Screening apparatus and method
11678795 · 2023-06-20
Assignee
Inventors
- Dan OZ (Airport City, IL)
- Michael BELKIN (Airport City, IL)
- Ran YAM (Airport City, IL)
- Oren YEHEZKEL (Airport City, IL)
Cpc classification
A61B3/00
HUMAN NECESSITIES
A61B3/08
HUMAN NECESSITIES
International classification
A61B3/08
HUMAN NECESSITIES
A61B3/14
HUMAN NECESSITIES
Abstract
An apparatus for screening, treatment, monitoring and/or assessment of visual impairments, comprising electronic means for simultaneously applying two separate and unrelated processing methods to images presented to a patient's eyes; a first processing method being applied to an non-amblyopic eye (the eye with the better vision), and a second processing method being applied to an amblyopic eye (the weaker eye, or the impaired eye). A method for screening, treatment, monitoring and/or assessment of visual impairments, comprising: a. defining a starting point, wherein differences between a patient's eyes are completely, or as closely as practically possible, corrected, to enable two identical or similar images to be transferred to the brain from the patient's eyes; b. defining an ending point, wherein there is no correction applied to any of the patient's eyes; c. defining a screening, treatment, monitoring and/or assessment plan, for initially applying correction to images according to the starting point, then gradually reducing the correction, at a controlled and predetermined rate, towards the ending point; and d. applying the plan to images presented to the patient's eyes, while monitoring patient's performance.
Claims
1. A method for screening, treatment, monitoring and/or assessment of visual impairments, comprising: simultaneously applying two separate processing steps to images presented to a patient's eyes using electronic means, the electronic means comprising image generating means, digital image processing means, eye tracker means for measuring a direction of the patient eyes' line of sight, and display means for presenting images to both of the patient's eyes, the two separate processing steps being: a first processing step being applied to a non-amblyopic eye, and a second processing step being applied to an amblyopic eye, wherein the first processing step creates an area with a controlled measure of image degradation, where the location of the degraded area is moved responsive to the measured direction of the line of sight of the non-amblyopic eye, wherein the second processing step is continuously responsive to a measured direction of a line of sight of the amblyopic eye and the response includes, when there is deviation between the measured directions of the lines of sight of both eyes, movement of the image vertically and/or horizontally as real-time image disparity compensation based on live eye tracking data, so that as the line of sight of amblyopic eye moves vertically and/or horizontally, the presented image on the display means is moved as well, thereby ensuring that a stimulation center remains on a fovea region regardless of which direction each eye is looking; and wherein the method further comprises compensating for changes of strabismus angles with different gaze directions by the real-time image disparity compensation based on live eye tracking data.
2. The method according to claim 1, wherein the area with image degradation is so located on the display as to be presented on a fovea of the non-amblyopic eye.
3. The method according to claim 1, wherein the area with image degradation is so located on the display as to be presented on a macula of the non-amblyopic eye.
4. The method according to claim 1, wherein said second processing step includes a movement of the image vertically and/or horizontally, changing the magnification of the image (zoom in or zoom out), and/or rotation of the image.
5. The method according to claim 4, wherein said changing the image may include a movement of the image vertically and/or horizontally, changing the magnification of the image and/or rotation of the image.
6. The method according to claim 1, wherein said second processing step further comprises correcting defects of said amblyopic eye by processing the image presented thereto.
7. The method according to claim 1, wherein said second processing step further comprises stimulating the amblyopic eye with: a clear and sharp image or a high contrast image.
8. The method according to claim 1, wherein said area with a controlled measure of image degradation, the degree of image degradation is not uniform.
9. The method according to claim 8, wherein in said area with a controlled measure of image degradation, the degradation is stronger in the center of the area and is gradually reduced towards the edges of the area, to provide a smooth transition.
10. The method according to claim 1, wherein the second processing step includes changing the image so as to present 3D disparity so the patient perceives depth.
11. The method according to claim 1, wherein said first processing step and said second processing step comprise applying different complementary blobs of image to the non-amblyopic eye and the amblyopic eye.
12. The method according to claim 11, wherein said blobs are of different shapes and vary with time.
13. The method according to claim 1, wherein said first processing step and said second processing step are such that only the image presented to the amblyopic eye includes a moving object.
Description
BRIEF DESCRIPTION OF THE DRAWINGS
(1) Embodiments of the invention are disclosed hereinafter with reference to the drawings, in which:
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DETAILED DESCRIPTION OF THE INVENTION
(56) The current invention will now be described by way of example and with reference to the accompanying drawings.
(57) Remarks:
(58) a. The 3D monitor and glasses can be of any kind—e.g. passive, alternating, polarized etc.
(59) b. Monitor=display=screen (Stationary apparatus—one 3D display; Portable apparatus—one or two micro-displays)
(60) c. 3D=three-dimensional
(61) d. Near eye display=micro display
(62) e. Fellow eye=non amblyopic eye (the better, stronger eye).
