METHOD FOR IMAGING OF NONLINEAR INTERACTION SCATTERING
20170343656 · 2017-11-30
Inventors
Cpc classification
A61B5/0059
HUMAN NECESSITIES
G01S7/52038
PHYSICS
G01S7/4802
PHYSICS
G01S7/41
PHYSICS
International classification
Abstract
1.sup.st and 2.sup.nd pulsed waves (103, 104) with 1.sup.st and 2.sup.nd center frequencies are transmitted along 1.sup.st and 2.sup.nd transmit beams so that the 1.sup.st and 2.sup.nd pulsed waves overlap at least in an overlap region (Z) to produce nonlinear interaction scattering sources in said region. The scattered signal components from at least the nonlinear interaction scattering sources are picked up by a receiver (102) and processed to suppress other components than said nonlinear interaction scattered signal components, to provide nonlinear interaction measurement or image signals. At least a receive beam is scanned in an azimuth or combined azimuth and elevation direction to produce 2D or 3D images of said nonlinear interaction scattering sources.
Claims
1. A method for measurement or imaging of nonlinear interaction scattering between two waves in a material object with nonlinear material parameters that produce wave scattering, comprising the steps of a) transmitting at least one transmit event comprising i) at least one 1.sup.st transmit pulsed wave with a 1.sup.st transmit time and a 1.sup.st transmit center frequency along a 1.sup.st transmit beam with a 1.sup.st transmit direction, and ii) at least one 2.sup.nd transmit pulsed wave with a 2.sup.nd transmit time and a 2.sup.nd transmit center frequency along a 2.sup.nd transmit beam where said 1.sup.st transmit beam crosses said 2.sup.nd transmit beam in an elevation direction at an angle θ between the forward propagation directions of the beams where θ is in the range (20 -340) deg, and where the 1.sup.st and 2.sup.nd transmit beams and 1.sup.st and 2.sup.nd transmit times are arranged so that the pulses from the 1.sup.st and 2.sup.nd pulsed waves overlap in space in an overlap region Z, and b) selecting one or both of i) the time relation between said 1.sup.st and 2.sup.nd transmit times, and ii) the pulse length of at least one of the 1.sup.st and 2.sup.nd transmit pulses, to control the depth location and dimension of said overlap region Z of nonlinear interaction between said 1.sup.st and 2.sup.nd pulsed waves that produces nonlinear interaction scattering within the object, and c) receiving at least scattered wave components from the overlap region Z with at least one receiver and generating at least one receive signal that includes at least nonlinear interaction scattered signal components that relate to waves that are scattered from the nonlinear interaction between said 1.sup.st and 2.sup.nd pulsed waves in said overlap region, and d) processing said at least one receive signal to extract the nonlinear interaction scattered signal components to form nonlinear interaction measurement or image signals from said nonlinear interaction region.
2. A method for measurement or imaging according to claim 1, where the process to extract nonlinear interaction signal components includes temporal frequency filtering of the receive signal where said filtering passes said nonlinear interaction scattered signal components and blocks other temporal frequency components.
3. A method for measurement for imaging according to claim 1, where a) said transmitting step comprises at least two transmit events where said 1.sup.st and 2.sup.nd transmit beams and the time lag between said 1.sup.st and 2.sup.nd transmit times are the same for said at least two transmit events, and where b) one of said 1.sup.st and 2.sup.nd pulsed waves is varied in at least one of polarity, amplitude, phase and frequency between said at least two transmit events, including the possibility that at least one of said 1.sup.st and 2.sup.nd pulsed waves has zero amplitude for at least one of said transmit events, and where c) the process to extract nonlinear interaction scattering signal components includes combining of the receive signals from said at least two transmit events.
4. A method for measurement or imaging of nonlinear interaction scattering according to claim 3, where the center frequency of said 1.sup.st pulsed wave is less than ⅓ of the center frequency of said 2.sup.nd pulsed wave.
