COMPOSITION COMPRISING HYALURONIC ACID AND ROC® AND ITS USE
20170333511 · 2017-11-23
Inventors
Cpc classification
A61Q17/04
HUMAN NECESSITIES
A61K9/0095
HUMAN NECESSITIES
A61P19/06
HUMAN NECESSITIES
A61K31/192
HUMAN NECESSITIES
A61K9/0053
HUMAN NECESSITIES
A61K8/368
HUMAN NECESSITIES
A61K2300/00
HUMAN NECESSITIES
A61K2300/00
HUMAN NECESSITIES
A61K8/375
HUMAN NECESSITIES
A61K31/7048
HUMAN NECESSITIES
A61K31/7048
HUMAN NECESSITIES
A61K8/735
HUMAN NECESSITIES
A61K31/192
HUMAN NECESSITIES
A61P1/00
HUMAN NECESSITIES
International classification
A61K9/00
HUMAN NECESSITIES
Abstract
A composition containing hyaluronic acid and a Vitamin C containing extract obtained from pigmented varieties of blood oranges and its use is described.
Claims
1. A pharmaceutical or cosmetic composition comprising hyaluronic acid and ROC®.
2. The composition according claim 1, wherein said composition comprises preservatives.
3. The composition according claim 2, wherein said preservatives are selected from the group consisting of potassium sorbate, and sodium benzoate.
4. The composition according to claim 1, wherein said hyaluronic acid has a molecular weight higher than 500000 Da.
5. The composition according to claim 1, wherein said hyaluronic acid has a molecular weight of 1000000 Da.
6. The composition according to claim 1, wherein said composition comprises: hyaluronic acid in the range of 50-55%; ROC in the range of 35-45%; preservatives in the range of 0-12%.
7. The composition according to claim 6, wherein said composition comprises: hyaluronic acid at 52.00%; ROC® at 38.40%; preservatives at 9.60%.
8. The composition according to claim 1 wherein said composition is liquid and for oral use.
9. (canceled)
10. (canceled)
Description
Example 1
[0071] 1. Hyaluronic acid with a high molecular weight (9 mg/ml) and ROC® (6.66 mg/ml) were mixed in an aqueous solution and the water was heated at 95° C. for 30 minutes. [0072] 2. The resultant solution from 1. was cooled down to 65° C. and, once it was reached the said temperature, the preservatives potassium sorbate (1 mg/ml-0.10%) and sodium benzoate (0.6 mg/ml-0.07%) were added. [0073] 3. The resultant solution from 2. was subsequently cooled down to 20° C. [0074] 4. Quality checks were made on the resultant solution from 3. [0075] The final formulation is a liquid composition which comprises (% expressed in weight/final weight): [0076] Water: 98.28% [0077] Hyaluronic acid: (9 mg/ml): 0.90% [0078] ROC (6.66 mg/ml): 0.66% [0079] Preservatives: 0.16%