(63) A Apparatus for Simultaneously Measuring and Treating One or More Vision-Related Diseases, Using Separate Processing Methods for Each Eye
(64) For example, the image presented to each of patient's two eyes undergoes a different processing:
(65) a. For the non-amblyopic eye, the processing includes an area with a controlled measure of image degradation, to cause the patient to rely more on the other, weaker eye; furthermore, the location of the degraded area is moved on the screen responsive to the measured direction of the line of sight of the non-amblyopic eye;
(66) b. For the amblyopic eye, the processing includes changing the image so as to present identical or as similar as possible images to the two eyes, to allow combining the images in the brain.
(67) Processing may include a movement of the image vertically and/or horizontally, changing the magnification of the image (zoom in or zoom out), and/or rotation of the image.
(68) The processing is responsive to the measured direction of the line of sight of the amblyopic eye—That is, as the line of sight moves vertically and/or horizontally, so the presented image on the screen is moved as well.
(69) Gradual image degradation: for the non-amblyopic eye, the measure of image degradation needs not be uniform in the area with image degradation; preferably, the degradation is stronger in the center of that area, and is gradually reduced toward the edges of the area, to provide a smooth transition.
“On the Go” Real Time Treatment
(70) The patient can receive treatment as he works, during recreation, etc. The patient wears goggles with means for capturing real-time images, a processor for processing the image to one eye or both according to predefined settings adapted to that patient's illness, and display means for presenting the processed image(s) to the patient's eye(s). This embodiment may save patient's time, and is easier to perform. Rather than visiting a clinic, waiting and receiving treatment, the patient receives treatment while he/she is doing other tasks.
(71) Using True Tri-Dimensional (3D) Images for Measurement and Treatment
(72) True 3D images best stimulate the brain to combine the images, so the patient perceives the depth of each object in space—an essential benefit, which people with normal healthy vision may fail to fully appreciate. 3D perception is a precious and frangible skill, which can be easily lost when there are vision problems.
(73) The present invention uses an innovative concept to achieve this benefit, including:
(74) a. Using true 3D images, that is images generated from two cameras, separately located so they will “see” the world just like two normal eyes, which are separately located, would see the world. The images from the two cameras are not identical but contain some tiny differences; these differences are used by the brain to reconstruct the 3D scene.
(75) b. Correcting the defects of the weak eye by processing the image presented thereto, so the brain will perceive identical, or as close to identical as possible, images from the two eyes; this allows the brain to combine the two images into one 3D object.
(76) A digital processor is used to change the image to one eye by moving of the image vertically and/or horizontally, changing the magnification of the image (zoom in or zoom out), and/or rotating the image.
(77) c. Challenging/stimulating the patient to rely more on the weaker eye, by a controlled degradation of the image presented to the stronger (better vision) eye.
(78) Adaptive Method for Screening, Treatment, Monitoring and/or Assessment of Visual Impairments
(79) The method includes:
(80) a. defining a starting point, wherein differences between a patient's eyes are completely, or as closely as practically possible, corrected, to enable two identical or similar images to be transferred to the brain from the patient's eyes; b. defining an ending point, wherein there is no correction applied to any of the patient's eyes; c. defining a screening, treatment, monitoring and/or assessment plan, for initially applying correction to images according to the starting point, then gradually reducing the correction, at a controlled and predetermined rate, towards the ending point; and d. applying the plan to images presented to the patient's eyes, while monitoring patient's performance; e. adjusting the rate of change of the correction responsive to results of monitoring the patient's performance; f. defining a range of desired rate of improvement with minima and maxima, during monitoring comparing actual patient's performance with the desired rate of improvement, and issuing a report or a warning if the actual performance exceeds the range of desired rate of improvement.
The Above Method can be Applied to any of the Embodiments of the Apparatus Disclosed in the Present Invention.
Combining the Above Main Features in Many Variations, and Adjusting the Parameters of the Digital Processing, so as to Best Fit the Visual Problems of Each Patient
(81) The apparatus in the present invention is modular and flexible; it is software-controlled, to achieve a very powerful and useful apparatus for Screening, Diagnosing, Assessing, Monitoring and Treating Eye Diseases and Visual Impairments.
(82) Notes:
(83) 1. It is essential to distinguish between
(84) (a) Using true tri-dimensional (3D) images for measurement and treatment, on the one hand, and
(85) (b) 3D display devices, such as 3D glasses, etc.
(86) The feature (a) is an essential part of the present invention, and relates to 3D images creation, separate processing for each eye and separate display to each eye;
(87) Whereas (b) relates to prior art equipment for presenting separate images to each eye.
(88) The present invention uses 3D devices in (b) to present a different, separate image to each eye; but this is just one component of the apparatus and method presented in (a).
(89) 2. Contemporary digital processors offer means for powerful image processing, in small packages and at low cost. This facilitates making a portable, “On-the-go” apparatus.
