Fertilized egg or sperm injector
09848969 · 2017-12-26
Assignee
- National Federation Of Agricultural Cooperative Associations (Tokyo, JP)
- YAMANETECH, INC. (Ina-Shi, JP)
- AIR WATER MACH INC. (Matsumoto-Shi, JP)
Inventors
- Seiichi Yamane (Ina, JP)
- Masako Tugane (Hokuto, JP)
- Yutaka Takebuchi (Matsumoto, JP)
- Koji Ohmori (Matsumoto, JP)
Cpc classification
A61D19/027
HUMAN NECESSITIES
International classification
Abstract
An injector for injecting a fertilized ovum(ova) or a sperm(s) for artificial insemination into a uterine body, by which an injection pipe can be introduced smoothly into a uterus, is disclosed. An injector for a fertilized ovum(ova) or a sperm(s) of the invention is characterized in that it comprises a guide pipe for insertion into a uterine body, an injection pipe which is inserted into the guide pipe and has a length longer than the guide pipe, and a nozzle connected to a frontal end of the injection pipe, wherein the injection pipe comprises a flexible 1st pipe section constituting a frontal side of the injection pipe, and a 2nd pipe section being more rigid than the 1st pipe section and constituting a rear side of the injection pipe.
Claims
1. An injector for injecting a fertilized ovum(ova) or a sperm(s) for artificial insemination into a uterine body, comprising: a guide pipe for insertion into a uterine body, an injection pipe, which is inserted into the guide pipe, and has a length longer than the guide pipe, and a nozzle connected to a frontal end of the injection pipe, wherein the injection pipe comprises a flexible first pipe section constituting a frontal side of the injection pipe, and a second pipe section being more rigid than the first pipe section and constituting a rear side of the injection pipe, wherein a cylindrical connector is connected with a rear end of the second pipe section, wherein the injection pipe comprises: a flexible tube having a length longer than the guide pipe, and being inserted into the guide pipe; and a rigid sleeve which is arranged so that an outside of a rear part of the tube is covered with the rigid sleeve, leaving a frontal part of the tube in an exposed state, and whose rigidity is higher than the tube, wherein the first pipe section is constituted by a portion of the tube protruding from the rigid sleeve at a frontal side, and the second pipe section is constituted by the rigid sleeve and a portion of the tube positioned inside the rigid sleeve, wherein the nozzle comprises a stopping part having an outer diameter size larger than an inner diameter size of the guide pipe, and a connecting cylindrical part connected to the frontal end of the injection pipe on a rear side from the stopping part, wherein the connecting cylindrical part is inserted into the injection pipe at a connection part between the injection pipe and the connecting cylindrical part, and wherein at least either one of a protruding part(s) that bite(s) into an inner surface of the injection pipe and a recessed part(s) that is(are) bitten into by the injection pipe is formed on an outer surface of the connecting cylindrical part.
2. The injector according to claim 1, wherein the cylindrical connector is an integrally molded item which is made of a resin or a rubber and comprises a plurality of step parts formed on an inner circumferential surface thereof, said step parts each enlarging an inner diameter size at both sides of a central portion in an axis line direction.
3. The injector according to claim 1, wherein an outer peripheral surface of the cylindrical connector has a shape for preventing rotation of the cylindrical connector around an axis line.
4. The injector according to claim 1, wherein at least a frontal end of the rigid sleeve is fixed to the tube by adhesion.
5. The injector according to claim 1, wherein the stopping part is formed by a portion of the nozzle, the outer diameter size of which increases continuously from a rear side toward a frontal side, and a portion ranging from a connection part between the injection pipe and the connecting cylindrical part to the stopping part extends without any step part having an outer diameter size larger than the outer diameter size of the first pipe section and facing toward the injection pipe.
6. The injector according to claim 1, comprising a click mechanism for changing a load when the injection pipe is advanced or retreated in the guide pipe, said click mechanism being provided between the injection pipe and the guide pipe.
7. The injector according to claim 1, wherein a frontal end of the rigid sleeve is not exposed outside of the guide pipe in a state where a frontal side of the injection pipe is pushed out from the guide pipe.
8. The injector according to claim 1, wherein the injection pipe does not have a reinforcing layer with which a boundary part between the first pipe section and the second pipe section is covered.
9. The injector according to claim 1, wherein the protruding part does not have a spiral shape.
Description
BRIEF DESCRIPTION OF THE DRAWINGS
(1)
(2)
(3)
(4)
(5)
(6)
(7)
(8)
(9)
(10)
(11)
(12)
(13)
MODE FOR CARRYING OUT THE INVENTION
(14) Preferred embodiments of the present invention will be specifically described below by way of drawings.
(15) [Embodiment 1]
(16) (Overall Construction)
(17)
(18) As shown in
(19) For injecting, for example, a fertilized ovum into the uterine body of a cow using the injector 1 constructed as above, the guide pipe 2 is inserted through the vaginal opening into the uterine body A1 in a state where the injection pipe 3 is pulled in the guide pipe 2 as shown in
(20) Next, as shown in
(21) In such an injection operation, the guide pipe 2 may be inserted into the uterine body A1 in a state where at least a part of the injector 1 to be inserted into the uterine body A1 is covered with a thin cover made of a plastic film or the like (not illustrated), and thereafter the frontal end of the injector 1 may be protruded out of the cover, and then the injection pipe 3 may be pushed out from the front tip of the guide pipe 2 to bring the nozzle 4 to a deep part of the uterine horn A11.
