions which leads to at least one mutation in the polypeptide sequence of the modified galactose oxidase disclosed herein.

[0251] In one example, the present disclosure refers to the polynucleotide sequence disclosed herein, wherein the polynucleotide is codon optimized, wherein optionally the polynucleotide is codon optimized for protein expression in Escherichia coli. In one example, the polynucleotide is codon optimized for protein expression in other types of cells known in the art, such as yeast cells, mammalian cells or other suitable cells known in the art. In one example, the polynucleotide is codon optimized for protein expression in yeast cells such as Saccharomyces cerevisiae and Pichia pastoris. In one example, the polynucleotide is codon optimized for protein expression in mammalian cells such as Chinese Hamster Ovary (CHO) cells. The term codon optimization as used herein, refers to methods to improve codon composition of a polynucleotide without altering the amino acid sequence, since it is known in the art that most amino acids can be encoded by more than one codon.

[0252] In one example, the present disclosure refers to the polynucleotide sequence disclosed herein, wherein the polynucleotide sequence is further linked to a control sequence. In one example, the control sequence is a promoter sequence or a termination sequence. In one example, the promoter sequence is a lac promoter sequence, CMV promoter sequence, SV40 promoter sequence, PBAD promoter sequence, GAL promoter sequence, AOX1 promoter sequence, or other promoter sequences that are well-known in the art. In one example, the PBAD promoter can be used for controlling gene expression in Escherichia coli (E. coli). In one example, the GAL promoter can be used for controlling gene expression in Saccharomyces cerevisiae (S. cerevisiae). In one example, the AOX1 promoter can be used for controlling gene expression in Pichia pastoris (P. pastoris). In one specific example, the promoter sequence is a lac promoter sequence. The term control sequence as used herein refers to a regulatory sequence or regulatory element within a polynucleotide sequence that regulates gene expression. Examples of control sequences that are well-known in the art are promoters, enhancers, repressors, and terminators.

[0253] In one example, the present disclosure refers to the polynucleotide sequence disclosed herein, wherein the polynucleotide comprises an odd numbered sequence of SEQ ID NOS: 7-298. In one example, the present disclosure refers to the polynucleotide sequence disclosed herein, wherein the polynucleotide comprises an odd numbered sequence of SEQ ID NOS: 7, 9, 11, 13, 15, 17, 19, 21, 23, 25, 27, 29, 31, 33, 35, 37, 39, 41, 43, 45, 47, 49, 51, 53, 55, 57, 59, 61, 63, 65, 67, 69, 71, 73, 75, 77, 79, 81, 83, 85, 87, 89, 91, 93, 95, 97, 99, 101, 103, 105, 107, 109, 111, 113, 115, 117, 119, 121, 123, 125, 127, 129, 131, 133, 135, 137, 139, 141, 143, 145, 147, 149, 151, 153, 155, 157, 159, 161, 163, 165, 167, 169, 171, 173, 175, 177, 179, 181, 183, 185, 187, 189, 191, 193, 195, 197, 199, 201, 203, 205, 207, 209, 211, 213, 215, 217, 219, 221, 223, 225, 227, 229, 231, 233, 235, 237, 239, 241, 243, 245, 247, 249, 251, 253, 255, 257, 259, 261, 263, 265, 267, 269, 271, 273, 275, 277, 279, 281, 283, 285, 287, 289, 291, 293, 295, or 297. In one example, the present disclosure refers to the polynucleotide sequence disclosed herein, wherein the polynucleotide comprises the sequence of SEQ ID NO: 7. In one example, the present disclosure refers to the polynucleotide sequence disclosed herein, wherein the polynucleotide comprises the sequence of SEQ ID NO: 9. In one example, the present disclosure refers to the polynucleotide sequence disclosed herein, wherein the polynucleotide comprises the sequence of SEQ ID NO: 11. In one example, the present disclosure refers to the polynucleotide sequence disclosed herein, wherein the polynucleotide comprises the sequence of SEQ ID NO: 13. In one example, the present disclosure refers to the polynucleotide sequence disclosed herein, wherein the polynucleotide comprises the sequence of SEQ ID NO: 15. In one example, the present disclosure refers to the polynucleotide sequence disclosed herein, wherein the polynucleotide comprises the sequence of SEQ ID NO: 17. In one example, the present disclosure refers to the polynucleotide sequence disclosed herein, wherein the polynucleotide comprises the sequence of SEQ ID NO: 19. In one example, the present disclosure refers to the polynucleotide sequence disclosed herein, wherein the polynucleotide comprises the sequence of SEQ ID NO: 21. In one example, the present disclosure refers to the polynucleotide sequence disclosed herein, wherein the polynucleotide comprises the sequence of SEQ ID NO: 31. In one example, the present disclosure refers to the polynucleotide sequence disclosed herein, wherein the polynucleotide comprises the sequence of SEQ ID NO: 41. In one example, the present disclosure refers to the polynucleotide sequence disclosed herein, wherein the polynucleotide comprises the sequence of SEQ ID NO: 51. In one example, the present disclosure refers to the polynucleotide sequence disclosed herein, wherein the polynucleotide comprises the sequence of SEQ ID NO: 61. In one example, the present disclosure refers to the polynucleotide sequence disclosed herein, wherein the polynucleotide comprises the sequence of SEQ ID NO: 71. In one example, the present disclosure refers to the polynucleotide sequence disclosed herein, wherein the polynucleotide comprises the sequence of SEQ ID NO: 81. In one example, the present disclosure refers to the polynucleotide sequence disclosed herein, wherein the polynucleotide comprises the sequence of SEQ ID NO: 91. In one example, the present disclosure refers to the polynucleotide sequence disclosed herein, wherein the polynucleotide comprises the sequence of SEQ ID NO: 101. In one example, the present disclosure refers to the polynucleotide sequence disclosed herein, wherein the polynucleotide comprises the sequence of SEQ ID NO: 151. In one example, the present disclosure refers to the polynucleotide sequence disclosed herein, wherein the polynucleotide comprises the sequence of SEQ ID NO: 201. In one example, the present disclosure refers to the polynucleotide sequence disclosed herein, wherein the polynucleotide comprises the sequence of SEQ ID NO: 251. In one example, the present disclosure refers to the polynucleotide sequence disclosed herein, wherein the polynucleotide comprises the sequence of SEQ ID NO: 297.

[0254] In one aspect, the present disclosure refers an expression vector comprising the polynucleotide sequence disclosed herein. In one example, the expression vector is selected from the group consisting of a plasmid and a viral vector. Suitable expression vectors for production of proteins (such as enzymes, such as the modified galactose oxidase of the present disclosure) are well known to those skilled in the art. Examples of plasmid vectors include pET28a, pcDNA3.1, pGEX, pCMV, pYES, and pGAPZ. In one example, the pYES plasmid vector is designed for protein expression in Saccharomyces cerevisiae (S. cerevisiae). In one example, the pGAPZ plasmid vector is designed for protein expression in Pichia pastoris (P. pastoris). In one specific example, the expression vector is a pET28a plasmid vector. Examples of viral vectors include Adeno-Associated Viral Vector (AAV) and lentiviral vector. In one example, the expression vector comprising the polynucleotide sequence disclosed herein may be vectors generally used for the production of proteins/enzymes which are known to those skilled in the art.

[0255] In one aspect, the present disclosure refers to a host cell comprising the polynucleotide sequence disclosed herein or the expression vector disclosed herein. In one example, the present disclosure refers to a host cell comprising the polynucleotide sequence disclosed herein. In one example, the present disclosure refers to a host cell comprising the expression vector disclosed herein. In one example, the host cell disclosed herein is a prokaryotic cell or eukaryotic cell. In one example, the host cell is a prokaryotic cell. In one specific example, the prokaryotic cell is Escherichia coli. In one example, the host cell comprising the polynucleotide sequence disclosed herein or the expression vector disclosed herein is E. coli BL21(DE3). In one example, the host cell comprising the polynucleotide sequence disclosed herein or the expression vector disclosed herein may be cells generally used for the production of proteins/enzymes which are known to those skilled in the art.

[0256] In one aspect, the present disclosure refers to a method of producing a modified galactose oxidase, comprising culturing the host cell disclosed herein under suitable culture conditions such that the modified galactose oxidase is produced. In one example, the method comprises culturing the host cell disclosed herein in a culture medium. In one example, the culture medium is lysogeny broth (LB) medium supplemented with kanamycin, or any other suitable culture medium known in the art. In one example, the method of producing the modified galactose oxidase disclosed herein, further comprises recovering the modified galactose oxidase from the culture and/or the host cell. In one example, the method of producing the modified galactose oxidase disclosed herein, further comprises recovering the modified galactose oxidase from the culture. In one example, the method of producing the modified galactose oxidase disclosed herein, further comprises recovering the modified galactose oxidase from the host cell. In one example, the method of producing the modified galactose oxidase disclosed herein, further comprises recovering the modified galactose oxidase from the culture and host cell. In one example, the method of recovering the modified galactose oxidase disclosed herein from the culture and host cell are commonly used methods of protein recovery from culture and host cells which are well-known to those skilled in the art. In one example, the modified galactose oxidase disclosed herein is recovered from the culture and host cell through cell harvesting by centrifugation, where the proteins from the culture medium are separated based on density differences. In one example, the modified galactose oxidase disclosed herein is recovered from the culture and host cell through cell harvesting by filtration, whereby culture media are filtered to separate host cells from the culture media using membranes filters. In one example, the modified galactose oxidase disclosed herein is recovered from the culture and host cell through cell lysis/disruption by mechanical or chemical disruption of host cells to disrupt cell walls/membranes and release intracellular proteins. In one example, the method of producing the modified galactose oxidase disclosed herein, further comprises purifying the modified galactose oxidase. In one example, the method of purifying the modified galactose oxidase disclosed herein is by affinity chromatography, using specific affinity tags such as His-tag and GST-tag. In one example, the method of purifying the modified galactose oxidase disclosed herein is by ion exchange chromatography, whereby proteins are separated based on charge differences. In one example, the method of purifying the modified galactose oxidase disclosed herein is by size exclusion chromatography, whereby proteins are separated based on their size and molecular weight. In one specific example, the method of purifying the modified galactose oxidase disclosed herein is by affinity chromatography, using His-tag. In one example, the method of producing and purifying the modified galactose oxidase disclosed herein may be methods generally used for the production and purification of proteins, such as enzymes, which are known to those skilled in the art.

[0257] In one aspect, the present disclosure refers to a method of producing a ketone from a secondary alcohol, comprising contacting the secondary alcohol with the modified galactose oxidase disclosed herein under suitable conditions for an oxidation reaction. In one example, the secondary alcohol is a bulky secondary alcohol or unactivated secondary alcohol. In one example, the secondary alcohol is a bulky secondary alcohol which comprises one or more bulky substituents. In one example, the unactivated secondary alcohol is an aliphatic secondary alcohol without a benzene ring in the alpha position adjacent to the alcohol group.

[0258] In one example, the secondary alcohol comprises the formula R.sup.1R.sup.2CHOH, wherein R.sup.1 and R.sup.2 are independently selected from the group consisting of cycloalkyl, aryl, heteroaryl, alkyl, alkylene, alkynyl, haloalkyl, carboxyl, and carbonyl, wherein the cycloalkyl, aryl, heteroaryl, alkyl, alkylene, alkynyl, haloalkyl, carboxyl, and carbonyl is optionally substituted with one or more substituents selected from the group consisting of alkyl, halogen, alkyl halide, alkylene, alkynyl, alkoxy, cyano, oxo, nitro, amino, thiol, carboxyl, ester and hydroxyl. In one example, the secondary alcohol is selected from the group consisting of:

##STR00002## ##STR00003## ##STR00004## ##STR00005## ##STR00006## ##STR00007##

[0259] In one example, the secondary alcohol is chiral or non-chiral. In one example, the secondary alcohol is chiral. In one example, the secondary alcohol is non-chiral. In one example, the chiral secondary alcohol is present as (S)-enantiomer, (R)-enantiomer, or a mixture of (S)- and (R)-enantiomers. In one example, the chiral secondary alcohol is present as a racemic mixture.

[0260] In one example, the present disclosure refers to a method of producing a ketone from a secondary alcohol, comprising contacting the secondary alcohol with the modified galactose oxidase disclosed herein, wherein the contacting step is performed at a temperature of 25 C., 30 C., 35 C., 40 C., 45 C., 50 C., 55 C. or more. In one example, the contacting step is performed at a temperature of 25 C. In one example, the contacting step is performed at a temperature of 30 C. In one example, the contacting step is performed at a temperature of 35 C. In one example, the contacting step is performed at a temperature of 40 C. In one example, the contacting step is performed at a temperature of 45 C. In one example, the contacting step is performed at a temperature of 50 C. In one example, the contacting step is performed at a temperature of 55 C. In one example, the contacting step is performed at a temperature higher than 55 C. In one example, the contacting step refers to a step where the substrate and the enzyme are first mixed, before the oxidation reaction occurs. In one example, the contacting step is performed at a temperature of 25 C., 30 C., 35 C., 40 C., 45 C., 50 C., 55 C. or more, wherein optionally the temperature is 35 C. In one example, the oxidation reaction can be performed at lower temperatures than 40 C. and can be conducted at 25 C. In some examples, certain galactose oxidase mutants have shown enzymatic activity even after a thermal challenge at 55 C. Optimal temperature for the reaction depends on, for example, enzyme variant, substrate as well as which output variable. Taking GOh1052 variant with substrate 152 (1-phenyl-1-butanol) as an example, although 40 C. is the optimal temperature for fastest initial rate of reaction, 35 C. is preferred over a 24-hour reaction period as it results in higher overall yields (72% at 35 C. vs 55% at 40 C.).

[0261] In one example, the method of producing a ketone from a secondary alcohol disclosed herein, further comprises converting the secondary alcohol into an active pharmaceutical ingredient (API). The term active pharmaceutical ingredient as used herein refers to a biologically active component of a pharmaceutical drug responsible for the therapeutic effect of the drug.

[0262] In one aspect, the present disclosure refers to a kit for use in the method disclosed herein, wherein the kit comprises the modified galactose oxidase disclosed herein. In one example, the kit disclosed herein comprises one or more of the following: (a) one or more reaction buffers; (b) one or more reaction vessels, wherein optionally the reaction vessel is a HPLC vial; (c) one or more reaction solvents, wherein optionally the reaction solvent is 5% v/v dimethyl sulfoxide in 100 mM sodium phosphate buffer with a pH of 7; (d) one or more secondary alcohol substrates; (e) one or more co-enzymes to break down the by-product of the oxidation reaction, wherein optionally the co-enzyme is a horseradish peroxidase that breaks down the H.sub.2O.sub.2; and (f) instructions for performing the method disclosed herein. In one example, the one or more reaction buffer is Jones Reagent. In one example, the one or more reaction buffer is PCC (Pyridinium chlorochromate). In one example, the one or more reaction buffer contains an enzyme capable of catalysing the conversion of secondary alcohols to ketones. In one example, the enzyme is alcohol dehydrogenase. In one example, the one or more reaction buffer contains an enzyme and cofactors. In one example, the enzyme is alcohol dehydrogenase and the cofactor is NAD.sup.+ (nicotinamide adenine dinucleotide) or NADP.sup.+ (nicotinamide adenine dinucleotide phosphate). In some examples, the reagents in the kit as described herein may be provided in separate containers comprising the components independently distributed in one or more containers.

Examples

Methods

Galactose Oxidase Expression in E. coli and Purification

[0263] The wildtype galactose oxidase gene from Fusarium graminearum was synthesized (Twist Bioscience) and cloned into the expression vector pET28a (Novagen) using the NdeI and XhoI restriction sites. Eight additional mutations (S33P, M93V, G218E, W313F, R353M, Q429T, V517A, N558D) were incorporated into the wildtype galactose oxidase gene via splicing by overlap extension (SOE) method to produce GOh1001b variant. The GOh1001b plasmid was then transformed into E. coli BL21(DE3) strain. The E. coli containing the plasmid was grown in 250 mL lysogeny broth (LB) medium with 50 g/mL kanamycin at 37 C. until an absorbance of 0.5 at 600 nm was reached. Overexpression was induced by adding 0.1 mM isopropyl -D-1-thiogalactopyranoside (IPTG) and incubation was continued at 16 C. for 20 hours. Cells were harvested by centrifugation (2,450g for 15 minutes). The cell pellet was resuspended in 12 mL of 100 mM sodium phosphate buffer, pH 7.0 and the cells were lysed using a cell disruptor (Constant Systems) at 40 kPSI. The lysate was then centrifuged, and the clarified supernatant was added to TALON metal affinity resin (Clontech). The supernatant-resin mixture was incubated at 4 C. with rotation for 2 hours. The His-tagged protein bound resin was washed with binding buffer (100 mM sodium phosphate buffer, pH 7.0, 300 mM NaCl, 5 mM imidazole) and eluted with elution buffer (100 mM sodium phosphate buffer, pH 7.0, 300 mM NaCl, 250 mM imidazole). The elution was desalted using PD-10 desalting column (GE Healthcare) in 100 mM sodium phosphate buffer, pH 7.0. The protein concentration was measured using Pierce BCA Protein Assay kit (Thermo Fisher Scientific) against diluted albumin (BSA) standards as provided inside the kit. The purified protein was then diluted to 400 g/mL and activated with 1 mM copper sulphate at 25 C. for 15 minutes.

Codon Optimization for GO01b Variant

[0264] Synthesized gene was ordered from Twist Bioscience. Utilizing their website tool, amino acid sequence was entered, and desired codon usage table selected (E. coli). Twist Bioscience's codon optimization algorithm subsequently provided the DNA nucleotide sequence. Algorithm results are not reproducible as identical amino acid sequences keyed in twice will return different DNA nucleotide sequences.

Library Construction and New Variant Construction

[0265] Round 1: Saturation mutagenesis (NNK) at the actives sites was performed on GOh1001b variant via SOE method to generate libraries for high throughput (HTP) screening. Beneficial mutations from HTP screening were combined via SOE method. [0266] Round 2: Site saturation mutagenesis libraries on GOh1052 variant were ordered from either Twist Bioscience or GenScript with codon usage for E. coli expression at each mutated position only. [0267] Round 3: Beneficial mutations from Round 2 were combined via SOE method on GOh1052 variant. For combinatorial library on GOh1052 variant, oligos with wildtype DNA codon and mutation DNA codon at each position were ordered and pooled together with equal ratio to give a theoretical 50% rate of mutation incorporation. Combinatorial library was constructed via SOE method.

High Throughput Growth and Lysis

[0268] For each NNK library in round 1, 84 colonies for variants (32 codons, 93% coverage), six (6) colonies for GOh1001b variant, and six (6) colonies for negative control (pET28a) were inoculated into a 96-well plate. For round 2 libraries, 19 colonies per position (i.e., 19 other amino acid residues from wildtype residue), six (6) colonies for GOh1052 variant, and six (6) colonies for negative control (pET28a) were inoculated into a 96-well plate. For round 3 combinatorial library, 84 colonies for variants, six (6) colonies for GOh1052 variant, and six (6) colonies for negative control (pET28a) were inoculated into a 96-well plate (for five (5) plates, 95% coverage) Individual colony was inoculated in 180 L LB medium containing kanamycin (50 g/mL) and cultured overnight at 37 C. 20 L of cultures were transferred to 380 L LB medium containing 50 g/mL kanamycin and grown until an absorbance of 0.5 at 600 nm was reached. Overexpression was induced by adding 0.1 mM IPTG and incubation was continued at 16 C. for 20 hours. Cells were harvested by centrifugation (2,182g for 10 min at 4 C.). The cell pellets were lysed with 250 L lysis buffer (100 mM sodium phosphate buffer, pH 7.0, 0.1% Triton-X, 1 mM copper sulphate) at room temperature for 2 hours at speed 6.5 on titer plate shaker (Barnstead). The lysates were obtained by centrifugation (2,182g for 20 min at 4 C.).

ABTS-HRP* Colorimetric Assay (FIG. 5)

[0269] HTP colorimetric assay conditions: Substrate (1 mM in DMSO), ABTS (2.5 mM in water), HRP (Toyobo, 25 g/mL), and galactose oxidase lysates (25 L) in a final volume of 200 L with final concentration of dimethylsulfoxide (DMSO) at 5% v/v in 100 mM sodium phosphate buffer (pH 7.0). HTP colorimetric assay was carried out using 96-well clear shallow well plates at room temperature and read at 405 nm using a microplate reader (Tecan Infinite M200 Pro) for the following timepoints: every 2 minutes for 1 hour, every 10 minutes for next 2 hours, every 30 minutes for next 5 hours, every 2 hours for next 16 hours for a total of 24 hours.

[0270] Focused secondary alcohol substrate panel colorimetric assay: Identical conditions to HTP colorimetric assay except with galactose oxidase purified protein (20 g/mL) instead of galactose oxidase lysates. Better performing variants against secondary alcohol substrates were selected based on the following formula (maximum absorbanceinitial velocity). *ABTS refers to 2,2-azino-bis(3-ethylbenzothiazoline-6-sulfonic acid), HRP refers to Horseradish peroxidase.

F217 Fitness Landscape (Enantiomeric Bias)

[0271] HTP enzymatic reaction conditions: Substrate 128 (1 mM), HRP (25 g/mL), and galactose oxidase purified protein (100 g/mL) in a final volume of 200 L with final concentration of DMSO at 5% v/v in 100 mM sodium phosphate buffer (pH 7.0). HTP enzymatic reaction was carried out using 96-well deepwell plates with breathable seal at 25 C., 220 rpm. Reaction was stopped at 24 hours via addition of methanol (200 L). The precipitated protein was then removed by centrifugation (2,182g for 20 minutes). 10 L of the reaction mixture was sampled for HPLC-UV analysis.

Thermostability Assay

[0272] Enzyme heat treatment conditions: Purified enzyme (60 L, 400 g/mL) was incubated at 55 C. for 30 minutes in PCR strip tubes using Bio-Rad PTC-200 Thermal Cycler. The heat-treated enzymatic solution was transferred to 1.5 mL tubes and the precipitated protein was removed by centrifugation (20,238g for 5 min at 4 C.). 50 L of the heat-treated enzymatic solution was transferred to a 96 deep well plate for activity assay. Activity assay: Substrate 128 (1 mM), HRP (25 g/mL), and heat-treated galactose oxidase purified protein (100 g/mL) in a final volume of 200 L with final concentration of DMSO at 5% v/v in 100 mM sodium phosphate buffer (pH 7.0). Reactions were carried out in 96 deepwell plates with breathable seal at 25 C., 220 rpm. Reactions were stopped at 24 h via addition of methanol (200 L). The precipitated protein was then removed by centrifugation (2,182g for 20 minutes at 4 C.). 10 L of the reaction mixture was sampled for HPLC-UV analysis. The full experimental materials include: [0273] Suitable reaction vessel (i.e. 2 mL HPLC vials were used) [0274] 5% v/v Dimethyl sulfoxide in 100 mM sodium phosphate buffer (pH=7) as reaction solvent (200 L) [0275] Secondary alcohol substrate (1 mM) [0276] Horseradish peroxidase (25 g/mL) as a co-enzyme to breakdown H.sub.2O.sub.2 that is produced as a by-product of the oxidation reaction [0277] Galactose oxidase protein (40 g/mL) [0278] Sufficient atmospheric oxygen content.

Enzyme Kinetics

[0279] Kinetics colorimetric assay conditions for substrate 128: Substrate 128 (varying concentrations from 2.5 to 30 mM), ABTS (2.5 mM), HRP (25 g/mL) and galactose oxidase purified protein (amount is variant dependent) in a final volume of 200 L with final concentration of DMSO at 5% v/v in 100 mM sodium phosphate buffer (pH 7.0). Kinetic parameters were obtained by the best-fit model of initial velocity against substrate concentrations based on Michaelis-Menten equation using GraphPad Prism 8 (GraphPad Software).

[0280] Amount of galactose oxidase purified protein used: GOh1001b (100 g/mL), GOh1021 (10 g/mL), GOh1036 (10 g/mL), GOh1052 (5 g/mL)

High-Performance Liquid Chromatography (HPLC)

HPLC Validation

[0281] Purified protein reaction conditions: Substrate (1 mM), HRP (25 g/mL), and galactose oxidase purified protein (100 g/mL) in a final volume of 200 L with final concentration of DMSO at 5% v/v in 100 mM sodium phosphate buffer (pH 7.0). Purified protein reaction was carried out in sealed 2 mL HPLC vials at 25 C., 220 rpm. Reaction was stopped at 24 hours via addition of methanol (200 L). The precipitated protein was then removed by centrifugation (20,238g for 1 minute). 10 L of the reaction mixture was sampled for HPLC-UV analysis.

[0282] 40 C. heated activity assay conditions: The conditions are identical to the purified protein reaction conditions described above except that the reactions are conducted at 40 C. temperature for a reaction period of 6 hours.

HPLC Analysis

[0283] HPLC analysis was carried out using Shimadzu Prominence system UFLC or Agilent HPLC 1200 Infinity series paired with CTC Analytics HTS PAL LC Autosampler.

[0284] Mobile phase A: Water; B: Acetonitrile. Column: Phenomenex, Luna 5 m C18(2) 100 , LC Column 1504.6 mm, 1 mL/minute flow rate

[0285] Standards (200 L) of 1 mM substrate and 1 mM product for each compound were prepared with 5% DMSO v/v in 100 mM sodium phosphate buffer (pH 7.0) then diluted with methanol (200 L) before being run with each sample for quantification according to the following formula:

[00001]$\mathrm{HPLC}\mathrm{Yield}\%=\frac{\mathrm{Peak}\mathrm{Integral}\left(\mathrm{Sample}\right)}{\mathrm{Peak}\mathrm{Integral}\left(\mathrm{Standard}\right)}$

HRP-ABTS Colorimetric Assay

HRP-ABTS Colorimetric Assay Screening Data

[0286] Colorimetric activities were assessed calculated from two parameters measured via 405 nm absorbance data gathered by microplate reader (Tecan) according to the following formula:

[00002]$\mathrm{Colorimetric}\mathrm{Activity}=\mathrm{Rate}\mathrm{Maximum}\mathrm{Absorbance}100$ [0287] where, [0288] Colorimetric Activity=measure of enzymatic activity [0289] Rate=initial rate of increase in absorbance in the first 8 minl [0290] Maximum Absorbance=maximum absorbance recorded over the 24 h reaction period

TABLE-US-00001 TABLE 1 Table of galactose oxidase mutations investigated in the present disclosure Position of mutation, numbered based on the protein Mutation sequence of the M3-5 variant of galactose oxidase A24H 24 A24N 24 A26H 26 A26R 26 I28F 28 I28M 28 I28R 28 Q45D 45 Q45E 45 Q45N 45 E49K 49 F65P 65 N69D 69 N69E 69 N69F 69 N69H 69 N69L 69 N69M 69 N69T 69 N69W 69 N69Y 69 W104G 104 W104N 104 S114N 114 S114R 114 T117D 117 T153K 153 T153R 153 G157N 157 S172E 172 S173K 173 S173R 173 T175E 175 T175H 175 T175I 175 T175K 175 V193T 193 P194C 194 A195S 195 A195T 195 A195V 195 A197C 197 A197G 197 A198I 198 T202D 202 T202I 202 T202K 202 T202Q 202 N214R 214 N214S 214 F217A 217 F217C 217 F217D 217 F217E 217 F217G 217 F217H 217 F217I 217 F217K 217 F217L 217 F217M 217 F217N 217 F217P 217 F217Q 217 F217R 217 F217S 217 F217T 217 F217V 217 F217Y 217 E218F 218 E218K 218 E218P 218 E218Y 218 S220T 220 I224W 224 L226Q 226 L226V 226 D239E 239 D239P 239 D239Q 239 R240G 240 F250E 250 F250Y 250 N259T 259 T265S 265 N268W 268 D269N 269 I284S 284 I284Y 284 G294A 294 F313R 313 S314C 314 Y325F 325 N341W 341 A346L 346 K348S 348 Y352T 352 Y352W 352 M353F 353 N356K 356 N356R 356 N356W 356 K389I 389 A401D 401 T429W 429 T447A 447 I485A 485 I485K 485 I485R 485 F487R 487 L537G 537 C538K 538 C538R 538 F546M 546 S559P 559 S576D 576 Y599M 599 Q662D 662 Q662P 662

Exemplary Minimum Fold Changes

[0291] The following exemplary minimum fold changes are to be considered: [0292] For GOh1XXX variant activity (Table 2)1.5-fold more than M3-5 for Substrate 128 (alpha-tetralol) [0293] For GOh2XXX and GOh3XXX variant activity (Tables 3 and 4-1.04-fold more than GOh1052 for substrate 152 (1-phenyl-1-butanol) indicated by Y in Activity (HPLC) column in Table 6. [0294] For GOhXXXX variant activity (Table 2-1.1-fold better than M3-5 for 1 or more substrates in the 64-substrate panel in FIG. 1. [0295] For GOh1XXX protein expression (Table 14)1.06-fold better than M3-5; For GOh1XXX solubility (Table 16)1.13-fold better than M3-5; and thermal stability (Table 12)1.52-fold better than M3-5 [0296] For GOh2XXX and GOh3XXX protein expression (Table 13)1.01-fold better than GOh1052; solubility (Table 15)1.02-fold better than GOh1052; and thermal stability (Table 11)1.01-fold better than GOh1052 [0297] For GOh1XXX enantioselectivity (Table 18minimum reduction of 0.8 R/S ratio from M3-5 experimental value of 20.6 R/S ratio (for substrate 128alpha-tetralol) [0298] For GOh2XXX and GOh3XXX enantioselectivity (Tables 17 and 18-minimum 1.04-fold change reduction in R/S ratio from M3-5 (for substrate 128alpha-tetralol) or from GOh1052 (for substrate 152-1-phenyl-1-butanol) [0299] For ease of comparison, interpretation of reduced enantioselectivity is conveyed as absolute units as a ratio in conversion of (R)- and (S)-enantiomers of the substrate. Higher R/S ratios indicate higher enantioselectivity for (R)-enantiomers while R/S ratios closer to 1 indicate reduced enantioselectivity, with 1 R/S ratio being no enantioselectivity.

TABLE-US-00002 TABLE 2 The colorimetric activity of purified galactose oxidase enzymes activity profile benchmarked against M3-5 backbone. Mutations Activity Fold Mutant No. Substrate (on M3-5) Change M3-5 66, 120, 121, 128, 166 backbone 1.0 GOh1008 66 S314C 19.9 GOh1017 66 F217Q 8.4 GOh1018 66 F217N 3.1 GOh1042 66 F217M 3.0 GOh1039 66 F217G 2.2 GOh1020 66 F217S 2.0 GOh1036 66 F217A 1.3 GOh1006 66 M353F 1.1 GOh1021 120 N268W 3.3 GOh1015 121 F217V 2.1 GOh1017 128 F217Q 132.2 GOh1036 128 F217A 101.9 GOh1039 128 F217G 87.9 GOh1042 128 F217M 73.0 GOh1015 128 F217V 68.7 GOh1018 128 F217N 67.7 GOh1043 128 F217R 40.8 GOh1021 128 N268W 39.8 GOh1030 128 F217I 22.9 GOh1016 128 F217P 20.1 GOh1031 128 F217T 15.0 GOh1020 128 F217S 13.6 GOh1034 128 F217E 5.6 GOh1008 128 S314C 4.9 GOh1009 128 S314K 4.3 GOh1010 128 S314L 3.5 GOh1006 128 M353F 3.1 GOh1023 128 N268F 3.1 GOh1025 128 E218P 3.1 GOh1013 128 L537G 2.5 GOh1024 128 N268K 1.9 GOh1012 128 S314T 1.5 GOh1052 166 F217A, N268W 3643.3 GOh1048 166 F217V, E218P 452.9 GOh1051 166 E218P, L537G 192.2 GOh1045 166 F217P, E218P 188.9 GOh1046 166 F217P, L537G 85.4 GOh1049 166 F217V, L537G 58.3 GOh1055 166 F217G, N268W 47.4

[0300] 39 purified enzymes show improved activity profile benchmarked against M3-5 backbone (Table 2). The experimental conditions used were: Purified protein (10 L, 400 g/mL), 5 L HRP (1 mg/mL), 2.5 mM ABTS, 5% DMSO v/v, 1 mM substrate, 25 C., topped up to 200 L with 100 mM sodium phosphate (pH 7.0) buffer, 24 hours.

TABLE-US-00003 TABLE 3 The colorimetric activity of purified galactose oxidase enzymes activity profile benchmarked against GOh1052 (F217A, N268W from M3-5) backbone for substrate 152. Mutant Mutations Activity Fold No. (on GOh1052) Change GOh1052 backbone 1.0 GOh2015 A197C 22.2 GOh2010 Y352F 18.2 GOh2072 S114R 13.3 GOh2013 Y352T 9.5 GOh2026 K389I 8.2 GOh2011 G294A 8.1 GOh2016 R240G 6.2 GOh2021 T202I 5.9 GOh2025 A346L 4.1 GOh2002 V193T 1.8 GOh2019 T202D 1.8 GOh2020 T202Q 1.8 GOh2018 K348S 1.5 GOh2022 T202K 1.4

[0301] 14 purified enzymes show improved activity profile benchmarked against GOh1052 (F217A, N268W from M3-5) backbone for substrate 152 (Table 3). The experimental conditions used were: Purified protein (10 L, 400 g/mL), 5 L HRP (1 mg/mL), 2.5 mM ABTS, 5% DMSO v/v, 1 mM substrate 152, 25 C., topped up to 200 L with 100 mM sodium phosphate (pH 7.0) buffer, 24 hours.

TABLE-US-00004 TABLE 4 The High Performance Liquid Chromatography (HPLC) Yield Activity of purified galactose oxidase enzymes activity profile benchmarked against GOh1052 (F217A, N268W from M3-5) backbone for substrate 152. Mutant Mutations Activity Fold No. (on GOh1052) Change GOh1052 backbone 1.00 GOh2082 E218F 2.68 GOh2081 A195V 2.04 GOh2044 A24H 2.00 GOh2086 I28F 1.84 GOh2012 A195T 1.80 GOh2027 Y352W 1.76 GOh2045 I28R 1.76 GOh2085 A26R 1.76 GOh2070 D239E 1.68 GOh2084 I224W 1.64 GOh2087 E218Y 1.60 GOh2083 L226Q 1.56 GOh2091 A24N 1.52 GOh2023 P194C 1.36 GOh2092 A26H 1.36 GOh2039 E218K 1.28 GOh2090 F546M 1.28 GOh2001 A195S 1.24 GOh2080 S173K 1.20 GOh2014 N341W 1.16 GOh2076 S173R 1.16 GOh2079 Q662D 1.16 GOh2008 N259T 1.12 GOh2043 I284Y 1.08 GOh2046 I28M 1.08 GOh2047 S576D 1.08 GOh2017 A198I 1.04 GOh2048 I284S 1.04 GOh2055 A197G 1.04 GOh2071 T117D 1.04 GOh2075 Q662P 1.04 GOh2078 S172E 1.04 GOh2089 D239Q 1.04

[0302] 33 purified enzymes show improved activity profile benchmarked against GOh1052 (F217A, N268W from M3-5) backbone for substrate 152 (Table 4). The experimental conditions used were: purified protein (20 L, 400 g/mL), 5 L HRP (1 mg/mL), 5% DMSO v/v, 1 mM substrate 152, 25 C., 220 rpm, topped up to 200 L with 100 mM sodium phosphate (pH 7.0) buffer (in 2 mL HPLC vials), 6 hours.

TABLE-US-00005 TABLE 5 The 40 C. Activity of purified galactose oxidase enzymes activity profile benchmarked against GOh1052 (F217A, N268W from M3-5) backbone for substrate 152. Mutant Mutations HPLC Yield No. (on GOh1052) of Ketone GOh1052 backbone 33% GOh3006 I28R, K389I 72% GOh3008 I28R, T153R, A198I, N341W 64% GOh3038 I28R, A195T, N259T, N341W, K389I 64% GOh3013 I28R, A195T, N259T, K389I 63% GOh3026 I28R, A195T, N259T, T447A 63% GOh3023 I28R, A195T, N341W, K389I 61% GOh2045 I28R 61% GOh2044 A24H 59% GOh2070 D239E 57% GOh3032 I28R, A195S, N259T, N341W 56% GOh3015 I28R, N259T, N341W 52% GOh3018 I28R, A195S, K389I 52% GOh2082 E218F 52% GOh2083 L226Q 52% GOh3003 A198I, N259T 51% GOh2014 N341W 50% GOh2017 A198I 50% GOh2091 A24N 49% GOh2086 I28F 47% GOh2087 E218Y 47% GOh2084 I224W 46% GOh2085 A26R 44% GOh2023 P194C 43% GOh2119 A401D 43% GOh2027 Y352W 41% GOh2055 A197G 41% GOh2089 D239Q 41% GOh2092 A26H 41% GOh2117 T175K 41% GOh2081 A195V 40% GOh2039 E218K 39% GOh2114 T175E 39% GOh2115 T175H 39% GOh2008 N259T 38% GOh2043 I284Y 36% GOh2046 I28M 36% GOh2098 Q45E 36% GOh2116 T175I 36% GOh2071 T117D 35% GOh2090 F546M 35% GOh2111 W104N 35% GOh3002 N341W, Y352T 34% GOh2048 I284S 34% GOh2056 T265S 34% GOh2076 S173R 34%

[0303] 45 purified enzymes show improved heated activity profile benchmarked against GOh1052 (F217A, N268W from M3-5) backbone for substrate 152 (Table 5). The experimental conditions used were: purified protein (20 L, 400 g/mL), 5 L HRP (1 mg/mL), 5% DMSO v/v, 1 mM substrate 152, 40 C., 220 rpm, topped up to 200 L with 100 mM sodium phosphate (pH 7.0) buffer (in 2 mL HPLC vials), 6 hours.

TABLE-US-00006 TABLE 6 The activity, stability, solubility, expression, and enantioselectivity of modified galactose oxidases Mutations on top of Activity Activity Thermal Relaxed Name M3-5 (HPLC) (Colorimetric) Stability Solubility Expression Enantioselectivity GOh1006 M353F Y+ Y Y Y GOh1008 S314C Y+ Y Y GOh1013 L537G Y Y+ Y Y GOh1015 F217V Y Y+ Y GOh1016 F217P Y Y+ Y GOh1017 F217Q Y Y+ Y GOh1018 F217N Y Y+ Y GOh1020 F217S Y Y+ Y Y Y GOh1021 N268W Y Y+ Y GOh1025 E218P Y Y+ Y GOh1030 F217I Y Y GOh1031 F217T Y Y Y GOh1032 F217L Y Y GOh1034 F217E Y+ Y Y GOh1035 F217Y Y Y GOh1036 F217A Y+ Y Y Y GOh1037 F217C Y GOh1038 F217D Y Y GOh1039 F217G Y+ Y Y GOh1040 F217H Y Y GOh1041 F217K Y Y GOh1042 F217M Y+ Y GOh1043 F217R Y+ Y GOh1045 F217P, E218P Y+ GOh1046 F217P, L537G Y+ GOh1047 F217P, E218P, Y+ L537G GOh1048 F217V, E218P Y+ GOh1049 F217V, L537G Y+ GOh1050 F217V, E218P, Y+ L537G GOh1051 E218P, L537G Y+ GOh1052 F217A, N268W Y+ GOh1053 F217A, N268W, Y+ M353F GOh1054 F217A, N268W, Y+ S314C GOh1055 F217G, N268W Y+ GOh1056 F217G, N268W, Y+ M353F GOh2001 F217A, N268W, Y Y+ Y Y A195S GOh2002 F217A, N268W, Y+ V193T GOh2008 F217A, N268W, Y+ Y N259T GOh2010 F217A, N268W, Y+ Y325F GOh2011 F217A, N268W, Y+ G294A GOh2012 F217A, N268W, Y Y+ Y A195T GOh2013 F217A, N268W, Y+ Y352T GOh2014 F217A, N268W, Y+ Y Y Y N341W GOh2015 F217A, N268W, Y+ A197C GOh2016 F217A, N268W, Y+ R240G GOh2017 F217A, N268W, Y+ Y A198I GOh2018 F217A, N268W, Y+ K348S GOh2019 F217A, N268W, Y+ Y T202D GOh2020 F217A, N268W, Y+ Y T202Q GOh2021 F217A, N268W, Y+ Y Y T202I GOh2022 F217A, N268W, Y+ Y T202K GOh2023 F217A, N268W, Y Y+ Y Y P194C GOh2025 F217A, N268W, Y+ Y Y A346L GOh2026 F217A, N268W, Y+ Y Y K389I GOh2027 F217A, N268W, Y Y+ Y Y Y352W GOh2028 F217A, N268W, Y+ Y C538K GOh2029 F217A, N268W, Y+ Y Y C538R GOh2030 F217A, N268W, Y F250E GOh2031 F217A, N268W, Y F250Y GOh2032 F217A, N268W, Y+ Y N356K GOh2033 F217A, N268W, Y+ Y Y N356R GOh2034 F217A, N268W, Y+ Y Y N356W GOh2037 F217A, N268W, Y+ F487R GOh2038 F217A, N268W, Y Y Y T429W GOh2039 F217A, N268W, Y Y+ E218K GOh2041 F217A, N268W, Y Y Y F313R GOh2043 F217A, N268W, Y+ Y I284Y GOh2044 F217A, N268W, Y Y+ Y A24H GOh2045 F217A, N268W, Y Y+ Y Y I28R GOh2046 F217A, N268W, Y+ Y Y I28M GOh2047 F217A, N268W, Y S576D GOh2048 F217A, N268W, Y+ Y Y I284S GOh2050 F217A, N268W, Y Y F65P GOh2053 F217A, N268W, Y T153R GOh2055 F217A, N268W, Y Y A197G GOh2056 F217A, N268W, Y Y T265S GOh2057 F217A, N268W, Y S220T GOh2058 F217A, N268W, Y N214S GOh2061 F217A, N268W, Y I485A GOh2064 F217A, N268W, Y Y N214R GOh2066 F217A, N268W, Y Y D269N GOh2067 F217A, N268W, Y Y I485R GOh2068 F217A, N268W, Y I485K GOh2070 F217A, N268W, Y Y+ Y Y D239E GOh2071 F217A, N268W, Y+ T117D GOh2072 F217A, N268W, Y+ Y Y S114R GOh2073 F217A, N268W, Y Y S559P GOh2074 F217A, N268W, Y S114N GOh2075 F217A, N268W, Y+ Y Q662P GOh2076 F217A, N268W, Y+ S173R GOh2077 F217A, N268W, Y D239P GOh2078 F217A, N268W, Y Y S172E GOh2079 F217A, N268W, Y+ Y Y Q662D GOh2080 F217A, N268W, Y Y+ Y S173K GOh2081 F217A, N268W, Y Y+ Y Y A195V GOh2082 F217A, N268W, Y Y+ Y Y Y E218F GOh2083 F217A, N268W, Y Y Y Y L226Q GOh2084 F217A, N268W, Y Y Y I224W GOh2085 F217A, N268W, Y Y A26R GOh2086 F217A, N268W, Y Y+ Y I28F GOh2087 F217A, N268W, Y Y Y E218Y GOh2088 F217A, N268W, Y L226V GOh2089 F217A, N268W, Y Y D239Q GOh2090 F217A, N268W, Y Y F546M GOh2091 F217A, N268W, Y Y+ Y Y A24N GOh2092 F217A, N268W, Y Y A26H GOh2093 F217A, N268W, Y Y Y599M GOh2094 F217A, N268W, Y Y Y G157N GOh2097 F217A, N268W, Y Y Q45D GOh2098 F217A, N268W, Y Y Y Q45E GOh2099 F217A, N268W, Y Q45N GOh2100 F217A, N268W, Y E49K GOh2101 F217A, N268W, Y Y N69D GOh2102 F217A, N268W, Y Y N69E GOh2103 F217A, N268W, Y N69F GOh2104 F217A, N268W, Y N69H GOh2105 F217A, N268W, Y Y N69L GOh2106 F217A, N268W, Y N69M GOh2107 F217A, N268W, Y N69T GOh2108 F217A, N268W, Y N69W GOh2109 F217A, N268W, Y Y N69Y GOh2110 F217A, N268W, Y Y W104G GOh2111 F217A, N268W, Y Y Y W104N GOh2114 F217A, N268W, Y Y Y T175E GOh2115 F217A, N268W, Y Y Y T175H GOh2116 F217A, N268W, Y Y T175I GOh2117 F217A, N268W, Y Y Y Y T175K GOh2119 F217A, N268W, Y Y Y A401D GOh3001 F217A, N268W, Y Y+ Y A195T, Y352W GOh3002 F217A, N268W, Y Y Y N341W, Y352T GOh3003 F217A, N268W, Y A198I, N259T GOh3004 F217A, N268W, Y A195S, N341W GOh3005 F217A, N268W, Y Y Y T153K, A195S GOh3006 F217A, N268W, Y Y+ Y I28R, K389I GOh3007 F217A, N268W, Y T153R, A195T GOh3008 F217A, N268W, Y Y I28R, T153R, A198I, N341W GOh3009 F217A, N268W, Y Y A195T, N259T, N341W GOh3013 F217A, N268W, Y Y+ Y Y I28R, A195T, N259T, K389I GOh3015 F217A, N268W, Y Y Y Y I28R, N259T, N341W GOh3018 F217A, N268W, Y Y Y I28R, A195S, K389I GOh3019 F217A, N268W, Y Y Y A195T, N341W GOh3023 F217A, N268W, Y Y I28R, A195T, N341W, K389I GOh3026 F217A, N268W, Y Y Y I28R, A195T, N259T, T447A GOh3032 F217A, N268W, Y Y Y Y I28R, A195S, N259T, N341W GOh3038 F217A, N268W, Y Y+ Y I28R, A195T, N259T, N341W, K389I GOh3049 F217A, N268W, Y T153R, N341W

[0304] For Activity (HPLC):

[0305] Interpretation is as follows: [0306] (a) if a Y is obtained for a GOh1XXX modified galactose oxidase tested, then the activity of said modified galactose oxidase is at least 10-fold better than the M3-5 variant for substrate 128 (alpha-tetralol); and [0307] (b) if a Y is obtained for a GOh2XXX or GOh3XXX modified galactose oxidase tested, then the activity of said modified galactose oxidase is at least 1.2-fold better than GOh1052 for substrate 152 (1-phenyl-1-butanol).

[0308] For GOhXXXX variant activitythe minimum fold change for said variant to be considered as having better activity is 1.01-fold better than M3-5 for 1 or more substrates in the 64-substrate panel (indicated in FIG. 1 of the present disclosure).

[0309] For Activity (Colorimetric):

[0310] Interpretation is as follows: [0311] (a) if a Y+ is obtained for any of modified galactose oxidase tested, then said modified galactose oxidase is better than the M3-5 variant for some substrate in the colorimetric substrate panel.

[0312] For Stability (thermal stability), Solubility and Expression (protein expression):

[0313] Interpretation is as follows: [0314] (a) if a Y is obtained for a GOh1XXX modified galactose oxidase tested, then the properties of said modified galactose oxidase is better than the M3-5 variant by 1.01-fold; and (b) if a Y is obtained for a GOh2XXX or GOh3XXX modified galactose oxidase tested, then the properties of said modified galactose oxidase is better than Goh1052 by 1.01-fold.

[0315] For the measure of Relaxed Enantioselectivity

[0316] Interpretation is as follows: [0317] (a) if a Y is obtained for any of the modified galactose oxidase tested, then the enantioselectivity of said modified galactose oxidase is reduced by 1.01-fold compared to that of the M3-5 variant baseline.

[0318] For ease of comparison, interpretation of reduced enantioselectivity is conveyed as absolute units as a ratio in conversion of (R)- and (S)-enantiomers of the substrate. Higher R/S ratios indicate higher enantioselectivity for (R)-enantiomers while R/S ratios closer to 1 indicate reduced enantioselectivity, with 1 R/S ratio being no enantioselectivity.

[0319] For GOh1XXX enantioselectivityminimum reduction of 0.8 R/S ratio from M3-5 experimental value of 20.6 R/S ratio (for substrate 128alpha-tetralol)

[0320] For GOh2XXX and GOh3XXX enantioselectivityminimum reduction of 0.22 R/S ratio from GOh1052 experimental value of 1.67 R/S ratio (for substrate 152-1-phenyl-1-butanol).

Results

Identification of Galactose Oxidase Mutants

[0321] High throughput screening of 6,692 galactose oxidase variants from 352 amino acid positions against substrate 152 have revealed that 31 galactose oxidase variants (0.46%) show improved enzymatic activity (>1.2baseline, Table 7). The oxidation reaction of selected examples of bulky benzylic, unactivated, and heterocyclic aliphatic secondary alcohol substrates to ketones by galactose oxidase mutants are shown in the chemical equation below:

##STR00008##

TABLE-US-00007 TABLE 7 Table showing the Activity Hits from High Throughput Screening of 6,692 galactose oxidase variants Activity vs Variant GOh1052 E218F 2.13 Y599M 1.84 L226Q 1.66 A24H 1.51 A195V 1.49 A26R 1.35 I28A 1.33 L226R 1.33 I224W 1.32 I28M 1.31 D239Q 1.31 K508P 1.31 A401D 1.30 D239E 1.30 I28P 1.29 E218Y 1.29 A26F 1.28 A24N 1.28 I28D 1.28 T542G 1.28 L226V 1.27 I28R 1.26 I28E 1.26 G157N 1.26 A26H 1.25 E218W 1.25 T616V 1.23 I28F 1.23 A24G 1.22 I28H 1.21 A26D 1.20

[0322] 31 Activity Hits were obtained from High Throughput Screening of 6,692 galactose oxidase variants. For the screening, GOh1052 was used as the backbone with 10 mutations (S33P, M93V, F217A, G218E, N268W, W313F, R353M, Q429T, V517A, N558D) from wild-type galactose oxidase from Fusarium graminearum. Screening conditions are described in paragraph [0109] and the Activity calculations are described in paragraph [0128] above.

TABLE-US-00008 TABLE 8 Selected first generation galactose oxidase variant examples based on M3-5 backbone with improved activity for chosen bulky benzylic and unactivated alcohol substrates. Activity (bulky Activity benzylic - (unactivated - substrate substrate Name Mutations 160) 120) Comment M3-5 backbone 1.54 135 Baseline GOh1008 S314C 2.04 264 unactivated activity GOh1021 N268W 5.47 446 unactivated activity GOh1036 F217A 6921 4.50 bulky benzylic activity GOh1052 F217A, 5884 2.87 generalist activity N268W

[0323] As described in paragraph [0110] above, Activity=initial rate*max absorbance*100. Max absorbance=indirect measure of ketone yield based on 405 nm absorbance of a colorimetric probe (ABTS) measuring H.sub.2O.sub.2.

TABLE-US-00009 TABLE 9 Selected second generation variant examples based on GOh1052 (F217A, N268W from M3-5) backbone with improved properties. Up to 10.sup.4-fold activity improvement from baseline M3-5 variant. Activity Activity (bulky (hetero- R/S Residual benzylic- cycle - Ratio.sup.a - Activity.sup.b- substrate substrate substrate substrate Name Mutations 160) 190) 152 152 Comment GOh1052 backbone 5884 4862 1.67 56% baseline GOh2001 A195S 5996 2125 1.05 39% activity, relaxed enantioselectivity GOh2008 N259T 6529 5394 2.00 84% activity GOh2012 A195T 6393 2874 1.73 3% activity GOh2017 A198I 5662 1034 79% thermostable GOh2021 T202I 2376 296 74% thermostable GOh2027 Y352W 2116 1885 1.45 38% ortho-substrate activity GOh2044 A24H 8582 36573 74% activity GOh2045 I28R 6469 9346 79% activity & thermostable GOh2070 D239E 11412 8105 78% activity & thermostable GOh2091 A24N 82% activity & thermostable As described in paragraph [0110] above, Activity = initial rate * max absorbance * 100. Max absorbance = indirect measure of ketone yield based on 405 nm absorbance of a colorimetric probe (ABTS) measuring H.sub.2O.sub.2. .sup.aR/S ratio [(R-isomer substrate 152 converted)/(S-isomer substrate 152 converted)] starting from a 50/50 mixture of each. .sup.bResidual activity = (substrate 152 ketone yield using enzyme heated at 50 C. for 30 min)/(substrate 152 ketone yield using fresh enzyme).

[0324] As described in paragraph [0110] above, Activity=initial rate*max absorbance*100. Max absorbance=indirect measure of ketone yield based on 405 nm absorbance of a colorimetric probe (ABTS) measuring H.sub.2O.sub.2. .sup.aR/S ratio=[(R-isomer substrate 152 converted)/(S-isomer substrate 152 converted)] starting from a 50/50 mixture of each. .sup.bResidual activity=(substrate 152 ketone yield using enzyme heated at 50 C. for 30 min)/(substrate 152 ketone yield using fresh enzyme).

[0325] Selected examples of additional combinatorial third generation variants (incorporating 4 or more synergistic mutations to the M3-5 variant) including galactose oxidase variant GOh3001 (A195T, F217A, N268W, Y352W) showed improved generalist activity and improved acceptance of ortho-substituted substrates (FIG. 3), and galactose oxidase variant GOh3006 (I28R, F217A, N268W, K389I) showed synergistic mutations that combine desirable traits of high activity and thermostability (FIG. 4).

Synthesis of Active Pharmaceutical Ingredient (API) Molecules Using Galactose Oxidase Variants

[0326] Identified beneficial enzyme mutations were applied to synthesize API molecules. The chemical equation below shows two examples of the biocatalytic synthesis of APIs by galactose oxidase variant GOh1052.

##STR00009##

Analysis of the Enzyme Generalist Activity of 12 Galactose Oxidase Mutants

[0327] To determine the enzyme generalist activity of galactose oxidase mutants, purified galactose oxidase enzyme mutants were screened against a panel of 60 secondary alcohols. The screening conditions were: [0328] 10 L purified enzyme (400 g/mL) [0329] 5 L horseradish peroxidase (1 mg/mL) [0330] 1 mM secondary alcohol substrate [0331] 2.5 mM ABTS (colorimetric indicator) [0332] 5% dimethylsulfoxide v/v in 100 mM sodium phosphate buffer (pH=7) [0333] 200 L total reaction volume

[0334] Table 10 below lists 12 galactose oxidase mutants with good enzyme generalist activity compared to the M3-5 variant across the 60-substrate panel. The 60 secondary alcohol substrate panel is shown in FIG. 1. The activity fold improvements have been rounded to the nearest 100.

TABLE-US-00010 TABLE 10 Table of 12 galactose oxidase mutants with good generalist activity across the 60-substrate panel. Averaged Activity Fold vs M3-5 (across 60 Mutant Mutations Substrates) GOh1001b (M3-5) Backbone 1 GOh1036 F217A 900 GOh1052 F217A, N268W 600 GOh2001 F217A, N268W, A195S 600 GOh2008 F217A, N268W, N259T 800 GOh2012 F217A, N268W, A195T 900 GOh2044 F217A, N268W, A24H 1500 GOh2045 F217A, N268W, I28R 1200 GOh2081 F217A, N268W, A195V 1100 GOh2082 F217A, N268W, E218F 2000 GOh3001 F217A, N268W, A195T, Y352W 1000 GOh3013 F217A, N268W, I28R, A195T, 2000 N259T, K389I GOh3038 F217A, N268W, I28R, A195T, 2100 N259T, N341W, K389I

[0335] The activity values for 13 galactose oxidase mutants against 60 substrates are shown in FIG. 5 (colour comparisons are done horizontally per substrate). FIG. 5 shows that the 13 galactose oxidase mutants had generally higher activity values compared to the M3-5 variant. The Averaged Activity Fold was obtained by sequentially: (1) taking the colorimetric activity fold change of each substrate by the selected galactose oxidase variant (e.g., GOh1052) over benchmark M3-5; and (2) taking the average of all the fold changes of a given galactose oxidase variant (e.g. GOh1052) for all 60 substrates in FIG. 5).

Analysis of the Thermostability of Galactose Oxidase Mutants

[0336] The thermostability profile of 55 purified galactose oxidase mutants were compared against the thermostability profile of GOh1052 (F217A, N268W from M3-5) backbone. As shown in FIG. 6, the purified galactose oxidase enzymes were heated at 50 C. or at 55 C. for 30 minutes, and the enzymatic activities of the resulting heat-treated enzymes were measured and compared with the GOh1052 control. Table 11 shows higher residual activity of the heat-treated galactose oxidase mutants compared to GOh1052 control.

TABLE-US-00011 TABLE 11 Table of 55 thermostable mutants compared to GOh1052 (F217A, N268W from M3-5) backbone. Residual Activity Mutant Mutations (50 C. No. (on GOh1052) 30 min) GOh1052 backbone 56% GOh3006 I28R, K389I 90% GOh2008 N259T 84% GOh2091 A24N 82% GOh2104 N69H 82% GOh2045 I28R 79% GOh2105 N69L 79% GOh2017 A198I 79% GOh3015 I28R, N259T, N341W 78% GOh2082 E218F 78% GOh2070 D239E 78% GOh2089 D239Q 76% GOh3003 A198I, N259T 75% GOh2041 F313R 75% GOh2084 I224W 75% GOh2021 T202I 74% GOh2044 A24H 74% GOh2106 N69M 74% GOh3008 I28R, T153R, A198I, N341W 74% GOh2086 I28F 73% GOh2038 T429W 72% GOh2093 Y599M 72% GOh2097 Q45D 72% GOh2100 E49K 72% GOh2046 I28M 70% GOh2087 E218Y 70% GOh2109 N69Y 70% GOh2114 T175E 70% GOh3032 I28R, A195S, N259T, 69% N341W GOh3049 T153R, N431W 69% GOh2083 L226Q 68% GOh2014 N341W 68% GOh2092 A26H 67% GOh2085 A26R 67% GOh3002 N341W, Y352T 66% GOh2055 A197G 66% GOh2115 T175H 66% GOh2116 T175I 66% GOh2043 I284Y 65% GOh2103 N69F 65% GOh2108 N69W 65% GOh3018 I28R, A195S, K389I 65% GOh2064 N214R 63% GOh2048 I284S 62% GOh2107 N69T 62% GOh2117 T175K 62% GOh3038 I28R, A195T, N259T, 62% N341W, K389I GOh2050 F65P 61% GOh2098 Q45E 61% GOh2023 P194C 60% GOh2094 G157N 60% GOh3026 I28R, A195T, N259T, T447A 58% GOh2053 T153R 58% GOh2056 T265S 57% GOh2111 W104N 57% GOh3013 I28R, A195T, N259T, K389I 57%

TABLE-US-00012 TABLE 12 thermostable mutants compared to M3-5 control backbone for substrate 128 Residual Activity Mutant Mutations (55 C. No. (on M3-5) 30 min) M3-5 Backbone 36% GOh1036 F217A 58% GOh1020 F217S 55% GOh1006 M353F 55%

Analysis of the Protein Expression Profile of Galactose Oxidase Mutants

[0337] The protein expression profiles of purified galactose oxidase mutants were compared against the protein expression profile of GOh1052 (F217A, N268W from M3-5) backbone. Tables 13 and 14 show higher protein expression level of purified galactose oxidase mutants compared to the protein expression level of GOh1052 control and M3-5 control, respectively.

TABLE-US-00013 TABLE 13 Table showing improved protein expression profile of 46 purified galactose oxidase mutants versus GOh1052 (F217A, N268W from M3-5) backbone. Mutant Mutations Relative No. (on GOh1052) Expression GOh1052 backbone 1.00 GOh3002 N341W, Y352T 10.09 GOh2119 A401D 6.34 GOh2117 T175K 4.29 GOh2115 T175H 3.46 GOh3004 A195S, N341W 3.36 GOh2102 N69E 2.96 GOh2116 T175I 2.58 GOh2114 T175E 2.47 GOh2101 N69D 2.06 GOh2110 W104G 2.04 GOh2041 F313R 2.00 GOh2105 N69L 1.67 GOh2021 T202I 1.64 GOh2029 C538R 1.62 GOh2109 N69Y 1.58 GOh2022 T202K 1.52 GOh2098 Q45E 1.47 GOh2094 G157N 1.38 GOh2099 Q45N 1.35 GOh2038 T429W 1.34 GOh2028 C538K 1.34 GOh2020 T202Q 1.33 GOh2066 D269N 1.32 GOh3019 A195T, N341W 1.32 GOh2025 A346L 1.31 GOh2034 N356W 1.25 GOh3005 T153K, A195S 1.22 GOh3032 I28R, A195S, N259T, N341W 1.21 GOh2111 W104N 1.19 GOh2067 I485R 1.17 GOh3015 I28R, N259T, N341W 1.17 GOh2033 N356R 1.17 GOh2081 A195V 1.15 GOh2078 S172E 1.14 GOh2026 K389I 1.14 GOh2070 D239E 1.11 GOh2072 S114R 1.11 GOh2093 Y599M 1.08 GOh2079 Q662D 1.05 GOh2023 P194C 1.05 GOh2073 S559P 1.03 GOh2083 L226Q 1.03 GOh2082 E218F 1.03 GOh2027 Y352W 1.02 GOh2014 N341W 1.01 GOh3009 A195T, N259T, N341W 1.01

TABLE-US-00014 TABLE 14 Table showing improved protein expression profile of 10 purified galactose oxidase mutants versus M3-5 control backbone. Mutant Mutations Relative No. (on M3-5) Expression M3-5 Backbone 1.00 GOh1006 M353F 1.73 GOh1008 S314C 1.51 GOh1013 L537G 1.64 GOh1017 F217Q 1.06 GOh1018 F217N 1.16 GOh1020 F217S 1.41 GOh1025 E218P 1.36 GOh1035 F217Y 1.10 GOh1039 F217G 1.25 GOh1040 F217H 1.19

Analysis of the Protein Solubility of Galactose Oxidase Mutants

[0338] The protein solubilities of purified galactose oxidase mutants were compared against the protein solubility of GOh1052 (F217A, N268W from M3-5) backbone. Tables 15 and 16 show increased protein solubility of purified galactose oxidase mutants compared to the protein solubility of GOh1052 control, and M3-5 control, respectively.

TABLE-US-00015 TABLE 15 Table showing increased protein solubility of 58 purified galactose oxidase mutants versus GOh1052 (F217A, N268W from M3-5) backbone. Mutant Mutations Soluble/Insoluble No. (on GOh1052) Ratio GOh1052 backbone 0.44 GOh3023 I28R, A195T, N341W, K389I 2.01 GOh2082 E218F 1.24 GOh2056 T265S 1.12 GOh2079 Q662D 1.03 GOh3018 I28R, A195S, K389I 0.99 GOh3013 I28R, A195T, N259T, K389I 0.99 GOh2041 F313R 0.95 GOh2084 I224W 0.84 GOh2081 A195V 0.80 GOh2068 I485K 0.79 GOh2033 N356R 0.76 GOh2119 A401D 0.74 GOh2080 S173K 0.74 GOh2047 S576D 0.73 GOh2038 T429W 0.72 GOh2075 Q662P 0.71 GOh2067 I485R 0.71 GOh3032 I28R, A195S, N259T, N341W 0.71 GOh2083 L226Q 0.70 GOh2073 S559P 0.68 GOh2074 S114N 0.67 GOh2048 I284S 0.66 GOh2089 D239Q 0.65 GOh2030 F250E 0.64 GOh3019 A195T, N341W 0.64 GOh2046 I28M 0.63 GOh3001 A195T, Y352W 0.62 GOh3015 I28R, N259T, N341W 0.61 GOh2088 L226V 0.61 GOh3026 I28R, A195T, N259T, T447A 0.61 GOh3005 T153K, A195S 0.60 GOh2050 F65P 0.60 GOh2045 I28R 0.59 GOh2091 A24N 0.58 GOh2098 Q45E 0.58 GOh2101 N69D 0.57 GOh2064 N214R 0.57 GOh2094 G157N 0.55 GOh2032 N356K 0.53 GOh2058 N214S 0.53 GOh2087 E218Y 0.52 GOh2061 I485A 0.52 GOh2102 N69E 0.51 GOh2078 S172E 0.51 GOh2031 F250Y 0.50 GOh2012 A195T 0.50 GOh2117 T175K 0.49 GOh2097 Q45D 0.48 GOh2072 S114R 0.47 GOh2055 A197G 0.47 GOh2034 N356W 0.46 GOh2029 C538R 0.46 GOh2090 F546M 0.46 GOh2077 D239P 0.46 GOh2066 D269N 0.45 GOh2026 K389I 0.45 GOh2057 S220T 0.45 GOh2001 A195S 0.45

TABLE-US-00016 TABLE 16 Table showing increased protein solubility of 11 purified galactose oxidase mutants versus M3-5 control backbone. Mutations Soluble/Insoluble Mutant No. (on M3-5) Ratio M3-5 Backbone 0.58 GOh1038 F217D 0.97 GOh1013 L537G 0.94 GOh1008 S314C 0.78 GOh1032 F217L 0.78 GOh1031 F217T 0.78 GOh1006 M353F 0.77 GOh1036 F217A 0.77 GOh1021 N268W 0.76 GOh1041 F217K 0.73 GOh1035 F217Y 0.69 GOh1034 F217E 0.66

Analysis of Relaxed Enantioselectivity Profile of Galactose Oxidase Mutants

TABLE-US-00017 TABLE 17 Table showing relaxed enantioselectivity profile of five purified enzymes (for substrate 152) versus GOh1052 (F217A, N268W from M3-5) backbone. Mutant Mutations No. (on GOh1052) R/S Ratio GOh1052 backbone 1.67 GOh2001 A195S 1.05 GOh2025 A346L 1.25 GOh2019 T202D 1.27 GOh2014 N341W 1.35 GOh2027 Y352W 1.45

TABLE-US-00018 TABLE 18 Table showing relaxed enantioselectivity profile of 15 purified enzymes at F217 position (for substrate 128) versus M3-5 backbone. Mutant Mutations No. (on M3-5) R/S Ratio M3-5 Backbone 20.6 GOh1036 F217A 1.6 GOh1039 F217G 3.4 GOh1016 F217P 4.1 GOh1041 F217K 4.1 GOh1042 F217M 4.7 GOh1015 F217V 4.9 GOh1038 F217D 6.0 GOh1032 F217L 6.4 GOh1030 F217I 6.7 GOh1043 F217R 6.9 GOh1020 F217S 7.0 GOh1031 F217T 7.1 GOh1037 F217C 8.6 GOh1034 F217E 13.5 GOh1040 F217H 19.8

[0339] The fold change ratios can be calculated as the benchmark R/S ratio divided by the mutant R/S ratio, which gives the fold decrease in enantio selectivity. For example, for GOh1036 benchmarked to M3-5, calculation is: 20.6 (M3-5 R/S ratio)/1.6 (GOh1036 R/S ratio) A v12.875 (round up to 12.9).

Construction of the Combinatorial Library Targeting Generalist Activity and Stability of Galactose Oxidase Mutants.

[0340] Combinatorial library targeting generalist activity and stability was constructed from the following eight mutations (six amino acid mutation positions) [0341] Generalist Activity: A195S, A195T, N259T, K389I [0342] Stability: I28R, T153R, T153K, N341W

[0343] Purified galactose oxidase proteins from the combinatorial library have been found to surpass single mutants in the characteristics shown in Table 19.

TABLE-US-00019 TABLE 19 Single Mutant Fold vs Combinatorial Fold vs Charac- (mutations on GOh1052 (mutations on GOh1052 teristic GOh1052) backbone GOh1052) backbone 40 C. GOh2045 1.85 GOh3006 (I28R, 2.18 Activity (I28R) K389I) Thermal GOh2008 1.50 GOh3006 (I28R, 1.61 Stability (N259T) K389I) Protein GOh2041 2.00 GOh3002 10.09 Expression (F313R) (N341W, Y352T) Solubility GOh2082 2.82 GOh3023 (I28R, 4.57 (E218F) A195T, N341W, K389I)

[0344] Synergistic mutations I28R and K389I (GOh3006) have been found to combine the desirable traits of both generalist activity and thermostability.

[0345] The present disclosure describes for the first time, galactose oxidase variants that convey superior enhancement in enzymatic activity towards bulky secondary alcohols and unactivated secondary alcohols.

[0346] The galactose oxidase variants of the present disclosure have the following advantages: [0347] 1. The galactose oxidase variants disclosed herein are capable of oxidising secondary alcohols and oxidising unactivated secondary alcohols. [0348] 2. The galactose oxidase variants disclosed herein has reduced enantioselectivity compared to modified galactose oxidase known in the art. [0349] 3. The galactose oxidase variants disclosed herein has improved enzyme solubility. [0350] 4. The galactose oxidase variants disclosed herein has improved protein expression. [0351] 5. The galactose oxidase variants disclosed herein has improved enzyme thermal stability. [0352] 6. The galactose oxidase variants disclosed herein possess overall improvement in enzyme properties such as activity, selectivity, expression, thermal stability and/or solubility. [0353] 7. The galactose oxidase variants disclosed herein can be used as a part of/all of the process for the manufacturing of APIs. [0354] 8. The galactose oxidase variants disclosed herein are useful in applications requiring the use of biocatalysts, e.g., bioremediation, cleaning, food production.