5. A method for measurement or imaging of nonlinear interaction scattering according to claim 3, where at least one of the receive signals from said at least two transmit events are delay corrected before combining of the receive signals from said at least two transmit events.
6. A method for measurement or imaging of nonlinear interaction scattering according to claim 3, where the process to extract nonlinear interaction scattering signal components in addition includes temporal frequency filtering of the receive signal where said filtering passes said nonlinear interaction scattered signal components and blocks other temporal frequency components.
7. A method for measurement or imaging of nonlinear interaction scattering according to claim 1, where said angle θ is any angle in the interval (160 -200) deg.
8. A method for measurement or imaging of nonlinear interaction scattering according to claim 6, where said angle θ is so much different from 180 deg that one of, i) the 1.sup.st transmitted pulse hits the receive array at an angle with reduced sensitivity of the receive array, and ii) passes outside the receive array.
9. A method for measurement or imaging of nonlinear interaction scattering according to claim 1, where at least one of said 1.sup.st and 2.sup.nd transmit pulsed waves are essentially a plane wave.
10. A method for measurement or imaging of nonlinear interaction scattering according to claim 1, where at least one of said 1.sup.st and 2.sup.nd transmit pulsed waves are a focused wave.
11. A method according to claim 1, where at least a receive beam is scanned in one or both of i) an azimuth direction, and ii) an elevation direction to produce 2D and 3D images of the nonlinear interaction scattering.
12. An apparatus for measurement or imaging of nonlinear interaction scattering between two waves in a material object with nonlinear material parameters that produce wave scattering, comprising a) transmit means arranged to transmit at least one transmit event comprising i) at least one 1.sup.st transmit pulsed wave with a 1.sup.st transmit time and a 1.sup.st transmit center frequency along a 1.sup.st transmit beam with a 1.sup.st transmit direction, and ii) at least one 2.sup.nd transmit pulsed wave with a 2.sup.nd transmit time and a 2.sup.nd transmit center frequency along a 2.sup.nd transmit beam where said 1.sup.st transmit beam crosses said 2.sup.nd transmit beam in the elevation direction at an angle θ between the forward propagation directions of the beams where θ is in the range (20 -340) deg, and where the 1.sup.st and 2.sup.nd transmit beams and 1.sup.st and 2.sup.nd transmit times are arranged so that the pulses from the 1.sup.st and 2.sup.nd pulsed waves overlap in space in an overlap region Z, and b) control means arranged to select one or both of i) the time relation between said 1.sup.st and 2.sup.nd transmit times, and ii) the pulse length of at least one of the 1.sup.st and 2.sup.nd transmit pulses, to control the depth location and dimension of said overlap region Z of nonlinear interaction between said 1.sup.st and 2.sup.nd pulsed waves that produces nonlinear interaction scattering within the object, and c) receive means arranged to receive at least scattered wave components from the overlap region Z with at least one receiver and generating at least one receive signal that includes at least nonlinear interaction scattered signal components that relate to waves that are scattered from the nonlinear interaction between said 1.sup.st and 2.sup.nd pulsed waves in said overlap region, and d) processing means arranged to process said at least one receive signal to extract the nonlinear interaction scattered signal components and to form nonlinear interaction measurement or image signals from said nonlinear interaction region.
13. An apparatus according to claim 12, where said processing means comprises means for temporal frequency filtering of the receive signal where said filtering passes said nonlinear interaction scattered signal components and blocks other temporal frequency components.
14. An apparatus according to claim 12, where a) said transmit means is arranged to transmit at least two transmit events where said 1.sup.st and 2.sup.nd transmit beams and the time lag between said 1.sup.st and 2.sup.nd transmit times are the same for said at least two transmit events, and where b) said transmit means comprises means for varying at least one of polarity, amplitude, phase and frequency of one of said 1.sup.st and 2.sup.nd pulsed waves between said at least two transmit events, including the possibility that at least one of said 1.sup.st and 2.sup.nd pulsed waves has zero amplitude for at least one of said at least two transmit events, and where c) said processing means comprises means for combining the receive signals from at least two transmit events in the process of forming image signals in said overlap region.