(22) (Detailed Construction of Injector 1)
(23)
(24) As shown in
(25) In the present Embodiment, the outside of a portion of the tube 30 located apart from the nozzle 4 toward the rear side is covered with a reinforcing sleeve 35. In the present Embodiment, as the reinforcing sleeve 35, a flexible sleeve 36 which covers the outside of a portion of the tube 30 located apart from the nozzle 4 toward the rear side and a rigid sleeve 37 which covers the outside of the tube 30 on the rear side from the flexible sleeve 36 are used. The flexible sleeve 36 and the rigid sleeve 37 are placed such that they partially overlap.
(26) The length of the tube 30 is larger than the length of the rigid sleeve 37 and the length of the guide pipe 2, and the rear edge of the tube 30 is located at the same position as the rear edge of the rigid sleeve 37. Consequently, in the injection pipe 3, a frontal side of the tube 30 protrudes from the frontal end of the rigid sleeve 37, and a base part of the portion of the tube 30 protruding from the rigid sleeve 37 is covered with the flexible sleeve 36. As a result, the injection pipe 3 has a structure in which the rigidity increases in a stepwise fashion from the frontal side to the rear side.
(27) In the present Embodiment, at an overlapping part 350 of the flexible sleeve 36 and the rigid sleeve 37, the tube 30 is covered with the sleeves such that the flexible sleeve 36 is placed outside the rigid sleeve 37. The rigid sleeve 37 is a rigid pipe made of a metal or a hard resin, and the flexible sleeve 36 is made of a heat-shrinkable resin such as a polyester resin or a poly(vinyl chloride) resin. Consequently, the rigid sleeve 37 has a rigidity higher than the flexible sleeve 36 and the tube 30. The flexible sleeve 36 is placed around the tube 30 by heat-shrinking of a sleeve made of a heat-shrinkable resin. More specifically, the tube 30 is inserted in the rigid sleeve 37 and then inserted in the flexible sleeve 36, and thereafter, the flexible sleeve 36 is heat-shrunk, so that the tube 30 becomes covered with the flexible sleeve 36. Even in such a constitution, the outer diameter size of the injection pipe 3 can be less than the inner diameter size of the guide pipe 2 at any point in a longitudinal direction. Thus, the injection pipe 3 is movable inside the guide pipe 2 in a longitudinal direction. For inserting the tube 30 into the rigid sleeve 37, the tube 30 may be pulled in a longitudinal direction to make its diameter smaller, and in this state the tube 30 may be inserted into the rigid sleeve 37, followed by releasing the tube 30 from the tension.
(28) The injection pipe 3 is connected with a cylindrical connector 6 at the rear part of the rigid sleeve 37. The length of the tube 30 is larger than the length of the guide pipe 2, and the length of the rigid sleeve 37 is slightly larger than the length of the guide pipe 2. Accordingly, when the rear side of the injection pipe 3 (rigid sleeve 37) is manipulated to push forward the rear end of the injection pipe 3 (cylindrical connector 6) such that the rear end of the injection pipe 3 (cylindrical connector 6) contacts the flange 21 of the guide pipe 2, a portion of the tube 30 protruding from the rigid sleeve 37 comes into a state where the portion protruding from the rigid sleeve 37 protrudes from the frontal end of the guide pipe 2.
(29) In contrast to the above, when the injection pipe 3 is pulled toward the rear side by manipulating the rear side of the injection pipe 3 (cylindrical connector 6), the injection pipe 3 is drawn into the guide pipe 2 until a stopping part 45 of the nozzle 4 described below contacts the frontal end of the guide pipe 2 as shown in
(30) As described above, in the injector 1 of the present Embodiment, the injection pipe 3 comprises a flexible 1st pipe section 3a which constitutes the frontal side of the injection pipe 3, and a 2nd pipe section 3b which has a rigidity higher than the 1st pipe section 3a and constitutes the rear side of the injection pipe 3. More specifically, the injection pipe 3 comprises a flexible tube 30 which is longer than the guide pipe 2 and is inserted in the guide pipe 2, and a rigid sleeve 37 which is arranged so that the outside of a rear part of the tube 30 is covered with the sleeve 37, leaving a frontal part of the tube 30 in an exposed state. Therefore, in the present Embodiment, the 1st pipe section 3a is constituted by a portion of the tube 30 protruding from the rigid sleeve 37 on a frontal side, and the 2nd pipe section 3b is constituted by the rigid sleeve 37 and a portion of the tube 30 positioned inside the rigid sleeve 37. The length of the 1st pipe section 3a may be approximately from 12 cm to 18 cm.
(31) Both edges of the rigid sleeve 37 are bonded to the tube 30 with an adhesive. More specifically, the frontal end of the rigid sleeve 37 is bonded to the outer peripheral surface of the tube 30 by an adhesive, and the rear end surface of the rigid sleeve 37 and the rear end surface of the tube 30 are bonded together by an adhesive. Therefore, the rigid sleeve 37 and a portion of the tube 30 positioned inside the rigid sleeve 37 are united. As a consequence, when the rear side of the injection pipe 3 (rigid sleeve 37) is manipulated, the tube 30 moves with the rigid sleeve 37 in an integrated manner. The tube 30 and the rigid sleeve 37 may be bonded together through the entire length inside the rigid sleeve 37.
(32) Further, the injection pipe 3 has a reinforcing layer 33 composed of the flexible sleeve 36 which covers a boundary part between the 1st pipe section 3a and the 2nd pipe section 3b. As a result, the injection pipe 3 has a structure in which the rigidity increases in a stepwise fashion from the frontal side to the rear side.
