UV-LASER-BASED SYSTEM FOR CORRECTING VISION DISORDERS
20230201036 · 2023-06-29
Inventors
Cpc classification
A61F9/00814
HUMAN NECESSITIES
International classification
Abstract
A focusing optical system for a UVL-LVC system with a UV laser source and a scanning system that focuses a laser in a focal field and a lens assembly with a convergent focal field. The invention further includes a planning unit that generates planning data for a UVL-LNC system with a UV laser source, a scanning system, a focusing optical system, and a control unit for controlling the UVL-LVC system while taking into consideration planning data, wherein the planning unit takes into consideration geometry losses, Fresnel losses, and/or a spatial extension of laser radiation on a working surface while calculating the planning data, and the planning unit has an interface that provides the planning data. Finally, the invention includes a UVL-LVC system with a UV laser source, a scanning system, a focusing optical system according to the invention, a planning unit according to the invention, and a control unit.
Claims
1.-13. (canceled)
14. A focusing optical unit for a UV laser-based system for vision correction (UVL-LVC system), the UVL-LVC system having a UV laser source that provides laser radiation; and a scanning system that laterally scans the laser radiation in x- and y-directions: wherein the focusing optical unit is configured to focus the laser radiation in a focal field; and wherein the focusing optical unit comprises a first lens arrangement which is configured to provide a convergent focal field.
15. The focusing optical unit as claimed in claim 14, wherein the scanning system that laterally scans the laser radiation in the x- and y-directions also scans the laser radiation in a z-direction.
16. The focusing optical unit as claimed in claim 14, wherein the convergent focal field has a focal field diameter selected from a group consisting of at least 6 mm, at least 8 mm and at least 10 mm.
17. The focusing optical unit as claimed in claim 14, wherein each location in the convergent focal field has a local center of curvature on a side facing away from the focusing optical unit.
18. The focusing optical unit as claimed in claim 17, wherein each location in the focal field has a focal field curvature selected from a group consisting of a radius RS ranging from 8 mm to 50 mm, from 10 mm to 30 mm and from 12 mm to 20 mm.
19. A focusing optical unit for a UV laser-based system for vision correction (UVL-LVC system), the focusing optical unit comprising: a UV laser source that provides laser radiation; and a scanning system that laterally scans the laser radiation in x- and y-directions; wherein the focusing optical unit comprises a lens arrangement that provides perpendicular incidence of laser radiation on a curved surface, wherein each location on the curved surface has a local center of curvature on a side facing away from the focusing optical unit.
20. The focusing optical unit as claimed in claim 19, wherein the curved surface has a diameter selected from a group consisting of at least 6 mm, at least 8 mm and at least 10 mm.
21. The focusing optical unit as claimed in claim 19, wherein the curved surface has a surface curvature with a radius R.sub.F selected from a group consisting of a range from 8 mm to 50 mm, a range from 10 mm to 30 mm and a range from12 mm to 20 mm.
22. The focusing optical unit as claimed in claim 14, configured to have a working distance (Δ) in a range from 20 mm to 50 mm; an optical aperture selected from a group consisting of greater than 40 mm, greater than 50 mm, and greater than or equal to 60 mm, or a combination of the foregoing.
23. The focusing optical unit as claimed in claim 14, comprising a first lens which has a first lens material with a first refractive index and a first Abbe number and comprising a second lens which has a second lens material with a second refractive index and a second Abbe number, with the first refractive index differing from the second refractive index and the first Abbe number differing from the second Abbe number.
24. The focusing optical unit as claimed in claim 23, wherein the first lens has a negative optical power, the second lens has a positive optical power and the first refractive index is greater than the second refractive index.
25. The focusing optical unit as claimed in claim 14, wherein the focusing optical unit has at least two lens groups along a beam path with a non-imaging optical element being arranged therebetween.
