PERIODONTAL TISSUE REGENERATION INDUCER AND APPARATUS AND METHOD FOR MANUFACTURING THE SAME

Abstract

A periodontal tissue regeneration inducer and an apparatus and a method for manufacturing the same are provided. The periodontal tissue regeneration inducer includes a sheet body formed of a flexible material, and a pattern layer having a pattern formed therein to facilitate bone formation or regeneration on a surface of the sheet body. Therefore, the periodontal tissue regeneration inducer and the apparatus and method for manufacturing the same have an advantage in that the bone formation or regeneration may be facilitated during implant surgery because the membrane sheet is composed of a polycaprolactone (PCL) material and a nanopattern is formed on a surface of the pattern layer.

Claims

1. A method for manufacturing a periodontal tissue regeneration inducer, comprising: a coating step of coating glass with a polymer to a predetermined thickness; a pattern molding step of molding a pattern by pressing the coated polymer with a patterned mold; and a separation step of separating the polymer from the glass after the pattern molding step.

2. The method of claim 1, wherein the coating step comprises putting the polymer on the glass and spin-coating the glass while rotating the glass.

3. The method of claim 1, further comprising a planarization step of planarizing a surface of the coated polymer between the coating step and the pattern molding step, wherein the planarization step comprises: a primary heating step of heating the coated polymer; a primary in-mold molding step of molding the heated polymer by pressing a surface of the heated polymer with a flat mold; and a primary cooling step of cooling the molded polymer, and wherein the pattern molding step comprises: a secondary heating step of heating the coated polymer; a secondary in-mold molding step of molding the heated polymer by pressing the heated polymer with a patterned mold; and a secondary cooling step of cooling the molded polymer.

4. The method of claim 3, wherein the primary cooling step comprises cooling the planarized polymer by spraying air onto the glass.

5. The method of claim 1, wherein the separation step further comprises: separating the polymer from the glass by immersing the glass coated with the polymer in ethanol, and a drying step of drying the separated polymer.

Description

BRIEF DESCRIPTION OF THE DRAWINGS

[0025] The above and other objects, features and advantages of the present invention will become more apparent to those of ordinary skill in the art by describing in detail exemplary embodiments thereof with reference to the attached drawings, in which:

[0026] FIG. 1 is a diagram showing a periodontal tissue regeneration inducer according to one preferred embodiment of the present invention;

[0027] FIG. 2 is a block diagram showing a method for manufacturing a periodontal tissue regeneration inducer according to one preferred embodiment of the present invention;

[0028] FIG. 3 is a conceptual diagram showing the method for manufacturing a periodontal tissue regeneration inducer according to one preferred embodiment of the present invention;

[0029] FIG. 4 is a perspective view showing an apparatus for manufacturing a periodontal tissue regeneration inducer according to one preferred embodiment of the present invention;

[0030] FIG. 5 is a front view showing the apparatus for manufacturing a periodontal tissue regeneration inducer according to one preferred embodiment of the present invention;

[0031] FIG. 6 is a partially exploded perspective view showing the apparatus for manufacturing a periodontal tissue regeneration inducer according to one preferred embodiment of the present invention;

[0032] FIG. 7 is an exploded perspective view showing a pattern molding unit and a support unit of the apparatus for manufacturing a periodontal tissue regeneration inducer according to one preferred embodiment of the present invention; and

[0033] FIG. 8 is an exploded perspective view showing a coupling plate and a mold fixing member according to one preferred embodiment of the present invention.

DETAILED DESCRIPTION OF EXEMPLARY EMBODIMENTS

[0034] Hereinafter, “periodontal tissue regeneration inducer and apparatus and method for manufacturing the same” according to one exemplary embodiment of the present invention will be described in detail with reference to the accompanying drawings. The present invention may be modified into various forms and may have various embodiments, and specific embodiments thereof will be illustrated in the drawings and described herein in detail. However, it should be understood that the description set forth herein is not intended to limit the particular embodiments of the present invention, and encompasses all modifications, equivalents, and substitutions that fall within the spirit and scope of the present invention. Throughout the description of the figures, like numbers refer to like elements. In the accompanying drawings, the dimensions of parts are shown to be more exaggerated than they actually are for clarity of the present invention.