(33) (External Shape of Nozzle 4)
(34) As shown in
(35) In the above-described nozzle 4, the outer diameter size D45 of the stopping part 45 is larger than the inner diameter size D2 of the guide pipe 2, as shown by the following formula:
D2<D45
(36) D45=Outer diameter size of stopping part 45
(37) D2=Inner diameter size of guide pipe 2
(38) Therefore, the stopping part 45 of the nozzle 4 functions as a stopper, which contacts the frontal end of the guide pipe 2, when the injection pipe 3 is pulled toward the rear side.
(39) A connection part 40 between the nozzle 4 and the injection pipe 3 is constituted such that the frontal end of the injection pipe 3 is inserted into the connecting cylindrical part 41, and the connecting cylindrical part 41 covers the outside of the frontal end of the injection pipe 3. An outer peripheral surface of the connecting cylindrical part 41 is formed into a tapered surface 44 whose diameter decreases continuously toward the rear side. As a result, the outer diameter size D41 of the rear edge 410 of the connecting cylindrical part 41 is reduced to the outer diameter size of the injection pipe 3 (outer diameter size D30 of tube 30) or less as expressed by the following formula:
D41≦D30
(40) D41=Outer diameter size of rear edge 410 of connecting cylindrical part 41
(41) D30=Outer diameter size of tube 30
(42) Therefore, no step part which has an outer diameter size larger than the outer diameter size D30 of the injection pipe 3 and faces toward the injection pipe 3 is formed in the connection part 40. In such an Embodiment, when the frontal end of the injection pipe 3 is inserted into the connecting cylindrical part 41, a bulge 30s occurs at a part of the tube 30 adjacent to the rear edge 410 of the connecting cylindrical part 41 as shown in
(43) In the nozzle 4 of the present Embodiment, a trunk 46 extending with a constant outer diameter size D46 is formed between the tapered surface 44 and the stopping part 45, and the outer diameter size D46 of the trunk 46 is larger than the outer diameter size D41 of the rear edge 410 of the connecting cylindrical part 41 and the outer diameter size D30 of the injection pipe 3, and smaller than the inner diameter size D2 of the guide pipe 2 and the outer diameter size D45 of the stopping part 45, as expressed by the following formula:
D41≦D30<D46<D2<D45
(44) The stopping part 45 is formed by a portion of the nozzle 4, the outer diameter size of which increases continuously from a rear side toward a frontal side, and in the vicinity of the stopping part 45, any step part which has an outer diameter size larger than the outer diameter size D30 of the injection pipe 3 and faces toward the injection pipe 3 is not formed. That means, a portion between the stopping part 45 and the trunk 46 has a slope shape such as a tapered surface which increases the diameter from the side of the trunk 46 toward the stopping part 45, and comprises no step having an edge surface at a right angle to the axis direction. Further, between the trunk 46 and the tapered surface 44, a step part having an outer diameter size larger than the outer diameter size D30 of the injection pipe 3 and facing toward the injection pipe 3 is not formed. Therefore, a portion ranging from the connection part 40 between the injection pipe 3 and the connecting cylindrical part 41 to the stopping part 45 extends without any step part having an outer diameter size larger than the outer diameter size D30 of the injection pipe 3 and facing toward the injection pipe 3.
(45) (Connection Structure between Nozzle 4 and Injection Pipe 3)
(46) In the present Embodiment, for connecting the nozzle 4 with the injection pipe 3, a connection part 40 with a structure in which the frontal end of the injection pipe 3 is inserted in the connecting cylindrical part 41 is constituted, and a hollow part 47 communicating with the nozzle holes 48 is formed inside the connecting cylindrical part 41. A reinforcing pipe for connection 5 as thin as an injection needle is inserted into the tube 30 at the frontal part of the tube 30, and when the frontal side of the tube 30 is inserted into the connecting cylindrical part 41 (hollow part 47), the frontal end of the tube 30 is inserted in the annular space 49 between the connecting cylindrical part 41 and the reinforcing pipe for connection 5 in an elastically deformed state. The frontal part of the tube 30 may have a shape extending with a constant outer diameter size, or, in order to facilitate insertion into the connecting cylindrical part 41, a tapered surface may be formed in advance on the entire circumference of the frontal part of the tube 30 such that the diameter of the tube 30 decreases toward the frontal tip.
(47) In the hollow part 47 of the nozzle 4, a large diameter part 471 into which the frontal end of the tube 30 is inserted and a small diameter part 472 which communicates with the nozzle holes 48 are formed, and a reinforcing pipe holding part 473 having a middle inner diameter size that is approximately the same as the outer diameter size of the reinforcing pipe for connection 5 is formed between the large diameter part 471 and the small diameter part 472. More specifically, the reinforcing pipe for connection 5 protrudes partially from the frontal end of the tube 30, and when the frontal side of the tube 30 is inserted in the connecting cylindrical part 41 (hollow part 47) in a state where the reinforcing pipe for connection 5 is inserted into the frontal end of the tube 30, the frontal end of the reinforcing pipe for connection 5 is inserted and retained in the reinforcing pipe holding part 473.