26. A planning unit for generating planning data for a UV laser-based system for vision correction (UVL-LVC system), the UVL-LVC system comprising: a UV laser source that provides laser radiation; a scanning system that laterally scans the laser radiation in x- and y-directions; a focusing optical unit that directs the laser radiation to a work surface; and a control unit that controls the UVL-LVC system that is configured to take planning data into consideration; wherein the planning unit is configured to take account of: geometry losses, Fresnel losses, a spatial extent of the laser radiation in the work surface or a combination of the foregoing when calculating the planning data; and wherein the planning unit has an interface operably coupled to the control unit, by which the planning data can be made available to the control unit wherein the focusing optical unit: focuses the laser radiation in a focal field; and wherein the focusing optical unit further comprises a first lens arrangement which is configured to provide a convergent focal field; or wherein the focusing optical unit comprises a second lens arrangement that provides perpendicular incidence of laser radiation on a curved surface, wherein each location on the curved surface has a local center of curvature on a side facing away from the focusing optical unit.
27. (canceled)
28. The planning unit as claimed in claim 26, wherein the focusing optical unit includes the first lens arrangement configured to provide the convergent focal field; and wherein the convergent focal field has a focal field diameter selected from a group consisting of at least 6 mm, at least 8 mm and at least 10 mm; or wherein each location in the convergent focal field has a local center of curvature on a side facing away from the focusing optical unit; or wherein each location in the focal field has a focal field curvature selected from a group consisting of a radius RS ranging from 8 mm to 50 mm, from 10 mm to 30 mm and from 12 mm to 20 mm.
29. (canceled)
30. (canceled)
31. (canceled)
32. The planning unit as claimed in claim 26, wherein the focusing optical unit includes the second lens arrangement that provides perpendicular incidence of laser radiation on the curved surface; and wherein the curved surface has a diameter selected from a group consisting of at least 6 mm, at least 8 mm and at least 10 mm; or wherein the curved surface has a surface curvature with a radius R.sub.F selected from a group consisting of a range from 8 mm to 50 mm, a range from 10 mm to 30 mm and a range from12 mm to 20 mm; or wherein the planning unit has a working distance (A) in a range from 20 mm to 50 mm, or wherein the planning unit has an optical aperture selected from a group consisting of greater than 40 mm, greater than 50 mm, and greater than or equal to 60 mm; or wherein the planning unit comprises a first lens which has a first lens material with a first refractive index and a first Abbe number and comprising a second lens which has a second lens material with a second refractive index and a second Abbe number, with the first refractive index differing from the second refractive index and the first Abbe number differing from the second Abbe number; or wherein the focusing optical unit has at least two lens groups along a beam path with a non-imaging optical element being arranged therebetween; or a combination of the foregoing.
33. (canceled)
34. (canceled)
35. (canceled)
36. (canceled)
37. (canceled)
38. A UV laser-based system for vision correction (UVL-LVC system), comprising a focusing optical unit for a UV laser-based system for vision correction (UVL-LVC system) as claimed in claim 14; and a planning unit for generating planning data for a UV laser-based system for vision correction (UVL-LVC system) comprising: a control unit that controls the UVL-LVC system that is configured to take planning data into consideration; wherein the planning unit is configured to take account of geometry losses, Fresnel losses, a spatial extent of the laser radiation in the work surface or a combination of the foregoing when calculating the planning data; and wherein the planning unit has an interface operably coupled to the control unit, by which the planning data can be made available to the control unit.
39. The focusing optical unit as claimed in claim 14, wherein the focusing optical unit is configured to produce round laser spots having a full width at half maximum (FWHM) in a range from 0.3 to 0.8 mm in the focal field with a deviation chosen from a group consisting of less than 20% and less than 10%.
40. The focusing optical unit as claimed in claim 14, wherein the first lens arrangement which is configured to provide a convergent focal field is further configured to take into account a difference radius of curvature (R.sub.Δ) which represents an effective corneal curvature having effective corneal curvature values ranging from RA of 15 mm to R.sub.Δ of 450 mm for focal field radii of curvature of between 8 mm and 16 mm thereby facilitating an improved fluence loss function.
41. The focusing optical unit as claimed in claim 19, wherein the lens arrangement that provides perpendicular incidence of laser radiation on the curved surface is further configured such that the incidence of the laser radiation on the curved surface has an angle with a normal to the curved surface at a location of incidence that is selected from a group consisting of no more than 10 degrees, no more than five degrees and no more than 2 degrees.
42. The focusing optical unit as claimed in claim 19, wherein the lens arrangement that provides perpendicular incidence of laser radiation on the curved surface is further configured such that the incidence of the laser radiation on the curved surface occurs at a spot size in a range selected from a group consisting of between 0.3 mm to 1.5 mm and between 0.5 mm to 1.0 mm.