15. An apparatus according to claim 14, where said transmit means comprises means to transmit said 1.sup.st pulsed wave with a center frequency less than ⅓ of the center frequency of said 2.sup.nd pulsed wave.
16. An apparatus according to claim 14, where said processing means is arranged for delay correcting at least one of the receive signals from said at least two transmit events before combining the receive signals from said at least two transmit events.
17. An apparatus according to claim 14, where said processing means comprises means that in addition includes temporal frequency filtering of the receive signal where said filtering passes said nonlinear interaction scattered signal components and blocks other temporal frequency components.
18. An apparatus according to claim 1, where said transmit means comprises means to transmit 1.sup.st and 2.sup.nd beams where the angle between the beams θ is any angle in the interval (160 -200) deg
19. An apparatus according to claim 17, where said transmit means comprises means to transmit said 1.sup.st at an angle θ to said 2.sup.nd beam where θ is so much different from 180 deg that one of, i) the 1.sup.st transmitted pulse hits the receive array at an angle with reduced sensitivity of the receive array, and ii) passes outside the receive array.
20. An apparatus according to claim 1, where said transmit means transmits at least one of said 1.sup.st and 2.sup.nd transmit pulsed waves as essentially plane waves.
21. An apparatus according to claim 1, where said transmit means transmits at least one of said 1.sup.st and 2.sup.nd transmit pulsed waves as a focused wave.
22. An apparatus according to claim 1, where said processing means comprises means to average received signals from a plurality of transmit events for the same measurement or image region to reduce noise and improve sensitivity.
23. An apparatus according to claim 1, where said receive means comprises means to scan a receive beam in an azimuth direction to produce 2D images of the nonlinear interaction scattering.
24. An apparatus according to claim 1, where said receive means comprises means to scan a receive beam both in an azimuth and elevation direction to produce 3D images of the nonlinear interaction scattering.
25. An apparatus according to claim 12, where at least one of said 1.sup.st and 2.sup.nd pulsed waves is an elastic compression wave.
26. An apparatus according to claim 12, where at least one of said 1.sup.st and 2.sup.nd pulsed waves is an elastic shear wave.
27. An apparatus according to claim 12, where at least one of said 1.sup.st and 2.sup.nd pulsed waves is an electromagnetic wave.
28. An apparatus according to claim 25, where said receive means is a focused camera.
Description
SUMMARY OF THE DRAWINGS
[0015]
[0016]
[0017]
[0018]
[0019]
[0020]
[0021]
DETAILED DESCRIPTION OF THE PREFERRED EMBODIMENTS OF THE INVENTION
[0022] We will here give examples of embodiments according to the invention. The description does not present any limitations as to the extent of the invention, where the invention is solely defined by the claims appended hereto.
[0023] We use acoustic pressure waves in an object with 2.sup.nd order elasticity as an example for description of the invention. It will however be clear to anyone skilled in the art how this example can be extended to more complex elasticity situations, for example the situation of resonant nonlinear scatterers, the use of acoustic shear waves, acoustic plate waves, acoustic surface waves, sand also electromagnetic waves. Cracks in polymers, polymer composites, or rocks, provide especially strong nonlinear scattering. Methods according to the current invention can for example be used to detect cracks in rocks to assess stability of formations, problems with inflow of water in tunnels, and also assessment of the neighborhood of oil and gas wells. For plates of polymer or polymer composites in constructions in for example airplanes, vessels or windmills, one can for example use the methods of detecting nonlinear interaction scattering according to this invention to detect cracks or other damages in the material both as quality control in manufacturing, and for surveillance of safe operation of constructions. For plates one can conveniently use surface, or plate mode elastic waves, or pressure waves, or a combination of these.