(48) In connecting the nozzle 4 with the injection pipe 3, when the frontal end of the tube 30 is inserted into the connecting cylindrical part 41, a method utilizing mutual fitting between the components without using an adhesive may be employed, or, when the frontal end of the tube 30 is inserted into the connecting cylindrical part 41, a method in which an adhesive is applied beforehand to the outer peripheral surface of the frontal part of the tube 30, the outer peripheral surface of the reinforcing pipe for connection 5, and the inner circumferential surface of the large diameter part 471, etc., may be employed. Further, when inserting the reinforcing pipe for connection 5 into the tube 30, a method utilizing mutual fitting between the components without using an adhesive may be employed, or, when the reinforcing pipe for connection 5 is inserted into the frontal end of the tube 30, a method in which an adhesive is applied beforehand to the inner circumferential surface of the frontal part of the tube 30 and the outer peripheral surface of the reinforcing pipe for connection 5 may be employed. Since the reinforcing pipe for connection 5 is inserted into the frontal end of the tube 30, even in cases where an adhesive is applied to the outer peripheral surface of the frontal end of the tube 30, the outer peripheral surface of the reinforcing pipe for connection 5, the inner circumferential surface of the large diameter part 471, and the inner circumferential surface of the frontal part of the tube 30, the adhesive is not exposed to a flow channel of the injection pipe 3. Consequently, decrease in the conception rate to be caused by a contact between an adhesive and a fertilized ovum(ova) or a sperm(s) does not occur.
(49) (Constitution of Cylindrical Connector 6)
(50)
(51) As shown in
(52) Inside the cylindrical connector 6, a small diameter part 65 is arranged between the large diameter part 61 connected to the connecting port 610 and the middle diameter part 62 connected to the connecting port 620, and the small diameter part 65 has a smaller diameter than the middle diameter part 62. The cylindrical connector 6 having such a constitution is used for connecting the injection pipe 3 and the fluid supplier 8 when a fertilized ovum(ova) or a sperm(s) for artificial insemination charged inside the injection pipe 3 is supplied to the nozzle 4. Further, the cylindrical connector 6 may also be used for charging a fertilized ovum(ova) or a sperm(s) for artificial insemination inside the injection pipe 3. Furthermore, in some cases, a straw 7 in which a fertilized ovum(ova) or a sperm(s) for artificial insemination is(are) retained may be loaded inside the the cylindrical connector 6 itself. In such cases, the straw 7 is held by the fluid supplier 8 and the injection pipe 3 from both sides in a state of being placed in the small diameter part 65. Therefore, when a fluid is supplied from the fluid supplier 8, a fertilized ovum(ova) retained in the straw 7 together with an embryo medium is(are) transferred to the injection pipe 3, and supplied to the nozzle 4 through the injection pipe 3. In some other cases, the straw 7 may be connected between the cylindrical connector 6 and the injection pipe 3, or between the cylindrical connector 6 and the fluid supplier 8, and in this state a fluid may be supplied from the fluid supplier 8.
(53) In the present Embodiment, the small diameter part 65 is composed of a 1st small diameter part 63 positioned on the side of the connecting port 620 and a 2nd small diameter part 64 which has an inner diameter smaller than the 1st small diameter part 63 and is positioned between the 1st small diameter part 63 and the large diameter part 61. Therefore, a plurality of small step parts 661, 662, 663 are formed on an inner circumferential surface of the cylindrical connector 6, by which the inner diameter size is enlarged at both sides of the central portion (2nd small diameter part 64) in an axis line direction, and no large step part is formed. Furthermore, the cylindrical connector 6 is made of a thermosetting rubber such as a silicone rubber, and has suitable flexibility (elasticity) and rigidity immediately after molding. Therefore, the cylindrical connector 6 can be produced by a so-called forced demolding method, in which a stepped rod-like part S, a mold for forming a hollow part of a cylindrical connector 6, is pulled out through the connecting port 610 as shown by the arrow S1 in
(54) The outer peripheral surface of the cylindrical connector 6 may have a shape for preventing rotation of the cylindrical connector 6. More specifically, although the cylindrical connector 6 is as a whole cylindrical as shown in
(55) (Main Effects of the Present Embodiment)
(56) As described above, in using the injector 1 according to the present Embodiment, the guide pipe 2 is inserted through a vaginal opening into a uterine body in a state where the injection pipe 3 is pulled in the guide pipe 2, and then the injection pipe 3 is pushed out from the front tip of the guide pipe 2 so as to bring the nozzle 4 to a deep part of the uterine body. Then a fertilized ovum(ova) or a sperm(s) is(are) supplied through the injection pipe 3 to the nozzle 4 by means of a fluid supplied from the fluid supplier 8 and discharged from the nozzle 4. Thereafter the injector 1 is pulled out carefully from the vaginal opening.
(57) A portion of the injection pipe 3 which protrudes from the front tip of the guide pipe 2 when the injection pipe 3 is pushed out toward the frontal side is a flexible 1st pipe section 3a composed of the tube 30, and therefore the nozzle 4 arranged at the frontal side of the 1st pipe section 3a can reach a deep part of the uterine horn A11. During the action, a uterus inner wall is not wounded because the 1st pipe section 3a is flexible. Moreover, since a rear part of the injection pipe 3 protruding from the rear part of the guide pipe 2 is a 2nd pipe section 3b, which is more rigid than the 1st pipe section 3a, buckling of the 2nd pipe section 3b does not take place when the 2nd pipe section 3b is manipulated to push out the injection pipe 3 from the front tip of the guide pipe 2. Thus, the frontal side of the injection pipe 3 can be pushed out smoothly from the guide pipe 2 into the uterus, and therefore the operability in injecting a fertilized ovum(ova) or a sperm(s) is superior. Hence, an injection operation of a fertilized ovum(ova) or a sperm(s) can be performed efficiently according to the present Embodiment.
