Pump-type toothpaste composition

Abstract

The present disclosure relates to a pump-type toothpaste composition which can be provided by being comprised in a pump-type container, and particularly, relates to a pump-type toothpaste composition with improved feeling of use when brushing teeth. In addition, the present disclosure relates to a pump toothpaste composition having improved tailing and dry-hardening property. The pump-type toothpaste composition of the present disclosure may comprise a hydrocolloid.

Claims

1. A pump-type toothpaste composition comprised in a pump-type container, comprising a substantially non-hydrated hydrocolloid and water, wherein the weight ratio of the substantially non-hydrated hydrocolloid and water is 0.5-10:1 (substantially non-hydrated hydrocolloid:water), wherein the hydrocolloid is xanthan gum; or the hydrocolloid is one or more selected from the group consisting of agarose, agar, cellulose, dextrin, gelatin, Japanese agar, pectin, starch, chemically modified starch, carboxymethyl cellulose, methyl cellulose, sodium carboxymethyl cellulose, hydroxypropylmethyl cellulose, hydroxymethyl cellulose, hydroxyethyl cellulose, methylhydroxypropyl cellulose, carbomer, galactomannan, glucomannan, locust bean gum, gellan gum, gum karaya, gum Arabic, gum tragacanth, guar gum, and alginate, wherein the content of the substantially non-hydrated hydrocolloid is 3 to 6% by weight based on the total weight of the composition, and wherein the pump-type toothpaste composition further comprises 0.1 to 50% by weight of an abrasive and 1 to 20% by weight of a foaming agent, based on the total weight of the composition.

2. The pump-type toothpaste composition according to claim 1, wherein the viscosity of the pump-type toothpaste composition is 4,000 cP to 35,000 cP.

3. The pump-type toothpaste composition according to claim 1, wherein the content of the water is less than 5% by weight based on the total weight of the composition.

4. The pump-type toothpaste composition according to claim 1, wherein the viscosity becomes increased 1.1 to 2 times when mixing 10 g of the pump-type toothpaste composition and 1 ml of water, compared to the viscosity of the composition before mixing.

5. The pump-type toothpaste composition according to claim 1, wherein the pump-type toothpaste composition is in a gel phase.

6. Pump-type toothpaste comprising the pump-type toothpaste composition according to claim 1, and a pump-type container in which the pump-type toothpaste composition is comprised.

7. A pump-type toothpaste composition comprised in a pump-type container, comprising an acrylic polymer, a hydrocolloid, and an abrasive, wherein the acrylic polymer is uncross-linked, wherein the hydrocolloid is substantially non-hydrated hydrocolloid, wherein the pump-type toothpaste composition is in a gel phase, and wherein the abrasive is selected from the group consisting of calcium monohydrogen phosphate, precipitated silica, fumed silica, hydrated silicon dioxide, colloidal silicon dioxide, silica gel, zeolite, calcium carbonate, hydrated alumina, kaolin, cellulose and a mixture thereof, wherein the content of the substantially non-hydrated hydrocolloid is 3 to 6% by weight based on the total weight of the composition, wherein the hydrocolloid is xanthan gum; or the hydrocolloid is one or more selected from the group consisting of agarose, agar, cellulose, dextrin, gelatin, Japanese agar, pectin, starch, chemically modified starch, carboxymethyl cellulose, methyl cellulose, sodium carboxymethyl cellulose, hydroxypropylmethyl cellulose, hydroxymethyl cellulose, hydroxyethyl cellulose, methylhydroxypropyl cellulose, carbomer, galactomannan, glucomannan, locust bean gum, gellan gum, gum karaya, gum Arabic, gum tragacanth, guar gum, and alginate, and wherein the pump-type toothpaste composition comprises 0.05 to 1.0% by weight of the acrylic polymer.

8. The pump-type toothpaste composition according to claim 7, wherein the acrylic polymer is a polyacrylic polymer, polymethacrylic polymer, polyalkylacrylic polymer or polyalkylmethacrylic polymer.