[0024] For the illustrative example of pressure waves, the volume compression δV of a small volume element ΔV by a pressure p, can to the 2.sup.nd order in the pressure be written as δV/ΔV=−∇ψ=(1−β.sub.nκp)κp, where ψ is the particle displacement in the wave, κ is the linear compressibility, and β.sub.n is a nonlinearity parameter. With this nonlinear elasticity we get a wave equation that includes nonlinear forward propagation and scattering phenomena as
where r is the space coordinate vector, t is time, φ(r,t) is the acoustic impulse momentum field defined through ρ(r)u(r,t)=−∇φ(r,t) where u(r,t)=∂ψ(r,t)/∂t is the acoustic particle velocity, ρ(r) is the object mass density, and p(r,t)=∂φ(r,t)/∂t is the acoustic pressure field. c.sub.0(r) is the linear wave propagation velocity for low field amplitudes, β.sub.p(r)=β.sub.n(r)κ(r) is a nonlinear propagation parameter, h.sub.p(r,t) is a convolution kernel that represents absorption of wave energy to heat. σ.sub.l(r) and γ(r) are the relative rapid (on a scale<approximately the wave length) spatial variations of the compressibility and mass density of the object that gives linear scattering parameters, and σ.sub.n(r) is a nonlinear scattering parameter. The left side propagation parameters vary with r on a scale>approximately the wavelength, while the right side scattering parameters vary with r on a scale<approximately the wave length. A similar equation for electromagnetic waves can be formulated that represents similar nonlinear propagation and scattering phenomena for the EM waves.
[0025] The different terms of Eq.(2) have different effects on the wave propagation and scattering: The linear propagation terms (1) guide the linear forward propagation of the incident wave without producing new frequency components. The linear scattering source terms (4) produce local scattering of the forward propagating wave without producing new frequency components in the scattered wave. More detailed analysis shows that the nonlinear propagation term (2) modifies the propagation velocity through a combination of term (1+2) as
where we in the last approximation have used that |2β.sub.p(r)p.sub.1(r,t)|=|x|<<1 which allows the approximation √{square root over (1−2x)}≈1−x. The nonlinear variation of the propagation velocity with the pressure p in Eq.(2) arises from that a high positive pressure makes the material stiffer with a corresponding increase in propagation velocity, while a high negative pressure makes the material softer with a corresponding decrease in propagation velocity. This produces a forward propagation distortion of the wave, well known in nonlinear wave propagation. The propagation time t(r.sub.1,r.sub.2) of a field point at (r.sub.1,t.sub.1) of the wave to (r.sub.2,t.sub.2) is in the geometric ray propagation approximation given as
where Γ(r.sub.1,r.sub.2) is the geometric ray propagation path from r.sub.1 to r.sub.2, p(s) is the wave pressure at the field point as a function of propagation, t.sub.0(r.sub.1,r.sub.2) is the propagation time in the low amplitude linear regime, and τ(r.sub.1,r.sub.2) is the nonlinear modification of the propagation time which we denote the nonlinear propagation delay.
[0026] Hence, for materials with adequately high nonlinearity in the material parameters relative to the wave field amplitude, the nonlinearity affects both the propagation velocity and local scattering of the wave. A slowly varying (close to constant on a scale>˜wave length) of the nonlinear material parameters will provide a nonlinear forward propagation distortion of the incident waves that accumulates/increases in magnitude with propagation distance through term (2) of Eq.(1). A rapid oscillation (on a scale<˜wavelength) of the nonlinear material parameters produces a local nonlinear scattering of the incident waves through term (5) of Eq.(1).
[0027] The nonlinear propagation (2) and scattering (5) phenomena are in the 2.sup.nd order approximation of material parameters are both proportional to 2p{umlaut over (φ)}=2p{dot over (p)}=∂p.sup.2.sub.p.sup.2 /∂t. For a wave that is a sum of two components p=p.sub.1+p.sub.2 as in our example, the nonlinear propagation and scattering are both given by
[0028] A multiplication of two functions in the temporal domain produces a convolution of the functions temporal Fourier transforms (i.e. temporal frequency spectra) in the temporal frequency domain. This convolution introduces frequency components in the product of the functions that are sums and differences of the frequency components of the factors of the multiplication. For the nonlinear self distortion terms, this produces harmonic and sub-harmonic components of the incident frequency bands.