(58) The injection pipe 3 comprises a flexible tube 30 which is longer than the guide pipe 2 and is inserted in the guide pipe 2, and a rigid sleeve 37 which is arranged so that the outside of a rear part of the tube 30 is covered with the sleeve 37, leaving a frontal part of the tube 30 in an exposed state. Therefore, in the present Embodiment, the 1st pipe section 3a is constituted by a portion of the tube 30 protruding from the rigid sleeve 37 on a frontal side, and the 2nd pipe section 3b is constituted by the rigid sleeve 37 and a portion of the tube 30 positioned inside the rigid sleeve 37. Therefore, by using a clean tube as the tube 30, contamination of a fertilized ovum(ova) or a sperm(s) can be prevented. Further, since a flexible tube 30 functions as a heat insulating material, impairment of the activity of a fertilized ovum(ova) or a sperm(s) due to overcooling will not occur even when an injection operation is carried out in a low temperature atmosphere, e.g., in wintertime.
(59) Since at least the frontal end of the rigid sleeve 37 is bonded to the outer peripheral surface of the tube 30 by an adhesive, a portion of the tube 30 positioned inside the rigid sleeve 37 moves with the rigid sleeve 37 in an integrated manner when the rigid sleeve 37 is manipulated. Further, an injection pipe 3 is flexible only at the 1st pipe section 3a. Therefore, when the rear side of the 2nd pipe section 3b (rigid sleeve 37) of the injection pipe 3 is manipulated to be pushed forward, the nozzle 4 accurately follows the manipulation and moves toward a deep part of the uterus. Consequently, the injector 1 of the present Embodiment is superior in operability.
(60) A cylindrical connector 6 is connected to the rear part of the 2nd pipe section 3b. Therefore, the fluid supplier 8 for supplying a fluid for transporting a fertilized ovum(ova) or a sperm(s) to the nozzle 4 can be connected to the rear side of the injection pipe 3 via the cylindrical connector 6, and thus the fluid supplier 8 can be easily connected to the injection pipe 3. Further, since the cylindrical connector 6 is connected to the 2nd pipe section 3b having a high rigidity, a situation where the fluid supplier 8 hangs down will not occur. Therefore, the injector of the present Embodiment has the advantage that the fluid supplier 8 is easy to handle.
(61) Further, since the nozzle 4 comprises a stopping part 45 having an outer diameter size larger than the inner diameter size of the guide pipe 2, the nozzle 4 is not pulled into the guide pipe 2 when the injection pipe 3 is pulled into the guide pipe 2.
(62) The stopping part 45 is formed such that the outer diameter size increases continuously from a rear side toward a frontal side. At the connection part 40 between the injection pipe 3 and the nozzle 4, the frontal end of the injection pipe 3 is inserted into the connecting cylindrical part 41. On the outer peripheral surface of the connecting cylindrical part 41, a tapered surface 44 is formed, which reduces the diameter continuously toward the rear side so that the outer diameter size of the rear edge of the connecting cylindrical part 41 is reduced to the outer diameter size of the injection pipe 3 or less. Therefore, a portion ranging from the connection part 40 between the injection pipe 3 and the connecting cylindrical part 41 of the nozzle 4 to the stopping part 45 does not comprise any step part having an outer diameter size larger than the outer diameter size of the injection pipe 3. Therefore, when the injector 1 is pulled out from the vaginal opening after injection of a fertilized ovum(ova), such a situation where the uterus inner wall is wounded by a step will not occur. Further, such a situation where the fertilized ovum(ova) is(are) caught and scraped out by a step will not occur. Therefore, the conception rate can be improved. Further, since there is no step, the stopping part 45 gradually comes to a plugged state in the guide pipe 2 when the injection pipe 3 is pulled into the guide pipe 2. Consequently, such a situation where a strong force is suddenly given to the nozzle 4 is not occur, and thus the connection strength between the nozzle 4 and the injection pipe 3 is not compromised. Therefore, the nozzle 4 can be prevented from falling off from the injection pipe 3 and remaining in a uterine body.
(63) At the frontal end of the injection pipe 3, the reinforcing pipe for connection 5 is inserted into the injection pipe 3, and the frontal end of the injection pipe 3 is fitted into the annular space 49 between the reinforcing pipe for connection 5 and the connecting cylindrical part 41. As a consequence, even when the injection pipe 3 is pushed into the connecting cylindrical part 41 of the nozzle 4, a situation where the injection pipe 3 is squashed will not occur, and therefore a flow channel can be secured. In addition, since the injection pipe 3 is fitted in the annular space 49 between the connecting cylindrical part 41 of the nozzle 4 and the reinforcing pipe for connection 5, the connection strength between the nozzle 4 and the injection pipe 3 is high. Therefore, the nozzle 4 can be securely prevented from falling off from the injection pipe 3.
(64) Further, a reinforcing pipe holding part 473 which holds the frontal end of the reinforcing pipe for connection 5 is arranged inside the the nozzle 4. Since the injection pipe 3 is fitted in the annular space 49 between the connecting cylindrical part 41 of the nozzle 4 and the reinforcing pipe for connection 5 held by the nozzle 4, the connection strength between the nozzle 4 and the injection pipe 3 is high. Therefore, the nozzle 4 can be securely prevented from falling off from the injection pipe 3.
(65) The injection pipe 3 comprises a flexible tube 30 and a reinforcing sleeve 35 covering the outside of a portion of the tube 30 located apart from the nozzle 4 toward the rear side. Further, as a reinforcing sleeve 35, a flexible sleeve 36 and a rigid sleeve 37 placed on the rear side of the flexible sleeve 36 cover the tube 30. Therefore, the injection pipe 3 is covered with the reinforcing layer 33 composed of the flexible sleeve 36 at a boundary part between the 1st pipe section 3a and the 2nd pipe section 3b to form a constitution in which the rigidity of the injection pipe 3 increases from the frontal side to the rear side. Therefore, buckling is unlikely to occur at the frontal side of the injection pipe 3 when the injection pipe 3 is pushed out from the guide pipe 2, and thus the frontal end of the injection pipe 3 (nozzle 4) can be easily advanced to a deep part of a uterine body.