(90) One example of such a processor is the 32 bit PIC32MZ Family of High performance microcontroller with Floating point Unit (FPU) and an advanced peripheral set, manufactured by Microchip Technology Inc.
(91) Hardware
(92) We will describe here examples of 3 embodiments, all based on similar principles and sub-assemblies: Stationary Apparatus based on PC, laptop etc., for home or office use; Portable apparatus based on tablet, smart phone etc. for home, office or screening; Portable apparatus based on goggles with micro-displays for home, office or “on the go” use.
(93) In all the embodiments, either stationary or portable, corrective lenses, if required, might be added. In the portable apparatus based on goggles, a special fitting for the addition of corrective lenses might be added to the goggles frame or directly integrated into the provided eye pieces' lenses.
(94) In addition, the images will be provided separately for both eyes in such accommodation/convergence properties as required for near or far vision. The principle of operation is as described in our international patent application No. PCT/IL2016/050232.
(95) In addition, a microphone can be added with appropriate voice recognition software for getting patient response to various stimuli, measurements of reading speeds etc. The microphone is depicted only in
(96) Stationary Apparatus
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Also shown are a patient 1 and two dichoptic images 31.
The apparatus block diagram is depicted in
Also shown are the eye tracker data 41, display signals 32, patient's left eye 13 and right eye 12.
The processor 5 controls the 3D glasses 2 (if required) and sends the required and processed two dichoptic images (either stationary pictures, video, games etc.) to the 3D display 3. In addition, the processor receives the eyes' gazing direction from the eye tracker 4 and all required controls from the input devices such as the keyboard, mouse etc.
Portable Apparatus Based on Tablet
(98) Instead of a PC, the apparatus can use a tablet (such as an iPad) or a smart phone with an eye tracker. The eye tracker can be replaced by the integrated tablet/phone camera to serve as an eye tracker.
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(100) Portable Apparatus with Goggles
(101) The goggles embodiment comprises the following parts, see
The above detailed parts (possibly with the exclusion of the processor 6) may be mounted on a portable binocular or monocular frame 39
A monocular apparatus includes one micro display, one scene camera and one ocular optics, see
The ocular sub-assembly may include corrective optics if required by the patient.
The apparatus includes right scene camera 71, left scene camera 72, right near eye display 34, left near eye display 35, right eye near tracker 45, left eye near tracker 46 and eyepiece lens 38. Also shown are patient's right eye 12 and left eye 13.
The processor sends the required two dichoptic images (either stationary pictures, video, games, etc.) to the micro-displays—see a block diagram for binocular apparatus in
(102) The Control Box/Processor is not shown on these figures. In addition, the processor receives the eyes' gazing direction from the eye trackers and all required controls from the input devices such as the keyboard or control buttons on the goggles etc.
(103) If required, the scene cameras capture the scene in front of the patient, processed accordingly by the processor to be displayed on the micro displays.
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(105)
(106) Principles of Operation
(107) Principles of Operation for Amblyopia Treatment
(108) The main requirement for amblyopia treatment is to prevent the amblyopic eye/brain apparatus from deterioration causing a permanent & incurable vision decrement. This must be accompanied (not the subject of the present invention) and in parallel, by addressing the cause for amblyopia. The processes enforce the brain to use the amblyopic eye.
(109) In our apparatus, we enforce the brain to use the amblyopic eye but we do provide appropriate stimulation for the non-amblyopic eye as well, in order to train the stereopsis process and preserve the binocular vision and depth perception.
(110) In order to overcome the problems of existing treatment options as mentioned above, our apparatus will work as follows: The professional (ophthalmologist or optometrist) will determine the required type of stimulation. It can be either stationary pictures, video, games, normal scenery etc. Following are few examples: Stimulating only the amblyopic eye for a certain percentage of time. The fellow eye does not receive any stimulation Stimulating the amblyopic eye with a clear and sharp image while providing the fellow eye with a blur image either by degeneration of sharpness, intensity, details etc. Providing different segments of the image to each eye separately Providing different locations of the right/left images in order to compensate for Strabismus in case of strabismic amblyopia The images might be provided separately for both eyes in such accommodation/convergence properties as required for creating virtual near or far image. The principle of operation is as described in our international patent application No. PCT/IL2016/050232. The eyes tracker ensures that the stimulation center remains on the fovea region no matter in which direction each eye is looking at. The method will provide treatment while the child is playing PC games, watching video etc.
Principles of Operation for Convergence Deficiency Diagnosis & Treatment and Heterophoria Treatment
(111) The main requirement for convergence deficiency diagnosis is to provide variable convergent images, beginning with relatively apart images which does not require the eyes to converge and gradually moving in the 2 images until the eye trackers will inform the processor that the eyes stopped converging.
(112) The main requirement for convergence deficiency treatment is to provide variable convergent images, beginning with relatively apart images which does not require the eyes to converge and gradually moving in the 2 images to train them to converge.