[0029]
[0030] The nonlinear scattering source term (5) in Eq.(1) is a monopole scattering term that fundamentally scatters equally in all directions from sources smaller than a wavelength of the incident waves. Interference between neighboring scatterers and scatterers much larger than the wave length will however produce a direction dependent scattering. In this example the scattered signal is received with the array 102, while in
[0031] In this example both pulsed wave beams 103 and 104 are wide in the azimuth direction,
[0032] To transmit wide beams the array 101 could in principle be composed of a single transducer element, as receive resolution is obtained by the array 102. For simple electrical impedance matching to the transmitters to transmit high amplitudes, it is however convenient that the array is composed of several smaller elements. This also allows electronic focusing of the transmit pulse 103. Focusing of the transmit beams increases the transmitted pressure amplitudes p.sub.1 and p.sub.2, that increases the nonlinear scattering ˜p.sub.1p.sub.2 in a selected depth region, also prefer multi-element arrays for transmit, albeit one can also use lenses, all according to known methods. Focusing of the transmit beams require lateral azimuth scanning of the focused transmit beams for 2D or 3D imaging, according to known methods.
[0033] During a time interval Δt, both waves propagate a distance c Δt.
where θ is defined above and in the Figure. For θ.fwdarw.0 both pulses 103 and 104 get the same propagation direction and ΔT.fwdarw.∞, which implies that the phase between the peak of pulse 104 and the oscillation of 103 is constant along their common propagation direction, i.e. pulse 104 surfs on the pulse 103. The polarity of p(s) in Eq.(3) is then constant, and τ(z) in Eq.(3) represents an accumulative increase in magnitude of the nonlinear propagation delay of pulse 104 with depth, which must be accounted for in the signal processing. For θ=π/2 the pulse 103 propagates at right angle to the pulse direction of 104, and we get ΔT=T.sub.1, and for θ=π the pulse 103 propagates in the opposite direction of the pulse 104, and we get ΔT=T.sub.1/2.
[0034] For θ.sub.1<θ<2π−θ.sub.1 where 0<θ.sub.1<π/2 the pressure p(s) of the manipulation pulse 103 at the location of the sensing pulse 104, p(s) included in the integral for the nonlinear propagation delay τ in Eq.(3), will oscillate in polarity with a limited amplitude in the propagation of the pulses, and so will also τ. A typical value for β.sub.p˜2.Math.10.sup.−9 Pa.sup.−1. For a peak pressure of the manipulation pulse of P=1 MPa the maximal value of r becomes from Eq.(3) for f.sub.1=0.5 MHz, T.sub.1=1/f.sub.1 and ω=2πf.sub.1
where we have chosen θ=(45, 90, 180) deg and T.sub.2=100 ns corresponding to a frequency f.sub.2=1/T.sub.2=10 MHz of the sensing pulse 104. This gives τ.sub.max˜(4.3, 1.3, 0.6)ns which could conveniently be corrected for for low values of θ or high values of P, for maximal suppression of non-interacting terms in the received signal.
[0035] We define two groups of nonlinear distortion terms in the received signal:
[0036] Group A originates from the linear scattering, i.e. term (4) of Eq.(1), of the forward accumulative nonlinear propagation distortion components in the incident wave, i.e. combination of term (1+2) and term (4) in Eq.(1). The self-distortion terms are always positive, and the harmonic distortion of the waves hence increases accumulatively with propagation depth, attenuated by absorption that increases with harmonic frequency, and geometric spread of the waves. For the nonlinear interaction term where the waves cross each other at an angle θ, the nonlinear term of the propagation velocity in Eq.(2) will oscillate with propagation depth due to the oscillations in p(s) in Eq.(3), and with adequately large angle θ between the beams, the forward propagation distortion of this term is oscillatory and may be negligible for strong nonlinear interaction scattering terms.