(66) [Embodiment 2]
(67)
(68) Although in Embodiment 1 a reinforcing pipe for connection 5 is used for connecting the injection pipe 3 (tube 30) and the nozzle 4, in the present Embodiment as shown in
(69) [Embodiment 3]
(70)
(71) As shown in
(72) In the nozzle 4 having such a structure, the outer diameter size D45 of the stopping part 45 is larger than the inner diameter size D2 of the guide pipe 2, and the stopping part 45 of the nozzle 4 functions as a stopper which contacts the frontal end of the guide pipe 2 when the injection pipe 3 is pulled toward the rear side.
(73) According to the present Embodiment, a connection part 40 between the nozzle 4 and the injection pipe 3 is constituted such that a connecting cylindrical part 42 is inserted into the injection pipe 3, and the injection pipe 3 covers the outside of the connecting cylindrical part 42. Hence, in the connection part 40, no step part which has an outer diameter size larger than the outer diameter size of the injection pipe 3 and faces toward the injection pipe 3 is formed. The connecting cylindrical part 42 has a shape in which a single protruding part 420 or a plurality of protruding parts 420 are formed on the outer peripheral surface of a cylindrical part having an outer diameter size approximately the same as the inner diameter size of the injection pipe 3 (inner diameter size D31 of tube 30). Consequently, when the connecting cylindrical part 42 is inserted into the injection pipe 3, the protruding parts 420 come to bite into the injection pipe 3 (tube 30). As a consequence of formation of the protruding parts 420, recessed parts 422 that are to be bitten into by the injection pipe 3 (tube 30) are formed on the outer peripheral surface of the connecting cylindrical part 42. According to the present Embodiment, the protruding parts 420 have a cross-sectional shape of approximately right-angled triangle with the hypotenuse facing the rear side where the injection pipe 3 extends. Therefore, in the case where the protruding parts 420 are formed on the outer peripheral surface of the connecting cylindrical part 42, the connecting cylindrical part 42 can be easily inserted into the injection pipe 3. In addition, since the protruding parts 420 wedge into the flexible tube 30, a strong resistance force is exhibited against a force for pulling the connecting cylindrical part 42 out of the injection pipe 3. Although in
(74) The stopping part 45 is formed by a portion of the nozzle 4 whose outer diameter size increases continuously from the rear side toward the frontal side, and any step part which has an outer diameter size larger than the outer diameter size D30 of the injection pipe 3 and faces toward the injection pipe 3 is not formed in the vicinity of the stopping part 45. That means, a portion between the stopping part 45 and the trunk 46 has a slope shape such as a tapered surface which increases the diameter from the side of the trunk 46 toward the stopping part 45, and comprises no step having an edge surface at a right angle to the axis direction. Although the outer diameter size D46 of the trunk 46 is larger than the outer diameter size D30 of the injection pipe 3, the outer diameter size of a portion of the injection pipe 3 which covers the connecting cylindrical part 42 is the same as the outer diameter size D46 of the trunk 46, or slightly larger than the outer diameter size D46 of the trunk 46. Hence, a boundary part between the trunk 46 and the injection pipe 3 also comprises no step part which has an outer diameter size larger than the outer diameter size of the injection pipe 3 and faces toward the injection pipe 3. Therefore, a portion ranging from the connection part 40 between the injection pipe 3 and the connecting cylindrical part 41 to the stopping part 45 does not comprise any step part which has an outer diameter size larger than the outer diameter size D30 of the injection pipe 3 and faces toward the injection pipe 3.
(75) In connecting the nozzle 4 with the injection pipe 3, when the frontal part of the tube 30 is placed around the connecting cylindrical part 42, a method utilizing mutual fitting between the components without using an adhesive may be employed, or, when the frontal part of the tube 30 is placed around the connecting cylindrical part 42, a method in which an adhesive is applied beforehand to the inner circumferential surface of the frontal part of the tube 30 and/or the outer peripheral surface of the connecting cylindrical part 42, etc., may be employed. In this case, since the frontal part of the tube 30 covers the outside of the connecting cylindrical part 42, the adhesive is not exposed to a flow channel of the injection pipe 3 even when an adhesive is applied to the inner circumferential surface of the frontal part of the tube 30 or the outer peripheral surface of the connecting cylindrical part 42. Therefore, decrease in the conception rate due to a contact between an adhesive and a fertilized ovum(ova) or a sperm(s) does not take place.
(76) As described above, in the injector 1 of the present Embodiment, similarly to Embodiment 1, the stopping part 45 is formed such that the outer diameter size increases continuously from a rear side toward a frontal side. At the connection part 40 between the injection pipe 3 and the nozzle 4, the frontal part of the injection pipe 3 is placed around the connecting cylindrical part 42. Therefore, a portion ranging from the connection part 40 between the injection pipe 3 and the connecting cylindrical part 42 of the nozzle 4 to the stopping part 45 extends without any step part having an outer diameter size larger than the outer diameter size of the injection pipe 3 and facing toward the injection pipe 3. Therefore, when the injector 1 is pulled out from the vaginal opening after injection of a fertilized ovum(ova), such a situation where the uterus inner wall is wounded by a step will not occur. Further, such a situation where the fertilized ovum(ova) is(are) caught and scraped out by a step will not occur. Therefore, the conception rate can be improved. Furthermore, since the outer diameter size of the stopping part 45 enlarges continuously from a rear side toward a frontal side, the stopping part 45 gradually comes to a plugged state in the guide pipe 2 when the injection pipe 3 is pulled into the guide pipe 2. Consequently, such a situation where a strong force is suddenly given to the nozzle 4 is not occur, and thus the connection strength between the nozzle 4 and the injection pipe 3 is not compromised. Therefore, the nozzle 4 can be prevented from falling off from the injection pipe 3 and remaining in a uterine body.