TABLE-US-00020 SEQUENCELISTING SEQID NO SequenceName Sequence 1 GO01=Wildtype atgggcagcagccatcatcatcatcatcacagcagcggcctggtgccgcgcggca galactoseoxidase gccatatgggtaccgcttctgctccaattggttctgctatttccagaaacaattg fromFusarium ggctgttacttgtgattctgctcaatctggtaatgaatgtaacaaggctattgat graminearum; ggtaacaaggatactttttggcatactttctacggtgctaacggagatccaaaac hasadditional cacctcacacttacactatcgatatgaagactactcaaaacgttaatggtttgtc His-tag tatgttgcctagacaagatggtaaccaaaatggttggattggtagacatgaagtt attheC-terminal tacttgtcttctgatggtactaattggggttctcctgttgcttccggttcttggt ttgctgattctactactaaatactctaacttcgagactagaccagctagatatgt tagattggttgctgttactgaagctaatggtcaaccttggacttctattgctgag attaacgtttttcaggcttcttcttacactgctccacaacctggtttgggtagat ggggtccaactattgatttgccaattgttcctgctgctgctgctattgagcctac ttctggtagagttttgatgtggtcttcttatagaaatgatgcttttggtggttct ccaggtggtattactttgacttcttcttgggacccatctactggtattgtttctg atagaactgttactgttactaagcatgatatgttctgtccaggtatttctatgga tggtaatggtcaaattgttgttactggtggtaacgatgctaagaaaacttctttg tacgattcttcttctgattcttggattccaggtcctgatatgcaagttgctagag gttatcaatcttctgctactatgtctgatggtagagtttttactattggtggttc ttggtctggtggtgttttcgaaaagaacggagaggtttactctccatcttctaag acttggacttctttgccaaatgctaaagttaaccctatgttgactgctgataagc aaggtttgtatagatctgataatcacgcttggttgtttggttggaagaaaggttc tgttttccaagctggtccttctactgctatgaactggtactatacttctggttct ggagatgttaagtctgctggtaaaagacaatctaatagaggtgttgctccagatg ctatgtgtggtaacgctgttatgtacgatgctgttaagggtaaaattttgacttt cggtggttctcctgattatcaagattctgatgctactactaacgctcatatcatc actttgggtgaaccaggtacttctcctaatactgtttttgcttctaacggtttgt actttgctagaactttccacacttctgttgttttgccagatggttctactttcat tactggtggtcaaagaagaggtattccttttgaggattctactccagttttcact cctgaaatctacgttccagagcaagatactttctacaagcaaaaccctaattcta tcgttagagtttaccattctatttctttgttgttgccagatggtagagttttcaa cggtggtggtggtttgtgtggagattgtactactaaccacttcgatgctcaaatt ttcactccaaactacttgtacaactctaacggtaacttggctactagacctaaga tcactagaacttctactcaatctgttaaggttggtggtagaatcactatttctac tgattcttctatcactaaggcttctttgatcagatatggtactgctactcacact gttaatactgatcaaagaagaatcccattgactttgactaacaatggtggtaact cttactcttttcaagttccatctgattctggtgttgctttgcctggttattggat gttgttcgttatgaactctgctggtgttccttctgttgcttctactattagagtt actcaagcggccgcactcgagcaccaccaccaccaccactga 2 GO01=Wildtype MGSSHHHHHHSSGLVPRGSHMGTASAPIGSAISRNNWAVTCDSAQSGNECNKAID galactoseoxidase GNKDTFWHTFYGANGDPKPPHTYTIDMKTTQNVNGLSMLPRQDGNQNGWIGRHEV fromFusarium YLSSDGTNWGSPVASGSWFADSTTKYSNFETRPARYVRLVAVTEANGQPWTSIAE graminearum; INVFQASSYTAPQPGLGRWGPTIDLPIVPAAAAIEPTSGRVLMWSSYRNDAFGGS sameprotein PGGITLTSSWDPSTGIVSDRTVTVTKHDMFCPGISMDGNGQIVVTGGNDAKKTSL sequenceas YDSSSDSWIPGPDMQVARGYQSSATMSDGRVFTIGGSWSGGVFEKNGEVYSPSSK GO01bbuthas TWTSLPNAKVNPMLTADKQGLYRSDNHAWLFGWKKGSVFQAGPSTAMNWYYTSGS additionalHis-tag GDVKSAGKRQSNRGVAPDAMCGNAVMYDAVKGKILTFGGSPDYQDSDATTNAHII attheC-terminal TLGEPGTSPNTVFASNGLYFARTFHTSVVLPDGSTFITGGQRRGIPFEDSTPVFT PEIYVPEQDTFYKQNPNSIVRVYHSISLLLPDGRVFNGGGGLCGDCTTNHFDAQI FTPNYLYNSNGNLATRPKITRTSTQSVKVGGRITISTDSSITKASLIRYGTATHT VNTDQRRIPLTLTNNGGNSYSFQVPSDSGVALPGYWMLFVMNSAGVPSVASTIRV TQAAALEHHHHHH 3 GO01b=E.coli atgggcagcagccatcatcatcatcatcacagcagcggcctggtgccgcgcggca optimizedversion gccatatgggtaccgcctctgcccctatcggctcagccatctcacgcaataactg ofGO01;noC- ggccgtaacgtgcgacagcgcgcagagcggcaacgagtgcaataaagccatcgac terminalHis-tag ggcaataaagacaccttctggcacacgttttatggcgcaaatggcgacccgaagc caccgcatacctataccattgacatgaaaaccacccagaatgtgaacgggctgtc catgctgccgcgccaggacggcaatcagaacggatggatcggccgtcacgaggta tatttaagctccgacggcaccaactggggatccccggtcgcgtcgggcagctggt tcgccgacagcaccaccaagtattccaattttgaaacccgtcctgcacgctacgt gcgcttagtggccgtgacagaggcgaacggccagccatggacctcaatcgccgaa atcaatgtattccaagccagctcctataccgcgccgcagccaggacttgggcgtt ggggcccgaccatcgacctgcctatcgtacccgcagccgcggcgattgaaccaac gtcaggccgcgtactgatgtggagcagctaccgtaacgacgcgttcggcggcagc ccgggcggcatcactctgacgtcgagttgggatccatccacgggcatcgtctccg accgcaccgtgaccgtcacgaaacacgacatgttttgcccggggatcagcatgga cggcaacggccagatcgtcgtcacgggcggcaatgacgccaagaagacgagcctc tatgacagtagcagcgacagttggatcccggggccggacatgcaggtggcacgcg ggtaccagtccagcgcgaccatgtcagacggccgtgtctttacaatcggcggctc atggagtggcggagtgtttgagaagaatggcgaagtctatagcccctcatccaaa acgtggacgtcacttccgaacgcgaaggtgaatcccatgttaaccgccgacaaac agggcctgtaccgcagcgacaaccatgcgtggctgttcggctggaagaaggggag cgtctttcaggcgggcccgtcgaccgcaatgaattggtattacacgtcaggaagc ggggacgtgaaatcagccggcaagcgccagtcgaaccgcggcgtggcgccggacg caatgtgcggcaatgccgtgatgtatgacgcggtcaaaggcaagatcctgacatt tggcgggagtccggactaccaggacagtgacgcgacaaccaatgcccacattatt acccttggggagccggggacgagcccgaacacggtcttcgcgtccaatggcctct atttcgcgcgtacctttcatacgtcggtggtcctgccggacggatcaacctttat caccggcggacagcgccgtggcatccccttcgaagactcgacccccgtctttaca ccggagatttatgtgccggaacaggacacgttttataaacagaatccgaactcga ttgtacgcgtgtatcactccatcagccttcttctcccggacggacgtgtctttaa tggcggaggaggactgtgcggggactgcacgaccaatcattttgacgcgcagatc tttaccccgaattatctgtataattcaaatgggaatctcgcgacccgtccgaaaa ttacccgtacatcaacccagtccgtcaaagtgggcggccgcattacgatcagtac cgacagcagcattaccaaagcgtcactgattcgttacggcaccgcaacccataca gtcaacacggaccagcgccgtattccgttaaccctgaccaataacggtggcaatt cgtatagcttccaggtaccgtcggactcgggcgtggcgctgccaggatactggat gctgtttgtgatgaatagcgcgggcgtcccgagcgtagcgagcacgatccgtgtg acccaggccgcagcttgataa 4 GO01b=E.coli MGSSHHHHHHSSGLVPRGSHMGTASAPIGSAISRNNWAVTCDSAQSGNECNKAID optimizedversion GNKDTFWHTFYGANGDPKPPHTYTIDMKTTQNVNGLSMLPRQDGNQNGWIGRHEV ofGO01;noC- YLSSDGTNWGSPVASGSWFADSTTKYSNFETRPARYVRLVAVTEANGQPWTSIAE terminalHis-tag INVFQASSYTAPQPGLGRWGPTIDLPIVPAAAAIEPTSGRVLMWSSYRNDAFGGS PGGITLTSSWDPSTGIVSDRTVTVTKHDMFCPGISMDGNGQIVVTGGNDAKKTSL YDSSSDSWIPGPDMQVARGYQSSATMSDGRVFTIGGSWSGGVFEKNGEVYSPSSK TWTSLPNAKVNPMLTADKQGLYRSDNHAWLFGWKKGSVFQAGPSTAMNWYYTSGS GDVKSAGKRQSNRGVAPDAMCGNAVMYDAVKGKILTFGGSPDYQDSDATTNAHII TLGEPGTSPNTVFASNGLYFARTFHTSVVLPDGSTFITGGQRRGIPFEDSTPVFT PEIYVPEQDTFYKQNPNSIVRVYHSISLLLPDGRVFNGGGGLCGDCTTNHFDAQI FTPNYLYNSNGNLATRPKITRTSTQSVKVGGRITISTDSSITKASLIRYGTATHT VNTDQRRIPLTLTNNGGNSYSFQVPSDSGVALPGYWMLFVMNSAGVPSVASTIRV TQAAA 5 GOh1001b= atgggcagcagccatcatcatcatcatcacagcagcggcctggtgccgcgcggca GO01b+8 gccatatgggtaccgcctctgcccctatcggctcagccatcccgcgcaataactg mutationsfrom ggccgtaacgtgcgacagcgcgcagagcggcaacgagtgcaataaagccatcgac Turner's ggcaataaagacaccttctggcacacgttttatggcgcaaatggcgacccgaagc ChemBiochem caccgcatacctataccattgacatgaaaaccacccagaatgtgaacgggctgtc 2008paperto cgtgctgccgcgccaggacggcaatcagaacggatggatcggccgtcacgaggta changesubstrate tatttaagctccgacggcaccaactggggatccccggtcgcgtcgggcagctggt specificitymore tcgccgacagcaccaccaagtattccaattttgaaacccgtcctgcacgctacgt towards gcgcttagtggccgtgacagaggcgaacggccagccatggacctcaatcgccgaa secondary atcaatgtattccaagccagctcctataccgcgccgcagccaggacttgggcgtt alcohols; ggggcccgaccatcgacctgcctatcgtacccgcagccgcggcgattgaaccaac backbonefor gtcaggccgcgtactgatgtggagcagctaccgtaacgacgcgttcgaaggcagc Round1;termed ccgggcggcatcactctgacgtcgagttgggatccatccacgggcatcgtctccg asM3-5variant accgcaccgtgaccgtcacgaaacacgacatgttttgcccggggatcagcatgga forcomparisonto cggcaacggccagatcgtcgtcacgggcggcaatgacgccaagaagacgagcctc Turner'spaper tatgacagtagcagcgacagttggatcccggggccggacatgcaggtggcacgcg ggtaccagtccagcgcgaccatgtcagacggccgtgtctttacaatcggcggctc atttagtggcggagtgtttgagaagaatggcgaagtctatagcccctcatccaaa acgtggacgtcacttccgaacgcgaaggtgaatcccatgttaaccgccgacaaac agggcctgtacatgagcgacaaccatgcgtggctgttcggctggaagaaggggag cgtctttcaggcgggcccgtcgaccgcaatgaattggtattacacgtcaggaagc ggggacgtgaaatcagccggcaagcgccagtcgaaccgcggcgtggcgccggacg caatgtgcggcaatgccgtgatgtatgacgcggtcaaaggcaagatcctgacatt tggcgggagtccggactacaccgacagtgacgcgacaaccaatgcccacattatt acccttggggagccggggacgagcccgaacacggtcttcgcgtccaatggcctct atttcgcgcgtacctttcatacgtcggtggtcctgccggacggatcaacctttat caccggcggacagcgccgtggcatccccttcgaagactcgacccccgtctttaca ccggagatttatgtgccggaacaggacacgttttataaacagaatccgaactcga ttgtacgcgcgtatcactccatcagccttcttctcccggacggacgtgtctttaa tggcggaggaggactgtgcggggactgcacgaccaatcattttgacgcgcagatc tttaccccgaattatctgtatgattcaaatgggaatctcgcgacccgtccgaaaa ttacccgtacatcaacccagtccgtcaaagtgggcggccgcattacgatcagtac cgacagcagcattaccaaagcgtcactgattcgttacggcaccgcaacccataca gtcaacacggaccagcgccgtattccgttaaccctgaccaataacggtggcaatt cgtatagcttccaggtaccgtcggactcgggcgtggcgctgccaggatactggat gctgtttgtgatgaatagcgcgggcgtcccgagcgtagcgagcacgatccgtgtg acccaggccgcagcttgataa 6 GOh1001b= MGSSHHHHHHSSGLVPRGSHMGTASAPIGSAIPRNNWAVTCDSAQSGNECNKAID GO01b+8 GNKDTFWHTFYGANGDPKPPHTYTIDMKTTQNVNGLSVLPRQDGNQNGWIGRHEV GOh1001b= YLSSDGTNWGSPVASGSWFADSTTKYSNFETRPARYVRLVAVTEANGQPWTSIAE GO01b+8 INVFQASSYTAPQPGLGRWGITLTSSWDPSTGIVSDRTVTVTKHDMFCPGISMDG mutationsfrom NGQIVVTGGNDAKKTSLYDSSSDSWIPGPDMQVARGYQSSATMSDGRVFTIGGSF Turner's SGGVFEKNGEVYSPSSKTWTSLPNAKVNPMLTADKQGLYMSDNHAWLFGWKKGSV ChemBiochem FQAGPSTAMNWYYTSGSGDVKSAGKRQSNRGVAPDAMCGNAVMYDAVKGKILTFG 2008paperto GSPDYTDSDATTNAHIITLGEPGTSPNTVFASNGLYFARTFHTSVVLPDGSTFIT changesubstrate GGQRRGIPFEDSTPVFTPEIYVPEQDTFYKQNPNSIVRAYHSISLLLPDGRVFNG specificitymore GGGLCGDCTTNHFDAQIFTPNYLYDSNGNLATRPKITRTSTQSVKVGGRITISTD towards SSITKASLIRYGTATHTVNTDQRRIPLTLTNNGGNSYSFQVPSDSGVALPGYWML secondary FVMNSAGVPSVASTIRVTQAAA alcohols; backbonefor Round1;termed asM3-5variant forcomparisonto Turner'spaper 7 GOh1006 atgggcagcagccatcatcatcatcatcacagcagcggcctggtgccgcgcggca gccatatgggtaccgcctctgcccctatcggctcagccatcccgcgcaataactg ggccgtaacgtgcgacagcgcgcagagcggcaacgagtgcaataaagccatcgac ggcaataaagacaccttctggcacacgttttatggcgcaaatggcgacccgaagc caccgcatacctataccattgacatgaaaaccacccagaatgtgaacgggctgtc cgtgctgccgcgccaggacggcaatcagaacggatggatcggccgtcacgaggta tatttaagctccgacggcaccaactggggatccccggtcgcgtcgggcagctggt tcgccgacagcaccaccaagtattccaattttgaaacccgtcctgcacgctacgt gcgcttagtggccgtgacagaggcgaacggccagccatggacctcaatcgccgaa atcaatgtattccaagccagctcctataccgcgccgcagccaggacttgggcgtt ggggcccgaccatcgacctgcctatcgtacccgcagccgcggcgattgaaccaac gtcaggccgcgtactgatgtggagcagctaccgtaacgacgcgttcgaaggcagc ccgggcggcatcactctgacgtcgagttgggatccatccacgggcatcgtctccg accgcaccgtgaccgtcacgaaacacgacatgttttgcccggggatcagcatgga cggcaacggccagatcgtcgtcacgggcggcaatgacgccaagaagacgagcctc tatgacagtagcagcgacagttggatcccggggccggacatgcaggtggcacgcg ggtaccagtccagcgcgaccatgtcagacggccgtgtctttacaatcggcggctc atttagtggcggagtgtttgagaagaatggcgaagtctatagcccctcatccaaa acgtggacgtcacttccgaacgcgaaggtgaatcccatgttaaccgccgacaaac agggcctgtactttagcgacaaccatgcgtggctgttcggctggaagaaggggag cgtctttcaggcgggcccgtcgaccgcaatgaattggtattacacgtcaggaagc ggggacgtgaaatcagccggcaagcgccagtcgaaccgcggcgtggcgccggacg caatgtgcggcaatgccgtgatgtatgacgcggtcaaaggcaagatcctgacatt tggcgggagtccggactacaccgacagtgacgcgacaaccaatgcccacattatt acccttggggagccggggacgagcccgaacacggtcttcgcgtccaatggcctct atttcgcgcgtacctttcatacgtcggtggtcctgccggacggatcaacctttat caccggcggacagcgccgtggcatccccttcgaagactcgacccccgtctttaca ccggagatttatgtgccggaacaggacacgttttataaacagaatccgaactcga ttgtacgcgcgtatcactccatcagccttcttctcccggacggacgtgtctttaa tggcggaggaggactgtgcggggactgcacgaccaatcattttgacgcgcagatc tttaccccgaattatctgtatgattcaaatgggaatctcgcgacccgtccgaaaa ttacccgtacatcaacccagtccgtcaaagtgggcggccgcattacgatcagtac cgacagcagcattaccaaagcgtcactgattcgttacggcaccgcaacccataca gtcaacacggaccagcgccgtattccgttaaccctgaccaataacggtggcaatt cgtatagcttccaggtaccgtcggactcgggcgtggcgctgccaggatactggat gctgtttgtgatgaatagcgcgggcgtcccgagcgtagcgagcacgatccgtgtg acccaggccgcagcttgataa 8 GOh1006 MGSSHHHHHHSSGLVPRGSHMGTASAPIGSAIPRNNWAVTCDSAQSGNECNKAID GNKDTFWHTFYGANGDPKPPHTYTIDMKTTQNVNGLSVLPRQDGNQNGWIGRHEV YLSSDGTNWGSPVASGSWFADSTTKYSNFETRPARYVRLVAVTEANGQPWTSIAE INVFQASSYTAPQPGLGRWGPTIDLPIVPAAAAIEPTSGRVLMWSSYRNDAFEGS PGGITLTSSWDPSTGIVSDRTVTVTKHDMFCPGISMDGNGQIVVTGGNDAKKTSL YDSSSDSWIPGPDMQVARGYQSSATMSDGRVFTIGGSFSGGVFEKNGEVYSPSSK TWTSLPNAKVNPMLTADKQGLYFSDNHAWLFGWKKGSVFQAGPSTAMNWYYTSGS GDVKSAGKRQSNRGVAPDAMCGNAVMYDAVKGKILTFGGSPDYTDSDATTNAHII TLGEPGTSPNTVFASNGLYFARTFHTSVVLPDGSTFITGGQRRGIPFEDSTPVFT PEIYVPEQDTFYKQNPNSIVRAYHSISLLLPDGRVFNGGGGLCGDCTTNHFDAQI FTPNYLYDSNGNLATRPKITRTSTQSVKVGGRITISTDSSITKASLIRYGTATHT VNTDQRRIPLTLTNNGGNSYSFQVPSDSGVALPGYWMLFVMNSAGVPSVASTIRV TQAAA 9 GOh1008 atgggcagcagccatcatcatcatcatcacagcagcggcctggtgccgcgcggca gccatatgggtaccgcctctgcccctatcggctcagccatcccgcgcaataactg ggccgtaacgtgcgacagcgcgcagagcggcaacgagtgcaataaagccatcgac ggcaataaagacaccttctggcacacgttttatggcgcaaatggcgacccgaagc caccgcatacctataccattgacatgaaaaccacccagaatgtgaacgggctgtc cgtgctgccgcgccaggacggcaatcagaacggatggatcggccgtcacgaggta tatttaagctccgacggcaccaactggggatccccggtcgcgtcgggcagctggt tcgccgacagcaccaccaagtattccaattttgaaacccgtcctgcacgctacgt gcgcttagtggccgtgacagaggcgaacggccagccatggacctcaatcgccgaa atcaatgtattccaagccagctcctataccgcgccgcagccaggacttgggcgtt ggggcccgaccatcgacctgcctatcgtacccgcagccgcggcgattgaaccaac gtcaggccgcgtactgatgtggagcagctaccgtaacgacgcgttcgaaggcagc ccgggcggcatcactctgacgtcgagttgggatccatccacgggcatcgtctccg accgcaccgtgaccgtcacgaaacacgacatgttttgcccggggatcagcatgga cggcaacggccagatcgtcgtcacgggcggcaatgacgccaagaagacgagcctc tatgacagtagcagcgacagttggatcccggggccggacatgcaggtggcacgcg ggtaccagtccagcgcgaccatgtcagacggccgtgtctttacaatcggcggctc attttgtggcggagtgtttgagaagaatggcgaagtctatagcccctcatccaaa acgtggacgtcacttccgaacgcgaaggtgaatcccatgttaaccgccgacaaac agggcctgtacatgagcgacaaccatgcgtggctgttcggctggaagaaggggag cgtctttcaggcgggcccgtcgaccgcaatgaattggtattacacgtcaggaagc ggggacgtgaaatcagccggcaagcgccagtcgaaccgcggcgtggcgccggacg caatgtgcggcaatgccgtgatgtatgacgcggtcaaaggcaagatcctgacatt tggcgggagtccggactacaccgacagtgacgcgacaaccaatgcccacattatt acccttggggagccggggacgagcccgaacacggtcttcgcgtccaatggcctct atttcgcgcgtacctttcatacgtcggtggtcctgccggacggatcaacctttat caccggcggacagcgccgtggcatccccttcgaagactcgacccccgtctttaca ccggagatttatgtgccggaacaggacacgttttataaacagaatccgaactcga ttgtacgcgcgtatcactccatcagccttcttctcccggacggacgtgtctttaa tggcggaggaggactgtgcggggactgcacgaccaatcattttgacgcgcagatc tttaccccgaattatctgtatgattcaaatgggaatctcgcgacccgtccgaaaa ttacccgtacatcaacccagtccgtcaaagtgggcggccgcattacgatcagtac cgacagcagcattaccaaagcgtcactgattcgttacggcaccgcaacccataca gtcaacacggaccagcgccgtattccgttaaccctgaccaataacggtggcaatt cgtatagcttccaggtaccgtcggactcgggcgtggcgctgccaggatactggat gctgtttgtgatgaatagcgcgggcgtcccgagcgtagcgagcacgatccgtgtg acccaggccgcagcttgataa 10 GOh1008 MGSSHHHHHHSSGLVPRGSHMGTASAPIGSAIPRNNWAVTCDSAQSGNECNKAID GNKDTFWHTFYGANGDPKPPHTYTIDMKTTQNVNGLSVLPRQDGNQNGWIGRHEV YLSSDGTNWGSPVASGSWFADSTTKYSNFETRPARYVRLVAVTEANGQPWTSIAE INVFQASSYTAPQPGLGRWGPTIDLPIVPAAAAIEPTSGRVLMWSSYRNDAFEGS PGGITLTSSWDPSTGIVSDRTVTVTKHDMFCPGISMDGNGQIVVTGGNDAKKTSL YDSSSDSWIPGPDMQVARGYQSSATMSDGRVFTIGGSFCGGVFEKNGEVYSPSSK TWTSLPNAKVNPMLTADKQGLYMSDNHAWLFGWKKGSVFQAGPSTAMNWYYTSGS GDVKSAGKRQSNRGVAPDAMCGNAVMYDAVKGKILTFGGSPDYTDSDATTNAHII TLGEPGTSPNTVFASNGLYFARTFHTSVVLPDGSTFITGGQRRGIPFEDSTPVFT PEIYVPEQDTFYKQNPNSIVRAYHSISLLLPDGRVFNGGGGLCGDCTTNHFDAQI FTPNYLYDSNGNLATRPKITRTSTQSVKVGGRITISTDSSITKASLIRYGTATHT VNTDQRRIPLTLTNNGGNSYSFQVPSDSGVALPGYWMLFVMNSAGVPSVASTIRV TQAAA 11 GOh1013 atgggcagcagccatcatcatcatcatcacagcagcggcctggtgccgcgcggca gccatatgggtaccgcctctgcccctatcggctcagccatcccgcgcaataactg ggccgtaacgtgcgacagcgcgcagagcggcaacgagtgcaataaagccatcgac ggcaataaagacaccttctggcacacgttttatggcgcaaatggcgacccgaagc caccgcatacctataccattgacatgaaaaccacccagaatgtgaacgggctgtc cgtgctgccgcgccaggacggcaatcagaacggatggatcggccgtcacgaggta tatttaagctccgacggcaccaactggggatccccggtcgcgtcgggcagctggt tcgccgacagcaccaccaagtattccaattttgaaacccgtcctgcacgctacgt gcgcttagtggccgtgacagaggcgaacggccagccatggacctcaatcgccgaa atcaatgtattccaagccagctcctataccgcgccgcagccaggacttgggcgtt ggggcccgaccatcgacctgcctatcgtacccgcagccgcggcgattgaaccaac gtcaggccgcgtactgatgtggagcagctaccgtaacgacgcgttcgaaggcagc ccgggcggcatcactctgacgtcgagttgggatccatccacgggcatcgtctccg accgcaccgtgaccgtcacgaaacacgacatgttttgcccggggatcagcatgga cggcaacggccagatcgtcgtcacgggcggcaatgacgccaagaagacgagcctc tatgacagtagcagcgacagttggatcccggggccggacatgcaggtggcacgcg ggtaccagtccagcgcgaccatgtcagacggccgtgtctttacaatcggcggctc atttagtggcggagtgtttgagaagaatggcgaagtctatagcccctcatccaaa acgtggacgtcacttccgaacgcgaaggtgaatcccatgttaaccgccgacaaac agggcctgtacatgagcgacaaccatgcgtggctgttcggctggaagaaggggag cgtctttcaggcgggcccgtcgaccgcaatgaattggtattacacgtcaggaagc ggggacgtgaaatcagccggcaagcgccagtcgaaccgcggcgtggcgccggacg caatgtgcggcaatgccgtgatgtatgacgcggtcaaaggcaagatcctgacatt tggcgggagtccggactacaccgacagtgacgcgacaaccaatgcccacattatt acccttggggagccggggacgagcccgaacacggtcttcgcgtccaatggcctct atttcgcgcgtacctttcatacgtcggtggtcctgccggacggatcaacctttat caccggcggacagcgccgtggcatccccttcgaagactcgacccccgtctttaca ccggagatttatgtgccggaacaggacacgttttataaacagaatccgaactcga ttgtacgcgcgtatcactccatcagccttcttctcccggacggacgtgtctttaa tggcggaggaggaggttgcggggactgcacgaccaatcattttgacgcgcagatc tttaccccgaattatctgtatgattcaaatgggaatctcgcgacccgtccgaaaa ttacccgtacatcaacccagtccgtcaaagtgggcggccgcattacgatcagtac cgacagcagcattaccaaagcgtcactgattcgttacggcaccgcaacccataca gtcaacacggaccagcgccgtattccgttaaccctgaccaataacggtggcaatt cgtatagcttccaggtaccgtcggactcgggcgtggcgctgccaggatactggat gctgtttgtgatgaatagcgcgggcgtcccgagcgtagcgagcacgatccgtgtg acccaggccgcagcttgataa 12 GOh1013 MGSSHHHHHHSSGLVPRGSHMGTASAPIGSAIPRNNWAVTCDSAQSGNECNKAID GNKDTFWHTFYGANGDPKPPHTYTIDMKTTQNVNGLSVLPRQDGNQNGWIGRHEV YLSSDGTNWGSPVASGSWFADSTTKYSNFETRPARYVRLVAVTEANGQPWTSIAE INVFQASSYTAPQPGLGRWGPTIDLPIVPAAAAIEPTSGRVLMWSSYRNDAFEGS PGGITLTSSWDPSTGIVSDRTVTVTKHDMFCPGISMDGNGQIVVTGGNDAKKTSL YDSSSDSWIPGPDMQVARGYQSSATMSDGRVFTIGGSFSGGVFEKNGEVYSPSSK TWTSLPNAKVNPMLTADKQGLYMSDNHAWLFGWKKGSVFQAGPSTAMNWYYTSGS GDVKSAGKRQSNRGVAPDAMCGNAVMYDAVKGKILTFGGSPDYTDSDATTNAHII TLGEPGTSPNTVFASNGLYFARTFHTSVVLPDGSTFITGGQRRGIPFEDSTPVFT PEIYVPEQDTFYKQNPNSIVRAYHSISLLLPDGRVFNGGGGGCGDCTTNHFDAQI FTPNYLYDSNGNLATRPKITRTSTQSVKVGGRITISTDSSITKASLIRYGTATHT VNTDQRRIPLTLTNNGGNSYSFQVPSDSGVALPGYWMLFVMNSAGVPSVASTIRV TQAAA 13 GOh1015 atgggcagcagccatcatcatcatcatcacagcagcggcctggtgccgcgcggca gccatatgggtaccgcctctgcccctatcggctcagccatcccgcgcaataactg ggccgtaacgtgcgacagcgcgcagagcggcaacgagtgcaataaagccatcgac ggcaataaagacaccttctggcacacgttttatggcgcaaatggcgacccgaagc caccgcatacctataccattgacatgaaaaccacccagaatgtgaacgggctgtc cgtgctgccgcgccaggacggcaatcagaacggatggatcggccgtcacgaggta tatttaagctccgacggcaccaactggggatccccggtcgcgtcgggcagctggt tcgccgacagcaccaccaagtattccaattttgaaacccgtcctgcacgctacgt gcgcttagtggccgtgacagaggcgaacggccagccatggacctcaatcgccgaa atcaatgtattccaagccagctcctataccgcgccgcagccaggacttgggcgtt ggggcccgaccatcgacctgcctatcgtacccgcagccgcggcgattgaaccaac gtcaggccgcgtactgatgtggagcagctaccgtaacgacgcggttgaaggcagc ccgggggcatcactctgacgtcgagttgggatccatccacgggcatcgtctccga ccgcaccgtgaccgtcacgaaacacgacatgttttgcccggggatcagcatggac ggcaacggccagatcgtcgtcacgggcggcaatgacgccaagaagacgagcctct atgacagtagcagcgacagttggatcccggggccggacatgcaggtggcacgcgg gtaccagtccagcgcgaccatgtcagacggccgtgtctttacaatcggcggctca tttagtggcggagtgtttgagaagaatggcgaagtctatagcccctcatccaaaa cgtggacgtcacttccgaacgcgaaggtgaatcccatgttaaccgccgacaaaca gggcctgtacatgagcgacaaccatgcgtggctgttcggctggaagaaggggagc gtctttcaggcgggcccgtcgaccgcaatgaattggtattacacgtcaggaagcg gggacgtgaaatcagccggcaagcgccagtcgaaccgcggcgtggcgccggacgc aatgtgcggcaatgccgtgatgtatgacgcggtcaaaggcaagatcctgacattt ggcgggagtccggactacaccgacagtgacgcgacaaccaatgcccacattatta cccttggggagccggggacgagcccgaacacggtcttcgcgtccaatggcctcta tttcgcgcgtacctttcatacgtcggtggtcctgccggacggatcaacctttatc accggcggacagcgccgtggcatccccttcgaagactcgacccccgtctttacac cggagatttatgtgccggaacaggacacgttttataaacagaatccgaactcgat tgtacgcgcgtatcactccatcagccttcttctcccggacggacgtgtctttaat ggcggaggaggactgtgcggggactgcacgaccaatcattttgacgcgcagatct ttaccccgaattatctgtatgattcaaatgggaatctcgcgacccgtccgaaaat tacccgtacatcaacccagtccgtcaaagtgggcggccgcattacgatcagtacc gacagcagcattaccaaagcgtcactgattcgttacggcaccgcaacccatacag tcaacacggaccagcgccgtattccgttaaccctgaccaataacggtggcaattc gtatagcttccaggtaccgtcggactcgggcgtggcgctgccaggatactggatg ctgtttgtgatgaatagcgcgggcgtcccgagcgtagcgagcacgatccgtgtga cccaggccgcagcttgataa 14 GOh1015 MGSSHHHHHHSSGLVPRGSHMGTASAPIGSAIPRNNWAVTCDSAQSGNECNKAID GNKDTFWHTFYGANGDPKPPHTYTIDMKTTQNVNGLSVLPRQDGNQNGWIGRHEV YLSSDGTNWGSPVASGSWFADSTTKYSNFETRPARYVRLVAVTEANGQPWTSIAE INVFQASSYTAPQPGLGRWGPTIDLPIVPAAAAIEPTSGRVLMWSSYRNDAVEGS PGGITLTSSWDPSTGIVSDRTVTVTKHDMFCPGISMDGNGQIVVTGGNDAKKTSL YDSSSDSWIPGPDMQVARGYQSSATMSDGRVFTIGGSFSGGVFEKNGEVYSPSSK TWTSLPNAKVNPMLTADKQGLYMSDNHAWLFGWKKGSVFQAGPSTAMNWYYTSGS GDVKSAGKRQSNRGVAPDAMCGNAVMYDAVKGKILTFGGSPDYTDSDATTNAHII TLGEPGTSPNTVFASNGLYFARTFHTSVVLPDGSTFITGGQRRGIPFEDSTPVFT PEIYVPEQDTFYKQNPNSIVRAYHSISLLLPDGRVFNGGGGLCGDCTTNHFDAQI FTPNYLYDSNGNLATRPKITRTSTQSVKVGGRITISTDSSITKASLIRYGTATHT VNTDQRRIPLTLTNNGGNSYSFQVPSDSGVALPGYWMLFVMNSAGVPSVASTIRV TQAAA 15 GOh1016 atgggcagcagccatcatcatcatcatcacagcagcggcctggtgccgcgcggca gccatatgggtaccgcctctgcccctatcggctcagccatcccgcgcaataactg ggccgtaacgtgcgacagcgcgcagagcggcaacgagtgcaataaagccatcgac ggcaataaagacaccttctggcacacgttttatggcgcaaatggcgacccgaagc caccgcatacctataccattgacatgaaaaccacccagaatgtgaacgggctgtc cgtgctgccgcgccaggacggcaatcagaacggatggatcggccgtcacgaggta tatttaagctccgacggcaccaactggggatccccggtcgcgtcgggcagctggt tcgccgacagcaccaccaagtattccaattttgaaacccgtcctgcacgctacgt gcgcttagtggccgtgacagaggcgaacggccagccatggacctcaatcgccgaa atcaatgtattccaagccagctcctataccgcgccgcagccaggacttgggcgtt ggggcccgaccatcgacctgcctatcgtacccgcagccgcggcgattgaaccaac gtcaggccgcgtactgatgtggagcagctaccgtaacgacgcgccggaaggcagc ccgggcggcatcactctgacgtcgagttgggatccatccacgggcatcgtctccg accgcaccgtgaccgtcacgaaacacgacatgttttgcccggggatcagcatgga cggcaacggccagatcgtcgtcacgggcggcaatgacgccaagaagacgagcctc tatgacagtagcagcgacagttggatcccggggccggacatgcaggtggcacgcg ggtaccagtccagcgcgaccatgtcagacggccgtgtctttacaatcggcggctc atttagtggcggagtgtttgagaagaatggcgaagtctatagcccctcatccaaa acgtggacgtcacttccgaacgcgaaggtgaatcccatgttaaccgccgacaaac agggcctgtacatgagcgacaaccatgcgtggctgttcggctggaagaaggggag cgtctttcaggcgggcccgtcgaccgcaatgaattggtattacacgtcaggaagc ggggacgtgaaatcagccggcaagcgccagtcgaaccgcggcgtggcgccggacg caatgtgcggcaatgccgtgatgtatgacgcggtcaaaggcaagatcctgacatt tggcgggagtccggactacaccgacagtgacgcgacaaccaatgcccacattatt acccttggggagccggggacgagcccgaacacggtcttcgcgtccaatggcctct atttcgcgcgtacctttcatacgtcggtggtcctgccggacggatcaacctttat caccggcggacagcgccgtggcatccccttcgaagactcgacccccgtctttaca ccggagatttatgtgccggaacaggacacgttttataaacagaatccgaactcga ttgtacgcgcgtatcactccatcagccttcttctcccggacggacgtgtctttaa tggcggaggaggactgtgcggggactgcacgaccaatcattttgacgcgcagatc tttaccccgaattatctgtatgattcaaatgggaatctcgcgacccgtccgaaaa ttacccgtacatcaacccagtccgtcaaagtgggcggccgcattacgatcagtac cgacagcagcattaccaaagcgtcactgattcgttacggcaccgcaacccataca gtcaacacggaccagcgccgtattccgttaaccctgaccaataacggtggcaatt cgtatagcttccaggtaccgtcggactcgggcgtggcgctgccaggatactggat gctgtttgtgatgaatagcgcgggcgtcccgagcgtagcgagcacgatccgtgtg acccaggccgcagcttgataa 16 GOh1016 MGSSHHHHHHSSGLVPRGSHMGTASAPIGSAIPRNNWAVTCDSAQSGNECNKAID GNKDTFWHTFYGANGDPKPPHTYTIDMKTTQNVNGLSVLPRQDGNQNGWIGRHEV YLSSDGTNWGSPVASGSWFADSTTKYSNFETRPARYVRLVAVTEANGQPWTSIAE INVFQASSYTAPQPGLGRWGPTIDLPIVPAAAAIEPTSGRVLMWSSYRNDAPEGS PGGITLTSSWDPSTGIVSDRTVTVTKHDMFCPGISMDGNGQIVVTGGNDAKKTSL YDSSSDSWIPGPDMQVARGYQSSATMSDGRVFTIGGSFSGGVFEKNGEVYSPSSK TWTSLPNAKVNPMLTADKQGLYMSDNHAWLFGWKKGSVFQAGPSTAMNWYYTSGS GDVKSAGKRQSNRGVAPDAMCGNAVMYDAVKGKILTFGGSPDYTDSDATTNAHII TLGEPGTSPNTVFASNGLYFARTFHTSVVLPDGSTFITGGQRRGIPFEDSTPVFT PEIYVPEQDTFYKQNPNSIVRAYHSISLLLPDGRVFNGGGGLCGDCTTNHFDAQI FTPNYLYDSNGNLATRPKITRTSTQSVKVGGRITISTDSSITKASLIRYGTATHT VNTDQRRIPLTLTNNGGNSYSFQVPSDSGVALPGYWMLFVMNSAGVPSVASTIRV TQAAA 17 GOh1017 atgggcagcagccatcatcatcatcatcacagcagcggcctggtgccgcgcggca gccatatgggtaccgcctctgcccctatcggctcagccatcccgcgcaataactg ggccgtaacgtgcgacagcgcgcagagcggcaacgagtgcaataaagccatcgac ggcaataaagacaccttctggcacacgttttatggcgcaaatggcgacccgaagc caccgcatacctataccattgacatgaaaaccacccagaatgtgaacgggctgtc cgtgctgccgcgccaggacggcaatcagaacggatggatcggccgtcacgaggta tatttaagctccgacggcaccaactggggatccccggtcgcgtcgggcagctggt tcgccgacagcaccaccaagtattccaattttgaaacccgtcctgcacgctacgt gcgcttagtggccgtgacagaggcgaacggccagccatggacctcaatcgccgaa atcaatgtattccaagccagctcctataccgcgccgcagccaggacttgggcgtt ggggcccgaccatcgacctgcctatcgtacccgcagccgcggcgattgaaccaac gtcaggccgcgtactgatgtggagcagctaccgtaacgacgcgcaggaaggcagc ccgggcggcatcactctgacgtcgagttgggatccatccacgggcatcgtctccg accgcaccgtgaccgtcacgaaacacgacatgttttgcccggggatcagcatgga cggcaacggccagatcgtcgtcacgggcggcaatgacgccaagaagacgagcctc tatgacagtagcagcgacagttggatcccggggccggacatgcaggtggcacgcg ggtaccagtccagcgcgaccatgtcagacggccgtgtctttacaatcggcggctc atttagtggcggagtgtttgagaagaatggcgaagtctatagcccctcatccaaa acgtggacgtcacttccgaacgcgaaggtgaatcccatgttaaccgccgacaaac agggcctgtacatgagcgacaaccatgcgtggctgttcggctggaagaaggggag cgtctttcaggcgggcccgtcgaccgcaatgaattggtattacacgtcaggaagc ggggacgtgaaatcagccggcaagcgccagtcgaaccgcggcgtggcgccggacg caatgtgcggcaatgccgtgatgtatgacgcggtcaaaggcaagatcctgacatt tggcgggagtccggactacaccgacagtgacgcgacaaccaatgcccacattatt acccttggggagccggggacgagcccgaacacggtcttcgcgtccaatggcctct atttcgcgcgtacctttcatacgtcggtggtcctgccggacggatcaacctttat caccggcggacagcgccgtggcatccccttcgaagactcgacccccgtctttaca ccggagatttatgtgccggaacaggacacgttttataaacagaatccgaactcga ttgtacgcgcgtatcactccatcagccttcttctcccggacggacgtgtctttaa tggcggaggaggactgtgcggggactgcacgaccaatcattttgacgcgcagatc tttaccccgaattatctgtatgattcaaatgggaatctcgcgacccgtccgaaaa ttacccgtacatcaaccc 18 GOh1017 agtccgtcaaagtgggcggccgcattacgatcagtaccgacagcagcattaccaa agcgtcactgattcgttacggcaccgcaacccatacagtcaacacggaccagcgc cgtattccgttaaccctgaccaataacggtggcaattcgtatagcttccaggtac cgtcggactcgggcgtggcgctgccaggatactggatgctgtttgtgatgaatag cgcgggcgtcccgagcgtagcgagcacgatccgtgtgacccaggccgcagcttga taaMGSSHHHHHHSSGLVPRGSHMGTASAPIGSAIPRNNWAVTCDSAQSGNECNK AIDGNKDTFWHTFYGANGDPKPPHTYTIDMKTTQNVNGLSVLPRQDGNQNGWIGR HEVYLSSDGTNWGSPVASGSWFADSTTKYSNFETRPARYVRLVAVTEANGQPWTS IAEINVFQASSYTAPQPGLGRWGPTIDLPIVPAAAAIEPTSGRVLMWSSYRNDAQ EGSPGGITLTSSWDPSTGIVSDRTVTVTKHDMFCPGISMDGNGQIVVTGGNDAKK TSLYDSSSDSWIPGPDMQVARGYQSSATMSDGRVFTIGGSFSGGVFEKNGEVYSP SSKTWTSLPNAKVNPMLTADKQGLYMSDNHAWLFGWKKGSVFQAGPSTAMNWYYT SGSGDVKSAGKRQSNRGVAPDAMCGNAVMYDAVKGKILTFGGSPDYTDSDATTNA HIITLGEPGTSPNTVFASNGLYFARTFHTSVVLPDGSTFITGGQRRGIPFEDSTP VFTPEIYVPEQDTFYKQNPNSIVRAYHSISLLLPDGRVFNGGGGLCGDCTTNHFD AQIFTPNYLYDSNGNLATRPKITRTSTQSVKVGGRITISTDSSITKASLIRYGTA THTVNTDQRRIPLTLTNNGGNSYSFQVPSDSGVALPGYWMLFVMNSAGVPSVAST IRVTQAAA 19 GOh1018 atgggcagcagccatcatcatcatcatcacagcagcggcctggtgccgcgcggca gccatatgggtaccgcctctgcccctatcggctcagccatcccgcgcaataactg ggccgtaacgtgcgacagcgcgcagagcggcaacgagtgcaataaagccatcgac ggcaataaagacaccttctggcacacgttttatggcgcaaatggcgacccgaagc caccgcatacctataccattgacatgaaaaccacccagaatgtgaacgggctgtc cgtgctgccgcgccaggacggcaatcagaacggatggatcggccgtcacgaggta tatttaagctccgacggcaccaactggggatccccggtcgcgtcgggcagctggt tcgccgacagcaccaccaagtattccaattttgaaacccgtcctgcacgctacgt gcgcttagtggccgtgacagaggcgaacggccagccatggacctcaatcgccgaa atcaatgtattccaagccagctcctataccgcgccgcagccaggacttgggcgtt ggggcccgaccatcgacctgcctatcgtacccgcagccgcggcgattgaaccaac gtcaggccgcgtactgatgtggagcagctaccgtaacgacgcgaatgaaggcagc ccgggcggcatcactctgacgtcgagttgggatccatccacgggcatcgtctccg accgcaccgtgaccgtcacgaaacacgacatgttttgcccggggatcagcatgga cggcaacggccagatcgtcgtcacgggcggcaatgacgccaagaagacgagcctc tatgacagtagcagcgacagttggatcccggggccggacatgcaggtggcacgcg ggtaccagtccagcgcgaccatgtcagacggccgtgtctttacaatcggcggctc atttagtggcggagtgtttgagaagaatggcgaagtctatagcccctcatccaaa acgtggacgtcacttccgaacgcgaaggtgaatcccatgttaaccgccgacaaac agggcctgtacatgagcgacaaccatgcgtggctgttcggctggaagaaggggag cgtctttcaggcgggcccgtcgaccgcaatgaattggtattacacgtcaggaagc ggggacgtgaaatcagccggcaagcgccagtcgaaccgcggcgtggcgccggacg caatgtgcggcaatgccgtgatgtatgacgcggtcaaaggcaagatcctgacatt tgggggagtccggactacaccgacagtgacgcgacaaccaatgcccacattatta cccttggggagccggggacgagcccgaacacggtcttcgcgtccaatggcctcta tttcgcgcgtacctttcatacgtcggtggtcctgccggacggatcaacctttatc accggcggacagcgccgtggcatccccttcgaagactcgacccccgtctttacac cggagatttatgtgccggaacaggacacgttttataaacagaatccgaactcgat tgtacgcgcgtatcactccatcagccttcttctcccggacggacgtgtctttaat ggcggaggaggactgtgcggggactgcacgaccaatcattttgacgcgcagatct ttaccccgaattatctgtatgattcaaatgggaatctcgcgacccgtccgaaaat tacccgtacatcaacccagtccgtcaaagtgggcggccgcattacgatcagtacc gacagcagcattaccaaagcgtcactgattcgttacggcaccgcaacccatacag tcaacacggaccagcgccgtattccgttaaccctgaccaataacggtggcaattc gtatagcttccaggtaccgtcggactcgggcgtggcgctgccaggatactggatg ctgtttgtgatgaatagcgcgggcgtcccgagcgtagcgagcacgatccgtgtga cccaggccgcagcttgataa 20 GOh1018 MGSSHHHHHHSSGLVPRGSHMGTASAPIGSAIPRNNWAVTCDSAQSGNECNKAID GNKDTFWHTFYGANGDPKPPHTYTIDMKTTQNVNGLSVLPRQDGNQNGWIGRHEV YLSSDGTNWGSPVASGSWFADSTTKYSNFETRPARYVRLVAVTEANGQPWTSIAE INVFQASSYTAPQPGLGRWGPTIDLPIVPAAAAIEPTSGRVLMWSSYRNDANEGS PGGITLTSSWDPSTGIVSDRTVTVTKHDMFCPGISMDGNGQIVVTGGNDAKKTSL YDSSSDSWIPGPDMQVARGYQSSATMSDGRVFTIGGSFSGGVFEKNGEVYSPSSK TWTSLPNAKVNPMLTADKQGLYMSDNHAWLFGWKKGSVFQAGPSTAMNWYYTSGS GDVKSAGKRQSNRGVAPDAMCGNAVMYDAVKGKILTFGGSPDYTDSDATTNAHII TLGEPGTSPNTVFASNGLYFARTFHTSVVLPDGSTFITGGQRRGIPFEDSTPVFT PEIYVPEQDTFYKQNPNSIVRAYHSISLLLPDGRVFNGGGGLCGDCTTNHFDAQI FTPNYLYDSNGNLATRPKITRTSTQSVKVGGRITISTDSSITKASLIRYGTATHT VNTDQRRIPLTLTNNGGNSYSFQVPSDSGVALPGYWMLFVMNSAGVPSVASTIRV TQAAA 21 GOh1020 atgggcagcagccatcatcatcatcatcacagcagcggcctggtgccgcgcggca gccatatgggtaccgcctctgcccctatcggctcagccatcccgcgcaataactg ggccgtaacgtgcgacagcgcgcagagcggcaacgagtgcaataaagccatcgac ggcaataaagacaccttctggcacacgttttatggcgcaaatggcgacccgaagc caccgcatacctataccattgacatgaaaaccacccagaatgtgaacgggctgtc cgtgctgccgcgccaggacggcaatcagaacggatggatcggccgtcacgaggta tatttaagctccgacggcaccaactggggatccccggtcgcgtcgggcagctggt tcgccgacagcaccaccaagtattccaattttgaaacccgtcctgcacgctacgt gcgcttagtggccgtgacagaggcgaacggccagccatggacctcaatcgccgaa atcaatgtattccaagccagctcctataccgcgccgcagccaggacttgggcgtt ggggcccgaccatcgacctgcctatcgtacccgcagccgcggcgattgaaccaac gtcaggccgcgtactgatgtggagcagctaccgtaacgacgcgtctgaaggcagc ccgggcggcatcactctgacgtcgagttgggatccatccacgggcatcgtctccg accgcaccgtgaccgtcacgaaacacgacatgttttgcccggggatcagcatgga cggcaacggccagatcgtcgtcacgggcggcaatgacgccaagaagacgagcctc tatgacagtagcagcgacagttggatcccggggccggacatgcaggtggcacgcg ggtaccagtccagcgcgaccatgtcagacggccgtgtctttacaatcggcggctc atttagtggcggagtgtttgagaagaatggcgaagtctatagcccctcatccaaa acgtggacgtcacttccgaacgcgaaggtgaatcccatgttaaccgccgacaaac agggcctgtacatgagcgacaaccatgcgtggctgttcggctggaagaaggggag cgtctttcaggcgggcccgtcgaccgcaatgaattggtattacacgtcaggaagc ggggacgtgaaatcagccggcaagcgccagtcgaaccgcggcgtggcgccggacg caatgtgcggcaatgccgtgatgtatgacgcggtcaaaggcaagatcctgacatt tggcgggagtccggactacaccgacagtgacgcgacaaccaatgcccacattatt acccttggggagccggggacgagcccgaacacggtcttcgcgtccaatggcctct atttcgcgcgtacctttcatacgtcggtggtcctgccggacggatcaacctttat caccggcggacagcgccgtggcatccccttcgaagactcgacccccgtctttaca ccggagatttatgtgccggaacaggacacgttttataaacagaatccgaactcga ttgtacgcgcgtatcactccatcagccttcttctcccggacggacgtgtctttaa tggcggaggaggactgtgcggggactgcacgaccaatcattttgacgcgcagatc tttaccccgaattatctgtatgattcaaatgggaatctcgcgacccgtccgaaaa ttacccgtacatcaacccagtccgtcaaagtgggcggccgcattacgatcagtac cgacagcagcattaccaaagcgtcactgattcgttacggcaccgcaacccataca gtcaacacggaccagcgccgtattccgttaaccctgaccaataacggtggcaatt cgtatagcttccaggtaccgtcggactcgggcgtggcgctgccaggatactggat gctgtttgtgatgaatagcgcgggcgtcccgagcgtagcgagcacgatccgtgtg acccaggccgcagcttgataa 22 GOh1020 MGSSHHHHHHSSGLVPRGSHMGTASAPIGSAIPRNNWAVTCDSAQSGNECNKAID GNKDTFWHTFYGANGDPKPPHTYTIDMKTTQNVNGLSVLPRQDGNQNGWIGRHEV YLSSDGTNWGSPVASGSWFADSTTKYSNFETRPARYVRLVAVTEANGQPWTSIAE INVFQASSYTAPQPGLGRWGPTIDLPIVPAAAAIEPTSGRVLMWSSYRNDASEGS PGGITLTSSWDPSTGIVSDRTVTVTKHDMFCPGISMDGNGQIVVTGGNDAKKTSL YDSSSDSWIPGPDMQVARGYQSSATMSDGRVFTIGGSFSGGVFEKNGEVYSPSSK TWTSLPNAKVNPMLTADKQGLYMSDNHAWLFGWKKGSVFQAGPSTAMNWYYTSGS GDVKSAGKRQSNRGVAPDAMCGNAVMYDAVKGKILTFGGSPDYTDSDATTNAHII TLGEPGTSPNTVFASNGLYFARTFHTSVVLPDGSTFITGGQRRGIPFEDSTPVFT PEIYVPEQDTFYKQNPNSIVRAYHSISLLLPDGRVFNGGGGLCGDCTTNHFDAQI FTPNYLYDSNGNLATRPKITRTSTQSVKVGGRITISTDSSITKASLIRYGTATHT VNTDQRRIPLTLTNNGGNSYSFQVPSDSGVALPGYWMLFVMNSAGVPSVASTIRV TQAAA 23 GOh1021 atgggcagcagccatcatcatcatcatcacagcagcggcctggtgccgcgcggca gccatatgggtaccgcctctgcccctatcggctcagccatcccgcgcaataactg ggccgtaacgtgcgacagcgcgcagagcggcaacgagtgcaataaagccatcgac ggcaataaagacaccttctggcacacgttttatggcgcaaatggcgacccgaagc caccgcatacctataccattgacatgaaaaccacccagaatgtgaacgggctgtc cgtgctgccgcgccaggacggcaatcagaacggatggatcggccgtcacgaggta tatttaagctccgacggcaccaactggggatccccggtcgcgtcgggcagctggt tcgccgacagcaccaccaagtattccaattttgaaacccgtcctgcacgctacgt gcgcttagtggccgtgacagaggcgaacggccagccatggacctcaatcgccgaa atcaatgtattccaagccagctcctataccgcgccgcagccaggacttgggcgtt ggggcccgaccatcgacctgcctatcgtacccgcagccgcggcgattgaaccaac gtcaggccgcgtactgatgtggagcagctaccgtaacgacgcgttcgaaggcagc ccgggcggcatcactctgacgtcgagttgggatccatccacgggcatcgtctccg accgcaccgtgaccgtcacgaaacacgacatgttttgcccggggatcagcatgga cggcaacggccagatcgtcgtcacgggcggctgggacgccaagaagacgagcctc tatgacagtagcagcgacagttggatcccggggccggacatgcaggtggcacgcg ggtaccagtccagcgcgaccatgtcagacggccgtgtctttacaatcggcggctc atttagtggcggagtgtttgagaagaatggcgaagtctatagcccctcatccaaa acgtggacgtcacttccgaacgcgaaggtgaatcccatgttaaccgccgacaaac agggcctgtacatgagcgacaaccatgcgtggctgttcggctggaagaaggggag cgtctttcaggcgggcccgtcgaccgcaatgaattggtattacacgtcaggaagc ggggacgtgaaatcagccggcaagcgccagtcgaaccgcggcgtggcgccggacg caatgtgcggcaatgccgtgatgtatgacgcggtcaaaggcaagatcctgacatt tggcgggagtccggactacaccgacagtgacgcgacaaccaatgcccacattatt acccttggggagccggggacgagcccgaacacggtcttcgcgtccaatggcctct atttcgcgcgtacctttcatacgtcggtggtcctgccggacggatcaacctttat caccggcggacagcgccgtggcatccccttcgaagactcgacccccgtctttaca ccggagatttatgtgccggaacaggacacgttttataaacagaatccgaactcga ttgtacgcgcgtatcactccatcagccttcttctcccggacggacgtgtctttaa tggcggaggaggactgtgcggggactgcacgaccaatcattttgacgcgcagatc tttaccccgaattatctgtatgattcaaatgggaatctcgcgacccgtccgaaaa ttacccgtacatcaacccagtccgtcaaagtgggcggccgcattacgatcagtac cgacagcagcattaccaaagcgtcactgattcgttacggcaccgcaacccataca gtcaacacggaccagcgccgtattccgttaaccctgaccaataacggtggcaatt cgtatagcttccaggtaccgtcggactcgggcgtggcgctgccaggatactggat gctgtttgtgatgaatagcgcgggcgtcccgagcgtagcgagcacgatccgtgtg acccaggccgcagcttgataa 24 GOh1021 MGSSHHHHHHSSGLVPRGSHMGTASAPIGSAIPRNNWAVTCDSAQSGNECNKAID GNKDTFWHTFYGANGDPKPPHTYTIDMKTTQNVNGLSVLPRQDGNQNGWIGRHEV YLSSDGTNWGSPVASGSWFADSTTKYSNFETRPARYVRLVAVTEANGQPWTSIAE INVFQASSYTAPQPGLGRWGPTIDLPIVPAAAAIEPTSGRVLMWSSYRNDAFEGS PGGITLTSSWDPSTGIVSDRTVTVTKHDMFCPGISMDGNGQIVVTGGWDAKKTSL YDSSSDSWIPGPDMQVARGYQSSATMSDGRVFTIGGSFSGGVFEKNGEVYSPSSK TWTSLPNAKVNPMLTADKQGLYMSDNHAWLFGWKKGSVFQAGPSTAMNWYYTSGS GDVKSAGKRQSNRGVAPDAMCGNAVMYDAVKGKILTFGGSPDYTDSDATTNAHII TLGEPGTSPNTVFASNGLYFARTFHTSVVLPDGSTFITGGQRRGIPFEDSTPVFT PEIYVPEQDTFYKQNPNSIVRAYHSISLLLPDGRVFNGGGGLCGDCTTNHFDAQI FTPNYLYDSNGNLATRPKITRTSTQSVKVGGRITISTDSSITKASLIRYGTATHT VNTDQRRIPLTLTNNGGNSYSFQVPSDSGVALPGYWMLFVMNSAGVPSVASTIRV TQAAA 25 GOh1025 atgggcagcagccatcatcatcatcatcacagcagcggcctggtgccgcgcggca gccatatgggtaccgcctctgcccctatcggctcagccatcccgcgcaataactg ggccgtaacgtgcgacagcgcgcagagcggcaacgagtgcaataaagccatcgac ggcaataaagacaccttctggcacacgttttatggcgcaaatggcgacccgaagc caccgcatacctataccattgacatgaaaaccacccagaatgtgaacgggctgtc cgtgctgccgcgccaggacggcaatcagaacggatggatcggccgtcacgaggta tatttaagctccgacggcaccaactggggatccccggtcgcgtcgggcagctggt tcgccgacagcaccaccaagtattccaattttgaaacccgtcctgcacgctacgt gcgcttagtggccgtgacagaggcgaacggccagccatggacctcaatcgccgaa atcaatgtattccaagccagctcctataccgcgccgcagccaggacttgggcgtt ggggcccgaccatcgacctgcctatcgtacccgcagccgcggcgattgaaccaac gtcaggccgcgtactgatgtggagcagctaccgtaacgacgcgttccctggcagc ccgggggcatcactctgacgtcgagttgggatccatccacgggcatcgtctccga ccgcaccgtgaccgtcacgaaacacgacatgttttgcccggggatcagcatggac ggcaacggccagatcgtcgtcacgggcggcaatgacgccaagaagacgagcctct atgacagtagcagcgacagttggatcccggggccggacatgcaggtggcacgcgg gtaccagtccagcgcgaccatgtcagacggccgtgtctttacaatcggcggctca tttagtggcggagtgtttgagaagaatggcgaagtctatagcccctcatccaaaa cgtggacgtcacttccgaacgcgaaggtgaatcccatgttaaccgccgacaaaca gggcctgtacatgagcgacaaccatgcgtggctgttcggctggaagaaggggagc gtctttcagggggcccgtcgaccgcaatgaattggtattacacgtcaggaagcgg ggacgtgaaatcagccggcaagcgccagtcgaaccgcggcgtggcgccggacgca atgtgcggcaatgccgtgatgtatgacgcggtcaaaggcaagatcctgacatttg gcgggagtccggactacaccgacagtgacgcgacaaccaatgcccacattattac ccttggggagccggggacgagcccgaacacggtcttcgcgtccaatggcctctat ttcgcgcgtacctttcatacgtcggtggtcctgccggacggatcaacctttatca ccggcggacagcgccgtggcatccccttcgaagactcgacccccgtctttacacc ggagatttatgtgccggaacaggacacgttttataaacagaatccgaactcgatt gtacgcgcgtatcactccatcagccttcttctcccggacggacgtgtctttaatg gcggaggaggactgtgcggggactgcacgaccaatcattttgacgcgcagatctt taccccgaattatctgtatgattcaaatgggaatctcgcgacccgtccgaaaatt acccgtacatcaacccagtccgtcaaagtgggcggccgcattacgatcagtaccg acagcagcattaccaaagcgtcactgattcgttacggcaccgcaacccatacagt caacacggaccagcgccgtattccgttaaccctgaccaataacggtggcaattcg tatagcttccaggtaccgtcggactcgggcgtggcgctgccaggatactggatgc tgtttgtgatgaatagcgcgggcgtcccgagcgtagcgagcacgatccgtgtgac ccaggccgcagcttgataa 26 GOh1025 MGSSHHHHHHSSGLVPRGSHMGTASAPIGSAIPRNNWAVTCDSAQSGNECNKAID GNKDTFWHTFYGANGDPKPPHTYTIDMKTTQNVNGLSVLPRQDGNQNGWIGRHEV YLSSDGTNWGSPVASGSWFADSTTKYSNFETRPARYVRLVAVTEANGQPWTSIAE INVFQASSYTAPQPGLGRWGPTIDLPIVPAAAAIEPTSGRVLMWSSYRNDAFPGS PGGITLTSSWDPSTGIVSDRTVTVTKHDMFCPGISMDGNGQIVVTGGNDAKKTSL YDSSSDSWIPGPDMQVARGYQSSATMSDGRVFTIGGSFSGGVFEKNGEVYSPSSK TWTSLPNAKVNPMLTADKQGLYMSDNHAWLFGWKKGSVFQAGPSTAMNWYYTSGS GDVKSAGKRQSNRGVAPDAMCGNAVMYDAVKGKILTFGGSPDYTDSDATTNAHII TLGEPGTSPNTVFASNGLYFARTFHTSVVLPDGSTFITGGQRRGIPFEDSTPVFT PEIYVPEQDTFYKQNPNSIVRAYHSISLLLPDGRVFNGGGGLCGDCTTNHFDAQI FTPNYLYDSNGNLATRPKITRTSTQSVKVGGRITISTDSSITKASLIRYGTATHT VNTDQRRIPLTLTNNGGNSYSFQVPSDSGVALPGYWMLFVMNSAGVPSVASTIRV TQAAA 27 GOh1030 atgggcagcagccatcatcatcatcatcacagcagcggcctggtgccgcgcggca gccatatgggtaccgcctctgcccctatcggctcagccatcccgcgcaataactg ggccgtaacgtgcgacagcgcgcagagcggcaacgagtgcaataaagccatcgac ggcaataaagacaccttctggcacacgttttatggcgcaaatggcgacccgaagc caccgcatacctataccattgacatgaaaaccacccagaatgtgaacgggctgtc cgtgctgccgcgccaggacggcaatcagaacggatggatcggccgtcacgaggta tatttaagctccgacggcaccaactggggatccccggtcgcgtcgggcagctggt tcgccgacagcaccaccaagtattccaattttgaaacccgtcctgcacgctacgt gcgcttagtggccgtgacagaggcgaacggccagccatggacctcaatcgccgaa atcaatgtattccaagccagctcctataccgcgccgcagccaggacttgggcgtt ggggcccgaccatcgacctgcctatcgtacccgcagccgcggcgattgaaccaac gtcaggccgcgtactgatgtggagcagctaccgtaacgacgcgattgaaggcagc ccgggcggcatcactctgacgtcgagttgggatccatccacgggcatcgtctccg accgcaccgtgaccgtcacgaaacacgacatgttttgcccggggatcagcatgga cggcaacggccagatcgtcgtcacgggcggcaatgacgccaagaagacgagcctc tatgacagtagcagcgacagttggatcccggggccggacatgcaggtggcacgcg ggtaccagtccagcgcgaccatgtcagacggccgtgtctttacaatcggcggctc atttagtggcggagtgtttgagaagaatggcgaagtctatagcccctcatccaaa acgtggacgtcacttccgaacgcgaaggtgaatcccatgttaaccgccgacaaac agggcctgtacatgagcgacaaccatgcgtggctgttcggctggaagaaggggag cgtctttcaggcgggcccgtcgaccgcaatgaattggtattacacgtcaggaagc ggggacgtgaaatcagccggcaagcgccagtcgaaccgcggcgtggcgccggacg caatgtgcggcaatgccgtgatgtatgacgcggtcaaaggcaagatcctgacatt tggcgggagtccggactacaccgacagtgacgcgacaaccaatgcccacattatt acccttggggagccggggacgagcccgaacacggtcttcgcgtccaatggcctct atttcgcgcgtacctttcatacgtcggtggtcctgccggacggatcaacctttat caccggcggacagcgccgtggcatccccttcgaagactcgacccccgtctttaca ccggagatttatgtgccggaacaggacacgttttataaacagaatccgaactcga ttgtacgcgcgtatcactccatcagccttcttctcccggacggacgtgtctttaa tggcggaggaggactgtgcggggactgcacgaccaatcattttgacgcgcagatc tttaccccgaattatctgtatgattcaaatgggaatctcgcgacccgtccgaaaa ttacccgtacatcaacccagtccgtcaaagtgggcggccgcattacgatcagtac cgacagcagcattaccaaagcgtcactgattcgttacggcaccgcaacccataca gtcaacacggaccagcgccgtattccgttaaccctgaccaataacggtggcaatt cgtatagcttccaggtaccgtcggactcgggcgtggcgctgccaggatactggat gctgtttgtgatgaatagcgcgggcgtcccgagcgtagcgagcacgatccgtgtg acccaggccgcagcttgataa 28 GOh1030 MGSSHHHHHHSSGLVPRGSHMGTASAPIGSAIPRNNWAVTCDSAQSGNECNKAID GNKDTFWHTFYGANGDPKPPHTYTIDMKTTQNVNGLSVLPRQDGNQNGWIGRHEV YLSSDGTNWGSPVASGSWFADSTTKYSNFETRPARYVRLVAVTEANGQPWTSIAE INVFQASSYTAPQPGLGRWGPTIDLPIVPAAAAIEPTSGRVLMWSSYRNDAIEGS PGGITLTSSWDPSTGIVSDRTVTVTKHDMFCPGISMDGNGQIVVTGGNDAKKTSL YDSSSDSWIPGPDMQVARGYQSSATMSDGRVFTIGGSFSGGVFEKNGEVYSPSSK TWTSLPNAKVNPMLTADKQGLYMSDNHAWLFGWKKGSVFQAGPSTAMNWYYTSGS GDVKSAGKRQSNRGVAPDAMCGNAVMYDAVKGKILTFGGSPDYTDSDATTNAHII TLGEPGTSPNTVFASNGLYFARTFHTSVVLPDGSTFITGGQRRGIPFEDSTPVFT PEIYVPEQDTFYKQNPNSIVRAYHSISLLLPDGRVFNGGGGLCGDCTTNHFDAQI FTPNYLYDSNGNLATRPKITRTSTQSVKVGGRITISTDSSITKASLIRYGTATHT VNTDQRRIPLTLTNNGGNSYSFQVPSDSGVALPGYWMLFVMNSAGVPSVASTIRV TQAAA 29 GOh1031 atgggcagcagccatcatcatcatcatcacagcagcggcctggtgccgcgcggca gccatatgggtaccgcctctgcccctatcggctcagccatcccgcgcaataactg ggccgtaacgtgcgacagcgcgcagagcggcaacgagtgcaataaagccatcgac ggcaataaagacaccttctggcacacgttttatggcgcaaatggcgacccgaagc caccgcatacctataccattgacatgaaaaccacccagaatgtgaacgggctgtc cgtgctgccgcgccaggacggcaatcagaacggatggatcggccgtcacgaggta tatttaagctccgacggcaccaactggggatccccggtcgcgtcgggcagctggt tcgccgacagcaccaccaagtattccaattttgaaacccgtcctgcacgctacgt gcgcttagtggccgtgacagaggcgaacggccagccatggacctcaatcgccgaa atcaatgtattccaagccagctcctataccgcgccgcagccaggacttgggcgtt ggggcccgaccatcgacctgcctatcgtacccgcagccgcggcgattgaaccaac gtcaggccgcgtactgatgtggagcagctaccgtaacgacgcgacggaaggcagc ccgggcggcatcactctgacgtcgagttgggatccatccacgggcatcgtctccg accgcaccgtgaccgtcacgaaacacgacatgttttgcccggggatcagcatgga cggcaacggccagatcgtcgtcacgggcggcaatgacgccaagaagacgagcctc tatgacagtagcagcgacagttggatcccggggccggacatgcaggtggcacgcg ggtaccagtccagcgcgaccatgtcagacggccgtgtctttacaatcggcggctc atttagtggcggagtgtttgagaagaatggcgaagtctatagcccctcatccaaa acgtggacgtcacttccgaacgcgaaggtgaatcccatgttaaccgccgacaaac agggcctgtacatgagcgacaaccatgcgtggctgttcggctggaagaaggggag cgtctttcaggcgggcccgtcgaccgcaatgaattggtattacacgtcaggaagc ggggacgtgaaatcagccggcaagcgccagtcgaaccgcggcgtggcgccggacg caatgtgcggcaatgccgtgatgtatgacgcggtcaaaggcaagatcctgacatt tggcgggagtccggactacaccgacagtgacgcgacaaccaatgcccacattatt acccttggggagccggggacgagcccgaacacggtcttcgcgtccaatggcctct atttcgcgcgtacctttcatacgtcggtggtcctgccggacggatcaacctttat caccggcggacagcgccgtggcatccccttcgaagactcgacccccgtctttaca ccggagatttatgtgccggaacaggacacgttttataaacagaatccgaactcga ttgtacgcgcgtatcactccatcagccttcttctcccggacggacgtgtctttaa tggcggaggaggactgtgcggggactgcacgaccaatcattttgacgcgcagatc tttaccccgaattatctgtatgattcaaatgggaatctcgcgacccgtccgaaaa ttacccgtacatcaacccagtccgtcaaagtgggcggccgcattacgatcagtac cgacagcagcattaccaaagcgtcactgattcgttacggcaccgcaacccataca gtcaacacggaccagcgccgtattccgttaaccctgaccaataacggtggcaatt cgtatagcttccaggtaccgtcggactcgggcgtggcgctgccaggatactggat gctgtttgtgatgaatagcgcgggcgtcccgagcgtagcgagcacgatccgtgtg acccaggccgcagcttgataa 30 GOh1031 MGSSHHHHHHSSGLVPRGSHMGTASAPIGSAIPRNNWAVTCDSAQSGNECNKAID GNKDTFWHTFYGANGDPKPPHTYTIDMKTTQNVNGLSVLPRQDGNQNGWIGRHEV YLSSDGTNWGSPVASGSWFADSTTKYSNFETRPARYVRLVAVTEANGQPWTSIAE INVFQASSYTAPQPGLGRWGPTIDLPIVPAAAAIEPTSGRVLMWSSYRNDATEGS PGGITLTSSWDPSTGIVSDRTVTVTKHDMFCPGISMDGNGQIVVTGGNDAKKTSL YDSSSDSWIPGPDMQVARGYQSSATMSDGRVFTIGGSFSGGVFEKNGEVYSPSSK TWTSLPNAKVNPMLTADKQGLYMSDNHAWLFGWKKGSVFQAGPSTAMNWYYTSGS GDVKSAGKRQSNRGVAPDAMCGNAVMYDAVKGKILTFGGSPDYTDSDATTNAHII TLGEPGTSPNTVFASNGLYFARTFHTSVVLPDGSTFITGGQRRGIPFEDSTPVFT PEIYVPEQDTFYKQNPNSIVRAYHSISLLLPDGRVFNGGGGLCGDCTTNHFDAQI FTPNYLYDSNGNLATRPKITRTSTQSVKVGGRITISTDSSITKASLIRYGTATHT VNTDQRRIPLTLTNNGGNSYSFQVPSDSGVALPGYWMLFVMNSAGVPSVASTIRV TQAAA 31 GOh1032 atgggcagcagccatcatcatcatcatcacagcagcggcctggtgccgcgcggca gccatatgggtaccgcctctgcccctatcggctcagccatcccgcgcaataactg ggccgtaacgtgcgacagcgcgcagagcggcaacgagtgcaataaagccatcgac ggcaataaagacaccttctggcacacgttttatggcgcaaatggcgacccgaagc caccgcatacctataccattgacatgaaaaccacccagaatgtgaacgggctgtc cgtgctgccgcgccaggacggcaatcagaacggatggatcggccgtcacgaggta tatttaagctccgacggcaccaactggggatccccggtcgcgtcgggcagctggt tcgccgacagcaccaccaagtattccaattttgaaacccgtcctgcacgctacgt gcgcttagtggccgtgacagaggcgaacggccagccatggacctcaatcgccgaa atcaatgtattccaagccagctcctataccgcgccgcagccaggacttgggcgtt ggggcccgaccatcgacctgcctatcgtacccgcagccgcggcgattgaaccaac gtcaggccgcgtactgatgtggagcagctaccgtaacgacgcgttggaaggcagc ccgggcggcatcactctgacgtcgagttgggatccatccacgggcatcgtctccg accgcaccgtgaccgtcacgaaacacgacatgttttgcccggggatcagcatgga cggcaacggccagatcgtcgtcacgggcggcaatgacgccaagaagacgagcctc tatgacagtagcagcgacagttggatcccggggccggacatgcaggtggcacgcg ggtaccagtccagcgcgaccatgtcagacggccgtgtctttacaatcggcggctc atttagtggcggagtgtttgagaagaatggcgaagtctatagcccctcatccaaa acgtggacgtcacttccgaacgcgaaggtgaatcccatgttaaccgccgacaaac agggcctgtacatgagcgacaaccatgcgtggctgttcggctggaagaaggggag cgtctttcaggcgggcccgtcgaccgcaatgaattggtattacacgtcaggaagc ggggacgtgaaatcagccggcaagcgccagtcgaaccgcggcgtggcgccggacg caatgtgcggcaatgccgtgatgtatgacgcggtcaaaggcaagatcctgacatt tggcgggagtccggactacaccgacagtgacgcgacaaccaatgcccacattatt acccttggggagccggggacgagcccgaacacggtcttcgcgtccaatggcctct atttcgcgcgtacctttcatacgtcggtggtcctgccggacggatcaacctttat caccggcggacagcgccgtggcatccccttcgaagactcgacccccgtctttaca ccggagatttatgtgccggaacaggacacgttttataaacagaatccgaactcga ttgtacgcgcgtatcactccatcagccttcttctcccggacggacgtgtctttaa tggcggaggaggactgtgcggggactgcacgaccaatcattttgacgcgcagatc tttaccccgaattatctgtatgattcaaatgggaatctcgcgacccgtccgaaaa ttacccgtacatcaacccagtccgtcaaagtgggcggccgcattacgatcagtac cgacagcagcattaccaaagcgtcactgattcgttacggcaccgcaacccataca gtcaacacggaccagcgccgtattccgttaaccctgaccaataacggtggcaatt cgtatagcttccaggtaccgtcggactcgggcgtggcgctgccaggatactggat gctgtttgtgatgaatagcgcgggcgtcccgagcgtagcgagcacgatccgtgtg acccaggccgcagcttgataa 32 GOh1032 MGSSHHHHHHSSGLVPRGSHMGTASAPIGSAIPRNNWAVTCDSAQSGNECNKAID GNKDTFWHTFYGANGDPKPPHTYTIDMKTTQNVNGLSVLPRQDGNQNGWIGRHEV YLSSDGTNWGSPVASGSWFADSTTKYSNFETRPARYVRLVAVTEANGQPWTSIAE INVFQASSYTAPQPGLGRWGPTIDLPIVPAAAAIEPTSGRVLMWSSYRNDALEGS PGGITLTSSWDPSTGIVSDRTVTVTKHDMFCPGISMDGNGQIVVTGGNDAKKTSL YDSSSDSWIPGPDMQVARGYQSSATMSDGRVFTIGGSFSGGVFEKNGEVYSPSSK TWTSLPNAKVNPMLTADKQGLYMSDNHAWLFGWKKGSVFQAGPSTAMNWYYTSGS GDVKSAGKRQSNRGVAPDAMCGNAVMYDAVKGKILTFGGSPDYTDSDATTNAHII TLGEPGTSPNTVFASNGLYFARTFHTSVVLPDGSTFITGGQRRGIPFEDSTPVFT PEIYVPEQDTFYKQNPNSIVRAYHSISLLLPDGRVFNGGGGLCGDCTTNHFDAQI FTPNYLYDSNGNLATRPKITRTSTQSVKVGGRITISTDSSITKASLIRYGTATHT VNTDQRRIPLTLTNNGGNSYSFQVPSDSGVALPGYWMLFVMNSAGVPSVASTIRV TQAAA 33 GOh1034 atgggcagcagccatcatcatcatcatcacagcagcggcctggtgccgcgcggca gccatatgggtaccgcctctgcccctatcggctcagccatcccgcgcaataactg ggccgtaacgtgcgacagcgcgcagagcggcaacgagtgcaataaagccatcgac ggcaataaagacaccttctggcacacgttttatggcgcaaatggcgacccgaagc caccgcatacctataccattgacatgaaaaccacccagaatgtgaacgggctgtc cgtgctgccgcgccaggacggcaatcagaacggatggatcggccgtcacgaggta tatttaagctccgacggcaccaactggggatccccggtcgcgtcgggcagctggt tcgccgacagcaccaccaagtattccaattttgaaacccgtcctgcacgctacgt gcgcttagtggccgtgacagaggcgaacggccagccatggacctcaatcgccgaa atcaatgtattccaagccagctcctataccgcgccgcagccaggacttgggcgtt ggggcccgaccatcgacctgcctatcgtacccgcagccgcggcgattgaaccaac gtcaggccgcgtactgatgtggagcagctaccgtaacgacgcggaggaaggcagc ccgggcggcatcactctgacgtcgagttgggatccatccacgggcatcgtctccg accgcaccgtgaccgtcacgaaacacgacatgttttgcccggggatcagcatgga cggcaacggccagatcgtcgtcacgggcggcaatgacgccaagaagacgagcctc tatgacagtagcagcgacagttggatcccggggccggacatgcaggtggcacgcg ggtaccagtccagcgcgaccatgtcagacggccgtgtctttacaatcggcggctc atttagtggcggagtgtttgagaagaatggcgaagtctatagcccctcatccaaa acgtggacgtcacttccgaacgcgaaggtgaatcccatgttaaccgccgacaaac agggcctgtacatgagcgacaaccatgcgtggctgttcggctggaagaaggggag cgtctttcaggcgggcccgtcgaccgcaatgaattggtattacacgtcaggaagc ggggacgtgaaatcagccggcaagcgccagtcgaaccgcggcgtggcgccggacg caatgtgcggcaatgccgtgatgtatgacgcggtcaaaggcaagatcctgacatt tggcgggagtccggactacaccgacagtgacgcgacaaccaatgcccacattatt acccttggggagccggggacgagcccgaacacggtcttcgcgtccaatggcctct atttcgcgcgtacctttcatacgtcggtggtcctgccggacggatcaacctttat caccggcggacagcgccgtggcatccccttcgaagactcgacccccgtctttaca ccggagatttatgtgccggaacaggacacgttttataaacagaatccgaactcga ttgtacgcgcgtatcactccatcagccttcttctcccggacggacgtgtctttaa tggcggaggaggactgtgcggggactgcacgaccaatcattttgacgcgcagatc tttaccccgaattatctgtatgattcaaatgggaatctcgcgacccgtccgaaaa ttacccgtacatcaacccagtccgtcaaagtgggcggccgcattacgatcagtac cgacagcagcattaccaaagcgtcactgattcgttacggcaccgcaacccataca gtcaacacggaccagcgccgtattccgttaaccctgaccaataacggtggcaatt cgtatagcttccaggtaccgtcggactcgggcgtggcgctgccaggatactggat gctgtttgtgatgaatagcgcgggcgtcccgagcgtagcgagcacgatccgtgtg acccaggccgcagcttgataa 34 GOh1034 MGSSHHHHHHSSGLVPRGSHMGTASAPIGSAIPRNNWAVTCDSAQSGNECNKAID GNKDTFWHTFYGANGDPKPPHTYTIDMKTTQNVNGLSVLPRQDGNQNGWIGRHEV YLSSDGTNWGSPVASGSWFADSTTKYSNFETRPARYVRLVAVTEANGQPWTSIAE INVFQASSYTAPQPGLGRWGPTIDLPIVPAAAAIEPTSGRVLMWSSYRNDAEEGS PGGITLTSSWDPSTGIVSDRTVTVTKHDMFCPGISMDGNGQIVVTGGNDAKKTSL YDSSSDSWIPGPDMQVARGYQSSATMSDGRVFTIGGSFSGGVFEKNGEVYSPSSK TWTSLPNAKVNPMLTADKQGLYMSDNHAWLFGWKKGSVFQAGPSTAMNWYYTSGS GDVKSAGKRQSNRGVAPDAMCGNAVMYDAVKGKILTFGGSPDYTDSDATTNAHII TLGEPGTSPNTVFASNGLYFARTFHTSVVLPDGSTFITGGQRRGIPFEDSTPVFT PEIYVPEQDTFYKQNPNSIVRAYHSISLLLPDGRVFNGGGGLCGDCTTNHFDAQI FTPNYLYDSNGNLATRPKITRTSTQSVKVGGRITISTDSSITKASLIRYGTATHT VNTDQRRIPLTLTNNGGNSYSFQVPSDSGVALPGYWMLFVMNSAGVPSVASTIRV TQAAA 35 GOh1035 atgggcagcagccatcatcatcatcatcacagcagcggcctggtgccgcgcggca gccatatgggtaccgcctctgcccctatcggctcagccatcccgcgcaataactg ggccgtaacgtgcgacagcgcgcagagcggcaacgagtgcaataaagccatcgac ggcaataaagacaccttctggcacacgttttatggcgcaaatggcgacccgaagc caccgcatacctataccattgacatgaaaaccacccagaatgtgaacgggctgtc cgtgctgccgcgccaggacggcaatcagaacggatggatcggccgtcacgaggta tatttaagctccgacggcaccaactggggatccccggtcgcgtcgggcagctggt tcgccgacagcaccaccaagtattccaattttgaaacccgtcctgcacgctacgt gcgcttagtggccgtgacagaggcgaacggccagccatggacctcaatcgccgaa atcaatgtattccaagccagctcctataccgcgccgcagccaggacttgggcgtt ggggcccgaccatcgacctgcctatcgtacccgcagccgcggcgattgaaccaac gtcaggccgcgtactgatgtggagcagctaccgtaacgacgcgtatgaaggcagc ccgggcggcatcactctgacgtcgagttgggatccatccacgggcatcgtctccg accgcaccgtgaccgtcacgaaacacgacatgttttgcccggggatcagcatgga cggcaacggccagatcgtcgtcacgggcggcaatgacgccaagaagacgagcctc tatgacagtagcagcgacagttggatcccggggccggacatgcaggtggcacgcg ggtaccagtccagcgcgaccatgtcagacggccgtgtctttacaatcggcggctc atttagtggcggagtgtttgagaagaatggcgaagtctatagcccctcatccaaa acgtggacgtcacttccgaacgcgaaggtgaatcccatgttaaccgccgacaaac agggcctgtacatgagcgacaaccatgcgtggctgttcggctggaagaaggggag cgtctttcaggcgggcccgtcgaccgcaatgaattggtattacacgtcaggaagc ggggacgtgaaatcagccggcaagcgccagtcgaaccgcggcgtggcgccggacg caatgtgcggcaatgccgtgatgtatgacgcggtcaaaggcaagatcctgacatt tggcgggagtccggactacaccgacagtgacgcgacaaccaatgcccacattatt acccttggggagccggggacgagcccgaacacggtcttcgcgtccaatggcctct atttcgcgcgtacctttcatacgtcggtggtcctgccggacggatcaacctttat caccggcggacagcgccgtggcatccccttcgaagactcgacccccgtctttaca ccggagatttatgtgccggaacaggacacgttttataaacagaatccgaactcga ttgtacgcgcgtatcactccatcagccttcttctcccggacggacgtgtctttaa tggcggaggaggactgtgcggggactgcacgaccaatcattttgacgcgcagatc tttaccccgaattatctgtatgattcaaatgggaatctcgcgacccgtccgaaaa ttacccgtacatcaacccagtccgtcaaagtgggcggccgcattacgatcagtac cgacagcagcattaccaaagcgtcactgattcgttacggcaccgcaacccataca gtcaacacggaccagcgccgtattccgttaaccctgaccaataacggtggcaatt cgtatagcttccaggtaccgtcggactcgggcgtggcgctgccaggatactggat gctgtttgtgatgaatagcgcgggcgtcccgagcgtagcgagcacgatccgtgtg acccaggccgcagcttgataa 36 GOh1035 MGSSHHHHHHSSGLVPRGSHMGTASAPIGSAIPRNNWAVTCDSAQSGNECNKAID GNKDTFWHTFYGANGDPKPPHTYTIDMKTTQNVNGLSVLPRQDGNQNGWIGRHEV YLSSDGTNWGSPVASGSWFADSTTKYSNFETRPARYVRLVAVTEANGQPWTSIAE INVFQASSYTAPQPGLGRWGPTIDLPIVPAAAAIEPTSGRVLMWSSYRNDAYEGS PGGITLTSSWDPSTGIVSDRTVTVTKHDMFCPGISMDGNGQIVVTGGNDAKKTSL YDSSSDSWIPGPDMQVARGYQSSATMSDGRVFTIGGSFSGGVFEKNGEVYSPSSK TWTSLPNAKVNPMLTADKQGLYMSDNHAWLFGWKKGSVFQAGPSTAMNWYYTSGS GDVKSAGKRQSNRGVAPDAMCGNAVMYDAVKGKILTFGGSPDYTDSDATTNAHII TLGEPGTSPNTVFASNGLYFARTFHTSVVLPDGSTFITGGQRRGIPFEDSTPVFT PEIYVPEQDTFYKQNPNSIVRAYHSISLLLPDGRVFNGGGGLCGDCTTNHFDAQI FTPNYLYDSNGNLATRPKITRTSTQSVKVGGRITISTDSSITKASLIRYGTATHT VNTDQRRIPLTLTNNGGNSYSFQVPSDSGVALPGYWMLFVMNSAGVPSVASTIRV TQAAA 37 GOh1036 atgggcagcagccatcatcatcatcatcacagcagcggcctggtgccgcgcggca gccatatgggtaccgcctctgcccctatcggctcagccatcccgcgcaataactg ggccgtaacgtgcgacagcgcgcagagcggcaacgagtgcaataaagccatcgac ggcaataaagacaccttctggcacacgttttatggcgcaaatggcgacccgaagc caccgcatacctataccattgacatgaaaaccacccagaatgtgaacgggctgtc cgtgctgccgcgccaggacggcaatcagaacggatggatcggccgtcacgaggta tatttaagctccgacggcaccaactggggatccccggtcgcgtcgggcagctggt tcgccgacagcaccaccaagtattccaattttgaaacccgtcctgcacgctacgt gcgcttagtggccgtgacagaggcgaacggccagccatggacctcaatcgccgaa atcaatgtattccaagccagctcctataccgcgccgcagccaggacttgggcgtt ggggcccgaccatcgacctgcctatcgtacccgcagccgcggcgattgaaccaac gtcaggccgcgtactgatgtggagcagctaccgtaacgacgcggcggaaggcagc ccgggcggcatcactctgacgtcgagttgggatccatccacgggcatcgtctccg accgcaccgtgaccgtcacgaaacacgacatgttttgcccggggatcagcatgga cggcaacggccagatcgtcgtcacgggcggcaatgacgccaagaagacgagcctc tatgacagtagcagcgacagttggatcccggggccggacatgcaggtggcacgcg ggtaccagtccagcgcgaccatgtcagacggccgtgtctttacaatcggcggctc atttagtggcggagtgtttgagaagaatggcgaagtctatagcccctcatccaaa acgtggacgtcacttccgaacgcgaaggtgaatcccatgttaaccgccgacaaac agggcctgtacatgagcgacaaccatgcgtggctgttcggctggaagaaggggag cgtctttcaggcgggcccgtcgaccgcaatgaattggtattacacgtcaggaagc ggggacgtgaaatcagccggcaagcgccagtcgaaccgcggcgtggcgccggacg caatgtgcggcaatgccgtgatgtatgacgcggtcaaaggcaagatcctgacatt tggcgggagtccggactacaccgacagtgacgcgacaaccaatgcccacattatt acccttggggagccggggacgagcccgaacacggtcttcgcgtccaatggcctct atttcgcgcgtacctttcatacgtcggtggtcctgccggacggatcaacctttat caccggcggacagcgccgtggcatccccttcgaagactcgacccccgtctttaca ccggagatttatgtgccggaacaggacacgttttataaacagaatccgaactcga ttgtacgcgcgtatcactccatcagccttcttctcccggacggacgtgtctttaa tggcggaggaggactgtgcggggactgcacgaccaatcattttgacgcgcagatc tttaccccgaattatctgtatgattcaaatgggaatctcgcgacccgtccgaaaa ttacccgtacatcaacccagtccgtcaaagtgggcggccgcattacgatcagtac cgacagcagcattaccaaagcgtcactgattcgttacggcaccgcaacccataca gtcaacacggaccagcgccgtattccgttaaccctgaccaataacggtggcaatt cgtatagcttccaggtaccgtcggactcgggcgtggcgctgccaggatactggat gctgtttgtgatgaatagcgcgggcgtcccgagcgtagcgagcacgatccgtgtg acccaggccgcagcttgataa 38 GOh1036 MGSSHHHHHHSSGLVPRGSHMGTASAPIGSAIPRNNWAVTCDSAQSGNECNKAID GNKDTFWHTFYGANGDPKPPHTYTIDMKTTQNVNGLSVLPRQDGNQNGWIGRHEV YLSSDGTNWGSPVASGSWFADSTTKYSNFETRPARYVRLVAVTEANGQPWTSIAE INVFQASSYTAPQPGLGRWGPTIDLPIVPAAAAIEPTSGRVLMWSSYRNDAAEGS PGGITLTSSWDPSTGIVSDRTVTVTKHDMFCPGISMDGNGQIVVTGGNDAKKTSL YDSSSDSWIPGPDMQVARGYQSSATMSDGRVFTIGGSFSGGVFEKNGEVYSPSSK TWTSLPNAKVNPMLTADKQGLYMSDNHAWLFGWKKGSVFQAGPSTAMNWYYTSGS GDVKSAGKRQSNRGVAPDAMCGNAVMYDAVKGKILTFGGSPDYTDSDATTNAHII TLGEPGTSPNTVFASNGLYFARTFHTSVVLPDGSTFITGGQRRGIPFEDSTPVFT PEIYVPEQDTFYKQNPNSIVRAYHSISLLLPDGRVFNGGGGLCGDCTTNHFDAQI FTPNYLYDSNGNLATRPKITRTSTQSVKVGGRITISTDSSITKASLIRYGTATHT VNTDQRRIPLTLTNNGGNSYSFQVPSDSGVALPGYWMLFVMNSAGVPSVASTIRV TQAAA 39 GOh1037 atgggcagcagccatcatcatcatcatcacagcagcggcctggtgccgcgcggca gccatatgggtaccgcctctgcccctatcggctcagccatcccgcgcaataactg ggccgtaacgtgcgacagcgcgcagagcggcaacgagtgcaataaagccatcgac ggcaataaagacaccttctggcacacgttttatggcgcaaatggcgacccgaagc caccgcatacctataccattgacatgaaaaccacccagaatgtgaacgggctgtc cgtgctgccgcgccaggacggcaatcagaacggatggatcggccgtcacgaggta tatttaagctccgacggcaccaactggggatccccggtcgcgtcgggcagctggt tcgccgacagcaccaccaagtattccaattttgaaacccgtcctgcacgctacgt gcgcttagtggccgtgacagaggcgaacggccagccatggacctcaatcgccgaa atcaatgtattccaagccagctcctataccgcgccgcagccaggacttgggcgtt ggggcccgaccatcgacctgcctatcgtacccgcagccgcggcgattgaaccaac gtcaggccgcgtactgatgtggagcagctaccgtaacgacgcgtgtgaaggcagc ccgggggcatcactctgacgtcgagttgggatccatccacgggcatcgtctccga ccgcaccgtgaccgtcacgaaacacgacatgttttgcccggggatcagcatggac ggcaacggccagatcgtcgtcacgggcggcaatgacgccaagaagacgagcctct atgacagtagcagcgacagttggatcccggggccggacatgcaggtggcacgcgg gtaccagtccagcgcgaccatgtcagacggccgtgtctttacaatcggcggctca tttagtggcggagtgtttgagaagaatggcgaagtctatagcccctcatccaaaa cgtggacgtcacttccgaacgcgaaggtgaatcccatgttaaccgccgacaaaca gggcctgtacatgagcgacaaccatgcgtggctgttcggctggaagaaggggagc gtctttcaggcgggcccgtcgaccgcaatgaattggtattacacgtcaggaagcg gggacgtgaaatcagccggcaagcgccagtcgaaccgcggcgtggcgccggacgc aatgtgcggcaatgccgtgatgtatgacgcggtcaaaggcaagatcctgacattt ggcgggagtccggactacaccgacagtgacgcgacaaccaatgcccacattatta cccttggggagccggggacgagcccgaacacggtcttcgcgtccaatggcctcta tttcgcgcgtacctttcatacgtcggtggtcctgccggacggatcaacctttatc accggcggacagcgccgtggcatccccttcgaagactcgacccccgtctttacac cggagatttatgtgccggaacaggacacgttttataaacagaatccgaactcgat tgtacgcgcgtatcactccatcagccttcttctcccggacggacgtgtctttaat ggcggaggaggactgtgcggggactgcacgaccaatcattttgacgcgcagatct ttaccccgaattatctgtatgattcaaatgggaatctcgcgacccgtccgaaaat tacccgtacatcaacccagtccgtcaaagtgggcggccgcattacgatcagtacc gacagcagcattaccaaagcgtcactgattcgttacggcaccgcaacccatacag tcaacacggaccagcgccgtattccgttaaccctgaccaataacggtggcaattc gtatagcttccaggtaccgtcggactcgggcgtggcgctgccaggatactggatg ctgtttgtgatgaatagcgcgggcgtcccgagcgtagcgagcacgatccgtgtga cccaggccgcagcttgataa 40 GOh1037 MGSSHHHHHHSSGLVPRGSHMGTASAPIGSAIPRNNWAVTCDSAQSGNECNKAID GNKDTFWHTFYGANGDPKPPHTYTIDMKTTQNVNGLSVLPRQDGNQNGWIGRHEV YLSSDGTNWGSPVASGSWFADSTTKYSNFETRPARYVRLVAVTEANGQPWTSIAE INVFQASSYTAPQPGLGRWGPTIDLPIVPAAAAIEPTSGRVLMWSSYRNDACEGS PGGITLTSSWDPSTGIVSDRTVTVTKHDMFCPGISMDGNGQIVVTGGNDAKKTSL YDSSSDSWIPGPDMQVARGYQSSATMSDGRVFTIGGSFSGGVFEKNGEVYSPSSK TWTSLPNAKVNPMLTADKQGLYMSDNHAWLFGWKKGSVFQAGPSTAMNWYYTSGS GDVKSAGKRQSNRGVAPDAMCGNAVMYDAVKGKILTFGGSPDYTDSDATTNAHII TLGEPGTSPNTVFASNGLYFARTFHTSVVLPDGSTFITGGQRRGIPFEDSTPVFT PEIYVPEQDTFYKQNPNSIVRAYHSISLLLPDGRVFNGGGGLCGDCTTNHFDAQI FTPNYLYDSNGNLATRPKITRTSTQSVKVGGRITISTDSSITKASLIRYGTATHT VNTDQRRIPLTLTNNGGNSYSFQVPSDSGVALPGYWMLFVMNSAGVPSVASTIRV TQAAA 41 GOh1038 atgggcagcagccatcatcatcatcatcacagcagcggcctggtgccgcgcggca gccatatgggtaccgcctctgcccctatcggctcagccatcccgcgcaataactg ggccgtaacgtgcgacagcgcgcagagcggcaacgagtgcaataaagccatcgac ggcaataaagacaccttctggcacacgttttatggcgcaaatggcgacccgaagc caccgcatacctataccattgacatgaaaaccacccagaatgtgaacgggctgtc cgtgctgccgcgccaggacggcaatcagaacggatggatcggccgtcacgaggta tatttaagctccgacggcaccaactggggatccccggtcgcgtcgggcagctggt tcgccgacagcaccaccaagtattccaattttgaaacccgtcctgcacgctacgt gcgcttagtggccgtgacagaggcgaacggccagccatggacctcaatcgccgaa atcaatgtattccaagccagctcctataccgcgccgcagccaggacttgggcgtt ggggcccgaccatcgacctgcctatcgtacccgcagccgcggcgattgaaccaac gtcaggccgcgtactgatgtggagcagctaccgtaacgacgcggatgaaggcagc ccgggcggcatcactctgacgtcgagttgggatccatccacgggcatcgtctccg accgcaccgtgaccgtcacgaaacacgacatgttttgcccggggatcagcatgga cggcaacggccagatcgtcgtcacgggcggcaatgacgccaagaagacgagcctc tatgacagtagcagcgacagttggatcccggggccggacatgcaggtggcacgcg ggtaccagtccagcgcgaccatgtcagacggccgtgtctttacaatcggcggctc atttagtggcggagtgtttgagaagaatggcgaagtctatagcccctcatccaaa acgtggacgtcacttccgaacgcgaaggtgaatcccatgttaaccgccgacaaac agggcctgtacatgagcgacaaccatgcgtggctgttcggctggaagaaggggag cgtctttcaggcgggcccgtcgaccgcaatgaattggtattacacgtcaggaagc ggggacgtgaaatcagccggcaagcgccagtcgaaccgcggcgtggcgccggacg caatgtgcggcaatgccgtgatgtatgacgcggtcaaaggcaagatcctgacatt tggcgggagtccggactacaccgacagtgacgcgacaaccaatgcccacattatt acccttggggagccggggacgagcccgaacacggtcttcgcgtccaatggcctct atttcgcgcgtacctttcatacgtcggtggtcctgccggacggatcaacctttat caccggcggacagcgccgtggcatccccttcgaagactcgacccccgtctttaca ccggagatttatgtgccggaacaggacacgttttataaacagaatccgaactcga ttgtacgcgcgtatcactccatcagccttcttctcccggacggacgtgtctttaa tggcggaggaggactgtgcggggactgcacgaccaatcattttgacgcgcagatc tttaccccgaattatctgtatgattcaaatgggaatctcgcgacccgtccgaaaa ttacccgtacatcaacccagtccgtcaaagtgggcggccgcattacgatcagtac cgacagcagcattaccaaagcgtcactgattcgttacggcaccgcaacccataca gtcaacacggaccagcgccgtattccgttaaccctgaccaataacggtggcaatt cgtatagcttccaggtaccgtcggactcgggcgtggcgctgccaggatactggat gctgtttgtgatgaatagcgcgggcgtcccgagcgtagcgagcacgatccgtgtg acccaggccgcagcttgataa 42 GOh1038 MGSSHHHHHHSSGLVPRGSHMGTASAPIGSAIPRNNWAVTCDSAQSGNECNKAID GNKDTFWHTFYGANGDPKPPHTYTIDMKTTQNVNGLSVLPRQDGNQNGWIGRHEV YLSSDGTNWGSPVASGSWFADSTTKYSNFETRPARYVRLVAVTEANGQPWTSIAE INVFQASSYTAPQPGLGRWGPTIDLPIVPAAAAIEPTSGRVLMWSSYRNDADEGS PGGITLTSSWDPSTGIVSDRTVTVTKHDMFCPGISMDGNGQIVVTGGNDAKKTSL YDSSSDSWIPGPDMQVARGYQSSATMSDGRVFTIGGSFSGGVFEKNGEVYSPSSK TWTSLPNAKVNPMLTADKQGLYMSDNHAWLFGWKKGSVFQAGPSTAMNWYYTSGS GDVKSAGKRQSNRGVAPDAMCGNAVMYDAVKGKILTFGGSPDYTDSDATTNAHII TLGEPGTSPNTVFASNGLYFARTFHTSVVLPDGSTFITGGQRRGIPFEDSTPVFT PEIYVPEQDTFYKQNPNSIVRAYHSISLLLPDGRVFNGGGGLCGDCTTNHFDAQI FTPNYLYDSNGNLATRPKITRTSTQSVKVGGRITISTDSSITKASLIRYGTATHT VNTDQRRIPLTLTNNGGNSYSFQVPSDSGVALPGYWMLFVMNSAGVPSVASTIRV TQAAA 43 GOh1039 atgggcagcagccatcatcatcatcatcacagcagcggcctggtgccgcgcggca gccatatgggtaccgcctctgcccctatcggctcagccatcccgcgcaataactg ggccgtaacgtgcgacagcgcgcagagcggcaacgagtgcaataaagccatcgac