(113) In order to overcome the problems of existing treatment options as mentioned above, our apparatus will work as follows: The professional (ophthalmologist or optometrist) will determine the required type of stimulation. It can be either stationary pictures, video, games, normal scenery etc. Following are few examples: The images will be provided separately for both eyes in such convergence properties as required for creating virtual near or far image. The principle of operation is as described in our international patent application No. PCT/IL2016/050232, hereby included by reference. The eyes tracker ensures that the stimulation center remains on the fovea region no matter to which direction each eye is looking at.
The same treatment can be performed for patient suffering from heterophoria.
Main Processes/Methods
Amblyopia Treatment
(114) The process implemented in the various embodiments are similar. The description hereinafter is united and the differences are mentioned.
(115)
(116) Step #1
(117) The processor obtains the required images from the training program. The image source can be either stationary pictures, video, games, normal scenery etc. 801
(118) Step #2
(119) The processor performs required image processing on the images. Following are some examples (There can be many more ways) 802:
(120) High contrast for amblyopic eye and low contrast for fellow eye (see
Any combinations of the above examples can be used in training.
The various parameters of every example could be changed and adjusted for the patient.
In all above, the training should be designed carefully, taking care that suppressing the good eye will not cause it to become amblyopic (reverse amblyopia).
(121) Step #3
(122) The processor receives each eye gazing direction from the eye trackers. 803
(123) Step #4
(124) The processor calculates the location on the screens 804. If the 2 eyes of the patient are parallel, the 2 images for both eyes should be displayed exactly on the same location on the monitor. Each eye will perceive each identical & relevant part of the picture exactly on the fovea. The brain will combine these 2 images into one 3D image, see
(125) Let's assume now that the 2 eyes of the patient are not parallel, e.g. the patient suffer from strabismus. If we display the images in parallel, as shown in
(126) Our device will determine the relative gazing direction of each eye. Let's assume again that the 2 eyes of the patient are not parallel, e.g. the patient suffers from strabismus. We shift the image for the strabismic eye in such a way that its interest area will be projected exactly on the fovea. The non strabismic eye will also see the interest location of the image exactly on the fovea. The total perceived image will be combined by the brain and produce a single, normal 3D image, see
(127) Since we use eye trackers, the apparatus will compensate for any type of eyes' deviation, either concomitant (non-paralytic) or incomitant (paralytic) strabismus.
(128) For strabismic eyes, a similar process will be applied in similar way for near sight training as explained above.
(129) Step #5
(130) The processor will display the 2 processed images on the proper location on the display and the process will continue during the whole training session. 805
(131)
(132)
One goal of our invention is to correct the images presented to one eye or both eyes, by changing the location of the images presented on the retina, so identical or similar images appear on the same location as shown with corrected images 311, 312 in both eyes. The same size images will be correctly combined in the brain into one image 321 (a tri-dimensional image if the original images 301, 302 pertain in a 3D object).
One goal of our invention is to correct the images presented to one eye or both eyes, by changing the location of the images presented on the retina 301 and 302, so identical or similar images appear on the same location as shown with corrected images 311, 312 in both eyes. The same size images will be correctly combined in the brain into one image 321 (a tri-dimensional image if the original images 301, 302 pertain in a 3D object).
Convergence Insufficiency Diagnosis
The processes implemented in the various embodiments are similar. The description hereinafter is united and the differences are mentioned, if exist.
(133) Step #1
(134) The processor obtains the required images from the training program and display them on the display in the initial, non-converging locations. The image source can be either stationary pictures, video, games, normal scenery etc. See
(135) Step #2
(136) The eye trackers track the eyes and inform the processor whether the eyes tracked the image. 812
(137) Step #3
(138) If the eyes tracked the image, the process will go to step 4. If the eyes did not track the image, the process will go to step 5. 813
(139) Step #4
(140) The images will “move in”, for example by additional 1 degree. 814. See also
(141) Step #5
(142) If the eyes did not track the images, the perceived images will be as seen in
(143) Step #6
(144) End of process, the process might be repeated a few times in order to average and get more accurate results. 816
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(148) One goal of our invention is to correct the images presented to one eye or both eyes, by changing the location of the images presented on the retina 301 and 302, so identical or similar images appear on the same location as shown with corrected images 311, 312 in both eyes. The same size images will be correctly combined in the brain into one image 321.
Convergence Insufficiency and Heterophoria Treatment
(149) The treatment will be performed as detailed above with reference to “Convergence Insufficiency Diagnosis”, with the following changes:
(150) Once the convergence insufficiency will be determined, the addition of “moving in the image” will stop just before the eyes will lose the image tracking and the training will repeat according to the training program, for example, 15 minutes a day. The diagnosis process will be initiates occasionally and if a progress will be detected, an addition of 1 degree, for example, will be added to the images “move in” parameters.