(77) Since the protruding parts 420 which bite into the inner surface of the injection pipe 3, and/or the recessed parts 422 which are bitten into by the injection pipe 3 (tube 30) are formed on the outer peripheral surface of the connecting cylindrical part 42, the connection strength between the injection pipe 3 and the nozzle 4 is high. Therefore, the nozzle 4 can be surely prevented from falling off from the injection pipe 3 and remaining in a uterine body.
(78) In the injector 1 of the present Embodiment, similarly to Embodiment 1, the injection pipe 3 comprises a flexible 1st pipe section 3a constituting the frontal side of the injection pipe 3, and a 2nd pipe section 3b having a rigidity higher than the 1st pipe section 3a and constituting the rear side of the injection pipe 3. More specifically, the injection pipe 3 comprises a flexible tube 30 which is longer than the guide pipe 2 and is inserted in the guide pipe 2, and a rigid sleeve 37 which is arranged so that the outside of a rear part of the tube 30 is covered with the sleeve 37, leaving a frontal part of the tube 30 in an exposed state. Therefore, in the present Embodiment, the 1st pipe section 3a is constituted by a portion of the tube 30 protruding from the rigid sleeve 37 on a frontal side, and the 2nd pipe section 3b is constituted by the rigid sleeve 37 and a portion of the tube 30 positioned inside the rigid sleeve 37. The injection pipe 3 has a reinforcing layer 33 composed of the flexible sleeve 36 which covers a boundary part between the 1st pipe section 3a and the 2nd pipe section 3b. As a result, the injection pipe 3 has a structure in which the rigidity increases in a stepwise fashion from the frontal side to the rear side. Therefore, in manipulating the injection pipe 3, buckling does not occur at the 2nd pipe section 3b, as well as similar effects as Embodiment 1 are exhibited, for example, buckling is unlikely to occur at the frontal side of the injection pipe 3.
(79) [Embodiment 4]
(80)
(81) According to Embodiments 1 to 3, in providing a reinforcing layer 33 on a boundary part between the 1st pipe section 3a and the 2nd pipe section 3b, a flexible sleeve 36 is arranged so that the outside of the tube 30 and the outside of the rigid sleeve 37 are covered with the flexible sleeve 36. In contrast, according to the present Embodiment, as shown in
(82) [Embodiment 5]
(83)
(84) According to Embodiments 1 to 4, in providing a reinforcing layer 33 on a boundary part between the 1st pipe section 3a and the 2nd pipe section 3b, a rigid sleeve 37 and a flexible sleeve 36 are arranged so that they partially overlap each other. In contrast, according to the present Embodiment, as shown in
(85) A reinforcing layer 33 may also be formed by a coating layer provided outside of the tube 30 instead of the flexible sleeve 36.
(86) [Embodiment 6]
(87)
(88) As shown in
(89) According to Embodiments 1 and 2, a reinforcing layer 33 is provided on a boundary part between the 1st pipe section 3a and the 2nd pipe section 3b of the injection pipe 3, whereas, according to the present Embodiment, such a reinforcing layer 33 is not provided. Although in the present Embodiment a constitution in which the reinforcing layer 33 is not used in an injector of Embodiment 2 is illustrated, a constitution in which the reinforcing layer 33 is not used in an injector of Embodiment 1 may also be adopted.
(90) [Embodiment 7]
(91)
(92) In the injector 1 shown in
(93) In the present Embodiment, a cylindrical joint member 390 is used as a joint 39. The frontal side of the joint member 390 in the longitudinal direction constitutes a connection part 391 which connects with the tube 30, and the rear side constitutes a connection part 396 which connects with the rigid pipe 38. The connection part 391 of the present Embodiment is a cylindrical part inserted in the tube 30, and a protruding part 392 which bites into the inner circumferential surface of the tube 30 is formed on the outer peripheral surface of the connection part 391. The protruding part 392 of the present Embodiment has a cross-sectional shape of approximately right-angled triangle with the hypotenuse facing the frontal side. Therefore, even in the case where the protruding part 392 is formed on the outer peripheral surface of the connection part 391, the connection part 391 can be easily inserted into the tube 30, and the protruding part 392 generates a strong resistance force against a force for pulling the connection part 391 out of the tube 30.
(94) The connection part 396 is a cylindrical part, on the inner circumferential surface of which a female screw 397 is formed, and the frontal end of the rigid pipe 38 is a small diameter cylindrical part 381 on which a male screw 382 that mates with the female screw 397 is formed. Since the outer diameter size of the connection part 396 is the same as the outer diameter size of the rigid pipe 38 and the outer diameter size of the tube 30, no steps occur between the joint member 390 and the rigid pipe 38 and between the joint member 390 and the tube 30.
(95) In the injection pipe 3 constituted in such a manner, the injection pipe 3 can be divided in a longitudinal direction by the joint 39 provided at any position in the longitudinal direction. Therefore, in such an injection pipe 3, a portion comprising the joint member 390 and the rigid pipe 38 may be repeatedly used after washing, whereas, a portion comprising the tube 30 and the nozzle 4 may be used only once and then discarded.