[0035] Although the terms first, second, etc. may be used to describe various elements, these elements are not limited by these terms. These terms are only used to distinguish one element from another. For example, a first element could be termed a second element, and, similarly, a second element could be termed a first element, without departing from the scope of the present invention.

[0036] The terminology used herein is for the purpose of describing particular embodiments only and is not intended to limit the present invention. The singular forms “a,” “an” and “the” are intended to include the plural forms as well, unless the context clearly indicates otherwise. It will be further understood that the terms “comprises,” “comprising,” “includes” and/or “including,” when used herein, specify the presence of stated features, integers, steps, operations, elements, components and/or groups thereof, but do not preclude the presence or addition of one or more other features, integers, steps, operations, elements, components and/or groups thereof.

[0037] Unless otherwise defined, all terms (including technical and scientific terms) used herein have the same meaning as commonly understood by one of ordinary skill in the art to which this invention belongs. It will be further understood that the terms, such as those defined in commonly used dictionaries, should be interpreted as having a meaning that is consistent with their meaning in the context of the relevant art and will not be interpreted in an idealized or overly formal sense unless expressly so defined herein.

[0038] Referring to FIG. 1, a periodontal tissue regeneration inducer according to one exemplary embodiment of the present invention includes a sheet body 100 and a pattern layer 200.

[0039] The sheet body 100 is preferably formed of a flexible material so that the sheet body 100 can be attached to the bone during implant surgery. The pattern layer 200 has a pattern formed therein to facilitate bone formation or regeneration on a surface of the sheet body 100.

[0040] The sheet body 100 and pattern layer 200 are composed of a polycaprolactone (PCL) material and have a nanopattern formed on a surface thereof. According to one exemplary embodiment of the present invention, the PCL material is applied, but the present invention is not limited thereto. For example, various materials such as polyglycolic acid (PGA), polylactic acid (PLA), poly-lactic-co-glycolic acid (PLGA), poly(L-lactic acid) (PLLA), and the like may be applied as the PCL material.

[0041] Referring to FIGS. 2 and 3, a method for manufacturing a periodontal tissue regeneration inducer according to one exemplary embodiment of the present invention includes a coating step S100, a planarization step S200, a pattern molding step S300, a separation step S400, and a drying step S500.

[0042] In the coating step S100, glass 310 is coated with a polymer 300 to a predetermined thickness. In the coating step S100, the polymer 300 is put on the glass 310, and the glass 310 is then spin-coated while rotating the glass 310.

[0043] In the planarization step S200, a surface of the polymer is planarized. For this purpose, the planarization step S200 includes a primary heating step S210, a primary in-mold molding step S220, and a primary cooling step S230.

[0044] In the primary heating step S210, the coated polymer 300 is heated. In the primary in-mold molding step S220, the polymer 300 heated in the primary heating step S210 is molded by pressing a surface of the polymer 300 with a flat mold 320.

[0045] In the primary cooling step S230, the polymer 300 is cooled so that the polymer whose surface is planarized by pressing with the flat mold 320 can be separated from the mold. In the primary cooling step S230, the planarized polymer 300 is cooled by spraying air onto the glass 310.

[0046] In the pattern molding step S300, a pattern is molded by pressing the coated polymer 300 with a patterned mold 330. For this purpose, the pattern molding step S300 includes a secondary heating step S310, a secondary in-mold molding step S320, and a secondary cooling step S330.

[0047] In the secondary heating step S310, the coated polymer 300 is heated. In the secondary in-mold molding step S320, the heated polymer 300 is molded by pressing the heated polymer 300 with the patterned mold 330. In this case, the pattern preferably consists of a nanopattern. In the secondary cooling step S330, the molded polymer 300 is cooled.

[0048] In the separation step S400, the polymer 300 is separated from the glass 310 after the pattern molding step S300. In the separation step S400, the polymer 300 is separated from the glass 310 by immersing the glass 310 coated with the polymer 300 in ethanol.