ggcaataaagacaccttctggcacacgttttatggcgcaaatggcgacccgaagc caccgcatacctataccattgacatgaaaaccacccagaatgtgaacgggctgtc cgtgctgccgcgccaggacggcaatcagaacggatggatcggccgtcacgaggta tatttaagctccgacggcaccaactggggatccccggtcgcgtcgggcagctggt tcgccgacagcaccaccaagtattccaattttgaaacccgtcctgcacgctacgt gcgcttagtggccgtgacagaggcgaacggccagccatggacctcaatcgccgaa atcaatgtattccaagccagctcctataccgcgccgcagccaggacttgggcgtt ggggcccgaccatcgacctgcctatcgtacccgcagccgcggcgattgaaccaac gtcaggccgcgtactgatgtggagcagctaccgtaacgacgcgggtgaaggcagc ccgggcggcatcactctgacgtcgagttgggatccatccacgggcatcgtctccg accgcaccgtgaccgtcacgaaacacgacatgttttgcccggggatcagcatgga cggcaacggccagatcgtcgtcacgggcggcaatgacgccaagaagacgagcctc tatgacagtagcagcgacagttggatcccggggccggacatgcaggtggcacgcg ggtaccagtccagcgcgaccatgtcagacggccgtgtctttacaatcggcggctc atttagtggcggagtgtttgagaagaatggcgaagtctatagcccctcatccaaa acgtggacgtcacttccgaacgcgaaggtgaatcccatgttaaccgccgacaaac agggcctgtacatgagcgacaaccatgcgtggctgttcggctggaagaaggggag cgtctttcaggcgggcccgtcgaccgcaatgaattggtattacacgtcaggaagc ggggacgtgaaatcagccggcaagcgccagtcgaaccgcggcgtggcgccggacg caatgtgcggcaatgccgtgatgtatgacgcggtcaaaggcaagatcctgacatt tggcgggagtccggactacaccgacagtgacgcgacaaccaatgcccacattatt acccttggggagccggggacgagcccgaacacggtcttcgcgtccaatggcctct atttcgcgcgtacctttcatacgtcggtggtcctgccggacggatcaacctttat caccggcggacagcgccgtggcatccccttcgaagactcgacccccgtctttaca ccggagatttatgtgccggaacaggacacgttttataaacagaatccgaactcga ttgtacgcgcgtatcactccatcagccttcttctcccggacggacgtgtctttaa tggcggaggaggactgtgcggggactgcacgaccaatcattttgacgcgcagatc tttaccccgaattatctgtatgattcaaatgggaatctcgcgacccgtccgaaaa ttacccgtacatcaacccagtccgtcaaagtgggcggccgcattacgatcagtac cgacagcagcattaccaaagcgtcactgattcgttacggcaccgcaacccataca gtcaacacggaccagcgccgtattccgttaaccctgaccaataacggtggcaatt cgtatagcttccaggtaccgtcggactcgggcgtggcgctgccaggatactggat gctgtttgtgatgaatagcgcgggcgtcccgagcgtagcgagcacgatccgtgtg acccaggccgcagcttgataa 44 GOh1039 MGSSHHHHHHSSGLVPRGSHMGTASAPIGSAIPRNNWAVTCDSAQSGNECNKAID GNKDTFWHTFYGANGDPKPPHTYTIDMKTTQNVNGLSVLPRQDGNQNGWIGRHEV YLSSDGTNWGSPVASGSWFADSTTKYSNFETRPARYVRLVAVTEANGQPWTSIAE INVFQASSYTAPQPGLGRWGPTIDLPIVPAAAAIEPTSGRVLMWSSYRNDAGEGS PGGITLTSSWDPSTGIVSDRTVTVTKHDMFCPGISMDGNGQIVVTGGNDAKKTSL YDSSSDSWIPGPDMQVARGYQSSATMSDGRVFTIGGSFSGGVFEKNGEVYSPSSK TWTSLPNAKVNPMLTADKQGLYMSDNHAWLFGWKKGSVFQAGPSTAMNWYYTSGS GDVKSAGKRQSNRGVAPDAMCGNAVMYDAVKGKILTFGGSPDYTDSDATTNAHII TLGEPGTSPNTVFASNGLYFARTFHTSVVLPDGSTFITGGQRRGIPFEDSTPVFT PEIYVPEQDTFYKQNPNSIVRAYHSISLLLPDGRVFNGGGGLCGDCTTNHFDAQI FTPNYLYDSNGNLATRPKITRTSTQSVKVGGRITISTDSSITKASLIRYGTATHT VNTDQRRIPLTLTNNGGNSYSFQVPSDSGVALPGYWMLFVMNSAGVPSVASTIRV TQAAA 45 GOh1040 atgggcagcagccatcatcatcatcatcacagcagcggcctggtgccgcgcggca gccatatgggtaccgcctctgcccctatcggctcagccatcccgcgcaataactg ggccgtaacgtgcgacagcgcgcagagcggcaacgagtgcaataaagccatcgac ggcaataaagacaccttctggcacacgttttatggcgcaaatggcgacccgaagc caccgcatacctataccattgacatgaaaaccacccagaatgtgaacgggctgtc cgtgctgccgcgccaggacggcaatcagaacggatggatcggccgtcacgaggta tatttaagctccgacggcaccaactggggatccccggtcgcgtcgggcagctggt tcgccgacagcaccaccaagtattccaattttgaaacccgtcctgcacgctacgt gcgcttagtggccgtgacagaggcgaacggccagccatggacctcaatcgccgaa atcaatgtattccaagccagctcctataccgcgccgcagccaggacttgggcgtt ggggcccgaccatcgacctgcctatcgtacccgcagccgcggcgattgaaccaac gtcaggccgcgtactgatgtggagcagctaccgtaacgacgcgcatgaaggcagc ccgggcggcatcactctgacgtcgagttgggatccatccacgggcatcgtctccg accgcaccgtgaccgtcacgaaacacgacatgttttgcccggggatcagcatgga cggcaacggccagatcgtcgtcacgggcggcaatgacgccaagaagacgagcctc tatgacagtagcagcgacagttggatcccggggccggacatgcaggtggcacgcg ggtaccagtccagcgcgaccatgtcagacggccgtgtctttacaatcggcggctc atttagtggcggagtgtttgagaagaatggcgaagtctatagcccctcatccaaa acgtggacgtcacttccgaacgcgaaggtgaatcccatgttaaccgccgacaaac agggcctgtacatgagcgacaaccatgcgtggctgttcggctggaagaaggggag cgtctttcaggcgggcccgtcgaccgcaatgaattggtattacacgtcaggaagc ggggacgtgaaatcagccggcaagcgccagtcgaaccgcggcgtggcgccggacg caatgtgcggcaatgccgtgatgtatgacgcggtcaaaggcaagatcctgacatt tggcgggagtccggactacaccgacagtgacgcgacaaccaatgcccacattatt acccttggggagccggggacgagcccgaacacggtcttcgcgtccaatggcctct atttcgcgcgtacctttcatacgtcggtggtcctgccggacggatcaacctttat caccggcggacagcgccgtggcatccccttcgaagactcgacccccgtctttaca ccggagatttatgtgccggaacaggacacgttttataaacagaatccgaactcga ttgtacgcgcgtatcactccatcagccttcttctcccggacggacgtgtctttaa tggcggaggaggactgtgcggggactgcacgaccaatcattttgacgcgcagatc tttaccccgaattatctgtatgattcaaatgggaatctcgcgacccgtccgaaaa ttacccgtacatcaacccagtccgtcaaagtgggcggccgcattacgatcagtac cgacagcagcattaccaaagcgtcactgattcgttacggcaccgcaacccataca gtcaacacggaccagcgccgtattccgttaaccctgaccaataacggtggcaatt cgtatagcttccaggtaccgtcggactcgggcgtggcgctgccaggatactggat gctgtttgtgatgaatagcgcgggcgtcccgagcgtagcgagcacgatccgtgtg acccaggccgcagcttgataa 46 GOh1040 MGSSHHHHHHSSGLVPRGSHMGTASAPIGSAIPRNNWAVTCDSAQSGNECNKAID GNKDTFWHTFYGANGDPKPPHTYTIDMKTTQNVNGLSVLPRQDGNQNGWIGRHEV YLSSDGTNWGSPVASGSWFADSTTKYSNFETRPARYVRLVAVTEANGQPWTSIAE INVFQASSYTAPQPGLGRWGPTIDLPIVPAAAAIEPTSGRVLMWSSYRNDAHEGS PGGITLTSSWDPSTGIVSDRTVTVTKHDMFCPGISMDGNGQIVVTGGNDAKKTSL YDSSSDSWIPGPDMQVARGYQSSATMSDGRVFTIGGSFSGGVFEKNGEVYSPSSK TWTSLPNAKVNPMLTADKQGLYMSDNHAWLFGWKKGSVFQAGPSTAMNWYYTSGS GDVKSAGKRQSNRGVAPDAMCGNAVMYDAVKGKILTFGGSPDYTDSDATTNAHII TLGEPGTSPNTVFASNGLYFARTFHTSVVLPDGSTFITGGQRRGIPFEDSTPVFT PEIYVPEQDTFYKQNPNSIVRAYHSISLLLPDGRVFNGGGGLCGDCTTNHFDAQI FTPNYLYDSNGNLATRPKITRTSTQSVKVGGRITISTDSSITKASLIRYGTATHT VNTDQRRIPLTLTNNGGNSYSFQVPSDSGVALPGYWMLFVMNSAGVPSVASTIRV TQAAA 47 GOh1041 atgggcagcagccatcatcatcatcatcacagcagcggcctggtgccgcgcggca gccatatgggtaccgcctctgcccctatcggctcagccatcccgcgcaataactg ggccgtaacgtgcgacagcgcgcagagcggcaacgagtgcaataaagccatcgac ggcaataaagacaccttctggcacacgttttatggcgcaaatggcgacccgaagc caccgcatacctataccattgacatgaaaaccacccagaatgtgaacgggctgtc cgtgctgccgcgccaggacggcaatcagaacggatggatcggccgtcacgaggta tatttaagctccgacggcaccaactggggatccccggtcgcgtcgggcagctggt tcgccgacagcaccaccaagtattccaattttgaaacccgtcctgcacgctacgt gcgcttagtggccgtgacagaggcgaacggccagccatggacctcaatcgccgaa atcaatgtattccaagccagctcctataccgcgccgcagccaggacttgggcgtt ggggcccgaccatcgacctgcctatcgtacccgcagccgcggcgattgaaccaac gtcaggccgcgtactgatgtggagcagctaccgtaacgacgcgaaagaaggcagc ccgggcggcatcactctgacgtcgagttgggatccatccacgggcatcgtctccg accgcaccgtgaccgtcacgaaacacgacatgttttgcccggggatcagcatgga cggcaacggccagatcgtcgtcacgggcggcaatgacgccaagaagacgagcctc tatgacagtagcagcgacagttggatcccggggccggacatgcaggtggcacgcg ggtaccagtccagcgcgaccatgtcagacggccgtgtctttacaatcggcggctc atttagtggcggagtgtttgagaagaatggcgaagtctatagcccctcatccaaa acgtggacgtcacttccgaacgcgaaggtgaatcccatgttaaccgccgacaaac agggcctgtacatgagcgacaaccatgcgtggctgttcggctggaagaaggggag cgtctttcagggggcccgtcgaccgcaatgaattggtattacacgtcaggaagcg gggacgtgaaatcagccggcaagcgccagtcgaaccgcggcgtggcgccggacgc aatgtgcggcaatgccgtgatgtatgacgcggtcaaaggcaagatcctgacattt ggcgggagtccggactacaccgacagtgacgcgacaaccaatgcccacattatta cccttggggagccggggacgagcccgaacacggtcttcgcgtccaatggcctcta tttcgcgcgtacctttcatacgtcggtggtcctgccggacggatcaacctttatc accggcggacagcgccgtggcatccccttcgaagactcgacccccgtctttacac cggagatttatgtgccggaacaggacacgttttataaacagaatccgaactcgat tgtacgcgcgtatcactccatcagccttcttctcccggacggacgtgtctttaat ggcggaggaggactgtgcggggactgcacgaccaatcattttgacgcgcagatct ttaccccgaattatctgtatgattcaaatgggaatctcgcgacccgtccgaaaat tacccgtacatcaacccagtccgtcaaagtgggcggccgcattacgatcagtacc gacagcagcattaccaaagcgtcactgattcgttacggcaccgcaacccatacag tcaacacggaccagcgccgtattccgttaaccctgaccaataacggtggcaattc gtatagcttccaggtaccgtcggactcgggcgtggcgctgccaggatactggatg ctgtttgtgatgaatagcgcgggcgtcccgagcgtagcgagcacgatccgtgtga cccaggccgcagcttgataa 48 GOh1041 MGSSHHHHHHSSGLVPRGSHMGTASAPIGSAIPRNNWAVTCDSAQSGNECNKAID GNKDTFWHTFYGANGDPKPPHTYTIDMKTTQNVNGLSVLPRQDGNQNGWIGRHEV YLSSDGTNWGSPVASGSWFADSTTKYSNFETRPARYVRLVAVTEANGQPWTSIAE INVFQASSYTAPQPGLGRWGPTIDLPIVPAAAAIEPTSGRVLMWSSYRNDAKEGS PGGITLTSSWDPSTGIVSDRTVTVTKHDMFCPGISMDGNGQIVVTGGNDAKKTSL YDSSSDSWIPGPDMQVARGYQSSATMSDGRVFTIGGSFSGGVFEKNGEVYSPSSK TWTSLPNAKVNPMLTADKQGLYMSDNHAWLFGWKKGSVFQAGPSTAMNWYYTSGS GDVKSAGKRQSNRGVAPDAMCGNAVMYDAVKGKILTFGGSPDYTDSDATTNAHII TLGEPGTSPNTVFASNGLYFARTFHTSVVLPDGSTFITGGQRRGIPFEDSTPVFT PEIYVPEQDTFYKQNPNSIVRAYHSISLLLPDGRVFNGGGGLCGDCTTNHFDAQI FTPNYLYDSNGNLATRPKITRTSTQSVKVGGRITISTDSSITKASLIRYGTATHT VNTDQRRIPLTLTNNGGNSYSFQVPSDSGVALPGYWMLFVMNSAGVPSVASTIRV TQAAA 49 GOh1042 atgggcagcagccatcatcatcatcatcacagcagcggcctggtgccgcgcggca gccatatgggtaccgcctctgcccctatcggctcagccatcccgcgcaataactg ggccgtaacgtgcgacagcgcgcagagcggcaacgagtgcaataaagccatcgac ggcaataaagacaccttctggcacacgttttatggcgcaaatggcgacccgaagc caccgcatacctataccattgacatgaaaaccacccagaatgtgaacgggctgtc cgtgctgccgcgccaggacggcaatcagaacggatggatcggccgtcacgaggta tatttaagctccgacggcaccaactggggatccccggtcgcgtcgggcagctggt tcgccgacagcaccaccaagtattccaattttgaaacccgtcctgcacgctacgt gcgcttagtggccgtgacagaggcgaacggccagccatggacctcaatcgccgaa atcaatgtattccaagccagctcctataccgcgccgcagccaggacttgggcgtt ggggcccgaccatcgacctgcctatcgtacccgcagccgcggcgattgaaccaac gtcaggccgcgtactgatgtggagcagctaccgtaacgacgcgatggaaggcagc ccgggcggcatcactctgacgtcgagttgggatccatccacgggcatcgtctccg accgcaccgtgaccgtcacgaaacacgacatgttttgcccggggatcagcatgga cggcaacggccagatcgtcgtcacgggcggcaatgacgccaagaagacgagcctc tatgacagtagcagcgacagttggatcccggggccggacatgcaggtggcacgcg ggtaccagtccagcgcgaccatgtcagacggccgtgtctttacaatcggcggctc atttagtggcggagtgtttgagaagaatggcgaagtctatagcccctcatccaaa acgtggacgtcacttccgaacgcgaaggtgaatcccatgttaaccgccgacaaac agggcctgtacatgagcgacaaccatgcgtggctgttcggctggaagaaggggag cgtctttcaggcgggcccgtcgaccgcaatgaattggtattacacgtcaggaagc ggggacgtgaaatcagccggcaagcgccagtcgaaccgcggcgtggcgccggacg caatgtgcggcaatgccgtgatgtatgacgcggtcaaaggcaagatcctgacatt tggcgggagtccggactacaccgacagtgacgcgacaaccaatgcccacattatt acccttggggagccggggacgagcccgaacacggtcttcgcgtccaatggcctct atttcgcgcgtacctttcatacgtcggtggtcctgccggacggatcaacctttat caccggcggacagcgccgtggcatccccttcgaagactcgacccccgtctttaca ccggagatttatgtgccggaacaggacacgttttataaacagaatccgaactcga ttgtacgcgcgtatcactccatcagccttcttctcccggacggacgtgtctttaa tggcggaggaggactgtgcggggactgcacgaccaatcattttgacgcgcagatc tttaccccgaattatctgtatgattcaaatgggaatctcgcgacccgtccgaaaa ttacccgtacatcaacccagtccgtcaaagtgggcggccgcattacgatcagtac cgacagcagcattaccaaagcgtcactgattcgttacggcaccgcaacccataca gtcaacacggaccagcgccgtattccgttaaccctgaccaataacggtggcaatt cgtatagcttccaggtaccgtcggactcgggcgtggcgctgccaggatactggat gctgtttgtgatgaatagcgcgggcgtcccgagcgtagcgagcacgatccgtgtg acccaggccgcagcttgataa 50 GOh1042 MGSSHHHHHHSSGLVPRGSHMGTASAPIGSAIPRNNWAVTCDSAQSGNECNKAID GNKDTFWHTFYGANGDPKPPHTYTIDMKTTQNVNGLSVLPRQDGNQNGWIGRHEV YLSSDGTNWGSPVASGSWFADSTTKYSNFETRPARYVRLVAVTEANGQPWTSIAE INVFQASSYTAPQPGLGRWGPTIDLPIVPAAAAIEPTSGRVLMWSSYRNDAMEGS PGGITLTSSWDPSTGIVSDRTVTVTKHDMFCPGISMDGNGQIVVTGGNDAKKTSL YDSSSDSWIPGPDMQVARGYQSSATMSDGRVFTIGGSFSGGVFEKNGEVYSPSSK TWTSLPNAKVNPMLTADKQGLYMSDNHAWLFGWKKGSVFQAGPSTAMNWYYTSGS GDVKSAGKRQSNRGVAPDAMCGNAVMYDAVKGKILTFGGSPDYTDSDATTNAHII TLGEPGTSPNTVFASNGLYFARTFHTSVVLPDGSTFITGGQRRGIPFEDSTPVFT PEIYVPEQDTFYKQNPNSIVRAYHSISLLLPDGRVFNGGGGLCGDCTTNHFDAQI FTPNYLYDSNGNLATRPKITRTSTQSVKVGGRITISTDSSITKASLIRYGTATHT VNTDQRRIPLTLTNNGGNSYSFQVPSDSGVALPGYWMLFVMNSAGVPSVASTIRV TQAAA 51 GOh1043 atgggcagcagccatcatcatcatcatcacagcagcggcctggtgccgcgcggca gccatatgggtaccgcctctgcccctatcggctcagccatcccgcgcaataactg ggccgtaacgtgcgacagcgcgcagagcggcaacgagtgcaataaagccatcgac ggcaataaagacaccttctggcacacgttttatggcgcaaatggcgacccgaagc caccgcatacctataccattgacatgaaaaccacccagaatgtgaacgggctgtc cgtgctgccgcgccaggacggcaatcagaacggatggatcggccgtcacgaggta tatttaagctccgacggcaccaactggggatccccggtcgcgtcgggcagctggt tcgccgacagcaccaccaagtattccaattttgaaacccgtcctgcacgctacgt gcgcttagtggccgtgacagaggcgaacggccagccatggacctcaatcgccgaa atcaatgtattccaagccagctcctataccgcgccgcagccaggacttgggcgtt ggggcccgaccatcgacctgcctatcgtacccgcagccgcggcgattgaaccaac gtcaggccgcgtactgatgtggagcagctaccgtaacgacgcgcgtgaaggcagc ccgggcggcatcactctgacgtcgagttgggatccatccacgggcatcgtctccg accgcaccgtgaccgtcacgaaacacgacatgttttgcccggggatcagcatgga cggcaacggccagatcgtcgtcacgggcggcaatgacgccaagaagacgagcctc tatgacagtagcagcgacagttggatcccggggccggacatgcaggtggcacgcg ggtaccagtccagcgcgaccatgtcagacggccgtgtctttacaatcggcggctc atttagtggcggagtgtttgagaagaatggcgaagtctatagcccctcatccaaa acgtggacgtcacttccgaacgcgaaggtgaatcccatgttaaccgccgacaaac agggcctgtacatgagcgacaaccatgcgtggctgttcggctggaagaaggggag cgtctttcaggcgggcccgtcgaccgcaatgaattggtattacacgtcaggaagc ggggacgtgaaatcagccggcaagcgccagtcgaaccgcggcgtggcgccggacg caatgtgcggcaatgccgtgatgtatgacgcggtcaaaggcaagatcctgacatt tggcgggagtccggactacaccgacagtgacgcgacaaccaatgcccacattatt acccttggggagccggggacgagcccgaacacggtcttcgcgtccaatggcctct atttcgcgcgtacctttcatacgtcggtggtcctgccggacggatcaacctttat caccggcggacagcgccgtggcatccccttcgaagactcgacccccgtctttaca ccggagatttatgtgccggaacaggacacgttttataaacagaatccgaactcga ttgtacgcgcgtatcactccatcagccttcttctcccggacggacgtgtctttaa tggcggaggaggactgtgcggggactgcacgaccaatcattttgacgcgcagatc tttaccccgaattatctgtatgattcaaatgggaatctcgcgacccgtccgaaaa ttacccgtacatcaacccagtccgtcaaagtgggcggccgcattacgatcagtac cgacagcagcattaccaaagcgtcactgattcgttacggcaccgcaacccataca gtcaacacggaccagcgccgtattccgttaaccctgaccaataacggtggcaatt cgtatagcttccaggtaccgtcggactcgggcgtggcgctgccaggatactggat gctgtttgtgatgaatagcgcgggcgtcccgagcgtagcgagcacgatccgtgtg acccaggccgcagcttgataa 52 GOh1043 MGSSHHHHHHSSGLVPRGSHMGTASAPIGSAIPRNNWAVTCDSAQSGNECNKAID GNKDTFWHTFYGANGDPKPPHTYTIDMKTTQNVNGLSVLPRQDGNQNGWIGRHEV YLSSDGTNWGSPVASGSWFADSTTKYSNFETRPARYVRLVAVTEANGQPWTSIAE INVFQASSYTAPQPGLGRWGPTIDLPIVPAAAAIEPTSGRVLMWSSYRNDAREGS PGGITLTSSWDPSTGIVSDRTVTVTKHDMFCPGISMDGNGQIVVTGGNDAKKTSL YDSSSDSWIPGPDMQVARGYQSSATMSDGRVFTIGGSFSGGVFEKNGEVYSPSSK TWTSLPNAKVNPMLTADKQGLYMSDNHAWLFGWKKGSVFQAGPSTAMNWYYTSGS GDVKSAGKRQSNRGVAPDAMCGNAVMYDAVKGKILTFGGSPDYTDSDATTNAHII TLGEPGTSPNTVFASNGLYFARTFHTSVVLPDGSTFITGGQRRGIPFEDSTPVFT PEIYVPEQDTFYKQNPNSIVRAYHSISLLLPDGRVFNGGGGLCGDCTTNHFDAQI FTPNYLYDSNGNLATRPKITRTSTQSVKVGGRITISTDSSITKASLIRYGTATHT VNTDQRRIPLTLTNNGGNSYSFQVPSDSGVALPGYWMLFVMNSAGVPSVASTIRV TQAAA 53 GOh1045 atgggcagcagccatcatcatcatcatcacagcagcggcctggtgccgcgcggca gccatatgggtaccgcctctgcccctatcggctcagccatcccgcgcaataactg ggccgtaacgtgcgacagcgcgcagagcggcaacgagtgcaataaagccatcgac ggcaataaagacaccttctggcacacgttttatggcgcaaatggcgacccgaagc caccgcatacctataccattgacatgaaaaccacccagaatgtgaacgggctgtc cgtgctgccgcgccaggacggcaatcagaacggatggatcggccgtcacgaggta tatttaagctccgacggcaccaactggggatccccggtcgcgtcgggcagctggt tcgccgacagcaccaccaagtattccaattttgaaacccgtcctgcacgctacgt gcgcttagtggccgtgacagaggcgaacggccagccatggacctcaatcgccgaa atcaatgtattccaagccagctcctataccgcgccgcagccaggacttgggcgtt ggggcccgaccatcgacctgcctatcgtacccgcagccgcggcgattgaaccaac gtcaggccgcgtactgatgtggagcagctaccgtaacgacgcgccacctggcagc ccgggcggcatcactctgacgtcgagttgggatccatccacgggcatcgtctccg accgcaccgtgaccgtcacgaaacacgacatgttttgcccggggatcagcatgga cggcaacggccagatcgtcgtcacgggcggcaatgacgccaagaagacgagcctc tatgacagtagcagcgacagttggatcccggggccggacatgcaggtggcacgcg ggtaccagtccagcgcgaccatgtcagacggccgtgtctttacaatcggcggctc atttagtggcggagtgtttgagaagaatggcgaagtctatagcccctcatccaaa acgtggacgtcacttccgaacgcgaaggtgaatcccatgttaaccgccgacaaac agggcctgtacatgagcgacaaccatgcgtggctgttcggctggaagaaggggag cgtctttcaggcgggcccgtcgaccgcaatgaattggtattacacgtcaggaagc ggggacgtgaaatcagccggcaagcgccagtcgaaccgcggcgtggcgccggacg caatgtgcggcaatgccgtgatgtatgacgcggtcaaaggcaagatcctgacatt tggcgggagtccggactacaccgacagtgacgcgacaaccaatgcccacattatt acccttggggagccggggacgagcccgaacacggtcttcgcgtccaatggcctct atttcgcgcgtacctttcatacgtcggtggtcctgccggacggatcaacctttat caccggcggacagcgccgtggcatccccttcgaagactcgacccccgtctttaca ccggagatttatgtgccggaacaggacacgttttataaacagaatccgaactcga ttgtacgcgcgtatcactccatcagccttcttctcccggacggacgtgtctttaa tggcggaggaggactgtgcggggactgcacgaccaatcattttgacgcgcagatc tttaccccgaattatctgtatgattcaaatgggaatctcgcgacccgtccgaaaa ttacccgtacatcaacccagtccgtcaaagtgggcggccgcattacgatcagtac cgacagcagcattaccaaagcgtcactgattcgttacggcaccgcaacccataca gtcaacacggaccagcgccgtattccgttaaccctgaccaataacggtggcaatt cgtatagcttccaggtaccgtcggactcgggcgtggcgctgccaggatactggat gctgtttgtgatgaatagcgcgggcgtcccgagcgtagcgagcacgatccgtgtg acccaggccgcagcttgataa 54 GOh1045 MGSSHHHHHHSSGLVPRGSHMGTASAPIGSAIPRNNWAVTCDSAQSGNECNKAID GNKDTFWHTFYGANGDPKPPHTYTIDMKTTQNVNGLSVLPRQDGNQNGWIGRHEV YLSSDGTNWGSPVASGSWFADSTTKYSNFETRPARYVRLVAVTEANGQPWTSIAE INVFQASSYTAPQPGLGRWGPTIDLPIVPAAAAIEPTSGRVLMWSSYRNDAPPGS PGGITLTSSWDPSTGIVSDRTVTVTKHDMFCPGISMDGNGQIVVTGGNDAKKTSL YDSSSDSWIPGPDMQVARGYQSSATMSDGRVFTIGGSFSGGVFEKNGEVYSPSSK TWTSLPNAKVNPMLTADKQGLYMSDNHAWLFGWKKGSVFQAGPSTAMNWYYTSGS GDVKSAGKRQSNRGVAPDAMCGNAVMYDAVKGKILTFGGSPDYTDSDATTNAHII TLGEPGTSPNTVFASNGLYFARTFHTSVVLPDGSTFITGGQRRGIPFEDSTPVFT PEIYVPEQDTFYKQNPNSIVRAYHSISLLLPDGRVFNGGGGLCGDCTTNHFDAQI FTPNYLYDSNGNLATRPKITRTSTQSVKVGGRITISTDSSITKASLIRYGTATHT VNTDQRRIPLTLTNNGGNSYSFQVPSDSGVALPGYWMLFVMNSAGVPSVASTIRV TQAAA 55 GOh1046 atgggcagcagccatcatcatcatcatcacagcagcggcctggtgccgcgcggca gccatatgggtaccgcctctgcccctatcggctcagccatcccgcgcaataactg ggccgtaacgtgcgacagcgcgcagagcggcaacgagtgcaataaagccatcgac ggcaataaagacaccttctggcacacgttttatggcgcaaatggcgacccgaagc caccgcatacctataccattgacatgaaaaccacccagaatgtgaacgggctgtc cgtgctgccgcgccaggacggcaatcagaacggatggatcggccgtcacgaggta tatttaagctccgacggcaccaactggggatccccggtcgcgtcgggcagctggt tcgccgacagcaccaccaagtattccaattttgaaacccgtcctgcacgctacgt gcgcttagtggccgtgacagaggcgaacggccagccatggacctcaatcgccgaa atcaatgtattccaagccagctcctataccgcgccgcagccaggacttgggcgtt ggggcccgaccatcgacctgcctatcgtacccgcagccgcggcgattgaaccaac gtcaggccgcgtactgatgtggagcagctaccgtaacgacgcgccggaaggcagc ccgggcggcatcactctgacgtcgagttgggatccatccacgggcatcgtctccg accgcaccgtgaccgtcacgaaacacgacatgttttgcccggggatcagcatgga cggcaacggccagatcgtcgtcacgggcggcaatgacgccaagaagacgagcctc tatgacagtagcagcgacagttggatcccggggccggacatgcaggtggcacgcg ggtaccagtccagcgcgaccatgtcagacggccgtgtctttacaatcggcggctc atttagtggcggagtgtttgagaagaatggcgaagtctatagcccctcatccaaa acgtggacgtcacttccgaacgcgaaggtgaatcccatgttaaccgccgacaaac agggcctgtacatgagcgacaaccatgcgtggctgttcggctggaagaaggggag cgtctttcaggcgggcccgtcgaccgcaatgaattggtattacacgtcaggaagc ggggacgtgaaatcagccggcaagcgccagtcgaaccgcggcgtggcgccggacg caatgtgcggcaatgccgtgatgtatgacgcggtcaaaggcaagatcctgacatt tggcgggagtccggactacaccgacagtgacgcgacaaccaatgcccacattatt acccttggggagccggggacgagcccgaacacggtcttcgcgtccaatggcctct atttcgcgcgtacctttcatacgtcggtggtcctgccggacggatcaacctttat caccggcggacagcgccgtggcatccccttcgaagactcgacccccgtctttaca ccggagatttatgtgccggaacaggacacgttttataaacagaatccgaactcga ttgtacgcgcgtatcactccatcagccttcttctcccggacggacgtgtctttaa tggcggaggaggagggtgcggggactgcacgaccaatcattttgacgcgcagatc tttaccccgaattatctgtatgattcaaatgggaatctcgcgacccgtccgaaaa ttacccgtacatcaacccagtccgtcaaagtgggcggccgcattacgatcagtac cgacagcagcattaccaaagcgtcactgattcgttacggcaccgcaacccataca gtcaacacggaccagcgccgtattccgttaaccctgaccaataacggtggcaatt cgtatagcttccaggtaccgtcggactcgggcgtggcgctgccaggatactggat gctgtttgtgatgaatagcgcgggcgtcccgagcgtagcgagcacgatccgtgtg acccaggccgcagcttgataa 56 GOh1046 MGSSHHHHHHSSGLVPRGSHMGTASAPIGSAIPRNNWAVTCDSAQSGNECNKAID GNKDTFWHTFYGANGDPKPPHTYTIDMKTTQNVNGLSVLPRQDGNQNGWIGRHEV YLSSDGTNWGSPVASGSWFADSTTKYSNFETRPARYVRLVAVTEANGQPWTSIAE INVFQASSYTAPQPGLGRWGPTIDLPIVPAAAAIEPTSGRVLMWSSYRNDAPEGS PGGITLTSSWDPSTGIVSDRTVTVTKHDMFCPGISMDGNGQIVVTGGNDAKKTSL YDSSSDSWIPGPDMQVARGYQSSATMSDGRVFTIGGSFSGGVFEKNGEVYSPSSK TWTSLPNAKVNPMLTADKQGLYMSDNHAWLFGWKKGSVFQAGPSTAMNWYYTSGS GDVKSAGKRQSNRGVAPDAMCGNAVMYDAVKGKILTFGGSPDYTDSDATTNAHII TLGEPGTSPNTVFASNGLYFARTFHTSVVLPDGSTFITGGQRRGIPFEDSTPVFT PEIYVPEQDTFYKQNPNSIVRAYHSISLLLPDGRVFNGGGGGCGDCTTNHFDAQI FTPNYLYDSNGNLATRPKITRTSTQSVKVGGRITISTDSSITKASLIRYGTATHT VNTDQRRIPLTLTNNGGNSYSFQVPSDSGVALPGYWMLFVMNSAGVPSVASTIRV TQAAA 57 GOh1047 atgggcagcagccatcatcatcatcatcacagcagcggcctggtgccgcgcggca gccatatgggtaccgcctctgcccctatcggctcagccatcccgcgcaataactg ggccgtaacgtgcgacagcgcgcagagcggcaacgagtgcaataaagccatcgac ggcaataaagacaccttctggcacacgttttatggcgcaaatggcgacccgaagc caccgcatacctataccattgacatgaaaaccacccagaatgtgaacgggctgtc cgtgctgccgcgccaggacggcaatcagaacggatggatcggccgtcacgaggta tatttaagctccgacggcaccaactggggatccccggtcgcgtcgggcagctggt tcgccgacagcaccaccaagtattccaattttgaaacccgtcctgcacgctacgt gcgcttagtggccgtgacagaggcgaacggccagccatggacctcaatcgccgaa atcaatgtattccaagccagctcctataccgcgccgcagccaggacttgggcgtt ggggcccgaccatcgacctgcctatcgtacccgcagccgcggcgattgaaccaac gtcaggccgcgtactgatgtggagcagctaccgtaacgacgcgccgccaggcagc ccgggggcatcactctgacgtcgagttgggatccatccacgggcatcgtctccga ccgcaccgtgaccgtcacgaaacacgacatgttttgcccggggatcagcatggac ggcaacggccagatcgtcgtcacgggcggcaatgacgccaagaagacgagcctct atgacagtagcagcgacagttggatcccggggccggacatgcaggtggcacgcgg gtaccagtccagcgcgaccatgtcagacggccgtgtctttacaatcggcggctca tttagtggcggagtgtttgagaagaatggcgaagtctatagcccctcatccaaaa cgtggacgtcacttccgaacgcgaaggtgaatcccatgttaaccgccgacaaaca gggcctgtacatgagcgacaaccatgcgtggctgttcggctggaagaaggggagc gtctttcaggcgggcccgtcgaccgcaatgaattggtattacacgtcaggaagcg gggacgtgaaatcagccggcaagcgccagtcgaaccgcggcgtggcgccggacgc aatgtgcggcaatgccgtgatgtatgacgcggtcaaaggcaagatcctgacattt ggcgggagtccggactacaccgacagtgacgcgacaaccaatgcccacattatta cccttggggagccggggacgagcccgaacacggtcttcgcgtccaatggcctcta tttcgcgcgtacctttcatacgtcggtggtcctgccggacggatcaacctttatc accggggacagcgccgtggcatccccttcgaagactcgacccccgtctttacacc ggagatttatgtgccggaacaggacacgttttataaacagaatccgaactcgatt gtacgcgcgtatcactccatcagccttcttctcccggacggacgtgtctttaatg gcggaggaggagggtgcggggactgcacgaccaatcattttgacgcgcagatctt taccccgaattatctgtatgattcaaatgggaatctcgcgacccgtccgaaaatt acccgtacatcaacccagtccgtcaaagtgggcggccgcattacgatcagtaccg acagcagcattaccaaagcgtcactgattcgttacggcaccgcaacccatacagt caacacggaccagcgccgtattccgttaaccctgaccaataacggtggcaattcg tatagcttccaggtaccgtcggactcgggcgtggcgctgccaggatactggatgc tgtttgtgatgaatagcgcgggcgtcccgagcgtagcgagcacgatccgtgtgac ccaggccgcagcttgataa 58 GOh1047 MGSSHHHHHHSSGLVPRGSHMGTASAPIGSAIPRNNWAVTCDSAQSGNECNKAID GNKDTFWHTFYGANGDPKPPHTYTIDMKTTQNVNGLSVLPRQDGNQNGWIGRHEV YLSSDGTNWGSPVASGSWFADSTTKYSNFETRPARYVRLVAVTEANGQPWTSIAE INVFQASSYTAPQPGLGRWGPTIDLPIVPAAAAIEPTSGRVLMWSSYRNDAPPGS PGGITLTSSWDPSTGIVSDRTVTVTKHDMFCPGISMDGNGQIVVTGGNDAKKTSL YDSSSDSWIPGPDMQVARGYQSSATMSDGRVFTIGGSFSGGVFEKNGEVYSPSSK TWTSLPNAKVNPMLTADKQGLYMSDNHAWLFGWKKGSVFQAGPSTAMNWYYTSGS GDVKSAGKRQSNRGVAPDAMCGNAVMYDAVKGKILTFGGSPDYTDSDATTNAHII TLGEPGTSPNTVFASNGLYFARTFHTSVVLPDGSTFITGGQRRGIPFEDSTPVFT PEIYVPEQDTFYKQNPNSIVRAYHSISLLLPDGRVFNGGGGGCGDCTTNHFDAQI FTPNYLYDSNGNLATRPKITRTSTQSVKVGGRITISTDSSITKASLIRYGTATHT VNTDQRRIPLTLTNNGGNSYSFQVPSDSGVALPGYWMLFVMNSAGVPSVASTIRV TQAAA 59 GOh1048 atgggcagcagccatcatcatcatcatcacagcagcggcctggtgccgcgcggca gccatatgggtaccgcctctgcccctatcggctcagccatcccgcgcaataactg ggccgtaacgtgcgacagcgcgcagagcggcaacgagtgcaataaagccatcgac ggcaataaagacaccttctggcacacgttttatggcgcaaatggcgacccgaagc caccgcatacctataccattgacatgaaaaccacccagaatgtgaacgggctgtc cgtgctgccgcgccaggacggcaatcagaacggatggatcggccgtcacgaggta tatttaagctccgacggcaccaactggggatccccggtcgcgtcgggcagctggt tcgccgacagcaccaccaagtattccaattttgaaacccgtcctgcacgctacgt gcgcttagtggccgtgacagaggcgaacggccagccatggacctcaatcgccgaa atcaatgtattccaagccagctcctataccgcgccgcagccaggacttgggcgtt ggggcccgaccatcgacctgcctatcgtacccgcagccgcggcgattgaaccaac gtcaggccgcgtactgatgtggagcagctaccgtaacgacgcggttccaggcagc ccgggcggcatcactctgacgtcgagttgggatccatccacgggcatcgtctccg accgcaccgtgaccgtcacgaaacacgacatgttttgcccggggatcagcatgga cggcaacggccagatcgtcgtcacgggcggcaatgacgccaagaagacgagcctc tatgacagtagcagcgacagttggatcccggggccggacatgcaggtggcacgcg ggtaccagtccagcgcgaccatgtcagacggccgtgtctttacaatcggcggctc atttagtggcggagtgtttgagaagaatggcgaagtctatagcccctcatccaaa acgtggacgtcacttccgaacgcgaaggtgaatcccatgttaaccgccgacaaac agggcctgtacatgagcgacaaccatgcgtggctgttcggctggaagaaggggag cgtctttcaggcgggcccgtcgaccgcaatgaattggtattacacgtcaggaagc ggggacgtgaaatcagccggcaagcgccagtcgaaccgcggcgtggcgccggacg caatgtgcggcaatgccgtgatgtatgacgcggtcaaaggcaagatcctgacatt tggcgggagtccggactacaccgacagtgacgcgacaaccaatgcccacattatt acccttggggagccggggacgagcccgaacacggtcttcgcgtccaatggcctct atttcgcgcgtacctttcatacgtcggtggtcctgccggacggatcaacctttat caccggcggacagcgccgtggcatccccttcgaagactcgacccccgtctttaca ccggagatttatgtgccggaacaggacacgttttataaacagaatccgaactcga ttgtacgcgcgtatcactccatcagccttcttctcccggacggacgtgtctttaa tggcggaggaggactgtgcggggactgcacgaccaatcattttgacgcgcagatc tttaccccgaattatctgtatgattcaaatgggaatctcgcgacccgtccgaaaa ttacccgtacatcaacccagtccgtcaaagtgggcggccgcattacgatcagtac cgacagcagcattaccaaagcgtcactgattcgttacggcaccgcaacccataca gtcaacacggaccagcgccgtattccgttaaccctgaccaataacggtggcaatt cgtatagcttccaggtaccgtcggactcgggcgtggcgctgccaggatactggat gctgtttgtgatgaatagcgcgggcgtcccgagcgtagcgagcacgatccgtgtg acccaggccgcagcttgataa 60 GOh1048 MGSSHHHHHHSSGLVPRGSHMGTASAPIGSAIPRNNWAVTCDSAQSGNECNKAID GNKDTFWHTFYGANGDPKPPHTYTIDMKTTQNVNGLSVLPRQDGNQNGWIGRHEV YLSSDGTNWGSPVASGSWFADSTTKYSNFETRPARYVRLVAVTEANGQPWTSIAE INVFQASSYTAPQPGLGRWGPTIDLPIVPAAAAIEPTSGRVLMWSSYRNDAVPGS PGGITLTSSWDPSTGIVSDRTVTVTKHDMFCPGISMDGNGQIVVTGGNDAKKTSL YDSSSDSWIPGPDMQVARGYQSSATMSDGRVFTIGGSFSGGVFEKNGEVYSPSSK TWTSLPNAKVNPMLTADKQGLYMSDNHAWLFGWKKGSVFQAGPSTAMNWYYTSGS GDVKSAGKRQSNRGVAPDAMCGNAVMYDAVKGKILTFGGSPDYTDSDATTNAHII TLGEPGTSPNTVFASNGLYFARTFHTSVVLPDGSTFITGGQRRGIPFEDSTPVFT PEIYVPEQDTFYKQNPNSIVRAYHSISLLLPDGRVFNGGGGLCGDCTTNHFDAQI FTPNYLYDSNGNLATRPKITRTSTQSVKVGGRITISTDSSITKASLIRYGTATHT VNTDQRRIPLTLTNNGGNSYSFQVPSDSGVALPGYWMLFVMNSAGVPSVASTIRV TQAAA 61 GOh1049 atgggcagcagccatcatcatcatcatcacagcagcggcctggtgccgcgcggca gccatatgggtaccgcctctgcccctatcggctcagccatcccgcgcaataactg ggccgtaacgtgcgacagcgcgcagagcggcaacgagtgcaataaagccatcgac ggcaataaagacaccttctggcacacgttttatggcgcaaatggcgacccgaagc caccgcatacctataccattgacatgaaaaccacccagaatgtgaacgggctgtc cgtgctgccgcgccaggacggcaatcagaacggatggatcggccgtcacgaggta tatttaagctccgacggcaccaactggggatccccggtcgcgtcgggcagctggt tcgccgacagcaccaccaagtattccaattttgaaacccgtcctgcacgctacgt gcgcttagtggccgtgacagaggcgaacggccagccatggacctcaatcgccgaa atcaatgtattccaagccagctcctataccgcgccgcagccaggacttgggcgtt ggggcccgaccatcgacctgcctatcgtacccgcagccgcggcgattgaaccaac gtcaggccgcgtactgatgtggagcagctaccgtaacgacgcggttgaaggcagc ccgggcggcatcactctgacgtcgagttgggatccatccacgggcatcgtctccg accgcaccgtgaccgtcacgaaacacgacatgttttgcccggggatcagcatgga cggcaacggccagatcgtcgtcacgggcggcaatgacgccaagaagacgagcctc tatgacagtagcagcgacagttggatcccggggccggacatgcaggtggcacgcg ggtaccagtccagcgcgaccatgtcagacggccgtgtctttacaatcggcggctc atttagtggcggagtgtttgagaagaatggcgaagtctatagcccctcatccaaa acgtggacgtcacttccgaacgcgaaggtgaatcccatgttaaccgccgacaaac agggcctgtacatgagcgacaaccatgcgtggctgttcggctggaagaaggggag cgtctttcaggcgggcccgtcgaccgcaatgaattggtattacacgtcaggaagc ggggacgtgaaatcagccggcaagcgccagtcgaaccgcggcgtggcgccggacg caatgtgcggcaatgccgtgatgtatgacgcggtcaaaggcaagatcctgacatt tggcgggagtccggactacaccgacagtgacgcgacaaccaatgcccacattatt acccttggggagccggggacgagcccgaacacggtcttcgcgtccaatggcctct atttcgcgcgtacctttcatacgtcggtggtcctgccggacggatcaacctttat caccggcggacagcgccgtggcatccccttcgaagactcgacccccgtctttaca ccggagatttatgtgccggaacaggacacgttttataaacagaatccgaactcga ttgtacgcgcgtatcactccatcagccttcttctcccggacggacgtgtctttaa tggcggaggaggagggtgcggggactgcacgaccaatcattttgacgcgcagatc tttaccccgaattatctgtatgattcaaatgggaatctcgcgacccgtccgaaaa ttacccgtacatcaacccagtccgtcaaagtgggcggccgcattacgatcagtac cgacagcagcattaccaaagcgtcactgattcgttacggcaccgcaacccataca gtcaacacggaccagcgccgtattccgttaaccctgaccaataacggtggcaatt cgtatagcttccaggtaccgtcggactcgggcgtggcgctgccaggatactggat gctgtttgtgatgaatagcgcgggcgtcccgagcgtagcgagcacgatccgtgtg acccaggccgcagcttgataa 62 GOh1049 MGSSHHHHHHSSGLVPRGSHMGTASAPIGSAIPRNNWAVTCDSAQSGNECNKAID GNKDTFWHTFYGANGDPKPPHTYTIDMKTTQNVNGLSVLPRQDGNQNGWIGRHEV YLSSDGTNWGSPVASGSWFADSTTKYSNFETRPARYVRLVAVTEANGQPWTSIAE INVFQASSYTAPQPGLGRWGPTIDLPIVPAAAAIEPTSGRVLMWSSYRNDAVEGS PGGITLTSSWDPSTGIVSDRTVTVTKHDMFCPGISMDGNGQIVVTGGNDAKKTSL YDSSSDSWIPGPDMQVARGYQSSATMSDGRVFTIGGSFSGGVFEKNGEVYSPSSK TWTSLPNAKVNPMLTADKQGLYMSDNHAWLFGWKKGSVFQAGPSTAMNWYYTSGS GDVKSAGKRQSNRGVAPDAMCGNAVMYDAVKGKILTFGGSPDYTDSDATTNAHII TLGEPGTSPNTVFASNGLYFARTFHTSVVLPDGSTFITGGQRRGIPFEDSTPVFT PEIYVPEQDTFYKQNPNSIVRAYHSISLLLPDGRVFNGGGGGCGDCTTNHFDAQI FTPNYLYDSNGNLATRPKITRTSTQSVKVGGRITISTDSSITKASLIRYGTATHT VNTDQRRIPLTLTNNGGNSYSFQVPSDSGVALPGYWMLFVMNSAGVPSVASTIRV TQAAA 63 GOh1050 atgggcagcagccatcatcatcatcatcacagcagcggcctggtgccgcgcggca gccatatgggtaccgcctctgcccctatcggctcagccatcccgcgcaataactg ggccgtaacgtgcgacagcgcgcagagcggcaacgagtgcaataaagccatcgac ggcaataaagacaccttctggcacacgttttatggcgcaaatggcgacccgaagc caccgcatacctataccattgacatgaaaaccacccagaatgtgaacgggctgtc cgtgctgccgcgccaggacggcaatcagaacggatggatcggccgtcacgaggta tatttaagctccgacggcaccaactggggatccccggtcgcgtcgggcagctggt tcgccgacagcaccaccaagtattccaattttgaaacccgtcctgcacgctacgt gcgcttagtggccgtgacagaggcgaacggccagccatggacctcaatcgccgaa atcaatgtattccaagccagctcctataccgcgccgcagccaggacttgggcgtt ggggcccgaccatcgacctgcctatcgtacccgcagccgcggcgattgaaccaac gtcaggccgcgtactgatgtggagcagctaccgtaacgacgcggttccaggcagc ccgggggcatcactctgacgtcgagttgggatccatccacgggcatcgtctccga ccgcaccgtgaccgtcacgaaacacgacatgttttgcccggggatcagcatggac ggcaacggccagatcgtcgtcacgggcggcaatgacgccaagaagacgagcctct atgacagtagcagcgacagttggatcccggggccggacatgcaggtggcacgcgg gtaccagtccagcgcgaccatgtcagacggccgtgtctttacaatcggcggctca tttagtggcggagtgtttgagaagaatggcgaagtctatagcccctcatccaaaa cgtggacgtcacttccgaacgcgaaggtgaatcccatgttaaccgccgacaaaca gggcctgtacatgagcgacaaccatgcgtggctgttcggctggaagaaggggagc gtctttcaggcgggcccgtcgaccgcaatgaattggtattacacgtcaggaagcg gggacgtgaaatcagccggcaagcgccagtcgaaccgcggcgtggcgccggacgc aatgtgcggcaatgccgtgatgtatgacgcggtcaaaggcaagatcctgacattt ggcgggagtccggactacaccgacagtgacgcgacaaccaatgcccacattatta cccttggggagccggggacgagcccgaacacggtcttcgcgtccaatggcctcta tttcgcgcgtacctttcatacgtcggtggtcctgccggacggatcaacctttatc accggcggacagcgccgtggcatccccttcgaagactcgacccccgtctttacac cggagatttatgtgccggaacaggacacgttttataaacagaatccgaactcgat tgtacgcgcgtatcactccatcagccttcttctcccggacggacgtgtctttaat ggcggaggaggagggtgcggggactgcacgaccaatcattttgacgcgcagatct ttaccccgaattatctgtatgattcaaatgggaatctcgcgacccgtccgaaaat tacccgtacatcaacccagtccgtcaaagtgggcggccgcattacgatcagtacc gacagcagcattaccaaagcgtcactgattcgttacggcaccgcaacccatacag tcaacacggaccagcgccgtattccgttaaccctgaccaataacggtggcaattc gtatagcttccaggtaccgtcggactcgggcgtggcgctgccaggatactggatg ctgtttgtgatgaatagcgcgggcgtcccgagcgtagcgagcacgatccgtgtga cccaggccgcagcttgataa 64 GOh1050 MGSSHHHHHHSSGLVPRGSHMGTASAPIGSAIPRNNWAVTCDSAQSGNECNKAID GNKDTFWHTFYGANGDPKPPHTYTIDMKTTQNVNGLSVLPRQDGNQNGWIGRHEV YLSSDGTNWGSPVASGSWFADSTTKYSNFETRPARYVRLVAVTEANGQPWTSIAE INVFQASSYTAPQPGLGRWGPTIDLPIVPAAAAIEPTSGRVLMWSSYRNDAVPGS PGGITLTSSWDPSTGIVSDRTVTVTKHDMFCPGISMDGNGQIVVTGGNDAKKTSL YDSSSDSWIPGPDMQVARGYQSSATMSDGRVFTIGGSFSGGVFEKNGEVYSPSSK TWTSLPNAKVNPMLTADKQGLYMSDNHAWLFGWKKGSVFQAGPSTAMNWYYTSGS GDVKSAGKRQSNRGVAPDAMCGNAVMYDAVKGKILTFGGSPDYTDSDATTNAHII TLGEPGTSPNTVFASNGLYFARTFHTSVVLPDGSTFITGGQRRGIPFEDSTPVFT PEIYVPEQDTFYKQNPNSIVRAYHSISLLLPDGRVFNGGGGGCGDCTTNHFDAQI FTPNYLYDSNGNLATRPKITRTSTQSVKVGGRITISTDSSITKASLIRYGTATHT VNTDQRRIPLTLTNNGGNSYSFQVPSDSGVALPGYWMLFVMNSAGVPSVASTIRV TQAAA 65 GOh1051 atgggcagcagccatcatcatcatcatcacagcagcggcctggtgccgcgcggca gccatatgggtaccgcctctgcccctatcggctcagccatcccgcgcaataactg ggccgtaacgtgcgacagcgcgcagagcggcaacgagtgcaataaagccatcgac ggcaataaagacaccttctggcacacgttttatggcgcaaatggcgacccgaagc caccgcatacctataccattgacatgaaaaccacccagaatgtgaacgggctgtc cgtgctgccgcgccaggacggcaatcagaacggatggatcggccgtcacgaggta tatttaagctccgacggcaccaactggggatccccggtcgcgtcgggcagctggt tcgccgacagcaccaccaagtattccaattttgaaacccgtcctgcacgctacgt gcgcttagtggccgtgacagaggcgaacggccagccatggacctcaatcgccgaa atcaatgtattccaagccagctcctataccgcgccgcagccaggacttgggcgtt ggggcccgaccatcgacctgcctatcgtacccgcagccgcggcgattgaaccaac gtcaggccgcgtactgatgtggagcagctaccgtaacgacgcgttcccaggcagc ccgggcggcatcactctgacgtcgagttgggatccatccacgggcatcgtctccg accgcaccgtgaccgtcacgaaacacgacatgttttgcccggggatcagcatgga cggcaacggccagatcgtcgtcacgggcggcaatgacgccaagaagacgagcctc tatgacagtagcagcgacagttggatcccggggccggacatgcaggtggcacgcg ggtaccagtccagcgcgaccatgtcagacggccgtgtctttacaatcggcggctc atttagtggcggagtgtttgagaagaatggcgaagtctatagcccctcatccaaa acgtggacgtcacttccgaacgcgaaggtgaatcccatgttaaccgccgacaaac agggcctgtacatgagcgacaaccatgcgtggctgttcggctggaagaaggggag cgtctttcaggcgggcccgtcgaccgcaatgaattggtattacacgtcaggaagc ggggacgtgaaatcagccggcaagcgccagtcgaaccgcggcgtggcgccggacg caatgtgcggcaatgccgtgatgtatgacgcggtcaaaggcaagatcctgacatt tggcgggagtccggactacaccgacagtgacgcgacaaccaatgcccacattatt acccttggggagccggggacgagcccgaacacggtcttcgcgtccaatggcctct atttcgcgcgtacctttcatacgtcggtggtcctgccggacggatcaacctttat caccggcggacagcgccgtggcatccccttcgaagactcgacccccgtctttaca ccggagatttatgtgccggaacaggacacgttttataaacagaatccgaactcga ttgtacgcgcgtatcactccatcagccttcttctcccggacggacgtgtctttaa tggcggaggaggagggtgcggggactgcacgaccaatcattttgacgcgcagatc tttaccccgaattatctgtatgattcaaatgggaatctcgcgacccgtccgaaaa ttacccgtacatcaacccagtccgtcaaagtgggcggccgcattacgatcagtac cgacagcagcattaccaaagcgtcactgattcgttacggcaccgcaacccataca gtcaacacggaccagcgccgtattccgttaaccctgaccaataacggtggcaatt cgtatagcttccaggtaccgtcggactcgggcgtggcgctgccaggatactggat gctgtttgtgatgaatagcgcgggcgtcccgagcgtagcgagcacgatccgtgtg acccaggccgcagcttgataa 66 GOh1051 MGSSHHHHHHSSGLVPRGSHMGTASAPIGSAIPRNNWAVTCDSAQSGNECNKAID GNKDTFWHTFYGANGDPKPPHTYTIDMKTTQNVNGLSVLPRQDGNQNGWIGRHEV YLSSDGTNWGSPVASGSWFADSTTKYSNFETRPARYVRLVAVTEANGQPWTSIAE INVFQASSYTAPQPGLGRWGPTIDLPIVPAAAAIEPTSGRVLMWSSYRNDAFPGS PGGITLTSSWDPSTGIVSDRTVTVTKHDMFCPGISMDGNGQIVVTGGNDAKKTSL YDSSSDSWIPGPDMQVARGYQSSATMSDGRVFTIGGSFSGGVFEKNGEVYSPSSK TWTSLPNAKVNPMLTADKQGLYMSDNHAWLFGWKKGSVFQAGPSTAMNWYYTSGS GDVKSAGKRQSNRGVAPDAMCGNAVMYDAVKGKILTFGGSPDYTDSDATTNAHII TLGEPGTSPNTVFASNGLYFARTFHTSVVLPDGSTFITGGQRRGIPFEDSTPVFT PEIYVPEQDTFYKQNPNSIVRAYHSISLLLPDGRVFNGGGGGCGDCTTNHFDAQI FTPNYLYDSNGNLATRPKITRTSTQSVKVGGRITISTDSSITKASLIRYGTATHT VNTDQRRIPLTLTNNGGNSYSFQVPSDSGVALPGYWMLFVMNSAGVPSVASTIRV TQAAA 67 GOh1052 atgggcagcagccatcatcatcatcatcacagcagcggcctggtgccgcgcggca gccatatgggtaccgcctctgcccctatcggctcagccatcccgcgcaataactg ggccgtaacgtgcgacagcgcgcagagcggcaacgagtgcaataaagccatcgac ggcaataaagacaccttctggcacacgttttatggcgcaaatggcgacccgaagc caccgcatacctataccattgacatgaaaaccacccagaatgtgaacgggctgtc cgtgctgccgcgccaggacggcaatcagaacggatggatcggccgtcacgaggta tatttaagctccgacggcaccaactggggatccccggtcgcgtcgggcagctggt tcgccgacagcaccaccaagtattccaattttgaaacccgtcctgcacgctacgt gcgcttagtggccgtgacagaggcgaacggccagccatggacctcaatcgccgaa atcaatgtattccaagccagctcctataccgcgccgcagccaggacttgggcgtt ggggcccgaccatcgacctgcctatcgtacccgcagccgcggcgattgaaccaac gtcaggccgcgtactgatgtggagcagctaccgtaacgacgcggcggaaggcagc ccgggcggcatcactctgacgtcgagttgggatccatccacgggcatcgtctccg accgcaccgtgaccgtcacgaaacacgacatgttttgcccggggatcagcatgga cggcaacggccagatcgtcgtcacgggcggctgggacgccaagaagacgagcctc tatgacagtagcagcgacagttggatcccggggccggacatgcaggtggcacgcg ggtaccagtccagcgcgaccatgtcagacggccgtgtctttacaatcggcggctc atttagtggcggagtgtttgagaagaatggcgaagtctatagcccctcatccaaa acgtggacgtcacttccgaacgcgaaggtgaatcccatgttaaccgccgacaaac agggcctgtacatgagcgacaaccatgcgtggctgttcggctggaagaaggggag cgtctttcaggcgggcccgtcgaccgcaatgaattggtattacacgtcaggaagc ggggacgtgaaatcagccggcaagcgccagtcgaaccgcggcgtggcgccggacg caatgtgcggcaatgccgtgatgtatgacgcggtcaaaggcaagatcctgacatt tgggggagtccggactacaccgacagtgacgcgacaaccaatgcccacattatta cccttggggagccggggacgagcccgaacacggtcttcgcgtccaatggcctcta tttcgcgcgtacctttcatacgtcggtggtcctgccggacggatcaacctttatc accggcggacagcgccgtggcatccccttcgaagactcgacccccgtctttacac cggagatttatgtgccggaacaggacacgttttataaacagaatccgaactcgat tgtacgcgcgtatcactccatcagccttcttctcccggacggacgtgtctttaat ggcggaggaggactgtgcggggactgcacgaccaatcattttgacgcgcagatct ttaccccgaattatctgtatgattcaaatgggaatctcgcgacccgtccgaaaat tacccgtacatcaacccagtccgtcaaagtgggcggccgcattacgatcagtacc gacagcagcattaccaaagcgtcactgattcgttacggcaccgcaacccatacag tcaacacggaccagcgccgtattccgttaaccctgaccaataacggtggcaattc gtatagcttccaggtaccgtcggactcgggcgtggcgctgccaggatactggatg ctgtttgtgatgaatagcgcgggcgtcccgagcgtagcgagcacgatccgtgtga cccaggccgcagcttgataa 68 GOh1052 MGSSHHHHHHSSGLVPRGSHMGTASAPIGSAIPRNNWAVTCDSAQSGNECNKAID GNKDTFWHTFYGANGDPKPPHTYTIDMKTTQNVNGLSVLPRQDGNQNGWIGRHEV YLSSDGTNWGSPVASGSWFADSTTKYSNFETRPARYVRLVAVTEANGQPWTSIAE INVFQASSYTAPQPGLGRWGPTIDLPIVPAAAAIEPTSGRVLMWSSYRNDAAEGS PGGITLTSSWDPSTGIVSDRTVTVTKHDMFCPGISMDGNGQIVVTGGWDAKKTSL YDSSSDSWIPGPDMQVARGYQSSATMSDGRVFTIGGSFSGGVFEKNGEVYSPSSK TWTSLPNAKVNPMLTADKQGLYMSDNHAWLFGWKKGSVFQAGPSTAMNWYYTSGS GDVKSAGKRQSNRGVAPDAMCGNAVMYDAVKGKILTFGGSPDYTDSDATTNAHII TLGEPGTSPNTVFASNGLYFARTFHTSVVLPDGSTFITGGQRRGIPFEDSTPVFT PEIYVPEQDTFYKQNPNSIVRAYHSISLLLPDGRVFNGGGGLCGDCTTNHFDAQI FTPNYLYDSNGNLATRPKITRTSTQSVKVGGRITISTDSSITKASLIRYGTATHT VNTDQRRIPLTLTNNGGNSYSFQVPSDSGVALPGYWMLFVMNSAGVPSVASTIRV TQAAA 69 GOh1053 atgggcagcagccatcatcatcatcatcacagcagcggcctggtgccgcgcggca gccatatgggtaccgcctctgcccctatcggctcagccatcccgcgcaataactg ggccgtaacgtgcgacagcgcgcagagcggcaacgagtgcaataaagccatcgac ggcaataaagacaccttctggcacacgttttatggcgcaaatggcgacccgaagc caccgcatacctataccattgacatgaaaaccacccagaatgtgaacgggctgtc cgtgctgccgcgccaggacggcaatcagaacggatggatcggccgtcacgaggta tatttaagctccgacggcaccaactggggatccccggtcgcgtcgggcagctggt tcgccgacagcaccaccaagtattccaattttgaaacccgtcctgcacgctacgt gcgcttagtggccgtgacagaggcgaacggccagccatggacctcaatcgccgaa atcaatgtattccaagccagctcctataccgcgccgcagccaggacttgggcgtt ggggcccgaccatcgacctgcctatcgtacccgcagccgcggcgattgaaccaac gtcaggccgcgtactgatgtggagcagctaccgtaacgacgcggcggaaggcagc ccgggggcatcactctgacgtcgagttgggatccatccacgggcatcgtctccga ccgcaccgtgaccgtcacgaaacacgacatgttttgcccggggatcagcatggac ggcaacggccagatcgtcgtcacgggcggctgggacgccaagaagacgagcctct atgacagtagcagcgacagttggatcccggggccggacatgcaggtggcacgcgg gtaccagtccagcgcgaccatgtcagacggccgtgtctttacaatcggcggctca tttagtggcggagtgtttgagaagaatggcgaagtctatagcccctcatccaaaa cgtggacgtcacttccgaacgcgaaggtgaatcccatgttaaccgccgacaaaca gggcctgtactttagcgacaaccatgcgtggctgttcggctggaagaaggggagc gtctttcagggggcccgtcgaccgcaatgaattggtattacacgtcaggaagcgg ggacgtgaaatcagccggcaagcgccagtcgaaccgcggcgtggcgccggacgca atgtgcggcaatgccgtgatgtatgacgcggtcaaaggcaagatcctgacatttg gcgggagtccggactacaccgacagtgacgcgacaaccaatgcccacattattac ccttggggagccggggacgagcccgaacacggtcttcgcgtccaatggcctctat ttcgcgcgtacctttcatacgtcggtggtcctgccggacggatcaacctttatca ccggcggacagcgccgtggcatccccttcgaagactcgacccccgtctttacacc ggagatttatgtgccggaacaggacacgttttataaacagaatccgaactcgatt gtacgcgcgtatcactccatcagccttcttctcccggacggacgtgtctttaatg gcggaggaggactgtgcggggactgcacgaccaatcattttgacgcgcagatctt taccccgaattatctgtatgattcaaatgggaatctcgcgacccgtccgaaaatt acccgtacatcaacccagtccgtcaaagtgggcggccgcattacgatcagtaccg acagcagcattaccaaagcgtcactgattcgttacggcaccgcaacccatacagt caacacggaccagcgccgtattccgttaaccctgaccaataacggtggcaattcg tatagcttccaggtaccgtcggactcgggcgtggcgctgccaggatactggatgc tgtttgtgatgaatagcgcgggcgtcccgagcgtagcgagcacgatccgtgtgac ccaggccgcagcttgataa 70 GOh1053 MGSSHHHHHHSSGLVPRGSHMGTASAPIGSAIPRNNWAVTCDSAQSGNECNKAID GNKDTFWHTFYGANGDPKPPHTYTIDMKTTQNVNGLSVLPRQDGNQNGWIGRHEV YLSSDGTNWGSPVASGSWFADSTTKYSNFETRPARYVRLVAVTEANGQPWTSIAE INVFQASSYTAPQPGLGRWGPTIDLPIVPAAAAIEPTSGRVLMWSSYRNDAAEGS PGGITLTSSWDPSTGIVSDRTVTVTKHDMFCPGISMDGNGQIVVTGGWDAKKTSL YDSSSDSWIPGPDMQVARGYQSSATMSDGRVFTIGGSFSGGVFEKNGEVYSPSSK TWTSLPNAKVNPMLTADKQGLYFSDNHAWLFGWKKGSVFQAGPSTAMNWYYTSGS GDVKSAGKRQSNRGVAPDAMCGNAVMYDAVKGKILTFGGSPDYTDSDATTNAHII TLGEPGTSPNTVFASNGLYFARTFHTSVVLPDGSTFITGGQRRGIPFEDSTPVFT PEIYVPEQDTFYKQNPNSIVRAYHSISLLLPDGRVFNGGGGLCGDCTTNHFDAQI FTPNYLYDSNGNLATRPKITRTSTQSVKVGGRITISTDSSITKASLIRYGTATHT VNTDQRRIPLTLTNNGGNSYSFQVPSDSGVALPGYWMLFVMNSAGVPSVASTIRV TQAAA 71 GOh1054 atgggcagcagccatcatcatcatcatcacagcagcggcctggtgccgcgcggca gccatatgggtaccgcctctgcccctatcggctcagccatcccgcgcaataactg ggccgtaacgtgcgacagcgcgcagagcggcaacgagtgcaataaagccatcgac ggcaataaagacaccttctggcacacgttttatggcgcaaatggcgacccgaagc caccgcatacctataccattgacatgaaaaccacccagaatgtgaacgggctgtc cgtgctgccgcgccaggacggcaatcagaacggatggatcggccgtcacgaggta tatttaagctccgacggcaccaactggggatccccggtcgcgtcgggcagctggt tcgccgacagcaccaccaagtattccaattttgaaacccgtcctgcacgctacgt gcgcttagtggccgtgacagaggcgaacggccagccatggacctcaatcgccgaa atcaatgtattccaagccagctcctataccgcgccgcagccaggacttgggcgtt ggggcccgaccatcgacctgcctatcgtacccgcagccgcggcgattgaaccaac gtcaggccgcgtactgatgtggagcagctaccgtaacgacgcggcggaaggcagc ccgggcggcatcactctgacgtcgagttgggatccatccacgggcatcgtctccg accgcaccgtgaccgtcacgaaacacgacatgttttgcccggggatcagcatgga cggcaacggccagatcgtcgtcacgggcggctgggacgccaagaagacgagcctc tatgacagtagcagcgacagttggatcccggggccggacatgcaggtggcacgcg ggtaccagtccagcgcgaccatgtcagacggccgtgtctttacaatcggcggctc attttgtggcggagtgtttgagaagaatggcgaagtctatagcccctcatccaaa acgtggacgtcacttccgaacgcgaaggtgaatcccatgttaaccgccgacaaac agggcctgtacatgagcgacaaccatgcgtggctgttcggctggaagaaggggag cgtctttcaggcgggcccgtcgaccgcaatgaattggtattacacgtcaggaagc ggggacgtgaaatcagccggcaagcgccagtcgaaccgcggcgtggcgccggacg caatgtgcggcaatgccgtgatgtatgacgcggtcaaaggcaagatcctgacatt tggcgggagtccggactacaccgacagtgacgcgacaaccaatgcccacattatt acccttggggagccggggacgagcccgaacacggtcttcgcgtccaatggcctct atttcgcgcgtacctttcatacgtcggtggtcctgccggacggatcaacctttat caccggcggacagcgccgtggcatccccttcgaagactcgacccccgtctttaca ccggagatttatgtgccggaacaggacacgttttataaacagaatccgaactcga ttgtacgcgcgtatcactccatcagccttcttctcccggacggacgtgtctttaa tggcggaggaggactgtgcggggactgcacgaccaatcattttgacgcgcagatc tttaccccgaattatctgtatgattcaaatgggaatctcgcgacccgtccgaaaa ttacccgtacatcaacccagtccgtcaaagtgggcggccgcattacgatcagtac cgacagcagcattaccaaagcgtcactgattcgttacggcaccgcaacccataca gtcaacacggaccagcgccgtattccgttaaccctgaccaataacggtggcaatt cgtatagcttccaggtaccgtcggactcgggcgtggcgctgccaggatactggat gctgtttgtgatgaatagcgcgggcgtcccgagcgtagcgagcacgatccgtgtg acccaggccgcagcttgataa 72 GOh1054 MGSSHHHHHHSSGLVPRGSHMGTASAPIGSAIPRNNWAVTCDSAQSGNECNKAID GNKDTFWHTFYGANGDPKPPHTYTIDMKTTQNVNGLSVLPRQDGNQNGWIGRHEV YLSSDGTNWGSPVASGSWFADSTTKYSNFETRPARYVRLVAVTEANGQPWTSIAE INVFQASSYTAPQPGLGRWGPTIDLPIVPAAAAIEPTSGRVLMWSSYRNDAAEGS PGGITLTSSWDPSTGIVSDRTVTVTKHDMFCPGISMDGNGQIVVTGGWDAKKTSL YDSSSDSWIPGPDMQVARGYQSSATMSDGRVFTIGGSFCGGVFEKNGEVYSPSSK TWTSLPNAKVNPMLTADKQGLYMSDNHAWLFGWKKGSVFQAGPSTAMNWYYTSGS GDVKSAGKRQSNRGVAPDAMCGNAVMYDAVKGKILTFGGSPDYTDSDATTNAHII TLGEPGTSPNTVFASNGLYFARTFHTSVVLPDGSTFITGGQRRGIPFEDSTPVFT PEIYVPEQDTFYKQNPNSIVRAYHSISLLLPDGRVFNGGGGLCGDCTTNHFDAQI FTPNYLYDSNGNLATRPKITRTSTQSVKVGGRITISTDSSITKASLIRYGTATHT VNTDQRRIPLTLTNNGGNSYSFQVPSDSGVALPGYWMLFVMNSAGVPSVASTIRV TQAAA 73 GOh1055 atgggcagcagccatcatcatcatcatcacagcagcggcctggtgccgcgcggca gccatatgggtaccgcctctgcccctatcggctcagccatcccgcgcaataactg ggccgtaacgtgcgacagcgcgcagagcggcaacgagtgcaataaagccatcgac ggcaataaagacaccttctggcacacgttttatggcgcaaatggcgacccgaagc caccgcatacctataccattgacatgaaaaccacccagaatgtgaacgggctgtc cgtgctgccgcgccaggacggcaatcagaacggatggatcggccgtcacgaggta tatttaagctccgacggcaccaactggggatccccggtcgcgtcgggcagctggt tcgccgacagcaccaccaagtattccaattttgaaacccgtcctgcacgctacgt gcgcttagtggccgtgacagaggcgaacggccagccatggacctcaatcgccgaa atcaatgtattccaagccagctcctataccgcgccgcagccaggacttgggcgtt ggggcccgaccatcgacctgcctatcgtacccgcagccgcggcgattgaaccaac gtcaggccgcgtactgatgtggagcagctaccgtaacgacgcgggtgaaggcagc ccgggcggcatcactctgacgtcgagttgggatccatccacgggcatcgtctccg accgcaccgtgaccgtcacgaaacacgacatgttttgcccggggatcagcatgga cggcaacggccagatcgtcgtcacgggcggctgggacgccaagaagacgagcctc tatgacagtagcagcgacagttggatcccggggccggacatgcaggtggcacgcg ggtaccagtccagcgcgaccatgtcagacggccgtgtctttacaatcggcggctc atttagtggcggagtgtttgagaagaatggcgaagtctatagcccctcatccaaa acgtggacgtcacttccgaacgcgaaggtgaatcccatgttaaccgccgacaaac agggcctgtacatgagcgacaaccatgcgtggctgttcggctggaagaaggggag cgtctttcaggcgggcccgtcgaccgcaatgaattggtattacacgtcaggaagc ggggacgtgaaatcagccggcaagcgccagtcgaaccgcggcgtggcgccggacg caatgtgcggcaatgccgtgatgtatgacgcggtcaaaggcaagatcctgacatt tggcgggagtccggactacaccgacagtgacgcgacaaccaatgcccacattatt acccttggggagccggggacgagcccgaacacggtcttcgcgtccaatggcctct atttcgcgcgtacctttcatacgtcggtggtcctgccggacggatcaacctttat caccggcggacagcgccgtggcatccccttcgaagactcgacccccgtctttaca ccggagatttatgtgccggaacaggacacgttttataaacagaatccgaactcga ttgtacgcgcgtatcactccatcagccttcttctcccggacggacgtgtctttaa tggcggaggaggactgtgcggggactgcacgaccaatcattttgacgcgcagatc tttaccccgaattatctgtatgattcaaatgggaatctcgcgacccgtccgaaaa ttacccgtacatcaacccagtccgtcaaagtgggcggccgcattacgatcagtac cgacagcagcattaccaaagcgtcactgattcgttacggcaccgcaacccataca gtcaacacggaccagcgccgtattccgttaaccctgaccaataacggtggcaatt cgtatagcttccaggtaccgtcggactcgggcgtggcgctgccaggatactggat gctgtttgtgatgaatagcgcgggcgtcccgagcgtagcgagcacgatccgtgtg acccaggccgcagcttgataa 74 GOh1055 MGSSHHHHHHSSGLVPRGSHMGTASAPIGSAIPRNNWAVTCDSAQSGNECNKAID GNKDTFWHTFYGANGDPKPPHTYTIDMKTTQNVNGLSVLPRQDGNQNGWIGRHEV YLSSDGTNWGSPVASGSWFADSTTKYSNFETRPARYVRLVAVTEANGQPWTSIAE INVFQASSYTAPQPGLGRWGPTIDLPIVPAAAAIEPTSGRVLMWSSYRNDAGEGS PGGITLTSSWDPSTGIVSDRTVTVTKHDMFCPGISMDGNGQIVVTGGWDAKKTSL YDSSSDSWIPGPDMQVARGYQSSATMSDGRVFTIGGSFSGGVFEKNGEVYSPSSK TWTSLPNAKVNPMLTADKQGLYMSDNHAWLFGWKKGSVFQAGPSTAMNWYYTSGS GDVKSAGKRQSNRGVAPDAMCGNAVMYDAVKGKILTFGGSPDYTDSDATTNAHII TLGEPGTSPNTVFASNGLYFARTFHTSVVLPDGSTFITGGQRRGIPFEDSTPVFT PEIYVPEQDTFYKQNPNSIVRAYHSISLLLPDGRVFNGGGGLCGDCTTNHFDAQI FTPNYLYDSNGNLATRPKITRTSTQSVKVGGRITISTDSSITKASLIRYGTATHT VNTDQRRIPLTLTNNGGNSYSFQVPSDSGVALPGYWMLFVMNSAGVPSVASTIRV TQAAA 75 GOh1056 atgggcagcagccatcatcatcatcatcacagcagcggcctggtgccgcgcggca gccatatgggtaccgcctctgcccctatcggctcagccatcccgcgcaataactg ggccgtaacgtgcgacagcgcgcagagcggcaacgagtgcaataaagccatcgac ggcaataaagacaccttctggcacacgttttatggcgcaaatggcgacccgaagc caccgcatacctataccattgacatgaaaaccacccagaatgtgaacgggctgtc cgtgctgccgcgccaggacggcaatcagaacggatggatcggccgtcacgaggta tatttaagctccgacggcaccaactggggatccccggtcgcgtcgggcagctggt tcgccgacagcaccaccaagtattccaattttgaaacccgtcctgcacgctacgt gcgcttagtggccgtgacagaggcgaacggccagccatggacctcaatcgccgaa atcaatgtattccaagccagctcctataccgcgccgcagccaggacttgggcgtt ggggcccgaccatcgacctgcctatcgtacccgcagccgcggcgattgaaccaac gtcaggccgcgtactgatgtggagcagctaccgtaacgacgcgggtgaaggcagc ccgggcggcatcactctgacgtcgagttgggatccatccacgggcatcgtctccg accgcaccgtgaccgtcacgaaacacgacatgttttgcccggggatcagcatgga cggcaacggccagatcgtcgtcacgggcggctgggacgccaagaagacgagcctc tatgacagtagcagcgacagttggatcccggggccggacatgcaggtggcacgcg ggtaccagtccagcgcgaccatgtcagacggccgtgtctttacaatcggcggctc atttagtggcggagtgtttgagaagaatggcgaagtctatagcccctcatccaaa acgtggacgtcacttccgaacgcgaaggtgaatcccatgttaaccgccgacaaac agggcctgtactttagcgacaaccatgcgtggctgttcggctggaagaaggggag cgtctttcaggcgggcccgtcgaccgcaatgaattggtattacacgtcaggaagc ggggacgtgaaatcagccggcaagcgccagtcgaaccgcggcgtggcgccggacg caatgtgcggcaatgccgtgatgtatgacgcggtcaaaggcaagatcctgacatt tgggggagtccggactacaccgacagtgacgcgacaaccaatgcccacattatta cccttggggagccggggacgagcccgaacacggtcttcgcgtccaatggcctcta tttcgcgcgtacctttcatacgtcggtggtcctgccggacggatcaacctttatc accggcggacagcgccgtggcatccccttcgaagactcgacccccgtctttacac cggagatttatgtgccggaacaggacacgttttataaacagaatccgaactcgat tgtacgcgcgtatcactccatcagccttcttctcccggacggacgtgtctttaat ggcggaggaggactgtgcggggactgcacgaccaatcattttgacgcgcagatct ttaccccgaattatctgtatgattcaaatgggaatctcgcgacccgtccgaaaat tacccgtacatcaacccagtccgtcaaagtgggcggccgcattacgatcagtacc gacagcagcattaccaaagcgtcactgattcgttacggcaccgcaacccatacag tcaacacggaccagcgccgtattccgttaaccctgaccaataacggtggcaattc gtatagcttccaggtaccgtcggactcgggcgtggcgctgccaggatactggatg ctgtttgtgatgaatagcgcgggcgtcccgagcgtagcgagcacgatccgtgtga cccaggccgcagcttgataa 76 GOh1056 MGSSHHHHHHSSGLVPRGSHMGTASAPIGSAIPRNNWAVTCDSAQSGNECNKAID GNKDTFWHTFYGANGDPKPPHTYTIDMKTTQNVNGLSVLPRQDGNQNGWIGRHEV YLSSDGTNWGSPVASGSWFADSTTKYSNFETRPARYVRLVAVTEANGQPWTSIAE INVFQASSYTAPQPGLGRWGPTIDLPIVPAAAAIEPTSGRVLMWSSYRNDAGEGS PGGITLTSSWDPSTGIVSDRTVTVTKHDMFCPGISMDGNGQIVVTGGWDAKKTSL YDSSSDSWIPGPDMQVARGYQSSATMSDGRVFTIGGSFSGGVFEKNGEVYSPSSK TWTSLPNAKVNPMLTADKQGLYFSDNHAWLFGWKKGSVFQAGPSTAMNWYYTSGS GDVKSAGKRQSNRGVAPDAMCGNAVMYDAVKGKILTFGGSPDYTDSDATTNAHII TLGEPGTSPNTVFASNGLYFARTFHTSVVLPDGSTFITGGQRRGIPFEDSTPVFT PEIYVPEQDTFYKQNPNSIVRAYHSISLLLPDGRVFNGGGGLCGDCTTNHFDAQI FTPNYLYDSNGNLATRPKITRTSTQSVKVGGRITISTDSSITKASLIRYGTATHT VNTDQRRIPLTLTNNGGNSYSFQVPSDSGVALPGYWMLFVMNSAGVPSVASTIRV TQAAA 77 GOh2001 atgggcagcagccatcatcatcatcatcacagcagcggcctggtgccgcgcggca gccatatgggtaccgcctctgcccctatcggctcagccatcccgcgcaataactg ggccgtaacgtgcgacagcgcgcagagcggcaacgagtgcaataaagccatcgac ggcaataaagacaccttctggcacacgttttatggcgcaaatggcgacccgaagc caccgcatacctataccattgacatgaaaaccacccagaatgtgaacgggctgtc cgtgctgccgcgccaggacggcaatcagaacggatggatcggccgtcacgaggta tatttaagctccgacggcaccaactggggatccccggtcgcgtcgggcagctggt tcgccgacagcaccaccaagtattccaattttgaaacccgtcctgcacgctacgt gcgcttagtggccgtgacagaggcgaacggccagccatggacctcaatcgccgaa atcaatgtattccaagccagctcctataccgcgccgcagccaggacttgggcgtt ggggcccgaccatcgacctgcctatcgtacccagcgccgcggcgattgaaccaac gtcaggccgcgtactgatgtggagcagctaccgtaacgacgcggcggaaggcagc ccgggcggcatcactctgacgtcgagttgggatccatccacgggcatcgtctccg accgcaccgtgaccgtcacgaaacacgacatgttttgcccggggatcagcatgga cggcaacggccagatcgtcgtcacgggcggctgggacgccaagaagacgagcctc tatgacagtagcagcgacagttggatcccggggccggacatgcaggtggcacgcg ggtaccagtccagcgcgaccatgtcagacggccgtgtctttacaatcggcggctc atttagtggcggagtgtttgagaagaatggcgaagtctatagcccctcatccaaa acgtggacgtcacttccgaacgcgaaggtgaatcccatgttaaccgccgacaaac agggcctgtacatgagcgacaaccatgcgtggctgttcggctggaagaaggggag cgtctttcaggcgggcccgtcgaccgcaatgaattggtattacacgtcaggaagc ggggacgtgaaatcagccggcaagcgccagtcgaaccgcggcgtggcgccggacg caatgtgcggcaatgccgtgatgtatgacgcggtcaaaggcaagatcctgacatt tggcgggagtccggactacaccgacagtgacgcgacaaccaatgcccacattatt acccttggggagccggggacgagcccgaacacggtcttcgcgtccaatggcctct atttcgcgcgtacctttcatacgtcggtggtcctgccggacggatcaacctttat caccggcggacagcgccgtggcatccccttcgaagactcgacccccgtctttaca ccggagatttatgtgccggaacaggacacgttttataaacagaatccgaactcga ttgtacgcgcgtatcactccatcagccttcttctcccggacggacgtgtctttaa tggcggaggaggactgtgcggggactgcacgaccaatcattttgacgcgcagatc tttaccccgaattatctgtatgattcaaatgggaatctcgcgacccgtccgaaaa ttacccgtacatcaacccagtccgtcaaagtgggggccgcattacgatcagtacc gacagcagcattaccaaagcgtcactgattcgttacggcaccgcaacccatacag tcaacacggaccagcgccgtattccgttaaccctgaccaataacggtggcaattc gtatagcttccaggtaccgtcggactcgggcgtggcgctgccaggatactggatg ctgtttgtgatgaatagcgcgggcgtcccgagcgtagcgagcacgatccgtgtga cccaggccgcagcttgataa 78 GOh2001 MGSSHHHHHHSSGLVPRGSHMGTASAPIGSAIPRNNWAVTCDSAQSGNECNKAID GNKDTFWHTFYGANGDPKPPHTYTIDMKTTQNVNGLSVLPRQDGNQNGWIGRHEV YLSSDGTNWGSPVASGSWFADSTTKYSNFETRPARYVRLVAVTEANGQPWTSIAE INVFQASSYTAPQPGLGRWGPTIDLPIVPSAAAIEPTSGRVLMWSSYRNDAAEGS PGGITLTSSWDPSTGIVSDRTVTVTKHDMFCPGISMDGNGQIVVTGGWDAKKTSL YDSSSDSWIPGPDMQVARGYQSSATMSDGRVFTIGGSFSGGVFEKNGEVYSPSSK TWTSLPNAKVNPMLTADKQGLYMSDNHAWLFGWKKGSVFQAGPSTAMNWYYTSGS GDVKSAGKRQSNRGVAPDAMCGNAVMYDAVKGKILTFGGSPDYTDSDATTNAHII TLGEPGTSPNTVFASNGLYFARTFHTSVVLPDGSTFITGGQRRGIPFEDSTPVFT PEIYVPEQDTFYKQNPNSIVRAYHSISLLLPDGRVFNGGGGLCGDCTTNHFDAQI FTPNYLYDSNGNLATRPKITRTSTQSVKVGGRITISTDSSITKASLIRYGTATHT VNTDQRRIPLTLTNNGGNSYSFQVPSDSGVALPGYWMLFVMNSAGVPSVASTIRV TQAAA 79 GOh2002 atgggcagcagccatcatcatcatcatcacagcagcggcctggtgccgcgcggca gccatatgggtaccgcctctgcccctatcggctcagccatcccgcgcaataactg ggccgtaacgtgcgacagcgcgcagagcggcaacgagtgcaataaagccatcgac ggcaataaagacaccttctggcacacgttttatggcgcaaatggcgacccgaagc caccgcatacctataccattgacatgaaaaccacccagaatgtgaacgggctgtc cgtgctgccgcgccaggacggcaatcagaacggatggatcggccgtcacgaggta tatttaagctccgacggcaccaactggggatccccggtcgcgtcgggcagctggt tcgccgacagcaccaccaagtattccaattttgaaacccgtcctgcacgctacgt gcgcttagtggccgtgacagaggcgaacggccagccatggacctcaatcgccgaa atcaatgtattccaagccagctcctataccgcgccgcagccaggacttgggcgtt ggggcccgaccatcgacctgcctatcacccccgcagccgcggcgattgaaccaac gtcaggccgcgtactgatgtggagcagctaccgtaacgacgcggcggaaggcagc ccgggcggcatcactctgacgtcgagttgggatccatccacgggcatcgtctccg accgcaccgtgaccgtcacgaaacacgacatgttttgcccggggatcagcatgga cggcaacggccagatcgtcgtcacgggcggctgggacgccaagaagacgagcctc tatgacagtagcagcgacagttggatcccggggccggacatgcaggtggcacgcg ggtaccagtccagcgcgaccatgtcagacggccgtgtctttacaatcggcggctc atttagtggcggagtgtttgagaagaatggcgaagtctatagcccctcatccaaa acgtggacgtcacttccgaacgcgaaggtgaatcccatgttaaccgccgacaaac agggcctgtacatgagcgacaaccatgcgtggctgttcggctggaagaaggggag cgtctttcaggcgggcccgtcgaccgcaatgaattggtattacacgtcaggaagc ggggacgtgaaatcagccggcaagcgccagtcgaaccgcggcgtggcgccggacg caatgtgcggcaatgccgtgatgtatgacgcggtcaaaggcaagatcctgacatt tggcgggagtccggactacaccgacagtgacgcgacaaccaatgcccacattatt acccttggggagccggggacgagcccgaacacggtcttcgcgtccaatggcctct atttcgcgcgtacctttcatacgtcggtggtcctgccggacggatcaacctttat caccggggacagcgccgtggcatccccttcgaagactcgacccccgtctttacac cggagatttatgtgccggaacaggacacgttttataaacagaatccgaactcgat tgtacgcgcgtatcactccatcagccttcttctcccggacggacgtgtctttaat ggcggaggaggactgtgcggggactgcacgaccaatcattttgacgcgcagatct ttaccccgaattatctgtatgattcaaatgggaatctcgcgacccgtccgaaaat tacccgtacatcaacccagtccgtcaaagtgggcggccgcattacgatcagtacc gacagcagcattaccaaagcgtcactgattcgttacggcaccgcaacccatacag tcaacacggaccagcgccgtattccgttaaccctgaccaataacggtggcaattc gtatagcttccaggtaccgtcggactcgggcgtggcgctgccaggatactggatg ctgtttgtgatgaatagcgcgggcgtcccgagcgtagcgagcacgatccgtgtga cccaggccgcagcttgataa 80 GOh2002 MGSSHHHHHHSSGLVPRGSHMGTASAPIGSAIPRNNWAVTCDSAQSGNECNKAID GNKDTFWHTFYGANGDPKPPHTYTIDMKTTQNVNGLSVLPRQDGNQNGWIGRHEV YLSSDGTNWGSPVASGSWFADSTTKYSNFETRPARYVRLVAVTEANGQPWTSIAE INVFQASSYTAPQPGLGRWGPTIDLPITPAAAAIEPTSGRVLMWSSYRNDAAEGS PGGITLTSSWDPSTGIVSDRTVTVTKHDMFCPGISMDGNGQIVVTGGWDAKKTSL YDSSSDSWIPGPDMQVARGYQSSATMSDGRVFTIGGSFSGGVFEKNGEVYSPSSK TWTSLPNAKVNPMLTADKQGLYMSDNHAWLFGWKKGSVFQAGPSTAMNWYYTSGS GDVKSAGKRQSNRGVAPDAMCGNAVMYDAVKGKILTFGGSPDYTDSDATTNAHII TLGEPGTSPNTVFASNGLYFARTFHTSVVLPDGSTFITGGQRRGIPFEDSTPVFT PEIYVPEQDTFYKQNPNSIVRAYHSISLLLPDGRVFNGGGGLCGDCTTNHFDAQI FTPNYLYDSNGNLATRPKITRTSTQSVKVGGRITISTDSSITKASLIRYGTATHT VNTDQRRIPLTLTNNGGNSYSFQVPSDSGVALPGYWMLFVMNSAGVPSVASTIRV TQAAA 81 GOh2008 atgggcagcagccatcatcatcatcatcacagcagcggcctggtgccgcgcggca gccatatgggtaccgcctctgcccctatcggctcagccatcccgcgcaataactg ggccgtaacgtgcgacagcgcgcagagcggcaacgagtgcaataaagccatcgac ggcaataaagacaccttctggcacacgttttatggcgcaaatggcgacccgaagc caccgcatacctataccattgacatgaaaaccacccagaatgtgaacgggctgtc cgtgctgccgcgccaggacggcaatcagaacggatggatcggccgtcacgaggta tatttaagctccgacggcaccaactggggatccccggtcgcgtcgggcagctggt tcgccgacagcaccaccaagtattccaattttgaaacccgtcctgcacgctacgt gcgcttagtggccgtgacagaggcgaacggccagccatggacctcaatcgccgaa atcaatgtattccaagccagctcctataccgcgccgcagccaggacttgggcgtt ggggcccgaccatcgacctgcctatcgtacccgcagccgcggcgattgaaccaac gtcaggccgcgtactgatgtggagcagctaccgtaacgacgcggcggaaggcagc ccgggcggcatcactctgacgtcgagttgggatccatccacgggcatcgtctccg accgcaccgtgaccgtcacgaaacacgacatgttttgcccggggatcagcatgga cggcaccggccagatcgtcgtcacgggcggctgggacgccaagaagacgagcctc tatgacagtagcagcgacagttggatcccggggccggacatgcaggtggcacgcg ggtaccagtccagcgcgaccatgtcagacggccgtgtctttacaatcggcggctc atttagtggcggagtgtttgagaagaatggcgaagtctatagcccctcatccaaa acgtggacgtcacttccgaacgcgaaggtgaatcccatgttaaccgccgacaaac agggcctgtacatgagcgacaaccatgcgtggctgttcggctggaagaaggggag cgtctttcaggcgggcccgtcgaccgcaatgaattggtattacacgtcaggaagc ggggacgtgaaatcagccggcaagcgccagtcgaaccgcggcgtggcgccggacg caatgtgcggcaatgccgtgatgtatgacgcggtcaaaggcaagatcctgacatt tggcgggagtccggactacaccgacagtgacgcgacaaccaatgcccacattatt acccttggggagccggggacgagcccgaacacggtcttcgcgtccaatggcctct atttcgcgcgtacctttcatacgtcggtggtcctgccggacggatcaacctttat caccggcggacagcgccgtggcatccccttcgaagactcgacccccgtctttaca ccggagatttatgtgccggaacaggacacgttttataaacagaatccgaactcga ttgtacgcgcgtatcactccatcagccttcttctcccggacggacgtgtctttaa tggcggaggaggactgtgcggggactgcacgaccaatcattttgacgcgcagatc tttaccccgaattatctgtatgattcaaatgggaatctcgcgacccgtccgaaaa ttacccgtacatcaacccagtccgtcaaagtgggcggccgcattacgatcagtac cgacagcagcattaccaaagcgtcactgattcgttacggcaccgcaacccataca gtcaacacggaccagcgccgtattccgttaaccctgaccaataacggtggcaatt cgtatagcttccaggtaccgtcggactcgggcgtggcgctgccaggatactggat gctgtttgtgatgaatagcgcgggcgtcccgagcgtagcgagcacgatccgtgtg acccaggccgcagcttgataa 82 GOh2008 MGSSHHHHHHSSGLVPRGSHMGTASAPIGSAIPRNNWAVTCDSAQSGNECNKAID GNKDTFWHTFYGANGDPKPPHTYTIDMKTTQNVNGLSVLPRQDGNQNGWIGRHEV YLSSDGTNWGSPVASGSWFADSTTKYSNFETRPARYVRLVAVTEANGQPWTSIAE INVFQASSYTAPQPGLGRWGPTIDLPIVPAAAAIEPTSGRVLMWSSYRNDAAEGS PGGITLTSSWDPSTGIVSDRTVTVTKHDMFCPGISMDGTGQIVVTGGWDAKKTSL YDSSSDSWIPGPDMQVARGYQSSATMSDGRVFTIGGSFSGGVFEKNGEVYSPSSK TWTSLPNAKVNPMLTADKQGLYMSDNHAWLFGWKKGSVFQAGPSTAMNWYYTSGS GDVKSAGKRQSNRGVAPDAMCGNAVMYDAVKGKILTFGGSPDYTDSDATTNAHII TLGEPGTSPNTVFASNGLYFARTFHTSVVLPDGSTFITGGQRRGIPFEDSTPVFT PEIYVPEQDTFYKQNPNSIVRAYHSISLLLPDGRVFNGGGGLCGDCTTNHFDAQI FTPNYLYDSNGNLATRPKITRTSTQSVKVGGRITISTDSSITKASLIRYGTATHT VNTDQRRIPLTLTNNGGNSYSFQVPSDSGVALPGYWMLFVMNSAGVPSVASTIRV TQAAA 83 GOh2010 atgggcagcagccatcatcatcatcatcacagcagcggcctggtgccgcgcggca gccatatgggtaccgcctctgcccctatcggctcagccatcccgcgcaataactg ggccgtaacgtgcgacagcgcgcagagcggcaacgagtgcaataaagccatcgac ggcaataaagacaccttctggcacacgttttatggcgcaaatggcgacccgaagc caccgcatacctataccattgacatgaaaaccacccagaatgtgaacgggctgtc cgtgctgccgcgccaggacggcaatcagaacggatggatcggccgtcacgaggta tatttaagctccgacggcaccaactggggatccccggtcgcgtcgggcagctggt tcgccgacagcaccaccaagtattccaattttgaaacccgtcctgcacgctacgt gcgcttagtggccgtgacagaggcgaacggccagccatggacctcaatcgccgaa atcaatgtattccaagccagctcctataccgcgccgcagccaggacttgggcgtt ggggcccgaccatcgacctgcctatcgtacccgcagccgcggcgattgaaccaac gtcaggccgcgtactgatgtggagcagctaccgtaacgacgcggcggaaggcagc ccgggcggcatcactctgacgtcgagttgggatccatccacgggcatcgtctccg accgcaccgtgaccgtcacgaaacacgacatgttttgcccggggatcagcatgga cggcaacggccagatcgtcgtcacgggcggctgggacgccaagaagacgagcctc tatgacagtagcagcgacagttggatcccggggccggacatgcaggtggcacgcg ggtaccagtccagcgcgaccatgtcagacggccgtgtctttacaatcggcggctc atttagtggcggagtgtttgagaagaatggcgaagtcttcagcccctcatccaaa acgtggacgtcacttccgaacgcgaaggtgaatcccatgttaaccgccgacaaac agggcctgtacatgagcgacaaccatgcgtggctgttcggctggaagaaggggag cgtctttcaggcgggcccgtcgaccgcaatgaattggtattacacgtcaggaagc ggggacgtgaaatcagccggcaagcgccagtcgaaccgcggcgtggcgccggacg caatgtgcggcaatgccgtgatgtatgacgcggtcaaaggcaagatcctgacatt tggcgggagtccggactacaccgacagtgacgcgacaaccaatgcccacattatt acccttggggagccggggacgagcccgaacacggtcttcgcgtccaatggcctct atttcgcgcgtacctttcatacgtcggtggtcctgccggacggatcaacctttat caccggcggacagcgccgtggcatccccttcgaagactcgacccccgtctttaca ccggagatttatgtgccggaacaggacacgttttataaacagaatccgaactcga ttgtacgcgcgtatcactccatcagccttcttctcccggacggacgtgtctttaa tggcggaggaggactgtgcggggactgcacgaccaatcattttgacgcgcagatc tttaccccgaattatctgtatgattcaaatgggaatctcgcgacccgtccgaaaa ttacccgtacatcaacccagtccgtcaaagtgggcggccgcattacgatcagtac cgacagcagcattaccaaagcgtcactgattcgttacggcaccgcaacccataca gtcaacacggaccagcgccgtattccgttaaccctgaccaataacggtggcaatt cgtatagcttccaggtaccgtcggactcgggcgtggcgctgccaggatactggat gctgtttgtgatgaatagcgcgggcgtcccgagcgtagcgagcacgatccgtgtg acccaggccgcagcttgataa 84 GOh2010 MGSSHHHHHHSSGLVPRGSHMGTASAPIGSAIPRNNWAVTCDSAQSGNECNKAID GNKDTFWHTFYGANGDPKPPHTYTIDMKTTQNVNGLSVLPRQDGNQNGWIGRHEV YLSSDGTNWGSPVASGSWFADSTTKYSNFETRPARYVRLVAVTEANGQPWTSIAE INVFQASSYTAPQPGLGRWGPTIDLPIVPAAAAIEPTSGRVLMWSSYRNDAAEGS PGGITLTSSWDPSTGIVSDRTVTVTKHDMFCPGISMDGNGQIVVTGGWDAKKTSL YDSSSDSWIPGPDMQVARGYQSSATMSDGRVFTIGGSFSGGVFEKNGEVFSPSSK TWTSLPNAKVNPMLTADKQGLYMSDNHAWLFGWKKGSVFQAGPSTAMNWYYTSGS GDVKSAGKRQSNRGVAPDAMCGNAVMYDAVKGKILTFGGSPDYTDSDATTNAHII TLGEPGTSPNTVFASNGLYFARTFHTSVVLPDGSTFITGGQRRGIPFEDSTPVFT PEIYVPEQDTFYKQNPNSIVRAYHSISLLLPDGRVFNGGGGLCGDCTTNHFDAQI FTPNYLYDSNGNLATRPKITRTSTQSVKVGGRITISTDSSITKASLIRYGTATHT VNTDQRRIPLTLTNNGGNSYSFQVPSDSGVALPGYWMLFVMNSAGVPSVASTIRV TQAAA 85 GOh2011 atgggcagcagccatcatcatcatcatcacagcagcggcctggtgccgcgcggca gccatatgggtaccgcctctgcccctatcggctcagccatcccgcgcaataactg ggccgtaacgtgcgacagcgcgcagagcggcaacgagtgcaataaagccatcgac ggcaataaagacaccttctggcacacgttttatggcgcaaatggcgacccgaagc caccgcatacctataccattgacatgaaaaccacccagaatgtgaacgggctgtc cgtgctgccgcgccaggacggcaatcagaacggatggatcggccgtcacgaggta tatttaagctccgacggcaccaactggggatccccggtcgcgtcgggcagctggt tcgccgacagcaccaccaagtattccaattttgaaacccgtcctgcacgctacgt gcgcttagtggccgtgacagaggcgaacggccagccatggacctcaatcgccgaa atcaatgtattccaagccagctcctataccgcgccgcagccaggacttgggcgtt ggggcccgaccatcgacctgcctatcgtacccgcagccgcggcgattgaaccaac gtcaggccgcgtactgatgtggagcagctaccgtaacgacgcggcggaaggcagc ccgggcggcatcactctgacgtcgagttgggatccatccacgggcatcgtctccg accgcaccgtgaccgtcacgaaacacgacatgttttgcccggggatcagcatgga cggcaacggccagatcgtcgtcacgggcggctgggacgccaagaagacgagcctc tatgacagtagcagcgacagttggatcccggggccggacatgcaggtggcacgcg cgtaccagtccagcgcgaccatgtcagacggccgtgtctttacaatcggcggctc atttagtggcggagtgtttgagaagaatggcgaagtctatagcccctcatccaaa acgtggacgtcacttccgaacgcgaaggtgaatcccatgttaaccgccgacaaac