A material non-adhesive to a biological substance containing: a polymer compound (A) which includes a repeating unit derived from a sulfobetaine monomer represented by Formula (I) or (II).

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In the formulae, R.sup.1 represents a methyl group, an ethyl group, an n-propyl group, or an isopropyl group, a plurality of R.sup.1's may be the same as or different from each other. R.sup.2 represents a hydrogen atom or a methyl group. n represents an integer of 2 to 4. L represents a linear or branched alkylene group having 3 or 4 carbon atoms.

A medical device includes a base layer, and a lubrication layer supported on at least a part of the base layer, wherein the lubrication layer contains a block copolymer (A) composed of a first constituting unit derived from a reactive monomer that has an epoxy group and a second constituting unit derived from at least one hydrophilic monomer selected from the group consisting of acrylamide and an acrylamide derivative, and a polymer (B) composed of a constituting unit derived from at least one hydrophilic monomer selected from the group consisting of acrylamide and an acrylamide derivative, wherein the block copolymer (A) is contained in a proportion of 20 to 80% by weight relative to the total weight of the block copolymer (A) and the polymer (B), and wherein the block copolymer (A) is crosslinked or polymerized to form a mesh structure.

Hygienic Hydrophilic coatings, hydrophilic coating formulations and wetting fluids that include an anti-infective agent.

Deflectable catheters, hemostasis valves, and materials for the same are disclosed. The deflectable catheters and hemostasis valves can be made at least partially, if not entirely, from a fluoroelastomer and ePTFE combination. A deflectable region of the catheters can be articulated to form simple and/or complex curves.

Deflectable catheters, hemostasis valves, and materials for the same are disclosed. The deflectable catheters and hemostasis valves can be made at least partially, if not entirely, from a fluoroelastomer and ePTFE combination. A deflectable region of the catheters can be articulated to form simple and/or complex curves.

The present invention disclosed a process to coat the surface of flexible polymeric implant with biocompatible polymer such that the coating does not crack when the implant is subjected to mechanical forces such as tension, torsion or bending while retaining the inherent properties of the coated polymer.

In some examples, a catheter includes a structural support member including bamboo. For example, a catheter may include a bamboo coil and/or a bamboo braided member positioned between an inner liner and an outer jacket. The structural support member comprising bamboo may be configured to be biodegradable.

Lubricious hydrophilic coatings and methods of making the same.

The invention relates to a method for obtaining a bacterial extract produced by the bacteria Kocuria marina sp., which prevents biofilm formation, to said extract, and to the use thereof for incorporation into natural or synthetic polymers intended to form structures with active surfaces for preventing microbial biofilm formation, whether for biomedical uses, including clinical uses, industrial uses, or even domestic uses.

The present invention relates to inhibiting or preventing infection and protecting against patency complications after a blood catheter has been in a patient comprising administering to the device a pharmaceutically effective amount of a composition comprising:

(A) at least one taurinamide derivative,

(B) at least one compound selected from the group consisting of biologically acceptable acids and biologically acceptable salts thereof; and

(C) heparin at a low concentration.