In order to improve efficiency of the treatment, the exercise may be continued even beyond optimal convergence to achieve a better training for the child.
Monitoring and Assessment
The apparatus can measure, at regular intervals and during routine exercises, various parameters such as: Visual acuity Strabismus angle and extent of heterophoria Extent of stereopsis Color Blindness Test Convergence insufficiency diagnosis Eye movements: saccades speeds, trajectory and reaction time, vestibulo-ocular reflex measurements Optokinetic reflex measurements Reading speed Pupil testing
Based upon the results, the apparatus will assess the progress of the patient and: Recommended changes in the treatment program Provide a feedback signal to the trainee Automatically change the treatment program.
Visual Acuity Test
The automatic test can be performed in several ways. One example is explained in detail below. The test may be performed using “Gabor Patch” images, see
The process is based on a technique called “Teller Acuity Cards” which is a known practice in ophthalmology to measure the visual acuity of small children.
The Gabor Patch can be modified by various parameters. For example: Spatial frequency—changing the distance between adjacent lines—see
Our apparatus performs the test automatically by changing the various parameters of the patch while tracking the eye and determining whether the eye tracks the patch or not. In addition, performing this test manually with cards is done statically—typically the pattern will be displayed either in the left side or right side of the visual field. Our apparatus provides the location dynamically in any area of the field of view.
We will present herein a test performed for a single eye. This process can similarly be performed for the second eye as well.
Since the test has to be performed to each eye separately, the non-tested eye has to be occluded. This can be done either by a mechanical occlusion as performed today in conventional visual acuity tests or by using 3D display and 3D glasses as described throughout this document. In the case of goggles portable embodiment, this will be performed by projecting the image only to the tested eye.
Step 1—The Gabor image (initially with low spatial frequency and high contrast) is moved to a location on the display. 821
Step 2—Track the eyes with the eye tracker and provide the data to the processor. 822
Step 3—The processor will determine whether the eye tracked the target. If the eye was tracking the Gabor Patch the process will move to step 4. If the eye will not be able to see and/or track the patch, the process will go to step 5. 823
Step 4—The patch parameters will become harder to track by increasing the spatial frequency (the bars become progressively finer or closer together), by decreasing the contrast, by increasing the patch movement speed and so on, provide a new location and go back to step 1. 824
Step 5—The processor will calculate the visual acuity based on the last tracked patch and standard existing tables that correlate that patch to the relevant visual acuity. 825
The test can be conducted with other images than the Gabor Patches by providing more attractive targets for children like animals, cartoon heroes, symbols etc.
The images can be stationary on different parts of the screens or moving in various speeds while the eye trackers determine whether the eyes follow the targets.
The image might be shown with different orientations and by checking the tracking ability of the different orientations, an information about possible astigmatism and the astigmatism axis might be gathered.
Step 6—End. 826
Strabismus and Heterophobia Test
(151) The strabismus test is performed as described in our international patent application No. PCT/IL2016/050232, hereby included by reference.
(152) Stereopsis Depth Test
(153) Stereopsis is the process of perception of depth and 3-dimensional structure obtained on the basis of visual information derived from two eyes. Because the eyes of humans are located at different lateral positions on the head, binocular vision results in two slightly different images projected to the retinas of the eyes. The differences are mainly in the relative horizontal position of different objects in the two images. These positional differences are referred to as horizontal disparities. These disparities are processed in the visual cortex of the brain to yield depth perception.
(154) While binocular disparities are naturally present when viewing a real 3-dimensional scene with two eyes, they can also be simulated by artificially presenting two different images separately to each eye. The perception of depth in such cases is also referred to as “stereoscopic depth”.
(155) A person perceives 3D impression not only by the horizontal disparities effect of binocular vision, but also by monocular clues such as relative objects size, relative motion and more.
(156) Our automatic test can be performed in several ways. One example is explained in detail below.
(157) Prior Art Method:
(158) The test example shown here has no monocular clues thus provides a reliable assessment of stereo-acuity resulting from binocular disparity and stereopsis process performed in the visual cortex.
(159) The test is based on Random Dot Stereograms (RDS)—see
(160) A part of these 2 images is horizontally shifted so as to create the required spatial difference in such a way that when viewed by both eye separately, produces the perception of depth, with objects appearing to be in front of or behind the display level. See an example of a square as perceived by a person with normal depth perception—
(161) A person with no depth perception, or a normal person looking with only a single eye, will see just randomly dots as depicted in
(162) The shapes can be of any kind—letters, geometrical, animals etc., in colors or black and white and so on.
(163) The disparity of the relevant part in the images can vary, according to standard values used in current procedures, for example, from 4,800 to 12.5 seconds of arc. The lower the disparity recognized as being seen as 3D image by the tested person, the better his stereo-acuity.
(164) Our Apparatus:
(165) Our apparatus performs the test automatically by creating RDSs and moving the target image from side to side on predetermined paths and predefined speeds while the eye trackers determine whether the eyes follow the targets or not.