[0037] Group B originates directly in the local nonlinear scattering of the incident waves, i.e. term (5), and is often be weaker than the Group A for terms where the forward nonlinear accumulation distortion is effective. With an adequately large angle θ between the 1.sup.st and 2.sup.nd incident waves the nonlinear forward distortion is low for the nonlinear interaction term Eqs.(5,6), but not for the self distortion terms, and this allows detection of the nonlinear interaction scattering with the current invention.
[0038] There is also in principle a Group C found as local nonlinear scattering from term (5) of the forward accumulative nonlinear propagation distortion components in the incident wave, i.e. interaction between term (1+2) and term (5) in Eq.(1), but typical nonlinear material parameters are so low that this group is negligible.
[0039]
[0040] We note that the harmonic bands of 201 and 202 are not shown in the Figure. In many situations one can get harmonic bands from self distortion components of the incident bands 201 or 202 that interferes with the nonlinearly interaction scattered bands 203 and 204, either through forward propagation distortion with linear scattering (Group A) or local nonlinear scattering (Group B), reducing the sensitivity to the nonlinear interaction scattering. Group A is generally the strongest, but Group B can also be strong with nonlinear resonant scatterers like ultrasound contrast agent micro-bubbles. One way to improve this situation is to use the method of pulse inversion where one transmits two pulse sets of 1.sup.st and 2.sup.nd pulses, changing the polarity of one of p.sub.1 and p.sub.2 for the 2.sup.nd pulse set. The polarity of the scattered nonlinear interaction term ˜2p.sub.1p.sub.2 will then change polarity for the 2.sup.nd pulse set, while the even (2.sup.nd, 4.sup.th, . . . ) harmonic self-distortion components ˜p.sub.1.sup.2 and p.sub.2.sup.2, for both Group A and Group B scattering, will not change polarity. Hence, subtracting the receive signals from these two transmit events in the method often referred to as pulse inversion, will then enhance the nonlinear interaction scattering term above even harmonic components of the incident bands. The transmitted pulse 103, p.sub.1, will in the current example arrive at the receiving transducer 102 at the same time as the nonlinear interaction scattered signal. Changing the polarity of p.sub.2 (104) in this pulse inversion process, will then suppress potential received components of p.sub.1 in the received signal at 102. Linearly scattered components from the pulse p.sub.2, which has changed polarity, at 102 will be enhanced in this process, and can be suppressed by filtering in the time domain.
[0041]
[0042] With a distance L between transducer array 101 and 102 the manipulation wave (1.sup.st wave) propagates a distance L-z to the interaction depth z, while the sensing wave (2.sup.nd wave) propagates a distance 2z back and forth to the interaction depth z. The frequency f.sub.2 for the 2.sup.nd wave p.sub.2 (sensing wave) is chosen as high as possible to obtain adequate signal and best possible resolution for the depth range. To further improve sensitivity for the nonlinear interaction term ˜2p.sub.1(r,t)p.sub.2(r,t) for L−z large, it is useful to select the frequency f.sub.1 of the 1.sup.st wave p.sub.1 (manipulation wave) as low as possible for low absorption, but adequately high to get an adequately collimated pulse 103, p.sub.1. We call this the low frequency (LF) pulse. The high frequency (HF) f.sub.2 is selected high to get adequate spatial resolution for the given imaging depth into the object, for example with the frequency ratio f.sub.1:f.sub.2˜1:3-1:30. In particularly preferred embodiments the ratio is in the order of ˜1:10. For ultrasound imaging one could for example in one application choose f.sub.2˜10 MHz to image down to 40 mm with f.sub.1˜1 MHz, or in another application choose f.sub.2˜3.5 MHz to image down to 150 mm with f.sub.1 ˜0.3 MHz, i.e. a frequency ratio of about 1:10. Similar examples are found for scattering of EM waves. For imaging of contrast agent micro-bubbles at frequencies f.sub.2 well above the bubble resonance frequency, one would preferably choose f.sub.1 below or around the resonance frequency, as the LF pulse 103 would then manipulate the bubble diameter.