9. The pump-type toothpaste composition according to claim 7, wherein the acrylic polymer is prepared by polymerizing one or more of monomers selected from the group consisting of acrylate, methacrylate, alkyl acrylate, alkyl methacrylate, hydroxyalkyl acrylate, hydroxyalkyl methacrylate, diethylene glycol acrylate, diethylene glycol methacrylate, acrylamide, methacrylamide, diacetone acrylamide, methylol acrylamide and methylol methacrylate.

10. The pump-type toothpaste composition according to claim 7, wherein the weight ratio of the acrylic polymer to the substantially non-hydrated hydrocolloid is 0.05 to 20.

11. The pump-type toothpaste composition according to claim 1, wherein the pump-type toothpaste composition further comprises one or more selected from an abrasive, a lubricant, a flavoring agent, a sweetener, a pharmaceutical agent, a pH adjusting agent, a preservative, a foaming agent and a whitening agent.

12. The pump-type toothpaste composition according to claim 7, wherein the pump-type toothpaste composition has at least 50% reduced length of tail of the toothpaste composition dragging from a discharge port after pumping, compared to a case of not comprising an acrylic polymer.

13. The pump-type toothpaste composition according to claim 7, wherein the pump-type toothpaste composition has a strain rate of at least 1.0% and a recovery rate of at least 40%, when applying a force of 4 Pa.

14. The pump-type toothpaste composition according to claim 7, wherein the pump-type toothpaste composition is in a gel phase.

15. The pump-type toothpaste composition according to claim 7, wherein the pump-type toothpaste composition further comprises one or more selected from an abrasive, a lubricant, a flavoring agent, a sweetener, a pharmaceutical agent, a pH adjusting agent, a preservative, a foaming agent and a whitening agent.

Description

DETAILED DESCRIPTION OF THE EMBODIMENTS

(1) Hereinafter, in order to help understanding of the present disclosure, it will be described in detail by examples, and the like. However, the examples according to the present disclosure may be modified into various other forms, and the scope of the present disclosure should not be construed to be limited by the following examples. The examples of the present disclosure are provided to illustrate the present disclosure to those skilled in the art more completely.

(2) I. Preparative Example A of Pump-Type Toothpaste Composition

(3) Preparation of Examples A1-A6 and Comparative Examples A1-A3

(4) Toothpaste compositions of Examples and Comparative examples were prepared by components and weights shown in the following Table 1. Toothpaste compositions were prepared by completely distributing purified water, glycerin, a flavoring, a pharmaceutical agent, a surfactant, a hydrocolloid, and powder components such as sodium saccharin, and the like and primarily mixing them, and then adding an abrasive such as precipitated silica, and the like, and other components and mixing them under a vacuum condition.

(5) TABLE-US-00001 TABLE 1 Comparative Comparative Comparative Example Example Example Example Example Example example example example A1 A2 A3 A4 A5 A6 A1 A2 A3 Precipitated 15.00 15.00 15.00 15.00 15.00 15.00 15.00 15.00 15.00 silica Glycerin 74.00 73.00 72.00 71.00 71.00 71.00 75.00 74.00 74.00 Sodium 2.00 2.00 2.00 2.00 2.00 2.00 2.00 2.00 2.00 lauryl sulfate Sodium 0.20 0.20 0.20 0.20 0.20 0.20 0.20 0.20 0.20 saccharin Cellulose 3.00 4.00 5.00 3.00 3.00 3.00 1.00 1.00 gum Acrylic 3.00 1.00 polymer Xanthan 3.00 2.00 1.00 1.50 2.50 gum Sodium 0.22 0.22 0.22 0.22 0.22 0.22 0.22 0.22 0.22 fluoride Vitamin E 0.20 0.20 0.20 0.20 0.20 0.20 0.20 0.20 0.20 Flavoring 1.00 1.00 1.00 1.00 1.00 1.00 1.00 1.00 1.00 Purified 4.38 4.38 4.38 4.38 4.38 4.38 4.38 4.88 4.88 water

(6) Experiment 1. Evaluation of Dry-Hardening of Toothpaste

(7) After filling Examples and Comparative examples prepared above in 24 well plates, they were dried in a dried oven furnace of 60° equipped with a fan for 48 hours. Then, dry-hardening of toothpaste was evaluated as dry-hardening when applying pressure using a probe, and the result was shown in Table 2. The degree of dry-hardening so that there was no mark on contents was represented as hardened, and the case that there were scratches on contents or the probe entered into contents was represented as not hardened.