(166) As the patient tracks appropriately the target, the horizontal disparity of the target image will gradually change from highest disparity to a lower disparity until the eye tracker will determine that there is no tracking any more. If the patient does not have depth perception, he will not be able to track the target.
Our method to display the 2 images to each eye separately is performed as explained throughout this document.
Step 1—Display an RDS target with high disparity (in initialization phase) and move it on the screen. 831
Step 2—Track the eyes with the eye tracker and provide the data to the processor. 832
Step 3—The processor will determine whether the eye see/tracked the target along its path. If the eye was tracking the 3D target the process will move to step 4. If the eye will not be able to see and/or track the target, the process will go to step 5. 833
Step 4—The target disparity parameters will decrease and go back to step 1. 834
Step 5—The processor will calculate the stereo-acuity based on the last tracked target disparity and standard existing tables that correlate that last disparity to the relevant stereo-acuity. 835
Step 6—End. 836
The test can be conducted with other images than the geometric shapes by providing more attractive targets for children like animals, cartoon heroes, symbols etc.
Color Blindness Test
(167) Color blindness affects about 8% of men and 0.5% of women.
(168) Prior Art Method:
(169) An example of the most popular test are the Ishihara plates. The test consists of 38 different pseudo isochromatic plates, each of them hides a number or shape behind colorful dots. Based on what you can see and what not, it is possible to check if you are suffering from some form of color blindness. The cooperation of the subject is needed for informing what number or shape he sees.
(170) In the following picture we show an example of Ishihara plate. For practical reasons of patent drawings, we show the drawings only in gray scale. However, the color plates are very common and any one skilled in the art is aware of the real color plates.
(171)
(172) The depth of color perception can be tested by altering the various intensities, contrasts and different sizes.
(173) A normal person will see a color ring 304 as shown in
(174) Our Apparatus:
(175) Our new apparatus and method performs the test the color perception depth automatically. It will create a target shape that will attract the eyes (for example, for a small child a shape of a bear) and move the target image on the display at predetermined paths and speeds (See example in
(176) As the patient tracks appropriately the target, the intensity, contrast and size of the dots will gradually change from higher intensity, contrast and size to a lower intensity, contrast and size until the eye tracker will determine that there is no tracking any more.
(177) The point where the person's eyes will stop tracking will be indicative of his/her color depth perception.
(178)
(179) Step 1—Display a color blindness target with high intensity, contrast and size (in initialization phase) and move it on the screen. 841
(180) Step 2—Track the eyes with the eye tracker and provide the data to the processor. 842
(181) Step 3—The processor will determine whether the eye see/tracked the target along its path. If the eye was tracking the color blindness target the process will move to step 4. If the eye will not be able to see and/or track the target, the process will go to step 5. 843
Step 4—The color blindness parameters will decrease and go back to step 1. 844
Step 5—The processor will calculate the color blindness score based on the last tracked target color contrast. 845
Step 6—End. 846
The test can be conducted with other images than the geometric shapes by providing more attractive targets for children like animals, cartoon heroes, symbols etc.
Eyes' Dynamics Test
In this test, the apparatus measures several parameters: Saccades initiation delays Saccades speeds and trajectory Smooth pursuit tracking quality Vestibulo-ocular reflex Optokinetic reflex
Saccades Delays, Speeds and Trajectory Measurements
In the following pictures we show the display for a single eye. A target will be presented on the display and will abruptly change its position. It will jump from the left down side of the display to the right up position. See
The test image 306 is shown first in one location as shown in
The typical movement of the eye for this kind of stimulus is shown in
Initially the test image 306 is displayed in a first location, as shown in
After the stimulus is applied at time 321 (the test image 306 is moved to its second location as shown in
The eye tracker in the embodiment will track the eye and will determine whether the velocities, average and peak, are normal or were improved, deteriorated or unchanged from previous measurements, see
The eye tracker in the embodiment will track the eye and will determine whether the initiation delay (latency) of the saccadic initiation latency is normal, was improved, deteriorated or unchanged from previous measurements, see
The graphs in
In
Furthermore, the shape of the abnormal eye trajectory will enable the option to provide a patient's condition e.g. what muscles or nerves, if any, might be impaired.
Smooth Pursuit Tracking Quality Measurements
In the following pictures we show the display for a single eye. In the following pictures the arrow is not a part of the stimulation.
A target will be presented on the display and will move in a constant speed from the left down side of the display to the right up position, see
The target moves on the display along the path 307.
The typical movement of the eye for this kind of stimulus is shown in
The graph shows eye angle variation vs. time, indicating the target motion onset 308, target catch-up 309, then pursuit until the target motion end 310.
(182) As mentioned above for saccades trajectories, the eye tracker in the embodiment will track the trajectory of the eye and will determine whether the trajectory is normal, abnormal, was improved, deteriorated or unchanged from previous measurements. An example of abnormal smooth pursuit eye trajectory is depicted in
(183) Furthermore, the shape of the abnormal eye trajectory will point out which muscles out of the 6 extra-ocular muscles is malfunctioning.