Description
BRIEF DESCRIPTION OF THE DRAWINGS
[0107] The invention is explained in greater detail below for example with reference to the accompanying drawings, which also disclose features essential to the invention. In the drawing:
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DETAILED DESCRIPTION
[0119]
[0120] An ablation profile 150 is not applied at the correct angle (i.e., with the center not on the surface normal, that is to say perpendicular to the visual axis 130) as a result of the “wrong” fixation of the patient's eye 110. This may occur if the patient preferably fixates in a largely fixed, but “wrong” direction, that is to say for example permanently gazes in a fixed direction that does not correspond to the center of the “fixation cloud” 120. This may occur should the patient, depending on refraction deficit and treatment duration, no longer be able to see the fixation target in focus during the operation. A prismatic correction error (tip/tilt) arises on account of the wrong fixation.
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[0122]
[0123]
[0124] Furthermore, the focal area 260 has a radius of curvature R.sub.S in the example shown. This radius of curvature has the same sign as the corneal curvature with the radius of curvature R.sub.C (“scanning radius of curvature”). Additionally, the two radii of curvature R.sub.C and R.sub.S have almost the same magnitude such that the focal area 260 extends close to the cornea 215.
[0125] The focusing optical unit shown in
[0126] In
[0127] The focusing optical unit shown here is particularly compact and has an installation size (length) of 54 mm in the case of an optical diameter of 56 mm, and provides a working distance of Δ=30 mm in the process.
[0128]
[0129] According to the sphere model, z(R,r)=r.sup.2/(R+√{square root over (R.sup.2−r.sup.2)}) applies. In this case, R describes the radius of a sphere, z describes the heights with respect to a tangent to this sphere, and r describes the distance along the tangent from the point of contact between circle and tangent.
[0130] The right-hand side of
Δz(R.sub.C, R.sub.S, r)=z(R.sub.C, r)−z(R.sub.S, r)=z(R.sub.Δ, r)
[0131] In this case, z.sub.C:=z(R.sub.C, r) and z.sub.S:=z(R.sub.S, r). This difference height Δz is intended to be determined by a difference radius of curvature R.sub.Δ. This corresponds to an “effective” corneal curvature for light incident from the z-direction, for example like for solutions according to the prior art (see also
[0132] Using the aforementioned formula for a sphere model, the following arises from the equation for the difference height Δz:
[0133] This relationship for determining R.sub.Δ applies to all r (in particular to r=0). This results in:
[0134] Consequently, the following arises for the “effective” corneal radius of curvature:
[0135] Consequently, with a typical corneal radius of curvature of R.sub.C=7.86 mm, values of approximately R.sub.Δ≈450 mm to approximately R.sub.Δ≈15 mm arise for the effective corneal curvature for focal field radii of curvature with values between approximately 8 mm and approximately 16 mm. In these regions the advantage of an improved fluence loss function is particularly clear since these effective radii are significantly larger than the typical radius of curvature of the cornea, and so an impingement of the cornea with laser light is significantly closer to perpendicular incidence than in the prior art.
[0136] Even though the observations shown here were made for a first variant of the focusing optical unit, they also apply to a focusing optical unit according to the second variant. In this case, the curved surface is identical to the focal field 460 (with R.sub.F=R.sub.S).
[0137]
[0138] In this case, γ is the angle between an incident laser ray for the focusing optical unit according to the invention with a convergent and curved focal field with respect to a focusing optical unit according to the prior art with telecentric focusing on a plane focal field. The following arises for the angle of incidence α.sub.SdT according to the prior art:
[0139] By contrast, the following applies to the focusing optical unit according to the invention:
α.sub.MB≈α.sub.SdT−γ
[0140] Then, the angle of reflection 2α.sub.MB+γ arises for the reflected laser ray 590 in the case of a lateral displacement Δ.sub.LS. In this case, Δ.sub.LS is used in the calculation for the pupil coordinate r.sub.SdT(≈r.sub.MB). In this case, the ophthalmic pole (OP) and the corneal vertex (CV) are equated to one another WLOG. In this example, a reflection angle of approximately 2α.sub.MB+γ=20° arises for an offset of Δ.sub.LS=2 mm. This angle is detected without problems by the focusing optical unit and can be processed in the UVL-LVC system.