agggcctgtacatgagcgacaaccatgcgtggctgttcggctggaagaaggggag cgtctttcaggcgggcccgtcgaccgcaatgaattggtattacacgtcaggaagc ggggacgtgaaatcagccggcaagcgccagtcgaaccgcggcgtggcgccggacg caatgtgcggcaatgccgtgatgtatgacgcggtcaaaggcaagatcctgacatt tggcgggagtccggactacaccgacagtgacgcgacaaccaatgcccacattatt acccttggggagccggggacgagcccgaacacggtcttcgcgtccaatggcctct atttcgcgcgtacctttcatacgtcggtggtcctgccggacggatcaacctttat caccggcggacagcgccgtggcatccccttcgaagactcgacccccgtctttaca ccggagatttatgtgccggaacaggacacgttttataaacagaatccgaactcga ttgtacgcgcgtatcactccatcagccttcttctcccggacggacgtgtctttaa tggcggaggaggactgtgcggggactgcacgaccaatcattttgacgcgcagatc tttaccccgaattatctgtatgattcaaatgggaatctcgcgacccgtccgaaaa ttacccgtacatcaacccagtccgtcaaagtgggcggccgcattacgatcagtac cgacagcagcattaccaaagcgtcactgattcgttacggcaccgcaacccataca gtcaacacggaccagcgccgtattccgttaaccctgaccaataacggtggcaatt cgtatagcttccaggtaccgtcggactcgggcgtggcgctgccaggatactggat gctgtttgtgatgaatagcgcgggcgtcccgagcgtagcgagcacgatccgtgtg acccaggccgcagcttgataa 86 GOh2011 MGSSHHHHHHSSGLVPRGSHMGTASAPIGSAIPRNNWAVTCDSAQSGNECNKAID GNKDTFWHTFYGANGDPKPPHTYTIDMKTTQNVNGLSVLPRQDGNQNGWIGRHEV YLSSDGTNWGSPVASGSWFADSTTKYSNFETRPARYVRLVAVTEANGQPWTSIAE INVFQASSYTAPQPGLGRWGPTIDLPIVPAAAAIEPTSGRVLMWSSYRNDAAEGS PGGITLTSSWDPSTGIVSDRTVTVTKHDMFCPGISMDGNGQIVVTGGWDAKKTSL YDSSSDSWIPGPDMQVARAYQSSATMSDGRVFTIGGSFSGGVFEKNGEVYSPSSK TWTSLPNAKVNPMLTADKQGLYMSDNHAWLFGWKKGSVFQAGPSTAMNWYYTSGS GDVKSAGKRQSNRGVAPDAMCGNAVMYDAVKGKILTFGGSPDYTDSDATTNAHII TLGEPGTSPNTVFASNGLYFARTFHTSVVLPDGSTFITGGQRRGIPFEDSTPVFT PEIYVPEQDTFYKQNPNSIVRAYHSISLLLPDGRVFNGGGGLCGDCTTNHFDAQI FTPNYLYDSNGNLATRPKITRTSTQSVKVGGRITISTDSSITKASLIRYGTATHT VNTDQRRIPLTLTNNGGNSYSFQVPSDSGVALPGYWMLFVMNSAGVPSVASTIRV TQAAA 87 GOh2012 atgggcagcagccatcatcatcatcatcacagcagcggcctggtgccgcgcggca gccatatgggtaccgcctctgcccctatcggctcagccatcccgcgcaataactg ggccgtaacgtgcgacagcgcgcagagcggcaacgagtgcaataaagccatcgac ggcaataaagacaccttctggcacacgttttatggcgcaaatggcgacccgaagc caccgcatacctataccattgacatgaaaaccacccagaatgtgaacgggctgtc cgtgctgccgcgccaggacggcaatcagaacggatggatcggccgtcacgaggta tatttaagctccgacggcaccaactggggatccccggtcgcgtcgggcagctggt tcgccgacagcaccaccaagtattccaattttgaaacccgtcctgcacgctacgt gcgcttagtggccgtgacagaggcgaacggccagccatggacctcaatcgccgaa atcaatgtattccaagccagctcctataccgcgccgcagccaggacttgggcgtt ggggcccgaccatcgacctgcctatcgtacccaccgccgcggcgattgaaccaac gtcaggccgcgtactgatgtggagcagctaccgtaacgacgcggcggaaggcagc ccgggggcatcactctgacgtcgagttgggatccatccacgggcatcgtctccga ccgcaccgtgaccgtcacgaaacacgacatgttttgcccggggatcagcatggac ggcaacggccagatcgtcgtcacgggcggctgggacgccaagaagacgagcctct atgacagtagcagcgacagttggatcccggggccggacatgcaggtggcacgcgg gtaccagtccagcgcgaccatgtcagacggccgtgtctttacaatcggcggctca tttagtggcggagtgtttgagaagaatggcgaagtctatagcccctcatccaaaa cgtggacgtcacttccgaacgcgaaggtgaatcccatgttaaccgccgacaaaca gggcctgtacatgagcgacaaccatgcgtggctgttcggctggaagaaggggagc gtctttcaggcgggcccgtcgaccgcaatgaattggtattacacgtcaggaagcg gggacgtgaaatcagccggcaagcgccagtcgaaccgcggcgtggcgccggacgc aatgtgcggcaatgccgtgatgtatgacgcggtcaaaggcaagatcctgacattt ggcgggagtccggactacaccgacagtgacgcgacaaccaatgcccacattatta cccttggggagccggggacgagcccgaacacggtcttcgcgtccaatggcctcta tttcgcgcgtacctttcatacgtcggtggtcctgccggacggatcaacctttatc accggcggacagcgccgtggcatccccttcgaagactcgacccccgtctttacac cggagatttatgtgccggaacaggacacgttttataaacagaatccgaactcgat tgtacgcgcgtatcactccatcagccttcttctcccggacggacgtgtctttaat ggcggaggaggactgtgcggggactgcacgaccaatcattttgacgcgcagatct ttaccccgaattatctgtatgattcaaatgggaatctcgcgacccgtccgaaaat tacccgtacatcaacccagtccgtcaaagtgggcggccgcattacgatcagtacc gacagcagcattaccaaagcgtcactgattcgttacggcaccgcaacccatacag tcaacacggaccagcgccgtattccgttaaccctgaccaataacggtggcaattc gtatagcttccaggtaccgtcggactcgggcgtggcgctgccaggatactggatg ctgtttgtgatgaatagcgcgggcgtcccgagcgtagcgagcacgatccgtgtga cccaggccgcagcttgataa 88 GOh2012 MGSSHHHHHHSSGLVPRGSHMGTASAPIGSAIPRNNWAVTCDSAQSGNECNKAID GNKDTFWHTFYGANGDPKPPHTYTIDMKTTQNVNGLSVLPRQDGNQNGWIGRHEV YLSSDGTNWGSPVASGSWFADSTTKYSNFETRPARYVRLVAVTEANGQPWTSIAE INVFQASSYTAPQPGLGRWGPTIDLPIVPTAAAIEPTSGRVLMWSSYRNDAAEGS PGGITLTSSWDPSTGIVSDRTVTVTKHDMFCPGISMDGNGQIVVTGGWDAKKTSL YDSSSDSWIPGPDMQVARGYQSSATMSDGRVFTIGGSFSGGVFEKNGEVYSPSSK TWTSLPNAKVNPMLTADKQGLYMSDNHAWLFGWKKGSVFQAGPSTAMNWYYTSGS GDVKSAGKRQSNRGVAPDAMCGNAVMYDAVKGKILTFGGSPDYTDSDATTNAHII TLGEPGTSPNTVFASNGLYFARTFHTSVVLPDGSTFITGGQRRGIPFEDSTPVFT PEIYVPEQDTFYKQNPNSIVRAYHSISLLLPDGRVFNGGGGLCGDCTTNHFDAQI FTPNYLYDSNGNLATRPKITRTSTQSVKVGGRITISTDSSITKASLIRYGTATHT VNTDQRRIPLTLTNNGGNSYSFQVPSDSGVALPGYWMLFVMNSAGVPSVASTIRV TQAAA 89 GOh2013 atgggcagcagccatcatcatcatcatcacagcagcggcctggtgccgcgcggca gccatatgggtaccgcctctgcccctatcggctcagccatcccgcgcaataactg ggccgtaacgtgcgacagcgcgcagagcggcaacgagtgcaataaagccatcgac ggcaataaagacaccttctggcacacgttttatggcgcaaatggcgacccgaagc caccgcatacctataccattgacatgaaaaccacccagaatgtgaacgggctgtc cgtgctgccgcgccaggacggcaatcagaacggatggatcggccgtcacgaggta tatttaagctccgacggcaccaactggggatccccggtcgcgtcgggcagctggt tcgccgacagcaccaccaagtattccaattttgaaacccgtcctgcacgctacgt gcgcttagtggccgtgacagaggcgaacggccagccatggacctcaatcgccgaa atcaatgtattccaagccagctcctataccgcgccgcagccaggacttgggcgtt ggggcccgaccatcgacctgcctatcgtacccgcagccgcggcgattgaaccaac gtcaggccgcgtactgatgtggagcagctaccgtaacgacgcggcggaaggcagc ccgggcggcatcactctgacgtcgagttgggatccatccacgggcatcgtctccg accgcaccgtgaccgtcacgaaacacgacatgttttgcccggggatcagcatgga cggcaacggccagatcgtcgtcacgggcggctgggacgccaagaagacgagcctc tatgacagtagcagcgacagttggatcccggggccggacatgcaggtggcacgcg ggtaccagtccagcgcgaccatgtcagacggccgtgtctttacaatcggcggctc atttagtggcggagtgtttgagaagaatggcgaagtctatagcccctcatccaaa acgtggacgtcacttccgaacgcgaaggtgaatcccatgttaaccgccgacaaac agggcctgaccatgagcgacaaccatgcgtggctgttcggctggaagaaggggag cgtctttcaggcgggcccgtcgaccgcaatgaattggtattacacgtcaggaagc ggggacgtgaaatcagccggcaagcgccagtcgaaccgcggcgtggcgccggacg caatgtgcggcaatgccgtgatgtatgacgcggtcaaaggcaagatcctgacatt tggcgggagtccggactacaccgacagtgacgcgacaaccaatgcccacattatt acccttggggagccggggacgagcccgaacacggtcttcgcgtccaatggcctct atttcgcgcgtacctttcatacgtcggtggtcctgccggacggatcaacctttat caccggcggacagcgccgtggcatccccttcgaagactcgacccccgtctttaca ccggagatttatgtgccggaacaggacacgttttataaacagaatccgaactcga ttgtacgcgcgtatcactccatcagccttcttctcccggacggacgtgtctttaa tggcggaggaggactgtgcggggactgcacgaccaatcattttgacgcgcagatc tttaccccgaattatctgtatgattcaaatgggaatctcgcgacccgtccgaaaa ttacccgtacatcaacccagtccgtcaaagtgggcggccgcattacgatcagtac cgacagcagcattaccaaagcgtcactgattcgttacggcaccgcaacccataca gtcaacacggaccagcgccgtattccgttaaccctgaccaataacggtggcaatt cgtatagcttccaggtaccgtcggactcgggcgtggcgctgccaggatactggat gctgtttgtgatgaatagcgcgggcgtcccgagcgtagcgagcacgatccgtgtg acccaggccgcagcttgataa 90 GOh2013 MGSSHHHHHHSSGLVPRGSHMGTASAPIGSAIPRNNWAVTCDSAQSGNECNKAID GNKDTFWHTFYGANGDPKPPHTYTIDMKTTQNVNGLSVLPRQDGNQNGWIGRHEV YLSSDGTNWGSPVASGSWFADSTTKYSNFETRPARYVRLVAVTEANGQPWTSIAE INVFQASSYTAPQPGLGRWGPTIDLPIVPAAAAIEPTSGRVLMWSSYRNDAAEGS PGGITLTSSWDPSTGIVSDRTVTVTKHDMFCPGISMDGNGQIVVTGGWDAKKTSL YDSSSDSWIPGPDMQVARGYQSSATMSDGRVFTIGGSFSGGVFEKNGEVYSPSSK TWTSLPNAKVNPMLTADKQGLTMSDNHAWLFGWKKGSVFQAGPSTAMNWYYTSGS GDVKSAGKRQSNRGVAPDAMCGNAVMYDAVKGKILTFGGSPDYTDSDATTNAHII TLGEPGTSPNTVFASNGLYFARTFHTSVVLPDGSTFITGGQRRGIPFEDSTPVFT PEIYVPEQDTFYKQNPNSIVRAYHSISLLLPDGRVFNGGGGLCGDCTTNHFDAQI FTPNYLYDSNGNLATRPKITRTSTQSVKVGGRITISTDSSITKASLIRYGTATHT VNTDQRRIPLTLTNNGGNSYSFQVPSDSGVALPGYWMLFVMNSAGVPSVASTIRV TQAAA 91 GOh2014 atgggcagcagccatcatcatcatcatcacagcagcggcctggtgccgcgcggca gccatatgggtaccgcctctgcccctatcggctcagccatcccgcgcaataactg ggccgtaacgtgcgacagcgcgcagagcggcaacgagtgcaataaagccatcgac ggcaataaagacaccttctggcacacgttttatggcgcaaatggcgacccgaagc caccgcatacctataccattgacatgaaaaccacccagaatgtgaacgggctgtc cgtgctgccgcgccaggacggcaatcagaacggatggatcggccgtcacgaggta tatttaagctccgacggcaccaactggggatccccggtcgcgtcgggcagctggt tcgccgacagcaccaccaagtattccaattttgaaacccgtcctgcacgctacgt gcgcttagtggccgtgacagaggcgaacggccagccatggacctcaatcgccgaa atcaatgtattccaagccagctcctataccgcgccgcagccaggacttgggcgtt ggggcccgaccatcgacctgcctatcgtacccgcagccgcggcgattgaaccaac gtcaggccgcgtactgatgtggagcagctaccgtaacgacgcggcggaaggcagc ccgggcggcatcactctgacgtcgagttgggatccatccacgggcatcgtctccg accgcaccgtgaccgtcacgaaacacgacatgttttgcccggggatcagcatgga cggcaacggccagatcgtcgtcacgggcggctgggacgccaagaagacgagcctc tatgacagtagcagcgacagttggatcccggggccggacatgcaggtggcacgcg ggtaccagtccagcgcgaccatgtcagacggccgtgtctttacaatcggcggctc atttagtggcggagtgtttgagaagaatggcgaagtctatagcccctcatccaaa acgtggacgtcacttccgaacgcgaaggtgtggcccatgttaaccgccgacaaac agggcctgtacatgagcgacaaccatgcgtggctgttcggctggaagaaggggag cgtctttcaggcgggcccgtcgaccgcaatgaattggtattacacgtcaggaagc ggggacgtgaaatcagccggcaagcgccagtcgaaccgcggcgtggcgccggacg caatgtgcggcaatgccgtgatgtatgacgcggtcaaaggcaagatcctgacatt tgggggagtccggactacaccgacagtgacgcgacaaccaatgcccacattatta cccttggggagccggggacgagcccgaacacggtcttcgcgtccaatggcctcta tttcgcgcgtacctttcatacgtcggtggtcctgccggacggatcaacctttatc accggcggacagcgccgtggcatccccttcgaagactcgacccccgtctttacac cggagatttatgtgccggaacaggacacgttttataaacagaatccgaactcgat tgtacgcgcgtatcactccatcagccttcttctcccggacggacgtgtctttaat ggcggaggaggactgtgcggggactgcacgaccaatcattttgacgcgcagatct ttaccccgaattatctgtatgattcaaatgggaatctcgcgacccgtccgaaaat tacccgtacatcaacccagtccgtcaaagtgggcggccgcattacgatcagtacc gacagcagcattaccaaagcgtcactgattcgttacggcaccgcaacccatacag tcaacacggaccagcgccgtattccgttaaccctgaccaataacggtggcaattc gtatagcttccaggtaccgtcggactcgggcgtggcgctgccaggatactggatg ctgtttgtgatgaatagcgcgggcgtcccgagcgtagcgagcacgatccgtgtga cccaggccgcagcttgataa 92 GOh2014 MGSSHHHHHHSSGLVPRGSHMGTASAPIGSAIPRNNWAVTCDSAQSGNECNKAID GNKDTFWHTFYGANGDPKPPHTYTIDMKTTQNVNGLSVLPRQDGNQNGWIGRHEV YLSSDGTNWGSPVASGSWFADSTTKYSNFETRPARYVRLVAVTEANGQPWTSIAE INVFQASSYTAPQPGLGRWGPTIDLPIVPAAAAIEPTSGRVLMWSSYRNDAAEGS PGGITLTSSWDPSTGIVSDRTVTVTKHDMFCPGISMDGNGQIVVTGGWDAKKTSL YDSSSDSWIPGPDMQVARGYQSSATMSDGRVFTIGGSFSGGVFEKNGEVYSPSSK TWTSLPNAKVWPMLTADKQGLYMSDNHAWLFGWKKGSVFQAGPSTAMNWYYTSGS GDVKSAGKRQSNRGVAPDAMCGNAVMYDAVKGKILTFGGSPDYTDSDATTNAHII TLGEPGTSPNTVFASNGLYFARTFHTSVVLPDGSTFITGGQRRGIPFEDSTPVFT PEIYVPEQDTFYKQNPNSIVRAYHSISLLLPDGRVFNGGGGLCGDCTTNHFDAQI FTPNYLYDSNGNLATRPKITRTSTQSVKVGGRITISTDSSITKASLIRYGTATHT VNTDQRRIPLTLTNNGGNSYSFQVPSDSGVALPGYWMLFVMNSAGVPSVASTIRV TQAAA 93 GOh2015 atgggcagcagccatcatcatcatcatcacagcagcggcctggtgccgcgcggca gccatatgggtaccgcctctgcccctatcggctcagccatcccgcgcaataactg ggccgtaacgtgcgacagcgcgcagagcggcaacgagtgcaataaagccatcgac ggcaataaagacaccttctggcacacgttttatggcgcaaatggcgacccgaagc caccgcatacctataccattgacatgaaaaccacccagaatgtgaacgggctgtc cgtgctgccgcgccaggacggcaatcagaacggatggatcggccgtcacgaggta tatttaagctccgacggcaccaactggggatccccggtcgcgtcgggcagctggt tcgccgacagcaccaccaagtattccaattttgaaacccgtcctgcacgctacgt gcgcttagtggccgtgacagaggcgaacggccagccatggacctcaatcgccgaa atcaatgtattccaagccagctcctataccgcgccgcagccaggacttgggcgtt ggggcccgaccatcgacctgcctatcgtacccgcagcctgtgcgattgaaccaac gtcaggccgcgtactgatgtggagcagctaccgtaacgacgcggcggaaggcagc ccgggcggcatcactctgacgtcgagttgggatccatccacgggcatcgtctccg accgcaccgtgaccgtcacgaaacacgacatgttttgcccggggatcagcatgga cggcaacggccagatcgtcgtcacgggcggctgggacgccaagaagacgagcctc tatgacagtagcagcgacagttggatcccggggccggacatgcaggtggcacgcg ggtaccagtccagcgcgaccatgtcagacggccgtgtctttacaatcggcggctc atttagtggcggagtgtttgagaagaatggcgaagtctatagcccctcatccaaa acgtggacgtcacttccgaacgcgaaggtgaatcccatgttaaccgccgacaaac agggcctgtacatgagcgacaaccatgcgtggctgttcggctggaagaaggggag cgtctttcaggcgggcccgtcgaccgcaatgaattggtattacacgtcaggaagc ggggacgtgaaatcagccggcaagcgccagtcgaaccgcggcgtggcgccggacg caatgtgcggcaatgccgtgatgtatgacgcggtcaaaggcaagatcctgacatt tggcgggagtccggactacaccgacagtgacgcgacaaccaatgcccacattatt acccttggggagccggggacgagcccgaacacggtcttcgcgtccaatggcctct atttcgcgcgtacctttcatacgtcggtggtcctgccggacggatcaacctttat caccggcggacagcgccgtggcatccccttcgaagactcgacccccgtctttaca ccggagatttatgtgccggaacaggacacgttttataaacagaatccgaactcga ttgtacgcgcgtatcactccatcagccttcttctcccggacggacgtgtctttaa tggcggaggaggactgtgcggggactgcacgaccaatcattttgacgcgcagatc tttaccccgaattatctgtatgattcaaatgggaatctcgcgacccgtccgaaaa ttacccgtacatcaacccagtccgtcaaagtgggcggccgcattacgatcagtac cgacagcagcattaccaaagcgtcactgattcgttacggcaccgcaacccataca gtcaacacggaccagcgccgtattccgttaaccctgaccaataacggtggcaatt cgtatagcttccaggtaccgtcggactcgggcgtggcgctgccaggatactggat gctgtttgtgatgaatagcgcgggcgtcccgagcgtagcgagcacgatccgtgtg acccaggccgcagcttgataa 94 GOh2015 MGSSHHHHHHSSGLVPRGSHMGTASAPIGSAIPRNNWAVTCDSAQSGNECNKAID GNKDTFWHTFYGANGDPKPPHTYTIDMKTTQNVNGLSVLPRQDGNQNGWIGRHEV YLSSDGTNWGSPVASGSWFADSTTKYSNFETRPARYVRLVAVTEANGQPWTSIAE INVFQASSYTAPQPGLGRWGPTIDLPIVPAACAIEPTSGRVLMWSSYRNDAAEGS PGGITLTSSWDPSTGIVSDRTVTVTKHDMFCPGISMDGNGQIVVTGGWDAKKTSL YDSSSDSWIPGPDMQVARGYQSSATMSDGRVFTIGGSFSGGVFEKNGEVYSPSSK TWTSLPNAKVNPMLTADKQGLYMSDNHAWLFGWKKGSVFQAGPSTAMNWYYTSGS GDVKSAGKRQSNRGVAPDAMCGNAVMYDAVKGKILTFGGSPDYTDSDATTNAHII TLGEPGTSPNTVFASNGLYFARTFHTSVVLPDGSTFITGGQRRGIPFEDSTPVFT PEIYVPEQDTFYKQNPNSIVRAYHSISLLLPDGRVFNGGGGLCGDCTTNHFDAQI FTPNYLYDSNGNLATRPKITRTSTQSVKVGGRITISTDSSITKASLIRYGTATHT VNTDQRRIPLTLTNNGGNSYSFQVPSDSGVALPGYWMLFVMNSAGVPSVASTIRV TQAAA 95 GOh2016 atgggcagcagccatcatcatcatcatcacagcagcggcctggtgccgcgcggca gccatatgggtaccgcctctgcccctatcggctcagccatcccgcgcaataactg ggccgtaacgtgcgacagcgcgcagagcggcaacgagtgcaataaagccatcgac ggcaataaagacaccttctggcacacgttttatggcgcaaatggcgacccgaagc caccgcatacctataccattgacatgaaaaccacccagaatgtgaacgggctgtc cgtgctgccgcgccaggacggcaatcagaacggatggatcggccgtcacgaggta tatttaagctccgacggcaccaactggggatccccggtcgcgtcgggcagctggt tcgccgacagcaccaccaagtattccaattttgaaacccgtcctgcacgctacgt gcgcttagtggccgtgacagaggcgaacggccagccatggacctcaatcgccgaa atcaatgtattccaagccagctcctataccgcgccgcagccaggacttgggcgtt ggggcccgaccatcgacctgcctatcgtacccgcagccgcggcgattgaaccaac gtcaggccgcgtactgatgtggagcagctaccgtaacgacgcggcggaaggcagc ccgggcggcatcactctgacgtcgagttgggatccatccacgggcatcgtctccg acggtaccgtgaccgtcacgaaacacgacatgttttgcccggggatcagcatgga cggcaacggccagatcgtcgtcacgggcggctgggacgccaagaagacgagcctc tatgacagtagcagcgacagttggatcccggggccggacatgcaggtggcacgcg ggtaccagtccagcgcgaccatgtcagacggccgtgtctttacaatcggcggctc atttagtggcggagtgtttgagaagaatggcgaagtctatagcccctcatccaaa acgtggacgtcacttccgaacgcgaaggtgaatcccatgttaaccgccgacaaac agggcctgtacatgagcgacaaccatgcgtggctgttcggctggaagaaggggag cgtctttcaggcgggcccgtcgaccgcaatgaattggtattacacgtcaggaagc ggggacgtgaaatcagccggcaagcgccagtcgaaccgcggcgtggcgccggacg caatgtgcggcaatgccgtgatgtatgacgcggtcaaaggcaagatcctgacatt tggcgggagtccggactacaccgacagtgacgcgacaaccaatgcccacattatt acccttggggagccggggacgagcccgaacacggtcttcgcgtccaatggcctct atttcgcgcgtacctttcatacgtcggtggtcctgccggacggatcaacctttat caccggcggacagcgccgtggcatccccttcgaagactcgacccccgtctttaca ccggagatttatgtgccggaacaggacacgttttataaacagaatccgaactcga ttgtacgcgcgtatcactccatcagccttcttctcccggacggacgtgtctttaa tggcggaggaggactgtgcggggactgcacgaccaatcattttgacgcgcagatc tttaccccgaattatctgtatgattcaaatgggaatctcgcgacccgtccgaaaa ttacccgtacatcaacccagtccgtcaaagtgggcggccgcattacgatcagtac cgacagcagcattaccaaagcgtcactgattcgttacggcaccgcaacccataca gtcaacacggaccagcgccgtattccgttaaccctgaccaataacggtggcaatt cgtatagcttccaggtaccgtcggactcgggcgtggcgctgccaggatactggat gctgtttgtgatgaatagcgcgggcgtcccgagcgtagcgagcacgatccgtgtg acccaggccgcagcttgataa 96 GOh2016 MGSSHHHHHHSSGLVPRGSHMGTASAPIGSAIPRNNWAVTCDSAQSGNECNKAID GNKDTFWHTFYGANGDPKPPHTYTIDMKTTQNVNGLSVLPRQDGNQNGWIGRHEV YLSSDGTNWGSPVASGSWFADSTTKYSNFETRPARYVRLVAVTEANGQPWTSIAE INVFQASSYTAPQPGLGRWGPTIDLPIVPAAAAIEPTSGRVLMWSSYRNDAAEGS PGGITLTSSWDPSTGIVSDGTVTVTKHDMFCPGISMDGNGQIVVTGGWDAKKTSL YDSSSDSWIPGPDMQVARGYQSSATMSDGRVFTIGGSFSGGVFEKNGEVYSPSSK TWTSLPNAKVNPMLTADKQGLYMSDNHAWLFGWKKGSVFQAGPSTAMNWYYTSGS GDVKSAGKRQSNRGVAPDAMCGNAVMYDAVKGKILTFGGSPDYTDSDATTNAHII TLGEPGTSPNTVFASNGLYFARTFHTSVVLPDGSTFITGGQRRGIPFEDSTPVFT PEIYVPEQDTFYKQNPNSIVRAYHSISLLLPDGRVFNGGGGLCGDCTTNHFDAQI FTPNYLYDSNGNLATRPKITRTSTQSVKVGGRITISTDSSITKASLIRYGTATHT VNTDQRRIPLTLTNNGGNSYSFQVPSDSGVALPGYWMLFVMNSAGVPSVASTIRV TQAAA 97 GOh2017 atgggcagcagccatcatcatcatcatcacagcagcggcctggtgccgcgcggca gccatatgggtaccgcctctgcccctatcggctcagccatcccgcgcaataactg ggccgtaacgtgcgacagcgcgcagagcggcaacgagtgcaataaagccatcgac ggcaataaagacaccttctggcacacgttttatggcgcaaatggcgacccgaagc caccgcatacctataccattgacatgaaaaccacccagaatgtgaacgggctgtc cgtgctgccgcgccaggacggcaatcagaacggatggatcggccgtcacgaggta tatttaagctccgacggcaccaactggggatccccggtcgcgtcgggcagctggt tcgccgacagcaccaccaagtattccaattttgaaacccgtcctgcacgctacgt gcgcttagtggccgtgacagaggcgaacggccagccatggacctcaatcgccgaa atcaatgtattccaagccagctcctataccgcgccgcagccaggacttgggcgtt ggggcccgaccatcgacctgcctatcgtacccgcagccgcgattattgaaccaac gtcaggccgcgtactgatgtggagcagctaccgtaacgacgcggcggaaggcagc ccgggcggcatcactctgacgtcgagttgggatccatccacgggcatcgtctccg accgcaccgtgaccgtcacgaaacacgacatgttttgcccggggatcagcatgga cggcaacggccagatcgtcgtcacgggcggctgggacgccaagaagacgagcctc tatgacagtagcagcgacagttggatcccggggccggacatgcaggtggcacgcg ggtaccagtccagcgcgaccatgtcagacggccgtgtctttacaatcggcggctc atttagtggcggagtgtttgagaagaatggcgaagtctatagcccctcatccaaa acgtggacgtcacttccgaacgcgaaggtgaatcccatgttaaccgccgacaaac agggcctgtacatgagcgacaaccatgcgtggctgttcggctggaagaaggggag cgtctttcaggcgggcccgtcgaccgcaatgaattggtattacacgtcaggaagc ggggacgtgaaatcagccggcaagcgccagtcgaaccgcggcgtggcgccggacg caatgtgcggcaatgccgtgatgtatgacgcggtcaaaggcaagatcctgacatt tggcgggagtccggactacaccgacagtgacgcgacaaccaatgcccacattatt acccttggggagccggggacgagcccgaacacggtcttcgcgtccaatggcctct atttcgcgcgtacctttcatacgtcggtggtcctgccggacggatcaacctttat caccggcggacagcgccgtggcatccccttcgaagactcgacccccgtctttaca ccggagatttatgtgccggaacaggacacgttttataaacagaatccgaactcga ttgtacgcgcgtatcactccatcagccttcttctcccggacggacgtgtctttaa tggcggaggaggactgtgcggggactgcacgaccaatcattttgacgcgcagatc tttaccccgaattatctgtatgattcaaatgggaatctcgcgacccgtccgaaaa ttacccgtacatcaacccagtccgtcaaagtgggcggccgcattacgatcagtac cgacagcagcattaccaaagcgtcactgattcgttacggcaccgcaacccataca gtcaacacggaccagcgccgtattccgttaaccctgaccaataacggtggcaatt cgtatagcttccaggtaccgtcggactcgggcgtggcgctgccaggatactggat gctgtttgtgatgaatagcgcgggcgtcccgagcgtagcgagcacgatccgtgtg acccaggccgcagcttgataa 98 GOh2017 MGSSHHHHHHSSGLVPRGSHMGTASAPIGSAIPRNNWAVTCDSAQSGNECNKAID GNKDTFWHTFYGANGDPKPPHTYTIDMKTTQNVNGLSVLPRQDGNQNGWIGRHEV YLSSDGTNWGSPVASGSWFADSTTKYSNFETRPARYVRLVAVTEANGQPWTSIAE INVFQASSYTAPQPGLGRWGPTIDLPIVPAAAIIEPTSGRVLMWSSYRNDAAEGS PGGITLTSSWDPSTGIVSDRTVTVTKHDMFCPGISMDGNGQIVVTGGWDAKKTSL YDSSSDSWIPGPDMQVARGYQSSATMSDGRVFTIGGSFSGGVFEKNGEVYSPSSK TWTSLPNAKVNPMLTADKQGLYMSDNHAWLFGWKKGSVFQAGPSTAMNWYYTSGS GDVKSAGKRQSNRGVAPDAMCGNAVMYDAVKGKILTFGGSPDYTDSDATTNAHII TLGEPGTSPNTVFASNGLYFARTFHTSVVLPDGSTFITGGQRRGIPFEDSTPVFT PEIYVPEQDTFYKQNPNSIVRAYHSISLLLPDGRVFNGGGGLCGDCTTNHFDAQI FTPNYLYDSNGNLATRPKITRTSTQSVKVGGRITISTDSSITKASLIRYGTATHT VNTDQRRIPLTLTNNGGNSYSFQVPSDSGVALPGYWMLFVMNSAGVPSVASTIRV TQAAA 99 GOh2018 atgggcagcagccatcatcatcatcatcacagcagcggcctggtgccgcgcggca gccatatgggtaccgcctctgcccctatcggctcagccatcccgcgcaataactg ggccgtaacgtgcgacagcgcgcagagcggcaacgagtgcaataaagccatcgac ggcaataaagacaccttctggcacacgttttatggcgcaaatggcgacccgaagc caccgcatacctataccattgacatgaaaaccacccagaatgtgaacgggctgtc cgtgctgccgcgccaggacggcaatcagaacggatggatcggccgtcacgaggta tatttaagctccgacggcaccaactggggatccccggtcgcgtcgggcagctggt tcgccgacagcaccaccaagtattccaattttgaaacccgtcctgcacgctacgt gcgcttagtggccgtgacagaggcgaacggccagccatggacctcaatcgccgaa atcaatgtattccaagccagctcctataccgcgccgcagccaggacttggggttg gggcccgaccatcgacctgcctatcgtacccgcagccgcggcgattgaaccaacg tcaggccgcgtactgatgtggagcagctaccgtaacgacgcggcggaaggcagcc cgggcggcatcactctgacgtcgagttgggatccatccacgggcatcgtctccga ccgcaccgtgaccgtcacgaaacacgacatgttttgcccggggatcagcatggac ggcaacggccagatcgtcgtcacgggcggctgggacgccaagaagacgagcctct atgacagtagcagcgacagttggatcccggggccggacatgcaggtggcacgcgg gtaccagtccagcgcgaccatgtcagacggccgtgtctttacaatcggcggctca tttagtggcggagtgtttgagaagaatggcgaagtctatagcccctcatccaaaa cgtggacgtcacttccgaacgcgaaggtgaatcccatgttaaccgccgacagcca gggcctgtacatgagcgacaaccatgcgtggctgttcggctggaagaaggggagc gtctttcaggcgggcccgtcgaccgcaatgaattggtattacacgtcaggaagcg gggacgtgaaatcagccggcaagcgccagtcgaaccgcggcgtggcgccggacgc aatgtgcggcaatgccgtgatgtatgacgcggtcaaaggcaagatcctgacattt ggcgggagtccggactacaccgacagtgacgcgacaaccaatgcccacattatta cccttggggagccggggacgagcccgaacacggtcttcgcgtccaatggcctcta tttcgcgcgtacctttcatacgtcggtggtcctgccggacggatcaacctttatc accggcggacagcgccgtggcatccccttcgaagactcgacccccgtctttacac cggagatttatgtgccggaacaggacacgttttataaacagaatccgaactcgat tgtacgcgcgtatcactccatcagccttcttctcccggacggacgtgtctttaat ggcggaggaggactgtgcggggactgcacgaccaatcattttgacgcgcagatct ttaccccgaattatctgtatgattcaaatgggaatctcgcgacccgtccgaaaat tacccgtacatcaacccagtccgtcaaagtgggcggccgcattacgatcagtacc gacagcagcattaccaaagcgtcactgattcgttacggcaccgcaacccatacag tcaacacggaccagcgccgtattccgttaaccctgaccaataacggtggcaattc gtatagcttccaggtaccgtcggactcgggcgtggcgctgccaggatactggatg ctgtttgtgatgaatagcgcgggcgtcccgagcgtagcgagcacgatccgtgtga cccaggccgcagcttgataa 100 GOh2018 MGSSHHHHHHSSGLVPRGSHMGTASAPIGSAIPRNNWAVTCDSAQSGNECNKAID GNKDTFWHTFYGANGDPKPPHTYTIDMKTTQNVNGLSVLPRQDGNQNGWIGRHEV YLSSDGTNWGSPVASGSWFADSTTKYSNFETRPARYVRLVAVTEANGQPWTSIAE INVFQASSYTAPQPGLGRWGPTIDLPIVPAAAAIEPTSGRVLMWSSYRNDAAEGS PGGITLTSSWDPSTGIVSDRTVTVTKHDMFCPGISMDGNGQIVVTGGWDAKKTSL YDSSSDSWIPGPDMQVARGYQSSATMSDGRVFTIGGSFSGGVFEKNGEVYSPSSK TWTSLPNAKVNPMLTADSQGLYMSDNHAWLFGWKKGSVFQAGPSTAMNWYYTSGS GDVKSAGKRQSNRGVAPDAMCGNAVMYDAVKGKILTFGGSPDYTDSDATTNAHII TLGEPGTSPNTVFASNGLYFARTFHTSVVLPDGSTFITGGQRRGIPFEDSTPVFT PEIYVPEQDTFYKQNPNSIVRAYHSISLLLPDGRVFNGGGGLCGDCTTNHFDAQI FTPNYLYDSNGNLATRPKITRTSTQSVKVGGRITISTDSSITKASLIRYGTATHT VNTDQRRIPLTLTNNGGNSYSFQVPSDSGVALPGYWMLFVMNSAGVPSVASTIRV TQAAA 101 GOh2019 atgggcagcagccatcatcatcatcatcacagcagcggcctggtgccgcgcggca gccatatgggtaccgcctctgcccctatcggctcagccatcccgcgcaataactg ggccgtaacgtgcgacagcgcgcagagcggcaacgagtgcaataaagccatcgac ggcaataaagacaccttctggcacacgttttatggcgcaaatggcgacccgaagc caccgcatacctataccattgacatgaaaaccacccagaatgtgaacgggctgtc cgtgctgccgcgccaggacggcaatcagaacggatggatcggccgtcacgaggta tatttaagctccgacggcaccaactggggatccccggtcgcgtcgggcagctggt tcgccgacagcaccaccaagtattccaattttgaaacccgtcctgcacgctacgt gcgcttagtggccgtgacagaggcgaacggccagccatggacctcaatcgccgaa atcaatgtattccaagccagctcctataccgcgccgcagccaggacttgggcgtt ggggcccgaccatcgacctgcctatcgtacccgcagccgcggcgattgaaccaga ttcaggccgcgtactgatgtggagcagctaccgtaacgacgcggcggaaggcagc ccgggcggcatcactctgacgtcgagttgggatccatccacgggcatcgtctccg accgcaccgtgaccgtcacgaaacacgacatgttttgcccggggatcagcatgga cggcaacggccagatcgtcgtcacgggcggctgggacgccaagaagacgagcctc tatgacagtagcagcgacagttggatcccggggccggacatgcaggtggcacgcg ggtaccagtccagcgcgaccatgtcagacggccgtgtctttacaatcggcggctc atttagtggcggagtgtttgagaagaatggcgaagtctatagcccctcatccaaa acgtggacgtcacttccgaacgcgaaggtgaatcccatgttaaccgccgacaaac agggcctgtacatgagcgacaaccatgcgtggctgttcggctggaagaaggggag cgtctttcaggcgggcccgtcgaccgcaatgaattggtattacacgtcaggaagc ggggacgtgaaatcagccggcaagcgccagtcgaaccgcggcgtggcgccggacg caatgtgcggcaatgccgtgatgtatgacgcggtcaaaggcaagatcctgacatt tggcgggagtccggactacaccgacagtgacgcgacaaccaatgcccacattatt acccttggggagccggggacgagcccgaacacggtcttcgcgtccaatggcctct atttcgcgcgtacctttcatacgtcggtggtcctgccggacggatcaacctttat caccggcggacagcgccgtggcatccccttcgaagactcgacccccgtctttaca ccggagatttatgtgccggaacaggacacgttttataaacagaatccgaactcga ttgtacgcgcgtatcactccatcagccttcttctcccggacggacgtgtctttaa tggcggaggaggactgtgcggggactgcacgaccaatcattttgacgcgcagatc tttaccccgaattatctgtatgattcaaatgggaatctcgcgacccgtccgaaaa ttacccgtacatcaacccagtccgtcaaagtgggcggccgcattacgatcagtac cgacagcagcattaccaaagcgtcactgattcgttacggcaccgcaacccataca gtcaacacggaccagcgccgtattccgttaaccctgaccaataacggtggcaatt cgtatagcttccaggtaccgtcggactcgggcgtggcgctgccaggatactggat gctgtttgtgatgaatagcgcgggcgtcccgagcgtagcgagcacgatccgtgtg acccaggccgcagcttgataa 102 GOh2019 MGSSHHHHHHSSGLVPRGSHMGTASAPIGSAIPRNNWAVTCDSAQSGNECNKAID GNKDTFWHTFYGANGDPKPPHTYTIDMKTTQNVNGLSVLPRQDGNQNGWIGRHEV YLSSDGTNWGSPVASGSWFADSTTKYSNFETRPARYVRLVAVTEANGQPWTSIAE INVFQASSYTAPQPGLGRWGPTIDLPIVPAAAAIEPDSGRVLMWSSYRNDAAEGS PGGITLTSSWDPSTGIVSDRTVTVTKHDMFCPGISMDGNGQIVVTGGWDAKKTSL YDSSSDSWIPGPDMQVARGYQSSATMSDGRVFTIGGSFSGGVFEKNGEVYSPSSK TWTSLPNAKVNPMLTADKQGLYMSDNHAWLFGWKKGSVFQAGPSTAMNWYYTSGS GDVKSAGKRQSNRGVAPDAMCGNAVMYDAVKGKILTFGGSPDYTDSDATTNAHII TLGEPGTSPNTVFASNGLYFARTFHTSVVLPDGSTFITGGQRRGIPFEDSTPVFT PEIYVPEQDTFYKQNPNSIVRAYHSISLLLPDGRVFNGGGGLCGDCTTNHFDAQI FTPNYLYDSNGNLATRPKITRTSTQSVKVGGRITISTDSSITKASLIRYGTATHT VNTDQRRIPLTLTNNGGNSYSFQVPSDSGVALPGYWMLFVMNSAGVPSVASTIRV TQAAA 103 GOh2020 atgggcagcagccatcatcatcatcatcacagcagcggcctggtgccgcgcggca gccatatgggtaccgcctctgcccctatcggctcagccatcccgcgcaataactg ggccgtaacgtgcgacagcgcgcagagcggcaacgagtgcaataaagccatcgac ggcaataaagacaccttctggcacacgttttatggcgcaaatggcgacccgaagc caccgcatacctataccattgacatgaaaaccacccagaatgtgaacgggctgtc cgtgctgccgcgccaggacggcaatcagaacggatggatcggccgtcacgaggta tatttaagctccgacggcaccaactggggatccccggtcgcgtcgggcagctggt tcgccgacagcaccaccaagtattccaattttgaaacccgtcctgcacgctacgt gcgcttagtggccgtgacagaggcgaacggccagccatggacctcaatcgccgaa atcaatgtattccaagccagctcctataccgcgccgcagccaggacttgggcgtt ggggcccgaccatcgacctgcctatcgtacccgcagccgcggcgattgaaccaca gtcaggccgcgtactgatgtggagcagctaccgtaacgacgcggcggaaggcagc ccgggcggcatcactctgacgtcgagttgggatccatccacgggcatcgtctccg accgcaccgtgaccgtcacgaaacacgacatgttttgcccggggatcagcatgga cggcaacggccagatcgtcgtcacgggcggctgggacgccaagaagacgagcctc tatgacagtagcagcgacagttggatcccggggccggacatgcaggtggcacgcg ggtaccagtccagcgcgaccatgtcagacggccgtgtctttacaatcggcggctc atttagtggcggagtgtttgagaagaatggcgaagtctatagcccctcatccaaa acgtggacgtcacttccgaacgcgaaggtgaatcccatgttaaccgccgacaaac agggcctgtacatgagcgacaaccatgcgtggctgttcggctggaagaaggggag cgtctttcaggcgggcccgtcgaccgcaatgaattggtattacacgtcaggaagc ggggacgtgaaatcagccggcaagcgccagtcgaaccgcggcgtggcgccggacg caatgtgcggcaatgccgtgatgtatgacgcggtcaaaggcaagatcctgacatt tggcgggagtccggactacaccgacagtgacgcgacaaccaatgcccacattatt acccttggggagccggggacgagcccgaacacggtcttcgcgtccaatggcctct atttcgcgcgtacctttcatacgtcggtggtcctgccggacggatcaacctttat caccggcggacagcgccgtggcatccccttcgaagactcgacccccgtctttaca ccggagatttatgtgccggaacaggacacgttttataaacagaatccgaactcga ttgtacgcgcgtatcactccatcagccttcttctcccggacggacgtgtctttaa tggcggaggaggactgtgcggggactgcacgaccaatcattttgacgcgcagatc tttaccccgaattatctgtatgattcaaatgggaatctcgcgacccgtccgaaaa ttacccgtacatcaacccagtccgtcaaagtgggcggccgcattacgatcagtac cgacagcagcattaccaaagcgtcactgattcgttacggcaccgcaacccataca gtcaacacggaccagcgccgtattccgttaaccctgaccaataacggtggcaatt cgtatagcttccaggtaccgtcggactcgggcgtggcgctgccaggatactggat gctgtttgtgatgaatagcgcgggcgtcccgagcgtagcgagcacgatccgtgtg acccaggccgcagcttgataa 104 GOh2020 MGSSHHHHHHSSGLVPRGSHMGTASAPIGSAIPRNNWAVTCDSAQSGNECNKAID GNKDTFWHTFYGANGDPKPPHTYTIDMKTTQNVNGLSVLPRQDGNQNGWIGRHEV YLSSDGTNWGSPVASGSWFADSTTKYSNFETRPARYVRLVAVTEANGQPWTSIAE INVFQASSYTAPQPGLGRWGPTIDLPIVPAAAAIEPQSGRVLMWSSYRNDAAEGS PGGITLTSSWDPSTGIVSDRTVTVTKHDMFCPGISMDGNGQIVVTGGWDAKKTSL YDSSSDSWIPGPDMQVARGYQSSATMSDGRVFTIGGSFSGGVFEKNGEVYSPSSK TWTSLPNAKVNPMLTADKQGLYMSDNHAWLFGWKKGSVFQAGPSTAMNWYYTSGS GDVKSAGKRQSNRGVAPDAMCGNAVMYDAVKGKILTFGGSPDYTDSDATTNAHII TLGEPGTSPNTVFASNGLYFARTFHTSVVLPDGSTFITGGQRRGIPFEDSTPVFT PEIYVPEQDTFYKQNPNSIVRAYHSISLLLPDGRVFNGGGGLCGDCTTNHFDAQI FTPNYLYDSNGNLATRPKITRTSTQSVKVGGRITISTDSSITKASLIRYGTATHT VNTDQRRIPLTLTNNGGNSYSFQVPSDSGVALPGYWMLFVMNSAGVPSVASTIRV TQAAA 105 GOh2021 atgggcagcagccatcatcatcatcatcacagcagcggcctggtgccgcgcggca gccatatgggtaccgcctctgcccctatcggctcagccatcccgcgcaataactg ggccgtaacgtgcgacagcgcgcagagcggcaacgagtgcaataaagccatcgac ggcaataaagacaccttctggcacacgttttatggcgcaaatggcgacccgaagc caccgcatacctataccattgacatgaaaaccacccagaatgtgaacgggctgtc cgtgctgccgcgccaggacggcaatcagaacggatggatcggccgtcacgaggta tatttaagctccgacggcaccaactggggatccccggtcgcgtcgggcagctggt tcgccgacagcaccaccaagtattccaattttgaaacccgtcctgcacgctacgt gcgcttagtggccgtgacagaggcgaacggccagccatggacctcaatcgccgaa atcaatgtattccaagccagctcctataccgcgccgcagccaggacttgggcgtt ggggcccgaccatcgacctgcctatcgtacccgcagccgcggcgattgaaccaat ttcaggccgcgtactgatgtggagcagctaccgtaacgacgcggcggaaggcagc ccgggcggcatcactctgacgtcgagttgggatccatccacgggcatcgtctccg accgcaccgtgaccgtcacgaaacacgacatgttttgcccggggatcagcatgga cggcaacggccagatcgtcgtcacgggcggctgggacgccaagaagacgagcctc tatgacagtagcagcgacagttggatcccggggccggacatgcaggtggcacgcg ggtaccagtccagcgcgaccatgtcagacggccgtgtctttacaatcggcggctc atttagtggcggagtgtttgagaagaatggcgaagtctatagcccctcatccaaa acgtggacgtcacttccgaacgcgaaggtgaatcccatgttaaccgccgacaaac agggcctgtacatgagcgacaaccatgcgtggctgttcggctggaagaaggggag cgtctttcaggcgggcccgtcgaccgcaatgaattggtattacacgtcaggaagc ggggacgtgaaatcagccggcaagcgccagtcgaaccgcggcgtggcgccggacg caatgtgcggcaatgccgtgatgtatgacgcggtcaaaggcaagatcctgacatt tggcgggagtccggactacaccgacagtgacgcgacaaccaatgcccacattatt acccttggggagccggggacgagcccgaacacggtcttcgcgtccaatggcctct atttcgcgcgtacctttcatacgtcggtggtcctgccggacggatcaacctttat caccggcggacagcgccgtggcatccccttcgaagactcgacccccgtctttaca ccggagatttatgtgccggaacaggacacgttttataaacagaatccgaactcga ttgtacgcgcgtatcactccatcagccttcttctcccggacggacgtgtctttaa tggcggaggaggactgtgcggggactgcacgaccaatcattttgacgcgcagatc tttaccccgaattatctgtatgattcaaatgggaatctcgcgacccgtccgaaaa ttacccgtacatcaacccagtccgtcaaagtgggcggccgcattacgatcagtac cgacagcagcattaccaaagcgtcactgattcgttacggcaccgcaacccataca gtcaacacggaccagcgccgtattccgttaaccctgaccaataacggtggcaatt cgtatagcttccaggtaccgtcggactcgggcgtggcgctgccaggatactggat gctgtttgtgatgaatagcgcgggcgtcccgagcgtagcgagcacgatccgtgtg acccaggccgcagcttgataa 106 GOh2021 MGSSHHHHHHSSGLVPRGSHMGTASAPIGSAIPRNNWAVTCDSAQSGNECNKAID GNKDTFWHTFYGANGDPKPPHTYTIDMKTTQNVNGLSVLPRQDGNQNGWIGRHEV YLSSDGTNWGSPVASGSWFADSTTKYSNFETRPARYVRLVAVTEANGQPWTSIAE INVFQASSYTAPQPGLGRWGPTIDLPIVPAAAAIEPISGRVLMWSSYRNDAAEGS PGGITLTSSWDPSTGIVSDRTVTVTKHDMFCPGISMDGNGQIVVTGGWDAKKTSL YDSSSDSWIPGPDMQVARGYQSSATMSDGRVFTIGGSFSGGVFEKNGEVYSPSSK TWTSLPNAKVNPMLTADKQGLYMSDNHAWLFGWKKGSVFQAGPSTAMNWYYTSGS GDVKSAGKRQSNRGVAPDAMCGNAVMYDAVKGKILTFGGSPDYTDSDATTNAHII TLGEPGTSPNTVFASNGLYFARTFHTSVVLPDGSTFITGGQRRGIPFEDSTPVFT PEIYVPEQDTFYKQNPNSIVRAYHSISLLLPDGRVFNGGGGLCGDCTTNHFDAQI FTPNYLYDSNGNLATRPKITRTSTQSVKVGGRITISTDSSITKASLIRYGTATHT VNTDQRRIPLTLTNNGGNSYSFQVPSDSGVALPGYWMLFVMNSAGVPSVASTIRV TQAAA 107 GOh2022 atgggcagcagccatcatcatcatcatcacagcagcggcctggtgccgcgcggca gccatatgggtaccgcctctgcccctatcggctcagccatcccgcgcaataactg ggccgtaacgtgcgacagcgcgcagagcggcaacgagtgcaataaagccatcgac ggcaataaagacaccttctggcacacgttttatggcgcaaatggcgacccgaagc caccgcatacctataccattgacatgaaaaccacccagaatgtgaacgggctgtc cgtgctgccgcgccaggacggcaatcagaacggatggatcggccgtcacgaggta tatttaagctccgacggcaccaactggggatccccggtcgcgtcgggcagctggt tcgccgacagcaccaccaagtattccaattttgaaacccgtcctgcacgctacgt gcgcttagtggccgtgacagaggcgaacggccagccatggacctcaatcgccgaa atcaatgtattccaagccagctcctataccgcgccgcagccaggacttgggcgtt ggggcccgaccatcgacctgcctatcgtacccgcagccgcggcgattgaaccaaa atcaggccgcgtactgatgtggagcagctaccgtaacgacgcggcggaaggcagc ccgggcggcatcactctgacgtcgagttgggatccatccacgggcatcgtctccg accgcaccgtgaccgtcacgaaacacgacatgttttgcccggggatcagcatgga cggcaacggccagatcgtcgtcacgggcggctgggacgccaagaagacgagcctc tatgacagtagcagcgacagttggatcccggggccggacatgcaggtggcacgcg ggtaccagtccagcgcgaccatgtcagacggccgtgtctttacaatcggcggctc atttagtggcggagtgtttgagaagaatggcgaagtctatagcccctcatccaaa acgtggacgtcacttccgaacgcgaaggtgaatcccatgttaaccgccgacaaac agggcctgtacatgagcgacaaccatgcgtggctgttcggctggaagaaggggag cgtctttcaggcgggcccgtcgaccgcaatgaattggtattacacgtcaggaagc ggggacgtgaaatcagccggcaagcgccagtcgaaccgcggcgtggcgccggacg caatgtgcggcaatgccgtgatgtatgacgcggtcaaaggcaagatcctgacatt tggcgggagtccggactacaccgacagtgacgcgacaaccaatgcccacattatt acccttggggagccggggacgagcccgaacacggtcttcgcgtccaatggcctct atttcgcgcgtacctttcatacgtcggtggtcctgccggacggatcaacctttat caccggcggacagcgccgtggcatccccttcgaagactcgacccccgtctttaca ccggagatttatgtgccggaacaggacacgttttataaacagaatccgaactcga ttgtacgcgcgtatcactccatcagccttcttctcccggacggacgtgtctttaa tggcggaggaggactgtgcggggactgcacgaccaatcattttgacgcgcagatc tttaccccgaattatctgtatgattcaaatgggaatctcgcgacccgtccgaaaa ttacccgtacatcaacccagtccgtcaaagtgggcggccgcattacgatcagtac cgacagcagcattaccaaagcgtcactgattcgttacggcaccgcaacccataca gtcaacacggaccagcgccgtattccgttaaccctgaccaataacggtggcaatt cgtatagcttccaggtaccgtcggactcgggcgtggcgctgccaggatactggat gctgtttgtgatgaatagcgcgggcgtcccgagcgtagcgagcacgatccgtgtg acccaggccgcagcttgataa 108 GOh2022 MGSSHHHHHHSSGLVPRGSHMGTASAPIGSAIPRNNWAVTCDSAQSGNECNKAID GNKDTFWHTFYGANGDPKPPHTYTIDMKTTQNVNGLSVLPRQDGNQNGWIGRHEV YLSSDGTNWGSPVASGSWFADSTTKYSNFETRPARYVRLVAVTEANGQPWTSIAE INVFQASSYTAPQPGLGRWGPTIDLPIVPAAAAIEPKSGRVLMWSSYRNDAAEGS PGGITLTSSWDPSTGIVSDRTVTVTKHDMFCPGISMDGNGQIVVTGGWDAKKTSL YDSSSDSWIPGPDMQVARGYQSSATMSDGRVFTIGGSFSGGVFEKNGEVYSPSSK TWTSLPNAKVNPMLTADKQGLYMSDNHAWLFGWKKGSVFQAGPSTAMNWYYTSGS GDVKSAGKRQSNRGVAPDAMCGNAVMYDAVKGKILTFGGSPDYTDSDATTNAHII TLGEPGTSPNTVFASNGLYFARTFHTSVVLPDGSTFITGGQRRGIPFEDSTPVFT PEIYVPEQDTFYKQNPNSIVRAYHSISLLLPDGRVFNGGGGLCGDCTTNHFDAQI FTPNYLYDSNGNLATRPKITRTSTQSVKVGGRITISTDSSITKASLIRYGTATHT VNTDQRRIPLTLTNNGGNSYSFQVPSDSGVALPGYWMLFVMNSAGVPSVASTIRV TQAAA 109 GOh2023 atgggcagcagccatcatcatcatcatcacagcagcggcctggtgccgcgcggca gccatatgggtaccgcctctgcccctatcggctcagccatcccgcgcaataactg ggccgtaacgtgcgacagcgcgcagagcggcaacgagtgcaataaagccatcgac ggcaataaagacaccttctggcacacgttttatggcgcaaatggcgacccgaagc caccgcatacctataccattgacatgaaaaccacccagaatgtgaacgggctgtc cgtgctgccgcgccaggacggcaatcagaacggatggatcggccgtcacgaggta tatttaagctccgacggcaccaactggggatccccggtcgcgtcgggcagctggt tcgccgacagcaccaccaagtattccaattttgaaacccgtcctgcacgctacgt gcgcttagtggccgtgacagaggcgaacggccagccatggacctcaatcgccgaa atcaatgtattccaagccagctcctataccgcgccgcagccaggacttgggcgtt ggggcccgaccatcgacctgcctatcgtatgtgcagccgcggcgattgaaccaac gtcaggccgcgtactgatgtggagcagctaccgtaacgacgcggcggaaggcagc ccgggcggcatcactctgacgtcgagttgggatccatccacgggcatcgtctccg accgcaccgtgaccgtcacgaaacacgacatgttttgcccggggatcagcatgga cggcaacggccagatcgtcgtcacgggcggctgggacgccaagaagacgagcctc tatgacagtagcagcgacagttggatcccggggccggacatgcaggtggcacgcg ggtaccagtccagcgcgaccatgtcagacggccgtgtctttacaatcggcggctc atttagtggcggagtgtttgagaagaatggcgaagtctatagcccctcatccaaa acgtggacgtcacttccgaacgcgaaggtgaatcccatgttaaccgccgacaaac agggcctgtacatgagcgacaaccatgcgtggctgttcggctggaagaaggggag cgtctttcaggcgggcccgtcgaccgcaatgaattggtattacacgtcaggaagc ggggacgtgaaatcagccggcaagcgccagtcgaaccgcggcgtggcgccggacg caatgtgcggcaatgccgtgatgtatgacgcggtcaaaggcaagatcctgacatt tgggggagtccggactacaccgacagtgacgcgacaaccaatgcccacattatta cccttggggagccggggacgagcccgaacacggtcttcgcgtccaatggcctcta tttcgcgcgtacctttcatacgtcggtggtcctgccggacggatcaacctttatc accggcggacagcgccgtggcatccccttcgaagactcgacccccgtctttacac cggagatttatgtgccggaacaggacacgttttataaacagaatccgaactcgat tgtacgcgcgtatcactccatcagccttcttctcccggacggacgtgtctttaat ggcggaggaggactgtgcggggactgcacgaccaatcattttgacgcgcagatct ttaccccgaattatctgtatgattcaaatgggaatctcgcgacccgtccgaaaat tacccgtacatcaacccagtccgtcaaagtgggcggccgcattacgatcagtacc gacagcagcattaccaaagcgtcactgattcgttacggcaccgcaacccatacag tcaacacggaccagcgccgtattccgttaaccctgaccaataacggtggcaattc gtatagcttccaggtaccgtcggactcgggcgtggcgctgccaggatactggatg ctgtttgtgatgaatagcgcgggcgtcccgagcgtagcgagcacgatccgtgtga cccaggccgcagcttgataa 110 GOh2023 MGSSHHHHHHSSGLVPRGSHMGTASAPIGSAIPRNNWAVTCDSAQSGNECNKAID GNKDTFWHTFYGANGDPKPPHTYTIDMKTTQNVNGLSVLPRQDGNQNGWIGRHEV YLSSDGTNWGSPVASGSWFADSTTKYSNFETRPARYVRLVAVTEANGQPWTSIAE INVFQASSYTAPQPGLGRWGPTIDLPIVCAAAAIEPTSGRVLMWSSYRNDAAEGS PGGITLTSSWDPSTGIVSDRTVTVTKHDMFCPGISMDGNGQIVVTGGWDAKKTSL YDSSSDSWIPGPDMQVARGYQSSATMSDGRVFTIGGSFSGGVFEKNGEVYSPSSK TWTSLPNAKVNPMLTADKQGLYMSDNHAWLFGWKKGSVFQAGPSTAMNWYYTSGS GDVKSAGKRQSNRGVAPDAMCGNAVMYDAVKGKILTFGGSPDYTDSDATTNAHII TLGEPGTSPNTVFASNGLYFARTFHTSVVLPDGSTFITGGQRRGIPFEDSTPVFT PEIYVPEQDTFYKQNPNSIVRAYHSISLLLPDGRVFNGGGGLCGDCTTNHFDAQI FTPNYLYDSNGNLATRPKITRTSTQSVKVGGRITISTDSSITKASLIRYGTATHT VNTDQRRIPLTLTNNGGNSYSFQVPSDSGVALPGYWMLFVMNSAGVPSVASTIRV TQAAA 111 GOh2025 atgggcagcagccatcatcatcatcatcacagcagcggcctggtgccgcgcggca gccatatgggtaccgcctctgcccctatcggctcagccatcccgcgcaataactg ggccgtaacgtgcgacagcgcgcagagcggcaacgagtgcaataaagccatcgac ggcaataaagacaccttctggcacacgttttatggcgcaaatggcgacccgaagc caccgcatacctataccattgacatgaaaaccacccagaatgtgaacgggctgtc cgtgctgccgcgccaggacggcaatcagaacggatggatcggccgtcacgaggta tatttaagctccgacggcaccaactggggatccccggtcgcgtcgggcagctggt tcgccgacagcaccaccaagtattccaattttgaaacccgtcctgcacgctacgt gcgcttagtggccgtgacagaggcgaacggccagccatggacctcaatcgccgaa atcaatgtattccaagccagctcctataccgcgccgcagccaggacttgggcgtt ggggcccgaccatcgacctgcctatcgtacccgcagccgcggcgattgaaccaac gtcaggccgcgtactgatgtggagcagctaccgtaacgacgcggcggaaggcagc ccgggcggcatcactctgacgtcgagttgggatccatccacgggcatcgtctccg accgcaccgtgaccgtcacgaaacacgacatgttttgcccggggatcagcatgga cggcaacggccagatcgtcgtcacgggcggctgggacgccaagaagacgagcctc tatgacagtagcagcgacagttggatcccggggccggacatgcaggtggcacgcg ggtaccagtccagcgcgaccatgtcagacggccgtgtctttacaatcggcggctc atttagtggcggagtgtttgagaagaatggcgaagtctatagcccctcatccaaa acgtggacgtcacttccgaacgcgaaggtgaatcccatgttaaccctggacaaac agggcctgtacatgagcgacaaccatgcgtggctgttcggctggaagaaggggag cgtctttcaggcgggcccgtcgaccgcaatgaattggtattacacgtcaggaagc ggggacgtgaaatcagccggcaagcgccagtcgaaccgcggcgtggcgccggacg caatgtgcggcaatgccgtgatgtatgacgcggtcaaaggcaagatcctgacatt tggcgggagtccggactacaccgacagtgacgcgacaaccaatgcccacattatt acccttggggagccggggacgagcccgaacacggtcttcgcgtccaatggcctct atttcgcgcgtacctttcatacgtcggtggtcctgccggacggatcaacctttat caccggcggacagcgccgtggcatccccttcgaagactcgacccccgtctttaca ccggagatttatgtgccggaacaggacacgttttataaacagaatccgaactcga ttgtacgcgcgtatcactccatcagccttcttctcccggacggacgtgtctttaa tggcggaggaggactgtgcggggactgcacgaccaatcattttgacgcgcagatc tttaccccgaattatctgtatgattcaaatgggaatctcgcgacccgtccgaaaa ttacccgtacatcaacccagtccgtcaaagtgggcggccgcattacgatcagtac cgacagcagcattaccaaagcgtcactgattcgttacggcaccgcaacccataca gtcaacacggaccagcgccgtattccgttaaccctgaccaataacggtggcaatt cgtatagcttccaggtaccgtcggactcgggcgtggcgctgccaggatactggat gctgtttgtgatgaatagcgcgggcgtcccgagcgtagcgagcacgatccgtgtg acccaggccgcagcttgataa 112 GOh2025 MGSSHHHHHHSSGLVPRGSHMGTASAPIGSAIPRNNWAVTCDSAQSGNECNKAID GNKDTFWHTFYGANGDPKPPHTYTIDMKTTQNVNGLSVLPRQDGNQNGWIGRHEV YLSSDGTNWGSPVASGSWFADSTTKYSNFETRPARYVRLVAVTEANGQPWTSIAE INVFQASSYTAPQPGLGRWGPTIDLPIVPAAAAIEPTSGRVLMWSSYRNDAAEGS PGGITLTSSWDPSTGIVSDRTVTVTKHDMFCPGISMDGNGQIVVTGGWDAKKTSL YDSSSDSWIPGPDMQVARGYQSSATMSDGRVFTIGGSFSGGVFEKNGEVYSPSSK TWTSLPNAKVNPMLTLDKQGLYMSDNHAWLFGWKKGSVFQAGPSTAMNWYYTSGS GDVKSAGKRQSNRGVAPDAMCGNAVMYDAVKGKILTFGGSPDYTDSDATTNAHII TLGEPGTSPNTVFASNGLYFARTFHTSVVLPDGSTFITGGQRRGIPFEDSTPVFT PEIYVPEQDTFYKQNPNSIVRAYHSISLLLPDGRVFNGGGGLCGDCTTNHFDAQI FTPNYLYDSNGNLATRPKITRTSTQSVKVGGRITISTDSSITKASLIRYGTATHT VNTDQRRIPLTLTNNGGNSYSFQVPSDSGVALPGYWMLFVMNSAGVPSVASTIRV TQAAA 113 GOh2026 atgggcagcagccatcatcatcatcatcacagcagcggcctggtgccgcgcggca gccatatgggtaccgcctctgcccctatcggctcagccatcccgcgcaataactg ggccgtaacgtgcgacagcgcgcagagcggcaacgagtgcaataaagccatcgac ggcaataaagacaccttctggcacacgttttatggcgcaaatggcgacccgaagc caccgcatacctataccattgacatgaaaaccacccagaatgtgaacgggctgtc cgtgctgccgcgccaggacggcaatcagaacggatggatcggccgtcacgaggta tatttaagctccgacggcaccaactggggatccccggtcgcgtcgggcagctggt tcgccgacagcaccaccaagtattccaattttgaaacccgtcctgcacgctacgt gcgcttagtggccgtgacagaggcgaacggccagccatggacctcaatcgccgaa atcaatgtattccaagccagctcctataccgcgccgcagccaggacttgggcgtt ggggcccgaccatcgacctgcctatcgtacccgcagccgcggcgattgaaccaac gtcaggccgcgtactgatgtggagcagctaccgtaacgacgcggcggaaggcagc ccgggcggcatcactctgacgtcgagttgggatccatccacgggcatcgtctccg accgcaccgtgaccgtcacgaaacacgacatgttttgcccggggatcagcatgga cggcaacggccagatcgtcgtcacgggcggctgggacgccaagaagacgagcctc tatgacagtagcagcgacagttggatcccggggccggacatgcaggtggcacgcg ggtaccagtccagcgcgaccatgtcagacggccgtgtctttacaatcggcggctc atttagtggcggagtgtttgagaagaatggcgaagtctatagcccctcatccaaa acgtggacgtcacttccgaacgcgaaggtgaatcccatgttaaccgccgacaaac agggcctgtacatgagcgacaaccatgcgtggctgttcggctggaagaaggggag cgtctttcaggcgggcccgtcgaccgcaatgaattggtattacacgtcaggaagc ggggacgtgatctcagccggcaagcgccagtcgaaccgcggcgtggcgccggacg caatgtgcggcaatgccgtgatgtatgacgcggtcaaaggcaagatcctgacatt tggcgggagtccggactacaccgacagtgacgcgacaaccaatgcccacattatt acccttggggagccggggacgagcccgaacacggtcttcgcgtccaatggcctct atttcgcgcgtacctttcatacgtcggtggtcctgccggacggatcaacctttat caccggcggacagcgccgtggcatccccttcgaagactcgacccccgtctttaca ccggagatttatgtgccggaacaggacacgttttataaacagaatccgaactcga ttgtacgcgcgtatcactccatcagccttcttctcccggacggacgtgtctttaa tggcggaggaggactgtgcggggactgcacgaccaatcattttgacgcgcagatc tttaccccgaattatctgtatgattcaaatgggaatctcgcgacccgtccgaaaa ttacccgtacatcaacccagtccgtcaaagtgggcggccgcattacgatcagtac cgacagcagcattaccaaagcgtcactgattcgttacggcaccgcaacccataca gtcaacacggaccagcgccgtattccgttaaccctgaccaataacggtggcaatt cgtatagcttccaggtaccgtcggactcgggcgtggcgctgccaggatactggat gctgtttgtgatgaatagcgcgggcgtcccgagcgtagcgagcacgatccgtgtg acccaggccgcagcttgataa 114 GOh2026 MGSSHHHHHHSSGLVPRGSHMGTASAPIGSAIPRNNWAVTCDSAQSGNECNKAID GNKDTFWHTFYGANGDPKPPHTYTIDMKTTQNVNGLSVLPRQDGNQNGWIGRHEV YLSSDGTNWGSPVASGSWFADSTTKYSNFETRPARYVRLVAVTEANGQPWTSIAE INVFQASSYTAPQPGLGRWGPTIDLPIVPAAAAIEPTSGRVLMWSSYRNDAAEGS PGGITLTSSWDPSTGIVSDRTVTVTKHDMFCPGISMDGNGQIVVTGGWDAKKTSL YDSSSDSWIPGPDMQVARGYQSSATMSDGRVFTIGGSFSGGVFEKNGEVYSPSSK TWTSLPNAKVNPMLTADKQGLYMSDNHAWLFGWKKGSVFQAGPSTAMNWYYTSGS GDVISAGKRQSNRGVAPDAMCGNAVMYDAVKGKILTFGGSPDYTDSDATTNAHII TLGEPGTSPNTVFASNGLYFARTFHTSVVLPDGSTFITGGQRRGIPFEDSTPVFT PEIYVPEQDTFYKQNPNSIVRAYHSISLLLPDGRVFNGGGGLCGDCTTNHFDAQI FTPNYLYDSNGNLATRPKITRTSTQSVKVGGRITISTDSSITKASLIRYGTATHT VNTDQRRIPLTLTNNGGNSYSFQVPSDSGVALPGYWMLFVMNSAGVPSVASTIRV TQAAA 115 GOh2027 atgggcagcagccatcatcatcatcatcacagcagcggcctggtgccgcgcggca gccatatgggtaccgcctctgcccctatcggctcagccatcccgcgcaataactg ggccgtaacgtgcgacagcgcgcagagcggcaacgagtgcaataaagccatcgac ggcaataaagacaccttctggcacacgttttatggcgcaaatggcgacccgaagc caccgcatacctataccattgacatgaaaaccacccagaatgtgaacgggctgtc cgtgctgccgcgccaggacggcaatcagaacggatggatcggccgtcacgaggta tatttaagctccgacggcaccaactggggatccccggtcgcgtcgggcagctggt tcgccgacagcaccaccaagtattccaattttgaaacccgtcctgcacgctacgt gcgcttagtggccgtgacagaggcgaacggccagccatggacctcaatcgccgaa atcaatgtattccaagccagctcctataccgcgccgcagccaggacttgggcgtt ggggcccgaccatcgacctgcctatcgtacccgcagccgcggcgattgaaccaac gtcaggccgcgtactgatgtggagcagctaccgtaacgacgcggcggaaggcagc ccgggcggcatcactctgacgtcgagttgggatccatccacgggcatcgtctccg accgcaccgtgaccgtcacgaaacacgacatgttttgcccggggatcagcatgga cggcaacggccagatcgtcgtcacgggcggctgggacgccaagaagacgagcctc tatgacagtagcagcgacagttggatcccggggccggacatgcaggtggcacgcg ggtaccagtccagcgcgaccatgtcagacggccgtgtctttacaatcggcggctc atttagtggcggagtgtttgagaagaatggcgaagtctatagcccctcatccaaa acgtggacgtcacttccgaacgcgaaggtgaatcccatgttaaccgccgacaaac agggcctgtggatgagcgacaaccatgcgtggctgttcggctggaagaaggggag cgtctttcaggcgggcccgtcgaccgcaatgaattggtattacacgtcaggaagc ggggacgtgaaatcagccggcaagcgccagtcgaaccgcggcgtggcgccggacg caatgtgcggcaatgccgtgatgtatgacgcggtcaaaggcaagatcctgacatt tggcgggagtccggactacaccgacagtgacgcgacaaccaatgcccacattatt acccttggggagccggggacgagcccgaacacggtcttcgcgtccaatggcctct atttcgcgcgtacctttcatacgtcggtggtcctgccggacggatcaacctttat caccggcggacagcgccgtggcatccccttcgaagactcgacccccgtctttaca ccggagatttatgtgccggaacaggacacgttttataaacagaatccgaactcga ttgtacgcgcgtatcactccatcagccttcttctcccggacggacgtgtctttaa tggcggaggaggactgtgcggggactgcacgaccaatcattttgacgcgcagatc tttaccccgaattatctgtatgattcaaatgggaatctcgcgacccgtccgaaaa ttacccgtacatcaacccagtccgtcaaagtgggcggccgcattacgatcagtac cgacagcagcattaccaaagcgtcactgattcgttacggcaccgcaacccataca gtcaacacggaccagcgccgtattccgttaaccctgaccaataacggtggcaatt cgtatagcttccaggtaccgtcggactcgggcgtggcgctgccaggatactggat gctgtttgtgatgaatagcgcgggcgtcccgagcgtagcgagcacgatccgtgtg acccaggccgcagcttgataa 116 GOh2027 MGSSHHHHHHSSGLVPRGSHMGTASAPIGSAIPRNNWAVTCDSAQSGNECNKAID GNKDTFWHTFYGANGDPKPPHTYTIDMKTTQNVNGLSVLPRQDGNQNGWIGRHEV YLSSDGTNWGSPVASGSWFADSTTKYSNFETRPARYVRLVAVTEANGQPWTSIAE INVFQASSYTAPQPGLGRWGPTIDLPIVPAAAAIEPTSGRVLMWSSYRNDAAEGS PGGITLTSSWDPSTGIVSDRTVTVTKHDMFCPGISMDGNGQIVVTGGWDAKKTSL YDSSSDSWIPGPDMQVARGYQSSATMSDGRVFTIGGSFSGGVFEKNGEVYSPSSK TWTSLPNAKVNPMLTADKQGLWMSDNHAWLFGWKKGSVFQAGPSTAMNWYYTSGS GDVKSAGKRQSNRGVAPDAMCGNAVMYDAVKGKILTFGGSPDYTDSDATTNAHII TLGEPGTSPNTVFASNGLYFARTFHTSVVLPDGSTFITGGQRRGIPFEDSTPVFT PEIYVPEQDTFYKQNPNSIVRAYHSISLLLPDGRVFNGGGGLCGDCTTNHFDAQI FTPNYLYDSNGNLATRPKITRTSTQSVKVGGRITISTDSSITKASLIRYGTATHT VNTDQRRIPLTLTNNGGNSYSFQVPSDSGVALPGYWMLFVMNSAGVPSVASTIRV TQAAA 117 GOh2028 atgggcagcagccatcatcatcatcatcacagcagcggcctggtgccgcgcggca gccatatgggtaccgcctctgcccctatcggctcagccatcccgcgcaataactg ggccgtaacgtgcgacagcgcgcagagcggcaacgagtgcaataaagccatcgac ggcaataaagacaccttctggcacacgttttatggcgcaaatggcgacccgaagc caccgcatacctataccattgacatgaaaaccacccagaatgtgaacgggctgtc cgtgctgccgcgccaggacggcaatcagaacggatggatcggccgtcacgaggta tatttaagctccgacggcaccaactggggatccccggtcgcgtcgggcagctggt tcgccgacagcaccaccaagtattccaattttgaaacccgtcctgcacgctacgt gcgcttagtggccgtgacagaggcgaacggccagccatggacctcaatcgccgaa atcaatgtattccaagccagctcctataccgcgccgcagccaggacttgggcgtt ggggcccgaccatcgacctgcctatcgtacccgcagccgcggcgattgaaccaac gtcaggccgcgtactgatgtggagcagctaccgtaacgacgcggcggaaggcagc ccgggggcatcactctgacgtcgagttgggatccatccacgggcatcgtctccga ccgcaccgtgaccgtcacgaaacacgacatgttttgcccggggatcagcatggac ggcaacggccagatcgtcgtcacgggcggctgggacgccaagaagacgagcctct atgacagtagcagcgacagttggatcccggggccggacatgcaggtggcacgcgg gtaccagtccagcgcgaccatgtcagacggccgtgtctttacaatcggcggctca tttagtggcggagtgtttgagaagaatggcgaagtctatagcccctcatccaaaa cgtggacgtcacttccgaacgcgaaggtgaatcccatgttaaccgccgacaaaca gggcctgtacatgagcgacaaccatgcgtggctgttcggctggaagaaggggagc gtctttcaggcgggcccgtcgaccgcaatgaattggtattacacgtcaggaagcg gggacgtgaaatcagccggcaagcgccagtcgaaccgcggcgtggcgccggacgc aatgtgcggcaatgccgtgatgtatgacgcggtcaaaggcaagatcctgacattt ggcgggagtccggactacaccgacagtgacgcgacaaccaatgcccacattatta cccttggggagccggggacgagcccgaacacggtcttcgcgtccaatggcctcta tttcgcgcgtacctttcatacgtcggtggtcctgccggacggatcaacctttatc accggcggacagcgccgtggcatccccttcgaagactcgacccccgtctttacac cggagatttatgtgccggaacaggacacgttttataaacagaatccgaactcgat tgtacgcgcgtatcactccatcagccttcttctcccggacggacgtgtctttaat ggcggaggaggactgaaaggggactgcacgaccaatcattttgacgcgcagatct ttaccccgaattatctgtatgattcaaatgggaatctcgcgacccgtccgaaaat tacccgtacatcaacccagtccgtcaaagtgggcggccgcattacgatcagtacc gacagcagcattaccaaagcgtcactgattcgttacggcaccgcaacccatacag tcaacacggaccagcgccgtattccgttaaccctgaccaataacggtggcaattc gtatagcttccaggtaccgtcggactcgggcgtggcgctgccaggatactggatg ctgtttgtgatgaatagcgcgggcgtcccgagcgtagcgagcacgatccgtgtga cccaggccgcagcttgataa 118 GOh2028 MGSSHHHHHHSSGLVPRGSHMGTASAPIGSAIPRNNWAVTCDSAQSGNECNKAID GNKDTFWHTFYGANGDPKPPHTYTIDMKTTQNVNGLSVLPRQDGNQNGWIGRHEV YLSSDGTNWGSPVASGSWFADSTTKYSNFETRPARYVRLVAVTEANGQPWTSIAE INVFQASSYTAPQPGLGRWGPTIDLPIVPAAAAIEPTSGRVLMWSSYRNDAAEGS PGGITLTSSWDPSTGIVSDRTVTVTKHDMFCPGISMDGNGQIVVTGGWDAKKTSL YDSSSDSWIPGPDMQVARGYQSSATMSDGRVFTIGGSFSGGVFEKNGEVYSPSSK TWTSLPNAKVNPMLTADKQGLYMSDNHAWLFGWKKGSVFQAGPSTAMNWYYTSGS GDVKSAGKRQSNRGVAPDAMCGNAVMYDAVKGKILTFGGSPDYTDSDATTNAHII TLGEPGTSPNTVFASNGLYFARTFHTSVVLPDGSTFITGGQRRGIPFEDSTPVFT PEIYVPEQDTFYKQNPNSIVRAYHSISLLLPDGRVFNGGGGLKGDCTTNHFDAQI FTPNYLYDSNGNLATRPKITRTSTQSVKVGGRITISTDSSITKASLIRYGTATHT VNTDQRRIPLTLTNNGGNSYSFQVPSDSGVALPGYWMLFVMNSAGVPSVASTIRV TQAAA 119 GOh2029 atgggcagcagccatcatcatcatcatcacagcagcggcctggtgccgcgcggca gccatatgggtaccgcctctgcccctatcggctcagccatcccgcgcaataactg ggccgtaacgtgcgacagcgcgcagagcggcaacgagtgcaataaagccatcgac ggcaataaagacaccttctggcacacgttttatggcgcaaatggcgacccgaagc caccgcatacctataccattgacatgaaaaccacccagaatgtgaacgggctgtc cgtgctgccgcgccaggacggcaatcagaacggatggatcggccgtcacgaggta tatttaagctccgacggcaccaactggggatccccggtcgcgtcgggcagctggt tcgccgacagcaccaccaagtattccaattttgaaacccgtcctgcacgctacgt gcgcttagtggccgtgacagaggcgaacggccagccatggacctcaatcgccgaa atcaatgtattccaagccagctcctataccgcgccgcagccaggacttgggcgtt ggggcccgaccatcgacctgcctatcgtacccgcagccgcggcgattgaaccaac gtcaggccgcgtactgatgtggagcagctaccgtaacgacgcggcggaaggcagc ccgggcggcatcactctgacgtcgagttgggatccatccacgggcatcgtctccg accgcaccgtgaccgtcacgaaacacgacatgttttgcccggggatcagcatgga cggcaacggccagatcgtcgtcacgggcggctgggacgccaagaagacgagcctc tatgacagtagcagcgacagttggatcccggggccggacatgcaggtggcacgcg ggtaccagtccagcgcgaccatgtcagacggccgtgtctttacaatcggcggctc atttagtggcggagtgtttgagaagaatggcgaagtctatagcccctcatccaaa acgtggacgtcacttccgaacgcgaaggtgaatcccatgttaaccgccgacaaac agggcctgtacatgagcgacaaccatgcgtggctgttcggctggaagaaggggag cgtctttcaggcgggcccgtcgaccgcaatgaattggtattacacgtcaggaagc ggggacgtgaaatcagccggcaagcgccagtcgaaccgcggcgtggcgccggacg caatgtgcggcaatgccgtgatgtatgacgcggtcaaaggcaagatcctgacatt tggcgggagtccggactacaccgacagtgacgcgacaaccaatgcccacattatt acccttggggagccggggacgagcccgaacacggtcttcgcgtccaatggcctct atttcgcgcgtacctttcatacgtcggtggtcctgccggacggatcaacctttat caccggcggacagcgccgtggcatccccttcgaagactcgacccccgtctttaca ccggagatttatgtgccggaacaggacacgttttataaacagaatccgaactcga ttgtacgcgcgtatcactccatcagccttcttctcccggacggacgtgtctttaa tggcggaggaggactgcgtggggactgcacgaccaatcattttgacgcgcagatc tttaccccgaattatctgtatgattcaaatgggaatctcgcgacccgtccgaaaa ttacccgtacatcaacccagtccgtcaaagtgggcggccgcattacgatcagtac cgacagcagcattaccaaagcgtcactgattcgttacggcaccgcaacccataca gtcaacacggaccagcgccgtattccgttaaccctgaccaataacggtggcaatt cgtatagcttccaggtaccgtcggactcgggcgtggcgctgccaggatactggat gctgtttgtgatgaatagcgcgggcgtcccgagcgtagcgagcacgatccgtgtg acccaggccgcagcttgataa 120 GOh2029 MGSSHHHHHHSSGLVPRGSHMGTASAPIGSAIPRNNWAVTCDSAQSGNECNKAID GNKDTFWHTFYGANGDPKPPHTYTIDMKTTQNVNGLSVLPRQDGNQNGWIGRHEV YLSSDGTNWGSPVASGSWFADSTTKYSNFETRPARYVRLVAVTEANGQPWTSIAE INVFQASSYTAPQPGLGRWGPTIDLPIVPAAAAIEPTSGRVLMWSSYRNDAAEGS PGGITLTSSWDPSTGIVSDRTVTVTKHDMFCPGISMDGNGQIVVTGGWDAKKTSL YDSSSDSWIPGPDMQVARGYQSSATMSDGRVFTIGGSFSGGVFEKNGEVYSPSSK TWTSLPNAKVNPMLTADKQGLYMSDNHAWLFGWKKGSVFQAGPSTAMNWYYTSGS GDVKSAGKRQSNRGVAPDAMCGNAVMYDAVKGKILTFGGSPDYTDSDATTNAHII TLGEPGTSPNTVFASNGLYFARTFHTSVVLPDGSTFITGGQRRGIPFEDSTPVFT PEIYVPEQDTFYKQNPNSIVRAYHSISLLLPDGRVFNGGGGLRGDCTTNHFDAQI FTPNYLYDSNGNLATRPKITRTSTQSVKVGGRITISTDSSITKASLIRYGTATHT VNTDQRRIPLTLTNNGGNSYSFQVPSDSGVALPGYWMLFVMNSAGVPSVASTIRV TQAAA 121 GOh2030 atgggcagcagccatcatcatcatcatcacagcagcggcctggtgccgcgcggca gccatatgggtaccgcctctgcccctatcggctcagccatcccgcgcaataactg ggccgtaacgtgcgacagcgcgcagagcggcaacgagtgcaataaagccatcgac ggcaataaagacaccttctggcacacgttttatggcgcaaatggcgacccgaagc caccgcatacctataccattgacatgaaaaccacccagaatgtgaacgggctgtc cgtgctgccgcgccaggacggcaatcagaacggatggatcggccgtcacgaggta tatttaagctccgacggcaccaactggggatccccggtcgcgtcgggcagctggt tcgccgacagcaccaccaagtattccaattttgaaacccgtcctgcacgctacgt gcgcttagtggccgtgacagaggcgaacggccagccatggacctcaatcgccgaa atcaatgtattccaagccagctcctataccgcgccgcagccaggacttgggcgtt ggggcccgaccatcgacctgcctatcgtacccgcagccgcggcgattgaaccaac gtcaggccgcgtactgatgtggagcagctaccgtaacgacgcggcggaaggcagc ccgggcggcatcactctgacgtcgagttgggatccatccacgggcatcgtctccg accgcaccgtgaccgtcacgaaacacgacatggaatgcccggggatcagcatgga cggcaacggccagatcgtcgtcacgggcggctgggacgccaagaagacgagcctc tatgacagtagcagcgacagttggatcccggggccggacatgcaggtggcacgcg ggtaccagtccagcgcgaccatgtcagacggccgtgtctttacaatcggcggctc atttagtggcggagtgtttgagaagaatggcgaagtctatagcccctcatccaaa acgtggacgtcacttccgaacgcgaaggtgaatcccatgttaaccgccgacaaac agggcctgtacatgagcgacaaccatgcgtggctgttcggctggaagaaggggag cgtctttcaggcgggcccgtcgaccgcaatgaattggtattacacgtcaggaagc ggggacgtgaaatcagccggcaagcgccagtcgaaccgcggcgtggcgccggacg caatgtgcggcaatgccgtgatgtatgacgcggtcaaaggcaagatcctgacatt tggcgggagtccggactacaccgacagtgacgcgacaaccaatgcccacattatt acccttggggagccggggacgagcccgaacacggtcttcgcgtccaatggcctct atttcgcgcgtacctttcatacgtcggtggtcctgccggacggatcaacctttat caccggcggacagcgccgtggcatccccttcgaagactcgacccccgtctttaca ccggagatttatgtgccggaacaggacacgttttataaacagaatccgaactcga ttgtacgcgcgtatcactccatcagccttcttctcccggacggacgtgtctttaa tggcggaggaggactgtgcggggactgcacgaccaatcattttgacgcgcagatc tttaccccgaattatctgtatgattcaaatgggaatctcgcgacccgtccgaaaa ttacccgtacatcaacccagtccgtcaaagtgggggccgcattacgatcagtacc gacagcagcattaccaaagcgtcactgattcgttacggcaccgcaacccatacag tcaacacggaccagcgccgtattccgttaaccctgaccaataacggtggcaattc gtatagcttccaggtaccgtcggactcgggcgtggcgctgccaggatactggatg ctgtttgtgatgaatagcgcgggcgtcccgagcgtagcgagcacgatccgtgtga cccaggccgcagcttgataa 122 GOh2030 MGSSHHHHHHSSGLVPRGSHMGTASAPIGSAIPRNNWAVTCDSAQSGNECNKAID GNKDTFWHTFYGANGDPKPPHTYTIDMKTTQNVNGLSVLPRQDGNQNGWIGRHEV YLSSDGTNWGSPVASGSWFADSTTKYSNFETRPARYVRLVAVTEANGQPWTSIAE INVFQASSYTAPQPGLGRWGPTIDLPIVPAAAAIEPTSGRVLMWSSYRNDAAEGS PGGITLTSSWDPSTGIVSDRTVTVTKHDMECPGISMDGNGQIVVTGGWDAKKTSL YDSSSDSWIPGPDMQVARGYQSSATMSDGRVFTIGGSFSGGVFEKNGEVYSPSSK TWTSLPNAKVNPMLTADKQGLYMSDNHAWLFGWKKGSVFQAGPSTAMNWYYTSGS GDVKSAGKRQSNRGVAPDAMCGNAVMYDAVKGKILTFGGSPDYTDSDATTNAHII TLGEPGTSPNTVFASNGLYFARTFHTSVVLPDGSTFITGGQRRGIPFEDSTPVFT PEIYVPEQDTFYKQNPNSIVRAYHSISLLLPDGRVFNGGGGLCGDCTTNHFDAQI FTPNYLYDSNGNLATRPKITRTSTQSVKVGGRITISTDSSITKASLIRYGTATHT VNTDQRRIPLTLTNNGGNSYSFQVPSDSGVALPGYWMLFVMNSAGVPSVASTIRV TQAAA 123 GOh2031 atgggcagcagccatcatcatcatcatcacagcagcggcctggtgccgcgcggca gccatatgggtaccgcctctgcccctatcggctcagccatcccgcgcaataactg ggccgtaacgtgcgacagcgcgcagagcggcaacgagtgcaataaagccatcgac ggcaataaagacaccttctggcacacgttttatggcgcaaatggcgacccgaagc caccgcatacctataccattgacatgaaaaccacccagaatgtgaacgggctgtc cgtgctgccgcgccaggacggcaatcagaacggatggatcggccgtcacgaggta tatttaagctccgacggcaccaactggggatccccggtcgcgtcgggcagctggt tcgccgacagcaccaccaagtattccaattttgaaacccgtcctgcacgctacgt gcgcttagtggccgtgacagaggcgaacggccagccatggacctcaatcgccgaa atcaatgtattccaagccagctcctataccgcgccgcagccaggacttgggcgtt ggggcccgaccatcgacctgcctatcgtacccgcagccgcggcgattgaaccaac gtcaggccgcgtactgatgtggagcagctaccgtaacgacgcggcggaaggcagc ccgggcggcatcactctgacgtcgagttgggatccatccacgggcatcgtctccg accgcaccgtgaccgtcacgaaacacgacatgtattgcccggggatcagcatgga cggcaacggccagatcgtcgtcacgggcggctgggacgccaagaagacgagcctc tatgacagtagcagcgacagttggatcccggggccggacatgcaggtggcacgcg ggtaccagtccagcgcgaccatgtcagacggccgtgtctttacaatcggcggctc atttagtggcggagtgtttgagaagaatggcgaagtctatagcccctcatccaaa acgtggacgtcacttccgaacgcgaaggtgaatcccatgttaaccgccgacaaac agggcctgtacatgagcgacaaccatgcgtggctgttcggctggaagaaggggag cgtctttcaggcgggcccgtcgaccgcaatgaattggtattacacgtcaggaagc ggggacgtgaaatcagccggcaagcgccagtcgaaccgcggcgtggcgccggacg caatgtgcggcaatgccgtgatgtatgacgcggtcaaaggcaagatcctgacatt tggcgggagtccggactacaccgacagtgacgcgacaaccaatgcccacattatt acccttggggagccggggacgagcccgaacacggtcttcgcgtccaatggcctct atttcgcgcgtacctttcatacgtcggtggtcctgccggacggatcaacctttat caccggcggacagcgccgtggcatccccttcgaagactcgacccccgtctttaca ccggagatttatgtgccggaacaggacacgttttataaacagaatccgaactcga ttgtacgcgcgtatcactccatcagccttcttctcccggacggacgtgtctttaa tggcggaggaggactgtgcggggactgcacgaccaatcattttgacgcgcagatc tttaccccgaattatctgtatgattcaaatgggaatctcgcgacccgtccgaaaa ttacccgtacatcaacccagtccgtcaaagtgggcggccgcattacgatcagtac cgacagcagcattaccaaagcgtcactgattcgttacggcaccgcaacccataca gtcaacacggaccagcgccgtattccgttaaccctgaccaataacggtggcaatt cgtatagcttccaggtaccgtcggactcgggcgtggcgctgccaggatactggat gctgtttgtgatgaatagcgcgggcgtcccgagcgtagcgagcacgatccgtgtg acccaggccgcagcttgataa 124 GOh2031 MGSSHHHHHHSSGLVPRGSHMGTASAPIGSAIPRNNWAVTCDSAQSGNECNKAID GNKDTFWHTFYGANGDPKPPHTYTIDMKTTQNVNGLSVLPRQDGNQNGWIGRHEV YLSSDGTNWGSPVASGSWFADSTTKYSNFETRPARYVRLVAVTEANGQPWTSIAE INVFQASSYTAPQPGLGRWGPTIDLPIVPAAAAIEPTSGRVLMWSSYRNDAAEGS PGGITLTSSWDPSTGIVSDRTVTVTKHDMYCPGISMDGNGQIVVTGGWDAKKTSL YDSSSDSWIPGPDMQVARGYQSSATMSDGRVFTIGGSFSGGVFEKNGEVYSPSSK TWTSLPNAKVNPMLTADKQGLYMSDNHAWLFGWKKGSVFQAGPSTAMNWYYTSGS GDVKSAGKRQSNRGVAPDAMCGNAVMYDAVKGKILTFGGSPDYTDSDATTNAHII TLGEPGTSPNTVFASNGLYFARTFHTSVVLPDGSTFITGGQRRGIPFEDSTPVFT PEIYVPEQDTFYKQNPNSIVRAYHSISLLLPDGRVFNGGGGLCGDCTTNHFDAQI FTPNYLYDSNGNLATRPKITRTSTQSVKVGGRITISTDSSITKASLIRYGTATHT VNTDQRRIPLTLTNNGGNSYSFQVPSDSGVALPGYWMLFVMNSAGVPSVASTIRV TQAAA 125 GOh2032 atgggcagcagccatcatcatcatcatcacagcagcggcctggtgccgcgcggca gccatatgggtaccgcctctgcccctatcggctcagccatcccgcgcaataactg ggccgtaacgtgcgacagcgcgcagagcggcaacgagtgcaataaagccatcgac ggcaataaagacaccttctggcacacgttttatggcgcaaatggcgacccgaagc caccgcatacctataccattgacatgaaaaccacccagaatgtgaacgggctgtc cgtgctgccgcgccaggacggcaatcagaacggatggatcggccgtcacgaggta tatttaagctccgacggcaccaactggggatccccggtcgcgtcgggcagctggt tcgccgacagcaccaccaagtattccaattttgaaacccgtcctgcacgctacgt gcgcttagtggccgtgacagaggcgaacggccagccatggacctcaatcgccgaa atcaatgtattccaagccagctcctataccgcgccgcagccaggacttgggcgtt ggggcccgaccatcgacctgcctatcgtacccgcagccgcggcgattgaaccaac gtcaggccgcgtactgatgtggagcagctaccgtaacgacgcggcggaaggcagc ccgggcggcatcactctgacgtcgagttgggatccatccacgggcatcgtctccg accgcaccgtgaccgtcacgaaacacgacatgttttgcccggggatcagcatgga cggcaacggccagatcgtcgtcacgggcggctgggacgccaagaagacgagcctc tatgacagtagcagcgacagttggatcccggggccggacatgcaggtggcacgcg ggtaccagtccagcgcgaccatgtcagacggccgtgtctttacaatcggcggctc atttagtggcggagtgtttgagaagaatggcgaagtctatagcccctcatccaaa acgtggacgtcacttccgaacgcgaaggtgaatcccatgttaaccgccgacaaac agggcctgtacatgagcgacaagcatgcgtggctgttcggctggaagaaggggag cgtctttcaggcgggcccgtcgaccgcaatgaattggtattacacgtcaggaagc ggggacgtgaaatcagccggcaagcgccagtcgaaccgcggcgtggcgccggacg caatgtgcggcaatgccgtgatgtatgacgcggtcaaaggcaagatcctgacatt tggcgggagtccggactacaccgacagtgacgcgacaaccaatgcccacattatt acccttggggagccggggacgagcccgaacacggtcttcgcgtccaatggcctct atttcgcgcgtacctttcatacgtcggtggtcctgccggacggatcaacctttat caccggcggacagcgccgtggcatccccttcgaagactcgacccccgtctttaca ccggagatttatgtgccggaacaggacacgttttataaacagaatccgaactcga ttgtacgcgcgtatcactccatcagccttcttctcccggacggacgtgtctttaa tggcggaggaggactgtgcggggactgcacgaccaatcattttgacgcgcagatc tttaccccgaattatctgtatgattcaaatgggaatctcgcgacccgtccgaaaa ttacccgtacatcaacccagtccgtcaaagtgggcggccgcattacgatcagtac cgacagcagcattaccaaagcgtcactgattcgttacggcaccgcaacccataca gtcaacacggaccagcgccgtattccgttaaccctgaccaataacggtggcaatt cgtatagcttccaggtaccgtcggactcgggcgtggcgctgccaggatactggat gctgtttgtgatgaatagcgcgggcgtcccgagcgtagcgagcacgatccgtgtg acccaggccgcagcttgataa 126 GOh2032 MGSSHHHHHHSSGLVPRGSHMGTASAPIGSAIPRNNWAVTCDSAQSGNECNKAID GNKDTFWHTFYGANGDPKPPHTYTIDMKTTQNVNGLSVLPRQDGNQNGWIGRHEV YLSSDGTNWGSPVASGSWFADSTTKYSNFETRPARYVRLVAVTEANGQPWTSIAE INVFQASSYTAPQPGLGRWGPTIDLPIVPAAAAIEPTSGRVLMWSSYRNDAAEGS PGGITLTSSWDPSTGIVSDRTVTVTKHDMFCPGISMDGNGQIVVTGGWDAKKTSL YDSSSDSWIPGPDMQVARGYQSSATMSDGRVFTIGGSFSGGVFEKNGEVYSPSSK TWTSLPNAKVNPMLTADKQGLYMSDKHAWLFGWKKGSVFQAGPSTAMNWYYTSGS GDVKSAGKRQSNRGVAPDAMCGNAVMYDAVKGKILTFGGSPDYTDSDATTNAHII TLGEPGTSPNTVFASNGLYFARTFHTSVVLPDGSTFITGGQRRGIPFEDSTPVFT PEIYVPEQDTFYKQNPNSIVRAYHSISLLLPDGRVFNGGGGLCGDCTTNHFDAQI FTPNYLYDSNGNLATRPKITRTSTQSVKVGGRITISTDSSITKASLIRYGTATHT VNTDQRRIPLTLTNNGGNSYSFQVPSDSGVALPGYWMLFVMNSAGVPSVASTIRV TQAAA 127 GOh2033 atgggcagcagccatcatcatcatcatcacagcagcggcctggtgccgcgcggca gccatatgggtaccgcctctgcccctatcggctcagccatcccgcgcaataactg ggccgtaacgtgcgacagcgcgcagagcggcaacgagtgcaataaagccatcgac ggcaataaagacaccttctggcacacgttttatggcgcaaatggcgacccgaagc caccgcatacctataccattgacatgaaaaccacccagaatgtgaacgggctgtc cgtgctgccgcgccaggacggcaatcagaacggatggatcggccgtcacgaggta tatttaagctccgacggcaccaactggggatccccggtcgcgtcgggcagctggt tcgccgacagcaccaccaagtattccaattttgaaacccgtcctgcacgctacgt gcgcttagtggccgtgacagaggcgaacggccagccatggacctcaatcgccgaa atcaatgtattccaagccagctcctataccgcgccgcagccaggacttgggcgtt ggggcccgaccatcgacctgcctatcgtacccgcagccgcggcgattgaaccaac gtcaggccgcgtactgatgtggagcagctaccgtaacgacgcggcggaaggcagc ccgggcggcatcactctgacgtcgagttgggatccatccacgggcatcgtctccg accgcaccgtgaccgtcacgaaacacgacatgttttgcccggggatcagcatgga cggcaacggccagatcgtcgtcacgggcggctgggacgccaagaagacgagcctc tatgacagtagcagcgacagttggatcccggggccggacatgcaggtggcacgcg ggtaccagtccagcgcgaccatgtcagacggccgtgtctttacaatcggcggctc atttagtggcggagtgtttgagaagaatggcgaagtctatagcccctcatccaaa acgtggacgtcacttccgaacgcgaaggtgaatcccatgttaaccgccgacaaac agggcctgtacatgagcgaccgtcatgcgtggctgttcggctggaagaaggggag cgtctttcaggcgggcccgtcgaccgcaatgaattggtattacacgtcaggaagc ggggacgtgaaatcagccggcaagcgccagtcgaaccgcggcgtggcgccggacg caatgtgcggcaatgccgtgatgtatgacgcggtcaaaggcaagatcctgacatt tgggggagtccggactacaccgacagtgacgcgacaaccaatgcccacattatta cccttggggagccggggacgagcccgaacacggtcttcgcgtccaatggcctcta tttcgcgcgtacctttcatacgtcggtggtcctgccggacggatcaacctttatc accggcggacagcgccgtggcatccccttcgaagactcgacccccgtctttacac cggagatttatgtgccggaacaggacacgttttataaacagaatccgaactcgat tgtacgcgcgtatcactccatcagccttcttctcccggacggacgtgtctttaat ggcggaggaggactgtgcggggactgcacgaccaatcattttgacgcgcagatct ttaccccgaattatctgtatgattcaaatgggaatctcgcgacccgtccgaaaat tacccgtacatcaacccagtccgtcaaagtgggcggccgcattacgatcagtacc gacagcagcattaccaaagcgtcactgattcgttacggcaccgcaacccatacag tcaacacggaccagcgccgtattccgttaaccctgaccaataacggtggcaattc gtatagcttccaggtaccgtcggactcgggcgtggcgctgccaggatactggatg