(96) The injection pipe 3 is constituted by the flexible tube 30 (1st pipe section 3a) and the rigid pipe 38 (2nd pipe section 3b) connected to the rear side of the tube 30. Therefore, in manipulating the injection pipe 3, similar effects as Embodiment 1 are exhibited, for example, buckling does not occur at the 2nd pipe section 3b. Further, since the 2nd pipe section 3b is composed only of the rigid pipe 38, the flexible tube 30 can be shortened, and thus costs for components can be reduced.
(97) The rigid pipe 38 is preferably made of a resin, rather than a metal. Since the rigid pipe 38 made of a resin has a thermal conductivity coefficient lower than the rigid pipe 38 made of a metal, a fertilized ovum(ova) or a sperm(s) passing through the rigid pipe 38 will not be chilled rapidly in carrying out the injection operation in a cold environment. Therefore, loss of the activity of a fertilized ovum(ova) or a sperm(s) due to rapid chilling can be prevented.
(98) As for the joint 39, a constitution in which the tube 30 and the rigid pipe 38 are directly connected to each other (i.e. the joint member 390 is not used) may be adopted. As for the joint member 390, a constitution in which the entire body thereof is arranged inside the tube 30 and the rigid pipe 38 may be adopted. Further, as for the joint 39, a constitution in which the tube 30 and the rigid pipe 38 are directly connected to each other undetachably with an adhesive, or a constitution in which the tube 30 and the rigid pipe 38 are each connected undetachably to the joint member 390 with an adhesive, may be adopted.
(99) [Embodiment 8]
(100)
(101) As shown in
(102) The 1st tube 30a and the 2nd tube 30b are apart from each other in an extending direction of the injection pipe 3, and an enlarged diameter space 3c having an inner diameter larger than the inner diameter size of the 1st tube 30a and the inner diameter size of the 2nd tube 30b is formed between the 1st tube 30a and the 2nd tube 30b. The injection pipe 3 comprises a sleeve 32 made of a resin or a rubber surrounding the enlarged diameter space 3c. According to the present Embodiment, as a sleeve 32, one composed of a heat-shrinkable sleeve made of a polyester resin or a poly(vinyl chloride) resin may be used. The sleeve 32 covers the outside of the the end part of the 1st tube 30a and the outside of the end part of the 2nd tube 30b to connect the end part of the 1st tube 30a with the end part of the 2nd tube 30b. Further, according to the present Embodiment, the rigid sleeve 37 covers the 2nd tube 30b entirely in a longitudinal direction, and covers also the end part of the 1st tube 30a, thereby connecting theist tube 30a with the 2nd tube 30b.
(103) By an injection pipe 3 constituted in such a manner, in a preparation stage a fertilized ovum(ova) or a sperm(s) can be supplied into the injection pipe 3 to retain the fertilized ovum(ova) or the sperm(s) temporarily in the enlarged diameter space 3c. Further, according to the present Embodiment, the enlarged diameter space 3c is surrounded by the sleeve 32 made of a resin or a rubber, and the sleeve 32 has a function for thermally insulating the enlarged diameter space 3c from the outside. Therefore, in wintertime, a fertilized ovum(ova) or a sperm(s) can be supplied into the injection pipe 3 to retain the fertilized ovum(ova) or the sperm(s) temporarily in the enlarged diameter space 3c in an indoor preparation stage, and then an injection operation can be conducted outdoors. Since the enlarged diameter space 3c is arranged at a position which is positioned in a vagina when the injector 1 is inserted deep into a bovine uterine body in an injection operation, cooling by the outside air can be avoided and therefore loss of the activity of the fertilized ovum(ova) or the sperm(s) can be avoided.
(104) [Embodiment 9]
(105)
(106) As shown in
(107) By an injection pipe 3 constituted in such a manner, effects similar to Embodiment 8 are exhibited, for example, in a preparation stage a fertilized ovum(ova) or a sperm(s) can be supplied into the injection pipe 3 to retain the fertilized ovum(ova) or the sperm(s) temporarily in the enlarged diameter space 3c.
(108) [Embodiment 10]
(109)
(110) In the injector 1 shown in
(111) In the present Embodiment, a ring shown in
(112) In attaching the ring-shaped elastic member 91 to the guide pipe 2, a structure in which a flange 21 is attached to the end part of the guide pipe 2 with the circular arc part 912 of the elastic member 91 held in the groove 210 of the flange 21 is adopted in the present Embodiment.
(113) As shown in
(114) [Other Embodiments]
(115) In the above Embodiments, injections of a fertilized ovum(ova) are mainly explained. However, the injector 1 may be used for an injection of a sperm(s) for artificial insemination. In this case, a method in which a straw 7 shown in
(116) In the above-described Embodiments, injections of a fertilized ovum(ova) or a sperm(s) to a cow are illustrated. However, the injector 1 may be used for injecting a fertilized ovum(ova) or a sperm(s) to a mammal other than a cow (typically a domestic animal). In that case, the sizes of the respective components (length, diameter, etc.) of the injector may be designed appropriately according to a target mammal.
DESCRIPTION OF SYMBOLS
(117) 1 Injector for a fertilized ovum(ova) or a sperm(s) 2 Guide pipe 3 Injection pipe 3a 1st pipe section 3b 2nd pipe section 3c Enlarged diameter space 4 Nozzle 5 Reinforcing pipe for connection 6 Cylindrical connector 7 Straw 8 Fluid supplier 9 Click mechanism 30 Tube 30a 1st sleeve 30b 2nd sleeve 35 Reinforcing sleeve 36 Flexible sleeve 37 Rigid sleeve 39 Joint 40 Connection part between a tube and a nozzle 41, 42 Connecting cylindrical part 44 Tapered surface 420 Protruding part 422 Recessed part 661 to 663 Step part