[0141] The axis of symmetry 580 of the eye 510 is also depicted in
[0142] Even though the observations shown here were made for a first variant of the focusing optical unit, they also apply to a focusing optical unit according to the second variant. In this case, the curved surface is identical to the curved focal field (with R.sub.F=R.sub.S).
[0143] In the discussed configuration, the focusing optical unit (in both variants) is therefore particularly well suited to identify reflections such as the first Purkinje image and/or the vertex, and hence advantageously allows an improvement in the centration of the patient's eye with respect to the UVL-LVC system.
[0144]
[0145] In UVL-LVC systems, laser pulses are typically designed approximately as low-order supergaussians, from which the pulse ablation shape 620, 620* can then be calculated. By way of example, the latter can be implemented from a given pulse shape with the aid of the blow-off model. The geometry loss is modeled as a cosine function for an infinitesimal surface element dA 625, 625*. The following applies: cos(α)=dA/dA′, with the angle of incidence a (angle of incidence with respect to the local surface normal on the cornea 615) and the projected infinitesimal surface element dA′635, 635*. In comparison with solutions according to the prior art (to the left in
[0146]
[0147] The two upper graphs in
[0148] The two lower graphs in
[0149] Even though the observations shown here were made for a first variant of the focusing optical unit, they also apply to a focusing optical unit according to the second variant. In this case, the curved surface is identical to the curved focal field (with R.sub.F=R.sub.S).
[0150]
[0151] The calculations apply to the laser pulse maximum fluence (“peak fluence”). A spatial extent of the laser pulse (or of the laser radiation) was not taken into account for the calculation of the geometry and Fresnel losses. This is an approximation which improves as the pulse diameter decreases (ratio of pulse diameter to the diameter of the optical zone). Attention is drawn to the fact that taking account of the relationships shown below once again benefits the solution according to the invention. As representative values in all cases, 160 mJ/cm.sup.2 was taken for the “peak fluence” (F.sub.0) and 48 mJ/cm.sup.2 was taken for the stroma threshold ablation fluence (“threshold fluence”). The refractive index of the stroma was taken to be n=1.377.
[0152]
[0153] A spherical 5 D (dpt) correction in the case of a 4 mm pupil radius was considered as a case study. Attention is drawn to the fact that optical zones are usually located up to 6 mm, and often therebeyond, and, with transition zones of 1.5 mm, even lead to pupil radius coordinates closer to 4.5 mm (9 mm overall ablation diameter). Typically, hyperopic eyes (labeled as “more hyperopic like eyes”) exhibit on average larger corneal radii of curvature and require steepening, that is to say a reduction, of the corneal radii of curvature for correcting the visual defect (labeled by “hyperopia correction”). The opposite applies to myopic eyes (labeled “more myopic like eyes” and “myopia correction”).
[0154] The curves in the diagram of
[0155] The line labeled “FO.sub.SdT (with FLC.sub.SdT)” represents the deviation of the effective etch rate from the normalized target etch rate for a UVL-LVC system with a fluence loss compensation according to the prior art. This emerges from the calculated loss function and a typical compensation function according to the prior art, which does not consider the Fresnel losses but contains the cosine-dependent projection of the surface elements (cos(a) in
[0156] The line labeled “FO.sub.SdT (with FLC.sub.sdT+Fresnel)” represents the deviation for a system according to the prior art with a fluence loss compensation according to the prior art if the Fresnel losses are additionally considered. Essentially, it is possible to identify a shift of the function to the left, that is to say to smaller corneal radii of curvature (or “upward”, depending on the point of view). This is due to the fact that the Fresnel losses for unpolarized excimer laser pulses vary only slightly with the angle of incidence (cf. work point in
[0157] The line labeled “FO (with FLC)” represents the deviation of the effective etch rate from the normalized target etch rate for a UVL-LVC system with a focusing optical unit according to the invention (FO) and a compensation according to the invention (FLC). The latter considers the optical geometry (in this case, focal field curvatures R.sub.S of 12 mm and a working distance Δ of 40 mm) of the focusing optical unit according to the invention for the compensation function. The curve once again arises from the calculated loss function and the compensation function according to the invention. The latter also considers the Fresnel losses in addition to the geometry losses (which are low in comparison with FO.sub.SdT) and uses the preoperative corneal radius of curvature for the compensation. The variation of this function over the corneal radii of curvature is significantly reduced in relation to a focusing optical unit according to the prior art. This leads to a significantly improved predictability or to a reduction in the variation of the refractive result, as will still be explained below.