ctgtttgtgatgaatagcgcgggcgtcccgagcgtagcgagcacgatccgtgtga cccaggccgcagcttgataa 128 GOh2033 MGSSHHHHHHSSGLVPRGSHMGTASAPIGSAIPRNNWAVTCDSAQSGNECNKAID GNKDTFWHTFYGANGDPKPPHTYTIDMKTTQNVNGLSVLPRQDGNQNGWIGRHEV YLSSDGTNWGSPVASGSWFADSTTKYSNFETRPARYVRLVAVTEANGQPWTSIAE INVFQASSYTAPQPGLGRWGPTIDLPIVPAAAAIEPTSGRVLMWSSYRNDAAEGS PGGITLTSSWDPSTGIVSDRTVTVTKHDMFCPGISMDGNGQIVVTGGWDAKKTSL YDSSSDSWIPGPDMQVARGYQSSATMSDGRVFTIGGSFSGGVFEKNGEVYSPSSK TWTSLPNAKVNPMLTADKQGLYMSDRHAWLFGWKKGSVFQAGPSTAMNWYYTSGS GDVKSAGKRQSNRGVAPDAMCGNAVMYDAVKGKILTFGGSPDYTDSDATTNAHII TLGEPGTSPNTVFASNGLYFARTFHTSVVLPDGSTFITGGQRRGIPFEDSTPVFT PEIYVPEQDTFYKQNPNSIVRAYHSISLLLPDGRVFNGGGGLCGDCTTNHFDAQI FTPNYLYDSNGNLATRPKITRTSTQSVKVGGRITISTDSSITKASLIRYGTATHT VNTDQRRIPLTLTNNGGNSYSFQVPSDSGVALPGYWMLFVMNSAGVPSVASTIRV TQAAA 129 GOh2034 atgggcagcagccatcatcatcatcatcacagcagcggcctggtgccgcgcggca gccatatgggtaccgcctctgcccctatcggctcagccatcccgcgcaataactg ggccgtaacgtgcgacagcgcgcagagcggcaacgagtgcaataaagccatcgac ggcaataaagacaccttctggcacacgttttatggcgcaaatggcgacccgaagc caccgcatacctataccattgacatgaaaaccacccagaatgtgaacgggctgtc cgtgctgccgcgccaggacggcaatcagaacggatggatcggccgtcacgaggta tatttaagctccgacggcaccaactggggatccccggtcgcgtcgggcagctggt tcgccgacagcaccaccaagtattccaattttgaaacccgtcctgcacgctacgt gcgcttagtggccgtgacagaggcgaacggccagccatggacctcaatcgccgaa atcaatgtattccaagccagctcctataccgcgccgcagccaggacttgggcgtt ggggcccgaccatcgacctgcctatcgtacccgcagccgcggcgattgaaccaac gtcaggccgcgtactgatgtggagcagctaccgtaacgacgcggcggaaggcagc ccgggcggcatcactctgacgtcgagttgggatccatccacgggcatcgtctccg accgcaccgtgaccgtcacgaaacacgacatgttttgcccggggatcagcatgga cggcaacggccagatcgtcgtcacgggcggctgggacgccaagaagacgagcctc tatgacagtagcagcgacagttggatcccggggccggacatgcaggtggcacgcg ggtaccagtccagcgcgaccatgtcagacggccgtgtctttacaatcggcggctc atttagtggcggagtgtttgagaagaatggcgaagtctatagcccctcatccaaa acgtggacgtcacttccgaacgcgaaggtgaatcccatgttaaccgccgacaaac agggcctgtacatgagcgactggcatgcgtggctgttcggctggaagaaggggag cgtctttcaggcgggcccgtcgaccgcaatgaattggtattacacgtcaggaagc ggggacgtgaaatcagccggcaagcgccagtcgaaccgcggcgtggcgccggacg caatgtgcggcaatgccgtgatgtatgacgcggtcaaaggcaagatcctgacatt tggcgggagtccggactacaccgacagtgacgcgacaaccaatgcccacattatt acccttggggagccggggacgagcccgaacacggtcttcgcgtccaatggcctct atttcgcgcgtacctttcatacgtcggtggtcctgccggacggatcaacctttat caccggcggacagcgccgtggcatccccttcgaagactcgacccccgtctttaca ccggagatttatgtgccggaacaggacacgttttataaacagaatccgaactcga ttgtacgcgcgtatcactccatcagccttcttctcccggacggacgtgtctttaa tggcggaggaggactgtgcggggactgcacgaccaatcattttgacgcgcagatc tttaccccgaattatctgtatgattcaaatgggaatctcgcgacccgtccgaaaa ttacccgtacatcaacccagtccgtcaaagtgggcggccgcattacgatcagtac cgacagcagcattaccaaagcgtcactgattcgttacggcaccgcaacccataca gtcaacacggaccagcgccgtattccgttaaccctgaccaataacggtggcaatt cgtatagcttccaggtaccgtcggactcgggcgtggcgctgccaggatactggat gctgtttgtgatgaatagcgcgggcgtcccgagcgtagcgagcacgatccgtgtg acccaggccgcagcttgataa 130 GOh2034 MGSSHHHHHHSSGLVPRGSHMGTASAPIGSAIPRNNWAVTCDSAQSGNECNKAID GNKDTFWHTFYGANGDPKPPHTYTIDMKTTQNVNGLSVLPRQDGNQNGWIGRHEV YLSSDGTNWGSPVASGSWFADSTTKYSNFETRPARYVRLVAVTEANGQPWTSIAE INVFQASSYTAPQPGLGRWGPTIDLPIVPAAAAIEPTSGRVLMWSSYRNDAAEGS PGGITLTSSWDPSTGIVSDRTVTVTKHDMFCPGISMDGNGQIVVTGGWDAKKTSL YDSSSDSWIPGPDMQVARGYQSSATMSDGRVFTIGGSFSGGVFEKNGEVYSPSSK TWTSLPNAKVNPMLTADKQGLYMSDWHAWLFGWKKGSVFQAGPSTAMNWYYTSGS GDVKSAGKRQSNRGVAPDAMCGNAVMYDAVKGKILTFGGSPDYTDSDATTNAHII TLGEPGTSPNTVFASNGLYFARTFHTSVVLPDGSTFITGGQRRGIPFEDSTPVFT PEIYVPEQDTFYKQNPNSIVRAYHSISLLLPDGRVFNGGGGLCGDCTTNHFDAQI FTPNYLYDSNGNLATRPKITRTSTQSVKVGGRITISTDSSITKASLIRYGTATHT VNTDQRRIPLTLTNNGGNSYSFQVPSDSGVALPGYWMLFVMNSAGVPSVASTIRV TQAAA 131 GOh2037 atgggcagcagccatcatcatcatcatcacagcagcggcctggtgccgcgcggca gccatatgggtaccgcctctgcccctatcggctcagccatcccgcgcaataactg ggccgtaacgtgcgacagcgcgcagagcggcaacgagtgcaataaagccatcgac ggcaataaagacaccttctggcacacgttttatggcgcaaatggcgacccgaagc caccgcatacctataccattgacatgaaaaccacccagaatgtgaacgggctgtc cgtgctgccgcgccaggacggcaatcagaacggatggatcggccgtcacgaggta tatttaagctccgacggcaccaactggggatccccggtcgcgtcgggcagctggt tcgccgacagcaccaccaagtattccaattttgaaacccgtcctgcacgctacgt gcgcttagtggccgtgacagaggcgaacggccagccatggacctcaatcgccgaa atcaatgtattccaagccagctcctataccgcgccgcagccaggacttgggcgtt ggggcccgaccatcgacctgcctatcgtacccgcagccgcggcgattgaaccaac gtcaggccgcgtactgatgtggagcagctaccgtaacgacgcggcggaaggcagc ccgggcggcatcactctgacgtcgagttgggatccatccacgggcatcgtctccg accgcaccgtgaccgtcacgaaacacgacatgttttgcccggggatcagcatgga cggcaacggccagatcgtcgtcacgggcggctgggacgccaagaagacgagcctc tatgacagtagcagcgacagttggatcccggggccggacatgcaggtggcacgcg ggtaccagtccagcgcgaccatgtcagacggccgtgtctttacaatcggcggctc atttagtggcggagtgtttgagaagaatggcgaagtctatagcccctcatccaaa acgtggacgtcacttccgaacgcgaaggtgaatcccatgttaaccgccgacaaac agggcctgtacatgagcgacaaccatgcgtggctgttcggctggaagaaggggag cgtctttcaggcgggcccgtcgaccgcaatgaattggtattacacgtcaggaagc ggggacgtgaaatcagccggcaagcgccagtcgaaccgcggcgtggcgccggacg caatgtgcggcaatgccgtgatgtatgacgcggtcaaaggcaagatcctgacatt tggcgggagtccggactacaccgacagtgacgcgacaaccaatgcccacattatt acccttggggagccggggacgagcccgaacacggtcttcgcgtccaatggcctct atttcgcgcgtacctttcatacgtcggtggtcctgccggacggatcaacctttat caccggcggacagcgccgtggcatcccccgtgaagactcgacccccgtctttaca ccggagatttatgtgccggaacaggacacgttttataaacagaatccgaactcga ttgtacgcgcgtatcactccatcagccttcttctcccggacggacgtgtctttaa tggcggaggaggactgtgcggggactgcacgaccaatcattttgacgcgcagatc tttaccccgaattatctgtatgattcaaatgggaatctcgcgacccgtccgaaaa ttacccgtacatcaacccagtccgtcaaagtgggcggccgcattacgatcagtac cgacagcagcattaccaaagcgtcactgattcgttacggcaccgcaacccataca gtcaacacggaccagcgccgtattccgttaaccctgaccaataacggtggcaatt cgtatagcttccaggtaccgtcggactcgggcgtggcgctgccaggatactggat gctgtttgtgatgaatagcgcgggcgtcccgagcgtagcgagcacgatccgtgtg acccaggccgcagcttgataa 132 GOh2037 MGSSHHHHHHSSGLVPRGSHMGTASAPIGSAIPRNNWAVTCDSAQSGNECNKAID GNKDTFWHTFYGANGDPKPPHTYTIDMKTTQNVNGLSVLPRQDGNQNGWIGRHEV YLSSDGTNWGSPVASGSWFADSTTKYSNFETRPARYVRLVAVTEANGQPWTSIAE INVFQASSYTAPQPGLGRWGPTIDLPIVPAAAAIEPTSGRVLMWSSYRNDAAEGS PGGITLTSSWDPSTGIVSDRTVTVTKHDMFCPGISMDGNGQIVVTGGWDAKKTSL YDSSSDSWIPGPDMQVARGYQSSATMSDGRVFTIGGSFSGGVFEKNGEVYSPSSK TWTSLPNAKVNPMLTADKQGLYMSDNHAWLFGWKKGSVFQAGPSTAMNWYYTSGS GDVKSAGKRQSNRGVAPDAMCGNAVMYDAVKGKILTFGGSPDYTDSDATTNAHII TLGEPGTSPNTVFASNGLYFARTFHTSVVLPDGSTFITGGQRRGIPREDSTPVFT PEIYVPEQDTFYKQNPNSIVRAYHSISLLLPDGRVFNGGGGLCGDCTTNHFDAQI FTPNYLYDSNGNLATRPKITRTSTQSVKVGGRITISTDSSITKASLIRYGTATHT VNTDQRRIPLTLTNNGGNSYSFQVPSDSGVALPGYWMLFVMNSAGVPSVASTIRV TQAAA 133 GOh2038 atgggcagcagccatcatcatcatcatcacagcagcggcctggtgccgcgcggca gccatatgggtaccgcctctgcccctatcggctcagccatcccgcgcaataactg ggccgtaacgtgcgacagcgcgcagagcggcaacgagtgcaataaagccatcgac ggcaataaagacaccttctggcacacgttttatggcgcaaatggcgacccgaagc caccgcatacctataccattgacatgaaaaccacccagaatgtgaacgggctgtc cgtgctgccgcgccaggacggcaatcagaacggatggatcggccgtcacgaggta tatttaagctccgacggcaccaactggggatccccggtcgcgtcgggcagctggt tcgccgacagcaccaccaagtattccaattttgaaacccgtcctgcacgctacgt gcgcttagtggccgtgacagaggcgaacggccagccatggacctcaatcgccgaa atcaatgtattccaagccagctcctataccgcgccgcagccaggacttggggttg gggcccgaccatcgacctgcctatcgtacccgcagccgcggcgattgaaccaacg tcaggccgcgtactgatgtggagcagctaccgtaacgacgcggcggaaggcagcc cgggcggcatcactctgacgtcgagttgggatccatccacgggcatcgtctccga ccgcaccgtgaccgtcacgaaacacgacatgttttgcccggggatcagcatggac ggcaacggccagatcgtcgtcacgggcggctgggacgccaagaagacgagcctct atgacagtagcagcgacagttggatcccggggccggacatgcaggtggcacgcgg gtaccagtccagcgcgaccatgtcagacggccgtgtctttacaatcggcggctca tttagtggcggagtgtttgagaagaatggcgaagtctatagcccctcatccaaaa cgtggacgtcacttccgaacgcgaaggtgaatcccatgttaaccgccgacaaaca gggcctgtacatgagcgacaaccatgcgtggctgttcggctggaagaaggggagc gtctttcaggcgggcccgtcgaccgcaatgaattggtattacacgtcaggaagcg gggacgtgaaatcagccggcaagcgccagtcgaaccgcggcgtggcgccggacgc aatgtgcggcaatgccgtgatgtatgacgcggtcaaaggcaagatcctgacattt ggcgggagtccggactactgggacagtgacgcgacaaccaatgcccacattatta cccttggggagccggggacgagcccgaacacggtcttcgcgtccaatggcctcta tttcgcgcgtacctttcatacgtcggtggtcctgccggacggatcaacctttatc accggcggacagcgccgtggcatccccttcgaagactcgacccccgtctttacac cggagatttatgtgccggaacaggacacgttttataaacagaatccgaactcgat tgtacgcgcgtatcactccatcagccttcttctcccggacggacgtgtctttaat ggcggaggaggactgtgcggggactgcacgaccaatcattttgacgcgcagatct ttaccccgaattatctgtatgattcaaatgggaatctcgcgacccgtccgaaaat tacccgtacatcaacccagtccgtcaaagtgggcggccgcattacgatcagtacc gacagcagcattaccaaagcgtcactgattcgttacggcaccgcaacccatacag tcaacacggaccagcgccgtattccgttaaccctgaccaataacggtggcaattc gtatagcttccaggtaccgtcggactcgggcgtggcgctgccaggatactggatg ctgtttgtgatgaatagcgcgggcgtcccgagcgtagcgagcacgatccgtgtga cccaggccgcagcttgataa 134 GOh2038 MGSSHHHHHHSSGLVPRGSHMGTASAPIGSAIPRNNWAVTCDSAQSGNECNKAID GNKDTFWHTFYGANGDPKPPHTYTIDMKTTQNVNGLSVLPRQDGNQNGWIGRHEV YLSSDGTNWGSPVASGSWFADSTTKYSNFETRPARYVRLVAVTEANGQPWTSIAE INVFQASSYTAPQPGLGRWGPTIDLPIVPAAAAIEPTSGRVLMWSSYRNDAAEGS PGGITLTSSWDPSTGIVSDRTVTVTKHDMFCPGISMDGNGQIVVTGGWDAKKTSL YDSSSDSWIPSATMSDGRVFTIGGSFSGGVFEKNGEVYSPSSKTWTSLPNAKVNP MLTADKQGLYMSDNHAWLFGWKKGSVFQAGPSTAMNWYYTSGSGDVKSAGKRQSN RGVAPDAMCGNAVMYDAVKGKILTFGGSPDYWDSDATTNAHIITLGEPGTSPNTV FASNGLYFARTFHTSVVLPDGSTFITGGQRRGIPFEDSTPVFTPEIYVPEQDTFY KQNPNSIVRAYHSISLLLPDGRVFNGGGGLCGDCTTNHFDAQIFTPNYLYDSNGN LATRPKITRTSTQSVKVGGRITISTDSSITKASLIRYGTATHTVNTDQRRIPLTL TNNGGNSYSFQVPSDSGVALPGYWMLFVMNSAGVPSVASTIRVTQAAAGPDMQVA RGYQS 135 GOh2039 atgggcagcagccatcatcatcatcatcacagcagcggcctggtgccgcgcggca gccatatgggtaccgcctctgcccctatcggctcagccatcccgcgcaataactg ggccgtaacgtgcgacagcgcgcagagcggcaacgagtgcaataaagccatcgac ggcaataaagacaccttctggcacacgttttatggcgcaaatggcgacccgaagc caccgcatacctataccattgacatgaaaaccacccagaatgtgaacgggctgtc cgtgctgccgcgccaggacggcaatcagaacggatggatcggccgtcacgaggta tatttaagctccgacggcaccaactggggatccccggtcgcgtcgggcagctggt tcgccgacagcaccaccaagtattccaattttgaaacccgtcctgcacgctacgt gcgcttagtggccgtgacagaggcgaacggccagccatggacctcaatcgccgaa atcaatgtattccaagccagctcctataccgcgccgcagccaggacttgggcgtt ggggcccgaccatcgacctgcctatcgtacccgcagccgcggcgattgaaccaac gtcaggccgcgtactgatgtggagcagctaccgtaacgacgcggcgaaaggcagc ccgggcggcatcactctgacgtcgagttgggatccatccacgggcatcgtctccg accgcaccgtgaccgtcacgaaacacgacatgttttgcccggggatcagcatgga cggcaacggccagatcgtcgtcacgggcggctgggacgccaagaagacgagcctc tatgacagtagcagcgacagttggatcccggggccggacatgcaggtggcacgcg ggtaccagtccagcgcgaccatgtcagacggccgtgtctttacaatcggcggctc atttagtggcggagtgtttgagaagaatggcgaagtctatagcccctcatccaaa acgtggacgtcacttccgaacgcgaaggtgaatcccatgttaaccgccgacaaac agggcctgtacatgagcgacaaccatgcgtggctgttcggctggaagaaggggag cgtctttcaggcgggcccgtcgaccgcaatgaattggtattacacgtcaggaagc ggggacgtgaaatcagccggcaagcgccagtcgaaccgcggcgtggcgccggacg caatgtgcggcaatgccgtgatgtatgacgcggtcaaaggcaagatcctgacatt tggcgggagtccggactacaccgacagtgacgcgacaaccaatgcccacattatt acccttggggagccggggacgagcccgaacacggtcttcgcgtccaatggcctct atttcgcgcgtacctttcatacgtcggtggtcctgccggacggatcaacctttat caccggcggacagcgccgtggcatccccttcgaagactcgacccccgtctttaca ccggagatttatgtgccggaacaggacacgttttataaacagaatccgaactcga ttgtacgcgcgtatcactccatcagccttcttctcccggacggacgtgtctttaa tggcggaggaggactgtgcggggactgcacgaccaatcattttgacgcgcagatc tttaccccgaattatctgtatgattcaaatgggaatctcgcgacccgtccgaaaa ttacccgtacatcaacccagtccgtcaaagtgggcggccgcattacgatcagtac cgacagcagcattaccaaagcgtcactgattcgttacggcaccgcaacccataca gtcaacacggaccagcgccgtattccgttaaccctgaccaataacggtggcaatt cgtatagcttccaggtaccgtcggactcgggcgtggcgctgccaggatactggat gctgtttgtgatgaatagcgcgggcgtcccgagcgtagcgagcacgatccgtgtg acccaggccgcagcttgataa 136 GOh2039 MGSSHHHHHHSSGLVPRGSHMGTASAPIGSAIPRNNWAVTCDSAQSGNECNKAID GNKDTFWHTFYGANGDPKPPHTYTIDMKTTQNVNGLSVLPRQDGNQNGWIGRHEV YLSSDGTNWGSPVASGSWFADSTTKYSNFETRPARYVRLVAVTEANGQPWTSIAE INVFQASSYTAPQPGLGRWGPTIDLPIVPAAAAIEPTSGRVLMWSSYRNDAAKGS PGGITLTSSWDPSTGIVSDRTVTVTKHDMFCPGISMDGNGQIVVTGGWDAKKTSL YDSSSDSWIPGPDMQVARGYQSSATMSDGRVFTIGGSFSGGVFEKNGEVYSPSSK TWTSLPNAKVNPMLTADKQGLYMSDNHAWLFGWKKGSVFQAGPSTAMNWYYTSGS GDVKSAGKRQSNRGVAPDAMCGNAVMYDAVKGKILTFGGSPDYTDSDATTNAHII TLGEPGTSPNTVFASNGLYFARTFHTSVVLPDGSTFITGGQRRGIPFEDSTPVFT PEIYVPEQDTFYKQNPNSIVRAYHSISLLLPDGRVFNGGGGLCGDCTTNHFDAQI FTPNYLYDSNGNLATRPKITRTSTQSVKVGGRITISTDSSITKASLIRYGTATHT VNTDQRRIPLTLTNNGGNSYSFQVPSDSGVALPGYWMLFVMNSAGVPSVASTIRV TQAAA 137 GOh2041 atgggcagcagccatcatcatcatcatcacagcagcggcctggtgccgcgcggca gccatatgggtaccgcctctgcccctatcggctcagccatcccgcgcaataactg ggccgtaacgtgcgacagcgcgcagagcggcaacgagtgcaataaagccatcgac ggcaataaagacaccttctggcacacgttttatggcgcaaatggcgacccgaagc caccgcatacctataccattgacatgaaaaccacccagaatgtgaacgggctgtc cgtgctgccgcgccaggacggcaatcagaacggatggatcggccgtcacgaggta tatttaagctccgacggcaccaactggggatccccggtcgcgtcgggcagctggt tcgccgacagcaccaccaagtattccaattttgaaacccgtcctgcacgctacgt gcgcttagtggccgtgacagaggcgaacggccagccatggacctcaatcgccgaa atcaatgtattccaagccagctcctataccgcgccgcagccaggacttgggcgtt ggggcccgaccatcgacctgcctatcgtacccgcagccgcggcgattgaaccaac gtcaggccgcgtactgatgtggagcagctaccgtaacgacgcggcggaaggcagc ccgggcggcatcactctgacgtcgagttgggatccatccacgggcatcgtctccg accgcaccgtgaccgtcacgaaacacgacatgttttgcccggggatcagcatgga cggcaacggccagatcgtcgtcacgggcggctgggacgccaagaagacgagcctc tatgacagtagcagcgacagttggatcccggggccggacatgcaggtggcacgcg ggtaccagtccagcgcgaccatgtcagacggccgtgtctttacaatcggcggctc acgtagtggcggagtgtttgagaagaatggcgaagtctatagcccctcatccaaa acgtggacgtcacttccgaacgcgaaggtgaatcccatgttaaccgccgacaaac agggcctgtacatgagcgacaaccatgcgtggctgttcggctggaagaaggggag cgtctttcaggcgggcccgtcgaccgcaatgaattggtattacacgtcaggaagc ggggacgtgaaatcagccggcaagcgccagtcgaaccgcggcgtggcgccggacg caatgtgcggcaatgccgtgatgtatgacgcggtcaaaggcaagatcctgacatt tggcgggagtccggactacaccgacagtgacgcgacaaccaatgcccacattatt acccttggggagccggggacgagcccgaacacggtcttcgcgtccaatggcctct atttcgcgcgtacctttcatacgtcggtggtcctgccggacggatcaacctttat caccggcggacagcgccgtggcatccccttcgaagactcgacccccgtctttaca ccggagatttatgtgccggaacaggacacgttttataaacagaatccgaactcga ttgtacgcgcgtatcactccatcagccttcttctcccggacggacgtgtctttaa tggcggaggaggactgtgcggggactgcacgaccaatcattttgacgcgcagatc tttaccccgaattatctgtatgattcaaatgggaatctcgcgacccgtccgaaaa ttacccgtacatcaacccagtccgtcaaagtgggcggccgcattacgatcagtac cgacagcagcattaccaaagcgtcactgattcgttacggcaccgcaacccataca gtcaacacggaccagcgccgtattccgttaaccctgaccaataacggtggcaatt cgtatagcttccaggtaccgtcggactcgggcgtggcgctgccaggatactggat gctgtttgtgatgaatagcgcgggcgtcccgagcgtagcgagcacgatccgtgtg acccaggccgcagcttgataa 138 GOh2041 MGSSHHHHHHSSGLVPRGSHMGTASAPIGSAIPRNNWAVTCDSAQSGNECNKAID GNKDTFWHTFYGANGDPKPPHTYTIDMKTTQNVNGLSVLPRQDGNQNGWIGRHEV YLSSDGTNWGSPVASGSWFADSTTKYSNFETRPARYVRLVAVTEANGQPWTSIAE INVFQASSYTAPQPGLGRWGPTIDLPIVPAAAAIEPTSGRVLMWSSYRNDAAEGS PGGITLTSSWDPSTGIVSDRTVTVTKHDMFCPGISMDGNGQIVVTGGWDAKKTSL YDSSSDSWIPGPDMQVARGYQSSATMSDGRVFTIGGSRSGGVFEKNGEVYSPSSK TWTSLPNAKVNPMLTADKQGLYMSDNHAWLFGWKKGSVFQAGPSTAMNWYYTSGS GDVKSAGKRQSNRGVAPDAMCGNAVMYDAVKGKILTFGGSPDYTDSDATTNAHII TLGEPGTSPNTVFASNGLYFARTFHTSVVLPDGSTFITGGQRRGIPFEDSTPVFT PEIYVPEQDTFYKQNPNSIVRAYHSISLLLPDGRVFNGGGGLCGDCTTNHFDAQI FTPNYLYDSNGNLATRPKITRTSTQSVKVGGRITISTDSSITKASLIRYGTATHT VNTDQRRIPLTLTNNGGNSYSFQVPSDSGVALPGYWMLFVMNSAGVPSVASTIRV TQAAA 139 GOh2043 atgggcagcagccatcatcatcatcatcacagcagcggcctggtgccgcgcggca gccatatgggtaccgcctctgcccctatcggctcagccatcccgcgcaataactg ggccgtaacgtgcgacagcgcgcagagcggcaacgagtgcaataaagccatcgac ggcaataaagacaccttctggcacacgttttatggcgcaaatggcgacccgaagc caccgcatacctataccattgacatgaaaaccacccagaatgtgaacgggctgtc cgtgctgccgcgccaggacggcaatcagaacggatggatcggccgtcacgaggta tatttaagctccgacggcaccaactggggatccccggtcgcgtcgggcagctggt tcgccgacagcaccaccaagtattccaattttgaaacccgtcctgcacgctacgt gcgcttagtggccgtgacagaggcgaacggccagccatggacctcaatcgccgaa atcaatgtattccaagccagctcctataccgcgccgcagccaggacttgggcgtt ggggcccgaccatcgacctgcctatcgtacccgcagccgcggcgattgaaccaac gtcaggccgcgtactgatgtggagcagctaccgtaacgacgcggcggaaggcagc ccgggcggcatcactctgacgtcgagttgggatccatccacgggcatcgtctccg accgcaccgtgaccgtcacgaaacacgacatgttttgcccggggatcagcatgga cggcaacggccagatcgtcgtcacgggcggctgggacgccaagaagacgagcctc tatgacagtagcagcgacagttggtatccggggccggacatgcaggtggcacgcg ggtaccagtccagcgcgaccatgtcagacggccgtgtctttacaatcggcggctc atttagtggcggagtgtttgagaagaatggcgaagtctatagcccctcatccaaa acgtggacgtcacttccgaacgcgaaggtgaatcccatgttaaccgccgacaaac agggcctgtacatgagcgacaaccatgcgtggctgttcggctggaagaaggggag cgtctttcaggcgggcccgtcgaccgcaatgaattggtattacacgtcaggaagc ggggacgtgaaatcagccggcaagcgccagtcgaaccgcggcgtggcgccggacg caatgtgcggcaatgccgtgatgtatgacgcggtcaaaggcaagatcctgacatt tggcgggagtccggactacaccgacagtgacgcgacaaccaatgcccacattatt acccttggggagccggggacgagcccgaacacggtcttcgcgtccaatggcctct atttcgcgcgtacctttcatacgtcggtggtcctgccggacggatcaacctttat caccggcggacagcgccgtggcatccccttcgaagactcgacccccgtctttaca ccggagatttatgtgccggaacaggacacgttttataaacagaatccgaactcga ttgtacgcgcgtatcactccatcagccttcttctcccggacggacgtgtctttaa tggcggaggaggactgtgcggggactgcacgaccaatcattttgacgcgcagatc tttaccccgaattatctgtatgattcaaatgggaatctcgcgacccgtccgaaaa ttacccgtacatcaacccagtccgtcaaagtgggcggccgcattacgatcagtac cgacagcagcattaccaaagcgtcactgattcgttacggcaccgcaacccataca gtcaacacggaccagcgccgtattccgttaaccctgaccaataacggtggcaatt cgtatagcttccaggtaccgtcggactcgggcgtggcgctgccaggatactggat gctgtttgtgatgaatagcgcgggcgtcccgagcgtagcgagcacgatccgtgtg acccaggccgcagcttgataa 140 GOh2043 MGSSHHHHHHSSGLVPRGSHMGTASAPIGSAIPRNNWAVTCDSAQSGNECNKAID GNKDTFWHTFYGANGDPKPPHTYTIDMKTTQNVNGLSVLPRQDGNQNGWIGRHEV YLSSDGTNWGSPVASGSWFADSTTKYSNFETRPARYVRLVAVTEANGQPWTSIAE INVFQASSYTAPQPGLGRWGPTIDLPIVPAAAAIEPTSGRVLMWSSYRNDAAEGS PGGITLTSSWDPSTGIVSDRTVTVTKHDMFCPGISMDGNGQIVVTGGWDAKKTSL YDSSSDSWYPGPDMQVARGYQSSATMSDGRVFTIGGSFSGGVFEKNGEVYSPSSK TWTSLPNAKVNPMLTADKQGLYMSDNHAWLFGWKKGSVFQAGPSTAMNWYYTSGS GDVKSAGKRQSNRGVAPDAMCGNAVMYDAVKGKILTFGGSPDYTDSDATTNAHII TLGEPGTSPNTVFASNGLYFARTFHTSVVLPDGSTFITGGQRRGIPFEDSTPVFT PEIYVPEQDTFYKQNPNSIVRAYHSISLLLPDGRVFNGGGGLCGDCTTNHFDAQI FTPNYLYDSNGNLATRPKITRTSTQSVKVGGRITISTDSSITKASLIRYGTATHT VNTDQRRIPLTLTNNGGNSYSFQVPSDSGVALPGYWMLFVMNSAGVPSVASTIRV TQAAA 141 GOh2044 atgggcagcagccatcatcatcatcatcacagcagcggcctggtgccgcgcggca gccatatgggtacccattctgcccctatcggctcagccatcccgcgcaataactg ggccgtaacgtgcgacagcgcgcagagcggcaacgagtgcaataaagccatcgac ggcaataaagacaccttctggcacacgttttatggcgcaaatggcgacccgaagc caccgcatacctataccattgacatgaaaaccacccagaatgtgaacgggctgtc cgtgctgccgcgccaggacggcaatcagaacggatggatcggccgtcacgaggta tatttaagctccgacggcaccaactggggatccccggtcgcgtcgggcagctggt tcgccgacagcaccaccaagtattccaattttgaaacccgtcctgcacgctacgt gcgcttagtggccgtgacagaggcgaacggccagccatggacctcaatcgccgaa atcaatgtattccaagccagctcctataccgcgccgcagccaggacttgggcgtt ggggcccgaccatcgacctgcctatcgtacccgcagccgcggcgattgaaccaac gtcaggccgcgtactgatgtggagcagctaccgtaacgacgcggcggaaggcagc ccgggcggcatcactctgacgtcgagttgggatccatccacgggcatcgtctccg accgcaccgtgaccgtcacgaaacacgacatgttttgcccggggatcagcatgga cggcaacggccagatcgtcgtcacgggcggctgggacgccaagaagacgagcctc tatgacagtagcagcgacagttggatcccggggccggacatgcaggtggcacgcg ggtaccagtccagcgcgaccatgtcagacggccgtgtctttacaatcggcggctc atttagtggcggagtgtttgagaagaatggcgaagtctatagcccctcatccaaa acgtggacgtcacttccgaacgcgaaggtgaatcccatgttaaccgccgacaaac agggcctgtacatgagcgacaaccatgcgtggctgttcggctggaagaaggggag cgtctttcagggggcccgtcgaccgcaatgaattggtattacacgtcaggaagcg gggacgtgaaatcagccggcaagcgccagtcgaaccgcggcgtggcgccggacgc aatgtgcggcaatgccgtgatgtatgacgcggtcaaaggcaagatcctgacattt ggcgggagtccggactacaccgacagtgacgcgacaaccaatgcccacattatta cccttggggagccggggacgagcccgaacacggtcttcgcgtccaatggcctcta tttcgcgcgtacctttcatacgtcggtggtcctgccggacggatcaacctttatc accggcggacagcgccgtggcatccccttcgaagactcgacccccgtctttacac cggagatttatgtgccggaacaggacacgttttataaacagaatccgaactcgat tgtacgcgcgtatcactccatcagccttcttctcccggacggacgtgtctttaat ggcggaggaggactgtgcggggactgcacgaccaatcattttgacgcgcagatct ttaccccgaattatctgtatgattcaaatgggaatctcgcgacccgtccgaaaat tacccgtacatcaacccagtccgtcaaagtgggcggccgcattacgatcagtacc gacagcagcattaccaaagcgtcactgattcgttacggcaccgcaacccatacag tcaacacggaccagcgccgtattccgttaaccctgaccaataacggtggcaattc gtatagcttccaggtaccgtcggactcgggcgtggcgctgccaggatactggatg ctgtttgtgatgaatagcgcgggcgtcccgagcgtagcgagcacgatccgtgtga cccaggccgcagcttgataa 142 GOh2044 MGSSHHHHHHSSGLVPRGSHMGTHSAPIGSAIPRNNWAVTCDSAQSGNECNKAID GNKDTFWHTFYGANGDPKPPHTYTIDMKTTQNVNGLSVLPRQDGNQNGWIGRHEV YLSSDGTNWGSPVASGSWFADSTTKYSNFETRPARYVRLVAVTEANGQPWTSIAE INVFQASSYTAPQPGLGRWGPTIDLPIVPAAAAIEPTSGRVLMWSSYRNDAAEGS PGGITLTSSWDPSTGIVSDRTVTVTKHDMFCPGISMDGNGQIVVTGGWDAKKTSL YDSSSDSWIPGPDMQVARGYQSSATMSDGRVFTIGGSFSGGVFEKNGEVYSPSSK TWTSLPNAKVNPMLTADKQGLYMSDNHAWLFGWKKGSVFQAGPSTAMNWYYTSGS GDVKSAGKRQSNRGVAPDAMCGNAVMYDAVKGKILTFGGSPDYTDSDATTNAHII TLGEPGTSPNTVFASNGLYFARTFHTSVVLPDGSTFITGGQRRGIPFEDSTPVFT PEIYVPEQDTFYKQNPNSIVRAYHSISLLLPDGRVFNGGGGLCGDCTTNHFDAQI FTPNYLYDSNGNLATRPKITRTSTQSVKVGGRITISTDSSITKASLIRYGTATHT VNTDQRRIPLTLTNNGGNSYSFQVPSDSGVALPGYWMLFVMNSAGVPSVASTIRV TQAAA 143 GOh2045 atgggcagcagccatcatcatcatcatcacagcagcggcctggtgccgcgcggca gccatatgggtaccgcctctgcccctcgtggctcagccatcccgcgcaataactg ggccgtaacgtgcgacagcgcgcagagcggcaacgagtgcaataaagccatcgac ggcaataaagacaccttctggcacacgttttatggcgcaaatggcgacccgaagc caccgcatacctataccattgacatgaaaaccacccagaatgtgaacgggctgtc cgtgctgccgcgccaggacggcaatcagaacggatggatcggccgtcacgaggta tatttaagctccgacggcaccaactggggatccccggtcgcgtcgggcagctggt tcgccgacagcaccaccaagtattccaattttgaaacccgtcctgcacgctacgt gcgcttagtggccgtgacagaggcgaacggccagccatggacctcaatcgccgaa atcaatgtattccaagccagctcctataccgcgccgcagccaggacttgggcgtt ggggcccgaccatcgacctgcctatcgtacccgcagccgcggcgattgaaccaac gtcaggccgcgtactgatgtggagcagctaccgtaacgacgcggcggaaggcagc ccgggcggcatcactctgacgtcgagttgggatccatccacgggcatcgtctccg accgcaccgtgaccgtcacgaaacacgacatgttttgcccggggatcagcatgga cggcaacggccagatcgtcgtcacgggcggctgggacgccaagaagacgagcctc tatgacagtagcagcgacagttggatcccggggccggacatgcaggtggcacgcg ggtaccagtccagcgcgaccatgtcagacggccgtgtctttacaatcggcggctc atttagtggcggagtgtttgagaagaatggcgaagtctatagcccctcatccaaa acgtggacgtcacttccgaacgcgaaggtgaatcccatgttaaccgccgacaaac agggcctgtacatgagcgacaaccatgcgtggctgttcggctggaagaaggggag cgtctttcagggggcccgtcgaccgcaatgaattggtattacacgtcaggaagcg gggacgtgaaatcagccggcaagcgccagtcgaaccgcggcgtggcgccggacgc aatgtgcggcaatgccgtgatgtatgacgcggtcaaaggcaagatcctgacattt ggcgggagtccggactacaccgacagtgacgcgacaaccaatgcccacattatta cccttggggagccggggacgagcccgaacacggtcttcgcgtccaatggcctcta tttcgcgcgtacctttcatacgtcggtggtcctgccggacggatcaacctttatc accggcggacagcgccgtggcatccccttcgaagactcgacccccgtctttacac cggagatttatgtgccggaacaggacacgttttataaacagaatccgaactcgat tgtacgcgcgtatcactccatcagccttcttctcccggacggacgtgtctttaat ggcggaggaggactgtgcggggactgcacgaccaatcattttgacgcgcagatct ttaccccgaattatctgtatgattcaaatgggaatctcgcgacccgtccgaaaat tacccgtacatcaacccagtccgtcaaagtgggcggccgcattacgatcagtacc gacagcagcattaccaaagcgtcactgattcgttacggcaccgcaacccatacag tcaacacggaccagcgccgtattccgttaaccctgaccaataacggtggcaattc gtatagcttccaggtaccgtcggactcgggcgtggcgctgccaggatactggatg ctgtttgtgatgaatagcgcgggcgtcccgagcgtagcgagcacgatccgtgtga cccaggccgcagcttgataa 144 GOh2045 MGSSHHHHHHSSGLVPRGSHMGTASAPRGSAIPRNNWAVTCDSAQSGNECNKAID GNKDTFWHTFYGANGDPKPPHTYTIDMKTTQNVNGLSVLPRQDGNQNGWIGRHEV YLSSDGTNWGSPVASGSWFADSTTKYSNFETRPARYVRLVAVTEANGQPWTSIAE INVFQASSYTAPQPGLGRWGPTIDLPIVPAAAAIEPTSGRVLMWSSYRNDAAEGS PGGITLTSSWDPSTGIVSDRTVTVTKHDMFCPGISMDGNGQIVVTGGWDAKKTSL YDSSSDSWIPGPDMQVARGYQSSATMSDGRVFTIGGSFSGGVFEKNGEVYSPSSK TWTSLPNAKVNPMLTADKQGLYMSDNHAWLFGWKKGSVFQAGPSTAMNWYYTSGS GDVKSAGKRQSNRGVAPDAMCGNAVMYDAVKGKILTFGGSPDYTDSDATTNAHII TLGEPGTSPNTVFASNGLYFARTFHTSVVLPDGSTFITGGQRRGIPFEDSTPVFT PEIYVPEQDTFYKQNPNSIVRAYHSISLLLPDGRVFNGGGGLCGDCTTNHFDAQI FTPNYLYDSNGNLATRPKITRTSTQSVKVGGRITISTDSSITKASLIRYGTATHT VNTDQRRIPLTLTNNGGNSYSFQVPSDSGVALPGYWMLFVMNSAGVPSVASTIRV TQAAA 145 GOh2046 atgggcagcagccatcatcatcatcatcacagcagcggcctggtgccgcgcggca gccatatgggtaccgcctctgcccctatgggctcagccatcccgcgcaataactg ggccgtaacgtgcgacagcgcgcagagcggcaacgagtgcaataaagccatcgac ggcaataaagacaccttctggcacacgttttatggcgcaaatggcgacccgaagc caccgcatacctataccattgacatgaaaaccacccagaatgtgaacgggctgtc cgtgctgccgcgccaggacggcaatcagaacggatggatcggccgtcacgaggta tatttaagctccgacggcaccaactggggatccccggtcgcgtcgggcagctggt tcgccgacagcaccaccaagtattccaattttgaaacccgtcctgcacgctacgt gcgcttagtggccgtgacagaggcgaacggccagccatggacctcaatcgccgaa atcaatgtattccaagccagctcctataccgcgccgcagccaggacttgggcgtt ggggcccgaccatcgacctgcctatcgtacccgcagccgcggcgattgaaccaac gtcaggccgcgtactgatgtggagcagctaccgtaacgacgcggcggaaggcagc ccgggcggcatcactctgacgtcgagttgggatccatccacgggcatcgtctccg accgcaccgtgaccgtcacgaaacacgacatgttttgcccggggatcagcatgga cggcaacggccagatcgtcgtcacgggcggctgggacgccaagaagacgagcctc tatgacagtagcagcgacagttggatcccggggccggacatgcaggtggcacgcg ggtaccagtccagcgcgaccatgtcagacggccgtgtctttacaatcggcggctc atttagtggcggagtgtttgagaagaatggcgaagtctatagcccctcatccaaa acgtggacgtcacttccgaacgcgaaggtgaatcccatgttaaccgccgacaaac agggcctgtacatgagcgacaaccatgcgtggctgttcggctggaagaaggggag cgtctttcaggcgggcccgtcgaccgcaatgaattggtattacacgtcaggaagc ggggacgtgaaatcagccggcaagcgccagtcgaaccgcggcgtggcgccggacg caatgtgcggcaatgccgtgatgtatgacgcggtcaaaggcaagatcctgacatt tgggggagtccggactacaccgacagtgacgcgacaaccaatgcccacattatta cccttggggagccggggacgagcccgaacacggtcttcgcgtccaatggcctcta tttcgcgcgtacctttcatacgtcggtggtcctgccggacggatcaacctttatc accggcggacagcgccgtggcatccccttcgaagactcgacccccgtctttacac cggagatttatgtgccggaacaggacacgttttataaacagaatccgaactcgat tgtacgcgcgtatcactccatcagccttcttctcccggacggacgtgtctttaat ggcggaggaggactgtgcggggactgcacgaccaatcattttgacgcgcagatct ttaccccgaattatctgtatgattcaaatgggaatctcgcgacccgtccgaaaat tacccgtacatcaacccagtccgtcaaagtgggcggccgcattacgatcagtacc gacagcagcattaccaaagcgtcactgattcgttacggcaccgcaacccatacag tcaacacggaccagcgccgtattccgttaaccctgaccaataacggtggcaattc gtatagcttccaggtaccgtcggactcgggcgtggcgctgccaggatactggatg ctgtttgtgatgaatagcgcgggcgtcccgagcgtagcgagcacgatccgtgtga cccaggccgcagcttgataa 146 GOh2046 MGSSHHHHHHSSGLVPRGSHMGTASAPMGSAIPRNNWAVTCDSAQSGNECNKAID GNKDTFWHTFYGANGDPKPPHTYTIDMKTTQNVNGLSVLPRQDGNQNGWIGRHEV YLSSDGTNWGSPVASGSWFADSTTKYSNFETRPARYVRLVAVTEANGQPWTSIAE INVFQASSYTAPQPGLGRWGPTIDLPIVPAAAAIEPTSGRVLMWSSYRNDAAEGS PGGITLTSSWDPSTGIVSDRTVTVTKHDMFCPGISMDGNGQIVVTGGWDAKKTSL YDSSSDSWIPGPDMQVARGYQSSATMSDGRVFTIGGSFSGGVFEKNGEVYSPSSK TWTSLPNAKVNPMLTADKQGLYMSDNHAWLFGWKKGSVFQAGPSTAMNWYYTSGS GDVKSAGKRQSNRGVAPDAMCGNAVMYDAVKGKILTFGGSPDYTDSDATTNAHII TLGEPGTSPNTVFASNGLYFARTFHTSVVLPDGSTFITGGQRRGIPFEDSTPVFT PEIYVPEQDTFYKQNPNSIVRAYHSISLLLPDGRVFNGGGGLCGDCTTNHFDAQI FTPNYLYDSNGNLATRPKITRTSTQSVKVGGRITISTDSSITKASLIRYGTATHT VNTDQRRIPLTLTNNGGNSYSFQVPSDSGVALPGYWMLFVMNSAGVPSVASTIRV TQAAA 147 GOh2047 atgggcagcagccatcatcatcatcatcacagcagcggcctggtgccgcgcggca gccatatgggtaccgcctctgcccctatcggctcagccatcccgcgcaataactg ggccgtaacgtgcgacagcgcgcagagcggcaacgagtgcaataaagccatcgac ggcaataaagacaccttctggcacacgttttatggcgcaaatggcgacccgaagc caccgcatacctataccattgacatgaaaaccacccagaatgtgaacgggctgtc cgtgctgccgcgccaggacggcaatcagaacggatggatcggccgtcacgaggta tatttaagctccgacggcaccaactggggatccccggtcgcgtcgggcagctggt tcgccgacagcaccaccaagtattccaattttgaaacccgtcctgcacgctacgt gcgcttagtggccgtgacagaggcgaacggccagccatggacctcaatcgccgaa atcaatgtattccaagccagctcctataccgcgccgcagccaggacttgggcgtt ggggcccgaccatcgacctgcctatcgtacccgcagccgcggcgattgaaccaac gtcaggccgcgtactgatgtggagcagctaccgtaacgacgcggcggaaggcagc ccgggcggcatcactctgacgtcgagttgggatccatccacgggcatcgtctccg accgcaccgtgaccgtcacgaaacacgacatgttttgcccggggatcagcatgga cggcaacggccagatcgtcgtcacgggcggctgggacgccaagaagacgagcctc tatgacagtagcagcgacagttggatcccggggccggacatgcaggtggcacgcg ggtaccagtccagcgcgaccatgtcagacggccgtgtctttacaatcggcggctc atttagtggcggagtgtttgagaagaatggcgaagtctatagcccctcatccaaa acgtggacgtcacttccgaacgcgaaggtgaatcccatgttaaccgccgacaaac agggcctgtacatgagcgacaaccatgcgtggctgttcggctggaagaaggggag cgtctttcaggcgggcccgtcgaccgcaatgaattggtattacacgtcaggaagc ggggacgtgaaatcagccggcaagcgccagtcgaaccgcggcgtggcgccggacg caatgtgcggcaatgccgtgatgtatgacgcggtcaaaggcaagatcctgacatt tggcgggagtccggactacaccgacagtgacgcgacaaccaatgcccacattatt acccttggggagccggggacgagcccgaacacggtcttcgcgtccaatggcctct atttcgcgcgtacctttcatacgtcggtggtcctgccggacggatcaacctttat caccggcggacagcgccgtggcatccccttcgaagactcgacccccgtctttaca ccggagatttatgtgccggaacaggacacgttttataaacagaatccgaactcga ttgtacgcgcgtatcactccatcagccttcttctcccggacggacgtgtctttaa tggcggaggaggactgtgcggggactgcacgaccaatcattttgacgcgcagatc tttaccccgaattatctgtatgattcaaatgggaatctcgcgacccgtccgaaaa ttacccgtacatcaacccaggatgtcaaagtgggcggccgcattacgatcagtac cgacagcagcattaccaaagcgtcactgattcgttacggcaccgcaacccataca gtcaacacggaccagcgccgtattccgttaaccctgaccaataacggtggcaatt cgtatagcttccaggtaccgtcggactcgggcgtggcgctgccaggatactggat gctgtttgtgatgaatagcgcgggcgtcccgagcgtagcgagcacgatccgtgtg acccaggccgcagcttgataa 148 GOh2047 MGSSHHHHHHSSGLVPRGSHMGTASAPIGSAIPRNNWAVTCDSAQSGNECNKAID GNKDTFWHTFYGANGDPKPPHTYTIDMKTTQNVNGLSVLPRQDGNQNGWIGRHEV YLSSDGTNWGSPVASGSWFADSTTKYSNFETRPARYVRLVAVTEANGQPWTSIAE INVFQASSYTAPQPGLGRWGPTIDLPIVPAAAAIEPTSGRVLMWSSYRNDAAEGS PGGITLTSSWDPSTGIVSDRTVTVTKHDMFCPGISMDGNGQIVVTGGWDAKKTSL YDSSSDSWIPGPDMQVARGYQSSATMSDGRVFTIGGSFSGGVFEKNGEVYSPSSK TWTSLPNAKVNPMLTADKQGLYMSDNHAWLFGWKKGSVFQAGPSTAMNWYYTSGS GDVKSAGKRQSNRGVAPDAMCGNAVMYDAVKGKILTFGGSPDYTDSDATTNAHII TLGEPGTSPNTVFASNGLYFARTFHTSVVLPDGSTFITGGQRRGIPFEDSTPVFT PEIYVPEQDTFYKQNPNSIVRAYHSISLLLPDGRVFNGGGGLCGDCTTNHFDAQI FTPNYLYDSNGNLATRPKITRTSTQDVKVGGRITISTDSSITKASLIRYGTATHT VNTDQRRIPLTLTNNGGNSYSFQVPSDSGVALPGYWMLFVMNSAGVPSVASTIRV TQAAA 149 GOh2048 atgggcagcagccatcatcatcatcatcacagcagcggcctggtgccgcgcggca gccatatgggtaccgcctctgcccctatcggctcagccatcccgcgcaataactg ggccgtaacgtgcgacagcgcgcagagcggcaacgagtgcaataaagccatcgac ggcaataaagacaccttctggcacacgttttatggcgcaaatggcgacccgaagc caccgcatacctataccattgacatgaaaaccacccagaatgtgaacgggctgtc cgtgctgccgcgccaggacggcaatcagaacggatggatcggccgtcacgaggta tatttaagctccgacggcaccaactggggatccccggtcgcgtcgggcagctggt tcgccgacagcaccaccaagtattccaattttgaaacccgtcctgcacgctacgt gcgcttagtggccgtgacagaggcgaacggccagccatggacctcaatcgccgaa atcaatgtattccaagccagctcctataccgcgccgcagccaggacttgggcgtt ggggcccgaccatcgacctgcctatcgtacccgcagccgcggcgattgaaccaac gtcaggccgcgtactgatgtggagcagctaccgtaacgacgcggcggaaggcagc ccgggcggcatcactctgacgtcgagttgggatccatccacgggcatcgtctccg accgcaccgtgaccgtcacgaaacacgacatgttttgcccggggatcagcatgga cggcaacggccagatcgtcgtcacgggcggctgggacgccaagaagacgagcctc tatgacagtagcagcgacagttggagcccggggccggacatgcaggtggcacgcg ggtaccagtccagcgcgaccatgtcagacggccgtgtctttacaatcggcggctc atttagtggcggagtgtttgagaagaatggcgaagtctatagcccctcatccaaa acgtggacgtcacttccgaacgcgaaggtgaatcccatgttaaccgccgacaaac agggcctgtacatgagcgacaaccatgcgtggctgttcggctggaagaaggggag cgtctttcaggcgggcccgtcgaccgcaatgaattggtattacacgtcaggaagc ggggacgtgaaatcagccggcaagcgccagtcgaaccgcggcgtggcgccggacg caatgtgcggcaatgccgtgatgtatgacgcggtcaaaggcaagatcctgacatt tggcgggagtccggactacaccgacagtgacgcgacaaccaatgcccacattatt acccttggggagccggggacgagcccgaacacggtcttcgcgtccaatggcctct atttcgcgcgtacctttcatacgtcggtggtcctgccggacggatcaacctttat caccggcggacagcgccgtggcatccccttcgaagactcgacccccgtctttaca ccggagatttatgtgccggaacaggacacgttttataaacagaatccgaactcga ttgtacgcgcgtatcactccatcagccttcttctcccggacggacgtgtctttaa tggcggaggaggactgtgcggggactgcacgaccaatcattttgacgcgcagatc tttaccccgaattatctgtatgattcaaatgggaatctcgcgacccgtccgaaaa ttacccgtacatcaacccagtccgtcaaagtgggcggccgcattacgatcagtac cgacagcagcattaccaaagcgtcactgattcgttacggcaccgcaacccataca gtcaacacggaccagcgccgtattccgttaaccctgaccaataacggtggcaatt cgtatagcttccaggtaccgtcggactcgggcgtggcgctgccaggatactggat gctgtttgtgatgaatagcgcgggcgtcccgagcgtagcgagcacgatccgtgtg acccaggccgcagcttgataa 150 GOh2048 MGSSHHHHHHSSGLVPRGSHMGTASAPIGSAIPRNNWAVTCDSAQSGNECNKAID GNKDTFWHTFYGANGDPKPPHTYTIDMKTTQNVNGLSVLPRQDGNQNGWIGRHEV YLSSDGTNWGSPVASGSWFADSTTKYSNFETRPARYVRLVAVTEANGQPWTSIAE INVFQASSYTAPQPGLGRWGPTIDLPIVPAAAAIEPTSGRVLMWSSYRNDAAEGS PGGITLTSSWDPSTGIVSDRTVTVTKHDMFCPGISMDGNGQIVVTGGWDAKKTSL YDSSSDSWSPGPDMQVARGYQSSATMSDGRVFTIGGSFSGGVFEKNGEVYSPSSK TWTSLPNAKVNPMLTADKQGLYMSDNHAWLFGWKKGSVFQAGPSTAMNWYYTSGS GDVKSAGKRQSNRGVAPDAMCGNAVMYDAVKGKILTFGGSPDYTDSDATTNAHII TLGEPGTSPNTVFASNGLYFARTFHTSVVLPDGSTFITGGQRRGIPFEDSTPVFT PEIYVPEQDTFYKQNPNSIVRAYHSISLLLPDGRVFNGGGGLCGDCTTNHFDAQI FTPNYLYDSNGNLATRPKITRTSTQSVKVGGRITISTDSSITKASLIRYGTATHT VNTDQRRIPLTLTNNGGNSYSFQVPSDSGVALPGYWMLFVMNSAGVPSVASTIRV TQAAA 151 GOh2050 atgggcagcagccatcatcatcatcatcacagcagcggcctggtgccgcgcggca gccatatgggtaccgcctctgcccctatcggctcagccatcccgcgcaataactg ggccgtaacgtgcgacagcgcgcagagcggcaacgagtgcaataaagccatcgac ggcaataaagacaccttctggcacacgccgtatggcgcaaatggcgacccgaagc caccgcatacctataccattgacatgaaaaccacccagaatgtgaacgggctgtc cgtgctgccgcgccaggacggcaatcagaacggatggatcggccgtcacgaggta tatttaagctccgacggcaccaactggggatccccggtcgcgtcgggcagctggt tcgccgacagcaccaccaagtattccaattttgaaacccgtcctgcacgctacgt gcgcttagtggccgtgacagaggcgaacggccagccatggacctcaatcgccgaa atcaatgtattccaagccagctcctataccgcgccgcagccaggacttgggcgtt ggggcccgaccatcgacctgcctatcgtacccgcagccgcggcgattgaaccaac gtcaggccgcgtactgatgtggagcagctaccgtaacgacgcggcggaaggcagc ccgggcggcatcactctgacgtcgagttgggatccatccacgggcatcgtctccg accgcaccgtgaccgtcacgaaacacgacatgttttgcccggggatcagcatgga cggcaacggccagatcgtcgtcacgggcggctgggacgccaagaagacgagcctc tatgacagtagcagcgacagttggatcccggggccggacatgcaggtggcacgcg ggtaccagtccagcgcgaccatgtcagacggccgtgtctttacaatcggcggctc atttagtggcggagtgtttgagaagaatggcgaagtctatagcccctcatccaaa acgtggacgtcacttccgaacgcgaaggtgaatcccatgttaaccgccgacaaac agggcctgtacatgagcgacaaccatgcgtggctgttcggctggaagaaggggag cgtctttcagggggcccgtcgaccgcaatgaattggtattacacgtcaggaagcg gggacgtgaaatcagccggcaagcgccagtcgaaccgcggcgtggcgccggacgc aatgtgcggcaatgccgtgatgtatgacgcggtcaaaggcaagatcctgacattt ggcgggagtccggactacaccgacagtgacgcgacaaccaatgcccacattatta cccttggggagccggggacgagcccgaacacggtcttcgcgtccaatggcctcta tttcgcgcgtacctttcatacgtcggtggtcctgccggacggatcaacctttatc accggcggacagcgccgtggcatccccttcgaagactcgacccccgtctttacac cggagatttatgtgccggaacaggacacgttttataaacagaatccgaactcgat tgtacgcgcgtatcactccatcagccttcttctcccggacggacgtgtctttaat ggcggaggaggactgtgcggggactgcacgaccaatcattttgacgcgcagatct ttaccccgaattatctgtatgattcaaatgggaatctcgcgacccgtccgaaaat tacccgtacatcaacccagtccgtcaaagtgggcggccgcattacgatcagtacc gacagcagcattaccaaagcgtcactgattcgttacggcaccgcaacccatacag tcaacacggaccagcgccgtattccgttaaccctgaccaataacggtggcaattc gtatagcttccaggtaccgtcggactcgggcgtggcgctgccaggatactggatg ctgtttgtgatgaatagcgcgggcgtcccgagcgtagcgagcacgatccgtgtga cccaggccgcagcttgataa 152 GOh2050 MGSSHHHHHHSSGLVPRGSHMGTASAPIGSAIPRNNWAVTCDSAQSGNECNKAID GNKDTFWHTPYGANGDPKPPHTYTIDMKTTQNVNGLSVLPRQDGNQNGWIGRHEV YLSSDGTNWGSPVASGSWFADSTTKYSNFETRPARYVRLVAVTEANGQPWTSIAE INVFQASSYTAPQPGLGRWGPTIDLPIVPAAAAIEPTSGRVLMWSSYRNDAAEGS PGGITLTSSWDPSTGIVSDRTVTVTKHDMFCPGISMDGNGQIVVTGGWDAKKTSL YDSSSDSWIPGPDMQVARGYQSSATMSDGRVFTIGGSFSGGVFEKNGEVYSPSSK TWTSLPNAKVNPMLTADKQGLYMSDNHAWLFGWKKGSVFQAGPSTAMNWYYTSGS GDVKSAGKRQSNRGVAPDAMCGNAVMYDAVKGKILTFGGSPDYTDSDATTNAHII TLGEPGTSPNTVFASNGLYFARTFHTSVVLPDGSTFITGGQRRGIPFEDSTPVFT PEIYVPEQDTFYKQNPNSIVRAYHSISLLLPDGRVFNGGGGLCGDCTTNHFDAQI FTPNYLYDSNGNLATRPKITRTSTQSVKVGGRITISTDSSITKASLIRYGTATHT VNTDQRRIPLTLTNNGGNSYSFQVPSDSGVALPGYWMLFVMNSAGVPSVASTIRV TQAAA 153 GOh2053 atgggcagcagccatcatcatcatcatcacagcagcggcctggtgccgcgcggca gccatatgggtaccgcctctgcccctatcggctcagccatcccgcgcaataactg ggccgtaacgtgcgacagcgcgcagagcggcaacgagtgcaataaagccatcgac ggcaataaagacaccttctggcacacgttttatggcgcaaatggcgacccgaagc caccgcatacctataccattgacatgaaaaccacccagaatgtgaacgggctgtc cgtgctgccgcgccaggacggcaatcagaacggatggatcggccgtcacgaggta tatttaagctccgacggcaccaactggggatccccggtcgcgtcgggcagctggt tcgccgacagcaccaccaagtattccaattttgaaacccgtcctgcacgctacgt gcgcttagtggccgtgcgtgaggcgaacggccagccatggacctcaatcgccgaa atcaatgtattccaagccagctcctataccgcgccgcagccaggacttgggcgtt ggggcccgaccatcgacctgcctatcgtacccgcagccgcggcgattgaaccaac gtcaggccgcgtactgatgtggagcagctaccgtaacgacgcggcggaaggcagc ccgggcggcatcactctgacgtcgagttgggatccatccacgggcatcgtctccg accgcaccgtgaccgtcacgaaacacgacatgttttgcccggggatcagcatgga cggcaacggccagatcgtcgtcacgggcggctgggacgccaagaagacgagcctc tatgacagtagcagcgacagttggatcccggggccggacatgcaggtggcacgcg ggtaccagtccagcgcgaccatgtcagacggccgtgtctttacaatcggcggctc atttagtggcggagtgtttgagaagaatggcgaagtctatagcccctcatccaaa acgtggacgtcacttccgaacgcgaaggtgaatcccatgttaaccgccgacaaac agggcctgtacatgagcgacaaccatgcgtggctgttcggctggaagaaggggag cgtctttcaggcgggcccgtcgaccgcaatgaattggtattacacgtcaggaagc ggggacgtgaaatcagccggcaagcgccagtcgaaccgcggcgtggcgccggacg caatgtgcggcaatgccgtgatgtatgacgcggtcaaaggcaagatcctgacatt tggcgggagtccggactacaccgacagtgacgcgacaaccaatgcccacattatt acccttggggagccggggacgagcccgaacacggtcttcgcgtccaatggcctct atttcgcgcgtacctttcatacgtcggtggtcctgccggacggatcaacctttat caccggcggacagcgccgtggcatccccttcgaagactcgacccccgtctttaca ccggagatttatgtgccggaacaggacacgttttataaacagaatccgaactcga ttgtacgcgcgtatcactccatcagccttcttctcccggacggacgtgtctttaa tggcggaggaggactgtgcggggactgcacgaccaatcattttgacgcgcagatc tttaccccgaattatctgtatgattcaaatgggaatctcgcgacccgtccgaaaa ttacccgtacatcaacccagtccgtcaaagtgggcggccgcattacgatcagtac cgacagcagcattaccaaagcgtcactgattcgttacggcaccgcaacccataca gtcaacacggaccagcgccgtattccgttaaccctgaccaataacggtggcaatt cgtatagcttccaggtaccgtcggactcgggcgtggcgctgccaggatactggat gctgtttgtgatgaatagcgcgggcgtcccgagcgtagcgagcacgatccgtgtg acccaggccgcagcttgataa 154 GOh2053 MGSSHHHHHHSSGLVPRGSHMGTASAPIGSAIPRNNWAVTCDSAQSGNECNKAID GNKDTFWHTFYGANGDPKPPHTYTIDMKTTQNVNGLSVLPRQDGNQNGWIGRHEV YLSSDGTNWGSPVASGSWFADSTTKYSNFETRPARYVRLVAVREANGQPWTSIAE INVFQASSYTAPQPGLGRWGPTIDLPIVPAAAAIEPTSGRVLMWSSYRNDAAEGS PGGITLTSSWDPSTGIVSDRTVTVTKHDMFCPGISMDGNGQIVVTGGWDAKKTSL YDSSSDSWIPGPDMQVARGYQSSATMSDGRVFTIGGSFSGGVFEKNGEVYSPSSK TWTSLPNAKVNPMLTADKQGLYMSDNHAWLFGWKKGSVFQAGPSTAMNWYYTSGS GDVKSAGKRQSNRGVAPDAMCGNAVMYDAVKGKILTFGGSPDYTDSDATTNAHII TLGEPGTSPNTVFASNGLYFARTFHTSVVLPDGSTFITGGQRRGIPFEDSTPVFT PEIYVPEQDTFYKQNPNSIVRAYHSISLLLPDGRVFNGGGGLCGDCTTNHFDAQI FTPNYLYDSNGNLATRPKITRTSTQSVKVGGRITISTDSSITKASLIRYGTATHT VNTDQRRIPLTLTNNGGNSYSFQVPSDSGVALPGYWMLFVMNSAGVPSVASTIRV TQAAA 155 GOh2055 atgggcagcagccatcatcatcatcatcacagcagcggcctggtgccgcgcggca gccatatgggtaccgcctctgcccctatcggctcagccatcccgcgcaataactg ggccgtaacgtgcgacagcgcgcagagcggcaacgagtgcaataaagccatcgac ggcaataaagacaccttctggcacacgttttatggcgcaaatggcgacccgaagc caccgcatacctataccattgacatgaaaaccacccagaatgtgaacgggctgtc cgtgctgccgcgccaggacggcaatcagaacggatggatcggccgtcacgaggta tatttaagctccgacggcaccaactggggatccccggtcgcgtcgggcagctggt tcgccgacagcaccaccaagtattccaattttgaaacccgtcctgcacgctacgt gcgcttagtggccgtgacagaggcgaacggccagccatggacctcaatcgccgaa atcaatgtattccaagccagctcctataccgcgccgcagccaggacttgggcgtt ggggcccgaccatcgacctgcctatcgtacccgcagccggtgcgattgaaccaac gtcaggccgcgtactgatgtggagcagctaccgtaacgacgcggcggaaggcagc ccgggcggcatcactctgacgtcgagttgggatccatccacgggcatcgtctccg accgcaccgtgaccgtcacgaaacacgacatgttttgcccggggatcagcatgga cggcaacggccagatcgtcgtcacgggcggctgggacgccaagaagacgagcctc tatgacagtagcagcgacagttggatcccggggccggacatgcaggtggcacgcg ggtaccagtccagcgcgaccatgtcagacggccgtgtctttacaatcggcggctc atttagtggcggagtgtttgagaagaatggcgaagtctatagcccctcatccaaa acgtggacgtcacttccgaacgcgaaggtgaatcccatgttaaccgccgacaaac agggcctgtacatgagcgacaaccatgcgtggctgttcggctggaagaaggggag cgtctttcaggcgggcccgtcgaccgcaatgaattggtattacacgtcaggaagc ggggacgtgaaatcagccggcaagcgccagtcgaaccgcggcgtggcgccggacg caatgtgcggcaatgccgtgatgtatgacgcggtcaaaggcaagatcctgacatt tgggggagtccggactacaccgacagtgacgcgacaaccaatgcccacattatta cccttggggagccggggacgagcccgaacacggtcttcgcgtccaatggcctcta tttcgcgcgtacctttcatacgtcggtggtcctgccggacggatcaacctttatc accggcggacagcgccgtggcatccccttcgaagactcgacccccgtctttacac cggagatttatgtgccggaacaggacacgttttataaacagaatccgaactcgat tgtacgcgcgtatcactccatcagccttcttctcccggacggacgtgtctttaat ggcggaggaggactgtgcggggactgcacgaccaatcattttgacgcgcagatct ttaccccgaattatctgtatgattcaaatgggaatctcgcgacccgtccgaaaat tacccgtacatcaacccagtccgtcaaagtgggcggccgcattacgatcagtacc gacagcagcattaccaaagcgtcactgattcgttacggcaccgcaacccatacag tcaacacggaccagcgccgtattccgttaaccctgaccaataacggtggcaattc gtatagcttccaggtaccgtcggactcgggcgtggcgctgccaggatactggatg ctgtttgtgatgaatagcgcgggcgtcccgagcgtagcgagcacgatccgtgtga cccaggccgcagcttgataa 156 GOh2055 MGSSHHHHHHSSGLVPRGSHMGTASAPIGSAIPRNNWAVTCDSAQSGNECNKAID GNKDTFWHTFYGANGDPKPPHTYTIDMKTTQNVNGLSVLPRQDGNQNGWIGRHEV YLSSDGTNWGSPVASGSWFADSTTKYSNFETRPARYVRLVAVTEANGQPWTSIAE INVFQASSYTAPQPGLGRWGPTIDLPIVPAAGAIEPTSGRVLMWSSYRNDAAEGS PGGITLTSSWDPSTGIVSDRTVTVTKHDMFCPGISMDGNGQIVVTGGWDAKKTSL YDSSSDSWIPGPDMQVARGYQSSATMSDGRVFTIGGSFSGGVFEKNGEVYSPSSK TWTSLPNAKVNPMLTADKQGLYMSDNHAWLFGWKKGSVFQAGPSTAMNWYYTSGS GDVKSAGKRQSNRGVAPDAMCGNAVMYDAVKGKILTFGGSPDYTDSDATTNAHII TLGEPGTSPNTVFASNGLYFARTFHTSVVLPDGSTFITGGQRRGIPFEDSTPVFT PEIYVPEQDTFYKQNPNSIVRAYHSISLLLPDGRVFNGGGGLCGDCTTNHFDAQI FTPNYLYDSNGNLATRPKITRTSTQSVKVGGRITISTDSSITKASLIRYGTATHT VNTDQRRIPLTLTNNGGNSYSFQVPSDSGVALPGYWMLFVMNSAGVPSVASTIRV TQAAA 157 GOh2056 atgggcagcagccatcatcatcatcatcacagcagcggcctggtgccgcgcggca gccatatgggtaccgcctctgcccctatcggctcagccatcccgcgcaataactg ggccgtaacgtgcgacagcgcgcagagcggcaacgagtgcaataaagccatcgac ggcaataaagacaccttctggcacacgttttatggcgcaaatggcgacccgaagc caccgcatacctataccattgacatgaaaaccacccagaatgtgaacgggctgtc cgtgctgccgcgccaggacggcaatcagaacggatggatcggccgtcacgaggta tatttaagctccgacggcaccaactggggatccccggtcgcgtcgggcagctggt tcgccgacagcaccaccaagtattccaattttgaaacccgtcctgcacgctacgt gcgcttagtggccgtgacagaggcgaacggccagccatggacctcaatcgccgaa atcaatgtattccaagccagctcctataccgcgccgcagccaggacttgggcgtt ggggcccgaccatcgacctgcctatcgtacccgcagccgcggcgattgaaccaac gtcaggccgcgtactgatgtggagcagctaccgtaacgacgcggcggaaggcagc ccgggcggcatcactctgacgtcgagttgggatccatccacgggcatcgtctccg accgcaccgtgaccgtcacgaaacacgacatgttttgcccggggatcagcatgga cggcaacggccagatcgtcgtcagcggcggctgggacgccaagaagacgagcctc tatgacagtagcagcgacagttggatcccggggccggacatgcaggtggcacgcg ggtaccagtccagcgcgaccatgtcagacggccgtgtctttacaatcggcggctc atttagtggcggagtgtttgagaagaatggcgaagtctatagcccctcatccaaa acgtggacgtcacttccgaacgcgaaggtgaatcccatgttaaccgccgacaaac agggcctgtacatgagcgacaaccatgcgtggctgttcggctggaagaaggggag cgtctttcaggcgggcccgtcgaccgcaatgaattggtattacacgtcaggaagc ggggacgtgaaatcagccggcaagcgccagtcgaaccgcggcgtggcgccggacg caatgtgcggcaatgccgtgatgtatgacgcggtcaaaggcaagatcctgacatt tggcgggagtccggactacaccgacagtgacgcgacaaccaatgcccacattatt acccttggggagccggggacgagcccgaacacggtcttcgcgtccaatggcctct atttcgcgcgtacctttcatacgtcggtggtcctgccggacggatcaacctttat caccggcggacagcgccgtggcatccccttcgaagactcgacccccgtctttaca ccggagatttatgtgccggaacaggacacgttttataaacagaatccgaactcga ttgtacgcgcgtatcactccatcagccttcttctcccggacggacgtgtctttaa tggcggaggaggactgtgcggggactgcacgaccaatcattttgacgcgcagatc tttaccccgaattatctgtatgattcaaatgggaatctcgcgacccgtccgaaaa ttacccgtacatcaacccagtccgtcaaagtgggcggccgcattacgatcagtac cgacagcagcattaccaaagcgtcactgattcgttacggcaccgcaacccataca gtcaacacggaccagcgccgtattccgttaaccctgaccaataacggtggcaatt cgtatagcttccaggtaccgtcggactcgggcgtggcgctgccaggatactggat gctgtttgtgatgaatagcgcgggcgtcccgagcgtagcgagcacgatccgtgtg acccaggccgcagcttgataa 158 GOh2056 MGSSHHHHHHSSGLVPRGSHMGTASAPIGSAIPRNNWAVTCDSAQSGNECNKAID GNKDTFWHTFYGANGDPKPPHTYTIDMKTTQNVNGLSVLPRQDGNQNGWIGRHEV YLSSDGTNWGSPVASGSWFADSTTKYSNFETRPARYVRLVAVTEANGQPWTSIAE INVFQASSYTAPQPGLGRWGPTIDLPIVPAAAAIEPTSGRVLMWSSYRNDAAEGS PGGITLTSSWDPSTGIVSDRTVTVTKHDMFCPGISMDGNGQIVVSGGWDAKKTSL YDSSSDSWIPGPDMQVARGYQSSATMSDGRVFTIGGSFSGGVFEKNGEVYSPSSK TWTSLPNAKVNPMLTADKQGLYMSDNHAWLFGWKKGSVFQAGPSTAMNWYYTSGS GDVKSAGKRQSNRGVAPDAMCGNAVMYDAVKGKILTFGGSPDYTDSDATTNAHII TLGEPGTSPNTVFASNGLYFARTFHTSVVLPDGSTFITGGQRRGIPFEDSTPVFT PEIYVPEQDTFYKQNPNSIVRAYHSISLLLPDGRVFNGGGGLCGDCTTNHFDAQI FTPNYLYDSNGNLATRPKITRTSTQSVKVGGRITISTDSSITKASLIRYGTATHT VNTDQRRIPLTLTNNGGNSYSFQVPSDSGVALPGYWMLFVMNSAGVPSVASTIRV TQAAA 159 GOh2057 atgggcagcagccatcatcatcatcatcacagcagcggcctggtgccgcgcggca gccatatgggtaccgcctctgcccctatcggctcagccatcccgcgcaataactg ggccgtaacgtgcgacagcgcgcagagcggcaacgagtgcaataaagccatcgac ggcaataaagacaccttctggcacacgttttatggcgcaaatggcgacccgaagc caccgcatacctataccattgacatgaaaaccacccagaatgtgaacgggctgtc cgtgctgccgcgccaggacggcaatcagaacggatggatcggccgtcacgaggta tatttaagctccgacggcaccaactggggatccccggtcgcgtcgggcagctggt tcgccgacagcaccaccaagtattccaattttgaaacccgtcctgcacgctacgt gcgcttagtggccgtgacagaggcgaacggccagccatggacctcaatcgccgaa atcaatgtattccaagccagctcctataccgcgccgcagccaggacttgggcgtt ggggcccgaccatcgacctgcctatcgtacccgcagccgcggcgattgaaccaac gtcaggccgcgtactgatgtggagcagctaccgtaacgacgcggcggaaggcacc ccgggcggcatcactctgacgtcgagttgggatccatccacgggcatcgtctccg accgcaccgtgaccgtcacgaaacacgacatgttttgcccggggatcagcatgga cggcaacggccagatcgtcgtcacgggcggctgggacgccaagaagacgagcctc tatgacagtagcagcgacagttggatcccggggccggacatgcaggtggcacgcg ggtaccagtccagcgcgaccatgtcagacggccgtgtctttacaatcggcggctc atttagtggcggagtgtttgagaagaatggcgaagtctatagcccctcatccaaa acgtggacgtcacttccgaacgcgaaggtgaatcccatgttaaccgccgacaaac agggcctgtacatgagcgacaaccatgcgtggctgttcggctggaagaaggggag cgtctttcaggcgggcccgtcgaccgcaatgaattggtattacacgtcaggaagc ggggacgtgaaatcagccggcaagcgccagtcgaaccgcggcgtggcgccggacg caatgtgcggcaatgccgtgatgtatgacgcggtcaaaggcaagatcctgacatt tggcgggagtccggactacaccgacagtgacgcgacaaccaatgcccacattatt acccttggggagccggggacgagcccgaacacggtcttcgcgtccaatggcctct atttcgcgcgtacctttcatacgtcggtggtcctgccggacggatcaacctttat caccggcggacagcgccgtggcatccccttcgaagactcgacccccgtctttaca ccggagatttatgtgccggaacaggacacgttttataaacagaatccgaactcga ttgtacgcgcgtatcactccatcagccttcttctcccggacggacgtgtctttaa tggcggaggaggactgtgcggggactgcacgaccaatcattttgacgcgcagatc tttaccccgaattatctgtatgattcaaatgggaatctcgcgacccgtccgaaaa ttacccgtacatcaacccagtccgtcaaagtgggcggccgcattacgatcagtac cgacagcagcattaccaaagcgtcactgattcgttacggcaccgcaacccataca gtcaacacggaccagcgccgtattccgttaaccctgaccaataacggtggcaatt cgtatagcttccaggtaccgtcggactcgggcgtggcgctgccaggatactggat gctgtttgtgatgaatagcgcgggcgtcccgagcgtagcgagcacgatccgtgtg acccaggccgcagcttgataa 160 GOh2057 MGSSHHHHHHSSGLVPRGSHMGTASAPIGSAIPRNNWAVTCDSAQSGNECNKAID GNKDTFWHTFYGANGDPKPPHTYTIDMKTTQNVNGLSVLPRQDGNQNGWIGRHEV YLSSDGTNWGSPVASGSWFADSTTKYSNFETRPARYVRLVAVTEANGQPWTSIAE INVFQASSYTAPQPGLGRWGPTIDLPIVPAAAAIEPTSGRVLMWSSYRNDAAEGT PGGITLTSSWDPSTGIVSDRTVTVTKHDMFCPGISMDGNGQIVVTGGWDAKKTSL YDSSSDSWIPGPDMQVARGYQSSATMSDGRVFTIGGSFSGGVFEKNGEVYSPSSK TWTSLPNAKVNPMLTADKQGLYMSDNHAWLFGWKKGSVFQAGPSTAMNWYYTSGS GDVKSAGKRQSNRGVAPDAMCGNAVMYDAVKGKILTFGGSPDYTDSDATTNAHII TLGEPGTSPNTVFASNGLYFARTFHTSVVLPDGSTFITGGQRRGIPFEDSTPVFT PEIYVPEQDTFYKQNPNSIVRAYHSISLLLPDGRVFNGGGGLCGDCTTNHFDAQI FTPNYLYDSNGNLATRPKITRTSTQSVKVGGRITISTDSSITKASLIRYGTATHT VNTDQRRIPLTLTNNGGNSYSFQVPSDSGVALPGYWMLFVMNSAGVPSVASTIRV TQAAA 161 GOh2058 atgggcagcagccatcatcatcatcatcacagcagcggcctggtgccgcgcggca gccatatgggtaccgcctctgcccctatcggctcagccatcccgcgcaataactg ggccgtaacgtgcgacagcgcgcagagcggcaacgagtgcaataaagccatcgac ggcaataaagacaccttctggcacacgttttatggcgcaaatggcgacccgaagc caccgcatacctataccattgacatgaaaaccacccagaatgtgaacgggctgtc cgtgctgccgcgccaggacggcaatcagaacggatggatcggccgtcacgaggta tatttaagctccgacggcaccaactggggatccccggtcgcgtcgggcagctggt tcgccgacagcaccaccaagtattccaattttgaaacccgtcctgcacgctacgt gcgcttagtggccgtgacagaggcgaacggccagccatggacctcaatcgccgaa atcaatgtattccaagccagctcctataccgcgccgcagccaggacttgggcgtt ggggcccgaccatcgacctgcctatcgtacccgcagccgcggcgattgaaccaac gtcaggccgcgtactgatgtggagcagctaccgtagcgacgcggcggaaggcagc ccgggcggcatcactctgacgtcgagttgggatccatccacgggcatcgtctccg accgcaccgtgaccgtcacgaaacacgacatgttttgcccggggatcagcatgga cggcaacggccagatcgtcgtcacgggcggctgggacgccaagaagacgagcctc tatgacagtagcagcgacagttggatcccggggccggacatgcaggtggcacgcg ggtaccagtccagcgcgaccatgtcagacggccgtgtctttacaatcggcggctc atttagtggcggagtgtttgagaagaatggcgaagtctatagcccctcatccaaa acgtggacgtcacttccgaacgcgaaggtgaatcccatgttaaccgccgacaaac agggcctgtacatgagcgacaaccatgcgtggctgttcggctggaagaaggggag cgtctttcaggcgggcccgtcgaccgcaatgaattggtattacacgtcaggaagc ggggacgtgaaatcagccggcaagcgccagtcgaaccgcggcgtggcgccggacg caatgtgcggcaatgccgtgatgtatgacgcggtcaaaggcaagatcctgacatt tggcgggagtccggactacaccgacagtgacgcgacaaccaatgcccacattatt acccttggggagccggggacgagcccgaacacggtcttcgcgtccaatggcctct atttcgcgcgtacctttcatacgtcggtggtcctgccggacggatcaacctttat caccggcggacagcgccgtggcatccccttcgaagactcgacccccgtctttaca ccggagatttatgtgccggaacaggacacgttttataaacagaatccgaactcga ttgtacgcgcgtatcactccatcagccttcttctcccggacggacgtgtctttaa tggcggaggaggactgtgcggggactgcacgaccaatcattttgacgcgcagatc tttaccccgaattatctgtatgattcaaatgggaatctcgcgacccgtccgaaaa ttacccgtacatcaacccagtccgtcaaagtgggcggccgcattacgatcagtac cgacagcagcattaccaaagcgtcactgattcgttacggcaccgcaacccataca gtcaacacggaccagcgccgtattccgttaaccctgaccaataacggtggcaatt cgtatagcttccaggtaccgtcggactcgggcgtggcgctgccaggatactggat gctgtttgtgatgaatagcgcgggcgtcccgagcgtagcgagcacgatccgtgtg acccaggccgcagcttgataa 162 GOh2058 MGSSHHHHHHSSGLVPRGSHMGTASAPIGSAIPRNNWAVTCDSAQSGNECNKAID GNKDTFWHTFYGANGDPKPPHTYTIDMKTTQNVNGLSVLPRQDGNQNGWIGRHEV YLSSDGTNWGSPVASGSWFADSTTKYSNFETRPARYVRLVAVTEANGQPWTSIAE INVFQASSYTAPQPGLGRWGPTIDLPIVPAAAAIEPTSGRVLMWSSYRSDAAEGS PGGITLTSSWDPSTGIVSDRTVTVTKHDMFCPGISMDGNGQIVVTGGWDAKKTSL YDSSSDSWIPGPDMQVARGYQSSATMSDGRVFTIGGSFSGGVFEKNGEVYSPSSK TWTSLPNAKVNPMLTADKQGLYMSDNHAWLFGWKKGSVFQAGPSTAMNWYYTSGS GDVKSAGKRQSNRGVAPDAMCGNAVMYDAVKGKILTFGGSPDYTDSDATTNAHII TLGEPGTSPNTVFASNGLYFARTFHTSVVLPDGSTFITGGQRRGIPFEDSTPVFT PEIYVPEQDTFYKQNPNSIVRAYHSISLLLPDGRVFNGGGGLCGDCTTNHFDAQI FTPNYLYDSNGNLATRPKITRTSTQSVKVGGRITISTDSSITKASLIRYGTATHT VNTDQRRIPLTLTNNGGNSYSFQVPSDSGVALPGYWMLFVMNSAGVPSVASTIRV TQAAA 163 GOh2061 atgggcagcagccatcatcatcatcatcacagcagcggcctggtgccgcgcggca gccatatgggtaccgcctctgcccctatcggctcagccatcccgcgcaataactg ggccgtaacgtgcgacagcgcgcagagcggcaacgagtgcaataaagccatcgac ggcaataaagacaccttctggcacacgttttatggcgcaaatggcgacccgaagc caccgcatacctataccattgacatgaaaaccacccagaatgtgaacgggctgtc cgtgctgccgcgccaggacggcaatcagaacggatggatcggccgtcacgaggta tatttaagctccgacggcaccaactggggatccccggtcgcgtcgggcagctggt tcgccgacagcaccaccaagtattccaattttgaaacccgtcctgcacgctacgt gcgcttagtggccgtgacagaggcgaacggccagccatggacctcaatcgccgaa atcaatgtattccaagccagctcctataccgcgccgcagccaggacttgggcgtt ggggcccgaccatcgacctgcctatcgtacccgcagccgcggcgattgaaccaac gtcaggccgcgtactgatgtggagcagctaccgtaacgacgcggcggaaggcagc ccgggcggcatcactctgacgtcgagttgggatccatccacgggcatcgtctccg accgcaccgtgaccgtcacgaaacacgacatgttttgcccggggatcagcatgga cggcaacggccagatcgtcgtcacgggcggctgggacgccaagaagacgagcctc tatgacagtagcagcgacagttggatcccggggccggacatgcaggtggcacgcg ggtaccagtccagcgcgaccatgtcagacggccgtgtctttacaatcggcggctc atttagtggcggagtgtttgagaagaatggcgaagtctatagcccctcatccaaa acgtggacgtcacttccgaacgcgaaggtgaatcccatgttaaccgccgacaaac agggcctgtacatgagcgacaaccatgcgtggctgttcggctggaagaaggggag cgtctttcaggcgggcccgtcgaccgcaatgaattggtattacacgtcaggaagc ggggacgtgaaatcagccggcaagcgccagtcgaaccgcggcgtggcgccggacg caatgtgcggcaatgccgtgatgtatgacgcggtcaaaggcaagatcctgacatt tggcgggagtccggactacaccgacagtgacgcgacaaccaatgcccacattatt acccttggggagccggggacgagcccgaacacggtcttcgcgtccaatggcctct atttcgcgcgtacctttcatacgtcggtggtcctgccggacggatcaacctttat caccggcggacagcgccgtggcgcacccttcgaagactcgacccccgtctttaca ccggagatttatgtgccggaacaggacacgttttataaacagaatccgaactcga ttgtacgcgcgtatcactccatcagccttcttctcccggacggacgtgtctttaa tggcggaggaggactgtgcggggactgcacgaccaatcattttgacgcgcagatc tttaccccgaattatctgtatgattcaaatgggaatctcgcgacccgtccgaaaa ttacccgtacatcaacccagtccgtcaaagtgggcggccgcattacgatcagtac cgacagcagcattaccaaagcgtcactgattcgttacggcaccgcaacccataca gtcaacacggaccagcgccgtattccgttaaccctgaccaataacggtggcaatt cgtatagcttccaggtaccgtcggactcgggcgtggcgctgccaggatactggat gctgtttgtgatgaatagcgcgggcgtcccgagcgtagcgagcacgatccgtgtg acccaggccgcagcttgataa 164 GOh2061 MGSSHHHHHHSSGLVPRGSHMGTASAPIGSAIPRNNWAVTCDSAQSGNECNKAID GNKDTFWHTFYGANGDPKPPHTYTIDMKTTQNVNGLSVLPRQDGNQNGWIGRHEV YLSSDGTNWGSPVASGSWFADSTTKYSNFETRPARYVRLVAVTEANGQPWTSIAE INVFQASSYTAPQPGLGRWGPTIDLPIVPAAAAIEPTSGRVLMWSSYRNDAAEGS PGGITLTSSWDPSTGIVSDRTVTVTKHDMFCPGISMDGNGQIVVTGGWDAKKTSL YDSSSDSWIPGPDMQVARGYQSSATMSDGRVFTIGGSFSGGVFEKNGEVYSPSSK TWTSLPNAKVNPMLTADKQGLYMSDNHAWLFGWKKGSVFQAGPSTAMNWYYTSGS GDVKSAGKRQSNRGVAPDAMCGNAVMYDAVKGKILTFGGSPDYTDSDATTNAHII TLGEPGTSPNTVFASNGLYFARTFHTSVVLPDGSTFITGGQRRGAPFEDSTPVFT PEIYVPEQDTFYKQNPNSIVRAYHSISLLLPDGRVFNGGGGLCGDCTTNHFDAQI FTPNYLYDSNGNLATRPKITRTSTQSVKVGGRITISTDSSITKASLIRYGTATHT VNTDQRRIPLTLTNNGGNSYSFQVPSDSGVALPGYWMLFVMNSAGVPSVASTIRV TQAAA 165 GOh2064 atgggcagcagccatcatcatcatcatcacagcagcggcctggtgccgcgcggca gccatatgggtaccgcctctgcccctatcggctcagccatcccgcgcaataactg ggccgtaacgtgcgacagcgcgcagagcggcaacgagtgcaataaagccatcgac ggcaataaagacaccttctggcacacgttttatggcgcaaatggcgacccgaagc caccgcatacctataccattgacatgaaaaccacccagaatgtgaacgggctgtc cgtgctgccgcgccaggacggcaatcagaacggatggatcggccgtcacgaggta tatttaagctccgacggcaccaactggggatccccggtcgcgtcgggcagctggt tcgccgacagcaccaccaagtattccaattttgaaacccgtcctgcacgctacgt gcgcttagtggccgtgacagaggcgaacggccagccatggacctcaatcgccgaa atcaatgtattccaagccagctcctataccgcgccgcagccaggacttgggcgtt ggggcccgaccatcgacctgcctatcgtacccgcagccgcggcgattgaaccaac gtcaggccgcgtactgatgtggagcagctaccgtcgtgacgcggcggaaggcagc ccgggggcatcactctgacgtcgagttgggatccatccacgggcatcgtctccga ccgcaccgtgaccgtcacgaaacacgacatgttttgcccggggatcagcatggac ggcaacggccagatcgtcgtcacgggcggctgggacgccaagaagacgagcctct atgacagtagcagcgacagttggatcccggggccggacatgcaggtggcacgcgg gtaccagtccagcgcgaccatgtcagacggccgtgtctttacaatcggcggctca tttagtggcggagtgtttgagaagaatggcgaagtctatagcccctcatccaaaa cgtggacgtcacttccgaacgcgaaggtgaatcccatgttaaccgccgacaaaca gggcctgtacatgagcgacaaccatgcgtggctgttcggctggaagaaggggagc gtctttcaggcgggcccgtcgaccgcaatgaattggtattacacgtcaggaagcg gggacgtgaaatcagccggcaagcgccagtcgaaccgcggcgtggcgccggacgc aatgtgcggcaatgccgtgatgtatgacgcggtcaaaggcaagatcctgacattt ggcgggagtccggactacaccgacagtgacgcgacaaccaatgcccacattatta cccttggggagccggggacgagcccgaacacggtcttcgcgtccaatggcctcta tttcgcgcgtacctttcatacgtcggtggtcctgccggacggatcaacctttatc accggcggacagcgccgtggcatccccttcgaagactcgacccccgtctttacac cggagatttatgtgccggaacaggacacgttttataaacagaatccgaactcgat tgtacgcgcgtatcactccatcagccttcttctcccggacggacgtgtctttaat ggcggaggaggactgtgcggggactgcacgaccaatcattttgacgcgcagatct ttaccccgaattatctgtatgattcaaatgggaatctcgcgacccgtccgaaaat tacccgtacatcaacccagtccgtcaaagtgggcggccgcattacgatcagtacc gacagcagcattaccaaagcgtcactgattcgttacggcaccgcaacccatacag tcaacacggaccagcgccgtattccgttaaccctgaccaataacggtggcaattc gtatagcttccaggtaccgtcggactcgggcgtggcgctgccaggatactggatg ctgtttgtgatgaatagcgcgggcgtcccgagcgtagcgagcacgatccgtgtga cccaggccgcagcttgataa 166 GOh2064 MGSSHHHHHHSSGLVPRGSHMGTASAPIGSAIPRNNWAVTCDSAQSGNECNKAID GNKDTFWHTFYGANGDPKPPHTYTIDMKTTQNVNGLSVLPRQDGNQNGWIGRHEV YLSSDGTNWGSPVASGSWFADSTTKYSNFETRPARYVRLVAVTEANGQPWTSIAE INVFQASSYTAPQPGLGRWGPTIDLPIVPAAAAIEPTSGRVLMWSSYRRDAAEGS PGGITLTSSWDPSTGIVSDRTVTVTKHDMFCPGISMDGNGQIVVTGGWDAKKTSL YDSSSDSWIPGPDMQVARGYQSSATMSDGRVFTIGGSFSGGVFEKNGEVYSPSSK TWTSLPNAKVNPMLTADKQGLYMSDNHAWLFGWKKGSVFQAGPSTAMNWYYTSGS GDVKSAGKRQSNRGVAPDAMCGNAVMYDAVKGKILTFGGSPDYTDSDATTNAHII TLGEPGTSPNTVFASNGLYFARTFHTSVVLPDGSTFITGGQRRGIPFEDSTPVFT PEIYVPEQDTFYKQNPNSIVRAYHSISLLLPDGRVFNGGGGLCGDCTTNHFDAQI FTPNYLYDSNGNLATRPKITRTSTQSVKVGGRITISTDSSITKASLIRYGTATHT VNTDQRRIPLTLTNNGGNSYSFQVPSDSGVALPGYWMLFVMNSAGVPSVASTIRV TQAAA 167 GOh2066 atgggcagcagccatcatcatcatcatcacagcagcggcctggtgccgcgcggca gccatatgggtaccgcctctgcccctatcggctcagccatcccgcgcaataactg ggccgtaacgtgcgacagcgcgcagagcggcaacgagtgcaataaagccatcgac ggcaataaagacaccttctggcacacgttttatggcgcaaatggcgacccgaagc caccgcatacctataccattgacatgaaaaccacccagaatgtgaacgggctgtc cgtgctgccgcgccaggacggcaatcagaacggatggatcggccgtcacgaggta tatttaagctccgacggcaccaactggggatccccggtcgcgtcgggcagctggt tcgccgacagcaccaccaagtattccaattttgaaacccgtcctgcacgctacgt gcgcttagtggccgtgacagaggcgaacggccagccatggacctcaatcgccgaa atcaatgtattccaagccagctcctataccgcgccgcagccaggacttgggcgtt ggggcccgaccatcgacctgcctatcgtacccgcagccgcggcgattgaaccaac gtcaggccgcgtactgatgtggagcagctaccgtaacgacgcggcggaaggcagc ccgggggcatcactctgacgtcgagttgggatccatccacgggcatcgtctccga ccgcaccgtgaccgtcacgaaacacgacatgttttgcccggggatcagcatggac ggcaacggccagatcgtcgtcacgggcggctggaatgccaagaagacgagcctct atgacagtagcagcgacagttggatcccggggccggacatgcaggtggcacgcgg gtaccagtccagcgcgaccatgtcagacggccgtgtctttacaatcggcggctca tttagtggcggagtgtttgagaagaatggcgaagtctatagcccctcatccaaaa cgtggacgtcacttccgaacgcgaaggtgaatcccatgttaaccgccgacaaaca gggcctgtacatgagcgacaaccatgcgtggctgttcggctggaagaaggggagc gtctttcaggcgggcccgtcgaccgcaatgaattggtattacacgtcaggaagcg gggacgtgaaatcagccggcaagcgccagtcgaaccgcggcgtggcgccggacgc aatgtgcggcaatgccgtgatgtatgacgcggtcaaaggcaagatcctgacattt ggcgggagtccggactacaccgacagtgacgcgacaaccaatgcccacattatta cccttggggagccggggacgagcccgaacacggtcttcgcgtccaatggcctcta tttcgcgcgtacctttcatacgtcggtggtcctgccggacggatcaacctttatc accggcggacagcgccgtggcatccccttcgaagactcgacccccgtctttacac cggagatttatgtgccggaacaggacacgttttataaacagaatccgaactcgat tgtacgcgcgtatcactccatcagccttcttctcccggacggacgtgtctttaat ggcggaggaggactgtgcggggactgcacgaccaatcattttgacgcgcagatct ttaccccgaattatctgtatgattcaaatgggaatctcgcgacccgtccgaaaat tacccgtacatcaacccagtccgtcaaagtgggcggccgcattacgatcagtacc gacagcagcatcaccaaagcgtcactgattcgttacggcaccgcaacccatacag tcaacacggaccagcgccgtattccgttaaccctgaccaataacggtggcaattc gtatagcttccaggtaccgtcggactcgggcgtggcgctgccaggatactggatg ctgtttgtgatgaatagcgcgggcgtcccgagcgtagcgagcacgatccgtgtga cccaggccgcagcttgataa 168 GOh2066 MGSSHHHHHHSSGLVPRGSHMGTASAPIGSAIPRNNWAVTCDSAQSGNECNKAID GNKDTFWHTFYGANGDPKPPHTYTIDMKTTQNVNGLSVLPRQDGNQNGWIGRHEV YLSSDGTNWGSPVASGSWFADSTTKYSNFETRPARYVRLVAVTEANGQPWTSIAE INVFQASSYTAPQPGLGRWGPTIDLPIVPAAAAIEPTSGRVLMWSSYRNDAAEGS PGGITLTSSWDPSTGIVSDRTVTVTKHDMFCPGISMDGNGQIVVTGGWNAKKTSL YDSSSDSWIPGPDMQVARGYQSSATMSDGRVFTIGGSFSGGVFEKNGEVYSPSSK TWTSLPNAKVNPMLTADKQGLYMSDNHAWLFGWKKGSVFQAGPSTAMNWYYTSGS GDVKSAGKRQSNRGVAPDAMCGNAVMYDAVKGKILTFGGSPDYTDSDATTNAHII TLGEPGTSPNTVFASNGLYFARTFHTSVVLPDGSTFITGGQRRGIPFEDSTPVFT PEIYVPEQDTFYKQNPNSIVRAYHSISLLLPDGRVFNGGGGLCGDCTTNHFDAQI FTPNYLYDSNGNLATRPKITRTSTQSVKVGGRITISTDSSITKASLIRYGTATHT VNTDQRRIPLTLTNNGGNSYSFQVPSDSGVALPGYWMLFVMNSAGVPSVASTIRV TQAAA 169 GOh2067 atgggcagcagccatcatcatcatcatcacagcagcggcctggtgccgcgcggca gccatatgggtaccgcctctgcccctatcggctcagccatcccgcgcaataactg ggccgtaacgtgcgacagcgcgcagagcggcaacgagtgcaataaagccatcgac ggcaataaagacaccttctggcacacgttttatggcgcaaatggcgacccgaagc caccgcatacctataccattgacatgaaaaccacccagaatgtgaacgggctgtc cgtgctgccgcgccaggacggcaatcagaacggatggatcggccgtcacgaggta tatttaagctccgacggcaccaactggggatccccggtcgcgtcgggcagctggt tcgccgacagcaccaccaagtattccaattttgaaacccgtcctgcacgctacgt gcgcttagtggccgtgacagaggcgaacggccagccatggacctcaatcgccgaa atcaatgtattccaagccagctcctataccgcgccgcagccaggacttgggcgtt ggggcccgaccatcgacctgcctatcgtacccgcagccgcggcgattgaaccaac gtcaggccgcgtactgatgtggagcagctaccgtaacgacgcggcggaaggcagc ccgggcggcatcactctgacgtcgagttgggatccatccacgggcatcgtctccg accgcaccgtgaccgtcacgaaacacgacatgttttgcccggggatcagcatgga cggcaacggccagatcgtcgtcacgggcggctgggacgccaagaagacgagcctc tatgacagtagcagcgacagttggatcccggggccggacatgcaggtggcacgcg ggtaccagtccagcgcgaccatgtcagacggccgtgtctttacaatcggcggctc atttagtggcggagtgtttgagaagaatggcgaagtctatagcccctcatccaaa acgtggacgtcacttccgaacgcgaaggtgaatcccatgttaaccgccgacaaac agggcctgtacatgagcgacaaccatgcgtggctgttcggctggaagaaggggag cgtctttcaggcgggcccgtcgaccgcaatgaattggtattacacgtcaggaagc ggggacgtgaaatcagccggcaagcgccagtcgaaccgcggcgtggcgccggacg caatgtgcggcaatgccgtgatgtatgacgcggtcaaaggcaagatcctgacatt tggcgggagtccggactacaccgacagtgacgcgacaaccaatgcccacattatt acccttggggagccggggacgagcccgaacacggtcttcgcgtccaatggcctct atttcgcgcgtacctttcatacgtcggtggtcctgccggacggatcaacctttat caccggcggacagcgccgtggccgtcccttcgaagactcgacccccgtctttaca ccggagatttatgtgccggaacaggacacgttttataaacagaatccgaactcga ttgtacgcgcgtatcactccatcagccttcttctcccggacggacgtgtctttaa tggcggaggaggactgtgcggggactgcacgaccaatcattttgacgcgcagatc tttaccccgaattatctgtatgattcaaatgggaatctcgcgacccgtccgaaaa ttacccgtacatcaacccagtccgtcaaagtgggcggccgcattacgatcagtac cgacagcagcattaccaaagcgtcactgattcgttacggcaccgcaacccataca gtcaacacggaccagcgccgtattccgttaaccctgaccaataacggtggcaatt cgtatagcttccaggtaccgtcggactcgggcgtggcgctgccaggatactggat gctgtttgtgatgaatagcgcgggcgtcccgagcgtagcgagcacgatccgtgtg acccaggccgcagcttgataa 170 GOh2067 MGSSHHHHHHSSGLVPRGSHMGTASAPIGSAIPRNNWAVTCDSAQSGNECNKAID GNKDTFWHTFYGANGDPKPPHTYTIDMKTTQNVNGLSVLPRQDGNQNGWIGRHEV YLSSDGTNWGSPVASGSWFADSTTKYSNFETRPARYVRLVAVTEANGQPWTSIAE INVFQASSYTAPQPGLGRWGPTIDLPIVPAAAAIEPTSGRVLMWSSYRNDAAEGS PGGITLTSSWDPSTGIVSDRTVTVTKHDMFCPGISMDGNGQIVVTGGWDAKKTSL YDSSSDSWIPGPDMQVARGYQSSATMSDGRVFTIGGSFSGGVFEKNGEVYSPSSK TWTSLPNAKVNPMLTADKQGLYMSDNHAWLFGWKKGSVFQAGPSTAMNWYYTSGS GDVKSAGKRQSNRGVAPDAMCGNAVMYDAVKGKILTFGGSPDYTDSDATTNAHII TLGEPGTSPNTVFASNGLYFARTFHTSVVLPDGSTFITGGQRRGRPFEDSTPVFT PEIYVPEQDTFYKQNPNSIVRAYHSISLLLPDGRVFNGGGGLCGDCTTNHFDAQI FTPNYLYDSNGNLATRPKITRTSTQSVKVGGRITISTDSSITKASLIRYGTATHT VNTDQRRIPLTLTNNGGNSYSFQVPSDSGVALPGYWMLFVMNSAGVPSVASTIRV TQAAA 171 GOh2068 atgggcagcagccatcatcatcatcatcacagcagcggcctggtgccgcgcggca gccatatgggtaccgcctctgcccctatcggctcagccatcccgcgcaataactg