(184) Vestibulo-Ocular Reflex Measurements
(185) A fixed target will be presented for the patient on the embodiment display. The patient head will be abruptly or smoothly rotated, either by himself or by another person to the side, as shown in
(186) In this kind of stimulus, the eyes of a normal patient should remain fixed on the target as shown on the right side of
(187) The eye tracker in the embodiment will track the trajectory of the eye and will determine whether the trajectory is normal, abnormal, was improved, deteriorated or unchanged from previous measurements. An example of abnormal eyes trajectory is depicted on the
(188)
(189) In the above mentioned cases, a head position tracker will add accuracy to the apparatus. This head tracker could be a commercial device type used in video games and virtual reality. Furthermore, the shape of the abnormal eyes trajectory will help the professional in the diagnostics of the reason for the case, either the ocular or the vestibular apparatus.
(190) Another embodiment uses both remote eye trackers and near eye trackers, to compute the head movements therefrom. The remote eye trackers measures eyes line of sight direction relative to a fixed platform, whereas near eye trackers measures eyes line of sight direction relative to the patient's face. The difference between these measurements gives the direction of the patient's head.
(191) Optokinetic Reflex Measurements
(192) The optokinetic reflex is a combination of a saccade and smooth pursuit eye movements. It is seen when an individual follows a moving object with his eyes, which then moves out of the field of vision at which point their eye moves back to the position it was in when it first saw the object and so on. It is used to test visual acuity in preverbal and young children.
(193) A standard apparatus for this measurement consist of a rotatable drum with vertical line as shown in
(194)
(195) The drum is rotated and the patient track the stripes from left to right with smooth pursuit movement. As the eyes reaches the right gaze limit, the eyes return to their initial position with a saccade movement and so on.
(196) The existing drum is a mechanical device on which is difficult to change spatial frequency and contrast of the stripes or to keep required speed. Our embodiments will present the targets not on a drum but on the display. The stripes will continuously move, for example, from left to right, see
(197)
(198)
(199) Pursuit 315 occurs while the eye follows a horizontally moving stripe; saccade 317 occurs when the eye jumps to another stripe to follow.
(200) An abnormal eye trajectory, in which the saccades are too slow, is depicted in
(201)
(202) The difference is that in this case, the saccade 316 is slow, indicating a problem with the eye in performing this task.
(203) Another way for the use of optokinetic reflex is the to analyze and the visual acuity and contrast sensitivity.
(204) This is done by gradually increasing the speed or the spatial frequency of the stripe as seen in
(205) In preferred embodiments, the eye tracker will track the trajectory of the eyes.
(206) The stripes become harder to track by increasing the spatial frequency (the stripes become progressively finer or closer together and/or by increasing speed), by decreasing the contrast and so on until the eyes will not be able to continue tracking. The eye tracker will determine when the eyes stop tracking.
(207) The processor will calculate the visual acuity based on standard tables that correlate that Stripe's frequency, density and contrast to the relevant visual acuity. This information is especially pertinent to visual acuity measurements in pre-verbal children.
(208)
(209) The difference from the stripes shown in
(210) Reading Speed
(211) By tracking the speed of reading (typically possible from the age of 6 or so) as measured by the eye tracker, important parameters about the reading factors such as fixation stability and saccade accuracy could be gathered in addition to the reading speed measurement by itself (which is an important parameter to the child cognitive development). The reading speed will be determined with a built in microphone and voice recognition software (well known in the art) that will compare the reading of the patient with the displayed words for correctness.
(212) Pupil Tests
(213) Pupil tests can point out various problems such as retinal, neurologic or other diseases. The eye trackers provide instantaneous pupil size and location and the apparatus performs the test according to the following table. If normal results are not obtained, the apparatus informs the operator about the discrepancies.
(214) TABLE-US-00001 Test Stimulation Normal Results Pupil shape and Normal light intensity Pupils should be round, same size at rest on display size, symmetrical and centered within the iris Direct response High light intensity to Constriction of the single eye illuminated pupil Consensual High light intensity to Constriction of opposite pupil response single eye Accommodation Near view target Constriction of pupils response
Screening
(215) The apparatus will be used for screening people, especially small children and infants for vision deficiency.
(216) All kinds of proposed embodiments can be used to perform the task. Following are example of some task:
(217) Visual acuity Strabismus angle and extent of heterophoria Extent of stereopsis Color Blindness Test Convergence insufficiency diagnosis Eye movements: saccades speeds, trajectory and reaction time, vestibulo-ocular reflex measurements Optokinetic reflex measurements Reading speed Pupil testing.
(218) The apparatus performs the same tasks as for monitoring and assessment (see description above) compares it to a standard model for reporting of possible problems that requires more thorough examination by a specialist.
