2-AMINOETHANOL DIHYDROGEN PHOSPHATE-BASED DIETARY SUPPLEMENT AND SYNTHESIS PROCESS THEREOF

20170296560 · 2017-10-19

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Inventors

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Abstract

This invention discloses a process for creating an amino acid-based vitamin and mineral dietary supplement and muscle builder having therapeutic activities such as an antioxidant and a metabolic regulator, a regulator of possible cell dysfunctions, an adjuvant of human vitality and well-being and reduction of pain caused by different diseases wherein 2-aminoetanol dihydrogen phosphate is synthesized from phosphorus pentoxide and/or phosphoric acid and/or orthophosphoric acid reacted as monoethanolamine and/or diethanolamine and/or triethanolamine. These are reacted under optimal temperature conditions (−10 to +35° C.) at the specific molar ratios for each reagent used.

Claims

1. 2-AMINOETHANOL DIHYDROGEN PHOSPHATE-BASED DIETARY SUPPLEMENT AND SYNTHESIS PROCESS THEREOF wherein the compound is synthesized from phosphorus pentoxide and/or phosphoric acid and/or orthophosphoric acid reacted as monoethanolamine and/or diethanolamine and/or triethanolamine, comprising: a) reacting them under constant shaking and an inert argon atmosphere or vacuum or nitrogen or other inert gas bubbled inside the solution with the temperature of its ingredients being between −10° C. and 35° C. and the variable values of phosphorus pentoxide and/or phosphoric acid and/or orthophosphoric acid between 0.001 mol and 20 mol, wherein the values between 0.001 mol and 20 mol are used for the basic reagents (monoethanolamine, diethanolamine, and triethanolamine); b) after homogenization, the solution from the previous step is crystallized under some organic solvents such as ethanol, methanol, acetone, dimethyl sulfoxide, dimethylformamide, isopropyl alcohol, propyl alcohol, butyl alcohol, among other alcohols such as xylitol, sorbitol, glycerol, and starch at the minimum molar ratios varying from 0.01 mol to 20 mol of each solvent for each 0.001-25 mol of the homogenized solution wherein the time needed for crystal formation varies from one hour to six weeks, its final yield increasing over time; c) after this step, the solution is filtered and dried under dry air and at a temperature between 20° C. and 120° C.; d) after this step, the carbonates and sulfates of minerals of interest such as calcium, zinc, magnesium, copper, strontium, boron, molybdenum, iron, chromium, iodine, manganese, and selenium in the proportions varying from 0.001 to 1,000 mg are added; e) After this previous step is finished, the solution is dried again at temperatures between 20° C. and 150° C.

2. 2-AMINOETHANOL DIHYDROGEN PHOSPHATE-BASED DIETARY SUPPLEMENT according to claim 1 wherein, after the compound obtained in accordance with claim 1 has been completely dried, other vitamin compounds in the following minimum or maximum proportions: B-complex vitamin (0.001 to 5 grams), vitamin A (200 to 50.000 IU), vitamin E (0.01 to 50 mg), and vitamin K2 (0.01 to 40 mg) are added to it for each gram of the obtained compound.

3. DIETARY SUPPLEMENT according to claim 2 wherein such amino acids of interest as histidine, isoleucina, leucine, lysine, methionine, phenylalanine, threonine, tryptophan, valine, alanine, arginine, aspartic acid, cysteine, glutamic acid, glutamine, ornithine, taurine, proline, serine, and tyrosine in the specific proportions varying from 0.1 mg to 500 mg of each of the compounds specified are also added.

Description

DETAILED DESCRIPTION OF THE INVENTION

[0007] The invention proposed herein is characterized by the description of different steps necessary for implementing the application in question such that it can be fully reproduced by adequate techniques, allowing the full characterization of the functionality of the process claimed herein.

[0008] The disclosure is based on different steps described herein that express the best and preferred manner of carrying out the process idealized herein, clarifying the aspects that may be implied in order to clearly determine the scope of protection claimed herein.

[0009] Said steps may vary insofar as they do not depart from the spirit and scope of the invention.

[0010] Therefore, the products may be created as follows:

[0011] In accordance with the present invention, the compound is synthesized from phosphorus pentoxide and/or phosphoric acid and/or orthophosphoric acid reacted as monoethanolamine and/or diethanolamine and/or triethanolamine. These are reacted under optimal temperature conditions (−10 to +35° C.) at the specific molar ratios for each reagent used and described above.

[0012] The synthetic pathway described herein uses the reagents disclosed above. In this reaction, they are reacted under constant shaking and an inert argon atmosphere or vacuum or nitrogen or other inert gas bubbled inside the solution with the temperature of its ingredients being between −10° C. and 35° C. and the variable values of phosphorus pentoxide and/or phosphoric acid and/or orthophosphoric acid between 0.001 mol and 20 mol. The values between 0.001 mol and 20 mol are used for the basic reagents (monoethanolamine, diethanolamine, and triethanolamine). After the reaction step, the resulting solution is heated up to the threshold temperature of 230° C. and homogenized with water at the molar ratios between 0.001 mol and 20 mol of water. After homogenization, said solution is crystallized under some organic solvents such as ethanol, methanol, acetone, dimethyl sulfoxide, dimethylformamide, isopropyl alcohol, propyl alcohol, butyl alcohol, among other alcohols such as xylitol, sorbitol, glycerol, and starch at the molar ratios between 0.01 mol and 20 mol of each solvent for each 0.001-25 mol of the homogenized solution. The time needed for crystal formation varies from one hour to six weeks, its final yield increasing over time. After this step, the solution is filtered and dried under dry air at a temperature between 20° C. and 120° C. After this step, the carbonates and sulfates of minerals of interest such as calcium, zinc, magnesium, copper, strontium, boron, molybdenum, iron, chromium, iodine, manganese, and selenium in the proportions that vary from 0.001 to 1,000 mg are added. After this step is finished, the solution is dried again at temperatures between 20° C. and 150° C. After it is completely dried, other vitamin compounds in the following minimum or maximum proportions: B-complex vitamin (0.001 to 5 grams), vitamin A (200 to 50.000 IU), vitamin E (0.01 to 50 mg), and vitamin K2 (0.01 to 40 mg) are added to it for each gram of the obtained compound. Such amino acids of interest as histidine, isoleucina, leucine, lysine, methionine, phenylalanine, threonine, tryptophan, valine, alanine, arginine, aspartic acid, cysteine, glutamic acid, glutamine, ornithine, taurine, proline, serine, and tyrosine in the specific proportions varying from 0.1 mg to 500 mg of each of the compounds specified are also added. Finally, said solution is ground, homogenized, and prepared in different delivery forms for better application in humans.