COMPOSITION, CONTAINING HIGH-HARDNESS MINERAL WATER PREPARED FROM SALTY UNDERGROUND WATER OR DEEP-SEA WATER, FOR PREVENTING OR ALLEVIATING DECREASE IN BLOOD PRESSURE OR SYMPTOMS RELATED THERETO

Abstract

The present invention relates to a composition, containing, as an active ingredient, high-hardness mineral water prepared from salty underground water or deep-sea water, for preventing or alleviating a decrease in blood pressure or symptoms related thereto. According to the present invention, the high-hardness mineral water prepared from salty underground water or deep-sea water, especially, prevents a rapid decrease in blood pressure or mitigates the degree of decrease in blood pressure, during or after exercise, and thus can be used to prevent or alleviate symptoms related to a rapid decrease in blood pressure during or after exercise.

Claims

1-8. (canceled)

9. A method for preventing or alleviating a decrease in blood pressure comprising a step of administering a composition to a subject in need thereof, wherein the composition containing mineral water having a hardness value of 100-2000 prepared from salty underground water or deep sea water as an active ingredient.

10. A method for preventing or alleviating blood pressure decrease-associated symptoms caused by a decrease in blood pressure comprising a step of administering a composition to a subject in need thereof, wherein the composition containing mineral water having a hardness value of 100-2000 prepared from salty underground water or deep sea water as an active ingredient, wherein the blood pressure decrease-associated symptoms being selected from the group consisting of dizziness, headache, fainting, wobbling, nausea, numbness, systemic weakness, temporary visual and hearing impairment, nervous breakdown, constipation, insomnia, slow pulse, pale skin, shock and arrhythmia.

11. The method of claim 9, wherein the mineral water contains 15-500 mg/l magnesium, 5-170 mg/l calcium, and 4.5-150 mg/l potassium.

12. The method of claim 9, wherein the mineral water has a hardness value of 100-1200.

13. The method of claim 9, wherein the mineral water contains 15-300 mg/l magnesium, 5-102 mg/l calcium, and 4.5-90 mg/l potassium.

14. The method of claim 9, wherein the decrease in blood pressure is a decrease in blood pressure during or after exercise.

15. The method of claim 9, wherein the composition is drinking water, tea, a sports drink, an isotonic drink or an energy drink.

16. The method of claim 9, wherein the mineral water is prepared to have a hardness of 100-2000 by mixing desalted water, which is obtained by performing a desalting treatment on salty underground water or deep sea water, with: (i) a mineral concentrate obtained by separating calcium salt crystals and salt from concentrated water obtained by performing a desalting treatment on salty underground water or deep sea water; and (ii) calcium salts obtained by removing, from the calcium salt crystals separated from the concentrated water, salt and calcium carbonate attached to the calcium salt crystals, and wherein the mineral concentrate is obtained by filtering through a filter having a physical adsorbent, re-filtering the filtered mineral concentrate through a filter having a physical adsorbent, and then filtering the re-filtered mineral concentrate through a hollow fiber membrane filter having a plurality of pores.

18. The method of claim 10, wherein the mineral water contains 15-500 mg/l magnesium, 5-170 mg/l calcium, and 4.5-150 mg/l potassium.

19. The method of claim 10, wherein the mineral water has a hardness value of 100-1200.

20. The method of claim 10, wherein the mineral water contains 15-300 mg/l magnesium, 5-102 mg/l calcium, and 4.5-90 mg/l potassium.

21. The method of claim 10, wherein the decrease in blood pressure is a decrease in blood pressure during or after exercise.

22. The method of claim 10, wherein the composition is drinking water, tea, a sports drink, an isotonic drink or an energy drink.

23. The method of claim 10, wherein the mineral water is prepared to have a hardness of 100-2000 by mixing desalted water, which is obtained by performing a desalting treatment on salty underground water or deep sea water, with: (i) a mineral concentrate obtained by separating calcium salt crystals and salt from concentrated water obtained by performing a desalting treatment on salty underground water or deep sea water; and (ii) calcium salts obtained by removing, from the calcium salt crystals separated from the concentrated water, salt and calcium carbonate attached to the calcium salt crystals, and wherein the mineral concentrate is obtained by filtering through a filter having a physical adsorbent, re-filtering the filtered mineral concentrate through a filter having a physical adsorbent, and then filtering the re-filtered mineral concentrate through a hollow fiber membrane filter having a plurality of pores.