(8) TABLE-US-00002 TABLE 2 Comparative Comparative Comparative Example Example Example Example Example Example example example example A1 A2 A3 A4 A5 A6 A1 A2 A3 Degree of Not Not Not Not Not Not Not Not Not hardening hardened hardened hardened hardened hardened hardened hardened hardened hardened

(9) Experiment 2. Viscosity Measurement

(10) The viscosity of the toothpaste compositions prepared above at 20 rpm using Brookfield Viscometer No. 5 spindle, and the result was shown in Table 3. The initial viscosity was measured after stabilizing the prepared toothpaste for 2 days, and the dilution viscosity was measured after adding purified water of 10% by weight based on the weight of the composition to the toothpaste composition stabilized for 2 days.

(11) TABLE-US-00003 TABLE 3 Comparative Comparative Comparative Example Example Example Example Example Example example example example A1 A2 A3 A4 A5 A6 A1 A2 A3 Initial 20,000 20,000 20,000 25,000 30,000 30,000 20,000 25,000 30,000 viscosity (cP) Dilution 22,000 28,000 33,000 50,000 45,000 55,000 15000 20,000 25,000 viscosity (cP)

(12) Result

(13) Examples A1-A6 and Comparative examples A1-A3 were not hardened all, and the initial viscosity was 20,000-30,000 cP, and all had improved dry-hardening phenomena when discharging and were desirable for easiness of discharging, as a pump-type toothpaste composition. However, for the dilution viscosity, it was confirmed that it was increased compared to the initial viscosity in Examples A1-A6, and it was reduced in Comparative examples A1-A3. Accordingly, it was confirmed that when applying the toothpaste composition of the present disclosure, the viscosity of the toothpaste was increased when brushing teeth, and therefore it could provide rich feeling of use despite of dilution of the toothpaste.

(14) II. Preparative example B of pump-type toothpaste composition

(15) Toothpaste compositions of Examples and Comparative examples were prepared by components and weights shown in the following Table 4. Toothpaste compositions were prepared by completely distributing purified water, liquid polyol, a flavoring, a pharmaceutical agent, a surfactant, a co-bonding agent with acrylate, saccharin, a preservative, and powder components such as a surfactant, and the like and primarily mixing them, and then adding an abrasive such as silica, and the like, and a pharmaceutical agent and mixing them under a vacuum condition.

(16) TABLE-US-00004 TABLE 4 Example Example Example Example Example Example Example Example Example Example Example Comparative Comparative B1 B2 B3 B4 B5 B6 B7 B8 B9 B10 B11 example B1 example B2 Precipitated 15 15 15 15 15 15 15 15 15 15 15 15 15 silica Glycerin 50 50 50 50 50 50 50 50 50 50 50 50 50 Sodium 2.2 2.2 2.2 2.2 2.2 2.2 2.2 2.2 2.2 2.2 2.2 2.2 2.2 lauryl sulfate Sodium 0.2 0.2 0.2 0.2 0.2 0.2 0.2 0.2 0.2 0.2 0.2 0.2 0.2 saccharin Sodium 0.22 0.22 0.22 0.22 0.22 0.22 0.22 0.22 0.22 0.22 0.22 0.22 0.22 fluoride Vitamin 0.2 0.2 0.2 0.2 0.2 0.2 0.2 0.2 0.2 0.2 0.2 0.2 0.2 E Sodium 0.1 0.1 0.2 0.1 0.1 hydroxide Polyacrylate 0.05 0.5 1 0.5 0.5 Sodium polyacrylate 0.05 0.5 1 0.5 0.5 0.5 1 Sodium 0.5 0.5 0.2 1 carboxy methyl cellulose Xanthan 1 0.5 0.05 1 0.5 0.05 0.5 gum Sodium 0.5 0.5 alginate Flavoring 1 1 1 1 1 1 1 1 1 1 1 1 1 Purified 30.03 30.08 29.93 30.08 30.08 30.13 30.18 30.13 30.18 30.18 29.98 30.18 30.18 water