[0158] The line labeled “FO (with FLC.sub.SdT)” represents the deviation of the effective etch rate from the normalized target etch rate for a UVL-LVC system with a focusing optical unit according to the invention (FO), which arises if use were to be made of the above-described compensation function according to the prior art (FLC.sub.SdT). Even in this case, the deviations of the effective etch rates for the arrangement according to the invention would still be approximately one order of magnitude smaller than in the case of the prior art. This is substantially based on the above-described “more good-natured” curve of the geometry losses over the pupil coordinates (see
[0159] Finally, the line labeled “FO.sub.SdT (with FLC)” represents the deviation of the effective etch rate from the normalized target etch rate for a UVL-LVC system with a focusing optical unit according to the prior art (FO.sub.SdT) if the compensation function according to the invention FLC were to be applied. The profile of the curve shows that the compensation function according to the invention FLC already leads to significant improvement in the predictability of the refractive result.
[0160] Even though the observations shown here were made for a first variant of the focusing optical unit, they also apply to a focusing optical unit according to the second variant. In this case, the curved surface is identical to the curved focal field (with R.sub.F=R.sub.S).
[0161] The intention is now to explain why the concept according to the invention is particularly advantageous in relation to an improved predictability of the refractive results.
[0162] The curve of the percentage deviations of the etch rates for a UVL-LVC system with a focusing optical unit according to the prior art, shown in
[0163] For prior art systems, the keratometry can now be taken into account in the nomogram as follows: Let the mean value of the keratometry in the considered hyperopia group for the nomogram correction be R.sub.C=8.25 mm. If a hyperopic patient with a keratometry deviating therefrom and assumed to be R.sub.C=7.25 mm is now treated, it is possible to read the difference in the ablation rate that would not be corrected from the diagram in
[0164] The non-optimal energy compensation, which quite fundamentally is due to the ablation geometry of
[0165] One could object that it is possible to apply an exact energy correction to UVL-LVC systems according to the prior art. This is fundamentally true but not implementable in practice. Ideally, the current corneal shape at the pupil position during the ablation would be determined for the next laser pulse. However, this cannot be done with current technology (processing speed, control speed), and would be accompanied by other limitations and problems. Alternatively, attempts could be made to take account of the current corneal shape during the pulse sorting process. This would represent a great advance and is categorically doable from the view of the sorting algorithms (sorting of the pulses for etch optimization). However, a subsequent and necessary thermal sort would then be impossible without undoing the previously considered improvement (resorting of the pulses). There is currently no prospect of a physical and mathematical method for combining sort and thermal sort (“simultaneously”). Therefore, the minimizing of the energy correction by the optical unit according to the invention and the consideration of the K-values offers an improvement of the predictability of the results, a reduction in the variation and, moreover, also an improvement of the nomograms as these have to correct smaller deviations per se.
[0166] A feature of the planning unit according to the invention is that the remaining aberrations and hence the spot variations in the focal field are measured or physically modeled for the calculation of the planning data and are made available to the sorting algorithm. These data can be used to determine the accurate ablation-effective fluence distribution of the pulses in the focal field as a function of the focal field position, and hence to take this into account when sorting the pulses (see
[0167]
[0168] Furthermore, the UVL-LVC system comprises what is known as an “alignment beam laser” 780. The latter serves to adjust the optical system and/or carry out an alignment with respect to the eye. The laser beam of the alignment beam laser follows the laser beams 770 of the excimer laser 720 on the cornea 715 and its focus. The “alignment beam laser” 780 is situated in the base unit of the UVL-LVC system 705.
[0169] Attention should be drawn to the fact that one or more deflectors 740 may also be embodied as beam splitters. This allows integration of other components, for example detectors for the detection of the collected corneal reflections or an observation camera. Various arrangements immediately evident to an expert but not plotted in
[0170]
[0171] In contrast to the exemplary embodiment shown in
[0172]
[0173] The aforementioned features of the invention, which are explained in various exemplary embodiments, can be used not only in the combinations specified in an exemplary manner but also in other combinations or on their own, without departing from the scope of the present invention.