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| Patent | Abstract |
|---|---|
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Antibiotic produced by Bacillus subtilis ATCC 55422 capable of inhibiting bacteria
Patent number: 5364623 Assignee: Bristol Myers Squibb Company (Princeton, NJ) Inventors: Pramathesh S. Patel (Ringoes, NJ), Friedrich Mayerl (Norwalk, CT), Edward Meyers (East Brunswick, NJ) |
The invention is drawn to an antibiotic produced by Bacillus subtilis ATCC 55422 having a nominal molecular weight of 580 and the empirical formula C.sub.35 H.sub.48 O.sub.7, or a salt thereof. The antibiotic is useful in inhibiting the growth of bacteria, including Escherichia, Klebsiella, Proteus, Serratia, Bacillus and Staphylococcus. |
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Manumycin compounds
Patent number: 5444087 Assignee: Bristol Myers Squibb Company (Princeton, NJ) Inventors: Pramathesh S. Patel (Ringoes, NJ), Yue-Zhong Shu (Cheshire, CT) |
Manumycin C, Manumycin D and Manumycin E, obtainable by cultivation of a strain of Streptomyces sp. A.T.C.C. No. 55484, oxidized derivatives thereof and salts and prodrugs of these compounds. The novel compounds have antibacterial and antitumor activity. |