(17) Experiment 1: Evaluation of Phase Stability of Prepared Toothpaste

(18) For the toothpaste prepared as Examples B1˜B11 and Comparative examples B1˜B2 of Table 4, the phase stability was evaluated using evaluation criteria of phase separation, liquid separation, lumping, and uniformity of toothpaste, and the result was shown in Table 5.

(19) TABLE-US-00005 TABLE 5 Example Example Example Example Example Example Example Example Example Example Example Comparative Comparative B1 B2 B3 B4 B5 B6 B7 B8 B9 B10 B11 Example B1 Example B2 Viscosity Good Good Good Good Good Good Good Good Good Good Good Poor Good (1000 cP)

(20) As confirmed in the Table 5, it was shown that when using only the acrylate polymer, the internal solids were agglomerated to push out liquid components in prescription, resulting in phase separation, and therefore the stability was poor.

(21) Experiment 2: Tailing Measurement (Tailing Length Measurement)

(22) The tailing length was evaluated by the method of measuring the residual length remaining in a discharging port after discharging pump toothpaste, and the result was shown in the following Table 6.

(23) TABLE-US-00006 TABLE 6 Example Example Example Example Example Example Example Example Example Example Example Comparative Comparative B1 B2 B3 B4 B5 B6 B7 B8 B9 B10 B11 Example B1 Example B2 Tailing 4 3 2 2 2 4 3 2 2 2 2 — 10 (mm)

(24) As the result of the experiment, it was confirmed that the residual length was good but the stability was not secured and therefore it was not usable when using the acrylate polymer only; and the length was 10mm and thus at least 50% or more of tailing property of the toothpaste was reduced when not using acrylate.

(25) Experiment 3: Evaluation of Recovery Rate of Pump Toothpaste

(26) The strain rate and recovery rate were evaluated when applying a force of 4 Pa using a rheometer, and the result was shown in the following Table 7.

(27) TABLE-US-00007 TABLE 7 Example Example Example Example Example Example Example Example Example Example Example Comparative Comparative B1 B2 B3 B4 B5 B6 B7 B8 B9 B10 B11 Example B1 Example B2 Strain 3 2 1.5 2 2 3 2 1.5 2 2 1.3 — 4 rate (%) Recovery 42 55 70 53 53 44 55 68 52 54 66 — 33 rate (%)

(28) Comparative example B1 had a problem in stability, and therefore it was not measured, and it was confirmed that the recovery rate was poor when using a single hydrocolloid as Comparative example B2.

(29) Experiment 4: Measurement of Drying Speed of Pump Toothpaste

(30) Test method: After filling toothpaste in 24 well plates, it was dried in a dry oven equipped with a fan at 60° C. for 6 hours, and then the degree of dry-hardening of toothpaste was evaluated when applying pressure using a probe (round pen), and the result was shown in the following Table 8.

(31) The rating scale was as follows:

(32) Hardened: The toothpaste becomes hardened to leave no marks thereon

(33) Not hardened: There are scratches on the toothpaste or the probe enters into the toothpaste

(34) TABLE-US-00008 TABLE 8 Exam- Exam- Exam- Exam- Exam- Exam- Exam- ple Example ple Example ple Example ple Example ple ple ple Comparative Comparative B1 B2 B3 B4 B5 B6 B7 B8 B9 B10 B11 Example B1 Example B2 Strain Not Not Not Not Not Not Not Not Not Not Not — Hardened rate hard- hardened hard- hardened hard- hardened hard- hardened hard- hard- hard- (%) ened ened ened ened ened ened ened

(35) Comparative example B1 had a problem in stability, and therefore it was not measured, and it was confirmed that Comparative example B2 was hardened, while the compositions of Examples B1˜B11 had significantly improved dry-hardening.