ggccgtaacgtgcgacagcgcgcagagcggcaacgagtgcaataaagccatcgac ggcaataaagacaccttctggcacacgttttatggcgcaaatggcgacccgaagc caccgcatacctataccattgacatgaaaaccacccagaatgtgaacgggctgtc cgtgctgccgcgccaggacggcaatcagaacggatggatcggccgtcacgaggta tatttaagctccgacggcaccaactggggatccccggtcgcgtcgggcagctggt tcgccgacagcaccaccaagtattccaattttgaaacccgtcctgcacgctacgt gcgcttagtggccgtgacagaggcgaacggccagccatggacctcaatcgccgaa atcaatgtattccaagccagctcctataccgcgccgcagccaggacttgggcgtt ggggcccgaccatcgacctgcctatcgtacccgcagccgcggcgattgaaccaac gtcaggccgcgtactgatgtggagcagctaccgtaacgacgcggcggaaggcagc ccgggcggcatcactctgacgtcgagttgggatccatccacgggcatcgtctccg accgcaccgtgaccgtcacgaaacacgacatgttttgcccggggatcagcatgga cggcaacggccagatcgtcgtcacgggcggctgggacgccaagaagacgagcctc tatgacagtagcagcgacagttggatcccggggccggacatgcaggtggcacgcg ggtaccagtccagcgcgaccatgtcagacggccgtgtctttacaatcggcggctc atttagtggcggagtgtttgagaagaatggcgaagtctatagcccctcatccaaa acgtggacgtcacttccgaacgcgaaggtgaatcccatgttaaccgccgacaaac agggcctgtacatgagcgacaaccatgcgtggctgttcggctggaagaaggggag cgtctttcaggcgggcccgtcgaccgcaatgaattggtattacacgtcaggaagc ggggacgtgaaatcagccggcaagcgccagtcgaaccgcggcgtggcgccggacg caatgtgcggcaatgccgtgatgtatgacgcggtcaaaggcaagatcctgacatt tggcgggagtccggactacaccgacagtgacgcgacaaccaatgcccacattatt acccttggggagccggggacgagcccgaacacggtcttcgcgtccaatggcctct atttcgcgcgtacctttcatacgtcggtggtcctgccggacggatcaacctttat caccggcggacagcgccgtggcaaacccttcgaagactcgacccccgtctttaca ccggagatttatgtgccggaacaggacacgttttataaacagaatccgaactcga ttgtacgcgcgtatcactccatcagccttcttctcccggacggacgtgtctttaa tggcggaggaggactgtgcggggactgcacgaccaatcattttgacgcgcagatc tttaccccgaattatctgtatgattcaaatgggaatctcgcgacccgtccgaaaa ttacccgtacatcaacccagtccgtcaaagtgggcggccgcattacgatcagtac cgacagcagcattaccaaagcgtcactgattcgttacggcaccgcaacccataca gtcaacacggaccagcgccgtattccgttaaccctgaccaataacggtggcaatt cgtatagcttccaggtaccgtcggactcgggcgtggcgctgccaggatactggat gctgtttgtgatgaatagcgcgggcgtcccgagcgtagcgagcacgatccgtgtg acccaggccgcagcttgataa 172 GOh2068 MGSSHHHHHHSSGLVPRGSHMGTASAPIGSAIPRNNWAVTCDSAQSGNECNKAID GNKDTFWHTFYGANGDPKPPHTYTIDMKTTQNVNGLSVLPRQDGNQNGWIGRHEV YLSSDGTNWGSPVASGSWFADSTTKYSNFETRPARYVRLVAVTEANGQPWTSIAE INVFQASSYTAPQPGLGRWGPTIDLPIVPAAAAIEPTSGRVLMWSSYRNDAAEGS PGGITLTSSWDPSTGIVSDRTVTVTKHDMFCPGISMDGNGQIVVTGGWDAKKTSL YDSSSDSWIPGPDMQVARGYQSSATMSDGRVFTIGGSFSGGVFEKNGEVYSPSSK TWTSLPNAKVNPMLTADKQGLYMSDNHAWLFGWKKGSVFQAGPSTAMNWYYTSGS GDVKSAGKRQSNRGVAPDAMCGNAVMYDAVKGKILTFGGSPDYTDSDATTNAHII TLGEPGTSPNTVFASNGLYFARTFHTSVVLPDGSTFITGGQRRGKPFEDSTPVFT PEIYVPEQDTFYKQNPNSIVRAYHSISLLLPDGRVFNGGGGLCGDCTTNHFDAQI FTPNYLYDSNGNLATRPKITRTSTQSVKVGGRITISTDSSITKASLIRYGTATHT VNTDQRRIPLTLTNNGGNSYSFQVPSDSGVALPGYWMLFVMNSAGVPSVASTIRV TQAAA 173 GOh2070 atgggcagcagccatcatcatcatcatcacagcagcggcctggtgccgcgcggca gccatatgggtaccgcctctgcccctatcggctcagccatcccgcgcaataactg ggccgtaacgtgcgacagcgcgcagagcggcaacgagtgcaataaagccatcgac ggcaataaagacaccttctggcacacgttttatggcgcaaatggcgacccgaagc caccgcatacctataccattgacatgaaaaccacccagaatgtgaacgggctgtc cgtgctgccgcgccaggacggcaatcagaacggatggatcggccgtcacgaggta tatttaagctccgacggcaccaactggggatccccggtcgcgtcgggcagctggt tcgccgacagcaccaccaagtattccaattttgaaacccgtcctgcacgctacgt gcgcttagtggccgtgacagaggcgaacggccagccatggacctcaatcgccgaa atcaatgtattccaagccagctcctataccgcgccgcagccaggacttgggcgtt ggggcccgaccatcgacctgcctatcgtacccgcagccgcggcgattgaaccaac gtcaggccgcgtactgatgtggagcagctaccgtaacgacgcggcggaaggcagc ccgggggcatcactctgacgtcgagttgggatccatccacgggcatcgtctccga acgcaccgtgaccgtcacgaaacacgacatgttttgcccggggatcagcatggac ggcaacggccagatcgtcgtcacgggcggctgggacgccaagaagacgagcctct atgacagtagcagcgacagttggatcccggggccggacatgcaggtggcacgcgg gtaccagtccagcgcgaccatgtcagacggccgtgtctttacaatcggcggctca tttagtggcggagtgtttgagaagaatggcgaagtctatagcccctcatccaaaa cgtggacgtcacttccgaacgcgaaggtgaatcccatgttaaccgccgacaaaca gggcctgtacatgagcgacaaccatgcgtggctgttcggctggaagaaggggagc gtctttcaggcgggcccgtcgaccgcaatgaattggtattacacgtcaggaagcg gggacgtgaaatcagccggcaagcgccagtcgaaccgcggcgtggcgccggacgc aatgtgcggcaatgccgtgatgtatgacgcggtcaaaggcaagatcctgacattt ggcgggagtccggactacaccgacagtgacgcgacaaccaatgcccacattatta cccttggggagccggggacgagcccgaacacggtcttcgcgtccaatggcctcta tttcgcgcgtacctttcatacgtcggtggtcctgccggacggatcaacctttatc accggcggacagcgccgtggcatccccttcgaagactcgacccccgtctttacac cggagatttatgtgccggaacaggacacgttttataaacagaatccgaactcgat tgtacgcgcgtatcactccatcagccttcttctcccggacggacgtgtctttaat ggcggaggaggactgtgcggggactgcacgaccaatcattttgacgcgcagatct ttaccccgaattatctgtatgattcaaatgggaatctcgcgacccgtccgaaaat tacccgtacatcaacccagtccgtcaaagtgggcggccgcattacgatcagtacc gacagcagcattaccaaagcgtcactgattcgttacggcaccgcaacccatacag tcaacacggaccagcgccgtattccgttaaccctgaccaataacggtggcaattc gtatagcttccaggtaccgtcggactcgggcgtggcgctgccaggatactggatg ctgtttgtgatgaatagcgcgggcgtcccgagcgtagcgagcacgatccgtgtga cccaggccgcagcttgataa 174 GOh2070 MGSSHHHHHHSSGLVPRGSHMGTASAPIGSAIPRNNWAVTCDSAQSGNECNKAID GNKDTFWHTFYGANGDPKPPHTYTIDMKTTQNVNGLSVLPRQDGNQNGWIGRHEV YLSSDGTNWGSPVASGSWFADSTTKYSNFETRPARYVRLVAVTEANGQPWTSIAE INVFQASSYTAPQPGLGRWGPTIDLPIVPAAAAIEPTSGRVLMWSSYRNDAAEGS PGGITLTSSWDPSTGIVSERTVTVTKHDMFCPGISMDGNGQIVVTGGWDAKKTSL YDSSSDSWIPGPDMQVARGYQSSATMSDGRVFTIGGSFSGGVFEKNGEVYSPSSK TWTSLPNAKVNPMLTADKQGLYMSDNHAWLFGWKKGSVFQAGPSTAMNWYYTSGS GDVKSAGKRQSNRGVAPDAMCGNAVMYDAVKGKILTFGGSPDYTDSDATTNAHII TLGEPGTSPNTVFASNGLYFARTFHTSVVLPDGSTFITGGQRRGIPFEDSTPVFT PEIYVPEQDTFYKQNPNSIVRAYHSISLLLPDGRVFNGGGGLCGDCTTNHFDAQI FTPNYLYDSNGNLATRPKITRTSTQSVKVGGRITISTDSSITKASLIRYGTATHT VNTDQRRIPLTLTNNGGNSYSFQVPSDSGVALPGYWMLFVMNSAGVPSVASTIRV TQAAA 175 GOh2071 atgggcagcagccatcatcatcatcatcacagcagcggcctggtgccgcgcggca gccatatgggtaccgcctctgcccctatcggctcagccatcccgcgcaataactg ggccgtaacgtgcgacagcgcgcagagcggcaacgagtgcaataaagccatcgac ggcaataaagacaccttctggcacacgttttatggcgcaaatggcgacccgaagc caccgcatacctataccattgacatgaaaaccacccagaatgtgaacgggctgtc cgtgctgccgcgccaggacggcaatcagaacggatggatcggccgtcacgaggta tatttaagctccgacggcgataactggggatccccggtcgcgtcgggcagctggt tcgccgacagcaccaccaagtattccaattttgaaacccgtcctgcacgctacgt gcgcttagtggccgtgacagaggcgaacggccagccatggacctcaatcgccgaa atcaatgtattccaagccagctcctataccgcgccgcagccaggacttgggcgtt ggggcccgaccatcgacctgcctatcgtacccgcagccgcggcgattgaaccaac gtcaggccgcgtactgatgtggagcagctaccgtaacgacgcggcggaaggcagc ccgggcggcatcactctgacgtcgagttgggatccatccacgggcatcgtctccg accgcaccgtgaccgtcacgaaacacgacatgttttgcccggggatcagcatgga cggcaacggccagatcgtcgtcacgggcggctgggacgccaagaagacgagcctc tatgacagtagcagcgacagttggatcccggggccggacatgcaggtggcacgcg ggtaccagtccagcgcgaccatgtcagacggccgtgtctttacaatcggcggctc atttagtggcggagtgtttgagaagaatggcgaagtctatagcccctcatccaaa acgtggacgtcacttccgaacgcgaaggtgaatcccatgttaaccgccgacaaac agggcctgtacatgagcgacaaccatgcgtggctgttcggctggaagaaggggag cgtctttcaggcgggcccgtcgaccgcaatgaattggtattacacgtcaggaagc ggggacgtgaaatcagccggcaagcgccagtcgaaccgcggcgtggcgccggacg caatgtgcggcaatgccgtgatgtatgacgcggtcaaaggcaagatcctgacatt tgggggagtccggactacaccgacagtgacgcgacaaccaatgcccacattatta cccttggggagccggggacgagcccgaacacggtcttcgcgtccaatggcctcta tttcgcgcgtacctttcatacgtcggtggtcctgccggacggatcaacctttatc accggcggacagcgccgtggcatccccttcgaagactcgacccccgtctttacac cggagatttatgtgccggaacaggacacgttttataaacagaatccgaactcgat tgtacgcgcgtatcactccatcagccttcttctcccggacggacgtgtctttaat ggcggaggaggactgtgcggggactgcacgaccaatcattttgacgcgcagatct ttaccccgaattatctgtatgattcaaatgggaatctcgcgacccgtccgaaaat tacccgtacatcaacccagtccgtcaaagtgggcggccgcattacgatcagtacc gacagcagcattaccaaagcgtcactgattcgttacggcaccgcaacccatacag tcaacacggaccagcgccgtattccgttaaccctgaccaataacggtggcaattc gtatagcttccaggtaccgtcggactcgggcgtggcgctgccaggatactggatg ctgtttgtgatgaatagcgcgggcgtcccgagcgtagcgagcacgatccgtgtga cccaggccgcagcttgataa 176 GOh2071 MGSSHHHHHHSSGLVPRGSHMGTASAPIGSAIPRNNWAVTCDSAQSGNECNKAID GNKDTFWHTFYGANGDPKPPHTYTIDMKTTQNVNGLSVLPRQDGNQNGWIGRHEV YLSSDGDNWGSPVASGSWFADSTTKYSNFETRPARYVRLVAVTEANGQPWTSIAE INVFQASSYTAPQPGLGRWGPTIDLPIVPAAAAIEPTSGRVLMWSSYRNDAAEGS PGGITLTSSWDPSTGIVSDRTVTVTKHDMFCPGISMDGNGQIVVTGGWDAKKTSL YDSSSDSWIPGPDMQVARGYQSSATMSDGRVFTIGGSFSGGVFEKNGEVYSPSSK TWTSLPNAKVNPMLTADKQGLYMSDNHAWLFGWKKGSVFQAGPSTAMNWYYTSGS GDVKSAGKRQSNRGVAPDAMCGNAVMYDAVKGKILTFGGSPDYTDSDATTNAHII TLGEPGTSPNTVFASNGLYFARTFHTSVVLPDGSTFITGGQRRGIPFEDSTPVFT PEIYVPEQDTFYKQNPNSIVRAYHSISLLLPDGRVFNGGGGLCGDCTTNHFDAQI FTPNYLYDSNGNLATRPKITRTSTQSVKVGGRITISTDSSITKASLIRYGTATHT VNTDQRRIPLTLTNNGGNSYSFQVPSDSGVALPGYWMLFVMNSAGVPSVASTIRV TQAAA 177 GOh2072 atgggcagcagccatcatcatcatcatcacagcagcggcctggtgccgcgcggca gccatatgggtaccgcctctgcccctatcggctcagccatcccgcgcaataactg ggccgtaacgtgcgacagcgcgcagagcggcaacgagtgcaataaagccatcgac ggcaataaagacaccttctggcacacgttttatggcgcaaatggcgacccgaagc caccgcatacctataccattgacatgaaaaccacccagaatgtgaacgggctgtc cgtgctgccgcgccaggacggcaatcagaacggatggatcggccgtcacgaggta tatttaagccgtgacggcaccaactggggatccccggtcgcgtcgggcagctggt tcgccgacagcaccaccaagtattccaattttgaaacccgtcctgcacgctacgt gcgcttagtggccgtgacagaggcgaacggccagccatggacctcaatcgccgaa atcaatgtattccaagccagctcctataccgcgccgcagccaggacttgggcgtt ggggcccgaccatcgacctgcctatcgtacccgcagccgcggcgattgaaccaac gtcaggccgcgtactgatgtggagcagctaccgtaacgacgcggcggaaggcagc ccgggcggcatcactctgacgtcgagttgggatccatccacgggcatcgtctccg accgcaccgtgaccgtcacgaaacacgacatgttttgcccggggatcagcatgga cggcaacggccagatcgtcgtcacgggcggctgggacgccaagaagacgagcctc tatgacagtagcagcgacagttggatcccggggccggacatgcaggtggcacgcg ggtaccagtccagcgcgaccatgtcagacggccgtgtctttacaatcggcggctc atttagtggcggagtgtttgagaagaatggcgaagtctatagcccctcatccaaa acgtggacgtcacttccgaacgcgaaggtgaatcccatgttaaccgccgacaaac agggcctgtacatgagcgacaaccatgcgtggctgttcggctggaagaaggggag cgtctttcaggcgggcccgtcgaccgcaatgaattggtattacacgtcaggaagc ggggacgtgaaatcagccggcaagcgccagtcgaaccgcggcgtggcgccggacg caatgtgcggcaatgccgtgatgtatgacgcggtcaaaggcaagatcctgacatt tggcgggagtccggactacaccgacagtgacgcgacaaccaatgcccacattatt acccttggggagccggggacgagcccgaacacggtcttcgcgtccaatggcctct atttcgcgcgtacctttcatacgtcggtggtcctgccggacggatcaacctttat caccggcggacagcgccgtggcatccccttcgaagactcgacccccgtctttaca ccggagatttatgtgccggaacaggacacgttttataaacagaatccgaactcga ttgtacgcgcgtatcactccatcagccttcttctcccggacggacgtgtctttaa tggcggaggaggactgtgcggggactgcacgaccaatcattttgacgcgcagatc tttaccccgaattatctgtatgattcaaatgggaatctcgcgacccgtccgaaaa ttacccgtacatcaacccagtccgtcaaagtgggcggccgcattacgatcagtac cgacagcagcattaccaaagcgtcactgattcgttacggcaccgcaacccataca gtcaacacggaccagcgccgtattccgttaaccctgaccaataacggtggcaatt cgtatagcttccaggtaccgtcggactcgggcgtggcgctgccaggatactggat gctgtttgtgatgaatagcgcgggcgtcccgagcgtagcgagcacgatccgtgtg acccaggccgcagcttgataa 178 GOh2072 MGSSHHHHHHSSGLVPRGSHMGTASAPIGSAIPRNNWAVTCDSAQSGNECNKAID GNKDTFWHTFYGANGDPKPPHTYTIDMKTTQNVNGLSVLPRQDGNQNGWIGRHEV YLSRDGTNWGSPVASGSWFADSTTKYSNFETRPARYVRLVAVTEANGQPWTSIAE INVFQASSYTAPQPGLGRWGPTIDLPIVPAAAAIEPTSGRVLMWSSYRNDAAEGS PGGITLTSSWDPSTGIVSDRTVTVTKHDMFCPGISMDGNGQIVVTGGWDAKKTSL YDSSSDSWIPGPDMQVARGYQSSATMSDGRVFTIGGSFSGGVFEKNGEVYSPSSK TWTSLPNAKVNPMLTADKQGLYMSDNHAWLFGWKKGSVFQAGPSTAMNWYYTSGS GDVKSAGKRQSNRGVAPDAMCGNAVMYDAVKGKILTFGGSPDYTDSDATTNAHII TLGEPGTSPNTVFASNGLYFARTFHTSVVLPDGSTFITGGQRRGIPFEDSTPVFT PEIYVPEQDTFYKQNPNSIVRAYHSISLLLPDGRVFNGGGGLCGDCTTNHFDAQI FTPNYLYDSNGNLATRPKITRTSTQSVKVGGRITISTDSSITKASLIRYGTATHT VNTDQRRIPLTLTNNGGNSYSFQVPSDSGVALPGYWMLFVMNSAGVPSVASTIRV TQAAA 179 GOh2073 atgggcagcagccatcatcatcatcatcacagcagcggcctggtgccgcgcggca gccatatgggtaccgcctctgcccctatcggctcagccatcccgcgcaataactg ggccgtaacgtgcgacagcgcgcagagcggcaacgagtgcaataaagccatcgac ggcaataaagacaccttctggcacacgttttatggcgcaaatggcgacccgaagc caccgcatacctataccattgacatgaaaaccacccagaatgtgaacgggctgtc cgtgctgccgcgccaggacggcaatcagaacggatggatcggccgtcacgaggta tatttaagctccgacggcaccaactggggatccccggtcgcgtcgggcagctggt tcgccgacagcaccaccaagtattccaattttgaaacccgtcctgcacgctacgt gcgcttagtggccgtgacagaggcgaacggccagccatggacctcaatcgccgaa atcaatgtattccaagccagctcctataccgcgccgcagccaggacttgggcgtt ggggcccgaccatcgacctgcctatcgtacccgcagccgcggcgattgaaccaac gtcaggccgcgtactgatgtggagcagctaccgtaacgacgcggcggaaggcagc ccgggcggcatcactctgacgtcgagttgggatccatccacgggcatcgtctccg accgcaccgtgaccgtcacgaaacacgacatgttttgcccggggatcagcatgga cggcaacggccagatcgtcgtcacgggcggctgggacgccaagaagacgagcctc tatgacagtagcagcgacagttggatcccggggccggacatgcaggtggcacgcg ggtaccagtccagcgcgaccatgtcagacggccgtgtctttacaatcggcggctc atttagtggcggagtgtttgagaagaatggcgaagtctatagcccctcatccaaa acgtggacgtcacttccgaacgcgaaggtgaatcccatgttaaccgccgacaaac agggcctgtacatgagcgacaaccatgcgtggctgttcggctggaagaaggggag cgtctttcaggcgggcccgtcgaccgcaatgaattggtattacacgtcaggaagc ggggacgtgaaatcagccggcaagcgccagtcgaaccgcggcgtggcgccggacg caatgtgcggcaatgccgtgatgtatgacgcggtcaaaggcaagatcctgacatt tggcgggagtccggactacaccgacagtgacgcgacaaccaatgcccacattatt acccttggggagccggggacgagcccgaacacggtcttcgcgtccaatggcctct atttcgcgcgtacctttcatacgtcggtggtcctgccggacggatcaacctttat caccggcggacagcgccgtggcatccccttcgaagactcgacccccgtctttaca ccggagatttatgtgccggaacaggacacgttttataaacagaatccgaactcga ttgtacgcgcgtatcactccatcagccttcttctcccggacggacgtgtctttaa tggcggaggaggactgtgcggggactgcacgaccaatcattttgacgcgcagatc tttaccccgaattatctgtatgatccgaatgggaatctcgcgacccgtccgaaaa ttacccgtacatcaacccagtccgtcaaagtgggcggccgcattacgatcagtac cgacagcagcattaccaaagcgtcactgattcgttacggcaccgcaacccataca gtcaacacggaccagcgccgtattccgttaaccctgaccaataacggtggcaatt cgtatagcttccaggtaccgtcggactcgggcgtggcgctgccaggatactggat gctgtttgtgatgaatagcgcgggcgtcccgagcgtagcgagcacgatccgtgtg acccaggccgcagcttgataa 180 GOh2073 MGSSHHHHHHSSGLVPRGSHMGTASAPIGSAIPRNNWAVTCDSAQSGNECNKAID GNKDTFWHTFYGANGDPKPPHTYTIDMKTTQNVNGLSVLPRQDGNQNGWIGRHEV YLSSDGTNWGSPVASGSWFADSTTKYSNFETRPARYVRLVAVTEANGQPWTSIAE INVFQASSYTAPQPGLGRWGPTIDLPIVPAAAAIEPTSGRVLMWSSYRNDAAEGS PGGITLTSSWDPSTGIVSDRTVTVTKHDMFCPGISMDGNGQIVVTGGWDAKKTSL YDSSSDSWIPGPDMQVARGYQSSATMSDGRVFTIGGSFSGGVFEKNGEVYSPSSK TWTSLPNAKVNPMLTADKQGLYMSDNHAWLFGWKKGSVFQAGPSTAMNWYYTSGS GDVKSAGKRQSNRGVAPDAMCGNAVMYDAVKGKILTFGGSPDYTDSDATTNAHII TLGEPGTSPNTVFASNGLYFARTFHTSVVLPDGSTFITGGQRRGIPFEDSTPVFT PEIYVPEQDTFYKQNPNSIVRAYHSISLLLPDGRVFNGGGGLCGDCTTNHFDAQI FTPNYLYDPNGNLATRPKITRTSTQSVKVGGRITISTDSSITKASLIRYGTATHT VNTDQRRIPLTLTNNGGNSYSFQVPSDSGVALPGYWMLFVMNSAGVPSVASTIRV TQAAA 181 GOh2074 atgggcagcagccatcatcatcatcatcacagcagcggcctggtgccgcgcggca gccatatgggtaccgcctctgcccctatcggctcagccatcccgcgcaataactg ggccgtaacgtgcgacagcgcgcagagcggcaacgagtgcaataaagccatcgac ggcaataaagacaccttctggcacacgttttatggcgcaaatggcgacccgaagc caccgcatacctataccattgacatgaaaaccacccagaatgtgaacgggctgtc cgtgctgccgcgccaggacggcaatcagaacggatggatcggccgtcacgaggta tatttaagcaatgacggcaccaactggggatccccggtcgcgtcgggcagctggt tcgccgacagcaccaccaagtattccaattttgaaacccgtcctgcacgctacgt gcgcttagtggccgtgacagaggcgaacggccagccatggacctcaatcgccgaa atcaatgtattccaagccagctcctataccgcgccgcagccaggacttgggcgtt ggggcccgaccatcgacctgcctatcgtacccgcagccgcggcgattgaaccaac gtcaggccgcgtactgatgtggagcagctaccgtaacgacgcggcggaaggcagc ccgggggcatcactctgacgtcgagttgggatccatccacgggcatcgtctccga ccgcaccgtgaccgtcacgaaacacgacatgttttgcccggggatcagcatggac ggcaacggccagatcgtcgtcacgggcggctgggacgccaagaagacgagcctct atgacagtagcagcgacagttggatcccggggccggacatgcaggtggcacgcgg gtaccagtccagcgcgaccatgtcagacggccgtgtctttacaatcggcggctca tttagtggcggagtgtttgagaagaatggcgaagtctatagcccctcatccaaaa cgtggacgtcacttccgaacgcgaaggtgaatcccatgttaaccgccgacaaaca gggcctgtacatgagcgacaaccatgcgtggctgttcggctggaagaaggggagc gtctttcaggcgggcccgtcgaccgcaatgaattggtattacacgtcaggaagcg gggacgtgaaatcagccggcaagcgccagtcgaaccgcggcgtggcgccggacgc aatgtgcggcaatgccgtgatgtatgacgcggtcaaaggcaagatcctgacattt ggcgggagtccggactacaccgacagtgacgcgacaaccaatgcccacattatta cccttggggagccggggacgagcccgaacacggtcttcgcgtccaatggcctcta tttcgcgcgtacctttcatacgtcggtggtcctgccggacggatcaacctttatc accggcggacagcgccgtggcatccccttcgaagactcgacccccgtctttacac cggagatttatgtgccggaacaggacacgttttataaacagaatccgaactcgat tgtacgcgcgtatcactccatcagccttcttctcccggacggacgtgtctttaat ggcggaggaggactgtgcggggactgcacgaccaatcattttgacgcgcagatct ttaccccgaattatctgtatgattcaaatgggaatctcgcgacccgtccgaaaat tacccgtacatcaacccagtccgtcaaagtgggcggccgcattacgatcagtacc gacagcagcattaccaaagcgtcactgattcgttacggcaccgcaacccatacag tcaacacggaccagcgccgtattccgttaaccctgaccaataacggtggcaattc gtatagcttccaggtaccgtcggactcgggcgtggcgctgccaggatactggatg ctgtttgtgatgaatagcgcgggcgtcccgagcgtagcgagcacgatccgtgtga cccaggccgcagcttgataa 182 GOh2074 MGSSHHHHHHSSGLVPRGSHMGTASAPIGSAIPRNNWAVTCDSAQSGNECNKAID GNKDTFWHTFYGANGDPKPPHTYTIDMKTTQNVNGLSVLPRQDGNQNGWIGRHEV YLSNDGTNWGSPVASGSWFADSTTKYSNFETRPARYVRLVAVTEANGQPWTSIAE INVFQASSYTAPQPGLGRWGPTIDLPIVPAAAAIEPTSGRVLMWSSYRNDAAEGS PGGITLTSSWDPSTGIVSDRTVTVTKHDMFCPGISMDGNGQIVVTGGWDAKKTSL YDSSSDSWIPGPDMQVARGYQSSATMSDGRVFTIGGSFSGGVFEKNGEVYSPSSK TWTSLPNAKVNPMLTADKQGLYMSDNHAWLFGWKKGSVFQAGPSTAMNWYYTSGS GDVKSAGKRQSNRGVAPDAMCGNAVMYDAVKGKILTFGGSPDYTDSDATTNAHII TLGEPGTSPNTVFASNGLYFARTFHTSVVLPDGSTFITGGQRRGIPFEDSTPVFT PEIYVPEQDTFYKQNPNSIVRAYHSISLLLPDGRVFNGGGGLCGDCTTNHFDAQI FTPNYLYDSNGNLATRPKITRTSTQSVKVGGRITISTDSSITKASLIRYGTATHT VNTDQRRIPLTLTNNGGNSYSFQVPSDSGVALPGYWMLFVMNSAGVPSVASTIRV TQAAA 183 GOh2075 atgggcagcagccatcatcatcatcatcacagcagcggcctggtgccgcgcggca gccatatgggtaccgcctctgcccctatcggctcagccatcccgcgcaataactg ggccgtaacgtgcgacagcgcgcagagcggcaacgagtgcaataaagccatcgac ggcaataaagacaccttctggcacacgttttatggcgcaaatggcgacccgaagc caccgcatacctataccattgacatgaaaaccacccagaatgtgaacgggctgtc cgtgctgccgcgccaggacggcaatcagaacggatggatcggccgtcacgaggta tatttaagctccgacggcaccaactggggatccccggtcgcgtcgggcagctggt tcgccgacagcaccaccaagtattccaattttgaaacccgtcctgcacgctacgt gcgcttagtggccgtgacagaggcgaacggccagccatggacctcaatcgccgaa atcaatgtattccaagccagctcctataccgcgccgcagccaggacttgggcgtt ggggcccgaccatcgacctgcctatcgtacccgcagccgcggcgattgaaccaac gtcaggccgcgtactgatgtggagcagctaccgtaacgacgcggcggaaggcagc ccgggcggcatcactctgacgtcgagttgggatccatccacgggcatcgtctccg accgcaccgtgaccgtcacgaaacacgacatgttttgcccggggatcagcatgga cggcaacggccagatcgtcgtcactggcggctgggacgccaagaagacgagcctc tatgacagtagcagcgacagttggatcccggggccggacatgcaggtggcacgcg ggtaccagtccagcgcgaccatgtcagacggccgtgtctttacaatcggcggctc atttagtggcggagtgtttgagaagaatggcgaagtctatagcccctcatccaaa acgtggacgtcacttccgaacgcgaaggtgaatcccatgttaaccgccgacaaac agggcctgtacatgagcgacaaccatgcgtggctgttcggctggaagaaggggag cgtctttcaggcgggcccgtcgaccgcaatgaattggtattacacgtcaggaagc ggggacgtgaaatcagccggcaagcgccagtcgaaccgcggcgtggcgccggacg caatgtgcggcaatgccgtgatgtatgacgcggtcaaaggcaagatcctgacatt tgggggagtccggactacaccgacagtgacgcgacaaccaatgcccacattatta cccttggggagccggggacgagcccgaacacggtcttcgcgtccaatggcctcta tttcgcgcgtacctttcatacgtcggtggtcctgccggacggatcaacctttatc accggcggacagcgccgtggcatccccttcgaagactcgacccccgtctttacac cggagatttatgtgccggaacaggacacgttttataaacagaatccgaactcgat tgtacgcgcgtatcactccatcagccttcttctcccggacggacgtgtctttaat ggcggaggaggactgtgcggggactgcacgaccaatcattttgacgcgcagatct ttaccccgaattatctgtatgattcaaatgggaatctcgcgacccgtccgaaaat tacccgtacatcaacccagtccgtcaaagtgggcggccgcattacgatcagtacc gacagcagcattaccaaagcgtcactgattcgttacggcaccgcaacccatacag tcaacacggaccagcgccgtattccgttaaccctgaccaataacggtggcaattc gtatagcttccaggtaccgtcggactcgggcgtggcgctgccaggatactggatg ctgtttgtgatgaatagcgcgggcgtcccgagcgtagcgagcacgatccgtgtga ccccggccgcagcttgataa 184 GOh2075 MGSSHHHHHHSSGLVPRGSHMGTASAPIGSAIPRNNWAVTCDSAQSGNECNKAID GNKDTFWHTFYGANGDPKPPHTYTIDMKTTQNVNGLSVLPRQDGNQNGWIGRHEV YLSSDGTNWGSPVASGSWFADSTTKYSNFETRPARYVRLVAVTEANGQPWTSIAE INVFQASSYTAPQPGLGRWGPTIDLPIVPAAAAIEPTSGRVLMWSSYRNDAAEGS PGGITLTSSWDPSTGIVSDRTVTVTKHDMFCPGISMDGNGQIVVTGGWDAKKTSL YDSSSDSWIPGPDMQVARGYQSSATMSDGRVFTIGGSFSGGVFEKNGEVYSPSSK TWTSLPNAKVNPMLTADKQGLYMSDNHAWLFGWKKGSVFQAGPSTAMNWYYTSGS GDVKSAGKRQSNRGVAPDAMCGNAVMYDAVKGKILTFGGSPDYTDSDATTNAHII TLGEPGTSPNTVFASNGLYFARTFHTSVVLPDGSTFITGGQRRGIPFEDSTPVFT PEIYVPEQDTFYKQNPNSIVRAYHSISLLLPDGRVFNGGGGLCGDCTTNHFDAQI FTPNYLYDSNGNLATRPKITRTSTQSVKVGGRITISTDSSITKASLIRYGTATHT VNTDQRRIPLTLTNNGGNSYSFQVPSDSGVALPGYWMLFVMNSAGVPSVASTIRV TPAAA 185 GOh2076 atgggcagcagccatcatcatcatcatcacagcagcggcctggtgccgcgcggca gccatatgggtaccgcctctgcccctatcggctcagccatcccgcgcaataactg ggccgtaacgtgcgacagcgcgcagagcggcaacgagtgcaataaagccatcgac ggcaataaagacaccttctggcacacgttttatggcgcaaatggcgacccgaagc caccgcatacctataccattgacatgaaaaccacccagaatgtgaacgggctgtc cgtgctgccgcgccaggacggcaatcagaacggatggatcggccgtcacgaggta tatttaagctccgacggcaccaactggggatccccggtcgcgtcgggcagctggt tcgccgacagcaccaccaagtattccaattttgaaacccgtcctgcacgctacgt gcgcttagtggccgtgacagaggcgaacggccagccatggacctcaatcgccgaa atcaatgtattccaagccagccgttataccgcgccgcagccaggacttgggcgtt ggggcccgaccatcgacctgcctatcgtacccgcagccgcggcgattgaaccaac gtcaggccgcgtactgatgtggagcagctaccgtaacgacgcggcggaaggcagc ccgggcggcatcactctgacgtcgagttgggatccatccacgggcatcgtctccg accgcaccgtgaccgtcacgaaacacgacatgttttgcccggggatcagcatgga cggcaacggccagatcgtcgtcacgggcggctgggacgccaagaagacgagcctc tatgacagtagcagcgacagttggatcccggggccggacatgcaggtggcacgcg ggtaccagtccagcgcgaccatgtcagacggccgtgtctttacaatcggcggctc atttagtggcggagtgtttgagaagaatggcgaagtctatagcccctcatccaaa acgtggacgtcacttccgaacgcgaaggtgaatcccatgttaaccgccgacaaac agggcctgtacatgagcgacaaccatgcgtggctgttcggctggaagaaggggag cgtctttcaggcgggcccgtcgaccgcaatgaattggtattacacgtcaggaagc ggggacgtgaaatcagccggcaagcgccagtcgaaccgcggcgtggcgccggacg caatgtgcggcaatgccgtgatgtatgacgcggtcaaaggcaagatcctgacatt tggcgggagtccggactacaccgacagtgacgcgacaaccaatgcccacattatt acccttggggagccggggacgagcccgaacacggtcttcgcgtccaatggcctct atttcgcgcgtacctttcatacgtcggtggtcctgccggacggatcaacctttat caccggggacagcgccgtggcatccccttcgaagactcgacccccgtctttacac cggagatttatgtgccggaacaggacacgttttataaacagaatccgaactcgat tgtacgcgcgtatcactccatcagccttcttctcccggacggacgtgtctttaat ggcggaggaggactgtgcggggactgcacgaccaatcattttgacgcgcagatct ttaccccgaattatctgtatgattcaaatgggaatctcgcgacccgtccgaaaat tacccgtacatcaacccagtccgtcaaagtgggggccgcattacgatcagtaccg acagcagcattaccaaagcgtcactgattcgttacggcaccgcaacccatacagt caacacggaccagcgccgtattccgttaaccctgaccaataacggtggcaattcg tatagcttccaggtaccgtcggactcgggcgtggcgctgccaggatactggatgc tgtttgtgatgaatagcgcgggcgtcccgagcgtagcgagcacgatccgtgtgac ccaggccgcagcttgataa 186 GOh2076 MGSSHHHHHHSSGLVPRGSHMGTASAPIGSAIPRNNWAVTCDSAQSGNECNKAID GNKDTFWHTFYGANGDPKPPHTYTIDMKTTQNVNGLSVLPRQDGNQNGWIGRHEV YLSSDGTNWGSPVASGSWFADSTTKYSNFETRPARYVRLVAVTEANGQPWTSIAE INVFQASRYTAPQPGLGRWGPTIDLPIVPAAAAIEPTSGRVLMWSSYRNDAAEGS PGGITLTSSWDPSTGIVSDRTVTVTKHDMFCPGISMDGNGQIVVTGGWDAKKTSL YDSSSDSWIPGPDMQVARGYQSSATMSDGRVFTIGGSFSGGVFEKNGEVYSPSSK TWTSLPNAKVNPMLTADKQGLYMSDNHAWLFGWKKGSVFQAGPSTAMNWYYTSGS GDVKSAGKRQSNRGVAPDAMCGNAVMYDAVKGKILTFGGSPDYTDSDATTNAHII TLGEPGTSPNTVFASNGLYFARTFHTSVVLPDGSTFITGGQRRGIPFEDSTPVFT PEIYVPEQDTFYKQNPNSIVRAYHSISLLLPDGRVFNGGGGLCGDCTTNHFDAQI FTPNYLYDSNGNLATRPKITRTSTQSVKVGGRITISTDSSITKASLIRYGTATHT VNTDQRRIPLTLTNNGGNSYSFQVPSDSGVALPGYWMLFVMNSAGVPSVASTIRV TQAAA 187 GOh2077 atgggcagcagccatcatcatcatcatcacagcagcggcctggtgccgcgcggca gccatatgggtaccgcctctgcccctatcggctcagccatcccgcgcaataactg ggccgtaacgtgcgacagcgcgcagagcggcaacgagtgcaataaagccatcgac ggcaataaagacaccttctggcacacgttttatggcgcaaatggcgacccgaagc caccgcatacctataccattgacatgaaaaccacccagaatgtgaacgggctgtc cgtgctgccgcgccaggacggcaatcagaacggatggatcggccgtcacgaggta tatttaagctccgacggcaccaactggggatccccggtcgcgtcgggcagctggt tcgccgacagcaccaccaagtattccaattttgaaacccgtcctgcacgctacgt gcgcttagtggccgtgacagaggcgaacggccagccatggacctcaatcgccgaa atcaatgtattccaagccagctcctataccgcgccgcagccaggacttgggcgtt ggggcccgaccatcgacctgcctatcgtacccgcagccgcggcgattgaaccaac gtcaggccgcgtactgatgtggagcagctaccgtaacgacgcggcggaaggcagc ccgggcggcatcactctgacgtcgagttgggatccatccacgggcatcgtctccc cgcgcaccgtgaccgtcacgaaacacgacatgttttgcccggggatcagcatgga cggcaacggccagatcgtcgtcacgggcggctgggacgccaagaagacgagcctc tatgacagtagcagcgacagttggatcccggggccggacatgcaggtggcacgcg ggtaccagtccagcgcgaccatgtcagacggccgtgtctttacaatcggcggctc atttagtggcggagtgtttgagaagaatggcgaagtctatagcccctcatccaaa acgtggacgtcacttccgaacgcgaaggtgaatcccatgttaaccgccgacaaac agggcctgtacatgagcgacaaccatgcgtggctgttcggctggaagaaggggag cgtctttcaggcgggcccgtcgaccgcaatgaattggtattacacgtcaggaagc ggggacgtgaaatcagccggcaagcgccagtcgaaccgcggcgtggcgccggacg caatgtgcggcaatgccgtgatgtatgacgcggtcaaaggcaagatcctgacatt tggcgggagtccggactacaccgacagtgacgcgacaaccaatgcccacattatt acccttggggagccggggacgagcccgaacacggtcttcgcgtccaatggcctct atttcgcgcgtacctttcatacgtcggtggtcctgccggacggatcaacctttat caccggcggacagcgccgtggcatccccttcgaagactcgacccccgtctttaca ccggagatttatgtgccggaacaggacacgttttataaacagaatccgaactcga ttgtacgcgcgtatcactccatcagccttcttctcccggacggacgtgtctttaa tggcggaggaggactgtgcggggactgcacgaccaatcattttgacgcgcagatc tttaccccgaattatctgtatgattcaaatgggaatctcgcgacccgtccgaaaa ttacccgtacatcaacccagtccgtcaaagtgggggccgcattacgatcagtacc gacagcagcattaccaaagcgtcactgattcgttacggcaccgcaacccatacag tcaacacggaccagcgccgtattccgttaaccctgaccaataacggtggcaattc gtatagcttccaggtaccgtcggactcgggcgtggcgctgccaggatactggatg ctgtttgtgatgaatagcgcgggcgtcccgagcgtagcgagcacgatccgtgtga cccaggccgcagcttgataa 188 GOh2077 MGSSHHHHHHSSGLVPRGSHMGTASAPIGSAIPRNNWAVTCDSAQSGNECNKAID GNKDTFWHTFYGANGDPKPPHTYTIDMKTTQNVNGLSVLPRQDGNQNGWIGRHEV YLSSDGTNWGSPVASGSWFADSTTKYSNFETRPARYVRLVAVTEANGQPWTSIAE INVFQASSYTAPQPGLGRWGPTIDLPIVPAAAAIEPTSGRVLMWSSYRNDAAEGS PGGITLTSSWDPSTGIVSPRTVTVTKHDMFCPGISMDGNGQIVVTGGWDAKKTSL YDSSSDSWIPGPDMQVARGYQSSATMSDGRVFTIGGSFSGGVFEKNGEVYSPSSK TWTSLPNAKVNPMLTADKQGLYMSDNHAWLFGWKKGSVFQAGPSTAMNWYYTSGS GDVKSAGKRQSNRGVAPDAMCGNAVMYDAVKGKILTFGGSPDYTDSDATTNAHII TLGEPGTSPNTVFASNGLYFARTFHTSVVLPDGSTFITGGQRRGIPFEDSTPVFT PEIYVPEQDTFYKQNPNSIVRAYHSISLLLPDGRVFNGGGGLCGDCTTNHFDAQI FTPNYLYDSNGNLATRPKITRTSTQSVKVGGRITISTDSSITKASLIRYGTATHT VNTDQRRIPLTLTNNGGNSYSFQVPSDSGVALPGYWMLFVMNSAGVPSVASTIRV TQAAA 189 GOh2078 atgggcagcagccatcatcatcatcatcacagcagcggcctggtgccgcgcggca gccatatgggtaccgcctctgcccctatcggctcagccatcccgcgcaataactg ggccgtaacgtgcgacagcgcgcagagcggcaacgagtgcaataaagccatcgac ggcaataaagacaccttctggcacacgttttatggcgcaaatggcgacccgaagc caccgcatacctataccattgacatgaaaaccacccagaatgtgaacgggctgtc cgtgctgccgcgccaggacggcaatcagaacggatggatcggccgtcacgaggta tatttaagctccgacggcaccaactggggatccccggtcgcgtcgggcagctggt tcgccgacagcaccaccaagtattccaattttgaaacccgtcctgcacgctacgt gcgcttagtggccgtgacagaggcgaacggccagccatggacctcaatcgccgaa atcaatgtattccaagccgaatcctataccgcgccgcagccaggacttgggcgtt ggggcccgaccatcgacctgcctatcgtacccgcagccgcggcgattgaaccaac gtcaggccgcgtactgatgtggagcagctaccgtaacgacgcggcggaaggcagc ccgggggcatcactctgacgtcgagttgggatccatccacgggcatcgtctccga ccgcaccgtgaccgtcacgaaacacgacatgttttgcccggggatcagcatggac ggcaacggccagatcgtcgtcacgggcggctgggacgccaagaagacgagcctct atgacagtagcagcgacagttggatcccggggccggacatgcaggtggcacgcgg gtaccagtccagcgcgaccatgtcagacggccgtgtctttacaatcggcggctca tttagtggcggagtgtttgagaagaatggcgaagtctatagcccctcatccaaaa cgtggacgtcacttccgaacgcgaaggtgaatcccatgttaaccgccgacaaaca gggcctgtacatgagcgacaaccatgcgtggctgttcggctggaagaaggggagc gtctttcaggcgggcccgtcgaccgcaatgaattggtattacacgtcaggaagcg gggacgtgaaatcagccggcaagcgccagtcgaaccgcggcgtggcgccggacgc aatgtgcggcaatgccgtgatgtatgacgcggtcaaaggcaagatcctgacattt ggcgggagtccggactacaccgacagtgacgcgacaaccaatgcccacattatta cccttggggagccggggacgagcccgaacacggtcttcgcgtccaatggcctcta tttcgcgcgtacctttcatacgtcggtggtcctgccggacggatcaacctttatc accggcggacagcgccgtggcatccccttcgaagactcgacccccgtctttacac cggagatttatgtgccggaacaggacacgttttataaacagaatccgaactcgat tgtacgcgcgtatcactccatcagccttcttctcccggacggacgtgtctttaat ggcggaggaggactgtgcggggactgcacgaccaatcattttgacgcgcagatct ttaccccgaattatctgtatgattcaaatgggaatctcgcgacccgtccgaaaat tacccgtacatcaacccagtccgtcaaagtgggcggccgcattacgatcagtacc gacagcagcattaccaaagcgtcactgattcgttacggcaccgcaacccatacag tcaacacggaccagcgccgtattccgttaaccctgaccaataacggtggcaattc gtatagcttccaggtaccgtcggactcgggcgtggcgctgccaggatactggatg ctgtttgtgatgaatagcgcgggcgtcccgagcgtagcgagcacgatccgtgtga cccaggccgcagcttgataa 190 GOh2078 MGSSHHHHHHSSGLVPRGSHMGTASAPIGSAIPRNNWAVTCDSAQSGNECNKAID GNKDTFWHTFYGANGDPKPPHTYTIDMKTTQNVNGLSVLPRQDGNQNGWIGRHEV YLSSDGTNWGSPVASGSWFADSTTKYSNFETRPARYVRLVAVTEANGQPWTSIAE INVFQAESYTAPQPGLGRWGPTIDLPIVPAAAAIEPTSGRVLMWSSYRNDAAEGS PGGITLTSSWDPSTGIVSDRTVTVTKHDMFCPGISMDGNGQIVVTGGWDAKKTSL YDSSSDSWIPGPDMQVARGYQSSATMSDGRVFTIGGSFSGGVFEKNGEVYSPSSK TWTSLPNAKVNPMLTADKQGLYMSDNHAWLFGWKKGSVFQAGPSTAMNWYYTSGS GDVKSAGKRQSNRGVAPDAMCGNAVMYDAVKGKILTFGGSPDYTDSDATTNAHII TLGEPGTSPNTVFASNGLYFARTFHTSVVLPDGSTFITGGQRRGIPFEDSTPVFT PEIYVPEQDTFYKQNPNSIVRAYHSISLLLPDGRVFNGGGGLCGDCTTNHFDAQI FTPNYLYDSNGNLATRPKITRTSTQSVKVGGRITISTDSSITKASLIRYGTATHT VNTDQRRIPLTLTNNGGNSYSFQVPSDSGVALPGYWMLFVMNSAGVPSVASTIRV TQAAA 191 GOh2079 atgggcagcagccatcatcatcatcatcacagcagcggcctggtgccgcgcggca gccatatgggtaccgcctctgcccctatcggctcagccatcccgcgcaataactg ggccgtaacgtgcgacagcgcgcagagcggcaacgagtgcaataaagccatcgac ggcaataaagacaccttctggcacacgttttatggcgcaaatggcgacccgaagc caccgcatacctataccattgacatgaaaaccacccagaatgtgaacgggctgtc cgtgctgccgcgccaggacggcaatcagaacggatggatcggccgtcacgaggta tatttaagctccgacggcaccaactggggatccccggtcgcgtcgggcagctggt tcgccgacagcaccaccaagtattccaattttgaaacccgtcctgcacgctacgt gcgcttagtggccgtgacagaggcgaacggccagccatggacctcaatcgccgaa atcaatgtattccaagccagctcctataccgcgccgcagccaggacttgggcgtt ggggcccgaccatcgacctgcctatcgtacccgcagccgcggcgattgaaccaac gtcaggccgcgtactgatgtggagcagctaccgtaacgacgcggcggaaggcagc ccgggcggcatcactctgacgtcgagttgggatccatccacgggcatcgtctccg accgcaccgtgaccgtcacgaaacacgacatgttttgcccggggatcagcatgga cggcaacggccagatcgtcgtcacgggcggctgggacgccaagaagacgagcctc tatgacagtagcagcgacagttggatcccggggccggacatgcaggtggcacgcg ggtaccagtccagcgcgaccatgtcagacggccgtgtctttacaatcggcggctc atttagtggcggagtgtttgagaagaatggcgaagtctatagcccctcatccaaa acgtggacgtcacttccgaacgcgaaggtgaatcccatgttaaccgccgacaaac agggcctgtacatgagcgacaaccatgcgtggctgttcggctggaagaaggggag cgtctttcaggcgggcccgtcgaccgcaatgaattggtattacacgtcaggaagc ggggacgtgaaatcagccggcaagcgccagtcgaaccgcggcgtggcgccggacg caatgtgcggcaatgccgtgatgtatgacgcggtcaaaggcaagatcctgacatt tgggggagtccggactacaccgacagtgacgcgacaaccaatgcccacattatta cccttggggagccggggacgagcccgaacacggtcttcgcgtccaatggcctcta tttcgcgcgtacctttcatacgtcggtggtcctgccggacggatcaacctttatc accggcggacagcgccgtggcatccccttcgaagactcgacccccgtctttacac cggagatttatgtgccggaacaggacacgttttataaacagaatccgaactcgat tgtacgcgcgtatcactccatcagccttcttctcccggacggacgtgtctttaat ggcggaggaggactgtgcggggactgcacgaccaatcattttgacgcgcagatct ttaccccgaattatctgtatgattcaaatgggaatctcgcgacccgtccgaaaat tacccgtacatcaacccagtccgtcaaagtgggcggccgcattacgatcagtacc gacagcagcattaccaaagcgtcactgattcgttacggcaccgcaacccatacag tcaacacggaccagcgccgtattccgttaaccctgaccaataacggtggcaattc gtatagcttccaggtaccgtcggactcgggcgtggcgctgccaggatactggatg ctgtttgtgatgaatagcgcgggcgtcccgagcgtagcgagcacgatccgtgtga ccgatgccgcagcttgataa 192 GOh2079 MGSSHHHHHHSSGLVPRGSHMGTASAPIGSAIPRNNWAVTCDSAQSGNECNKAID GNKDTFWHTFYGANGDPKPPHTYTIDMKTTQNVNGLSVLPRQDGNQNGWIGRHEV YLSSDGTNWGSPVASGSWFADSTTKYSNFETRPARYVRLVAVTEANGQPWTSIAE INVFQASSYTAPQPGLGRWGPTIDLPIVPAAAAIEPTSGRVLMWSSYRNDAAEGS PGGITLTSSWDPSTGIVSDRTVTVTKHDMFCPGISMDGNGQIVVTGGWDAKKTSL YDSSSDSWIPGPDMQVARGYQSSATMSDGRVFTIGGSFSGGVFEKNGEVYSPSSK TWTSLPNAKVNPMLTADKQGLYMSDNHAWLFGWKKGSVFQAGPSTAMNWYYTSGS GDVKSAGKRQSNRGVAPDAMCGNAVMYDAVKGKILTFGGSPDYTDSDATTNAHII TLGEPGTSPNTVFASNGLYFARTFHTSVVLPDGSTFITGGQRRGIPFEDSTPVFT PEIYVPEQDTFYKQNPNSIVRAYHSISLLLPDGRVFNGGGGLCGDCTTNHFDAQI FTPNYLYDSNGNLATRPKITRTSTQSVKVGGRITISTDSSITKASLIRYGTATHT VNTDQRRIPLTLTNNGGNSYSFQVPSDSGVALPGYWMLFVMNSAGVPSVASTIRV TDAAA 193 GOh2080 atgggcagcagccatcatcatcatcatcacagcagcggcctggtgccgcgcggca gccatatgggtaccgcctctgcccctatcggctcagccatcccgcgcaataactg ggccgtaacgtgcgacagcgcgcagagcggcaacgagtgcaataaagccatcgac ggcaataaagacaccttctggcacacgttttatggcgcaaatggcgacccgaagc caccgcatacctataccattgacatgaaaaccacccagaatgtgaacgggctgtc cgtgctgccgcgccaggacggcaatcagaacggatggatcggccgtcacgaggta tatttaagctccgacggcaccaactggggatccccggtcgcgtcgggcagctggt tcgccgacagcaccaccaagtattccaattttgaaacccgtcctgcacgctacgt gcgcttagtggccgtgacagaggcgaacggccagccatggacctcaatcgccgaa atcaatgtattccaagccagcaaatataccgcgccgcagccaggacttgggcgtt ggggcccgaccatcgacctgcctatcgtacccgcagccgcggcgattgaaccaac gtcaggccgcgtactgatgtggagcagctaccgtaacgacgcggcggaaggcagc ccgggcggcatcactctgacgtcgagttgggatccatccacgggcatcgtctccg accgcaccgtgaccgtcacgaaacacgacatgttttgcccggggatcagcatgga cggcaacggccagatcgtcgtcacgggcggctgggacgccaagaagacgagcctc tatgacagtagcagcgacagttggatcccggggccggacatgcaggtggcacgcg ggtaccagtccagcgcgaccatgtcagacggccgtgtctttacaatcggcggctc atttagtggcggagtgtttgagaagaatggcgaagtctatagcccctcatccaaa acgtggacgtcacttccgaacgcgaaggtgaatcccatgttaaccgccgacaaac agggcctgtacatgagcgacaaccatgcgtggctgttcggctggaagaaggggag cgtctttcaggcgggcccgtcgaccgcaatgaattggtattacacgtcaggaagc ggggacgtgaaatcagccggcaagcgccagtcgaaccgcggcgtggcgccggacg caatgtgcggcaatgccgtgatgtatgacgcggtcaaaggcaagatcctgacatt tgggggagtccggactacaccgacagtgacgcgacaaccaatgcccacattatta cccttggggagccggggacgagcccgaacacggtcttcgcgtccaatggcctcta tttcgcgcgtacctttcatacgtcggtggtcctgccggacggatcaacctttatc accggcggacagcgccgtggcatccccttcgaagactcgacccccgtctttacac cggagatttatgtgccggaacaggacacgttttataaacagaatccgaactcgat tgtacgcgcgtatcactccatcagccttcttctcccggacggacgtgtctttaat ggcggaggaggactgtgcggggactgcacgaccaatcattttgacgcgcagatct ttaccccgaattatctgtatgattcaaatgggaatctcgcgacccgtccgaaaat tacccgtacatcaacccagtccgtcaaagtgggcggccgcattacgatcagtacc gacagcagcattaccaaagcgtcactgattcgttacggcaccgcaacccatacag tcaacacggaccagcgccgtattccgttaaccctgaccaataacggtggcaattc gtatagcttccaggtaccgtcggactcgggcgtggcgctgccaggatactggatg ctgtttgtgatgaatagcgcgggcgtcccgagcgtagcgagcacgatccgtgtga cccaggccgcagcttgataa 194 GOh2080 MGSSHHHHHHSSGLVPRGSHMGTASAPIGSAIPRNNWAVTCDSAQSGNECNKAID GNKDTFWHTFYGANGDPKPPHTYTIDMKTTQNVNGLSVLPRQDGNQNGWIGRHEV YLSSDGTNWGSPVASGSWFADSTTKYSNFETRPARYVRLVAVTEANGQPWTSIAE INVFQASKYTAPQPGLGRWGPTIDLPIVPAAAAIEPTSGRVLMWSSYRNDAAEGS PGGITLTSSWDPSTGIVSDRTVTVTKHDMFCPGISMDGNGQIVVTGGWDAKKTSL YDSSSDSWIPGPDMQVARGYQSSATMSDGRVFTIGGSFSGGVFEKNGEVYSPSSK TWTSLPNAKVNPMLTADKQGLYMSDNHAWLFGWKKGSVFQAGPSTAMNWYYTSGS GDVKSAGKRQSNRGVAPDAMCGNAVMYDAVKGKILTFGGSPDYTDSDATTNAHII TLGEPGTSPNTVFASNGLYFARTFHTSVVLPDGSTFITGGQRRGIPFEDSTPVFT PEIYVPEQDTFYKQNPNSIVRAYHSISLLLPDGRVFNGGGGLCGDCTTNHFDAQI FTPNYLYDSNGNLATRPKITRTSTQSVKVGGRITISTDSSITKASLIRYGTATHT VNTDQRRIPLTLTNNGGNSYSFQVPSDSGVALPGYWMLFVMNSAGVPSVASTIRV TQAAA 195 GOh2081 atgggcagcagccatcatcatcatcatcacagcagcggcctggtgccgcgcggca gccatatgggtaccgcctctgcccctatcggctcagccatcccgcgcaataactg ggccgtaacgtgcgacagcgcgcagagcggcaacgagtgcaataaagccatcgac ggcaataaagacaccttctggcacacgttttatggcgcaaatggcgacccgaagc caccgcatacctataccattgacatgaaaaccacccagaatgtgaacgggctgtc cgtgctgccgcgccaggacggcaatcagaacggatggatcggccgtcacgaggta tatttaagctccgacggcaccaactggggatccccggtcgcgtcgggcagctggt tcgccgacagcaccaccaagtattccaattttgaaacccgtcctgcacgctacgt gcgcttagtggccgtgacagaggcgaacggccagccatggacctcaatcgccgaa atcaatgtattccaagccagctcctataccgcgccgcagccaggacttgggcgtt ggggcccgaccatcgacctgcctatcgtacccgttgccgcggcgattgaaccaac gtcaggccgcgtactgatgtggagcagctaccgtaacgacgcggcggaaggcagc ccgggcggcatcactctgacgtcgagttgggatccatccacgggcatcgtctccg accgcaccgtgaccgtcacgaaacacgacatgttttgcccggggatcagcatgga cggcaacggccagatcgtcgtcacgggcggctgggacgccaagaagacgagcctc tatgacagtagcagcgacagttggatcccggggccggacatgcaggtggcacgcg ggtaccagtccagcgcgaccatgtcagacggccgtgtctttacaatcggcggctc atttagtggcggagtgtttgagaagaatggcgaagtctatagcccctcatccaaa acgtggacgtcacttccgaacgcgaaggtgaatcccatgttaaccgccgacaaac agggcctgtacatgagcgacaaccatgcgtggctgttcggctggaagaaggggag cgtctttcaggcgggcccgtcgaccgcaatgaattggtattacacgtcaggaagc ggggacgtgaaatcagccggcaagcgccagtcgaaccgcggcgtggcgccggacg caatgtgcggcaatgccgtgatgtatgacgcggtcaaaggcaagatcctgacatt tggcgggagtccggactacaccgacagtgacgcgacaaccaatgcccacattatt acccttggggagccggggacgagcccgaacacggtcttcgcgtccaatggcctct atttcgcgcgtacctttcatacgtcggtggtcctgccggacggatcaacctttat caccggcggacagcgccgtggcatccccttcgaagactcgacccccgtctttaca ccggagatttatgtgccggaacaggacacgttttataaacagaatccgaactcga ttgtacgcgcgtatcactccatcagccttcttctcccggacggacgtgtctttaa tggcggaggaggactgtgcggggactgcacgaccaatcattttgacgcgcagatc tttaccccgaattatctgtatgattcaaatgggaatctcgcgacccgtccgaaaa ttacccgtacatcaacccagtccgtcaaagtgggcggccgcattacgatcagtac cgacagcagcattaccaaagcgtcactgattcgttacggcaccgcaacccataca gtcaacacggaccagcgccgtattccgttaaccctgaccaataacggtggcaatt cgtatagcttccaggtaccgtcggactcgggcgtggcgctgccaggatactggat gctgtttgtgatgaatagcgcgggcgtcccgagcgtagcgagcacgatccgtgtg acccaggccgcagcttgataa 196 GOh2081 MGSSHHHHHHSSGLVPRGSHMGTASAPIGSAIPRNNWAVTCDSAQSGNECNKAID GNKDTFWHTFYGANGDPKPPHTYTIDMKTTQNVNGLSVLPRQDGNQNGWIGRHEV YLSSDGTNWGSPVASGSWFADSTTKYSNFETRPARYVRLVAVTEANGQPWTSIAE INVFQASSYTAPQPGLGRWGPTIDLPIVPVAAAIEPTSGRVLMWSSYRNDAAEGS PGGITLTSSWDPSTGIVSDRTVTVTKHDMFCPGISMDGNGQIVVTGGWDAKKTSL YDSSSDSWIPGPDMQVARGYQSSATMSDGRVFTIGGSFSGGVFEKNGEVYSPSSK TWTSLPNAKVNPMLTADKQGLYMSDNHAWLFGWKKGSVFQAGPSTAMNWYYTSGS GDVKSAGKRQSNRGVAPDAMCGNAVMYDAVKGKILTFGGSPDYTDSDATTNAHII TLGEPGTSPNTVFASNGLYFARTFHTSVVLPDGSTFITGGQRRGIPFEDSTPVFT PEIYVPEQDTFYKQNPNSIVRAYHSISLLLPDGRVFNGGGGLCGDCTTNHFDAQI FTPNYLYDSNGNLATRPKITRTSTQSVKVGGRITISTDSSITKASLIRYGTATHT VNTDQRRIPLTLTNNGGNSYSFQVPSDSGVALPGYWMLFVMNSAGVPSVASTIRV TQAAA 197 GOh2082 atgggcagcagccatcatcatcatcatcacagcagcggcctggtgccgcgcggca gccatatgggtaccgcctctgcccctatcggctcagccatcccgcgcaataactg ggccgtaacgtgcgacagcgcgcagagcggcaacgagtgcaataaagccatcgac ggcaataaagacaccttctggcacacgttttatggcgcaaatggcgacccgaagc caccgcatacctataccattgacatgaaaaccacccagaatgtgaacgggctgtc cgtgctgccgcgccaggacggcaatcagaacggatggatcggccgtcacgaggta tatttaagctccgacggcaccaactggggatccccggtcgcgtcgggcagctggt tcgccgacagcaccaccaagtattccaattttgaaacccgtcctgcacgctacgt gcgcttagtggccgtgacagaggcgaacggccagccatggacctcaatcgccgaa atcaatgtattccaagccagctcctataccgcgccgcagccaggacttgggcgtt ggggcccgaccatcgacctgcctatcgtacccgcagccgcggcgattgaaccaac gtcaggccgcgtactgatgtggagcagctaccgtaacgacgcggcgtttggcagc ccgggcggcatcactctgacgtcgagttgggatccatccacgggcatcgtctccg accgcaccgtgaccgtcacgaaacacgacatgttttgcccggggatcagcatgga cggcaacggccagatcgtcgtcacgggcggctgggacgccaagaagacgagcctc tatgacagtagcagcgacagttggatcccggggccggacatgcaggtggcacgcg ggtaccagtccagcgcgaccatgtcagacggccgtgtctttacaatcggcggctc atttagtggcggagtgtttgagaagaatggcgaagtctatagcccctcatccaaa acgtggacgtcacttccgaacgcgaaggtgaatcccatgttaaccgccgacaaac agggcctgtacatgagcgacaaccatgcgtggctgttcggctggaagaaggggag cgtctttcaggcgggcccgtcgaccgcaatgaattggtattacacgtcaggaagc ggggacgtgaaatcagccggcaagcgccagtcgaaccgcggcgtggcgccggacg caatgtgcggcaatgccgtgatgtatgacgcggtcaaaggcaagatcctgacatt tggcgggagtccggactacaccgacagtgacgcgacaaccaatgcccacattatt acccttggggagccggggacgagcccgaacacggtcttcgcgtccaatggcctct atttcgcgcgtacctttcatacgtcggtggtcctgccggacggatcaacctttat caccggcggacagcgccgtggcatccccttcgaagactcgacccccgtctttaca ccggagatttatgtgccggaacaggacacgttttataaacagaatccgaactcga ttgtacgcgcgtatcactccatcagccttcttctcccggacggacgtgtctttaa tggcggaggaggactgtgcggggactgcacgaccaatcattttgacgcgcagatc tttaccccgaattatctgtatgattcaaatgggaatctcgcgacccgtccgaaaa ttacccgtacatcaacccagtccgtcaaagtgggcggccgcattacgatcagtac cgacagcagcattaccaaagcgtcactgattcgttacggcaccgcaacccataca gtcaacacggaccagcgccgtattccgttaaccctgaccaataacggtggcaatt cgtatagcttccaggtaccgtcggactcgggcgtggcgctgccaggatactggat gctgtttgtgatgaatagcgcgggcgtcccgagcgtagcgagcacgatccgtgtg acccaggccgcagcttgataa 198 GOh2082 MGSSHHHHHHSSGLVPRGSHMGTASAPIGSAIPRNNWAVTCDSAQSGNECNKAID GNKDTFWHTFYGANGDPKPPHTYTIDMKTTQNVNGLSVLPRQDGNQNGWIGRHEV YLSSDGTNWGSPVASGSWFADSTTKYSNFETRPARYVRLVAVTEANGQPWTSIAE INVFQASSYTAPQPGLGRWGPTIDLPIVPAAAAIEPTSGRVLMWSSYRNDAAFGS PGGITLTSSWDPSTGIVSDRTVTVTKHDMFCPGISMDGNGQIVVTGGWDAKKTSL YDSSSDSWIPGPDMQVARGYQSSATMSDGRVFTIGGSFSGGVFEKNGEVYSPSSK TWTSLPNAKVNPMLTADKQGLYMSDNHAWLFGWKKGSVFQAGPSTAMNWYYTSGS GDVKSAGKRQSNRGVAPDAMCGNAVMYDAVKGKILTFGGSPDYTDSDATTNAHII TLGEPGTSPNTVFASNGLYFARTFHTSVVLPDGSTFITGGQRRGIPFEDSTPVFT PEIYVPEQDTFYKQNPNSIVRAYHSISLLLPDGRVFNGGGGLCGDCTTNHFDAQI FTPNYLYDSNGNLATRPKITRTSTQSVKVGGRITISTDSSITKASLIRYGTATHT VNTDQRRIPLTLTNNGGNSYSFQVPSDSGVALPGYWMLFVMNSAGVPSVASTIRV TQAAA 199 GOh2083 atgggcagcagccatcatcatcatcatcacagcagcggcctggtgccgcgcggca gccatatgggtaccgcctctgcccctatcggctcagccatcccgcgcaataactg ggccgtaacgtgcgacagcgcgcagagcggcaacgagtgcaataaagccatcgac ggcaataaagacaccttctggcacacgttttatggcgcaaatggcgacccgaagc caccgcatacctataccattgacatgaaaaccacccagaatgtgaacgggctgtc cgtgctgccgcgccaggacggcaatcagaacggatggatcggccgtcacgaggta tatttaagctccgacggcaccaactggggatccccggtcgcgtcgggcagctggt tcgccgacagcaccaccaagtattccaattttgaaacccgtcctgcacgctacgt gcgcttagtggccgtgacagaggcgaacggccagccatggacctcaatcgccgaa atcaatgtattccaagccagctcctataccgcgccgcagccaggacttgggcgtt ggggcccgaccatcgacctgcctatcgtacccgcagccgcggcgattgaaccaac gtcaggccgcgtactgatgtggagcagctaccgtaacgacgcggcggaaggcagc ccgggcggcatcactcagacgtcgagttgggatccatccacgggcatcgtctccg accgcaccgtgaccgtcacgaaacacgacatgttttgcccggggatcagcatgga cggcaacggccagatcgtcgtcacgggcggctgggacgccaagaagacgagcctc tatgacagtagcagcgacagttggatcccggggccggacatgcaggtggcacgcg ggtaccagtccagcgcgaccatgtcagacggccgtgtctttacaatcggcggctc atttagtggcggagtgtttgagaagaatggcgaagtctatagcccctcatccaaa acgtggacgtcacttccgaacgcgaaggtgaatcccatgttaaccgccgacaaac agggcctgtacatgagcgacaaccatgcgtggctgttcggctggaagaaggggag cgtctttcaggcgggcccgtcgaccgcaatgaattggtattacacgtcaggaagc ggggacgtgaaatcagccggcaagcgccagtcgaaccgcggcgtggcgccggacg caatgtgcggcaatgccgtgatgtatgacgcggtcaaaggcaagatcctgacatt tggcgggagtccggactacaccgacagtgacgcgacaaccaatgcccacattatt acccttggggagccggggacgagcccgaacacggtcttcgcgtccaatggcctct atttcgcgcgtacctttcatacgtcggtggtcctgccggacggatcaacctttat caccggcggacagcgccgtggcatccccttcgaagactcgacccccgtctttaca ccggagatttatgtgccggaacaggacacgttttataaacagaatccgaactcga ttgtacgcgcgtatcactccatcagccttcttctcccggacggacgtgtctttaa tggcggaggaggactgtgcggggactgcacgaccaatcattttgacgcgcagatc tttaccccgaattatctgtatgattcaaatgggaatctcgcgacccgtccgaaaa ttacccgtacatcaacccagtccgtcaaagtgggcggccgcattacgatcagtac cgacagcagcattaccaaagcgtcactgattcgttacggcaccgcaacccataca gtcaacacggaccagcgccgtattccgttaaccctgaccaataacggtggcaatt cgtatagcttccaggtaccgtcggactcgggcgtggcgctgccaggatactggat gctgtttgtgatgaatagcgcgggcgtcccgagcgtagcgagcacgatccgtgtg acccaggccgcagcttgataa 200 GOh2083 MGSSHHHHHHSSGLVPRGSHMGTASAPIGSAIPRNNWAVTCDSAQSGNECNKAID GNKDTFWHTFYGANGDPKPPHTYTIDMKTTQNVNGLSVLPRQDGNQNGWIGRHEV YLSSDGTNWGSPVASGSWFADSTTKYSNFETRPARYVRLVAVTEANGQPWTSIAE INVFQASSYTAPQPGLGRWGPTIDLPIVPAAAAIEPTSGRVLMWSSYRNDAAEGS PGGITQTSSWDPSTGIVSDRTVTVTKHDMFCPGISMDGNGQIVVTGGWDAKKTSL YDSSSDSWIPGPDMQVARGYQSSATMSDGRVFTIGGSFSGGVFEKNGEVYSPSSK TWTSLPNAKVNPMLTADKQGLYMSDNHAWLFGWKKGSVFQAGPSTAMNWYYTSGS GDVKSAGKRQSNRGVAPDAMCGNAVMYDAVKGKILTFGGSPDYTDSDATTNAHII TLGEPGTSPNTVFASNGLYFARTFHTSVVLPDGSTFITGGQRRGIPFEDSTPVFT PEIYVPEQDTFYKQNPNSIVRAYHSISLLLPDGRVFNGGGGLCGDCTTNHFDAQI FTPNYLYDSNGNLATRPKITRTSTQSVKVGGRITISTDSSITKASLIRYGTATHT VNTDQRRIPLTLTNNGGNSYSFQVPSDSGVALPGYWMLFVMNSAGVPSVASTIRV TQAAA 201 GOh2084 atgggcagcagccatcatcatcatcatcacagcagcggcctggtgccgcgcggca gccatatgggtaccgcctctgcccctatcggctcagccatcccgcgcaataactg ggccgtaacgtgcgacagcgcgcagagcggcaacgagtgcaataaagccatcgac ggcaataaagacaccttctggcacacgttttatggcgcaaatggcgacccgaagc caccgcatacctataccattgacatgaaaaccacccagaatgtgaacgggctgtc cgtgctgccgcgccaggacggcaatcagaacggatggatcggccgtcacgaggta tatttaagctccgacggcaccaactggggatccccggtcgcgtcgggcagctggt tcgccgacagcaccaccaagtattccaattttgaaacccgtcctgcacgctacgt gcgcttagtggccgtgacagaggcgaacggccagccatggacctcaatcgccgaa atcaatgtattccaagccagctcctataccgcgccgcagccaggacttgggcgtt ggggcccgaccatcgacctgcctatcgtacccgcagccgcggcgattgaaccaac gtcaggccgcgtactgatgtggagcagctaccgtaacgacgcggcggaaggcagc ccgggcggctggactctgacgtcgagttgggatccatccacgggcatcgtctccg accgcaccgtgaccgtcacgaaacacgacatgttttgcccggggatcagcatgga cggcaacggccagatcgtcgtcacgggcggctgggacgccaagaagacgagcctc tatgacagtagcagcgacagttggatcccggggccggacatgcaggtggcacgcg ggtaccagtccagcgcgaccatgtcagacggccgtgtctttacaatcggcggctc atttagtggcggagtgtttgagaagaatggcgaagtctatagcccctcatccaaa acgtggacgtcacttccgaacgcgaaggtgaatcccatgttaaccgccgacaaac agggcctgtacatgagcgacaaccatgcgtggctgttcggctggaagaaggggag cgtctttcaggcgggcccgtcgaccgcaatgaattggtattacacgtcaggaagc ggggacgtgaaatcagccggcaagcgccagtcgaaccgcggcgtggcgccggacg caatgtgcggcaatgccgtgatgtatgacgcggtcaaaggcaagatcctgacatt tggcgggagtccggactacaccgacagtgacgcgacaaccaatgcccacattatt acccttggggagccggggacgagcccgaacacggtcttcgcgtccaatggcctct atttcgcgcgtacctttcatacgtcggtggtcctgccggacggatcaacctttat caccggcggacagcgccgtggcatccccttcgaagactcgacccccgtctttaca ccggagatttatgtgccggaacaggacacgttttataaacagaatccgaactcga ttgtacgcgcgtatcactccatcagccttcttctcccggacggacgtgtctttaa tggcggaggaggactgtgcggggactgcacgaccaatcattttgacgcgcagatc tttaccccgaattatctgtatgattcaaatgggaatctcgcgacccgtccgaaaa ttacccgtacatcaacccagtccgtcaaagtgggcggccgcattacgatcagtac cgacagcagcattaccaaagcgtcactgattcgttacggcaccgcaacccataca gtcaacacggaccagcgccgtattccgttaaccctgaccaataacggtggcaatt cgtatagcttccaggtaccgtcggactcgggcgtggcgctgccaggatactggat gctgtttgtgatgaatagcgcgggcgtcccgagcgtagcgagcacgatccgtgtg acccaggccgcagcttgataa 202 GOh2084 MGSSHHHHHHSSGLVPRGSHMGTASAPIGSAIPRNNWAVTCDSAQSGNECNKAID GNKDTFWHTFYGANGDPKPPHTYTIDMKTTQNVNGLSVLPRQDGNQNGWIGRHEV YLSSDGTNWGSPVASGSWFADSTTKYSNFETRPARYVRLVAVTEANGQPWTSIAE INVFQASSYTAPQPGLGRWGPTIDLPIVPAAAAIEPTSGRVLMWSSYRNDAAEGS PGGWTLTSSWDPSTGIVSDRTVTVTKHDMFCPGISMDGNGQIVVTGGWDAKKTSL YDSSSDSWIPGPDMQVARGYQSSATMSDGRVFTIGGSFSGGVFEKNGEVYSPSSK TWTSLPNAKVNPMLTADKQGLYMSDNHAWLFGWKKGSVFQAGPSTAMNWYYTSGS GDVKSAGKRQSNRGVAPDAMCGNAVMYDAVKGKILTFGGSPDYTDSDATTNAHII TLGEPGTSPNTVFASNGLYFARTFHTSVVLPDGSTFITGGQRRGIPFEDSTPVFT PEIYVPEQDTFYKQNPNSIVRAYHSISLLLPDGRVFNGGGGLCGDCTTNHFDAQI FTPNYLYDSNGNLATRPKITRTSTQSVKVGGRITISTDSSITKASLIRYGTATHT VNTDQRRIPLTLTNNGGNSYSFQVPSDSGVALPGYWMLFVMNSAGVPSVASTIRV TQAAA 203 GOh2085 atgggcagcagccatcatcatcatcatcacagcagcggcctggtgccgcgcggca gccatatgggtaccgcctctcgtcctatcggctcagccatcccgcgcaataactg ggccgtaacgtgcgacagcgcgcagagcggcaacgagtgcaataaagccatcgac ggcaataaagacaccttctggcacacgttttatggcgcaaatggcgacccgaagc caccgcatacctataccattgacatgaaaaccacccagaatgtgaacgggctgtc cgtgctgccgcgccaggacggcaatcagaacggatggatcggccgtcacgaggta tatttaagctccgacggcaccaactggggatccccggtcgcgtcgggcagctggt tcgccgacagcaccaccaagtattccaattttgaaacccgtcctgcacgctacgt gcgcttagtggccgtgacagaggcgaacggccagccatggacctcaatcgccgaa atcaatgtattccaagccagctcctataccgcgccgcagccaggacttgggcgtt ggggcccgaccatcgacctgcctatcgtacccgcagccgcggcgattgaaccaac gtcaggccgcgtactgatgtggagcagctaccgtaacgacgcggcggaaggcagc ccgggggcatcactctgacgtcgagttgggatccatccacgggcatcgtctccga ccgcaccgtgaccgtcacgaaacacgacatgttttgcccggggatcagcatggac ggcaacggccagatcgtcgtcacgggcggctgggacgccaagaagacgagcctct atgacagtagcagcgacagttggatcccggggccggacatgcaggtggcacgcgg gtaccagtccagcgcgaccatgtcagacggccgtgtctttacaatcggcggctca tttagtggcggagtgtttgagaagaatggcgaagtctatagcccctcatccaaaa cgtggacgtcacttccgaacgcgaaggtgaatcccatgttaaccgccgacaaaca gggcctgtacatgagcgacaaccatgcgtggctgttcggctggaagaaggggagc gtctttcaggcgggcccgtcgaccgcaatgaattggtattacacgtcaggaagcg gggacgtgaaatcagccggcaagcgccagtcgaaccgcggcgtggcgccggacgc aatgtgcggcaatgccgtgatgtatgacgcggtcaaaggcaagatcctgacattt ggcgggagtccggactacaccgacagtgacgcgacaaccaatgcccacattatta cccttggggagccggggacgagcccgaacacggtcttcgcgtccaatggcctcta tttcgcgcgtacctttcatacgtcggtggtcctgccggacggatcaacctttatc accggcggacagcgccgtggcatccccttcgaagactcgacccccgtctttacac cggagatttatgtgccggaacaggacacgttttataaacagaatccgaactcgat tgtacgcgcgtatcactccatcagccttcttctcccggacggacgtgtctttaat ggcggaggaggactgtgcggggactgcacgaccaatcattttgacgcgcagatct ttaccccgaattatctgtatgattcaaatgggaatctcgcgacccgtccgaaaat tacccgtacatcaacccagtccgtcaaagtgggcggccgcattacgatcagtacc gacagcagcattaccaaagcgtcactgattcgttacggcaccgcaacccatacag tcaacacggaccagcgccgtattccgttaaccctgaccaataacggtggcaattc gtatagcttccaggtaccgtcggactcgggcgtggcgctgccaggatactggatg ctgtttgtgatgaatagcgcgggcgtcccgagcgtagcgagcacgatccgtgtga cccaggccgcagcttgataa 204 GOh2085 MGSSHHHHHHSSGLVPRGSHMGTASRPIGSAIPRNNWAVTCDSAQSGNECNKAID GNKDTFWHTFYGANGDPKPPHTYTIDMKTTQNVNGLSVLPRQDGNQNGWIGRHEV YLSSDGTNWGSPVASGSWFADSTTKYSNFETRPARYVRLVAVTEANGQPWTSIAE INVFQASSYTAPQPGLGRWGPTIDLPIVPAAAAIEPTSGRVLMWSSYRNDAAEGS PGGITLTSSWDPSTGIVSDRTVTVTKHDMFCPGISMDGNGQIVVTGGWDAKKTSL YDSSSDSWIPGPDMQVARGYQSSATMSDGRVFTIGGSFSGGVFEKNGEVYSPSSK TWTSLPNAKVNPMLTADKQGLYMSDNHAWLFGWKKGSVFQAGPSTAMNWYYTSGS GDVKSAGKRQSNRGVAPDAMCGNAVMYDAVKGKILTFGGSPDYTDSDATTNAHII TLGEPGTSPNTVFASNGLYFARTFHTSVVLPDGSTFITGGQRRGIPFEDSTPVFT PEIYVPEQDTFYKQNPNSIVRAYHSISLLLPDGRVFNGGGGLCGDCTTNHFDAQI FTPNYLYDSNGNLATRPKITRTSTQSVKVGGRITISTDSSITKASLIRYGTATHT VNTDQRRIPLTLTNNGGNSYSFQVPSDSGVALPGYWMLFVMNSAGVPSVASTIRV TQAAA 205 GOh2086 atgggcagcagccatcatcatcatcatcacagcagcggcctggtgccgcgcggca gccatatgggtaccgcctctgccccttttggctcagccatcccgcgcaataactg ggccgtaacgtgcgacagcgcgcagagcggcaacgagtgcaataaagccatcgac ggcaataaagacaccttctggcacacgttttatggcgcaaatggcgacccgaagc caccgcatacctataccattgacatgaaaaccacccagaatgtgaacgggctgtc cgtgctgccgcgccaggacggcaatcagaacggatggatcggccgtcacgaggta tatttaagctccgacggcaccaactggggatccccggtcgcgtcgggcagctggt tcgccgacagcaccaccaagtattccaattttgaaacccgtcctgcacgctacgt gcgcttagtggccgtgacagaggcgaacggccagccatggacctcaatcgccgaa atcaatgtattccaagccagctcctataccgcgccgcagccaggacttgggcgtt ggggcccgaccatcgacctgcctatcgtacccgcagccgcggcgattgaaccaac gtcaggccgcgtactgatgtggagcagctaccgtaacgacgcggcggaaggcagc ccgggcggcatcactctgacgtcgagttgggatccatccacgggcatcgtctccg accgcaccgtgaccgtcacgaaacacgacatgttttgcccggggatcagcatgga cggcaacggccagatcgtcgtcacgggcggctgggacgccaagaagacgagcctc tatgacagtagcagcgacagttggatcccggggccggacatgcaggtggcacgcg ggtaccagtccagcgcgaccatgtcagacggccgtgtctttacaatcggcggctc atttagtggcggagtgtttgagaagaatggcgaagtctatagcccctcatccaaa acgtggacgtcacttccgaacgcgaaggtgaatcccatgttaaccgccgacaaac agggcctgtacatgagcgacaaccatgcgtggctgttcggctggaagaaggggag cgtctttcaggcgggcccgtcgaccgcaatgaattggtattacacgtcaggaagc ggggacgtgaaatcagccggcaagcgccagtcgaaccgcggcgtggcgccggacg caatgtgcggcaatgccgtgatgtatgacgcggtcaaaggcaagatcctgacatt tggcgggagtccggactacaccgacagtgacgcgacaaccaatgcccacattatt acccttggggagccggggacgagcccgaacacggtcttcgcgtccaatggcctct atttcgcgcgtacctttcatacgtcggtggtcctgccggacggatcaacctttat caccggcggacagcgccgtggcatccccttcgaagactcgacccccgtctttaca ccggagatttatgtgccggaacaggacacgttttataaacagaatccgaactcga ttgtacgcgcgtatcactccatcagccttcttctcccggacggacgtgtctttaa tggcggaggaggactgtgcggggactgcacgaccaatcattttgacgcgcagatc tttaccccgaattatctgtatgattcaaatgggaatctcgcgacccgtccgaaaa ttacccgtacatcaacccagtccgtcaaagtgggcggccgcattacgatcagtac cgacagcagcattaccaaagcgtcactgattcgttacggcaccgcaacccataca gtcaacacggaccagcgccgtattccgttaaccctgaccaataacggtggcaatt cgtatagcttccaggtaccgtcggactcgggcgtggcgctgccaggatactggat gctgtttgtgatgaatagcgcgggcgtcccgagcgtagcgagcacgatccgtgtg acccaggccgcagcttgataa 206 GOh2086 MGSSHHHHHHSSGLVPRGSHMGTASAPFGSAIPRNNWAVTCDSAQSGNECNKAID GNKDTFWHTFYGANGDPKPPHTYTIDMKTTQNVNGLSVLPRQDGNQNGWIGRHEV YLSSDGTNWGSPVASGSWFADSTTKYSNFETRPARYVRLVAVTEANGQPWTSIAE INVFQASSYTAPQPGLGRWGPTIDLPIVPAAAAIEPTSGRVLMWSSYRNDAAEGS PGGITLTSSWDPSTGIVSDRTVTVTKHDMFCPGISMDGNGQIVVTGGWDAKKTSL YDSSSDSWIPGPDMQVARGYQSSATMSDGRVFTIGGSFSGGVFEKNGEVYSPSSK TWTSLPNAKVNPMLTADKQGLYMSDNHAWLFGWKKGSVFQAGPSTAMNWYYTSGS GDVKSAGKRQSNRGVAPDAMCGNAVMYDAVKGKILTFGGSPDYTDSDATTNAHII TLGEPGTSPNTVFASNGLYFARTFHTSVVLPDGSTFITGGQRRGIPFEDSTPVFT PEIYVPEQDTFYKQNPNSIVRAYHSISLLLPDGRVFNGGGGLCGDCTTNHFDAQI FTPNYLYDSNGNLATRPKITRTSTQSVKVGGRITISTDSSITKASLIRYGTATHT VNTDQRRIPLTLTNNGGNSYSFQVPSDSGVALPGYWMLFVMNSAGVPSVASTIRV TQAAA 207 GOh2087 atgggcagcagccatcatcatcatcatcacagcagcggcctggtgccgcgcggca gccatatgggtaccgcctctgcccctatcggctcagccatcccgcgcaataactg ggccgtaacgtgcgacagcgcgcagagcggcaacgagtgcaataaagccatcgac ggcaataaagacaccttctggcacacgttttatggcgcaaatggcgacccgaagc caccgcatacctataccattgacatgaaaaccacccagaatgtgaacgggctgtc cgtgctgccgcgccaggacggcaatcagaacggatggatcggccgtcacgaggta tatttaagctccgacggcaccaactggggatccccggtcgcgtcgggcagctggt tcgccgacagcaccaccaagtattccaattttgaaacccgtcctgcacgctacgt gcgcttagtggccgtgacagaggcgaacggccagccatggacctcaatcgccgaa atcaatgtattccaagccagctcctataccgcgccgcagccaggacttgggcgtt ggggcccgaccatcgacctgcctatcgtacccgcagccgcggcgattgaaccaac gtcaggccgcgtactgatgtggagcagctaccgtaacgacgcggcgtatggcagc ccgggcggcatcactctgacgtcgagttgggatccatccacgggcatcgtctccg accgcaccgtgaccgtcacgaaacacgacatgttttgcccggggatcagcatgga cggcaacggccagatcgtcgtcacgggcggctgggacgccaagaagacgagcctc tatgacagtagcagcgacagttggatcccggggccggacatgcaggtggcacgcg ggtaccagtccagcgcgaccatgtcagacggccgtgtctttacaatcggcggctc atttagtggcggagtgtttgagaagaatggcgaagtctatagcccctcatccaaa acgtggacgtcacttccgaacgcgaaggtgaatcccatgttaaccgccgacaaac agggcctgtacatgagcgacaaccatgcgtggctgttcggctggaagaaggggag cgtctttcaggcgggcccgtcgaccgcaatgaattggtattacacgtcaggaagc ggggacgtgaaatcagccggcaagcgccagtcgaaccgcggcgtggcgccggacg caatgtgcggcaatgccgtgatgtatgacgcggtcaaaggcaagatcctgacatt tggcgggagtccggactacaccgacagtgacgcgacaaccaatgcccacattatt acccttggggagccggggacgagcccgaacacggtcttcgcgtccaatggcctct atttcgcgcgtacctttcatacgtcggtggtcctgccggacggatcaacctttat caccggcggacagcgccgtggcatccccttcgaagactcgacccccgtctttaca ccggagatttatgtgccggaacaggacacgttttataaacagaatccgaactcga ttgtacgcgcgtatcactccatcagccttcttctcccggacggacgtgtctttaa tggcggaggaggactgtgcggggactgcacgaccaatcattttgacgcgcagatc tttaccccgaattatctgtatgattcaaatgggaatctcgcgacccgtccgaaaa ttacccgtacatcaacccagtccgtcaaagtgggcggccgcattacgatcagtac cgacagcagcattaccaaagcgtcactgattcgttacggcaccgcaacccataca gtcaacacggaccagcgccgtattccgttaaccctgaccaataacggtggcaatt cgtatagcttccaggtaccgtcggactcgggcgtggcgctgccaggatactggat gctgtttgtgatgaatagcgcgggcgtcccgagcgtagcgagcacgatccgtgtg acccaggccgcagcttgataa 208 GOh2087 MGSSHHHHHHSSGLVPRGSHMGTASAPIGSAIPRNNWAVTCDSAQSGNECNKAID GNKDTFWHTFYGANGDPKPPHTYTIDMKTTQNVNGLSVLPRQDGNQNGWIGRHEV YLSSDGTNWGSPVASGSWFADSTTKYSNFETRPARYVRLVAVTEANGQPWTSIAE INVFQASSYTAPQPGLGRWGPTIDLPIVPAAAAIEPTSGRVLMWSSYRNDAAYGS PGGITLTSSWDPSTGIVSDRTVTVTKHDMFCPGISMDGNGQIVVTGGWDAKKTSL YDSSSDSWIPGPDMQVARGYQSSATMSDGRVFTIGGSFSGGVFEKNGEVYSPSSK TWTSLPNAKVNPMLTADKQGLYMSDNHAWLFGWKKGSVFQAGPSTAMNWYYTSGS GDVKSAGKRQSNRGVAPDAMCGNAVMYDAVKGKILTFGGSPDYTDSDATTNAHII TLGEPGTSPNTVFASNGLYFARTFHTSVVLPDGSTFITGGQRRGIPFEDSTPVFT PEIYVPEQDTFYKQNPNSIVRAYHSISLLLPDGRVFNGGGGLCGDCTTNHFDAQI FTPNYLYDSNGNLATRPKITRTSTQSVKVGGRITISTDSSITKASLIRYGTATHT VNTDQRRIPLTLTNNGGNSYSFQVPSDSGVALPGYWMLFVMNSAGVPSVASTIRV TQAAA 209 GOh2088 atgggcagcagccatcatcatcatcatcacagcagcggcctggtgccgcgcggca gccatatgggtaccgcctctgcccctatcggctcagccatcccgcgcaataactg ggccgtaacgtgcgacagcgcgcagagcggcaacgagtgcaataaagccatcgac ggcaataaagacaccttctggcacacgttttatggcgcaaatggcgacccgaagc caccgcatacctataccattgacatgaaaaccacccagaatgtgaacgggctgtc cgtgctgccgcgccaggacggcaatcagaacggatggatcggccgtcacgaggta tatttaagctccgacggcaccaactggggatccccggtcgcgtcgggcagctggt tcgccgacagcaccaccaagtattccaattttgaaacccgtcctgcacgctacgt gcgcttagtggccgtgacagaggcgaacggccagccatggacctcaatcgccgaa atcaatgtattccaagccagctcctataccgcgccgcagccaggacttgggcgtt ggggcccgaccatcgacctgcctatcgtacccgcagccgcggcgattgaaccaac gtcaggccgcgtactgatgtggagcagctaccgtaacgacgcggcggaaggcagc ccgggcggcatcactgttacgtcgagttgggatccatccacgggcatcgtctccg accgcaccgtgaccgtcacgaaacacgacatgttttgcccggggatcagcatgga cggcaacggccagatcgtcgtcacgggcggctgggacgccaagaagacgagcctc tatgacagtagcagcgacagttggatcccggggccggacatgcaggtggcacgcg ggtaccagtccagcgcgaccatgtcagacggccgtgtctttacaatcggcggctc atttagtggcggagtgtttgagaagaatggcgaagtctatagcccctcatccaaa acgtggacgtcacttccgaacgcgaaggtgaatcccatgttaaccgccgacaaac agggcctgtacatgagcgacaaccatgcgtggctgttcggctggaagaaggggag cgtctttcaggcgggcccgtcgaccgcaatgaattggtattacacgtcaggaagc ggggacgtgaaatcagccggcaagcgccagtcgaaccgcggcgtggcgccggacg caatgtgcggcaatgccgtgatgtatgacgcggtcaaaggcaagatcctgacatt tggcgggagtccggactacaccgacagtgacgcgacaaccaatgcccacattatt acccttggggagccggggacgagcccgaacacggtcttcgcgtccaatggcctct atttcgcgcgtacctttcatacgtcggtggtcctgccggacggatcaacctttat caccggcggacagcgccgtggcatccccttcgaagactcgacccccgtctttaca ccggagatttatgtgccggaacaggacacgttttataaacagaatccgaactcga ttgtacgcgcgtatcactccatcagccttcttctcccggacggacgtgtctttaa tggcggaggaggactgtgcggggactgcacgaccaatcattttgacgcgcagatc tttaccccgaattatctgtatgattcaaatgggaatctcgcgacccgtccgaaaa ttacccgtacatcaacccagtccgtcaaagtgggcggccgcattacgatcagtac cgacagcagcattaccaaagcgtcactgattcgttacggcaccgcaacccataca gtcaacacggaccagcgccgtattccgttaaccctgaccaataacggtggcaatt cgtatagcttccaggtaccgtcggactcgggcgtggcgctgccaggatactggat gctgtttgtgatgaatagcgcgggcgtcccgagcgtagcgagcacgatccgtgtg acccaggccgcagcttgataa 210 GOh2088 MGSSHHHHHHSSGLVPRGSHMGTASAPIGSAIPRNNWAVTCDSAQSGNECNKAID GNKDTFWHTFYGANGDPKPPHTYTIDMKTTQNVNGLSVLPRQDGNQNGWIGRHEV YLSSDGTNWGSPVASGSWFADSTTKYSNFETRPARYVRLVAVTEANGQPWTSIAE INVFQASSYTAPQPGLGRWGPTIDLPIVPAAAAIEPTSGRVLMWSSYRNDAAEGS PGGITVTSSWDPSTGIVSDRTVTVTKHDMFCPGISMDGNGQIVVTGGWDAKKTSL YDSSSDSWIPGPDMQVARGYQSSATMSDGRVFTIGGSFSGGVFEKNGEVYSPSSK TWTSLPNAKVNPMLTADKQGLYMSDNHAWLFGWKKGSVFQAGPSTAMNWYYTSGS GDVKSAGKRQSNRGVAPDAMCGNAVMYDAVKGKILTFGGSPDYTDSDATTNAHII TLGEPGTSPNTVFASNGLYFARTFHTSVVLPDGSTFITGGQRRGIPFEDSTPVFT PEIYVPEQDTFYKQNPNSIVRAYHSISLLLPDGRVFNGGGGLCGDCTTNHFDAQI FTPNYLYDSNGNLATRPKITRTSTQSVKVGGRITISTDSSITKASLIRYGTATHT VNTDQRRIPLTLTNNGGNSYSFQVPSDSGVALPGYWMLFVMNSAGVPSVASTIRV TQAAA 211 GOh2089 atgggcagcagccatcatcatcatcatcacagcagcggcctggtgccgcgcggca gccatatgggtaccgcctctgcccctatcggctcagccatcccgcgcaataactg ggccgtaacgtgcgacagcgcgcagagcggcaacgagtgcaataaagccatcgac ggcaataaagacaccttctggcacacgttttatggcgcaaatggcgacccgaagc caccgcatacctataccattgacatgaaaaccacccagaatgtgaacgggctgtc cgtgctgccgcgccaggacggcaatcagaacggatggatcggccgtcacgaggta tatttaagctccgacggcaccaactggggatccccggtcgcgtcgggcagctggt tcgccgacagcaccaccaagtattccaattttgaaacccgtcctgcacgctacgt gcgcttagtggccgtgacagaggcgaacggccagccatggacctcaatcgccgaa atcaatgtattccaagccagctcctataccgcgccgcagccaggacttgggcgtt ggggcccgaccatcgacctgcctatcgtacccgcagccgcggcgattgaaccaac gtcaggccgcgtactgatgtggagcagctaccgtaacgacgcggcggaaggcagc ccgggcggcatcactctgacgtcgagttgggatccatccacgggcatcgtctccc agcgcaccgtgaccgtcacgaaacacgacatgttttgcccggggatcagcatgga cggcaacggccagatcgtcgtcacgggcggctgggacgccaagaagacgagcctc tatgacagtagcagcgacagttggatcccggggccggacatgcaggtggcacgcg ggtaccagtccagcgcgaccatgtcagacggccgtgtctttacaatcggcggctc atttagtggcggagtgtttgagaagaatggcgaagtctatagcccctcatccaaa acgtggacgtcacttccgaacgcgaaggtgaatcccatgttaaccgccgacaaac agggcctgtacatgagcgacaaccatgcgtggctgttcggctggaagaaggggag cgtctttcaggcgggcccgtcgaccgcaatgaattggtattacacgtcaggaagc ggggacgtgaaatcagccggcaagcgccagtcgaaccgcggcgtggcgccggacg caatgtgcggcaatgccgtgatgtatgacgcggtcaaaggcaagatcctgacatt tggcgggagtccggactacaccgacagtgacgcgacaaccaatgcccacattatt acccttggggagccggggacgagcccgaacacggtcttcgcgtccaatggcctct atttcgcgcgtacctttcatacgtcggtggtcctgccggacggatcaacctttat caccggcggacagcgccgtggcatccccttcgaagactcgacccccgtctttaca ccggagatttatgtgccggaacaggacacgttttataaacagaatccgaactcga ttgtacgcgcgtatcactccatcagccttcttctcccggacggacgtgtctttaa tggcggaggaggactgtgcggggactgcacgaccaatcattttgacgcgcagatc tttaccccgaattatctgtatgattcaaatgggaatctcgcgacccgtccgaaaa ttacccgtacatcaacccagtccgtcaaagtgggcggccgcattacgatcagtac cgacagcagcattaccaaagcgtcactgattcgttacggcaccgcaacccataca gtcaacacggaccagcgccgtattccgttaaccctgaccaataacggtggcaatt cgtatagcttccaggtaccgtcggactcgggcgtggcgctgccaggatactggat gctgtttgtgatgaatagcgcgggcgtcccgagcgtagcgagcacgatccgtgtg acccaggccgcagcttgataa 212 GOh2089 MGSSHHHHHHSSGLVPRGSHMGTASAPIGSAIPRNNWAVTCDSAQSGNECNKAID GNKDTFWHTFYGANGDPKPPHTYTIDMKTTQNVNGLSVLPRQDGNQNGWIGRHEV YLSSDGTNWGSPVASGSWFADSTTKYSNFETRPARYVRLVAVTEANGQPWTSIAE INVFQASSYTAPQPGLGRWGPTIDLPIVPAAAAIEPTSGRVLMWSSYRNDAAEGS PGGITLTSSWDPSTGIVSQRTVTVTKHDMFCPGISMDGNGQIVVTGGWDAKKTSL YDSSSDSWIPGPDMQVARGYQSSATMSDGRVFTIGGSFSGGVFEKNGEVYSPSSK TWTSLPNAKVNPMLTADKQGLYMSDNHAWLFGWKKGSVFQAGPSTAMNWYYTSGS GDVKSAGKRQSNRGVAPDAMCGNAVMYDAVKGKILTFGGSPDYTDSDATTNAHII TLGEPGTSPNTVFASNGLYFARTFHTSVVLPDGSTFITGGQRRGIPFEDSTPVFT PEIYVPEQDTFYKQNPNSIVRAYHSISLLLPDGRVFNGGGGLCGDCTTNHFDAQI FTPNYLYDSNGNLATRPKITRTSTQSVKVGGRITISTDSSITKASLIRYGTATHT VNTDQRRIPLTLTNNGGNSYSFQVPSDSGVALPGYWMLFVMNSAGVPSVASTIRV TQAAA 213 GOh2090 atgggcagcagccatcatcatcatcatcacagcagcggcctggtgccgcgcggca gccatatgggtaccgcctctgcccctatcggctcagccatcccgcgcaataactg ggccgtaacgtgcgacagcgcgcagagcggcaacgagtgcaataaagccatcgac ggcaataaagacaccttctggcacacgttttatggcgcaaatggcgacccgaagc caccgcatacctataccattgacatgaaaaccacccagaatgtgaacgggctgtc cgtgctgccgcgccaggacggcaatcagaacggatggatcggccgtcacgaggta tatttaagctccgacggcaccaactggggatccccggtcgcgtcgggcagctggt tcgccgacagcaccaccaagtattccaattttgaaacccgtcctgcacgctacgt gcgcttagtggccgtgacagaggcgaacggccagccatggacctcaatcgccgaa atcaatgtattccaagccagctcctataccgcgccgcagccaggacttgggcgtt ggggcccgaccatcgacctgcctatcgtacccgcagccgcggcgattgaaccaac gtcaggccgcgtactgatgtggagcagctaccgtaacgacgcggcggaaggcagc ccgggcggcatcactctgacgtcgagttgggatccatccacgggcatcgtctccg accgcaccgtgaccgtcacgaaacacgacatgttttgcccggggatcagcatgga cggcaacggccagatcgtcgtcacgggcggctgggacgccaagaagacgagcctc tatgacagtagcagcgacagttggatcccggggccggacatgcaggtggcacgcg ggtaccagtccagcgcgaccatgtcagacggccgtgtctttacaatcggcggctc atttagtggcggagtgtttgagaagaatggcgaagtctatagcccctcatccaaa