[0043] In
[0044]
[0045]
[0046] The example embodiment in
[0047] To get strong nonlinear scattering one wants as high amplitude of the 1.sup.st transmitted pulse as possible, and this limits the pulse length to avoid over-heating of the transducer array and the tissue. We should note that with this arrangement of the arrays, the 1.sup.st transmit pulse 103 will hit the receiver array 102 at the same time as the nonlinearly scattered signal components from Z which are much lower in amplitude. This can cause difficulties in adequate suppression of the receive components of the pulse 103 to show the nonlinear interaction scattering components with high sensitivity, especially with low difference between the frequency f.sub.1 of pulse 103 and the nonlinear interaction components to be detected. The frequency selections described in
[0048] When the manipulation pulse p.sub.1 has much lower frequency than the imaging pulse p.sub.2, as exemplified in
[0049] With this method one hence gets regions of strong nonlinear interaction scattering with depth distance λ.sub.1/4 within the whole overlap region, indicated as the lines 507 within the overlap region 500 in
[0050] The transmitted pulse amplitudes can be increased to increase the nonlinear interaction scattering by using overlapping, focused transmit pulses 103 and 104, and scanning said focused beams in the azimuth direction for 2D imaging, and both azimuth and elevation direction for 3D imaging, with adapted receive beam scanning, according to known methods. Elevation scanning for 3D imaging can be done by mechanical motion of the array structure as illustrated by the arrows 112 in
[0051] A block diagram of an instrument according to the invention is shown in
[0052] To provide maximal sensitivity to the frequency components in the nonlinear interaction scattered signal the scattered signal can also be picked up by a third array, for example illustrated as 607 in
[0053] When the object can be completely surrounded by arrays, for example as with breast imaging, one can conveniently use a ring array known in the art for transmission of pulsed beams 103 and 104 where the direction of the beams are freely selectable by selecting the elements of the ring array used for the transmission. The ring array gives large flexibility for choosing the receive array aperture. This selection is convenient to provide spatial compounding of images obtained by different directions of the beams, known in the art. For transmission of pulses 103 and 104 that are widely separated in frequency as in
[0054] In
[0055] We have used ultrasound imaging as an example, but similar geometrical arrangements of transmitters and receivers can according to the invention also be used with EM waves. For EM imaging with frequencies in the GHz and THz range, the transmit means and receive means can be strip antennas or maser/laser diodes, and arrays of elements of these. For EM imaging in the infrared-optical frequency range, simple solutions for the transmit means are arrays of laser diodes, or mechanically direction steered laser diodes. Simple solutions for the receive detector means can be light sensing diodes/transistors or focused camera systems (e.g. a CCD camera) that provides real time imaging of the scattered signal from the whole interaction region. To further increase the sensitivity to the nonlinear interaction scattered signal, one can conveniently average the receive signal or image signal from many transmit events for each individual interaction region, according to known methods.
[0056] Thus, while there have been shown and described and pointed out fundamental novel features of the invention as applied to preferred embodiments thereof, it will be understood that various omissions and substitutions and changes in the form and details of the devices illustrated, and in their operation, may be made by those skilled in the art without departing from the spirit of the invention.
[0057] It is also expressly intended that all combinations of those elements and/or method steps which perform substantially the same function in substantially the same way to achieve the same results are within the scope of the invention. Moreover, it should be recognized that structures and/or elements and/or method steps shown and/or described in connection with any disclosed form or embodiment of the invention may be incorporated in any other disclosed or described or suggested form or embodiment as a general matter of design choice. It is the intention, therefore, to be limited only as indicated by the scope of the claims appended hereto.