(219) Since the apparatus would be used in such a case for screening purposes by non-specialist operators, the apparatus and application might be modified in such a way as to maximize speed and comfort of the test on the expense of accuracy.
(220)
(221) The difference from the stripes shown in
(222) The moving stripes shown in
(223) Adaptive Method for Screening, Treatment. Monitoring and/or Assessment of Visual Impairments
(224) Note: The method can be applied to any of the embodiments of the apparatus disclosed in the present invention.
(225) The method includes:
(226) a. defining a starting point, wherein differences between a patient's eyes are completely, or as closely as practically possible, corrected, to enable two identical or similar images to be transferred to the brain from the patient's eyes. The required correction is based on results of measuring the characteristics of the patient's eyes. b. defining an ending point, wherein there is no correction applied to any of the patient's eyes. The ideal or ultimate goal of the treatment is to correct the defects in the patient's eyes, so he/she can function without an external support apparatus. The goal may or may not be reached, depending on the patient capabilities; however, in any case the invention helps in improving a patient's vision or at least to prevent or minimize a possible deterioration following an operation, for example. c. defining a screening, treatment, monitoring and/or assessment plan, for initially applying correction to images according to the starting point, then gradually reducing the correction, at a controlled and predetermined rate, towards the ending point; and d. applying the plan to images presented to the patient's eyes, while monitoring patient's performance.
Further optional improvements to the method may include: e. Adjusting the rate of change of the correction responsive to results of monitoring the patient's performance. That is, if monitoring shows the patient's progress is slower than initially estimated, then the rate of change may be reduced, so we aim at a more modest, but attainable, goal. f. The correction may includes a movement of the image vertically and/or horizontally, changing the magnification of the image (zoom in or zoom out), and/or rotation of the image. g. Changing the plan for screening, treatment, monitoring and/or assessment responsive to results of monitoring the patient's response to applying the plan thereto. This step may be applied if monitoring shows that the patient is not responding to the initial planned strategy. A different strategy may be tried out. It is impossible to know in advance how a patient may respond to treatment. h. Defining a range of desired rate of improvement with minima and maxima, during monitoring comparing actual patient's performance with the desired rate of improvement, and issuing a report or a warning if the actual performance exceeds the range of desired rate of improvement. This step may be applied in case of failure of the previous attempts at adapting the treatment to that patient. Maybe a professional may devise a better plan for that patient, maybe additional tests are required or an intervention, etc.
Method 2 for Convergence Insufficiency Diagnosis. Main Process
1. Measure patient's eyes. Performed by professional, the measurement preferably includes as many as possible ailments of the eye. Each eye is measured separately, and the performance of both eyes together is measured as well. 851
2. Devise a convergence insufficiency diagnosis plan. 852
The plan includes: a. defining a starting point, wherein differences between a patient's eyes are completely, or as closely as practically possible, corrected, to enable two identical or similar images to be transferred to the brain from the patient's eyes; b. defining an ending point, wherein there is no correction applied to any of the patient's eyes; c. defining a diagnosis plan, for initially applying correction to images according to the starting point, then gradually reducing the correction, at a controlled and predefined rate, towards the ending point. d. set the initial values for the correction to the images presented to the eyes, according to the starting point of the plan.
3. Perform a stage of the diagnosis process: a. apply a correction to the images presented to the eyes, according to the present values for correction, and present the images to the patient's eyes. 853 b. challenge the eyes, for example by moving a picture across the screen; c. measure, using eye trackers, whether the eyes follow the movement. d. Log/record the results of the measurement, together with the relevant parameters.
4. Success? Do patient's eyes perform the required task? 854
5. Decide what to do: 855 a. If failure at the initial stage—the first time the test is applied to the patient's eyes, the plan should be revised and/or the equipment checked:
Maybe the initial images correction is not satisfactory, probably because of insufficient testing of the patient's eyes.
Maybe the test equipment needs to be verified and/or adjusted. Exit test. b. If failure after just one change in the initial parameters, maybe the increment was too large. The test may be restarted, with a slower progress—a smaller change in the image processing after each iteration. Continue test, Goto 853. c. If failure after more than one change in the initial parameters, then it is indicative of the patient's convergence insufficiency (CI). From the last value of parameters where patient's eyes did perform the required task, compute the patient's CI. Exit test. d. If the test reached the ending point in the plan (this is indicative of a perfectly normal vision, without any aids)—report this fact, and Exit test.
6. Increase the level of difficulty of the test, by reducing the correction of the images presented to the patient's eyes. 856.
The reduction—according to the plan devised in 852.
If the test reached the ending point in the plan (this is indicative of a perfectly normal vision, without any aids), GOTO End 855.
(227) It will be recognized that the foregoing is but one example of an apparatus and method within the scope of the present invention and that various modifications will occur to those skilled in the art upon reading the disclosure set forth hereinbefore, together with the corresponding drawings.