acgtggacgtcacttccgaacgcgaaggtgaatcccatgttaaccgccgacaaac agggcctgtacatgagcgacaaccatgcgtggctgttcggctggaagaaggggag cgtctttcaggcgggcccgtcgaccgcaatgaattggtattacacgtcaggaagc ggggacgtgaaatcagccggcaagcgccagtcgaaccgcggcgtggcgccggacg caatgtgcggcaatgccgtgatgtatgacgcggtcaaaggcaagatcctgacatt tggcgggagtccggactacaccgacagtgacgcgacaaccaatgcccacattatt acccttggggagccggggacgagcccgaacacggtcttcgcgtccaatggcctct atttcgcgcgtacctttcatacgtcggtggtcctgccggacggatcaacctttat caccggcggacagcgccgtggcatccccttcgaagactcgacccccgtctttaca ccggagatttatgtgccggaacaggacacgttttataaacagaatccgaactcga ttgtacgcgcgtatcactccatcagccttcttctcccggacggacgtgtctttaa tggcggaggaggactgtgcggggactgcacgaccaatcacatggacgcgcagatc tttaccccgaattatctgtatgattcaaatgggaatctcgcgacccgtccgaaaa ttacccgtacatcaacccagtccgtcaaagtgggcggccgcattacgatcagtac cgacagcagcattaccaaagcgtcactgattcgttacggcaccgcaacccataca gtcaacacggaccagcgccgtattccgttaaccctgaccaataacggtggcaatt cgtatagcttccaggtaccgtcggactcgggcgtggcgctgccaggatactggat gctgtttgtgatgaatagcgcgggcgtcccgagcgtagcgagcacgatccgtgtg acccaggccgcagcttgataa 214 GOh2090 MGSSHHHHHHSSGLVPRGSHMGTASAPIGSAIPRNNWAVTCDSAQSGNECNKAID GNKDTFWHTFYGANGDPKPPHTYTIDMKTTQNVNGLSVLPRQDGNQNGWIGRHEV YLSSDGTNWGSPVASGSWFADSTTKYSNFETRPARYVRLVAVTEANGQPWTSIAE INVFQASSYTAPQPGLGRWGPTIDLPIVPAAAAIEPTSGRVLMWSSYRNDAAEGS PGGITLTSSWDPSTGIVSDRTVTVTKHDMFCPGISMDGNGQIVVTGGWDAKKTSL YDSSSDSWIPGPDMQVARGYQSSATMSDGRVFTIGGSFSGGVFEKNGEVYSPSSK TWTSLPNAKVNPMLTADKQGLYMSDNHAWLFGWKKGSVFQAGPSTAMNWYYTSGS GDVKSAGKRQSNRGVAPDAMCGNAVMYDAVKGKILTFGGSPDYTDSDATTNAHII TLGEPGTSPNTVFASNGLYFARTFHTSVVLPDGSTFITGGQRRGIPFEDSTPVFT PEIYVPEQDTFYKQNPNSIVRAYHSISLLLPDGRVFNGGGGLCGDCTTNHMDAQI FTPNYLYDSNGNLATRPKITRTSTQSVKVGGRITISTDSSITKASLIRYGTATHT VNTDQRRIPLTLTNNGGNSYSFQVPSDSGVALPGYWMLFVMNSAGVPSVASTIRV TQAAA 215 GOh2091 atgggcagcagccatcatcatcatcatcacagcagcggcctggtgccgcgcggca gccatatgggtaccaattctgcccctatcggctcagccatcccgcgcaataactg ggccgtaacgtgcgacagcgcgcagagcggcaacgagtgcaataaagccatcgac ggcaataaagacaccttctggcacacgttttatggcgcaaatggcgacccgaagc caccgcatacctataccattgacatgaaaaccacccagaatgtgaacgggctgtc cgtgctgccgcgccaggacggcaatcagaacggatggatcggccgtcacgaggta tatttaagctccgacggcaccaactggggatccccggtcgcgtcgggcagctggt tcgccgacagcaccaccaagtattccaattttgaaacccgtcctgcacgctacgt gcgcttagtggccgtgacagaggcgaacggccagccatggacctcaatcgccgaa atcaatgtattccaagccagctcctataccgcgccgcagccaggacttgggcgtt ggggcccgaccatcgacctgcctatcgtacccgcagccgcggcgattgaaccaac gtcaggccgcgtactgatgtggagcagctaccgtaacgacgcggcggaaggcagc ccgggcggcatcactctgacgtcgagttgggatccatccacgggcatcgtctccg accgcaccgtgaccgtcacgaaacacgacatgttttgcccggggatcagcatgga cggcaacggccagatcgtcgtcacgggcggctgggacgccaagaagacgagcctc tatgacagtagcagcgacagttggatcccggggccggacatgcaggtggcacgcg ggtaccagtccagcgcgaccatgtcagacggccgtgtctttacaatcggcggctc atttagtggcggagtgtttgagaagaatggcgaagtctatagcccctcatccaaa acgtggacgtcacttccgaacgcgaaggtgaatcccatgttaaccgccgacaaac agggcctgtacatgagcgacaaccatgcgtggctgttcggctggaagaaggggag cgtctttcaggcgggcccgtcgaccgcaatgaattggtattacacgtcaggaagc ggggacgtgaaatcagccggcaagcgccagtcgaaccgcggcgtggcgccggacg caatgtgcggcaatgccgtgatgtatgacgcggtcaaaggcaagatcctgacatt tggcgggagtccggactacaccgacagtgacgcgacaaccaatgcccacattatt acccttggggagccggggacgagcccgaacacggtcttcgcgtccaatggcctct atttcgcgcgtacctttcatacgtcggtggtcctgccggacggatcaacctttat caccggcggacagcgccgtggcatccccttcgaagactcgacccccgtctttaca ccggagatttatgtgccggaacaggacacgttttataaacagaatccgaactcga ttgtacgcgcgtatcactccatcagccttcttctcccggacggacgtgtctttaa tggcggaggaggactgtgcggggactgcacgaccaatcattttgacgcgcagatc tttaccccgaattatctgtatgattcaaatgggaatctcgcgacccgtccgaaaa ttacccgtacatcaacccagtccgtcaaagtgggcggccgcattacgatcagtac cgacagcagcattaccaaagcgtcactgattcgttacggcaccgcaacccataca gtcaacacggaccagcgccgtattccgttaaccctgaccaataacggtggcaatt cgtatagcttccaggtaccgtcggactcgggcgtggcgctgccaggatactggat gctgtttgtgatgaatagcgcgggcgtcccgagcgtagcgagcacgatccgtgtg acccaggccgcagcttgataa 216 GOh2091 MGSSHHHHHHSSGLVPRGSHMGTNSAPIGSAIPRNNWAVTCDSAQSGNECNKAID GNKDTFWHTFYGANGDPKPPHTYTIDMKTTQNVNGLSVLPRQDGNQNGWIGRHEV YLSSDGTNWGSPVASGSWFADSTTKYSNFETRPARYVRLVAVTEANGQPWTSIAE INVFQASSYTAPQPGLGRWGPTIDLPIVPAAAAIEPTSGRVLMWSSYRNDAAEGS PGGITLTSSWDPSTGIVSDRTVTVTKHDMFCPGISMDGNGQIVVTGGWDAKKTSL YDSSSDSWIPGPDMQVARGYQSSATMSDGRVFTIGGSFSGGVFEKNGEVYSPSSK TWTSLPNAKVNPMLTADKQGLYMSDNHAWLFGWKKGSVFQAGPSTAMNWYYTSGS GDVKSAGKRQSNRGVAPDAMCGNAVMYDAVKGKILTFGGSPDYTDSDATTNAHII TLGEPGTSPNTVFASNGLYFARTFHTSVVLPDGSTFITGGQRRGIPFEDSTPVFT PEIYVPEQDTFYKQNPNSIVRAYHSISLLLPDGRVFNGGGGLCGDCTTNHFDAQI FTPNYLYDSNGNLATRPKITRTSTQSVKVGGRITISTDSSITKASLIRYGTATHT VNTDQRRIPLTLTNNGGNSYSFQVPSDSGVALPGYWMLFVMNSAGVPSVASTIRV TQAAA 217 GOh2092 atgggcagcagccatcatcatcatcatcacagcagcggcctggtgccgcgcggca gccatatgggtaccgcctctcatcctatcggctcagccatcccgcgcaataactg ggccgtaacgtgcgacagcgcgcagagcggcaacgagtgcaataaagccatcgac ggcaataaagacaccttctggcacacgttttatggcgcaaatggcgacccgaagc caccgcatacctataccattgacatgaaaaccacccagaatgtgaacgggctgtc cgtgctgccgcgccaggacggcaatcagaacggatggatcggccgtcacgaggta tatttaagctccgacggcaccaactggggatccccggtcgcgtcgggcagctggt tcgccgacagcaccaccaagtattccaattttgaaacccgtcctgcacgctacgt gcgcttagtggccgtgacagaggcgaacggccagccatggacctcaatcgccgaa atcaatgtattccaagccagctcctataccgcgccgcagccaggacttgggcgtt ggggcccgaccatcgacctgcctatcgtacccgcagccgcggcgattgaaccaac gtcaggccgcgtactgatgtggagcagctaccgtaacgacgcggcggaaggcagc ccgggcggcatcactctgacgtcgagttgggatccatccacgggcatcgtctccg accgcaccgtgaccgtcacgaaacacgacatgttttgcccggggatcagcatgga cggcaacggccagatcgtcgtcacgggcggctgggacgccaagaagacgagcctc tatgacagtagcagcgacagttggatcccggggccggacatgcaggtggcacgcg ggtaccagtccagcgcgaccatgtcagacggccgtgtctttacaatcggcggctc atttagtggcggagtgtttgagaagaatggcgaagtctatagcccctcatccaaa acgtggacgtcacttccgaacgcgaaggtgaatcccatgttaaccgccgacaaac agggcctgtacatgagcgacaaccatgcgtggctgttcggctggaagaaggggag cgtctttcaggcgggcccgtcgaccgcaatgaattggtattacacgtcaggaagc ggggacgtgaaatcagccggcaagcgccagtcgaaccgcggcgtggcgccggacg caatgtgcggcaatgccgtgatgtatgacgcggtcaaaggcaagatcctgacatt tggcgggagtccggactacaccgacagtgacgcgacaaccaatgcccacattatt acccttggggagccggggacgagcccgaacacggtcttcgcgtccaatggcctct atttcgcgcgtacctttcatacgtcggtggtcctgccggacggatcaacctttat caccggcggacagcgccgtggcatccccttcgaagactcgacccccgtctttaca ccggagatttatgtgccggaacaggacacgttttataaacagaatccgaactcga ttgtacgcgcgtatcactccatcagccttcttctcccggacggacgtgtctttaa tggcggaggaggactgtgcggggactgcacgaccaatcattttgacgcgcagatc tttaccccgaattatctgtatgattcaaatgggaatctcgcgacccgtccgaaaa ttacccgtacatcaacccagtccgtcaaagtgggcggccgcattacgatcagtac cgacagcagcattaccaaagcgtcactgattcgttacggcaccgcaacccataca gtcaacacggaccagcgccgtattccgttaaccctgaccaataacggtggcaatt cgtatagcttccaggtaccgtcggactcgggcgtggcgctgccaggatactggat gctgtttgtgatgaatagcgcgggcgtcccgagcgtagcgagcacgatccgtgtg acccaggccgcagcttgataa 218 GOh2092 MGSSHHHHHHSSGLVPRGSHMGTASHPIGSAIPRNNWAVTCDSAQSGNECNKAID GNKDTFWHTFYGANGDPKPPHTYTIDMKTTQNVNGLSVLPRQDGNQNGWIGRHEV YLSSDGTNWGSPVASGSWFADSTTKYSNFETRPARYVRLVAVTEANGQPWTSIAE INVFQASSYTAPQPGLGRWGPTIDLPIVPAAAAIEPTSGRVLMWSSYRNDAAEGS PGGITLTSSWDPSTGIVSDRTVTVTKHDMFCPGISMDGNGQIVVTGGWDAKKTSL YDSSSDSWIPGPDMQVARGYQSSATMSDGRVFTIGGSFSGGVFEKNGEVYSPSSK TWTSLPNAKVNPMLTADKQGLYMSDNHAWLFGWKKGSVFQAGPSTAMNWYYTSGS GDVKSAGKRQSNRGVAPDAMCGNAVMYDAVKGKILTFGGSPDYTDSDATTNAHII TLGEPGTSPNTVFASNGLYFARTFHTSVVLPDGSTFITGGQRRGIPFEDSTPVFT PEIYVPEQDTFYKQNPNSIVRAYHSISLLLPDGRVFNGGGGLCGDCTTNHFDAQI FTPNYLYDSNGNLATRPKITRTSTQSVKVGGRITISTDSSITKASLIRYGTATHT VNTDQRRIPLTLTNNGGNSYSFQVPSDSGVALPGYWMLFVMNSAGVPSVASTIRV TQAAA 219 GOh2093 atgggcagcagccatcatcatcatcatcacagcagcggcctggtgccgcgcggca gccatatgggtaccgcctctgcccctatcggctcagccatcccgcgcaataactg ggccgtaacgtgcgacagcgcgcagagcggcaacgagtgcaataaagccatcgac ggcaataaagacaccttctggcacacgttttatggcgcaaatggcgacccgaagc caccgcatacctataccattgacatgaaaaccacccagaatgtgaacgggctgtc cgtgctgccgcgccaggacggcaatcagaacggatggatcggccgtcacgaggta tatttaagctccgacggcaccaactggggatccccggtcgcgtcgggcagctggt tcgccgacagcaccaccaagtattccaattttgaaacccgtcctgcacgctacgt gcgcttagtggccgtgacagaggcgaacggccagccatggacctcaatcgccgaa atcaatgtattccaagccagctcctataccgcgccgcagccaggacttgggcgtt ggggcccgaccatcgacctgcctatcgtacccgcagccgcggcgattgaaccaac gtcaggccgcgtactgatgtggagcagctaccgtaacgacgcggcggaaggcagc ccgggcggcatcactctgacgtcgagttgggatccatccacgggcatcgtctccg accgcaccgtgaccgtcacgaaacacgacatgttttgcccggggatcagcatgga cggcaacggccagatcgtcgtcacgggcggctgggacgccaagaagacgagcctc tatgacagtagcagcgacagttggatcccggggccggacatgcaggtggcacgcg ggtaccagtccagcgcgaccatgtcagacggccgtgtctttacaatcggcggctc atttagtggcggagtgtttgagaagaatggcgaagtctatagcccctcatccaaa acgtggacgtcacttccgaacgcgaaggtgaatcccatgttaaccgccgacaaac agggcctgtacatgagcgacaaccatgcgtggctgttcggctggaagaaggggag cgtctttcaggcgggcccgtcgaccgcaatgaattggtattacacgtcaggaagc ggggacgtgaaatcagccggcaagcgccagtcgaaccgcggcgtggcgccggacg caatgtgcggcaatgccgtgatgtatgacgcggtcaaaggcaagatcctgacatt tggcgggagtccggactacaccgacagtgacgcgacaaccaatgcccacattatt acccttggggagccggggacgagcccgaacacggtcttcgcgtccaatggcctct atttcgcgcgtacctttcatacgtcggtggtcctgccggacggatcaacctttat caccggcggacagcgccgtggcatccccttcgaagactcgacccccgtctttaca ccggagatttatgtgccggaacaggacacgttttataaacagaatccgaactcga ttgtacgcgcgtatcactccatcagccttcttctcccggacggacgtgtctttaa tggcggaggaggactgtgcggggactgcacgaccaatcattttgacgcgcagatc tttaccccgaattatctgtatgattcaaatgggaatctcgcgacccgtccgaaaa ttacccgtacatcaacccagtccgtcaaagtgggcggccgcattacgatcagtac cgacagcagcattaccaaagcgtcactgattcgtatgggcaccgcaacccataca gtcaacacggaccagcgccgtattccgttaaccctgaccaataacggtggcaatt cgtatagcttccaggtaccgtcggactcgggcgtggcgctgccaggatactggat gctgtttgtgatgaatagcgcgggcgtcccgagcgtagcgagcacgatccgtgtg acccaggccgcagcttgataa 220 GOh2093 MGSSHHHHHHSSGLVPRGSHMGTASAPIGSAIPRNNWAVTCDSAQSGNECNKAID GNKDTFWHTFYGANGDPKPPHTYTIDMKTTQNVNGLSVLPRQDGNQNGWIGRHEV YLSSDGTNWGSPVASGSWFADSTTKYSNFETRPARYVRLVAVTEANGQPWTSIAE INVFQASSYTAPQPGLGRWGPTIDLPIVPAAAAIEPTSGRVLMWSSYRNDAAEGS PGGITLTSSWDPSTGIVSDRTVTVTKHDMFCPGISMDGNGQIVVTGGWDAKKTSL YDSSSDSWIPGPDMQVARGYQSSATMSDGRVFTIGGSFSGGVFEKNGEVYSPSSK TWTSLPNAKVNPMLTADKQGLYMSDNHAWLFGWKKGSVFQAGPSTAMNWYYTSGS GDVKSAGKRQSNRGVAPDAMCGNAVMYDAVKGKILTFGGSPDYTDSDATTNAHII TLGEPGTSPNTVFASNGLYFARTFHTSVVLPDGSTFITGGQRRGIPFEDSTPVFT PEIYVPEQDTFYKQNPNSIVRAYHSISLLLPDGRVFNGGGGLCGDCTTNHFDAQI FTPNYLYDSNGNLATRPKITRTSTQSVKVGGRITISTDSSITKASLIRMGTATHT VNTDQRRIPLTLTNNGGNSYSFQVPSDSGVALPGYWMLFVMNSAGVPSVASTIRV TQAAA 221 GOh2094 atgggcagcagccatcatcatcatcatcacagcagcggcctggtgccgcgcggca gccatatgggtaccgcctctgcccctatcggctcagccatcccgcgcaataactg ggccgtaacgtgcgacagcgcgcagagcggcaacgagtgcaataaagccatcgac ggcaataaagacaccttctggcacacgttttatggcgcaaatggcgacccgaagc caccgcatacctataccattgacatgaaaaccacccagaatgtgaacgggctgtc cgtgctgccgcgccaggacggcaatcagaacggatggatcggccgtcacgaggta tatttaagctccgacggcaccaactggggatccccggtcgcgtcgggcagctggt tcgccgacagcaccaccaagtattccaattttgaaacccgtcctgcacgctacgt gcgcttagtggccgtgacagaggcgaacaatcagccatggacctcaatcgccgaa atcaatgtattccaagccagctcctataccgcgccgcagccaggacttgggcgtt ggggcccgaccatcgacctgcctatcgtacccgcagccgcggcgattgaaccaac gtcaggccgcgtactgatgtggagcagctaccgtaacgacgcggcggaaggcagc ccgggcggcatcactctgacgtcgagttgggatccatccacgggcatcgtctccg accgcaccgtgaccgtcacgaaacacgacatgttttgcccggggatcagcatgga cggcaacggccagatcgtcgtcacgggcggctgggacgccaagaagacgagcctc tatgacagtagcagcgacagttggatcccggggccggacatgcaggtggcacgcg ggtaccagtccagcgcgaccatgtcagacggccgtgtctttacaatcggcggctc atttagtggcggagtgtttgagaagaatggcgaagtctatagcccctcatccaaa acgtggacgtcacttccgaacgcgaaggtgaatcccatgttaaccgccgacaaac agggcctgtacatgagcgacaaccatgcgtggctgttcggctggaagaaggggag cgtctttcaggcgggcccgtcgaccgcaatgaattggtattacacgtcaggaagc ggggacgtgaaatcagccggcaagcgccagtcgaaccgcggcgtggcgccggacg caatgtgcggcaatgccgtgatgtatgacgcggtcaaaggcaagatcctgacatt tggcgggagtccggactacaccgacagtgacgcgacaaccaatgcccacattatt acccttggggagccggggacgagcccgaacacggtcttcgcgtccaatggcctct atttcgcgcgtacctttcatacgtcggtggtcctgccggacggatcaacctttat caccggcggacagcgccgtggcatccccttcgaagactcgacccccgtctttaca ccggagatttatgtgccggaacaggacacgttttataaacagaatccgaactcga ttgtacgcgcgtatcactccatcagccttcttctcccggacggacgtgtctttaa tggcggaggaggactgtgcggggactgcacgaccaatcattttgacgcgcagatc tttaccccgaattatctgtatgattcaaatgggaatctcgcgacccgtccgaaaa ttacccgtacatcaacccagtccgtcaaagtgggcggccgcattacgatcagtac cgacagcagcattaccaaagcgtcactgattcgttacggcaccgcaacccataca gtcaacacggaccagcgccgtattccgttaaccctgaccaataacggtggcaatt cgtatagcttccaggtaccgtcggactcgggcgtggcgctgccaggatactggat gctgtttgtgatgaatagcgcgggcgtcccgagcgtagcgagcacgatccgtgtg acccaggccgcagcttgataa 222 GOh2094 MGSSHHHHHHSSGLVPRGSHMGTASAPIGSAIPRNNWAVTCDSAQSGNECNKAID GNKDTFWHTFYGANGDPKPPHTYTIDMKTTQNVNGLSVLPRQDGNQNGWIGRHEV YLSSDGTNWGSPVASGSWFADSTTKYSNFETRPARYVRLVAVTEANNQPWTSIAE INVFQASSYTAPQPGLGRWGPTIDLPIVPAAAAIEPTSGRVLMWSSYRNDAAEGS PGGITLTSSWDPSTGIVSDRTVTVTKHDMFCPGISMDGNGQIVVTGGWDAKKTSL YDSSSDSWIPGPDMQVARGYQSSATMSDGRVFTIGGSFSGGVFEKNGEVYSPSSK TWTSLPNAKVNPMLTADKQGLYMSDNHAWLFGWKKGSVFQAGPSTAMNWYYTSGS GDVKSAGKRQSNRGVAPDAMCGNAVMYDAVKGKILTFGGSPDYTDSDATTNAHII TLGEPGTSPNTVFASNGLYFARTFHTSVVLPDGSTFITGGQRRGIPFEDSTPVFT PEIYVPEQDTFYKQNPNSIVRAYHSISLLLPDGRVFNGGGGLCGDCTTNHFDAQI FTPNYLYDSNGNLATRPKITRTSTQSVKVGGRITISTDSSITKASLIRYGTATHT VNTDQRRIPLTLTNNGGNSYSFQVPSDSGVALPGYWMLFVMNSAGVPSVASTIRV TQAAA 223 GOh2097 atgggcagcagccatcatcatcatcatcacagcagcggcctggtgccgcgcggca gccatatgggtaccgcctctgcccctatcggctcagccatcccgcgcaataactg ggccgtaacgtgcgacagcgcggatagcggcaacgagtgcaataaagccatcgac ggcaataaagacaccttctggcacacgttttatggcgcaaatggcgacccgaagc caccgcatacctataccattgacatgaaaaccacccagaatgtgaacgggctgtc cgtgctgccgcgccaggacggcaatcagaacggatggatcggccgtcacgaggta tatttaagctccgacggcaccaactggggatccccggtcgcgtcgggcagctggt tcgccgacagcaccaccaagtattccaattttgaaacccgtcctgcacgctacgt gcgcttagtggccgtgacagaggcgaacggccagccatggacctcaatcgccgaa atcaatgtattccaagccagctcctataccgcgccgcagccaggacttgggcgtt ggggcccgaccatcgacctgcctatcgtacccgcagccgcggcgattgaaccaac gtcaggccgcgtactgatgtggagcagctaccgtaacgacgcggcggaaggcagc ccgggcggcatcactctgacgtcgagttgggatccatccacgggcatcgtctccg accgcaccgtgaccgtcacgaaacacgacatgttttgcccggggatcagcatgga cggcaacggccagatcgtcgtcacgggcggctgggacgccaagaagacgagcctc tatgacagtagcagcgacagttggatcccggggccggacatgcaggtggcacgcg ggtaccagtccagcgcgaccatgtcagacggccgtgtctttacaatcggcggctc atttagtggcggagtgtttgagaagaatggcgaagtctatagcccctcatccaaa acgtggacgtcacttccgaacgcgaaggtgaatcccatgttaaccgccgacaaac agggcctgtacatgagcgacaaccatgcgtggctgttcggctggaagaaggggag cgtctttcaggcgggcccgtcgaccgcaatgaattggtattacacgtcaggaagc ggggacgtgaaatcagccggcaagcgccagtcgaaccgcggcgtggcgccggacg caatgtgcggcaatgccgtgatgtatgacgcggtcaaaggcaagatcctgacatt tggcgggagtccggactacaccgacagtgacgcgacaaccaatgcccacattatt acccttggggagccggggacgagcccgaacacggtcttcgcgtccaatggcctct atttcgcgcgtacctttcatacgtcggtggtcctgccggacggatcaacctttat caccggcggacagcgccgtggcatccccttcgaagactcgacccccgtctttaca ccggagatttatgtgccggaacaggacacgttttataaacagaatccgaactcga ttgtacgcgcgtatcactccatcagccttcttctcccggacggacgtgtctttaa tggcggaggaggactgtgcggggactgcacgaccaatcattttgacgcgcagatc tttaccccgaattatctgtatgattcaaatgggaatctcgcgacccgtccgaaaa ttacccgtacatcaacccagtccgtcaaagtgggcggccgcattacgatcagtac cgacagcagcattaccaaagcgtcactgattcgttacggcaccgcaacccataca gtcaacacggaccagcgccgtattccgttaaccctgaccaataacggtggcaatt cgtatagcttccaggtaccgtcggactcgggcgtggcgctgccaggatactggat gctgtttgtgatgaatagcgcgggcgtcccgagcgtagcgagcacgatccgtgtg acccaggccgcagcttgataa 224 GOh2097 MGSSHHHHHHSSGLVPRGSHMGTASAPIGSAIPRNNWAVTCDSADSGNECNKAID GNKDTFWHTFYGANGDPKPPHTYTIDMKTTQNVNGLSVLPRQDGNQNGWIGRHEV YLSSDGTNWGSPVASGSWFADSTTKYSNFETRPARYVRLVAVTEANGQPWTSIAE INVFQASSYTAPQPGLGRWGPTIDLPIVPAAAAIEPTSGRVLMWSSYRNDAAEGS PGGITLTSSWDPSTGIVSDRTVTVTKHDMFCPGISMDGNGQIVVTGGWDAKKTSL YDSSSDSWIPGPDMQVARGYQSSATMSDGRVFTIGGSFSGGVFEKNGEVYSPSSK TWTSLPNAKVNPMLTADKQGLYMSDNHAWLFGWKKGSVFQAGPSTAMNWYYTSGS GDVKSAGKRQSNRGVAPDAMCGNAVMYDAVKGKILTFGGSPDYTDSDATTNAHII TLGEPGTSPNTVFASNGLYFARTFHTSVVLPDGSTFITGGQRRGIPFEDSTPVFT PEIYVPEQDTFYKQNPNSIVRAYHSISLLLPDGRVFNGGGGLCGDCTTNHFDAQI FTPNYLYDSNGNLATRPKITRTSTQSVKVGGRITISTDSSITKASLIRYGTATHT VNTDQRRIPLTLTNNGGNSYSFQVPSDSGVALPGYWMLFVMNSAGVPSVASTIRV TQAAA 225 GOh2098 atgggcagcagccatcatcatcatcatcacagcagcggcctggtgccgcgcggca gccatatgggtaccgcctctgcccctatcggctcagccatcccgcgcaataactg ggccgtaacgtgcgacagcgcggaaagcggcaacgagtgcaataaagccatcgac ggcaataaagacaccttctggcacacgttttatggcgcaaatggcgacccgaagc caccgcatacctataccattgacatgaaaaccacccagaatgtgaacgggctgtc cgtgctgccgcgccaggacggcaatcagaacggatggatcggccgtcacgaggta tatttaagctccgacggcaccaactggggatccccggtcgcgtcgggcagctggt tcgccgacagcaccaccaagtattccaattttgaaacccgtcctgcacgctacgt gcgcttagtggccgtgacagaggcgaacggccagccatggacctcaatcgccgaa atcaatgtattccaagccagctcctataccgcgccgcagccaggacttgggcgtt ggggcccgaccatcgacctgcctatcgtacccgcagccgcggcgattgaaccaac gtcaggccgcgtactgatgtggagcagctaccgtaacgacgcggcggaaggcagc ccgggcggcatcactctgacgtcgagttgggatccatccacgggcatcgtctccg accgcaccgtgaccgtcacgaaacacgacatgttttgcccggggatcagcatgga cggcaacggccagatcgtcgtcacgggcggctgggacgccaagaagacgagcctc tatgacagtagcagcgacagttggatcccggggccggacatgcaggtggcacgcg ggtaccagtccagcgcgaccatgtcagacggccgtgtctttacaatcggcggctc atttagtggcggagtgtttgagaagaatggcgaagtctatagcccctcatccaaa acgtggacgtcacttccgaacgcgaaggtgaatcccatgttaaccgccgacaaac agggcctgtacatgagcgacaaccatgcgtggctgttcggctggaagaaggggag cgtctttcaggcgggcccgtcgaccgcaatgaattggtattacacgtcaggaagc ggggacgtgaaatcagccggcaagcgccagtcgaaccgcggcgtggcgccggacg caatgtgcggcaatgccgtgatgtatgacgcggtcaaaggcaagatcctgacatt tggcgggagtccggactacaccgacagtgacgcgacaaccaatgcccacattatt acccttggggagccggggacgagcccgaacacggtcttcgcgtccaatggcctct atttcgcgcgtacctttcatacgtcggtggtcctgccggacggatcaacctttat caccggcggacagcgccgtggcatccccttcgaagactcgacccccgtctttaca ccggagatttatgtgccggaacaggacacgttttataaacagaatccgaactcga ttgtacgcgcgtatcactccatcagccttcttctcccggacggacgtgtctttaa tggcggaggaggactgtgcggggactgcacgaccaatcattttgacgcgcagatc tttaccccgaattatctgtatgattcaaatgggaatctcgcgacccgtccgaaaa ttacccgtacatcaacccagtccgtcaaagtgggcggccgcattacgatcagtac cgacagcagcattaccaaagcgtcactgattcgttacggcaccgcaacccataca gtcaacacggaccagcgccgtattccgttaaccctgaccaataacggtggcaatt cgtatagcttccaggtaccgtcggactcgggcgtggcgctgccaggatactggat gctgtttgtgatgaatagcgcgggcgtcccgagcgtagcgagcacgatccgtgtg acccaggccgcagcttgataa 226 GOh2098 MGSSHHHHHHSSGLVPRGSHMGTASAPIGSAIPRNNWAVTCDSAESGNECNKAID GNKDTFWHTFYGANGDPKPPHTYTIDMKTTQNVNGLSVLPRQDGNQNGWIGRHEV YLSSDGTNWGSPVASGSWFADSTTKYSNFETRPARYVRLVAVTEANGQPWTSIAE INVFQASSYTAPQPGLGRWGPTIDLPIVPAAAAIEPTSGRVLMWSSYRNDAAEGS PGGITLTSSWDPSTGIVSDRTVTVTKHDMFCPGISMDGNGQIVVTGGWDAKKTSL YDSSSDSWIPGPDMQVARGYQSSATMSDGRVFTIGGSFSGGVFEKNGEVYSPSSK TWTSLPNAKVNPMLTADKQGLYMSDNHAWLFGWKKGSVFQAGPSTAMNWYYTSGS GDVKSAGKRQSNRGVAPDAMCGNAVMYDAVKGKILTFGGSPDYTDSDATTNAHII TLGEPGTSPNTVFASNGLYFARTFHTSVVLPDGSTFITGGQRRGIPFEDSTPVFT PEIYVPEQDTFYKQNPNSIVRAYHSISLLLPDGRVFNGGGGLCGDCTTNHFDAQI FTPNYLYDSNGNLATRPKITRTSTQSVKVGGRITISTDSSITKASLIRYGTATHT VNTDQRRIPLTLTNNGGNSYSFQVPSDSGVALPGYWMLFVMNSAGVPSVASTIRV TQAAA 227 GOh2099 atgggcagcagccatcatcatcatcatcacagcagcggcctggtgccgcgcggca gccatatgggtaccgcctctgcccctatcggctcagccatcccgcgcaataactg ggccgtaacgtgcgacagcgcgaatagcggcaacgagtgcaataaagccatcgac ggcaataaagacaccttctggcacacgttttatggcgcaaatggcgacccgaagc caccgcatacctataccattgacatgaaaaccacccagaatgtgaacgggctgtc cgtgctgccgcgccaggacggcaatcagaacggatggatcggccgtcacgaggta tatttaagctccgacggcaccaactggggatccccggtcgcgtcgggcagctggt tcgccgacagcaccaccaagtattccaattttgaaacccgtcctgcacgctacgt gcgcttagtggccgtgacagaggcgaacggccagccatggacctcaatcgccgaa atcaatgtattccaagccagctcctataccgcgccgcagccaggacttgggcgtt ggggcccgaccatcgacctgcctatcgtacccgcagccgcggcgattgaaccaac gtcaggccgcgtactgatgtggagcagctaccgtaacgacgcggcggaaggcagc ccgggcggcatcactctgacgtcgagttgggatccatccacgggcatcgtctccg accgcaccgtgaccgtcacgaaacacgacatgttttgcccggggatcagcatgga cggcaacggccagatcgtcgtcacgggcggctgggacgccaagaagacgagcctc tatgacagtagcagcgacagttggatcccggggccggacatgcaggtggcacgcg ggtaccagtccagcgcgaccatgtcagacggccgtgtctttacaatcggcggctc atttagtggcggagtgtttgagaagaatggcgaagtctatagcccctcatccaaa acgtggacgtcacttccgaacgcgaaggtgaatcccatgttaaccgccgacaaac agggcctgtacatgagcgacaaccatgcgtggctgttcggctggaagaaggggag cgtctttcaggcgggcccgtcgaccgcaatgaattggtattacacgtcaggaagc ggggacgtgaaatcagccggcaagcgccagtcgaaccgcggcgtggcgccggacg caatgtgcggcaatgccgtgatgtatgacgcggtcaaaggcaagatcctgacatt tggcgggagtccggactacaccgacagtgacgcgacaaccaatgcccacattatt acccttggggagccggggacgagcccgaacacggtcttcgcgtccaatggcctct atttcgcgcgtacctttcatacgtcggtggtcctgccggacggatcaacctttat caccggcggacagcgccgtggcatccccttcgaagactcgacccccgtctttaca ccggagatttatgtgccggaacaggacacgttttataaacagaatccgaactcga ttgtacgcgcgtatcactccatcagccttcttctcccggacggacgtgtctttaa tggcggaggaggactgtgcggggactgcacgaccaatcattttgacgcgcagatc tttaccccgaattatctgtatgattcaaatgggaatctcgcgacccgtccgaaaa ttacccgtacatcaacccagtccgtcaaagtgggcggccgcattacgatcagtac cgacagcagcattaccaaagcgtcactgattcgttacggcaccgcaacccataca gtcaacacggaccagcgccgtattccgttaaccctgaccaataacggtggcaatt cgtatagcttccaggtaccgtcggactcgggcgtggcgctgccaggatactggat gctgtttgtgatgaatagcgcgggcgtcccgagcgtagcgagcacgatccgtgtg acccaggccgcagcttgataa 228 GOh2099 MGSSHHHHHHSSGLVPRGSHMGTASAPIGSAIPRNNWAVTCDSANSGNECNKAID GNKDTFWHTFYGANGDPKPPHTYTIDMKTTQNVNGLSVLPRQDGNQNGWIGRHEV YLSSDGTNWGSPVASGSWFADSTTKYSNFETRPARYVRLVAVTEANGQPWTSIAE INVFQASSYTAPQPGLGRWGPTIDLPIVPAAAAIEPTSGRVLMWSSYRNDAAEGS PGGITLTSSWDPSTGIVSDRTVTVTKHDMFCPGISMDGNGQIVVTGGWDAKKTSL YDSSSDSWIPGPDMQVARGYQSSATMSDGRVFTIGGSFSGGVFEKNGEVYSPSSK TWTSLPNAKVNPMLTADKQGLYMSDNHAWLFGWKKGSVFQAGPSTAMNWYYTSGS GDVKSAGKRQSNRGVAPDAMCGNAVMYDAVKGKILTFGGSPDYTDSDATTNAHII TLGEPGTSPNTVFASNGLYFARTFHTSVVLPDGSTFITGGQRRGIPFEDSTPVFT PEIYVPEQDTFYKQNPNSIVRAYHSISLLLPDGRVFNGGGGLCGDCTTNHFDAQI FTPNYLYDSNGNLATRPKITRTSTQSVKVGGRITISTDSSITKASLIRYGTATHT VNTDQRRIPLTLTNNGGNSYSFQVPSDSGVALPGYWMLFVMNSAGVPSVASTIRV TQAAA 229 GOh2100 atgggcagcagccatcatcatcatcatcacagcagcggcctggtgccgcgcggca gccatatgggtaccgcctctgcccctatcggctcagccatcccgcgcaataactg ggccgtaacgtgcgacagcgcgcagagcggcaacaaatgcaataaagccatcgac ggcaataaagacaccttctggcacacgttttatggcgcaaatggcgacccgaagc caccgcatacctataccattgacatgaaaaccacccagaatgtgaacgggctgtc cgtgctgccgcgccaggacggcaatcagaacggatggatcggccgtcacgaggta tatttaagctccgacggcaccaactggggatccccggtcgcgtcgggcagctggt tcgccgacagcaccaccaagtattccaattttgaaacccgtcctgcacgctacgt gcgcttagtggccgtgacagaggcgaacggccagccatggacctcaatcgccgaa atcaatgtattccaagccagctcctataccgcgccgcagccaggacttgggcgtt ggggcccgaccatcgacctgcctatcgtacccgcagccgcggcgattgaaccaac gtcaggccgcgtactgatgtggagcagctaccgtaacgacgcggcggaaggcagc ccgggcggcatcactctgacgtcgagttgggatccatccacgggcatcgtctccg accgcaccgtgaccgtcacgaaacacgacatgttttgcccggggatcagcatgga cggcaacggccagatcgtcgtcacgggcggctgggacgccaagaagacgagcctc tatgacagtagcagcgacagttggatcccggggccggacatgcaggtggcacgcg ggtaccagtccagcgcgaccatgtcagacggccgtgtctttacaatcggcggctc atttagtggcggagtgtttgagaagaatggcgaagtctatagcccctcatccaaa acgtggacgtcacttccgaacgcgaaggtgaatcccatgttaaccgccgacaaac agggcctgtacatgagcgacaaccatgcgtggctgttcggctggaagaaggggag cgtctttcaggcgggcccgtcgaccgcaatgaattggtattacacgtcaggaagc ggggacgtgaaatcagccggcaagcgccagtcgaaccgcggcgtggcgccggacg caatgtgcggcaatgccgtgatgtatgacgcggtcaaaggcaagatcctgacatt tggcgggagtccggactacaccgacagtgacgcgacaaccaatgcccacattatt acccttggggagccggggacgagcccgaacacggtcttcgcgtccaatggcctct atttcgcgcgtacctttcatacgtcggtggtcctgccggacggatcaacctttat caccggcggacagcgccgtggcatccccttcgaagactcgacccccgtctttaca ccggagatttatgtgccggaacaggacacgttttataaacagaatccgaactcga ttgtacgcgcgtatcactccatcagccttcttctcccggacggacgtgtctttaa tggcggaggaggactgtgcggggactgcacgaccaatcattttgacgcgcagatc tttaccccgaattatctgtatgattcaaatgggaatctcgcgacccgtccgaaaa ttacccgtacatcaacccagtccgtcaaagtgggcggccgcattacgatcagtac cgacagcagcattaccaaagcgtcactgattcgttacggcaccgcaacccataca gtcaacacggaccagcgccgtattccgttaaccctgaccaataacggtggcaatt cgtatagcttccaggtaccgtcggactcgggcgtggcgctgccaggatactggat gctgtttgtgatgaatagcgcgggcgtcccgagcgtagcgagcacgatccgtgtg acccaggccgcagcttgataa 230 GOh2100 MGSSHHHHHHSSGLVPRGSHMGTASAPIGSAIPRNNWAVTCDSAQSGNKCNKAID GNKDTFWHTFYGANGDPKPPHTYTIDMKTTQNVNGLSVLPRQDGNQNGWIGRHEV YLSSDGTNWGSPVASGSWFADSTTKYSNFETRPARYVRLVAVTEANGQPWTSIAE INVFQASSYTAPQPGLGRWGPTIDLPIVPAAAAIEPTSGRVLMWSSYRNDAAEGS PGGITLTSSWDPSTGIVSDRTVTVTKHDMFCPGISMDGNGQIVVTGGWDAKKTSL YDSSSDSWIPGPDMQVARGYQSSATMSDGRVFTIGGSFSGGVFEKNGEVYSPSSK TWTSLPNAKVNPMLTADKQGLYMSDNHAWLFGWKKGSVFQAGPSTAMNWYYTSGS GDVKSAGKRQSNRGVAPDAMCGNAVMYDAVKGKILTFGGSPDYTDSDATTNAHII TLGEPGTSPNTVFASNGLYFARTFHTSVVLPDGSTFITGGQRRGIPFEDSTPVFT PEIYVPEQDTFYKQNPNSIVRAYHSISLLLPDGRVFNGGGGLCGDCTTNHFDAQI FTPNYLYDSNGNLATRPKITRTSTQSVKVGGRITISTDSSITKASLIRYGTATHT VNTDQRRIPLTLTNNGGNSYSFQVPSDSGVALPGYWMLFVMNSAGVPSVASTIRV TQAAA 231 GOh2101 atgggcagcagccatcatcatcatcatcacagcagcggcctggtgccgcgcggca gccatatgggtaccgcctctgcccctatcggctcagccatcccgcgcaataactg ggccgtaacgtgcgacagcgcgcagagcggcaacgagtgcaataaagccatcgac ggcaataaagacaccttctggcacacgttttatggcgcagatggcgacccgaagc caccgcatacctataccattgacatgaaaaccacccagaatgtgaacgggctgtc cgtgctgccgcgccaggacggcaatcagaacggatggatcggccgtcacgaggta tatttaagctccgacggcaccaactggggatccccggtcgcgtcgggcagctggt tcgccgacagcaccaccaagtattccaattttgaaacccgtcctgcacgctacgt gcgcttagtggccgtgacagaggcgaacggccagccatggacctcaatcgccgaa atcaatgtattccaagccagctcctataccgcgccgcagccaggacttgggcgtt ggggcccgaccatcgacctgcctatcgtacccgcagccgcggcgattgaaccaac gtcaggccgcgtactgatgtggagcagctaccgtaacgacgcggcggaaggcagc ccgggcggcatcactctgacgtcgagttgggatccatccacgggcatcgtctccg accgcaccgtgaccgtcacgaaacacgacatgttttgcccggggatcagcatgga cggcaacggccagatcgtcgtcacgggcggctgggacgccaagaagacgagcctc tatgacagtagcagcgacagttggatcccggggccggacatgcaggtggcacgcg ggtaccagtccagcgcgaccatgtcagacggccgtgtctttacaatcggcggctc atttagtggcggagtgtttgagaagaatggcgaagtctatagcccctcatccaaa acgtggacgtcacttccgaacgcgaaggtgaatcccatgttaaccgccgacaaac agggcctgtacatgagcgacaaccatgcgtggctgttcggctggaagaaggggag cgtctttcaggcgggcccgtcgaccgcaatgaattggtattacacgtcaggaagc ggggacgtgaaatcagccggcaagcgccagtcgaaccgcggcgtggcgccggacg caatgtgcggcaatgccgtgatgtatgacgcggtcaaaggcaagatcctgacatt tggcgggagtccggactacaccgacagtgacgcgacaaccaatgcccacattatt acccttggggagccggggacgagcccgaacacggtcttcgcgtccaatggcctct atttcgcgcgtacctttcatacgtcggtggtcctgccggacggatcaacctttat caccggcggacagcgccgtggcatccccttcgaagactcgacccccgtctttaca ccggagatttatgtgccggaacaggacacgttttataaacagaatccgaactcga ttgtacgcgcgtatcactccatcagccttcttctcccggacggacgtgtctttaa tggcggaggaggactgtgcggggactgcacgaccaatcattttgacgcgcagatc tttaccccgaattatctgtatgattcaaatgggaatctcgcgacccgtccgaaaa ttacccgtacatcaacccagtccgtcaaagtgggcggccgcattacgatcagtac cgacagcagcattaccaaagcgtcactgattcgttacggcaccgcaacccataca gtcaacacggaccagcgccgtattccgttaaccctgaccaataacggtggcaatt cgtatagcttccaggtaccgtcggactcgggcgtggcgctgccaggatactggat gctgtttgtgatgaatagcgcgggcgtcccgagcgtagcgagcacgatccgtgtg acccaggccgcagcttgataa 232 GOh2101 MGSSHHHHHHSSGLVPRGSHMGTASAPIGSAIPRNNWAVTCDSAQSGNECNKAID GNKDTFWHTFYGADGDPKPPHTYTIDMKTTQNVNGLSVLPRQDGNQNGWIGRHEV YLSSDGTNWGSPVASGSWFADSTTKYSNFETRPARYVRLVAVTEANGQPWTSIAE INVFQASSYTAPQPGLGRWGPTIDLPIVPAAAAIEPTSGRVLMWSSYRNDAAEGS PGGITLTSSWDPSTGIVSDRTVTVTKHDMFCPGISMDGNGQIVVTGGWDAKKTSL YDSSSDSWIPGPDMQVARGYQSSATMSDGRVFTIGGSFSGGVFEKNGEVYSPSSK TWTSLPNAKVNPMLTADKQGLYMSDNHAWLFGWKKGSVFQAGPSTAMNWYYTSGS GDVKSAGKRQSNRGVAPDAMCGNAVMYDAVKGKILTFGGSPDYTDSDATTNAHII TLGEPGTSPNTVFASNGLYFARTFHTSVVLPDGSTFITGGQRRGIPFEDSTPVFT PEIYVPEQDTFYKQNPNSIVRAYHSISLLLPDGRVFNGGGGLCGDCTTNHFDAQI FTPNYLYDSNGNLATRPKITRTSTQSVKVGGRITISTDSSITKASLIRYGTATHT VNTDQRRIPLTLTNNGGNSYSFQVPSDSGVALPGYWMLFVMNSAGVPSVASTIRV TQAAA 233 GOh2102 atgggcagcagccatcatcatcatcatcacagcagcggcctggtgccgcgcggca gccatatgggtaccgcctctgcccctatcggctcagccatcccgcgcaataactg ggccgtaacgtgcgacagcgcgcagagcggcaacgagtgcaataaagccatcgac ggcaataaagacaccttctggcacacgttttatggcgcagaaggcgacccgaagc caccgcatacctataccattgacatgaaaaccacccagaatgtgaacgggctgtc cgtgctgccgcgccaggacggcaatcagaacggatggatcggccgtcacgaggta tatttaagctccgacggcaccaactggggatccccggtcgcgtcgggcagctggt tcgccgacagcaccaccaagtattccaattttgaaacccgtcctgcacgctacgt gcgcttagtggccgtgacagaggcgaacggccagccatggacctcaatcgccgaa atcaatgtattccaagccagctcctataccgcgccgcagccaggacttgggcgtt ggggcccgaccatcgacctgcctatcgtacccgcagccgcggcgattgaaccaac gtcaggccgcgtactgatgtggagcagctaccgtaacgacgcggcggaaggcagc ccgggcggcatcactctgacgtcgagttgggatccatccacgggcatcgtctccg accgcaccgtgaccgtcacgaaacacgacatgttttgcccggggatcagcatgga cggcaacggccagatcgtcgtcacgggcggctgggacgccaagaagacgagcctc tatgacagtagcagcgacagttggatcccggggccggacatgcaggtggcacgcg ggtaccagtccagcgcgaccatgtcagacggccgtgtctttacaatcggcggctc atttagtggcggagtgtttgagaagaatggcgaagtctatagcccctcatccaaa acgtggacgtcacttccgaacgcgaaggtgaatcccatgttaaccgccgacaaac agggcctgtacatgagcgacaaccatgcgtggctgttcggctggaagaaggggag cgtctttcaggcgggcccgtcgaccgcaatgaattggtattacacgtcaggaagc ggggacgtgaaatcagccggcaagcgccagtcgaaccgcggcgtggcgccggacg caatgtgcggcaatgccgtgatgtatgacgcggtcaaaggcaagatcctgacatt tggcgggagtccggactacaccgacagtgacgcgacaaccaatgcccacattatt acccttggggagccggggacgagcccgaacacggtcttcgcgtccaatggcctct atttcgcgcgtacctttcatacgtcggtggtcctgccggacggatcaacctttat caccggcggacagcgccgtggcatccccttcgaagactcgacccccgtctttaca ccggagatttatgtgccggaacaggacacgttttataaacagaatccgaactcga ttgtacgcgcgtatcactccatcagccttcttctcccggacggacgtgtctttaa tggcggaggaggactgtgcggggactgcacgaccaatcattttgacgcgcagatc tttaccccgaattatctgtatgattcaaatgggaatctcgcgacccgtccgaaaa ttacccgtacatcaacccagtccgtcaaagtgggcggccgcattacgatcagtac cgacagcagcattaccaaagcgtcactgattcgttacggcaccgcaacccataca gtcaacacggaccagcgccgtattccgttaaccctgaccaataacggtggcaatt cgtatagcttccaggtaccgtcggactcgggcgtggcgctgccaggatactggat gctgtttgtgatgaatagcgcgggcgtcccgagcgtagcgagcacgatccgtgtg acccaggccgcagcttgataa 234 GOh2102 MGSSHHHHHHSSGLVPRGSHMGTASAPIGSAIPRNNWAVTCDSAQSGNECNKAID GNKDTFWHTFYGAEGDPKPPHTYTIDMKTTQNVNGLSVLPRQDGNQNGWIGRHEV YLSSDGTNWGSPVASGSWFADSTTKYSNFETRPARYVRLVAVTEANGQPWTSIAE INVFQASSYTAPQPGLGRWGPTIDLPIVPAAAAIEPTSGRVLMWSSYRNDAAEGS PGGITLTSSWDPSTGIVSDRTVTVTKHDMFCPGISMDGNGQIVVTGGWDAKKTSL YDSSSDSWIPGPDMQVARGYQSSATMSDGRVFTIGGSFSGGVFEKNGEVYSPSSK TWTSLPNAKVNPMLTADKQGLYMSDNHAWLFGWKKGSVFQAGPSTAMNWYYTSGS GDVKSAGKRQSNRGVAPDAMCGNAVMYDAVKGKILTFGGSPDYTDSDATTNAHII TLGEPGTSPNTVFASNGLYFARTFHTSVVLPDGSTFITGGQRRGIPFEDSTPVFT PEIYVPEQDTFYKQNPNSIVRAYHSISLLLPDGRVFNGGGGLCGDCTTNHFDAQI FTPNYLYDSNGNLATRPKITRTSTQSVKVGGRITISTDSSITKASLIRYGTATHT VNTDQRRIPLTLTNNGGNSYSFQVPSDSGVALPGYWMLFVMNSAGVPSVASTIRV TQAAA 235 GOh2103 atgggcagcagccatcatcatcatcatcacagcagcggcctggtgccgcgcggca gccatatgggtaccgcctctgcccctatcggctcagccatcccgcgcaataactg ggccgtaacgtgcgacagcgcgcagagcggcaacgagtgcaataaagccatcgac ggcaataaagacaccttctggcacacgttttatggcgcatttggcgacccgaagc caccgcatacctataccattgacatgaaaaccacccagaatgtgaacgggctgtc cgtgctgccgcgccaggacggcaatcagaacggatggatcggccgtcacgaggta tatttaagctccgacggcaccaactggggatccccggtcgcgtcgggcagctggt tcgccgacagcaccaccaagtattccaattttgaaacccgtcctgcacgctacgt gcgcttagtggccgtgacagaggcgaacggccagccatggacctcaatcgccgaa atcaatgtattccaagccagctcctataccgcgccgcagccaggacttgggcgtt ggggcccgaccatcgacctgcctatcgtacccgcagccgcggcgattgaaccaac gtcaggccgcgtactgatgtggagcagctaccgtaacgacgcggcggaaggcagc ccgggcggcatcactctgacgtcgagttgggatccatccacgggcatcgtctccg accgcaccgtgaccgtcacgaaacacgacatgttttgcccggggatcagcatgga cggcaacggccagatcgtcgtcacgggcggctgggacgccaagaagacgagcctc tatgacagtagcagcgacagttggatcccggggccggacatgcaggtggcacgcg ggtaccagtccagcgcgaccatgtcagacggccgtgtctttacaatcggcggctc atttagtggcggagtgtttgagaagaatggcgaagtctatagcccctcatccaaa acgtggacgtcacttccgaacgcgaaggtgaatcccatgttaaccgccgacaaac agggcctgtacatgagcgacaaccatgcgtggctgttcggctggaagaaggggag cgtctttcaggcgggcccgtcgaccgcaatgaattggtattacacgtcaggaagc ggggacgtgaaatcagccggcaagcgccagtcgaaccgcggcgtggcgccggacg caatgtgcggcaatgccgtgatgtatgacgcggtcaaaggcaagatcctgacatt tggcgggagtccggactacaccgacagtgacgcgacaaccaatgcccacattatt acccttggggagccggggacgagcccgaacacggtcttcgcgtccaatggcctct atttcgcgcgtacctttcatacgtcggtggtcctgccggacggatcaacctttat caccggcggacagcgccgtggcatccccttcgaagactcgacccccgtctttaca ccggagatttatgtgccggaacaggacacgttttataaacagaatccgaactcga ttgtacgcgcgtatcactccatcagccttcttctcccggacggacgtgtctttaa tggcggaggaggactgtgcggggactgcacgaccaatcattttgacgcgcagatc tttaccccgaattatctgtatgattcaaatgggaatctcgcgacccgtccgaaaa ttacccgtacatcaacccagtccgtcaaagtgggcggccgcattacgatcagtac cgacagcagcattaccaaagcgtcactgattcgttacggcaccgcaacccataca gtcaacacggaccagcgccgtattccgttaaccctgaccaataacggtggcaatt cgtatagcttccaggtaccgtcggactcgggcgtggcgctgccaggatactggat gctgtttgtgatgaatagcgcgggcgtcccgagcgtagcgagcacgatccgtgtg acccaggccgcagcttgataa 236 GOh2103 MGSSHHHHHHSSGLVPRGSHMGTASAPIGSAIPRNNWAVTCDSAQSGNECNKAID GNKDTFWHTFYGAFGDPKPPHTYTIDMKTTQNVNGLSVLPRQDGNQNGWIGRHEV YLSSDGTNWGSPVASGSWFADSTTKYSNFETRPARYVRLVAVTEANGQPWTSIAE INVFQASSYTAPQPGLGRWGPTIDLPIVPAAAAIEPTSGRVLMWSSYRNDAAEGS PGGITLTSSWDPSTGIVSDRTVTVTKHDMFCPGISMDGNGQIVVTGGWDAKKTSL YDSSSDSWIPGPDMQVARGYQSSATMSDGRVFTIGGSFSGGVFEKNGEVYSPSSK TWTSLPNAKVNPMLTADKQGLYMSDNHAWLFGWKKGSVFQAGPSTAMNWYYTSGS GDVKSAGKRQSNRGVAPDAMCGNAVMYDAVKGKILTFGGSPDYTDSDATTNAHII TLGEPGTSPNTVFASNGLYFARTFHTSVVLPDGSTFITGGQRRGIPFEDSTPVFT PEIYVPEQDTFYKQNPNSIVRAYHSISLLLPDGRVFNGGGGLCGDCTTNHFDAQI FTPNYLYDSNGNLATRPKITRTSTQSVKVGGRITISTDSSITKASLIRYGTATHT VNTDQRRIPLTLTNNGGNSYSFQVPSDSGVALPGYWMLFVMNSAGVPSVASTIRV TQAAA 237 GOh2104 atgggcagcagccatcatcatcatcatcacagcagcggcctggtgccgcgcggca gccatatgggtaccgcctctgcccctatcggctcagccatcccgcgcaataactg ggccgtaacgtgcgacagcgcgcagagcggcaacgagtgcaataaagccatcgac ggcaataaagacaccttctggcacacgttttatggcgcacatggcgacccgaagc caccgcatacctataccattgacatgaaaaccacccagaatgtgaacgggctgtc cgtgctgccgcgccaggacggcaatcagaacggatggatcggccgtcacgaggta tatttaagctccgacggcaccaactggggatccccggtcgcgtcgggcagctggt tcgccgacagcaccaccaagtattccaattttgaaacccgtcctgcacgctacgt gcgcttagtggccgtgacagaggcgaacggccagccatggacctcaatcgccgaa atcaatgtattccaagccagctcctataccgcgccgcagccaggacttgggcgtt ggggcccgaccatcgacctgcctatcgtacccgcagccgcggcgattgaaccaac gtcaggccgcgtactgatgtggagcagctaccgtaacgacgcggcggaaggcagc ccgggcggcatcactctgacgtcgagttgggatccatccacgggcatcgtctccg accgcaccgtgaccgtcacgaaacacgacatgttttgcccggggatcagcatgga cggcaacggccagatcgtcgtcacgggcggctgggacgccaagaagacgagcctc tatgacagtagcagcgacagttggatcccggggccggacatgcaggtggcacgcg ggtaccagtccagcgcgaccatgtcagacggccgtgtctttacaatcggcggctc atttagtggcggagtgtttgagaagaatggcgaagtctatagcccctcatccaaa acgtggacgtcacttccgaacgcgaaggtgaatcccatgttaaccgccgacaaac agggcctgtacatgagcgacaaccatgcgtggctgttcggctggaagaaggggag cgtctttcaggcgggcccgtcgaccgcaatgaattggtattacacgtcaggaagc ggggacgtgaaatcagccggcaagcgccagtcgaaccgcggcgtggcgccggacg caatgtgcggcaatgccgtgatgtatgacgcggtcaaaggcaagatcctgacatt tggcgggagtccggactacaccgacagtgacgcgacaaccaatgcccacattatt acccttggggagccggggacgagcccgaacacggtcttcgcgtccaatggcctct atttcgcgcgtacctttcatacgtcggtggtcctgccggacggatcaacctttat caccggcggacagcgccgtggcatccccttcgaagactcgacccccgtctttaca ccggagatttatgtgccggaacaggacacgttttataaacagaatccgaactcga ttgtacgcgcgtatcactccatcagccttcttctcccggacggacgtgtctttaa tggcggaggaggactgtgcggggactgcacgaccaatcattttgacgcgcagatc tttaccccgaattatctgtatgattcaaatgggaatctcgcgacccgtccgaaaa ttacccgtacatcaacccagtccgtcaaagtgggcggccgcattacgatcagtac cgacagcagcattaccaaagcgtcactgattcgttacggcaccgcaacccataca gtcaacacggaccagcgccgtattccgttaaccctgaccaataacggtggcaatt cgtatagcttccaggtaccgtcggactcgggcgtggcgctgccaggatactggat gctgtttgtgatgaatagcgcgggcgtcccgagcgtagcgagcacgatccgtgtg acccaggccgcagcttgataa 238 GOh2104 MGSSHHHHHHSSGLVPRGSHMGTASAPIGSAIPRNNWAVTCDSAQSGNECNKAID GNKDTFWHTFYGAHGDPKPPHTYTIDMKTTQNVNGLSVLPRQDGNQNGWIGRHEV YLSSDGTNWGSPVASGSWFADSTTKYSNFETRPARYVRLVAVTEANGQPWTSIAE INVFQASSYTAPQPGLGRWGPTIDLPIVPAAAAIEPTSGRVLMWSSYRNDAAEGS PGGITLTSSWDPSTGIVSDRTVTVTKHDMFCPGISMDGNGQIVVTGGWDAKKTSL YDSSSDSWIPGPDMQVARGYQSSATMSDGRVFTIGGSFSGGVFEKNGEVYSPSSK TWTSLPNAKVNPMLTADKQGLYMSDNHAWLFGWKKGSVFQAGPSTAMNWYYTSGS GDVKSAGKRQSNRGVAPDAMCGNAVMYDAVKGKILTFGGSPDYTDSDATTNAHII TLGEPGTSPNTVFASNGLYFARTFHTSVVLPDGSTFITGGQRRGIPFEDSTPVFT PEIYVPEQDTFYKQNPNSIVRAYHSISLLLPDGRVFNGGGGLCGDCTTNHFDAQI FTPNYLYDSNGNLATRPKITRTSTQSVKVGGRITISTDSSITKASLIRYGTATHT VNTDQRRIPLTLTNNGGNSYSFQVPSDSGVALPGYWMLFVMNSAGVPSVASTIRV TQAAA 239 GOh2105 atgggcagcagccatcatcatcatcatcacagcagcggcctggtgccgcgcggca gccatatgggtaccgcctctgcccctatcggctcagccatcccgcgcaataactg ggccgtaacgtgcgacagcgcgcagagcggcaacgagtgcaataaagccatcgac ggcaataaagacaccttctggcacacgttttatggcgcacttggcgacccgaagc caccgcatacctataccattgacatgaaaaccacccagaatgtgaacgggctgtc cgtgctgccgcgccaggacggcaatcagaacggatggatcggccgtcacgaggta tatttaagctccgacggcaccaactggggatccccggtcgcgtcgggcagctggt tcgccgacagcaccaccaagtattccaattttgaaacccgtcctgcacgctacgt gcgcttagtggccgtgacagaggcgaacggccagccatggacctcaatcgccgaa atcaatgtattccaagccagctcctataccgcgccgcagccaggacttgggcgtt ggggcccgaccatcgacctgcctatcgtacccgcagccgcggcgattgaaccaac gtcaggccgcgtactgatgtggagcagctaccgtaacgacgcggcggaaggcagc ccgggcggcatcactctgacgtcgagttgggatccatccacgggcatcgtctccg accgcaccgtgaccgtcacgaaacacgacatgttttgcccggggatcagcatgga cggcaacggccagatcgtcgtcacgggcggctgggacgccaagaagacgagcctc tatgacagtagcagcgacagttggatcccggggccggacatgcaggtggcacgcg ggtaccagtccagcgcgaccatgtcagacggccgtgtctttacaatcggcggctc atttagtggcggagtgtttgagaagaatggcgaagtctatagcccctcatccaaa acgtggacgtcacttccgaacgcgaaggtgaatcccatgttaaccgccgacaaac agggcctgtacatgagcgacaaccatgcgtggctgttcggctggaagaaggggag cgtctttcaggcgggcccgtcgaccgcaatgaattggtattacacgtcaggaagc ggggacgtgaaatcagccggcaagcgccagtcgaaccgcggcgtggcgccggacg caatgtgcggcaatgccgtgatgtatgacgcggtcaaaggcaagatcctgacatt tggcgggagtccggactacaccgacagtgacgcgacaaccaatgcccacattatt acccttggggagccggggacgagcccgaacacggtcttcgcgtccaatggcctct atttcgcgcgtacctttcatacgtcggtggtcctgccggacggatcaacctttat caccggcggacagcgccgtggcatccccttcgaagactcgacccccgtctttaca ccggagatttatgtgccggaacaggacacgttttataaacagaatccgaactcga ttgtacgcgcgtatcactccatcagccttcttctcccggacggacgtgtctttaa tggcggaggaggactgtgcggggactgcacgaccaatcattttgacgcgcagatc tttaccccgaattatctgtatgattcaaatgggaatctcgcgacccgtccgaaaa ttacccgtacatcaacccagtccgtcaaagtgggcggccgcattacgatcagtac cgacagcagcattaccaaagcgtcactgattcgttacggcaccgcaacccataca gtcaacacggaccagcgccgtattccgttaaccctgaccaataacggtggcaatt cgtatagcttccaggtaccgtcggactcgggcgtggcgctgccaggatactggat gctgtttgtgatgaatagcgcgggcgtcccgagcgtagcgagcacgatccgtgtg acccaggccgcagcttgataa 240 GOh2105 MGSSHHHHHHSSGLVPRGSHMGTASAPIGSAIPRNNWAVTCDSAQSGNECNKAID GNKDTFWHTFYGALGDPKPPHTYTIDMKTTQNVNGLSVLPRQDGNQNGWIGRHEV YLSSDGTNWGSPVASGSWFADSTTKYSNFETRPARYVRLVAVTEANGQPWTSIAE INVFQASSYTAPQPGLGRWGPTIDLPIVPAAAAIEPTSGRVLMWSSYRNDAAEGS PGGITLTSSWDPSTGIVSDRTVTVTKHDMFCPGISMDGNGQIVVTGGWDAKKTSL YDSSSDSWIPGPDMQVARGYQSSATMSDGRVFTIGGSFSGGVFEKNGEVYSPSSK TWTSLPNAKVNPMLTADKQGLYMSDNHAWLFGWKKGSVFQAGPSTAMNWYYTSGS GDVKSAGKRQSNRGVAPDAMCGNAVMYDAVKGKILTFGGSPDYTDSDATTNAHII TLGEPGTSPNTVFASNGLYFARTFHTSVVLPDGSTFITGGQRRGIPFEDSTPVFT PEIYVPEQDTFYKQNPNSIVRAYHSISLLLPDGRVFNGGGGLCGDCTTNHFDAQI FTPNYLYDSNGNLATRPKITRTSTQSVKVGGRITISTDSSITKASLIRYGTATHT VNTDQRRIPLTLTNNGGNSYSFQVPSDSGVALPGYWMLFVMNSAGVPSVASTIRV TQAAA 241 GOh2106 atgggcagcagccatcatcatcatcatcacagcagcggcctggtgccgcgcggca gccatatgggtaccgcctctgcccctatcggctcagccatcccgcgcaataactg ggccgtaacgtgcgacagcgcgcagagcggcaacgagtgcaataaagccatcgac ggcaataaagacaccttctggcacacgttttatggcgcaatgggcgacccgaagc caccgcatacctataccattgacatgaaaaccacccagaatgtgaacgggctgtc cgtgctgccgcgccaggacggcaatcagaacggatggatcggccgtcacgaggta tatttaagctccgacggcaccaactggggatccccggtcgcgtcgggcagctggt tcgccgacagcaccaccaagtattccaattttgaaacccgtcctgcacgctacgt gcgcttagtggccgtgacagaggcgaacggccagccatggacctcaatcgccgaa atcaatgtattccaagccagctcctataccgcgccgcagccaggacttgggcgtt ggggcccgaccatcgacctgcctatcgtacccgcagccgcggcgattgaaccaac gtcaggccgcgtactgatgtggagcagctaccgtaacgacgcggcggaaggcagc ccgggcggcatcactctgacgtcgagttgggatccatccacgggcatcgtctccg accgcaccgtgaccgtcacgaaacacgacatgttttgcccggggatcagcatgga cggcaacggccagatcgtcgtcacgggcggctgggacgccaagaagacgagcctc tatgacagtagcagcgacagttggatcccggggccggacatgcaggtggcacgcg ggtaccagtccagcgcgaccatgtcagacggccgtgtctttacaatcggcggctc atttagtggcggagtgtttgagaagaatggcgaagtctatagcccctcatccaaa acgtggacgtcacttccgaacgcgaaggtgaatcccatgttaaccgccgacaaac agggcctgtacatgagcgacaaccatgcgtggctgttcggctggaagaaggggag cgtctttcaggcgggcccgtcgaccgcaatgaattggtattacacgtcaggaagc ggggacgtgaaatcagccggcaagcgccagtcgaaccgcggcgtggcgccggacg caatgtgcggcaatgccgtgatgtatgacgcggtcaaaggcaagatcctgacatt tggcgggagtccggactacaccgacagtgacgcgacaaccaatgcccacattatt acccttggggagccggggacgagcccgaacacggtcttcgcgtccaatggcctct atttcgcgcgtacctttcatacgtcggtggtcctgccggacggatcaacctttat caccggcggacagcgccgtggcatccccttcgaagactcgacccccgtctttaca ccggagatttatgtgccggaacaggacacgttttataaacagaatccgaactcga ttgtacgcgcgtatcactccatcagccttcttctcccggacggacgtgtctttaa tggcggaggaggactgtgcggggactgcacgaccaatcattttgacgcgcagatc tttaccccgaattatctgtatgattcaaatgggaatctcgcgacccgtccgaaaa ttacccgtacatcaacccagtccgtcaaagtgggcggccgcattacgatcagtac cgacagcagcattaccaaagcgtcactgattcgttacggcaccgcaacccataca gtcaacacggaccagcgccgtattccgttaaccctgaccaataacggtggcaatt cgtatagcttccaggtaccgtcggactcgggcgtggcgctgccaggatactggat gctgtttgtgatgaatagcgcgggcgtcccgagcgtagcgagcacgatccgtgtg acccaggccgcagcttgataa 242 GOh2106 MGSSHHHHHHSSGLVPRGSHMGTASAPIGSAIPRNNWAVTCDSAQSGNECNKAID GNKDTFWHTFYGAMGDPKPPHTYTIDMKTTQNVNGLSVLPRQDGNQNGWIGRHEV YLSSDGTNWGSPVASGSWFADSTTKYSNFETRPARYVRLVAVTEANGQPWTSIAE INVFQASSYTAPQPGLGRWGPTIDLPIVPAAAAIEPTSGRVLMWSSYRNDAAEGS PGGITLTSSWDPSTGIVSDRTVTVTKHDMFCPGISMDGNGQIVVTGGWDAKKTSL YDSSSDSWIPGPDMQVARGYQSSATMSDGRVFTIGGSFSGGVFEKNGEVYSPSSK TWTSLPNAKVNPMLTADKQGLYMSDNHAWLFGWKKGSVFQAGPSTAMNWYYTSGS GDVKSAGKRQSNRGVAPDAMCGNAVMYDAVKGKILTFGGSPDYTDSDATTNAHII TLGEPGTSPNTVFASNGLYFARTFHTSVVLPDGSTFITGGQRRGIPFEDSTPVFT PEIYVPEQDTFYKQNPNSIVRAYHSISLLLPDGRVFNGGGGLCGDCTTNHFDAQI FTPNYLYDSNGNLATRPKITRTSTQSVKVGGRITISTDSSITKASLIRYGTATHT VNTDQRRIPLTLTNNGGNSYSFQVPSDSGVALPGYWMLFVMNSAGVPSVASTIRV TQAAA 243 GOh2107 atgggcagcagccatcatcatcatcatcacagcagcggcctggtgccgcgcggca gccatatgggtaccgcctctgcccctatcggctcagccatcccgcgcaataactg ggccgtaacgtgcgacagcgcgcagagcggcaacgagtgcaataaagccatcgac ggcaataaagacaccttctggcacacgttttatggcgcaacaggcgacccgaagc caccgcatacctataccattgacatgaaaaccacccagaatgtgaacgggctgtc cgtgctgccgcgccaggacggcaatcagaacggatggatcggccgtcacgaggta tatttaagctccgacggcaccaactggggatccccggtcgcgtcgggcagctggt tcgccgacagcaccaccaagtattccaattttgaaacccgtcctgcacgctacgt gcgcttagtggccgtgacagaggcgaacggccagccatggacctcaatcgccgaa atcaatgtattccaagccagctcctataccgcgccgcagccaggacttgggcgtt ggggcccgaccatcgacctgcctatcgtacccgcagccgcggcgattgaaccaac gtcaggccgcgtactgatgtggagcagctaccgtaacgacgcggcggaaggcagc ccgggcggcatcactctgacgtcgagttgggatccatccacgggcatcgtctccg accgcaccgtgaccgtcacgaaacacgacatgttttgcccggggatcagcatgga cggcaacggccagatcgtcgtcacgggcggctgggacgccaagaagacgagcctc tatgacagtagcagcgacagttggatcccggggccggacatgcaggtggcacgcg ggtaccagtccagcgcgaccatgtcagacggccgtgtctttacaatcggcggctc atttagtggcggagtgtttgagaagaatggcgaagtctatagcccctcatccaaa acgtggacgtcacttccgaacgcgaaggtgaatcccatgttaaccgccgacaaac agggcctgtacatgagcgacaaccatgcgtggctgttcggctggaagaaggggag cgtctttcaggcgggcccgtcgaccgcaatgaattggtattacacgtcaggaagc ggggacgtgaaatcagccggcaagcgccagtcgaaccgcggcgtggcgccggacg caatgtgcggcaatgccgtgatgtatgacgcggtcaaaggcaagatcctgacatt tggcgggagtccggactacaccgacagtgacgcgacaaccaatgcccacattatt acccttggggagccggggacgagcccgaacacggtcttcgcgtccaatggcctct atttcgcgcgtacctttcatacgtcggtggtcctgccggacggatcaacctttat caccggcggacagcgccgtggcatccccttcgaagactcgacccccgtctttaca ccggagatttatgtgccggaacaggacacgttttataaacagaatccgaactcga ttgtacgcgcgtatcactccatcagccttcttctcccggacggacgtgtctttaa tggcggaggaggactgtgcggggactgcacgaccaatcattttgacgcgcagatc tttaccccgaattatctgtatgattcaaatgggaatctcgcgacccgtccgaaaa ttacccgtacatcaacccagtccgtcaaagtgggcggccgcattacgatcagtac cgacagcagcattaccaaagcgtcactgattcgttacggcaccgcaacccataca gtcaacacggaccagcgccgtattccgttaaccctgaccaataacggtggcaatt cgtatagcttccaggtaccgtcggactcgggcgtggcgctgccaggatactggat gctgtttgtgatgaatagcgcgggcgtcccgagcgtagcgagcacgatccgtgtg acccaggccgcagcttgataa 244 GOh2107 MGSSHHHHHHSSGLVPRGSHMGTASAPIGSAIPRNNWAVTCDSAQSGNECNKAID GNKDTFWHTFYGATGDPKPPHTYTIDMKTTQNVNGLSVLPRQDGNQNGWIGRHEV YLSSDGTNWGSPVASGSWFADSTTKYSNFETRPARYVRLVAVTEANGQPWTSIAE INVFQASSYTAPQPGLGRWGPTIDLPIVPAAAAIEPTSGRVLMWSSYRNDAAEGS PGGITLTSSWDPSTGIVSDRTVTVTKHDMFCPGISMDGNGQIVVTGGWDAKKTSL YDSSSDSWIPGPDMQVARGYQSSATMSDGRVFTIGGSFSGGVFEKNGEVYSPSSK TWTSLPNAKVNPMLTADKQGLYMSDNHAWLFGWKKGSVFQAGPSTAMNWYYTSGS GDVKSAGKRQSNRGVAPDAMCGNAVMYDAVKGKILTFGGSPDYTDSDATTNAHII TLGEPGTSPNTVFASNGLYFARTFHTSVVLPDGSTFITGGQRRGIPFEDSTPVFT PEIYVPEQDTFYKQNPNSIVRAYHSISLLLPDGRVFNGGGGLCGDCTTNHFDAQI FTPNYLYDSNGNLATRPKITRTSTQSVKVGGRITISTDSSITKASLIRYGTATHT VNTDQRRIPLTLTNNGGNSYSFQVPSDSGVALPGYWMLFVMNSAGVPSVASTIRV TQAAA 245 GOh2108 atgggcagcagccatcatcatcatcatcacagcagcggcctggtgccgcgcggca gccatatgggtaccgcctctgcccctatcggctcagccatcccgcgcaataactg ggccgtaacgtgcgacagcgcgcagagcggcaacgagtgcaataaagccatcgac ggcaataaagacaccttctggcacacgttttatggcgcatggggcgacccgaagc caccgcatacctataccattgacatgaaaaccacccagaatgtgaacgggctgtc cgtgctgccgcgccaggacggcaatcagaacggatggatcggccgtcacgaggta tatttaagctccgacggcaccaactggggatccccggtcgcgtcgggcagctggt tcgccgacagcaccaccaagtattccaattttgaaacccgtcctgcacgctacgt gcgcttagtggccgtgacagaggcgaacggccagccatggacctcaatcgccgaa atcaatgtattccaagccagctcctataccgcgccgcagccaggacttgggcgtt ggggcccgaccatcgacctgcctatcgtacccgcagccgcggcgattgaaccaac gtcaggccgcgtactgatgtggagcagctaccgtaacgacgcggcggaaggcagc ccgggcggcatcactctgacgtcgagttgggatccatccacgggcatcgtctccg accgcaccgtgaccgtcacgaaacacgacatgttttgcccggggatcagcatgga cggcaacggccagatcgtcgtcacgggcggctgggacgccaagaagacgagcctc tatgacagtagcagcgacagttggatcccggggccggacatgcaggtggcacgcg ggtaccagtccagcgcgaccatgtcagacggccgtgtctttacaatcggcggctc atttagtggcggagtgtttgagaagaatggcgaagtctatagcccctcatccaaa acgtggacgtcacttccgaacgcgaaggtgaatcccatgttaaccgccgacaaac agggcctgtacatgagcgacaaccatgcgtggctgttcggctggaagaaggggag cgtctttcaggcgggcccgtcgaccgcaatgaattggtattacacgtcaggaagc ggggacgtgaaatcagccggcaagcgccagtcgaaccgcggcgtggcgccggacg caatgtgcggcaatgccgtgatgtatgacgcggtcaaaggcaagatcctgacatt tggcgggagtccggactacaccgacagtgacgcgacaaccaatgcccacattatt acccttggggagccggggacgagcccgaacacggtcttcgcgtccaatggcctct atttcgcgcgtacctttcatacgtcggtggtcctgccggacggatcaacctttat caccggcggacagcgccgtggcatccccttcgaagactcgacccccgtctttaca ccggagatttatgtgccggaacaggacacgttttataaacagaatccgaactcga ttgtacgcgcgtatcactccatcagccttcttctcccggacggacgtgtctttaa tggcggaggaggactgtgcggggactgcacgaccaatcattttgacgcgcagatc tttaccccgaattatctgtatgattcaaatgggaatctcgcgacccgtccgaaaa ttacccgtacatcaacccagtccgtcaaagtgggcggccgcattacgatcagtac cgacagcagcattaccaaagcgtcactgattcgttacggcaccgcaacccataca gtcaacacggaccagcgccgtattccgttaaccctgaccaataacggtggcaatt cgtatagcttccaggtaccgtcggactcgggcgtggcgctgccaggatactggat gctgtttgtgatgaatagcgcgggcgtcccgagcgtagcgagcacgatccgtgtg acccaggccgcagcttgataa 246 GOh2108 MGSSHHHHHHSSGLVPRGSHMGTASAPIGSAIPRNNWAVTCDSAQSGNECNKAID GNKDTFWHTFYGAWGDPKPPHTYTIDMKTTQNVNGLSVLPRQDGNQNGWIGRHEV YLSSDGTNWGSPVASGSWFADSTTKYSNFETRPARYVRLVAVTEANGQPWTSIAE INVFQASSYTAPQPGLGRWGPTIDLPIVPAAAAIEPTSGRVLMWSSYRNDAAEGS PGGITLTSSWDPSTGIVSDRTVTVTKHDMFCPGISMDGNGQIVVTGGWDAKKTSL YDSSSDSWIPGPDMQVARGYQSSATMSDGRVFTIGGSFSGGVFEKNGEVYSPSSK TWTSLPNAKVNPMLTADKQGLYMSDNHAWLFGWKKGSVFQAGPSTAMNWYYTSGS GDVKSAGKRQSNRGVAPDAMCGNAVMYDAVKGKILTFGGSPDYTDSDATTNAHII TLGEPGTSPNTVFASNGLYFARTFHTSVVLPDGSTFITGGQRRGIPFEDSTPVFT PEIYVPEQDTFYKQNPNSIVRAYHSISLLLPDGRVFNGGGGLCGDCTTNHFDAQI FTPNYLYDSNGNLATRPKITRTSTQSVKVGGRITISTDSSITKASLIRYGTATHT VNTDQRRIPLTLTNNGGNSYSFQVPSDSGVALPGYWMLFVMNSAGVPSVASTIRV TQAAA 247 GOh2109 atgggcagcagccatcatcatcatcatcacagcagcggcctggtgccgcgcggca gccatatgggtaccgcctctgcccctatcggctcagccatcccgcgcaataactg ggccgtaacgtgcgacagcgcgcagagcggcaacgagtgcaataaagccatcgac ggcaataaagacaccttctggcacacgttttatggcgcatatggcgacccgaagc caccgcatacctataccattgacatgaaaaccacccagaatgtgaacgggctgtc cgtgctgccgcgccaggacggcaatcagaacggatggatcggccgtcacgaggta tatttaagctccgacggcaccaactggggatccccggtcgcgtcgggcagctggt tcgccgacagcaccaccaagtattccaattttgaaacccgtcctgcacgctacgt gcgcttagtggccgtgacagaggcgaacggccagccatggacctcaatcgccgaa atcaatgtattccaagccagctcctataccgcgccgcagccaggacttgggcgtt ggggcccgaccatcgacctgcctatcgtacccgcagccgcggcgattgaaccaac gtcaggccgcgtactgatgtggagcagctaccgtaacgacgcggcggaaggcagc ccgggcggcatcactctgacgtcgagttgggatccatccacgggcatcgtctccg accgcaccgtgaccgtcacgaaacacgacatgttttgcccggggatcagcatgga cggcaacggccagatcgtcgtcacgggcggctgggacgccaagaagacgagcctc tatgacagtagcagcgacagttggatcccggggccggacatgcaggtggcacgcg ggtaccagtccagcgcgaccatgtcagacggccgtgtctttacaatcggcggctc atttagtggcggagtgtttgagaagaatggcgaagtctatagcccctcatccaaa acgtggacgtcacttccgaacgcgaaggtgaatcccatgttaaccgccgacaaac agggcctgtacatgagcgacaaccatgcgtggctgttcggctggaagaaggggag cgtctttcaggcgggcccgtcgaccgcaatgaattggtattacacgtcaggaagc ggggacgtgaaatcagccggcaagcgccagtcgaaccgcggcgtggcgccggacg caatgtgcggcaatgccgtgatgtatgacgcggtcaaaggcaagatcctgacatt tggcgggagtccggactacaccgacagtgacgcgacaaccaatgcccacattatt acccttggggagccggggacgagcccgaacacggtcttcgcgtccaatggcctct atttcgcgcgtacctttcatacgtcggtggtcctgccggacggatcaacctttat caccggcggacagcgccgtggcatccccttcgaagactcgacccccgtctttaca ccggagatttatgtgccggaacaggacacgttttataaacagaatccgaactcga ttgtacgcgcgtatcactccatcagccttcttctcccggacggacgtgtctttaa tggcggaggaggactgtgcggggactgcacgaccaatcattttgacgcgcagatc tttaccccgaattatctgtatgattcaaatgggaatctcgcgacccgtccgaaaa ttacccgtacatcaacccagtccgtcaaagtgggcggccgcattacgatcagtac cgacagcagcattaccaaagcgtcactgattcgttacggcaccgcaacccataca gtcaacacggaccagcgccgtattccgttaaccctgaccaataacggtggcaatt cgtatagcttccaggtaccgtcggactcgggcgtggcgctgccaggatactggat gctgtttgtgatgaatagcgcgggcgtcccgagcgtagcgagcacgatccgtgtg acccaggccgcagcttgataa 248 GOh2109 MGSSHHHHHHSSGLVPRGSHMGTASAPIGSAIPRNNWAVTCDSAQSGNECNKAID GNKDTFWHTFYGAYGDPKPPHTYTIDMKTTQNVNGLSVLPRQDGNQNGWIGRHEV YLSSDGTNWGSPVASGSWFADSTTKYSNFETRPARYVRLVAVTEANGQPWTSIAE INVFQASSYTAPQPGLGRWGPTIDLPIVPAAAAIEPTSGRVLMWSSYRNDAAEGS PGGITLTSSWDPSTGIVSDRTVTVTKHDMFCPGISMDGNGQIVVTGGWDAKKTSL YDSSSDSWIPGPDMQVARGYQSSATMSDGRVFTIGGSFSGGVFEKNGEVYSPSSK TWTSLPNAKVNPMLTADKQGLYMSDNHAWLFGWKKGSVFQAGPSTAMNWYYTSGS GDVKSAGKRQSNRGVAPDAMCGNAVMYDAVKGKILTFGGSPDYTDSDATTNAHII TLGEPGTSPNTVFASNGLYFARTFHTSVVLPDGSTFITGGQRRGIPFEDSTPVFT PEIYVPEQDTFYKQNPNSIVRAYHSISLLLPDGRVFNGGGGLCGDCTTNHFDAQI FTPNYLYDSNGNLATRPKITRTSTQSVKVGGRITISTDSSITKASLIRYGTATHT VNTDQRRIPLTLTNNGGNSYSFQVPSDSGVALPGYWMLFVMNSAGVPSVASTIRV TQAAA 249 GOh2110 atgggcagcagccatcatcatcatcatcacagcagcggcctggtgccgcgcggca gccatatgggtaccgcctctgcccctatcggctcagccatcccgcgcaataactg ggccgtaacgtgcgacagcgcgcagagcggcaacgagtgcaataaagccatcgac ggcaataaagacaccttctggcacacgttttatggcgcaaatggcgacccgaagc caccgcatacctataccattgacatgaaaaccacccagaatgtgaacgggctgtc cgtgctgccgcgccaggacggcaatcagaacggaggtatcggccgtcacgaggta tatttaagctccgacggcaccaactggggatccccggtcgcgtcgggcagctggt tcgccgacagcaccaccaagtattccaattttgaaacccgtcctgcacgctacgt gcgcttagtggccgtgacagaggcgaacggccagccatggacctcaatcgccgaa atcaatgtattccaagccagctcctataccgcgccgcagccaggacttgggcgtt ggggcccgaccatcgacctgcctatcgtacccgcagccgcggcgattgaaccaac gtcaggccgcgtactgatgtggagcagctaccgtaacgacgcggcggaaggcagc ccgggcggcatcactctgacgtcgagttgggatccatccacgggcatcgtctccg accgcaccgtgaccgtcacgaaacacgacatgttttgcccggggatcagcatgga cggcaacggccagatcgtcgtcacgggcggctgggacgccaagaagacgagcctc tatgacagtagcagcgacagttggatcccggggccggacatgcaggtggcacgcg ggtaccagtccagcgcgaccatgtcagacggccgtgtctttacaatcggcggctc atttagtggcggagtgtttgagaagaatggcgaagtctatagcccctcatccaaa acgtggacgtcacttccgaacgcgaaggtgaatcccatgttaaccgccgacaaac agggcctgtacatgagcgacaaccatgcgtggctgttcggctggaagaaggggag cgtctttcaggcgggcccgtcgaccgcaatgaattggtattacacgtcaggaagc ggggacgtgaaatcagccggcaagcgccagtcgaaccgcggcgtggcgccggacg caatgtgcggcaatgccgtgatgtatgacgcggtcaaaggcaagatcctgacatt tggcgggagtccggactacaccgacagtgacgcgacaaccaatgcccacattatt acccttggggagccggggacgagcccgaacacggtcttcgcgtccaatggcctct atttcgcgcgtacctttcatacgtcggtggtcctgccggacggatcaacctttat caccggcggacagcgccgtggcatccccttcgaagactcgacccccgtctttaca ccggagatttatgtgccggaacaggacacgttttataaacagaatccgaactcga ttgtacgcgcgtatcactccatcagccttcttctcccggacggacgtgtctttaa tggcggaggaggactgtgcggggactgcacgaccaatcattttgacgcgcagatc tttaccccgaattatctgtatgattcaaatgggaatctcgcgacccgtccgaaaa ttacccgtacatcaacccagtccgtcaaagtgggcggccgcattacgatcagtac cgacagcagcattaccaaagcgtcactgattcgttacggcaccgcaacccataca gtcaacacggaccagcgccgtattccgttaaccctgaccaataacggtggcaatt cgtatagcttccaggtaccgtcggactcgggcgtggcgctgccaggatactggat gctgtttgtgatgaatagcgcgggcgtcccgagcgtagcgagcacgatccgtgtg acccaggccgcagcttgataa 250 GOh2110 MGSSHHHHHHSSGLVPRGSHMGTASAPIGSAIPRNNWAVTCDSAQSGNECNKAID GNKDTFWHTFYGANGDPKPPHTYTIDMKTTQNVNGLSVLPRQDGNQNGGIGRHEV YLSSDGTNWGSPVASGSWFADSTTKYSNFETRPARYVRLVAVTEANGQPWTSIAE INVFQASSYTAPQPGLGRWGPTIDLPIVPAAAAIEPTSGRVLMWSSYRNDAAEGS PGGITLTSSWDPSTGIVSDRTVTVTKHDMFCPGISMDGNGQIVVTGGWDAKKTSL YDSSSDSWIPGPDMQVARGYQSSATMSDGRVFTIGGSFSGGVFEKNGEVYSPSSK TWTSLPNAKVNPMLTADKQGLYMSDNHAWLFGWKKGSVFQAGPSTAMNWYYTSGS GDVKSAGKRQSNRGVAPDAMCGNAVMYDAVKGKILTFGGSPDYTDSDATTNAHII TLGEPGTSPNTVFASNGLYFARTFHTSVVLPDGSTFITGGQRRGIPFEDSTPVFT PEIYVPEQDTFYKQNPNSIVRAYHSISLLLPDGRVFNGGGGLCGDCTTNHFDAQI FTPNYLYDSNGNLATRPKITRTSTQSVKVGGRITISTDSSITKASLIRYGTATHT VNTDQRRIPLTLTNNGGNSYSFQVPSDSGVALPGYWMLFVMNSAGVPSVASTIRV TQAAA 251 GOh2111 atgggcagcagccatcatcatcatcatcacagcagcggcctggtgccgcgcggca gccatatgggtaccgcctctgcccctatcggctcagccatcccgcgcaataactg ggccgtaacgtgcgacagcgcgcagagcggcaacgagtgcaataaagccatcgac ggcaataaagacaccttctggcacacgttttatggcgcaaatggcgacccgaagc caccgcatacctataccattgacatgaaaaccacccagaatgtgaacgggctgtc cgtgctgccgcgccaggacggcaatcagaacggaaatatcggccgtcacgaggta tatttaagctccgacggcaccaactggggatccccggtcgcgtcgggcagctggt tcgccgacagcaccaccaagtattccaattttgaaacccgtcctgcacgctacgt gcgcttagtggccgtgacagaggcgaacggccagccatggacctcaatcgccgaa atcaatgtattccaagccagctcctataccgcgccgcagccaggacttgggcgtt ggggcccgaccatcgacctgcctatcgtacccgcagccgcggcgattgaaccaac gtcaggccgcgtactgatgtggagcagctaccgtaacgacgcggcggaaggcagc ccgggcggcatcactctgacgtcgagttgggatccatccacgggcatcgtctccg accgcaccgtgaccgtcacgaaacacgacatgttttgcccggggatcagcatgga cggcaacggccagatcgtcgtcacgggcggctgggacgccaagaagacgagcctc tatgacagtagcagcgacagttggatcccggggccggacatgcaggtggcacgcg ggtaccagtccagcgcgaccatgtcagacggccgtgtctttacaatcggcggctc atttagtggcggagtgtttgagaagaatggcgaagtctatagcccctcatccaaa acgtggacgtcacttccgaacgcgaaggtgaatcccatgttaaccgccgacaaac agggcctgtacatgagcgacaaccatgcgtggctgttcggctggaagaaggggag cgtctttcaggcgggcccgtcgaccgcaatgaattggtattacacgtcaggaagc ggggacgtgaaatcagccggcaagcgccagtcgaaccgcggcgtggcgccggacg caatgtgcggcaatgccgtgatgtatgacgcggtcaaaggcaagatcctgacatt tggcgggagtccggactacaccgacagtgacgcgacaaccaatgcccacattatt acccttggggagccggggacgagcccgaacacggtcttcgcgtccaatggcctct atttcgcgcgtacctttcatacgtcggtggtcctgccggacggatcaacctttat caccggcggacagcgccgtggcatccccttcgaagactcgacccccgtctttaca ccggagatttatgtgccggaacaggacacgttttataaacagaatccgaactcga ttgtacgcgcgtatcactccatcagccttcttctcccggacggacgtgtctttaa tggcggaggaggactgtgcggggactgcacgaccaatcattttgacgcgcagatc tttaccccgaattatctgtatgattcaaatgggaatctcgcgacccgtccgaaaa ttacccgtacatcaacccagtccgtcaaagtgggcggccgcattacgatcagtac cgacagcagcattaccaaagcgtcactgattcgttacggcaccgcaacccataca gtcaacacggaccagcgccgtattccgttaaccctgaccaataacggtggcaatt cgtatagcttccaggtaccgtcggactcgggcgtggcgctgccaggatactggat gctgtttgtgatgaatagcgcgggcgtcccgagcgtagcgagcacgatccgtgtg acccaggccgcagcttgataa 252 GOh2111 MGSSHHHHHHSSGLVPRGSHMGTASAPIGSAIPRNNWAVTCDSAQSGNECNKAID GNKDTFWHTFYGANGDPKPPHTYTIDMKTTQNVNGLSVLPRQDGNQNGNIGRHEV YLSSDGTNWGSPVASGSWFADSTTKYSNFETRPARYVRLVAVTEANGQPWTSIAE INVFQASSYTAPQPGLGRWGPTIDLPIVPAAAAIEPTSGRVLMWSSYRNDAAEGS PGGITLTSSWDPSTGIVSDRTVTVTKHDMFCPGISMDGNGQIVVTGGWDAKKTSL YDSSSDSWIPGPDMQVARGYQSSATMSDGRVFTIGGSFSGGVFEKNGEVYSPSSK TWTSLPNAKVNPMLTADKQGLYMSDNHAWLFGWKKGSVFQAGPSTAMNWYYTSGS GDVKSAGKRQSNRGVAPDAMCGNAVMYDAVKGKILTFGGSPDYTDSDATTNAHII TLGEPGTSPNTVFASNGLYFARTFHTSVVLPDGSTFITGGQRRGIPFEDSTPVFT PEIYVPEQDTFYKQNPNSIVRAYHSISLLLPDGRVFNGGGGLCGDCTTNHFDAQI FTPNYLYDSNGNLATRPKITRTSTQSVKVGGRITISTDSSITKASLIRYGTATHT VNTDQRRIPLTLTNNGGNSYSFQVPSDSGVALPGYWMLFVMNSAGVPSVASTIRV TQAAA 253 GOh2114 atgggcagcagccatcatcatcatcatcacagcagcggcctggtgccgcgcggca gccatatgggtaccgcctctgcccctatcggctcagccatcccgcgcaataactg ggccgtaacgtgcgacagcgcgcagagcggcaacgagtgcaataaagccatcgac ggcaataaagacaccttctggcacacgttttatggcgcaaatggcgacccgaagc caccgcatacctataccattgacatgaaaaccacccagaatgtgaacgggctgtc cgtgctgccgcgccaggacggcaatcagaacggatggatcggccgtcacgaggta tatttaagctccgacggcaccaactggggatccccggtcgcgtcgggcagctggt tcgccgacagcaccaccaagtattccaattttgaaacccgtcctgcacgctacgt gcgcttagtggccgtgacagaggcgaacggccagccatggacctcaatcgccgaa atcaatgtattccaagccagctcctatgaagcgccgcagccaggacttgggcgtt ggggcccgaccatcgacctgcctatcgtacccgcagccgcggcgattgaaccaac gtcaggccgcgtactgatgtggagcagctaccgtaacgacgcggcggaaggcagc ccgggcggcatcactctgacgtcgagttgggatccatccacgggcatcgtctccg accgcaccgtgaccgtcacgaaacacgacatgttttgcccggggatcagcatgga cggcaacggccagatcgtcgtcacgggcggctgggacgccaagaagacgagcctc tatgacagtagcagcgacagttggatcccggggccggacatgcaggtggcacgcg ggtaccagtccagcgcgaccatgtcagacggccgtgtctttacaatcggcggctc atttagtggcggagtgtttgagaagaatggcgaagtctatagcccctcatccaaa acgtggacgtcacttccgaacgcgaaggtgaatcccatgttaaccgccgacaaac agggcctgtacatgagcgacaaccatgcgtggctgttcggctggaagaaggggag cgtctttcaggcgggcccgtcgaccgcaatgaattggtattacacgtcaggaagc ggggacgtgaaatcagccggcaagcgccagtcgaaccgcggcgtggcgccggacg caatgtgcggcaatgccgtgatgtatgacgcggtcaaaggcaagatcctgacatt tggcgggagtccggactacaccgacagtgacgcgacaaccaatgcccacattatt acccttggggagccggggacgagcccgaacacggtcttcgcgtccaatggcctct atttcgcgcgtacctttcatacgtcggtggtcctgccggacggatcaacctttat caccggcggacagcgccgtggcatccccttcgaagactcgacccccgtctttaca ccggagatttatgtgccggaacaggacacgttttataaacagaatccgaactcga ttgtacgcgcgtatcactccatcagccttcttctcccggacggacgtgtctttaa tggcggaggaggactgtgcggggactgcacgaccaatcattttgacgcgcagatc tttaccccgaattatctgtatgattcaaatgggaatctcgcgacccgtccgaaaa ttacccgtacatcaacccagtccgtcaaagtgggggccgcattacgatcagtacc gacagcagcattaccaaagcgtcactgattcgttacggcaccgcaacccatacag tcaacacggaccagcgccgtattccgttaaccctgaccaataacggtggcaattc gtatagcttccaggtaccgtcggactcgggcgtggcgctgccaggatactggatg ctgtttgtgatgaatagcgcgggcgtcccgagcgtagcgagcacgatccgtgtga cccaggccgcagcttgataa 254 GOh2114 MGSSHHHHHHSSGLVPRGSHMGTASAPIGSAIPRNNWAVTCDSAQSGNECNKAID GNKDTFWHTFYGANGDPKPPHTYTIDMKTTQNVNGLSVLPRQDGNQNGWIGRHEV YLSSDGTNWGSPVASGSWFADSTTKYSNFETRPARYVRLVAVTEANGQPWTSIAE INVFQASSYEAPQPGLGRWGPTIDLPIVPAAAAIEPTSGRVLMWSSYRNDAAEGS PGGITLTSSWDPSTGIVSDRTVTVTKHDMFCPGISMDGNGQIVVTGGWDAKKTSL YDSSSDSWIPGPDMQVARGYQSSATMSDGRVFTIGGSFSGGVFEKNGEVYSPSSK TWTSLPNAKVNPMLTADKQGLYMSDNHAWLFGWKKGSVFQAGPSTAMNWYYTSGS GDVKSAGKRQSNRGVAPDAMCGNAVMYDAVKGKILTFGGSPDYTDSDATTNAHII TLGEPGTSPNTVFASNGLYFARTFHTSVVLPDGSTFITGGQRRGIPFEDSTPVFT PEIYVPEQDTFYKQNPNSIVRAYHSISLLLPDGRVFNGGGGLCGDCTTNHFDAQI FTPNYLYDSNGNLATRPKITRTSTQSVKVGGRITISTDSSITKASLIRYGTATHT VNTDQRRIPLTLTNNGGNSYSFQVPSDSGVALPGYWMLFVMNSAGVPSVASTIRV TQAAA 255 GOh2115 atgggcagcagccatcatcatcatcatcacagcagcggcctggtgccgcgcggca gccatatgggtaccgcctctgcccctatcggctcagccatcccgcgcaataactg ggccgtaacgtgcgacagcgcgcagagcggcaacgagtgcaataaagccatcgac ggcaataaagacaccttctggcacacgttttatggcgcaaatggcgacccgaagc caccgcatacctataccattgacatgaaaaccacccagaatgtgaacgggctgtc cgtgctgccgcgccaggacggcaatcagaacggatggatcggccgtcacgaggta tatttaagctccgacggcaccaactggggatccccggtcgcgtcgggcagctggt tcgccgacagcaccaccaagtattccaattttgaaacccgtcctgcacgctacgt gcgcttagtggccgtgacagaggcgaacggccagccatggacctcaatcgccgaa atcaatgtattccaagccagctcctatcatgcgccgcagccaggacttgggcgtt ggggcccgaccatcgacctgcctatcgtacccgcagccgcggcgattgaaccaac gtcaggccgcgtactgatgtggagcagctaccgtaacgacgcggcggaaggcagc ccgggcggcatcactctgacgtcgagttgggatccatccacgggcatcgtctccg accgcaccgtgaccgtcacgaaacacgacatgttttgcccggggatcagcatgga cggcaacggccagatcgtcgtcacgggcggctgggacgccaagaagacgagcctc tatgacagtagcagcgacagttggatcccggggccggacatgcaggtggcacgcg ggtaccagtccagcgcgaccatgtcagacggccgtgtctttacaatcggcggctc atttagtggcggagtgtttgagaagaatggcgaagtctatagcccctcatccaaa acgtggacgtcacttccgaacgcgaaggtgaatcccatgttaaccgccgacaaac agggcctgtacatgagcgacaaccatgcgtggctgttcggctggaagaaggggag cgtctttcaggcgggcccgtcgaccgcaatgaattggtattacacgtcaggaagc ggggacgtgaaatcagccggcaagcgccagtcgaaccgcggcgtggcgccggacg caatgtgcggcaatgccgtgatgtatgacgcggtcaaaggcaagatcctgacatt tggcgggagtccggactacaccgacagtgacgcgacaaccaatgcccacattatt acccttggggagccggggacgagcccgaacacggtcttcgcgtccaatggcctct atttcgcgcgtacctttcatacgtcggtggtcctgccggacggatcaacctttat caccggcggacagcgccgtggcatccccttcgaagactcgacccccgtctttaca ccggagatttatgtgccggaacaggacacgttttataaacagaatccgaactcga ttgtacgcgcgtatcactccatcagccttcttctcccggacggacgtgtctttaa tggcggaggaggactgtgcggggactgcacgaccaatcattttgacgcgcagatc tttaccccgaattatctgtatgattcaaatgggaatctcgcgacccgtccgaaaa ttacccgtacatcaacccagtccgtcaaagtgggcggccgcattacgatcagtac cgacagcagcattaccaaagcgtcactgattcgttacggcaccgcaacccataca