An aromatherapy diffuser includes a diffuser body and a diffusion device. The diffuser body has an oil storage cavity for storing a predetermined amount of essential oil. The diffusion device is supported in the diffuser body, and includes an ultrasonic vibrator arranged to generate ultrasonic vibrations, in such a manner that when the diffusion body is partially immersed in the water stored in the container, the essential oil is released to the water from the oil storage cavity while the ultrasonic vibrator is arranged to cause ultrasonic vibrations in the water so as to agitate the water molecules for releasing negatively charged mist and essential oil into ambient air.

An electronic device includes a mouthpiece, a bladder, and a mesh assembly having a mesh material and a piezoelectric material. The mesh material is in contact with a liquid of the bladder. The mouthpiece, the bladder, and the mesh assembly are located in-line along a longitudinal axis of the device between opposite longitudinal ends of the device, with the mesh assembly extending between and separating the mouthpiece and the bladder. A liquid-filled cartridge also is disclosed for use with an electronic device for delivery of a substance into a body through respiration includes a liquid container; and a liquid contained within the container for aerosolizing and inhaling by a person using the electronic device. The liquid includes a plurality of nanoparticles in a nanoemulsion, the nanoparticles including the encapsulation of the substance to be delivered into the body through respiration. The nanoemulsion preferably is produced using a microfluidizing machine.

Pre-connected analyte sensors are provided. A pre-connected analyte sensor includes a sensor carrier attached to an analyte sensor. The sensor carrier includes a substrate configured for mechanical coupling of the sensor to testing, calibration, or wearable equipment. The sensor carrier also includes conductive contacts for electrically coupling sensor electrodes to the testing, calibration, or wearable equipment.

Pre-connected analyte sensors are provided. A pre-connected analyte sensor includes a sensor carrier attached to an analyte sensor. The sensor carrier includes a substrate configured for mechanical coupling of the sensor to testing, calibration, or wearable equipment. The sensor carrier also includes conductive contacts for electrically coupling sensor electrodes to the testing, calibration, or wearable equipment.

The present invention relates to the use of 5-amino-2,3-dihydro-1,4-phthalazinedione or its pharmaceutically acceptable N salts in the inhalatory treatment of inflammatory pulmonary diseases. The invention in particular relates to the use of 5-amino-2,3-dihydro-1,4-phthalazinedione sodium salt for said purposes. Advantageous features of an aerosol containing 5-amino-2,3-dihydro-1,4-phthalazinedione or its pharmaceutically acceptable salts and a method for producing said aerosol are disclosed. The present invention further relates to a kit for inhalatory treatment of inflammatory pulmonary diseases.

Disclosed is a portable inhaler, having a rotary actuation mechanism, and comprising a follower component (104), a rotary loading device (106) and a button (112). The rotary loading device comprises a cam component (108) engaged with a cage component (110), to allow a predetermined limited rotational relative movement therebetween. The button is translatable between a central position and an extended position, and can be engaged by the cam component upon rotary movement of the rotary actuation mechanism to its primed position to translate the button to its extended position, and the button can engage the cam component to effect rotary movement of the rotary actuation mechanism to its actuated position as the button translates to its central position thereby releasing the follower component.

A method of analyzing a spray generated by a spray device for spraying pharmaceutical fluid, including providing a spray head of a spray device for spraying pharmaceutical fluid, the spray head including a spray orifice; causing a test fluid to pass through the spray head towards the spray orifice, the test fluid being air at a temperature that is different from ambient temperature; displaying, by strioscopy, the flow of test fluid leaving the spray orifice; and analyzing the display of the test-fluid flow so as to determine whether or not the test-fluid spray coming from the spray head complies with predetermined specifications. The cycle time for analyzing one spray head is less than 1.5 seconds, advantageously less than 1 second.

A method of analyzing a spray generated by a spray device for spraying pharmaceutical fluid, including providing a spray head of a spray device for spraying pharmaceutical fluid, the spray head including a spray orifice; causing a test fluid to pass through the spray head towards the spray orifice, the test fluid being air at a temperature that is different from ambient temperature; displaying, by strioscopy, the flow of test fluid leaving the spray orifice; and analyzing the display of the test-fluid flow so as to determine whether or not the test-fluid spray coming from the spray head complies with predetermined specifications. The cycle time for analyzing one spray head is less than 1.5 seconds, advantageously less than 1 second.

An electronic device for producing an aerosol for inhalation by a person includes a mouthpiece, a liquid container, and a mesh assembly having a mesh material and a piezoelectric material. The mesh material is in contact with a liquid of the container. The mesh material is configured to vibrate when the piezoelectric material is actuated, whereby the aerosol is produced. The aerosol may be inhaled through the mouthpiece. The device also includes circuitry and a power supply for actuating the mesh assembly. The mouthpiece, the container, and the mesh assembly are located in-line along a longitudinal axis of the device between opposite longitudinal ends of the device, with the mesh assembly extending between and separating the mouthpiece and the container. The mesh material has a rigidity that is sufficient to prevent oscillations of varying amplitudes during actuation of the piezoelectric material of the mesh assembly for consistently producing the aerosol.

A method is provided that includes intranasally dispensing nasal wash fluid into a nasal cavity of a subject. Thereafter, a specimen sample is collected by performing an anterior nares nasal swab. The specimen sample is tested for the presence of a virus using a lateral flow immunoassay test strip. Other embodiments are also described.