Description

BRIEF DESCRIPTION OF THE DRAWINGS

[0069] FIG. 1 shows a change in systolic blood pressure in an active group and a control group.

[0070] FIG. 2 shows a change in diastolic blood pressure in an active group and a control group.

MODE FOR CARRYING OUT THE INVENTION

[0071] Hereinafter, the present invention will be described in detail with reference to examples. These examples are only for illustrating the present invention more specifically, and it will be apparent to those skilled in the art that the scope of the present invention is not limited by these examples.

EXAMPLE

Verification of Effect of Preventing Blood Pressure Decrease by Intake of High-Hardness Mineral Water

Methods

[0072] It was examined whether a sudden decrease in blood pressure during or after exercise was prevented by the intake of high-hardness mineral water at the time of a 100 km ultramarathon. Specific experimental methods were as follows. Of the participants participating in the 100 km ultramarathon, 23 subjects in a control group and 30 subjects in an experimental group were selected in advance. The experimental group and the control group were distinguished from each other by wearing LED bands (Belt ON LED bands, Hyeonwoo International Inc.) with different colors on their wrists. General purified water (hardness: 30) as drinking water was supplied to the control group and mineral water (Aribio Co., Ltd.) having a hardness of 700 was supplied to the experimental group. Here, 30 runners in the experimental group supplemented mineral water of hardness 700 in each water bottle or water bag at every water supply support section.

[0073] The present study was designed with a randomized block design. As for blocking variables, the systolic blood pressure was set within an error range, leading to no difference between groups. The systolic and diastolic blood pressures were measured using a mercury blood pressure meter (Spirit, Chinkou Medical Instrument, Taiwan) prior to departure and at 50 km and 100 km (total three times). The water supply support points were a total of six sites including the starting point, and mineral water with 700 hardness and general water (hardness 30) were supplied to all of the subjects. For verification of the difference in blood pressure change by section (0 km, 50 km, 100 km) between the experimental group and the control group, the descriptive statistics of the collected data were calculated using SPSS 16.0 for Windows (Chicago, Ill., USA) and then, the interaction effect was verified through the two-way mixed model multivariate validation [2 (groups; experimental group, control group)×3 (repetition; 0 km, 50 km, 100 km) two mixed design ANOVA]. Comparison verification was conducted to verify the difference in change between time periods. The significance level was set to α=0.05.

Results

[0074] As shown in FIG. 1, there was a significant interaction effect according to the exercise distance (0 km, 50 km, 100 km) in the systolic blood pressure between the experimental group and the control group (F=3.48, p=0.039). At the final 100 km, the experimental group consuming high-hardness mineral water showed a normal blood pressure range, but the control group showed a sharp decrease (p=0.039). As shown in FIG. 2, the diastolic blood pressure was maintained at the normal blood pressure level in the experimental group, and the diastolic blood pressure of the control group was lower than that of the experimental group at the final 100 km, and the width of the decrease was also larger (p=0.13; FIG. 2).

[0075] A rapid decrease in blood pressure during exercise, particularly at the time of exercises requiring much physical exertion, such as a marathon and an ultramarathon, is extremely dangerous, and in severe cases, it causes heart failure, leading to death. The above results show that such a rapid decrease in blood pressure can be prevented through the intake of high-hardness of mineral water.

REFERENCES (INCORPORATED HEREIN BY REFERENCE)

[0076] 1. Chen, Chao-Tin and Bonham (2010). Postexercise hypotension: central mechanisms. Exercise and Sports Science Reviews, 38(3), 122-127.

[0077] 2. Holtzhausen, Lucy-May and Noakes, T. D. (1995). The prevalence and significance of post-exercise (postural) hypotension in ultramarathon runners. Medicine and Science in Sports and Exercise, 27(12), 1595-1601.

[0078] 3. MacDonald, J. R. (2002). Potential causes, mechanisms, and implications of post exercise hypotension. Journal of Human Hypertension, 16, 225-236.

[0079] Although the present invention has been described in detail with reference to the specific features, it will be apparent to those skilled in the art that this description is only for a preferred embodiment and does not limit the scope of the present invention. Thus, the substantial scope of the present invention will be defined by the appended claims and equivalents thereof.