[0049] In the drying step S500, the polymer 300 immersed in the ethanol is dried. In the drying step S500, the polymer 300 is dried by natural drying. Finally, a periodontal tissue regeneration inducer of the present invention is manufactured.

[0050] Referring to FIGS. 4 to 7, an apparatus 10 for manufacturing a periodontal tissue regeneration inducer according to one exemplary embodiment of the present invention includes a holder 400, a frame 500, a pattern molding unit 600, a support unit 700, and a transfer unit 800.

[0051] The holder 400 is configured to allow a user to manipulate and control the apparatus 10 for manufacturing a periodontal tissue regeneration inducer. In this case, a control panel 410 is provided on one side of the holder 400. The frame 500 is installed on the holder 400, and is then formed so that the frame 500 is coupled to the pattern molding unit 600.

[0052] The pattern molding unit 600 is configured to mold a pattern by pressing the polymer 300 with which the glass 310 is coated. In this case, the pattern molding unit 600 is installed on the frame 500 to move in a vertical direction, and includes a first molding part 610 and a second molding part 620.

[0053] The first molding part 610 is configured to planarize polymer 300 on the glass 310. The second molding part 620 is configured to mold a pattern onto the planarized polymer 300, and is installed side by side with the first molding part 610 so that the second molding part 620 is adjacent to the first molding part 610.

[0054] Each of the first molding part 610 and the second molding part 620 includes an actuator 612, a mold coupling part 614, and a molding mold 618.

[0055] The actuator 612 is a pneumatic cylinder that operates with hydraulic pressure or pneumatic pressure, and is generally configured to provide a mechanical operation so that the pressure is applied to the polymer 300, and thus a detailed description thereof is omitted for clarity.

[0056] The mold coupling part 614 is formed to move in a vertical direction by the actuator 612, and includes a coupling plate 615 and a mold fixing member 616.

[0057] The coupling plate 615 is coupled to the actuator 612, and has a sliding groove 617 formed therein.

[0058] The mold fixing member 616 has a mold hole 619 formed therein to expose a surface of the molding mold 618 to the polymer 300, and is coupled to the coupling plate 615 to support the molding mold 618. Therefore, the mold fixing member 616 is detachably installed in the coupling plate 615. The mold fixing member 616 is attachable or detachable because the mold fixing member 616 is formed to be pulled in/drawn out along the sliding groove 617 of the coupling plate 615.

[0059] The molding mold 618 is provided in the mold coupling part 614. The first molding mold 618 of the first molding part 610 has a flat surface formed therein. A nanopattern is formed on a surface of the second molding mold 618 of the second molding part 620. The molding mold 618 according to one exemplary embodiment of the present invention has a flat surface or has a nanopattern formed on a surface thereof, but the present invention is not limited thereto. For example, patterns with various shapes are applicable to the molding mold 618.

[0060] The support unit 700 is installed below the pattern molding unit 600, and is configured to support the glass 310 and heat and cool the polymer 300 in order to mold the polymer 300. For this purpose, the support unit 700 includes a support plate 710, a hot plate 720, and an air supply part.

[0061] The support plate 710 is configured to support the hot plate 720. In this case, the support plate 710 is preferably made of a resin having high durability to withstand the heat generated by the hot plate 720.

[0062] The hot plate 720 is installed with the glass 310 coated with the polymer 300, and is configured to indirectly supply a heat source to the glass 310. In this case, the hot plate 720 is installed on the support plate 710.

[0063] Although not shown in the drawings, the air supply part is configured to supply air in order to cool the polymer 300 with which the glass 310 is coated, and includes an air nozzle and a connection hose.

[0064] The air nozzle is installed at the support plate 710, and is configured to spray air onto the hot plate 720 or the glass 310 coated with the polymer 300. The connection hose is connected to the air nozzle to supply air.

