Throat solution for treatment of cold, flu and sore throat

Abstract

A composition of isopropyl or ethyl alcohol, Cetylpyridinium Chloride and essential oils that enable the composition to have a prolonged antimicrobial effect by reducing the normal rate of alcohol dehydration, reducing toxicity and increasing duration of efficacy with proper application to oral cavity, oropharynx and directly pharyngeal tonsils.

Claims

1. The antimicrobial composition of mixed component for topical application in the throat, comprising: an ethyl or isopropyl alcohol component between 15%-35% by weight and 50%-70% by volume; a composition of various base and essential oils between 60%-80% by weight; Cetylprydnium Chloride no greater than 10% by weight; a proprietary flavor additive no greater than 5% by weight for supplementing, neutralizing, activating and reducing the dehydrating effect of said alcohol thus enabling the necessary contact time effectively kill the germs that cause sore throat without mucosal toxicity or irritation.

2. The peppermint, spearmint, menthol or like essential oil no greater than 4% by weight, in combination with solution, neutralizes the undesirable affect from alcohol aroma, temporarily reduces associated pain from a throat infection, temporarily improves sensation of breathing and provides temporary flavor enhancement.

3. The composition is created with a high viscosity and is applied with direct high velocity or friction in order to penetrate affected or targeted tissues resulting in a greater antimicrobial effect.

4. The said composition according to claim 1, wherein said Cetylprydnium Chloride can be added to increase the antimicrobial effect.

5. The said composition according to claim 1, wherein said essential oils are added for increasing natural antimicrobial effect.

6. The said composition according to claim 3, a proprietary emulsification process may be utilized as an alternative to manual mixing.

7. The said composition according to claim 1, wherein said base oils between 60% and 80% by weight such as sunflower oil, safflower oil, peanut oil, olive oil, coconut oil, soybean oil, avocado oil, corn oil, almond oil, canola oil, grape oil component can be utilized individually or in a combination and have shown to have natural antiseptic, absorption and tissue regeneration properties.

8. The said composition according to claim 1, wherein said proprietary variant viscosity flavor additives such as strawberry or alternative, cherry, grape, lemon, lime, orange, bubble gum, berry berry, coffee, vanilla, chocolate, mint, blueberry not exceeding 8% by weight is utilized, which enhances or aids in neutralizing the alcohol affect or aroma.

9. The said composition according to claim 1, wherein said essential lemon oil or alternate lemon balm no greater than 4% by volume, may be added to enhance antimicrobial efficacy, deliver nutrients to tissues and helps to neutralize the after taste of alcohol and oils.

10. The said composition according to claim 1, wherein said essential aloe vera oil extract no greater than 4% by volume, is added to enhance tissue healing and regeneration.

11. The said composition according to claim 1, wherein the said antimicrobial solution has shown to reduce or eliminate the infection in the throat better than other solutions including, mouthwash, saltwater solution, over the counter throat sprays and peroxide base products.

12. The said composition according to claim 1, wherein the said antimicrobial solution has shown to reduce or eliminate germs that cause bad breathe, the oil base helps reduce dehydration of active ingredients on the tongue and pharyngeal mucosa.

13. The said composition according to claim 1, wherein the said composition has shown to kill common respiratory bacteria in time kill studies (99.9% effective). Alcohol products for the throat have never presented this activity because of rapid evaporation or dilution with saliva.

14. The said composition according to claim 1, wherein the said composition has shown to kill respiratory virus in time kill studies 98.33-99.9%. Alcohol products for the throat have never demonstrated this type of efficacy for virus because of rapid evaporation or dilution.

15. The said composition according to claim 1, wherein the said composition even in the highest dosage formulary has shown to not produce and dermal irritation or dermal toxicity to mucosal tissues. The alcohol is diluted by up to thirty percent with water and then that mixture is diluted by up to 85% with oil. No adverse side effects have ever been reported during clinical testing.

Description

SUMMARY OF THE INVENTION

[0010] The present invention relates to a throat (mucosal) disinfectant topically applied or by spray that effectively destroys various pathogenic organisms that cause sore throat. The solution coats the throat and specifically the pharyngeal tonsil region and does not rapidly evaporate thus maintaining antimicrobial efficacy for a duration long enough to reduce or even eliminate active infection and the symptoms associated.

TABLE-US-00001 Time Kill Studies Rhinovirus (Common Cold) 98.33% Coronavirus (SARS) 99.99% Influenza A (Bird Flu) 99.99% Adenovirus 99.99% Staphylococcus Aureus 99.99% Streptococcus Pneumoniae 99.99% Streptococcus Pyogenes 99.99% Hemophilius Influenzae 99.99%

[0011] SKIN IRRITATION STUDY: Under the conditions of the study, irritation was observed on the skin of the rabbits. The primary irritation index was calculated to be 1.08. The test article would not be considered a primary irritant to the skin since the empirical score was less than 5.00. It has been determined by the FDA that score results below 5.00 on rabbits is very safe for human skin.

[0012] DERMAL TOXICITY STUDY: Under the conditions of the study, there was no mortality or significant evidence of toxicity observed in the rabbits. The test article would not be considered toxic at a dose of 2 g/kg by the dermal route in the rabbits.

Comparison To Common use Mouthwash Products:

[0013] Due to the extensive background in research and development of Dr. Baugh, Custom Biologicals is the industry leader in selecting and adapting natural microorganisms for a multitude of industrial, agricultural, and domestic applications. Additionally, CBI has the strength of the unique proprietary production methods developed by Dr. Baugh for bacterial products.

[0014] The antimicrobial solution did not inactivate the bacillus cereus spore, however it was very effective for killing the vegetative cells. There are many mouthwash type products that will kill vegetative cells, but not at the speed of your solution.