gtcaacacggaccagcgccgtattccgttaaccctgaccaataacggtggcaatt cgtatagcttccaggtaccgtcggactcgggcgtggcgctgccaggatactggat gctgtttgtgatgaatagcgcgggcgtcccgagcgtagcgagcacgatccgtgtg acccaggccgcagcttgataa 256 GOh2115 MGSSHHHHHHSSGLVPRGSHMGTASAPIGSAIPRNNWAVTCDSAQSGNECNKAID GNKDTFWHTFYGANGDPKPPHTYTIDMKTTQNVNGLSVLPRQDGNQNGWIGRHEV YLSSDGTNWGSPVASGSWFADSTTKYSNFETRPARYVRLVAVTEANGQPWTSIAE INVFQASSYHAPQPGLGRWGPTIDLPIVPAAAAIEPTSGRVLMWSSYRNDAAEGS PGGITLTSSWDPSTGIVSDRTVTVTKHDMFCPGISMDGNGQIVVTGGWDAKKTSL YDSSSDSWIPGPDMQVARGYQSSATMSDGRVFTIGGSFSGGVFEKNGEVYSPSSK TWTSLPNAKVNPMLTADKQGLYMSDNHAWLFGWKKGSVFQAGPSTAMNWYYTSGS GDVKSAGKRQSNRGVAPDAMCGNAVMYDAVKGKILTFGGSPDYTDSDATTNAHII TLGEPGTSPNTVFASNGLYFARTFHTSVVLPDGSTFITGGQRRGIPFEDSTPVFT PEIYVPEQDTFYKQNPNSIVRAYHSISLLLPDGRVFNGGGGLCGDCTTNHFDAQI FTPNYLYDSNGNLATRPKITRTSTQSVKVGGRITISTDSSITKASLIRYGTATHT VNTDQRRIPLTLTNNGGNSYSFQVPSDSGVALPGYWMLFVMNSAGVPSVASTIRV TQAAA 257 GOh2116 atgggcagcagccatcatcatcatcatcacagcagcggcctggtgccgcgcggca gccatatgggtaccgcctctgcccctatcggctcagccatcccgcgcaataactg ggccgtaacgtgcgacagcgcgcagagcggcaacgagtgcaataaagccatcgac ggcaataaagacaccttctggcacacgttttatggcgcaaatggcgacccgaagc caccgcatacctataccattgacatgaaaaccacccagaatgtgaacgggctgtc cgtgctgccgcgccaggacggcaatcagaacggatggatcggccgtcacgaggta tatttaagctccgacggcaccaactggggatccccggtcgcgtcgggcagctggt tcgccgacagcaccaccaagtattccaattttgaaacccgtcctgcacgctacgt gcgcttagtggccgtgacagaggcgaacggccagccatggacctcaatcgccgaa atcaatgtattccaagccagctcctatattgcgccgcagccaggacttgggcgtt ggggcccgaccatcgacctgcctatcgtacccgcagccgcggcgattgaaccaac gtcaggccgcgtactgatgtggagcagctaccgtaacgacgcggcggaaggcagc ccgggcggcatcactctgacgtcgagttgggatccatccacgggcatcgtctccg accgcaccgtgaccgtcacgaaacacgacatgttttgcccggggatcagcatgga cggcaacggccagatcgtcgtcacgggcggctgggacgccaagaagacgagcctc tatgacagtagcagcgacagttggatcccggggccggacatgcaggtggcacgcg ggtaccagtccagcgcgaccatgtcagacggccgtgtctttacaatcggcggctc atttagtggcggagtgtttgagaagaatggcgaagtctatagcccctcatccaaa acgtggacgtcacttccgaacgcgaaggtgaatcccatgttaaccgccgacaaac agggcctgtacatgagcgacaaccatgcgtggctgttcggctggaagaaggggag cgtctttcaggcgggcccgtcgaccgcaatgaattggtattacacgtcaggaagc ggggacgtgaaatcagccggcaagcgccagtcgaaccgcggcgtggcgccggacg caatgtgcggcaatgccgtgatgtatgacgcggtcaaaggcaagatcctgacatt tggcgggagtccggactacaccgacagtgacgcgacaaccaatgcccacattatt acccttggggagccggggacgagcccgaacacggtcttcgcgtccaatggcctct atttcgcgcgtacctttcatacgtcggtggtcctgccggacggatcaacctttat caccggcggacagcgccgtggcatccccttcgaagactcgacccccgtctttaca ccggagatttatgtgccggaacaggacacgttttataaacagaatccgaactcga ttgtacgcgcgtatcactccatcagccttcttctcccggacggacgtgtctttaa tggcggaggaggactgtgcggggactgcacgaccaatcattttgacgcgcagatc tttaccccgaattatctgtatgattcaaatgggaatctcgcgacccgtccgaaaa ttacccgtacatcaacccagtccgtcaaagtgggcggccgcattacgatcagtac cgacagcagcattaccaaagcgtcactgattcgttacggcaccgcaacccataca gtcaacacggaccagcgccgtattccgttaaccctgaccaataacggtggcaatt cgtatagcttccaggtaccgtcggactcgggcgtggcgctgccaggatactggat gctgtttgtgatgaatagcgcgggcgtcccgagcgtagcgagcacgatccgtgtg acccaggccgcagcttgataa 258 GOh2116 MGSSHHHHHHSSGLVPRGSHMGTASAPIGSAIPRNNWAVTCDSAQSGNECNKAID GNKDTFWHTFYGANGDPKPPHTYTIDMKTTQNVNGLSVLPRQDGNQNGWIGRHEV YLSSDGTNWGSPVASGSWFADSTTKYSNFETRPARYVRLVAVTEANGQPWTSIAE INVFQASSYIAPQPGLGRWGPTIDLPIVPAAAAIEPTSGRVLMWSSYRNDAAEGS PGGITLTSSWDPSTGIVSDRTVTVTKHDMFCPGISMDGNGQIVVTGGWDAKKTSL YDSSSDSWIPGPDMQVARGYQSSATMSDGRVFTIGGSFSGGVFEKNGEVYSPSSK TWTSLPNAKVNPMLTADKQGLYMSDNHAWLFGWKKGSVFQAGPSTAMNWYYTSGS GDVKSAGKRQSNRGVAPDAMCGNAVMYDAVKGKILTFGGSPDYTDSDATTNAHII TLGEPGTSPNTVFASNGLYFARTFHTSVVLPDGSTFITGGQRRGIPFEDSTPVFT PEIYVPEQDTFYKQNPNSIVRAYHSISLLLPDGRVFNGGGGLCGDCTTNHFDAQI FTPNYLYDSNGNLATRPKITRTSTQSVKVGGRITISTDSSITKASLIRYGTATHT VNTDQRRIPLTLTNNGGNSYSFQVPSDSGVALPGYWMLFVMNSAGVPSVASTIRV TQAAA 259 GOh2117 atgggcagcagccatcatcatcatcatcacagcagcggcctggtgccgcgcggca gccatatgggtaccgcctctgcccctatcggctcagccatcccgcgcaataactg ggccgtaacgtgcgacagcgcgcagagcggcaacgagtgcaataaagccatcgac ggcaataaagacaccttctggcacacgttttatggcgcaaatggcgacccgaagc caccgcatacctataccattgacatgaaaaccacccagaatgtgaacgggctgtc cgtgctgccgcgccaggacggcaatcagaacggatggatcggccgtcacgaggta tatttaagctccgacggcaccaactggggatccccggtcgcgtcgggcagctggt tcgccgacagcaccaccaagtattccaattttgaaacccgtcctgcacgctacgt gcgcttagtggccgtgacagaggcgaacggccagccatggacctcaatcgccgaa atcaatgtattccaagccagctcctataaagcgccgcagccaggacttgggcgtt ggggcccgaccatcgacctgcctatcgtacccgcagccgcggcgattgaaccaac gtcaggccgcgtactgatgtggagcagctaccgtaacgacgcggcggaaggcagc ccgggcggcatcactctgacgtcgagttgggatccatccacgggcatcgtctccg accgcaccgtgaccgtcacgaaacacgacatgttttgcccggggatcagcatgga cggcaacggccagatcgtcgtcacgggcggctgggacgccaagaagacgagcctc tatgacagtagcagcgacagttggatcccggggccggacatgcaggtggcacgcg ggtaccagtccagcgcgaccatgtcagacggccgtgtctttacaatcggcggctc atttagtggcggagtgtttgagaagaatggcgaagtctatagcccctcatccaaa acgtggacgtcacttccgaacgcgaaggtgaatcccatgttaaccgccgacaaac agggcctgtacatgagcgacaaccatgcgtggctgttcggctggaagaaggggag cgtctttcaggcgggcccgtcgaccgcaatgaattggtattacacgtcaggaagc ggggacgtgaaatcagccggcaagcgccagtcgaaccgcggcgtggcgccggacg caatgtgcggcaatgccgtgatgtatgacgcggtcaaaggcaagatcctgacatt tgggggagtccggactacaccgacagtgacgcgacaaccaatgcccacattatta cccttggggagccggggacgagcccgaacacggtcttcgcgtccaatggcctcta tttcgcgcgtacctttcatacgtcggtggtcctgccggacggatcaacctttatc accggcggacagcgccgtggcatccccttcgaagactcgacccccgtctttacac cggagatttatgtgccggaacaggacacgttttataaacagaatccgaactcgat tgtacgcgcgtatcactccatcagccttcttctcccggacggacgtgtctttaat ggcggaggaggactgtgcggggactgcacgaccaatcattttgacgcgcagatct ttaccccgaattatctgtatgattcaaatgggaatctcgcgacccgtccgaaaat tacccgtacatcaacccagtccgtcaaagtgggggccgcattacgatcagtaccg acagcagcattaccaaagcgtcactgattcgttacggcaccgcaacccatacagt caacacggaccagcgccgtattccgttaaccctgaccaataacggtggcaattcg tatagcttccaggtaccgtcggactcgggcgtggcgctgccaggatactggatgc tgtttgtgatgaatagcgcgggcgtcccgagcgtagcgagcacgatccgtgtgac ccaggccgcagcttgataa 260 GOh2117 MGSSHHHHHHSSGLVPRGSHMGTASAPIGSAIPRNNWAVTCDSAQSGNECNKAID GNKDTFWHTFYGANGDPKPPHTYTIDMKTTQNVNGLSVLPRQDGNQNGWIGRHEV YLSSDGTNWGSPVASGSWFADSTTKYSNFETRPARYVRLVAVTEANGQPWTSIAE INVFQASSYKAPQPGLGRWGPTIDLPIVPAAAAIEPTSGRVLMWSSYRNDAAEGS PGGITLTSSWDPSTGIVSDRTVTVTKHDMFCPGISMDGNGQIVVTGGWDAKKTSL YDSSSDSWIPGPDMQVARGYQSSATMSDGRVFTIGGSFSGGVFEKNGEVYSPSSK TWTSLPNAKVNPMLTADKQGLYMSDNHAWLFGWKKGSVFQAGPSTAMNWYYTSGS GDVKSAGKRQSNRGVAPDAMCGNAVMYDAVKGKILTFGGSPDYTDSDATTNAHII TLGEPGTSPNTVFASNGLYFARTFHTSVVLPDGSTFITGGQRRGIPFEDSTPVFT PEIYVPEQDTFYKQNPNSIVRAYHSISLLLPDGRVFNGGGGLCGDCTTNHFDAQI FTPNYLYDSNGNLATRPKITRTSTQSVKVGGRITISTDSSITKASLIRYGTATHT VNTDQRRIPLTLTNNGGNSYSFQVPSDSGVALPGYWMLFVMNSAGVPSVASTIRV TQAAA 261 GOh2119 atgggcagcagccatcatcatcatcatcacagcagcggcctggtgccgcgcggca gccatatgggtaccgcctctgcccctatcggctcagccatcccgcgcaataactg ggccgtaacgtgcgacagcgcgcagagcggcaacgagtgcaataaagccatcgac ggcaataaagacaccttctggcacacgttttatggcgcaaatggcgacccgaagc caccgcatacctataccattgacatgaaaaccacccagaatgtgaacgggctgtc cgtgctgccgcgccaggacggcaatcagaacggatggatcggccgtcacgaggta tatttaagctccgacggcaccaactggggatccccggtcgcgtcgggcagctggt tcgccgacagcaccaccaagtattccaattttgaaacccgtcctgcacgctacgt gcgcttagtggccgtgacagaggcgaacggccagccatggacctcaatcgccgaa atcaatgtattccaagccagctcctataccgcgccgcagccaggacttgggcgtt ggggcccgaccatcgacctgcctatcgtacccgcagccgcggcgattgaaccaac gtcaggccgcgtactgatgtggagcagctaccgtaacgacgcggcggaaggcagc ccgggcggcatcactctgacgtcgagttgggatccatccacgggcatcgtctccg accgcaccgtgaccgtcacgaaacacgacatgttttgcccggggatcagcatgga cggcaacggccagatcgtcgtcacgggcggctgggacgccaagaagacgagcctc tatgacagtagcagcgacagttggatcccggggccggacatgcaggtggcacgcg ggtaccagtccagcgcgaccatgtcagacggccgtgtctttacaatcggcggctc atttagtggcggagtgtttgagaagaatggcgaagtctatagcccctcatccaaa acgtggacgtcacttccgaacgcgaaggtgaatcccatgttaaccgccgacaaac agggcctgtacatgagcgacaaccatgcgtggctgttcggctggaagaaggggag cgtctttcaggcgggcccgtcgaccgcaatgaattggtattacacgtcaggaagc ggggacgtgaaatcagccggcaagcgccagtcgaaccgcggcgtggatccggacg caatgtgcggcaatgccgtgatgtatgacgcggtcaaaggcaagatcctgacatt tggcgggagtccggactacaccgacagtgacgcgacaaccaatgcccacattatt acccttggggagccggggacgagcccgaacacggtcttcgcgtccaatggcctct atttcgcgcgtacctttcatacgtcggtggtcctgccggacggatcaacctttat caccggcggacagcgccgtggcatccccttcgaagactcgacccccgtctttaca ccggagatttatgtgccggaacaggacacgttttataaacagaatccgaactcga ttgtacgcgcgtatcactccatcagccttcttctcccggacggacgtgtctttaa tggcggaggaggactgtgcggggactgcacgaccaatcattttgacgcgcagatc tttaccccgaattatctgtatgattcaaatgggaatctcgcgacccgtccgaaaa ttacccgtacatcaacccagtccgtcaaagtgggcggccgcattacgatcagtac cgacagcagcattaccaaagcgtcactgattcgttacggcaccgcaacccataca gtcaacacggaccagcgccgtattccgttaaccctgaccaataacggtggcaatt cgtatagcttccaggtaccgtcggactcgggcgtggcgctgccaggatactggat gctgtttgtgatgaatagcgcgggcgtcccgagcgtagcgagcacgatccgtgtg acccaggccgcagcttgataa 262 GOh2119 MGSSHHHHHHSSGLVPRGSHMGTASAPIGSAIPRNNWAVTCDSAQSGNECNKAID GNKDTFWHTFYGANGDPKPPHTYTIDMKTTQNVNGLSVLPRQDGNQNGWIGRHEV YLSSDGTNWGSPVASGSWFADSTTKYSNFETRPARYVRLVAVTEANGQPWTSIAE INVFQASSYTAPQPGLGRWGPTIDLPIVPAAAAIEPTSGRVLMWSSYRNDAAEGS PGGITLTSSWDPSTGIVSDRTVTVTKHDMFCPGISMDGNGQIVVTGGWDAKKTSL YDSSSDSWIPGPDMQVARGYQSSATMSDGRVFTIGGSFSGGVFEKNGEVYSPSSK TWTSLPNAKVNPMLTADKQGLYMSDNHAWLFGWKKGSVFQAGPSTAMNWYYTSGS GDVKSAGKRQSNRGVDPDAMCGNAVMYDAVKGKILTFGGSPDYTDSDATTNAHII TLGEPGTSPNTVFASNGLYFARTFHTSVVLPDGSTFITGGQRRGIPFEDSTPVFT PEIYVPEQDTFYKQNPNSIVRAYHSISLLLPDGRVFNGGGGLCGDCTTNHFDAQI FTPNYLYDSNGNLATRPKITRTSTQSVKVGGRITISTDSSITKASLIRYGTATHT VNTDQRRIPLTLTNNGGNSYSFQVPSDSGVALPGYWMLFVMNSAGVPSVASTIRV TQAAA 263 GOh3001 atgggcagcagccatcatcatcatcatcacagcagcggcctggtgccgcgcggca gccatatgggtaccgcctctgcccctatcggctcagccatcccgcgcaataactg ggccgtaacgtgcgacagcgcgcagagcggcaacgagtgcaataaagccatcgac ggcaataaagacaccttctggcacacgttttatggcgcaaatggcgacccgaagc caccgcatacctataccattgacatgaaaaccacccagaatgtgaacgggctgtc cgtgctgccgcgccaggacggcaatcagaacggatggatcggccgtcacgaggta tatttaagctccgacggcaccaactggggatccccggtcgcgtcgggcagctggt tcgccgacagcaccaccaagtattccaattttgaaacccgtcctgcacgctacgt gcgcttagtggccgtgacagaggcgaacggccagccatggacctcaatcgccgaa atcaatgtattccaagccagctcctataccgcgccgcagccaggacttgggcgtt ggggcccgaccatcgacctgcctatcgtacccaccgccgcggcgattgaaccaac gtcaggccgcgtactgatgtggagcagctaccgtaacgacgcggcggaaggcagc ccgggcggcatcactctgacgtcgagttgggatccatccacgggcatcgtctccg accgcaccgtgaccgtcacgaaacacgacatgttttgcccggggatcagcatgga cggcaacggccagatcgtcgtcacgggcggctgggacgccaagaagacgagcctc tatgacagtagcagcgacagttggatcccggggccggacatgcaggtggcacgcg ggtaccagtccagcgcgaccatgtcagacggccgtgtctttacaatcggcggctc atttagtggcggagtgtttgagaagaatggcgaagtctatagcccctcatccaaa acgtggacgtcacttccgaacgcgaaggtgaatcccatgttaaccgccgacaaac agggcctgtggatgagcgacaaccatgcgtggctgttcggctggaagaaggggag cgtctttcaggcgggcccgtcgaccgcaatgaattggtattacacgtcaggaagc ggggacgtgaaatcagccggcaagcgccagtcgaaccgcggcgtggcgccggacg caatgtgcggcaatgccgtgatgtatgacgcggtcaaaggcaagatcctgacatt tggcgggagtccggactacaccgacagtgacgcgacaaccaatgcccacattatt acccttggggagccggggacgagcccgaacacggtcttcgcgtccaatggcctct atttcgcgcgtacctttcatacgtcggtggtcctgccggacggatcaacctttat caccggcggacagcgccgtggcatccccttcgaagactcgacccccgtctttaca ccggagatttatgtgccggaacaggacacgttttataaacagaatccgaactcga ttgtacgcgcgtatcactccatcagccttcttctcccggacggacgtgtctttaa tggcggaggaggactgtgcggggactgcacgaccaatcattttgacgcgcagatc tttaccccgaattatctgtatgattcaaatgggaatctcgcgacccgtccgaaaa ttacccgtacatcaacccagtccgtcaaagtgggcggccgcattacgatcagtac cgacagcagcattaccaaagcgtcactgattcgttacggcaccgcaacccataca gtcaacacggaccagcgccgtattccgttaaccctgaccaataacggtggcaatt cgtatagcttccaggtaccgtcggactcgggcgtggcgctgccaggatactggat gctgtttgtgatgaatagcgcgggcgtcccgagcgtagcgagcacgatccgtgtg acccaggccgcagcttgataa 264 GOh3001 MGSSHHHHHHSSGLVPRGSHMGTASAPIGSAIPRNNWAVTCDSAQSGNECNKAID GNKDTFWHTFYGANGDPKPPHTYTIDMKTTQNVNGLSVLPRQDGNQNGWIGRHEV YLSSDGTNWGSPVASGSWFADSTTKYSNFETRPARYVRLVAVTEANGQPWTSIAE INVFQASSYTAPQPGLGRWGPTIDLPIVPTAAAIEPTSGRVLMWSSYRNDAAEGS PGGITLTSSWDPSTGIVSDRTVTVTKHDMFCPGISMDGNGQIVVTGGWDAKKTSL YDSSSDSWIPGPDMQVARGYQSSATMSDGRVFTIGGSFSGGVFEKNGEVYSPSSK TWTSLPNAKVNPMLTADKQGLWMSDNHAWLFGWKKGSVFQAGPSTAMNWYYTSGS GDVKSAGKRQSNRGVAPDAMCGNAVMYDAVKGKILTFGGSPDYTDSDATTNAHII TLGEPGTSPNTVFASNGLYFARTFHTSVVLPDGSTFITGGQRRGIPFEDSTPVFT PEIYVPEQDTFYKQNPNSIVRAYHSISLLLPDGRVFNGGGGLCGDCTTNHFDAQI FTPNYLYDSNGNLATRPKITRTSTQSVKVGGRITISTDSSITKASLIRYGTATHT VNTDQRRIPLTLTNNGGNSYSFQVPSDSGVALPGYWMLFVMNSAGVPSVASTIRV TQAAA 265 GOh3002 atgggcagcagccatcatcatcatcatcacagcagcggcctggtgccgcgcggca gccatatgggtaccgcctctgcccctatcggctcagccatcccgcgcaataactg ggccgtaacgtgcgacagcgcgcagagcggcaacgagtgcaataaagccatcgac ggcaataaagacaccttctggcacacgttttatggcgcaaatggcgacccgaagc caccgcatacctataccattgacatgaaaaccacccagaatgtgaacgggctgtc cgtgctgccgcgccaggacggcaatcagaacggatggatcggccgtcacgaggta tatttaagctccgacggcaccaactggggatccccggtcgcgtcgggcagctggt tcgccgacagcaccaccaagtattccaattttgaaacccgtcctgcacgctacgt gcgcttagtggccgtgacagaggcgaacggccagccatggacctcaatcgccgaa atcaatgtattccaagccagctcctataccgcgccgcagccaggacttgggcgtt ggggcccgaccatcgacctgcctatcgtacccgcagccgcggcgattgaaccaac gtcaggccgcgtactgatgtggagcagctaccgtaacgacgcggcggaaggcagc ccgggcggcatcactctgacgtcgagttgggatccatccacgggcatcgtctccg accgcaccgtgaccgtcacgaaacacgacatgttttgcccggggatcagcatgga cggcaacggccagatcgtcgtcacgggcggctgggacgccaagaagacgagcctc tatgacagtagcagcgacagttggatcccggggccggacatgcaggtggcacgcg ggtaccagtccagcgcgaccatgtcagacggccgtgtctttacaatcggcggctc atttagtggcggagtgtttgagaagaatggcgaagtctatagcccctcatccaaa acgtggacgtcacttccgaacgcgaaggtgtggcccatgttaaccgccgacaaac agggcctgaccatgagcgacaaccatgcgtggctgttcggctggaagaaggggag cgtctttcaggcgggcccgtcgaccgcaatgaattggtattacacgtcaggaagc ggggacgtgaaatcagccggcaagcgccagtcgaaccgcggcgtggcgccggacg caatgtgcggcaatgccgtgatgtatgacgcggtcaaaggcaagatcctgacatt tggcgggagtccggactacaccgacagtgacgcgacaaccaatgcccacattatt acccttggggagccggggacgagcccgaacacggtcttcgcgtccaatggcctct atttcgcgcgtacctttcatacgtcggtggtcctgccggacggatcaacctttat caccggcggacagcgccgtggcatccccttcgaagactcgacccccgtctttaca ccggagatttatgtgccggaacaggacacgttttataaacagaatccgaactcga ttgtacgcgcgtatcactccatcagccttcttctcccggacggacgtgtctttaa tggcggaggaggactgtgcggggactgcacgaccaatcattttgacgcgcagatc tttaccccgaattatctgtatgattcaaatgggaatctcgcgacccgtccgaaaa ttacccgtacatcaacccagtccgtcaaagtgggcggccgcattacgatcagtac cgacagcagcattaccaaagcgtcactgattcgttacggcaccgcaacccataca gtcaacacggaccagcgccgtattccgttaaccctgaccaataacggtggcaatt cgtatagcttccaggtaccgtcggactcgggcgtggcgctgccaggatactggat gctgtttgtgatgaatagcgcgggcgtcccgagcgtagcgagcacgatccgtgtg acccaggccgcagcttgataa 266 GOh3002 MGSSHHHHHHSSGLVPRGSHMGTASAPIGSAIPRNNWAVTCDSAQSGNECNKAID GNKDTFWHTFYGANGDPKPPHTYTIDMKTTQNVNGLSVLPRQDGNQNGWIGRHEV YLSSDGTNWGSPVASGSWFADSTTKYSNFETRPARYVRLVAVTEANGQPWTSIAE INVFQASSYTAPQPGLGRWGPTIDLPIVPAAAAIEPTSGRVLMWSSYRNDAAEGS PGGITLTSSWDPSTGIVSDRTVTVTKHDMFCPGISMDGNGQIVVTGGWDAKKTSL YDSSSDSWIPGPDMQVARGYQSSATMSDGRVFTIGGSFSGGVFEKNGEVYSPSSK TWTSLPNAKVWPMLTADKQGLTMSDNHAWLFGWKKGSVFQAGPSTAMNWYYTSGS GDVKSAGKRQSNRGVAPDAMCGNAVMYDAVKGKILTFGGSPDYTDSDATTNAHII TLGEPGTSPNTVFASNGLYFARTFHTSVVLPDGSTFITGGQRRGIPFEDSTPVFT PEIYVPEQDTFYKQNPNSIVRAYHSISLLLPDGRVFNGGGGLCGDCTTNHFDAQI FTPNYLYDSNGNLATRPKITRTSTQSVKVGGRITISTDSSITKASLIRYGTATHT VNTDQRRIPLTLTNNGGNSYSFQVPSDSGVALPGYWMLFVMNSAGVPSVASTIRV TQAAA 267 GOh3003 atgggcagcagccatcatcatcatcatcacagcagcggcctggtgccgcgcggca gccatatgggtaccgcctctgcccctatcggctcagccatcccgcgcaataactg ggccgtaacgtgcgacagcgcgcagagcggcaacgagtgcaataaagccatcgac ggcaataaagacaccttctggcacacgttttatggcgcaaatggcgacccgaagc caccgcatacctataccattgacatgaaaaccacccagaatgtgaacgggctgtc cgtgctgccgcgccaggacggcaatcagaacggatggatcggccgtcacgaggta tatttaagctccgacggcaccaactggggatccccggtcgcgtcgggcagctggt tcgccgacagcaccaccaagtattccaattttgaaacccgtcctgcacgctacgt gcgcttagtggccgtgacagaggcgaacggccagccatggacctcaatcgccgaa atcaatgtattccaagccagctcctataccgcgccgcagccaggacttgggcgtt ggggcccgaccatcgacctgcctatcgtacccgcagccgcgattattgaaccaac gtcaggccgcgtactgatgtggagcagctaccgtaacgacgcggcggaaggcagc ccgggcggcatcactctgacgtcgagttgggatccatccacgggcatcgtctccg accgcaccgtgaccgtcacgaaacacgacatgttttgcccggggatcagcatgga cggcaccggccagatcgtcgtcacgggcggctgggacgccaagaagacgagcctc tatgacagtagcagcgacagttggatcccggggccggacatgcaggtggcacgcg ggtaccagtccagcgcgaccatgtcagacggccgtgtctttacaatcggcggctc atttagtggcggagtgtttgagaagaatggcgaagtctatagcccctcatccaaa acgtggacgtcacttccgaacgcgaaggtgaatcccatgttaaccgccgacaaac agggcctgtacatgagcgacaaccatgcgtggctgttcggctggaagaaggggag cgtctttcagggggcccgtcgaccgcaatgaattggtattacacgtcaggaagcg gggacgtgaaatcagccggcaagcgccagtcgaaccgcggcgtggcgccggacgc aatgtgcggcaatgccgtgatgtatgacgcggtcaaaggcaagatcctgacattt ggcgggagtccggactacaccgacagtgacgcgacaaccaatgcccacattatta cccttggggagccggggacgagcccgaacacggtcttcgcgtccaatggcctcta tttcgcgcgtacctttcatacgtcggtggtcctgccggacggatcaacctttatc accggcggacagcgccgtggcatccccttcgaagactcgacccccgtctttacac cggagatttatgtgccggaacaggacacgttttataaacagaatccgaactcgat tgtacgcgcgtatcactccatcagccttcttctcccggacggacgtgtctttaat ggcggaggaggactgtgcggggactgcacgaccaatcattttgacgcgcagatct ttaccccgaattatctgtatgattcaaatgggaatctcgcgacccgtccgaaaat tacccgtacatcaacccagtccgtcaaagtgggcggccgcattacgatcagtacc gacagcagcattaccaaagcgtcactgattcgttacggcaccgcaacccatacag tcaacacggaccagcgccgtattccgttaaccctgaccaataacggtggcaattc gtatagcttccaggtaccgtcggactcgggcgtggcgctgccaggatactggatg ctgtttgtgatgaatagcgcgggcgtcccgagcgtagcgagcacgatccgtgtga cccaggccgcagcttgataa 268 GOh3003 MGSSHHHHHHSSGLVPRGSHMGTASAPIGSAIPRNNWAVTCDSAQSGNECNKAID GNKDTFWHTFYGANGDPKPPHTYTIDMKTTQNVNGLSVLPRQDGNQNGWIGRHEV YLSSDGTNWGSPVASGSWFADSTTKYSNFETRPARYVRLVAVTEANGQPWTSIAE INVFQASSYTAPQPGLGRWGPTIDLPIVPAAAIIEPTSGRVLMWSSYRNDAAEGS PGGITLTSSWDPSTGIVSDRTVTVTKHDMFCPGISMDGTGQIVVTGGWDAKKTSL YDSSSDSWIPGPDMQVARGYQSSATMSDGRVFTIGGSFSGGVFEKNGEVYSPSSK TWTSLPNAKVNPMLTADKQGLYMSDNHAWLFGWKKGSVFQAGPSTAMNWYYTSGS GDVKSAGKRQSNRGVAPDAMCGNAVMYDAVKGKILTFGGSPDYTDSDATTNAHII TLGEPGTSPNTVFASNGLYFARTFHTSVVLPDGSTFITGGQRRGIPFEDSTPVFT PEIYVPEQDTFYKQNPNSIVRAYHSISLLLPDGRVFNGGGGLCGDCTTNHFDAQI FTPNYLYDSNGNLATRPKITRTSTQSVKVGGRITISTDSSITKASLIRYGTATHT VNTDQRRIPLTLTNNGGNSYSFQVPSDSGVALPGYWMLFVMNSAGVPSVASTIRV TQAAA 269 GOh3004 atgggcagcagccatcatcatcatcatcacagcagcggcctggtgccgcgcggca gccatatgggtaccgcctctgcccctatcggctcagccatcccgcgcaataactg ggccgtaacgtgcgacagcgcgcagagcggcaacgagtgcaataaagccatcgac ggcaataaagacaccttctggcacacgttttatggcgcaaatggcgacccgaagc caccgcatacctataccattgacatgaaaaccacccagaatgtgaacgggctgtc cgtgctgccgcgccaggacggcaatcagaacggatggatcggccgtcacgaggta tatttaagctccgacggcaccaactggggatccccggtcgcgtcgggcagctggt tcgccgacagcaccaccaagtattccaattttgaaacccgtcctgcacgctacgt gcgcttagtggccgtgacagaggcgaacggccagccatggacctcaatcgccgaa atcaatgtattccaagccagctcctataccgcgccgcagccaggacttgggcgtt ggggcccgaccatcgacctgcctatcgtacccagcgccgcggcgattgaaccaac gtcaggccgcgtactgatgtggagcagctaccgtaacgacgcggcggaaggcagc ccgggcggcatcactctgacgtcgagttgggatccatccacgggcatcgtctccg accgcaccgtgaccgtcacgaaacacgacatgttttgcccggggatcagcatgga cggcaacggccagatcgtcgtcacgggcggctgggacgccaagaagacgagcctc tatgacagtagcagcgacagttggatcccggggccggacatgcaggtggcacgcg ggtaccagtccagcgcgaccatgtcagacggccgtgtctttacaatcggcggctc atttagtggcggagtgtttgagaagaatggcgaagtctatagcccctcatccaaa acgtggacgtcacttccgaacgcgaaggtgtggcccatgttaaccgccgacaaac agggcctgtacatgagcgacaaccatgcgtggctgttcggctggaagaaggggag cgtctttcaggcgggcccgtcgaccgcaatgaattggtattacacgtcaggaagc ggggacgtgaaatcagccggcaagcgccagtcgaaccgcggcgtggcgccggacg caatgtgcggcaatgccgtgatgtatgacgcggtcaaaggcaagatcctgacatt tggcgggagtccggactacaccgacagtgacgcgacaaccaatgcccacattatt acccttggggagccggggacgagcccgaacacggtcttcgcgtccaatggcctct atttcgcgcgtacctttcatacgtcggtggtcctgccggacggatcaacctttat caccggcggacagcgccgtggcatccccttcgaagactcgacccccgtctttaca ccggagatttatgtgccggaacaggacacgttttataaacagaatccgaactcga ttgtacgcgcgtatcactccatcagccttcttctcccggacggacgtgtctttaa tggcggaggaggactgtgcggggactgcacgaccaatcattttgacgcgcagatc tttaccccgaattatctgtatgattcaaatgggaatctcgcgacccgtccgaaaa ttacccgtacatcaacccagtccgtcaaagtgggcggccgcattacgatcagtac cgacagcagcattaccaaagcgtcactgattcgttacggcaccgcaacccataca gtcaacacggaccagcgccgtattccgttaaccctgaccaataacggtggcaatt cgtatagcttccaggtaccgtcggactcgggcgtggcgctgccaggatactggat gctgtttgtgatgaatagcgcgggcgtcccgagcgtagcgagcacgatccgtgtg acccaggccgcagcttgataa 270 GOh3004 MGSSHHHHHHSSGLVPRGSHMGTASAPIGSAIPRNNWAVTCDSAQSGNECNKAID GNKDTFWHTFYGANGDPKPPHTYTIDMKTTQNVNGLSVLPRQDGNQNGWIGRHEV YLSSDGTNWGSPVASGSWFADSTTKYSNFETRPARYVRLVAVTEANGQPWTSIAE INVFQASSYTAPQPGLGRWGPTIDLPIVPSAAAIEPTSGRVLMWSSYRNDAAEGS PGGITLTSSWDPSTGIVSDRTVTVTKHDMFCPGISMDGNGQIVVTGGWDAKKTSL YDSSSDSWIPGPDMQVARGYQSSATMSDGRVFTIGGSFSGGVFEKNGEVYSPSSK TWTSLPNAKVWPMLTADKQGLYMSDNHAWLFGWKKGSVFQAGPSTAMNWYYTSGS GDVKSAGKRQSNRGVAPDAMCGNAVMYDAVKGKILTFGGSPDYTDSDATTNAHII TLGEPGTSPNTVFASNGLYFARTFHTSVVLPDGSTFITGGQRRGIPFEDSTPVFT PEIYVPEQDTFYKQNPNSIVRAYHSISLLLPDGRVFNGGGGLCGDCTTNHFDAQI FTPNYLYDSNGNLATRPKITRTSTQSVKVGGRITISTDSSITKASLIRYGTATHT VNTDQRRIPLTLTNNGGNSYSFQVPSDSGVALPGYWMLFVMNSAGVPSVASTIRV TQAAA 271 GOh3005 atgggcagcagccatcatcatcatcatcacagcagcggcctggtgccgcgcggca gccatatgggtaccgcctctgcccctatcggctcagccatcccgcgcaataactg ggccgtaacgtgcgacagcgcgcagagcggcaacgagtgcaataaagccatcgac ggcaataaagacaccttctggcacacgttttatggcgcaaatggcgacccgaagc caccgcatacctataccattgacatgaaaaccacccagaatgtgaacgggctgtc cgtgctgccgcgccaggacggcaatcagaacggatggatcggccgtcacgaggta tatttaagctccgacggcaccaactggggatccccggtcgcgtcgggcagctggt tcgccgacagcaccaccaagtattccaattttgaaacccgtcctgcacgctacgt gcgcttagtggccgtgaaagaggcgaacggccagccatggacctcaatcgccgaa atcaatgtattccaagccagctcctataccgcgccgcagccaggacttgggcgtt ggggcccgaccatcgacctgcctatcgtacccagcgccgcggcgattgaaccaac gtcaggccgcgtactgatgtggagcagctaccgtaacgacgcggcggaaggcagc ccgggcggcatcactctgacgtcgagttgggatccatccacgggcatcgtctccg accgcaccgtgaccgtcacgaaacacgacatgttttgcccggggatcagcatgga cggcaacggccagatcgtcgtcacgggcggctgggacgccaagaagacgagcctc tatgacagtagcagcgacagttggatcccggggccggacatgcaggtggcacgcg ggtaccagtccagcgcgaccatgtcagacggccgtgtctttacaatcggcggctc atttagtggcggagtgtttgagaagaatggcgaagtctatagcccctcatccaaa acgtggacgtcacttccgaacgcgaaggtgaatcccatgttaaccgccgacaaac agggcctgtacatgagcgacaaccatgcgtggctgttcggctggaagaaggggag cgtctttcaggcgggcccgtcgaccgcaatgaattggtattacacgtcaggaagc ggggacgtgaaatcagccggcaagcgccagtcgaaccgcggcgtggcgccggacg caatgtgcggcaatgccgtgatgtatgacgcggtcaaaggcaagatcctgacatt tggcgggagtccggactacaccgacagtgacgcgacaaccaatgcccacattatt acccttggggagccggggacgagcccgaacacggtcttcgcgtccaatggcctct atttcgcgcgtacctttcatacgtcggtggtcctgccggacggatcaacctttat caccggcggacagcgccgtggcatccccttcgaagactcgacccccgtctttaca ccggagatttatgtgccggaacaggacacgttttataaacagaatccgaactcga ttgtacgcgcgtatcactccatcagccttcttctcccggacggacgtgtctttaa tggcggaggaggactgtgcggggactgcacgaccaatcattttgacgcgcagatc tttaccccgaattatctgtatgattcaaatgggaatctcgcgacccgtccgaaaa ttacccgtacatcaacccagtccgtcaaagtgggcggccgcattacgatcagtac cgacagcagcattaccaaagcgtcactgattcgttacggcaccgcaacccataca gtcaacacggaccagcgccgtattccgttaaccctgaccaataacggtggcaatt cgtatagcttccaggtaccgtcggactcgggcgtggcgctgccaggatactggat gctgtttgtgatgaatagcgcgggcgtcccgagcgtagcgagcacgatccgtgtg acccaggccgcagcttgataa 272 GOh3005 MGSSHHHHHHSSGLVPRGSHMGTASAPIGSAIPRNNWAVTCDSAQSGNECNKAID GNKDTFWHTFYGANGDPKPPHTYTIDMKTTQNVNGLSVLPRQDGNQNGWIGRHEV YLSSDGTNWGSPVASGSWFADSTTKYSNFETRPARYVRLVAVKEANGQPWTSIAE INVFQASSYTAPQPGLGRWGPTIDLPIVPSAAAIEPTSGRVLMWSSYRNDAAEGS PGGITLTSSWDPSTGIVSDRTVTVTKHDMFCPGISMDGNGQIVVTGGWDAKKTSL YDSSSDSWIPGPDMQVARGYQSSATMSDGRVFTIGGSFSGGVFEKNGEVYSPSSK TWTSLPNAKVNPMLTADKQGLYMSDNHAWLFGWKKGSVFQAGPSTAMNWYYTSGS GDVKSAGKRQSNRGVAPDAMCGNAVMYDAVKGKILTFGGSPDYTDSDATTNAHII TLGEPGTSPNTVFASNGLYFARTFHTSVVLPDGSTFITGGQRRGIPFEDSTPVFT PEIYVPEQDTFYKQNPNSIVRAYHSISLLLPDGRVFNGGGGLCGDCTTNHFDAQI FTPNYLYDSNGNLATRPKITRTSTQSVKVGGRITISTDSSITKASLIRYGTATHT VNTDQRRIPLTLTNNGGNSYSFQVPSDSGVALPGYWMLFVMNSAGVPSVASTIRV TQAAA 273 GOh3006 atgggcagcagccatcatcatcatcatcacagcagcggcctggtgccgcgcggca gccatatgggtaccgcctctgcccctcgtggctcagccatcccgcgcaataactg ggccgtaacgtgcgacagcgcgcagagcggcaacgagtgcaataaagccatcgac ggcaataaagacaccttctggcacacgttttatggcgcaaatggcgacccgaagc caccgcatacctataccattgacatgaaaaccacccagaatgtgaacgggctgtc cgtgctgccgcgccaggacggcaatcagaacggatggatcggccgtcacgaggta tatttaagctccgacggcaccaactggggatccccggtcgcgtcgggcagctggt tcgccgacagcaccaccaagtattccaattttgaaacccgtcctgcacgctacgt gcgcttagtggccgtgacagaggcgaacggccagccatggacctcaatcgccgaa atcaatgtattccaagccagctcctataccgcgccgcagccaggacttgggcgtt ggggcccgaccatcgacctgcctatcgtacccgcagccgcggcgattgaaccaac gtcaggccgcgtactgatgtggagcagctaccgtaacgacgcggcggaaggcagc ccgggcggcatcactctgacgtcgagttgggatccatccacgggcatcgtctccg accgcaccgtgaccgtcacgaaacacgacatgttttgcccggggatcagcatgga cggcaacggccagatcgtcgtcacgggcggctgggacgccaagaagacgagcctc tatgacagtagcagcgacagttggatcccggggccggacatgcaggtggcacgcg ggtaccagtccagcgcgaccatgtcagacggccgtgtctttacaatcggcggctc atttagtggcggagtgtttgagaagaatggcgaagtctatagcccctcatccaaa acgtggacgtcacttccgaacgcgaaggtgaatcccatgttaaccgccgacaaac agggcctgtacatgagcgacaaccatgcgtggctgttcggctggaagaaggggag cgtctttcagggggcccgtcgaccgcaatgaattggtattacacgtcaggaagcg gggacgtgatctcagccggcaagcgccagtcgaaccgcggcgtggcgccggacgc aatgtgcggcaatgccgtgatgtatgacgcggtcaaaggcaagatcctgacattt ggcgggagtccggactacaccgacagtgacgcgacaaccaatgcccacattatta cccttggggagccggggacgagcccgaacacggtcttcgcgtccaatggcctcta tttcgcgcgtacctttcatacgtcggtggtcctgccggacggatcaacctttatc accggcggacagcgccgtggcatccccttcgaagactcgacccccgtctttacac cggagatttatgtgccggaacaggacacgttttataaacagaatccgaactcgat tgtacgcgcgtatcactccatcagccttcttctcccggacggacgtgtctttaat ggcggaggaggactgtgcggggactgcacgaccaatcattttgacgcgcagatct ttaccccgaattatctgtatgattcaaatgggaatctcgcgacccgtccgaaaat tacccgtacatcaacccagtccgtcaaagtgggcggccgcattacgatcagtacc gacagcagcattaccaaagcgtcactgattcgttacggcaccgcaacccatacag tcaacacggaccagcgccgtattccgttaaccctgaccaataacggtggcaattc gtatagcttccaggtaccgtcggactcgggcgtggcgctgccaggatactggatg ctgtttgtgatgaatagcgcgggcgtcccgagcgtagcgagcacgatccgtgtga cccaggccgcagcttgataa 274 GOh3006 MGSSHHHHHHSSGLVPRGSHMGTASAPRGSAIPRNNWAVTCDSAQSGNECNKAID GNKDTFWHTFYGANGDPKPPHTYTIDMKTTQNVNGLSVLPRQDGNQNGWIGRHEV YLSSDGTNWGSPVASGSWFADSTTKYSNFETRPARYVRLVAVTEANGQPWTSIAE INVFQASSYTAPQPGLGRWGPTIDLPIVPAAAAIEPTSGRVLMWSSYRNDAAEGS PGGITLTSSWDPSTGIVSDRTVTVTKHDMFCPGISMDGNGQIVVTGGWDAKKTSL YDSSSDSWIPGPDMQVARGYQSSATMSDGRVFTIGGSFSGGVFEKNGEVYSPSSK TWTSLPNAKVNPMLTADKQGLYMSDNHAWLFGWKKGSVFQAGPSTAMNWYYTSGS GDVISAGKRQSNRGVAPDAMCGNAVMYDAVKGKILTFGGSPDYTDSDATTNAHII TLGEPGTSPNTVFASNGLYFARTFHTSVVLPDGSTFITGGQRRGIPFEDSTPVFT PEIYVPEQDTFYKQNPNSIVRAYHSISLLLPDGRVFNGGGGLCGDCTTNHFDAQI FTPNYLYDSNGNLATRPKITRTSTQSVKVGGRITISTDSSITKASLIRYGTATHT VNTDQRRIPLTLTNNGGNSYSFQVPSDSGVALPGYWMLFVMNSAGVPSVASTIRV TQAAA 275 GOh3007 atgggcagcagccatcatcatcatcatcacagcagcggcctggtgccgcgcggca gccatatgggtaccgcctctgcccctatcggctcagccatcccgcgcaataactg ggccgtaacgtgcgacagcgcgcagagcggcaacgagtgcaataaagccatcgac ggcaataaagacaccttctggcacacgttttatggcgcaaatggcgacccgaagc caccgcatacctataccattgacatgaaaaccacccagaatgtgaacgggctgtc cgtgctgccgcgccaggacggcaatcagaacggatggatcggccgtcacgaggta tatttaagctccgacggcaccaactggggatccccggtcgcgtcgggcagctggt tcgccgacagcaccaccaagtattccaattttgaaacccgtcctgcacgctacgt gcgcttagtggccgtgcgtgaggcgaacggccagccatggacctcaatcgccgaa atcaatgtattccaagccagctcctataccgcgccgcagccaggacttgggcgtt ggggcccgaccatcgacctgcctatcgtacccaccgccgcggcgattgaaccaac gtcaggccgcgtactgatgtggagcagctaccgtaacgacgcggcggaaggcagc ccgggcggcatcactctgacgtcgagttgggatccatccacgggcatcgtctccg accgcaccgtgaccgtcacgaaacacgacatgttttgcccggggatcagcatgga cggcaacggccagatcgtcgtcacgggcggctgggacgccaagaagacgagcctc tatgacagtagcagcgacagttggatcccggggccggacatgcaggtggcacgcg ggtaccagtccagcgcgaccatgtcagacggccgtgtctttacaatcggcggctc atttagtggcggagtgtttgagaagaatggcgaagtctatagcccctcatccaaa acgtggacgtcacttccgaacgcgaaggtgaatcccatgttaaccgccgacaaac agggcctgtacatgagcgacaaccatgcgtggctgttcggctggaagaaggggag cgtctttcaggcgggcccgtcgaccgcaatgaattggtattacacgtcaggaagc ggggacgtgaaatcagccggcaagcgccagtcgaaccgcggcgtggcgccggacg caatgtgcggcaatgccgtgatgtatgacgcggtcaaaggcaagatcctgacatt tggcgggagtccggactacaccgacagtgacgcgacaaccaatgcccacattatt acccttggggagccggggacgagcccgaacacggtcttcgcgtccaatggcctct atttcgcgcgtacctttcatacgtcggtggtcctgccggacggatcaacctttat caccggcggacagcgccgtggcatccccttcgaagactcgacccccgtctttaca ccggagatttatgtgccggaacaggacacgttttataaacagaatccgaactcga ttgtacgcgcgtatcactccatcagccttcttctcccggacggacgtgtctttaa tggcggaggaggactgtgcggggactgcacgaccaatcattttgacgcgcagatc tttaccccgaattatctgtatgattcaaatgggaatctcgcgacccgtccgaaaa ttacccgtacatcaacccagtccgtcaaagtgggcggccgcattacgatcagtac cgacagcagcattaccaaagcgtcactgattcgttacggcaccgcaacccataca gtcaacacggaccagcgccgtattccgttaaccctgaccaataacggtggcaatt cgtatagcttccaggtaccgtcggactcgggcgtggcgctgccaggatactggat gctgtttgtgatgaatagcgcgggcgtcccgagcgtagcgagcacgatccgtgtg acccaggccgcagcttgataa 276 GOh3007 MGSSHHHHHHSSGLVPRGSHMGTASAPIGSAIPRNNWAVTCDSAQSGNECNKAID GNKDTFWHTFYGANGDPKPPHTYTIDMKTTQNVNGLSVLPRQDGNQNGWIGRHEV YLSSDGTNWGSPVASGSWFADSTTKYSNFETRPARYVRLVAVREANGQPWTSIAE INVFQASSYTAPQPGLGRWGPTIDLPIVPTAAAIEPTSGRVLMWSSYRNDAAEGS PGGITLTSSWDPSTGIVSDRTVTVTKHDMFCPGISMDGNGQIVVTGGWDAKKTSL YDSSSDSWIPGPDMQVARGYQSSATMSDGRVFTIGGSFSGGVFEKNGEVYSPSSK TWTSLPNAKVNPMLTADKQGLYMSDNHAWLFGWKKGSVFQAGPSTAMNWYYTSGS GDVKSAGKRQSNRGVAPDAMCGNAVMYDAVKGKILTFGGSPDYTDSDATTNAHII TLGEPGTSPNTVFASNGLYFARTFHTSVVLPDGSTFITGGQRRGIPFEDSTPVFT PEIYVPEQDTFYKQNPNSIVRAYHSISLLLPDGRVFNGGGGLCGDCTTNHFDAQI FTPNYLYDSNGNLATRPKITRTSTQSVKVGGRITISTDSSITKASLIRYGTATHT VNTDQRRIPLTLTNNGGNSYSFQVPSDSGVALPGYWMLFVMNSAGVPSVASTIRV TQAAA 277 GOh3008 atgggcagcagccatcatcatcatcatcacagcagcggcctggtgccgcgcggca gccatatgggtaccgcctctgcccctcgtggctcagccatcccgcgcaataactg ggccgtaacgtgcgacagcgcgcagagcggcaacgagtgcaataaagccatcgac ggcaataaagacaccttctggcacacgttttatggcgcaaatggcgacccgaagc caccgcatacctataccattgacatgaaaaccacccagaatgtgaacgggctgtc cgtgctgccgcgccaggacggcaatcagaacggatggatcggccgtcacgaggta tatttaagctccgacggcaccaactggggatccccggtcgcgtcgggcagctggt tcgccgacagcaccaccaagtattccaattttgaaacccgtcctgcacgctacgt gcgcttagtggccgtgcgtgaggcgaacggccagccatggacctcaatcgccgaa atcaatgtattccaagccagctcctataccgcgccgcagccaggacttgggcgtt ggggcccgaccatcgacctgcctatcgtacccgcagccgcgattattgaaccaac gtcaggccgcgtactgatgtggagcagctaccgtaacgacgcggcggaaggcagc ccgggcggcatcactctgacgtcgagttgggatccatccacgggcatcgtctccg accgcaccgtgaccgtcacgaaacacgacatgttttgcccggggatcagcatgga cggcaacggccagatcgtcgtcacgggcggctgggacgccaagaagacgagcctc tatgacagtagcagcgacagttggatcccggggccggacatgcaggtggcacgcg ggtaccagtccagcgcgaccatgtcagacggccgtgtctttacaatcggcggctc atttagtggcggagtgtttgagaagaatggcgaagtctatagcccctcatccaaa acgtggacgtcacttccgaacgcgaaggtgtggcccatgttaaccgccgacaaac agggcctgtacatgagcgacaaccatgcgtggctgttcggctggaagaaggggag cgtctttcaggcgggcccgtcgaccgcaatgaattggtattacacgtcaggaagc ggggacgtgaaatcagccggcaagcgccagtcgaaccgcggcgtggcgccggacg caatgtgcggcaatgccgtgatgtatgacgcggtcaaaggcaagatcctgacatt tggcgggagtccggactacaccgacagtgacgcgacaaccaatgcccacattatt acccttggggagccggggacgagcccgaacacggtcttcgcgtccaatggcctct atttcgcgcgtacctttcatacgtcggtggtcctgccggacggatcaacctttat caccggcggacagcgccgtggcatccccttcgaagactcgacccccgtctttaca ccggagatttatgtgccggaacaggacacgttttataaacagaatccgaactcga ttgtacgcgcgtatcactccatcagccttcttctcccggacggacgtgtctttaa tggcggaggaggactgtgcggggactgcacgaccaatcattttgacgcgcagatc tttaccccgaattatctgtatgattcaaatgggaatctcgcgacccgtccgaaaa ttacccgtacatcaacccagtccgtcaaagtgggcggccgcattacgatcagtac cgacagcagcattaccaaagcgtcactgattcgttacggcaccgcaacccataca gtcaacacggaccagcgccgtattccgttaaccctgaccaataacggtggcaatt cgtatagcttccaggtaccgtcggactcgggcgtggcgctgccaggatactggat gctgtttgtgatgaatagcgcgggcgtcccgagcgtagcgagcacgatccgtgtg acccaggccgcagcttgataa 278 GOh3008 MGSSHHHHHHSSGLVPRGSHMGTASAPRGSAIPRNNWAVTCDSAQSGNECNKAID GNKDTFWHTFYGANGDPKPPHTYTIDMKTTQNVNGLSVLPRQDGNQNGWIGRHEV YLSSDGTNWGSPVASGSWFADSTTKYSNFETRPARYVRLVAVREANGQPWTSIAE INVFQASSYTAPQPGLGRWGPTIDLPIVPAAAIIEPTSGRVLMWSSYRNDAAEGS PGGITLTSSWDPSTGIVSDRTVTVTKHDMFCPGISMDGNGQIVVTGGWDAKKTSL YDSSSDSWIPGPDMQVARGYQSSATMSDGRVFTIGGSFSGGVFEKNGEVYSPSSK TWTSLPNAKVWPMLTADKQGLYMSDNHAWLFGWKKGSVFQAGPSTAMNWYYTSGS GDVKSAGKRQSNRGVAPDAMCGNAVMYDAVKGKILTFGGSPDYTDSDATTNAHII TLGEPGTSPNTVFASNGLYFARTFHTSVVLPDGSTFITGGQRRGIPFEDSTPVFT PEIYVPEQDTFYKQNPNSIVRAYHSISLLLPDGRVFNGGGGLCGDCTTNHFDAQI FTPNYLYDSNGNLATRPKITRTSTQSVKVGGRITISTDSSITKASLIRYGTATHT VNTDQRRIPLTLTNNGGNSYSFQVPSDSGVALPGYWMLFVMNSAGVPSVASTIRV TQAAA 279 GOh3009 atgggcagcagccatcatcatcatcatcacagcagcggcctggtgccgcgcggca gccatatgggtaccgcctctgcccctatcggctcagccatcccgcgcaataactg ggccgtaacgtgcgacagcgcgcagagcggcaacgagtgcaataaagccatcgac ggcaataaagacaccttctggcacacgttttatggcgcaaatggcgacccgaagc caccgcatacctataccattgacatgaaaaccacccagaatgtgaacgggctgtc cgtgctgccgcgccaggacggcaatcagaacggatggatcggccgtcacgaggta tatttaagctccgacggcaccaactggggatccccggtcgcgtcgggcagctggt tcgccgacagcaccaccaagtattccaattttgaaacccgtcctgcacgctacgt gcgcttagtggccgtgacagaggcgaacggccagccatggacctcaatcgccgaa atcaatgtattccaagccagctcctataccgcgccgcagccaggacttgggcgtt ggggcccgaccatcgacctgcctatcgtacccaccgccgcggcgattgaaccaac gtcaggccgcgtactgatgtggagcagctaccgtaacgacgcggcggaaggcagc ccgggcggcatcactctgacgtcgagttgggatccatccacgggcatcgtctccg accgcaccgtgaccgtcacgaaacacgacatgttttgcccggggatcagcatgga cggcaccggccagatcgtcgtcacgggcggctgggacgccaagaagacgagcctc tatgacagtagcagcgacagttggatcccggggccggacatgcaggtggcacgcg ggtaccagtccagcgcgaccatgtcagacggccgtgtctttacaatcggcggctc atttagtggcggagtgtttgagaagaatggcgaagtctatagcccctcatccaaa acgtggacgtcacttccgaacgcgaaggtgtggcccatgttaaccgccgacaaac agggcctgtacatgagcgacaaccatgcgtggctgttcggctggaagaaggggag cgtctttcaggcgggcccgtcgaccgcaatgaattggtattacacgtcaggaagc ggggacgtgaaatcagccggcaagcgccagtcgaaccgcggcgtggcgccggacg caatgtgcggcaatgccgtgatgtatgacgcggtcaaaggcaagatcctgacatt tggcgggagtccggactacaccgacagtgacgcgacaaccaatgcccacattatt acccttggggagccggggacgagcccgaacacggtcttcgcgtccaatggcctct atttcgcgcgtacctttcatacgtcggtggtcctgccggacggatcaacctttat caccggcggacagcgccgtggcatccccttcgaagactcgacccccgtctttaca ccggagatttatgtgccggaacaggacacgttttataaacagaatccgaactcga ttgtacgcgcgtatcactccatcagccttcttctcccggacggacgtgtctttaa tggcggaggaggactgtgcggggactgcacgaccaatcattttgacgcgcagatc tttaccccgaattatctgtatgattcaaatgggaatctcgcgacccgtccgaaaa ttacccgtacatcaacccagtccgtcaaagtgggcggccgcattacgatcagtac cgacagcagcattaccaaagcgtcactgattcgttacggcaccgcaacccataca gtcaacacggaccagcgccgtattccgttaaccctgaccaataacggtggcaatt cgtatagcttccaggtaccgtcggactcgggcgtggcgctgccaggatactggat gctgtttgtgatgaatagcgcgggcgtcccgagcgtagcgagcacgatccgtgtg acccaggccgcagcttgataa 280 GOh3009 MGSSHHHHHHSSGLVPRGSHMGTASAPIGSAIPRNNWAVTCDSAQSGNECNKAID GNKDTFWHTFYGANGDPKPPHTYTIDMKTTQNVNGLSVLPRQDGNQNGWIGRHEV YLSSDGTNWGSPVASGSWFADSTTKYSNFETRPARYVRLVAVTEANGQPWTSIAE INVFQASSYTAPQPGLGRWGPTIDLPIVPTAAAIEPTSGRVLMWSSYRNDAAEGS PGGITLTSSWDPSTGIVSDRTVTVTKHDMFCPGISMDGTGQIVVTGGWDAKKTSL YDSSSDSWIPGPDMQVARGYQSSATMSDGRVFTIGGSFSGGVFEKNGEVYSPSSK TWTSLPNAKVWPMLTADKQGLYMSDNHAWLFGWKKGSVFQAGPSTAMNWYYTSGS GDVKSAGKRQSNRGVAPDAMCGNAVMYDAVKGKILTFGGSPDYTDSDATTNAHII TLGEPGTSPNTVFASNGLYFARTFHTSVVLPDGSTFITGGQRRGIPFEDSTPVFT PEIYVPEQDTFYKQNPNSIVRAYHSISLLLPDGRVFNGGGGLCGDCTTNHFDAQI FTPNYLYDSNGNLATRPKITRTSTQSVKVGGRITISTDSSITKASLIRYGTATHT VNTDQRRIPLTLTNNGGNSYSFQVPSDSGVALPGYWMLFVMNSAGVPSVASTIRV TQAAA 281 GOh3013 atgggcagcagccatcatcatcatcatcacagcagcggcctggtgccgcgcggca gccatatgggtaccgcctctgcccctcgtggctcagccatcccgcgcaataactg ggccgtaacgtgcgacagcgcgcagagcggcaacgagtgcaataaagccatcgac ggcaataaagacaccttctggcacacgttttatggcgcaaatggcgacccgaagc caccgcatacctataccattgacatgaaaaccacccagaatgtgaacgggctgtc cgtgctgccgcgccaggacggcaatcagaacggatggatcggccgtcacgaggta tatttaagctccgacggcaccaactggggatccccggtcgcgtcgggcagctggt tcgccgacagcaccaccaagtattccaattttgaaacccgtcctgcacgctacgt gcgcttagtggccgtgacagaggcgaacggccagccatggacctcaatcgccgaa atcaatgtattccaagccagctcctataccgcgccgcagccaggacttgggcgtt ggggcccgaccatcgacctgcctatcgtacccaccgccgcggcgattgaaccaac gtcaggccgcgtactgatgtggagcagctaccgtaacgacgcggcggaaggcagc ccgggcggcatcactctgacgtcgagttgggatccatccacgggcatcgtctccg accgcaccgtgaccgtcacgaaacacgacatgttttgcccggggatcagcatgga cggcaccggccagatcgtcgtcacgggcggctgggacgccaagaagacgagcctc tatgacagtagcagcgacagttggatcccggggccggacatgcaggtggcacgcg ggtaccagtccagcgcgaccatgtcagacggccgtgtctttacaatcggcggctc atttagtggcggagtgtttgagaagaatggcgaagtctatagcccctcatccaaa acgtggacgtcacttccgaacgcgaaggtgaatcccatgttaaccgccgacaaac agggcctgtacatgagcgacaaccatgcgtggctgttcggctggaagaaggggag cgtctttcaggcgggcccgtcgaccgcaatgaattggtattacacgtcaggaagc ggggacgtgatctcagccggcaagcgccagtcgaaccgcggcgtggcgccggacg caatgtgcggcaatgccgtgatgtatgacgcggtcaaaggcaagatcctgacatt tggcgggagtccggactacaccgacagtgacgcgacaaccaatgcccacattatt acccttggggagccggggacgagcccgaacacggtcttcgcgtccaatggcctct atttcgcgcgtacctttcatacgtcggtggtcctgccggacggatcaacctttat caccggcggacagcgccgtggcatccccttcgaagactcgacccccgtctttaca ccggagatttatgtgccggaacaggacacgttttataaacagaatccgaactcga ttgtacgcgcgtatcactccatcagccttcttctcccggacggacgtgtctttaa tggcggaggaggactgtgcggggactgcacgaccaatcattttgacgcgcagatc tttaccccgaattatctgtatgattcaaatgggaatctcgcgacccgtccgaaaa ttacccgtacatcaacccagtccgtcaaagtgggcggccgcattacgatcagtac cgacagcagcattaccaaagcgtcactgattcgttacggcaccgcaacccataca gtcaacacggaccagcgccgtattccgttaaccctgaccaataacggtggcaatt cgtatagcttccaggtaccgtcggactcgggcgtggcgctgccaggatactggat gctgtttgtgatgaatagcgcgggcgtcccgagcgtagcgagcacgatccgtgtg acccaggccgcagcttgataa 282 GOh3013 MGSSHHHHHHSSGLVPRGSHMGTASAPRGSAIPRNNWAVTCDSAQSGNECNKAID GNKDTFWHTFYGANGDPKPPHTYTIDMKTTQNVNGLSVLPRQDGNQNGWIGRHEV YLSSDGTNWGSPVASGSWFADSTTKYSNFETRPARYVRLVAVTEANGQPWTSIAE INVFQASSYTAPQPGLGRWGPTIDLPIVPTAAAIEPTSGRVLMWSSYRNDAAEGS PGGITLTSSWDPSTGIVSDRTVTVTKHDMFCPGISMDGTGQIVVTGGWDAKKTSL YDSSSDSWIPGPDMQVARGYQSSATMSDGRVFTIGGSFSGGVFEKNGEVYSPSSK TWTSLPNAKVNPMLTADKQGLYMSDNHAWLFGWKKGSVFQAGPSTAMNWYYTSGS GDVISAGKRQSNRGVAPDAMCGNAVMYDAVKGKILTFGGSPDYTDSDATTNAHII TLGEPGTSPNTVFASNGLYFARTFHTSVVLPDGSTFITGGQRRGIPFEDSTPVFT PEIYVPEQDTFYKQNPNSIVRAYHSISLLLPDGRVFNGGGGLCGDCTTNHFDAQI FTPNYLYDSNGNLATRPKITRTSTQSVKVGGRITISTDSSITKASLIRYGTATHT VNTDQRRIPLTLTNNGGNSYSFQVPSDSGVALPGYWMLFVMNSAGVPSVASTIRV TQAAA 283 GOh3015 atgggcagcagccatcatcatcatcatcacagcagcggcctggtgccgcgcggca gccatatgggtaccgcctctgcccctcgtggctcagccatcccgcgcaataactg ggccgtaacgtgcgacagcgcgcagagcggcaacgagtgcaataaagccatcgac ggcaataaagacaccttctggcacacgttttatggcgcaaatggcgacccgaagc caccgcatacctataccattgacatgaaaaccacccagaatgtgaacgggctgtc cgtgctgccgcgccaggacggcaatcagaacggatggatcggccgtcacgaggta tatttaagctccgacggcaccaactggggatccccggtcgcgtcgggcagctggt tcgccgacagcaccaccaagtattccaattttgaaacccgtcctgcacgctacgt gcgcttagtggccgtgacagaggcgaacggccagccatggacctcaatcgccgaa atcaatgtattccaagccagctcctataccgcgccgcagccaggacttgggcgtt ggggcccgaccatcgacctgcctatcgtacccgcagccgcggcgattgaaccaac gtcaggccgcgtactgatgtggagcagctaccgtaacgacgcggcggaaggcagc ccgggcggcatcactctgacgtcgagttgggatccatccacgggcatcgtctccg accgcaccgtgaccgtcacgaaacacgacatgttttgcccggggatcagcatgga cggcaccggccagatcgtcgtcacgggcggctgggacgccaagaagacgagcctc tatgacagtagcagcgacagttggatcccggggccggacatgcaggtggcacgcg ggtaccagtccagcgcgaccatgtcagacggccgtgtctttacaatcggcggctc atttagtggcggagtgtttgagaagaatggcgaagtctatagcccctcatccaaa acgtggacgtcacttccgaacgcgaaggtgtggcccatgttaaccgccgacaaac agggcctgtacatgagcgacaaccatgcgtggctgttcggctggaagaaggggag cgtctttcaggcgggcccgtcgaccgcaatgaattggtattacacgtcaggaagc ggggacgtgaaatcagccggcaagcgccagtcgaaccgcggcgtggcgccggacg caatgtgcggcaatgccgtgatgtatgacgcggtcaaaggcaagatcctgacatt tggcgggagtccggactacaccgacagtgacgcgacaaccaatgcccacattatt acccttggggagccggggacgagcccgaacacggtcttcgcgtccaatggcctct atttcgcgcgtacctttcatacgtcggtggtcctgccggacggatcaacctttat caccggcggacagcgccgtggcatccccttcgaagactcgacccccgtctttaca ccggagatttatgtgccggaacaggacacgttttataaacagaatccgaactcga ttgtacgcgcgtatcactccatcagccttcttctcccggacggacgtgtctttaa tggcggaggaggactgtgcggggactgcacgaccaatcattttgacgcgcagatc tttaccccgaattatctgtatgattcaaatgggaatctcgcgacccgtccgaaaa ttacccgtacatcaacccagtccgtcaaagtgggggccgcattacgatcagtacc gacagcagcattaccaaagcgtcactgattcgttacggcaccgcaacccatacag tcaacacggaccagcgccgtattccgttaaccctgaccaataacggtggcaattc gtatagcttccaggtaccgtcggactcgggcgtggcgctgccaggatactggatg ctgtttgtgatgaatagcgcgggcgtcccgagcgtagcgagcacgatccgtgtga cccaggccgcagcttgataa 284 GOh3015 MGSSHHHHHHSSGLVPRGSHMGTASAPRGSAIPRNNWAVTCDSAQSGNECNKAID GNKDTFWHTFYGANGDPKPPHTYTIDMKTTQNVNGLSVLPRQDGNQNGWIGRHEV YLSSDGTNWGSPVASGSWFADSTTKYSNFETRPARYVRLVAVTEANGQPWTSIAE INVFQASSYTAPQPGLGRWGPTIDLPIVPAAAAIEPTSGRVLMWSSYRNDAAEGS PGGITLTSSWDPSTGIVSDRTVTVTKHDMFCPGISMDGTGQIVVTGGWDAKKTSL YDSSSDSWIPGPDMQVARGYQSSATMSDGRVFTIGGSFSGGVFEKNGEVYSPSSK TWTSLPNAKVWPMLTADKQGLYMSDNHAWLFGWKKGSVFQAGPSTAMNWYYTSGS GDVKSAGKRQSNRGVAPDAMCGNAVMYDAVKGKILTFGGSPDYTDSDATTNAHII TLGEPGTSPNTVFASNGLYFARTFHTSVVLPDGSTFITGGQRRGIPFEDSTPVFT PEIYVPEQDTFYKQNPNSIVRAYHSISLLLPDGRVFNGGGGLCGDCTTNHFDAQI FTPNYLYDSNGNLATRPKITRTSTQSVKVGGRITISTDSSITKASLIRYGTATHT VNTDQRRIPLTLTNNGGNSYSFQVPSDSGVALPGYWMLFVMNSAGVPSVASTIRV TQAAA 285 GOh3018 atgggcagcagccatcatcatcatcatcacagcagcggcctggtgccgcgcggca gccatatgggtaccgcctctgcccctcgtggctcagccatcccgcgcaataactg ggccgtaacgtgcgacagcgcgcagagcggcaacgagtgcaataaagccatcgac ggcaataaagacaccttctggcacacgttttatggcgcaaatggcgacccgaagc caccgcatacctataccattgacatgaaaaccacccagaatgtgaacgggctgtc cgtgctgccgcgccaggacggcaatcagaacggatggatcggccgtcacgaggta tatttaagctccgacggcaccaactggggatccccggtcgcgtcgggcagctggt tcgccgacagcaccaccaagtattccaattttgaaacccgtcctgcacgctacgt gcgcttagtggccgtgacagaggcgaacggccagccatggacctcaatcgccgaa atcaatgtattccaagccagctcctataccgcgccgcagccaggacttgggcgtt ggggcccgaccatcgacctgcctatcgtacccagcgccgcggcgattgaaccaac gtcaggccgcgtactgatgtggagcagctaccgtaacgacgcggcggaaggcagc ccgggcggcatcactctgacgtcgagttgggatccatccacgggcatcgtctccg accgcaccgtgaccgtcacgaaacacgacatgttttgcccggggatcagcatgga cggcaacggccagatcgtcgtcacgggcggctgggacgccaagaagacgagcctc tatgacagtagcagcgacagttggatcccggggccggacatgcaggtggcacgcg ggtaccagtccagcgcgaccatgtcagacggccgtgtctttacaatcggcggctc atttagtggcggagtgtttgagaagaatggcgaagtctatagcccctcatccaaa acgtggacgtcacttccgaacgcgaaggtgaatcccatgttaaccgccgacaaac agggcctgtacatgagcgacaaccatgcgtggctgttcggctggaagaaggggag cgtctttcaggcgggcccgtcgaccgcaatgaattggtattacacgtcaggaagc ggggacgtgatctcagccggcaagcgccagtcgaaccgcggcgtggcgccggacg caatgtgcggcaatgccgtgatgtatgacgcggtcaaaggcaagatcctgacatt tggcgggagtccggactacaccgacagtgacgcgacaaccaatgcccacattatt acccttggggagccggggacgagcccgaacacggtcttcgcgtccaatggcctct atttcgcgcgtacctttcatacgtcggtggtcctgccggacggatcaacctttat caccggcggacagcgccgtggcatccccttcgaagactcgacccccgtctttaca ccggagatttatgtgccggaacaggacacgttttataaacagaatccgaactcga ttgtacgcgcgtatcactccatcagccttcttctcccggacggacgtgtctttaa tggcggaggaggactgtgcggggactgcacgaccaatcattttgacgcgcagatc tttaccccgaattatctgtatgattcaaatgggaatctcgcgacccgtccgaaaa ttacccgtacatcaacccagtccgtcaaagtgggcggccgcattacgatcagtac cgacagcagcattaccaaagcgtcactgattcgttacggcaccgcaacccataca gtcaacacggaccagcgccgtattccgttaaccctgaccaataacggtggcaatt cgtatagcttccaggtaccgtcggactcgggcgtggcgctgccaggatactggat gctgtttgtgatgaatagcgcgggcgtcccgagcgtagcgagcacgatccgtgtg acccaggccgcagcttgataa 286 GOh3018 MGSSHHHHHHSSGLVPRGSHMGTASAPRGSAIPRNNWAVTCDSAQSGNECNKAID GNKDTFWHTFYGANGDPKPPHTYTIDMKTTQNVNGLSVLPRQDGNQNGWIGRHEV YLSSDGTNWGSPVASGSWFADSTTKYSNFETRPARYVRLVAVTEANGQPWTSIAE INVFQASSYTAPQPGLGRWGPTIDLPIVPSAAAIEPTSGRVLMWSSYRNDAAEGS PGGITLTSSWDPSTGIVSDRTVTVTKHDMFCPGISMDGNGQIVVTGGWDAKKTSL YDSSSDSWIPGPDMQVARGYQSSATMSDGRVFTIGGSFSGGVFEKNGEVYSPSSK TWTSLPNAKVNPMLTADKQGLYMSDNHAWLFGWKKGSVFQAGPSTAMNWYYTSGS GDVISAGKRQSNRGVAPDAMCGNAVMYDAVKGKILTFGGSPDYTDSDATTNAHII TLGEPGTSPNTVFASNGLYFARTFHTSVVLPDGSTFITGGQRRGIPFEDSTPVFT PEIYVPEQDTFYKQNPNSIVRAYHSISLLLPDGRVFNGGGGLCGDCTTNHFDAQI FTPNYLYDSNGNLATRPKITRTSTQSVKVGGRITISTDSSITKASLIRYGTATHT VNTDQRRIPLTLTNNGGNSYSFQVPSDSGVALPGYWMLFVMNSAGVPSVASTIRV TQAAA 287 GOh3019 atgggcagcagccatcatcatcatcatcacagcagcggcctggtgccgcgcggca gccatatgggtaccgcctctgcccctatcggctcagccatcccgcgcaataactg ggccgtaacgtgcgacagcgcgcagagcggcaacgagtgcaataaagccatcgac ggcaataaagacaccttctggcacacgttttatggcgcaaatggcgacccgaagc caccgcatacctataccattgacatgaaaaccacccagaatgtgaacgggctgtc cgtgctgccgcgccaggacggcaatcagaacggatggatcggccgtcacgaggta tatttaagctccgacggcaccaactggggatccccggtcgcgtcgggcagctggt tcgccgacagcaccaccaagtattccaattttgaaacccgtcctgcacgctacgt gcgcttagtggccgtgacagaggcgaacggccagccatggacctcaatcgccgaa atcaatgtattccaagccagctcctataccgcgccgcagccaggacttgggcgtt ggggcccgaccatcgacctgcctatcgtacccaccgccgcggcgattgaaccaac gtcaggccgcgtactgatgtggagcagctaccgtaacgacgcggcggaaggcagc ccgggcggcatcactctgacgtcgagttgggatccatccacgggcatcgtctccg accgcaccgtgaccgtcacgaaacacgacatgttttgcccggggatcagcatgga cggcaacggccagatcgtcgtcacgggcggctgggacgccaagaagacgagcctc tatgacagtagcagcgacagttggatcccggggccggacatgcaggtggcacgcg ggtaccagtccagcgcgaccatgtcagacggccgtgtctttacaatcggcggctc atttagtggcggagtgtttgagaagaatggcgaagtctatagcccctcatccaaa acgtggacgtcacttccgaacgcgaaggtgtggcccatgttaaccgccgacaaac agggcctgtacatgagcgacaaccatgcgtggctgttcggctggaagaaggggag cgtctttcaggcgggcccgtcgaccgcaatgaattggtattacacgtcaggaagc ggggacgtgaaatcagccggcaagcgccagtcgaaccgcggcgtggcgccggacg caatgtgcggcaatgccgtgatgtatgacgcggtcaaaggcaagatcctgacatt tggcgggagtccggactacaccgacagtgacgcgacaaccaatgcccacattatt acccttggggagccggggacgagcccgaacacggtcttcgcgtccaatggcctct atttcgcgcgtacctttcatacgtcggtggtcctgccggacggatcaacctttat caccggcggacagcgccgtggcatccccttcgaagactcgacccccgtctttaca ccggagatttatgtgccggaacaggacacgttttataaacagaatccgaactcga ttgtacgcgcgtatcactccatcagccttcttctcccggacggacgtgtctttaa tggcggaggaggactgtgcggggactgcacgaccaatcattttgacgcgcagatc tttaccccgaattatctgtatgattcaaatgggaatctcgcgacccgtccgaaaa ttacccgtacatcaacccagtccgtcaaagtgggcggccgcattacgatcagtac cgacagcagcattaccaaagcgtcactgattcgttacggcaccgcaacccataca gtcaacacggaccagcgccgtattccgttaaccctgaccaataacggtggcaatt cgtatagcttccaggtaccgtcggactcgggcgtggcgctgccaggatactggat gctgtttgtgatgaatagcgcgggcgtcccgagcgtagcgagcacgatccgtgtg acccaggccgcagcttgataa 288 GOh3019 MGSSHHHHHHSSGLVPRGSHMGTASAPIGSAIPRNNWAVTCDSAQSGNECNKAID GNKDTFWHTFYGANGDPKPPHTYTIDMKTTQNVNGLSVLPRQDGNQNGWIGRHEV YLSSDGTNWGSPVASGSWFADSTTKYSNFETRPARYVRLVAVTEANGQPWTSIAE INVFQASSYTAPQPGLGRWGPTIDLPIVPTAAAIEPTSGRVLMWSSYRNDAAEGS PGGITLTSSWDPSTGIVSDRTVTVTKHDMFCPGISMDGNGQIVVTGGWDAKKTSL YDSSSDSWIPGPDMQVARGYQSSATMSDGRVFTIGGSFSGGVFEKNGEVYSPSSK TWTSLPNAKVWPMLTADKQGLYMSDNHAWLFGWKKGSVFQAGPSTAMNWYYTSGS GDVKSAGKRQSNRGVAPDAMCGNAVMYDAVKGKILTFGGSPDYTDSDATTNAHII TLGEPGTSPNTVFASNGLYFARTFHTSVVLPDGSTFITGGQRRGIPFEDSTPVFT PEIYVPEQDTFYKQNPNSIVRAYHSISLLLPDGRVFNGGGGLCGDCTTNHFDAQI FTPNYLYDSNGNLATRPKITRTSTQSVKVGGRITISTDSSITKASLIRYGTATHT VNTDQRRIPLTLTNNGGNSYSFQVPSDSGVALPGYWMLFVMNSAGVPSVASTIRV TQAAA 289 GOh3023 atgggcagcagccatcatcatcatcatcacagcagcggcctggtgccgcgcggca gccatatgggtaccgcctctgcccctcgtggctcagccatcccgcgcaataactg ggccgtaacgtgcgacagcgcgcagagcggcaacgagtgcaataaagccatcgac ggcaataaagacaccttctggcacacgttttatggcgcaaatggcgacccgaagc caccgcatacctataccattgacatgaaaaccacccagaatgtgaacgggctgtc cgtgctgccgcgccaggacggcaatcagaacggatggatcggccgtcacgaggta tatttaagctccgacggcaccaactggggatccccggtcgcgtcgggcagctggt tcgccgacagcaccaccaagtattccaattttgaaacccgtcctgcacgctacgt gcgcttagtggccgtgacagaggcgaacggccagccatggacctcaatcgccgaa atcaatgtattccaagccagctcctataccgcgccgcagccaggacttgggcgtt ggggcccgaccatcgacctgcctatcgtacccaccgccgcggcgattgaaccaac gtcaggccgcgtactgatgtggagcagctaccgtaacgacgcggcggaaggcagc ccgggcggcatcactctgacgtcgagttgggatccatccacgggcatcgtctccg accgcaccgtgaccgtcacgaaacacgacatgttttgcccggggatcagcatgga cggcaacggccagatcgtcgtcacgggcggctgggacgccaagaagacgagcctc tatgacagtagcagcgacagttggatcccggggccggacatgcaggtggcacgcg ggtaccagtccagcgcgaccatgtcagacggccgtgtctttacaatcggcggctc atttagtggcggagtgtttgagaagaatggcgaagtctatagcccctcatccaaa acgtggacgtcacttccgaacgcgaaggtgtggcccatgttaaccgccgacaaac agggcctgtacatgagcgacaaccatgcgtggctgttcggctggaagaaggggag cgtctttcagggggcccgtcgaccgcaatgaattggtattacacgtcaggaagcg gggacgtgatctcagccggcaagcgccagtcgaaccgcggcgtggcgccggacgc aatgtgcggcaatgccgtgatgtatgacgcggtcaaaggcaagatcctgacattt ggcgggagtccggactacaccgacagtgacgcgacaaccaatgcccacattatta cccttggggagccggggacgagcccgaacacggtcttcgcgtccaatggcctcta tttcgcgcgtacctttcatacgtcggtggtcctgccggacggatcaacctttatc accggcggacagcgccgtggcatccccttcgaagactcgacccccgtctttacac cggagatttatgtgccggaacaggacacgttttataaacagaatccgaactcgat tgtacgcgcgtatcactccatcagccttcttctcccggacggacgtgtctttaat ggcggaggaggactgtgcggggactgcacgaccaatcattttgacgcgcagatct ttaccccgaattatctgtatgattcaaatgggaatctcgcgacccgtccgaaaat tacccgtacatcaacccagtccgtcaaagtgggcggccgcattacgatcagtacc gacagcagcattaccaaagcgtcactgattcgttacggcaccgcaacccatacag tcaacacggaccagcgccgtattccgttaaccctgaccaataacggtggcaattc gtatagcttccaggtaccgtcggactcgggcgtggcgctgccaggatactggatg ctgtttgtgatgaatagcgcgggcgtcccgagcgtagcgagcacgatccgtgtga cccaggccgcagcttgataa 290 GOh3023 MGSSHHHHHHSSGLVPRGSHMGTASAPRGSAIPRNNWAVTCDSAQSGNECNKAID GNKDTFWHTFYGANGDPKPPHTYTIDMKTTQNVNGLSVLPRQDGNQNGWIGRHEV YLSSDGTNWGSPVASGSWFADSTTKYSNFETRPARYVRLVAVTEANGQPWTSIAE INVFQASSYTAPQPGLGRWGPTIDLPIVPTAAAIEPTSGRVLMWSSYRNDAAEGS PGGITLTSSWDPSTGIVSDRTVTVTKHDMFCPGISMDGNGQIVVTGGWDAKKTSL YDSSSDSWIPGPDMQVARGYQSSATMSDGRVFTIGGSFSGGVFEKNGEVYSPSSK TWTSLPNAKVWPMLTADKQGLYMSDNHAWLFGWKKGSVFQAGPSTAMNWYYTSGS GDVISAGKRQSNRGVAPDAMCGNAVMYDAVKGKILTFGGSPDYTDSDATTNAHII TLGEPGTSPNTVFASNGLYFARTFHTSVVLPDGSTFITGGQRRGIPFEDSTPVFT PEIYVPEQDTFYKQNPNSIVRAYHSISLLLPDGRVFNGGGGLCGDCTTNHFDAQI FTPNYLYDSNGNLATRPKITRTSTQSVKVGGRITISTDSSITKASLIRYGTATHT VNTDQRRIPLTLTNNGGNSYSFQVPSDSGVALPGYWMLFVMNSAGVPSVASTIRV TQAAA 291 GOh3026 atgggcagcagccatcatcatcatcatcacagcagcggcctggtgccgcgcggca gccatatgggtaccgcctctgcccctcgtggctcagccatcccgcgcaataactg ggccgtaacgtgcgacagcgcgcagagcggcaacgagtgcaataaagccatcgac ggcaataaagacaccttctggcacacgttttatggcgcaaatggcgacccgaagc caccgcatacctataccattgacatgaaaaccacccagaatgtgaacgggctgtc cgtgctgccgcgccaggacggcaatcagaacggatggatcggccgtcacgaggta tatttaagctccgacggcaccaactggggatccccggtcgcgtcgggcagctggt tcgccgacagcaccaccaagtattccaattttgaaacccgtcctgcacgctacgt gcgcttagtggccgtgacagaggcgaacggccagccatggacctcaatcgccgaa atcaatgtattccaagccagctcctataccgcgccgcagccaggacttgggcgtt ggggcccgaccatcgacctgcctatcgtacccaccgccgcggcgattgaaccaac gtcaggccgcgtactgatgtggagcagctaccgtaacgacgcggcggaaggcagc ccgggcggcatcactctgacgtcgagttgggatccatccacgggcatcgtctccg accgcaccgtgaccgtcacgaaacacgacatgttttgcccggggatcagcatgga cggcaccggccagatcgtcgtcacgggcggctgggacgccaagaagacgagcctc tatgacagtagcagcgacagttggatcccggggccggacatgcaggtggcacgcg ggtaccagtccagcgcgaccatgtcagacggccgtgtctttacaatcggcggctc atttagtggcggagtgtttgagaagaatggcgaagtctatagcccctcatccaaa acgtggacgtcacttccgaacgcgaaggtgaatcccatgttaaccgccgacaaac agggcctgtacatgagcgacaaccatgcgtggctgttcggctggaagaaggggag cgtctttcaggcgggcccgtcgaccgcaatgaattggtattacacgtcaggaagc ggggacgtgaaatcagccggcaagcgccagtcgaaccgcggcgtggcgccggacg caatgtgcggcaatgccgtgatgtatgacgcggtcaaaggcaagatcctgacatt tggcgggagtccggactacaccgacagtgacgcgacaaccaatgcccacattatt acccttggggagccgggggcgagcccgaacacggtcttcgcgtccaatggcctct atttcgcgcgtacctttcatacgtcggtggtcctgccggacggatcaacctttat caccggcggacagcgccgtggcatccccttcgaagactcgacccccgtctttaca ccggagatttatgtgccggaacaggacacgttttataaacagaatccgaactcga ttgtacgcgcgtatcactccatcagccttcttctcccggacggacgtgtctttaa tggcggaggaggactgtgcggggactgcacgaccaatcattttgacgcgcagatc tttaccccgaattatctgtatgattcaaatgggaatctcgcgacccgtccgaaaa ttacccgtacatcaacccagtccgtcaaagtgggcggccgcattacgatcagtac cgacagcagcattaccaaagcgtcactgattcgttacggcaccgcaacccataca gtcaacacggaccagcgccgtattccgttaaccctgaccaataacggtggcaatt cgtatagcttccaggtaccgtcggactcgggcgtggcgctgccaggatactggat gctgtttgtgatgaatagcgcgggcgtcccgagcgtagcgagcacgatccgtgtg acccaggccgcagcttgataa 292 GOh3026 MGSSHHHHHHSSGLVPRGSHMGTASAPRGSAIPRNNWAVTCDSAQSGNECNKAID GNKDTFWHTFYGANGDPKPPHTYTIDMKTTQNVNGLSVLPRQDGNQNGWIGRHEV YLSSDGTNWGSPVASGSWFADSTTKYSNFETRPARYVRLVAVTEANGQPWTSIAE INVFQASSYTAPQPGLGRWGPTIDLPIVPTAAAIEPTSGRVLMWSSYRNDAAEGS PGGITLTSSWDPSTGIVSDRTVTVTKHDMFCPGISMDGTGQIVVTGGWDAKKTSL YDSSSDSWIPGPDMQVARGYQSSATMSDGRVFTIGGSFSGGVFEKNGEVYSPSSK TWTSLPNAKVNPMLTADKQGLYMSDNHAWLFGWKKGSVFQAGPSTAMNWYYTSGS GDVKSAGKRQSNRGVAPDAMCGNAVMYDAVKGKILTFGGSPDYTDSDATTNAHII TLGEPGASPNTVFASNGLYFARTFHTSVVLPDGSTFITGGQRRGIPFEDSTPVFT PEIYVPEQDTFYKQNPNSIVRAYHSISLLLPDGRVFNGGGGLCGDCTTNHFDAQI FTPNYLYDSNGNLATRPKITRTSTQSVKVGGRITISTDSSITKASLIRYGTATHT VNTDQRRIPLTLTNNGGNSYSFQVPSDSGVALPGYWMLFVMNSAGVPSVASTIRV TQAAA 293 GOh3032 atgggcagcagccatcatcatcatcatcacagcagcggcctggtgccgcgcggca gccatatgggtaccgcctctgcccctcgtggctcagccatcccgcgcaataactg ggccgtaacgtgcgacagcgcgcagagcggcaacgagtgcaataaagccatcgac ggcaataaagacaccttctggcacacgttttatggcgcaaatggcgacccgaagc caccgcatacctataccattgacatgaaaaccacccagaatgtgaacgggctgtc cgtgctgccgcgccaggacggcaatcagaacggatggatcggccgtcacgaggta tatttaagctccgacggcaccaactggggatccccggtcgcgtcgggcagctggt tcgccgacagcaccaccaagtattccaattttgaaacccgtcctgcacgctacgt gcgcttagtggccgtgacagaggcgaacggccagccatggacctcaatcgccgaa atcaatgtattccaagccagctcctataccgcgccgcagccaggacttgggcgtt ggggcccgaccatcgacctgcctatcgtacccagcgccgcggcgattgaaccaac gtcaggccgcgtactgatgtggagcagctaccgtaacgacgcggcggaaggcagc ccgggcggcatcactctgacgtcgagttgggatccatccacgggcatcgtctccg accgcaccgtgaccgtcacgaaacacgacatgttttgcccggggatcagcatgga cggcaccggccagatcgtcgtcacgggcggctgggacgccaagaagacgagcctc tatgacagtagcagcgacagttggatcccggggccggacatgcaggtggcacgcg ggtaccagtccagcgcgaccatgtcagacggccgtgtctttacaatcggcggctc atttagtggcggagtgtttgagaagaatggcgaagtctatagcccctcatccaaa acgtggacgtcacttccgaacgcgaaggtgtggcccatgttaaccgccgacaaac agggcctgtacatgagcgacaaccatgcgtggctgttcggctggaagaaggggag cgtctttcaggcgggcccgtcgaccgcaatgaattggtattacacgtcaggaagc ggggacgtgaaatcagccggcaagcgccagtcgaaccgcggcgtggcgccggacg caatgtgcggcaatgccgtgatgtatgacgcggtcaaaggcaagatcctgacatt tggcgggagtccggactacaccgacagtgacgcgacaaccaatgcccacattatt acccttggggagccggggacgagcccgaacacggtcttcgcgtccaatggcctct atttcgcgcgtacctttcatacgtcggtggtcctgccggacggatcaacctttat caccggcggacagcgccgtggcatccccttcgaagactcgacccccgtctttaca ccggagatttatgtgccggaacaggacacgttttataaacagaatccgaactcga ttgtacgcgcgtatcactccatcagccttcttctcccggacggacgtgtctttaa tggcggaggaggactgtgcggggactgcacgaccaatcattttgacgcgcagatc tttaccccgaattatctgtatgattcaaatgggaatctcgcgacccgtccgaaaa ttacccgtacatcaacccagtccgtcaaagtgggcggccgcattacgatcagtac cgacagcagcattaccaaagcgtcactgattcgttacggcaccgcaacccataca gtcaacacggaccagcgccgtattccgttaaccctgaccaataacggtggcaatt cgtatagcttccaggtaccgtcggactcgggcgtggcgctgccaggatactggat gctgtttgtgatgaatagcgcgggcgtcccgagcgtagcgagcacgatccgtgtg acccaggccgcagcttgataa 294 GOh3032 MGSSHHHHHHSSGLVPRGSHMGTASAPRGSAIPRNNWAVTCDSAQSGNECNKAID GNKDTFWHTFYGANGDPKPPHTYTIDMKTTQNVNGLSVLPRQDGNQNGWIGRHEV YLSSDGTNWGSPVASGSWFADSTTKYSNFETRPARYVRLVAVTEANGQPWTSIAE INVFQASSYTAPQPGLGRWGPTIDLPIVPSAAAIEPTSGRVLMWSSYRNDAAEGS PGGITLTSSWDPSTGIVSDRTVTVTKHDMFCPGISMDGTGQIVVTGGWDAKKTSL YDSSSDSWIPGPDMQVARGYQSSATMSDGRVFTIGGSFSGGVFEKNGEVYSPSSK TWTSLPNAKVWPMLTADKQGLYMSDNHAWLFGWKKGSVFQAGPSTAMNWYYTSGS GDVKSAGKRQSNRGVAPDAMCGNAVMYDAVKGKILTFGGSPDYTDSDATTNAHII TLGEPGTSPNTVFASNGLYFARTFHTSVVLPDGSTFITGGQRRGIPFEDSTPVFT PEIYVPEQDTFYKQNPNSIVRAYHSISLLLPDGRVFNGGGGLCGDCTTNHFDAQI FTPNYLYDSNGNLATRPKITRTSTQSVKVGGRITISTDSSITKASLIRYGTATHT VNTDQRRIPLTLTNNGGNSYSFQVPSDSGVALPGYWMLFVMNSAGVPSVASTIRV TQAAA 295 GOh3038 atgggcagcagccatcatcatcatcatcacagcagcggcctggtgccgcgcggca gccatatgggtaccgcctctgcccctcgtggctcagccatcccgcgcaataactg ggccgtaacgtgcgacagcgcgcagagcggcaacgagtgcaataaagccatcgac ggcaataaagacaccttctggcacacgttttatggcgcaaatggcgacccgaagc caccgcatacctataccattgacatgaaaaccacccagaatgtgaacgggctgtc cgtgctgccgcgccaggacggcaatcagaacggatggatcggccgtcacgaggta tatttaagctccgacggcaccaactggggatccccggtcgcgtcgggcagctggt tcgccgacagcaccaccaagtattccaattttgaaacccgtcctgcacgctacgt gcgcttagtggccgtgacagaggcgaacggccagccatggacctcaatcgccgaa atcaatgtattccaagccagctcctataccgcgccgcagccaggacttgggcgtt ggggcccgaccatcgacctgcctatcgtacccaccgccgcggcgattgaaccaac gtcaggccgcgtactgatgtggagcagctaccgtaacgacgcggcggaaggcagc ccgggcggcatcactctgacgtcgagttgggatccatccacgggcatcgtctccg accgcaccgtgaccgtcacgaaacacgacatgttttgcccggggatcagcatgga cggcaccggccagatcgtcgtcacgggcggctgggacgccaagaagacgagcctc tatgacagtagcagcgacagttggatcccggggccggacatgcaggtggcacgcg ggtaccagtccagcgcgaccatgtcagacggccgtgtctttacaatcggcggctc atttagtggcggagtgtttgagaagaatggcgaagtctatagcccctcatccaaa acgtggacgtcacttccgaacgcgaaggtgtggcccatgttaaccgccgacaaac agggcctgtacatgagcgacaaccatgcgtggctgttcggctggaagaaggggag cgtctttcaggcgggcccgtcgaccgcaatgaattggtattacacgtcaggaagc ggggacgtgatctcagccggcaagcgccagtcgaaccgcggcgtggcgccggacg caatgtgcggcaatgccgtgatgtatgacgcggtcaaaggcaagatcctgacatt tggcgggagtccggactacaccgacagtgacgcgacaaccaatgcccacattatt acccttggggagccggggacgagcccgaacacggtcttcgcgtccaatggcctct atttcgcgcgtacctttcatacgtcggtggtcctgccggacggatcaacctttat caccggcggacagcgccgtggcatccccttcgaagactcgacccccgtctttaca ccggagatttatgtgccggaacaggacacgttttataaacagaatccgaactcga ttgtacgcgcgtatcactccatcagccttcttctcccggacggacgtgtctttaa tggcggaggaggactgtgcggggactgcacgaccaatcattttgacgcgcagatc tttaccccgaattatctgtatgattcaaatgggaatctcgcgacccgtccgaaaa ttacccgtacatcaacccagtccgtcaaagtgggcggccgcattacgatcagtac cgacagcagcattaccaaagcgtcactgattcgttacggcaccgcaacccataca gtcaacacggaccagcgccgtattccgttaaccctgaccaataacggtggcaatt cgtatagcttccaggtaccgtcggactcgggcgtggcgctgccaggatactggat gctgtttgtgatgaatagcgcgggcgtcccgagcgtagcgagcacgatccgtgtg acccaggccgcagcttgataa 296 GOh3038 MGSSHHHHHHSSGLVPRGSHMGTASAPRGSAIPRNNWAVTCDSAQSGNECNKAID GNKDTFWHTFYGANGDPKPPHTYTIDMKTTQNVNGLSVLPRQDGNQNGWIGRHEV YLSSDGTNWGSPVASGSWFADSTTKYSNFETRPARYVRLVAVTEANGQPWTSIAE INVFQASSYTAPQPGLGRWGPTIDLPIVPTAAAIEPTSGRVLMWSSYRNDAAEGS PGGITLTSSWDPSTGIVSDRTVTVTKHDMFCPGISMDGTGQIVVTGGWDAKKTSL YDSSSDSWIPGPDMQVARGYQSSATMSDGRVFTIGGSFSGGVFEKNGEVYSPSSK TWTSLPNAKVWPMLTADKQGLYMSDNHAWLFGWKKGSVFQAGPSTAMNWYYTSGS GDVISAGKRQSNRGVAPDAMCGNAVMYDAVKGKILTFGGSPDYTDSDATTNAHII TLGEPGTSPNTVFASNGLYFARTFHTSVVLPDGSTFITGGQRRGIPFEDSTPVFT PEIYVPEQDTFYKQNPNSIVRAYHSISLLLPDGRVFNGGGGLCGDCTTNHFDAQI FTPNYLYDSNGNLATRPKITRTSTQSVKVGGRITISTDSSITKASLIRYGTATHT VNTDQRRIPLTLTNNGGNSYSFQVPSDSGVALPGYWMLFVMNSAGVPSVASTIRV TQAAA 297 GOh3049 atgggcagcagccatcatcatcatcatcacagcagcggcctggtgccgcgcggca gccatatgggtaccgcctctgcccctatcggctcagccatcccgcgcaataactg ggccgtaacgtgcgacagcgcgcagagcggcaacgagtgcaataaagccatcgac ggcaataaagacaccttctggcacacgttttatggcgcaaatggcgacccgaagc caccgcatacctataccattgacatgaaaaccacccagaatgtgaacgggctgtc cgtgctgccgcgccaggacggcaatcagaacggatggatcggccgtcacgaggta tatttaagctccgacggcaccaactggggatccccggtcgcgtcgggcagctggt tcgccgacagcaccaccaagtattccaattttgaaacccgtcctgcacgctacgt gcgcttagtggccgtgcgtgaggcgaacggccagccatggacctcaatcgccgaa atcaatgtattccaagccagctcctataccgcgccgcagccaggacttgggcgtt ggggcccgaccatcgacctgcctatcgtacccgcagccgcggcgattgaaccaac gtcaggccgcgtactgatgtggagcagctaccgtaacgacgcggcggaaggcagc ccgggcggcatcactctgacgtcgagttgggatccatccacgggcatcgtctccg accgcaccgtgaccgtcacgaaacacgacatgttttgcccggggatcagcatgga cggcaacggccagatcgtcgtcacgggcggctgggacgccaagaagacgagcctc tatgacagtagcagcgacagttggatcccggggccggacatgcaggtggcacgcg ggtaccagtccagcgcgaccatgtcagacggccgtgtctttacaatcggcggctc atttagtggcggagtgtttgagaagaatggcgaagtctatagcccctcatccaaa acgtggacgtcacttccgaacgcgaaggtgtggcccatgttaaccgccgacaaac agggcctgtacatgagcgacaaccatgcgtggctgttcggctggaagaaggggag cgtctttcaggcgggcccgtcgaccgcaatgaattggtattacacgtcaggaagc ggggacgtgaaatcagccggcaagcgccagtcgaaccgcggcgtggcgccggacg caatgtgcggcaatgccgtgatgtatgacgcggtcaaaggcaagatcctgacatt tggcgggagtccggactacaccgacagtgacgcgacaaccaatgcccacattatt acccttggggagccggggacgagcccgaacacggtcttcgcgtccaatggcctct atttcgcgcgtacctttcatacgtcggtggtcctgccggacggatcaacctttat caccggcggacagcgccgtggcatccccttcgaagactcgacccccgtctttaca ccggagatttatgtgccggaacaggacacgttttataaacagaatccgaactcga ttgtacgcgcgtatcactccatcagccttcttctcccggacggacgtgtctttaa tggcggaggaggactgtgcggggactgcacgaccaatcattttgacgcgcagatc tttaccccgaattatctgtatgattcaaatgggaatctcgcgacccgtccgaaaa ttacccgtacatcaacccagtccgtcaaagtgggcggccgcattacgatcagtac cgacagcagcattaccaaagcgtcactgattcgttacggcaccgcaacccataca gtcaacacggaccagcgccgtattccgttaaccctgaccaataacggtggcaatt cgtatagcttccaggtaccgtcggactcgggcgtggcgctgccaggatactggat gctgtttgtgatgaatagcgcgggcgtcccgagcgtagcgagcacgatccgtgtg acccaggccgcagcttgataa 298 GOh3049 MGSSHHHHHHSSGLVPRGSHMGTASAPIGSAIPRNNWAVTCDSAQSGNECNKAID GNKDTFWHTFYGANGDPKPPHTYTIDMKTTQNVNGLSVLPRQDGNQNGWIGRHEV YLSSDGTNWGSPVASGSWFADSTTKYSNFETRPARYVRLVAVREANGQPWTSIAE INVFQASSYTAPQPGLGRWGPTIDLPIVPAAAAIEPTSGRVLMWSSYRNDAAEGS PGGITLTSSWDPSTGIVSDRTVTVTKHDMFCPGISMDGNGQIVVTGGWDAKKTSL YDSSSDSWIPGPDMQVARGYQSSATMSDGRVFTIGGSFSGGVFEKNGEVYSPSSK TWTSLPNAKVWPMLTADKQGLYMSDNHAWLFGWKKGSVFQAGPSTAMNWYYTSGS GDVKSAGKRQSNRGVAPDAMCGNAVMYDAVKGKILTFGGSPDYTDSDATTNAHII TLGEPGTSPNTVFASNGLYFARTFHTSVVLPDGSTFITGGQRRGIPFEDSTPVFT PEIYVPEQDTFYKQNPNSIVRAYHSISLLLPDGRVFNGGGGLCGDCTTNHFDAQI FTPNYLYDSNGNLATRPKITRTSTQSVKVGGRITISTDSSITKASLIRYGTATHT VNTDQRRIPLTLTNNGGNSYSFQVPSDSGVALPGYWMLFVMNSAGVPSVASTIRV TQAAA