[0065] Therefore, the air flowing from the outside through the connection hose is supplied to the air nozzle. Then, the supplied air is sprayed through the air nozzle to cool the hot plate 720 or the glass 310. As a result, the polymer 300 is hardened.

[0066] The transfer unit 800 is configured to transfer the support unit 700 to face the pattern molding unit 600, and includes a guide rail 810, a driving part 820, a fixed rail 830, and a fixed driving part 840.

[0067] The guide rail 810 is formed to extend in a horizontal direction. In this case, one or more guide rails are installed on the holder 400 to face the first molding part 610 and the second molding part 620 of the pattern molding unit 600. A metal material is preferably used in the guide rail 810.

[0068] The driving part 820 is driven along the guide rail 810. In this case, the driving part 820 is configured to support the support plate 710 and is installed to be driven along the guide rail 810.

[0069] One or more fixed rails 830 are installed on the holder 400 to be side by side with the guide rail 810. The fixed driving part 840 is configured to fix the driving part 820, and is driven along the fixed rail 830. Also, the fixed driving part 840 is arranged to face the driving part 820, and is configured to fix the driving part 820.

[0070] An operation of the apparatus 10 for manufacturing a membrane sheet according to one exemplary embodiment of the present invention is as follows.

[0071] First, when a user installs the glass 310 coated with the polymer 300 on the hot plate 720, the polymer 300 is melted by the hot plate 720. At the same time, the driving part 820 is driven along the guide rail 810 to face the first molding part 610.

[0072] In this case, the polymer 300 is planarized by pressing the polymer 300 arranged on the polymer 300 with the first molding mold 618 of the first molding part 610. At the same time, after an operation of the hot plate 720 of the support unit 700 is stopped, the molten polymer 300 arranged on the glass 310 is hardened, and the first molding part 610 is spaced apart from the polymer 300. As a result, this planarization process is completed.

[0073] Then, the hardened polymer 300 on the glass 310 is melted by the hot plate 720 of the support unit 700. At the same time, the driving part 820 is driven along the guide rail 810 to face the second molding part 620.

[0074] In this case, a nanopattern is formed by pressing the polymer 300 arranged on the glass 310 with the second molding mold 618 of the second molding part 620. At the same time, after an operation of the hot plate 720 is stopped, the molten polymer 300 arranged on the glass 310 is hardened, the second molding part 620 is spaced apart from the polymer 300, and a nanopattern is formed on the polymer 300. The polymer 300 on which the nanopattern is formed is finally separated from the glass 310. As a result, the periodontal tissue regeneration inducer according to the present invention is manufactured.

[0075] The periodontal tissue regeneration inducer according to the present invention and the apparatus and method for manufacturing the same have an advantage in that bone formation or regeneration cab be facilitated during implant surgery because the membrane sheet is composed of a polycaprolactone (PCL) material and a nanopattern is formed on the pattern layer.

[0076] The description of the presented embodiments is provided so that those skilled in the art to which the present invention belongs use or implement the present invention. It will be apparent to those skilled in the art that various changes and modifications can be made to these embodiments, and that general principles defined herein can be applied to other embodiments without departing from the scope of the present invention. Therefore, the present invention is not limited to the embodiments presented herein, but should be interpreted within the widest range which is associated with the principles and new features presented herein.

TABLE-US-00001 [Brief Description of Main Parts in the Drawings]    10: apparatus for manufacturing a periodontal tissue regeneration  100: sheet body  200: pattern layer  300: polymer  310: glass  320: flat mold  330: patterned mold  400: holder  410: control panel  500: frame  600: pattern molding unit  610: first molding part  612: actuator  614: mold coupling part  615: coupling plate  616: mold fixing member  617: sliding groove  618: molding mold  619: mold hole  620: second molding part  700: support unit  710: support plate  720: hot plate  800: transfer unit  810: guide rail  820: driving part  830: fixed rail  840: fixed driving part S100: coating step S200: planarization step S210: primary heating step S220: primary in-mold molding step S230: primary cooling step S300: pattern molding step S310: secondary heating step S320: secondary in-mold molding step S330: secondary cooling step S400: separation step S500: drying step