A method of introducing a vapor of at least one substance into an inhalation flow path of a respiratory organ is provided. The method describes providing a carrier conformable to a surface of skin; providing the carrier with at least one substance; providing a barrier coupled to a surface of the carrier, the barrier being substantially impermeable to the substances carried by the carrier; providing a polyethylene coated material disposed within or atop the barrier and configured as a clamp for a septum of a user, wherein the polyethylene coated material is heat sealed within the barrier; and engaging the carrier to the surface of skin proximate an inhalation flow path of a respiratory organ with the barrier adapted to be interposed between the carrier and the skin to prevent the one or more substances from contacting the skin; wherein the substance is volatile and/or non-volatile; wherein the carrier is impregnated with nanocapsules during production. A vehicle for introducing a vapor is also provided.

An apparatus for use with a cartridge having an outer surface shaped to define a ridge includes a rigid piece of material configured to lock the cartridge in place by resting against the ridge, a button, configured to move the rigid piece of material from the cartridge, thereby unlocking the cartridge, upon a pushing of the button, one or more motors, and a mechanical coupling mechanism, configured to mechanically couple the motors to the cartridge while the cartridge is locked in place. Other embodiments are also described.

An apparatus includes a base, including two motors and a mechanical coupling mechanism, and a cartridge shaped to define two stators and respective pairs of ports in fluidic communication with the stators. The cartridge is removably insertable into the base and includes two rotors disposed, respectively, within the stators. The mechanical coupling mechanism is configured to mechanically couple the rotors to the motors, respectively, such that, following insertion of the cartridge into the base, the motors rotate the rotors, thereby pumping fluid through the pairs of ports. Other embodiments are also described.

A method of selecting or generating a design for a component of a patient interface device, the method including receiving a scan of at least a portion of a patient's face, receiving preference information about the patient, and generating a custom design or selecting a preexisting design for the component of the patient interface device based on the scan of at least a portion of the patient's face and the preference information, wherein a size or shape of the generated custom design for the component or selected preexisting design for the component is based on the preference information.

A cannula for providing respiratory therapy to a patient includes a first nasal prong having a proximal end attached to a cannula body and a distal end for insertion into a nare of the patient. The first nasal prong defines a lumen for a flow of breathing gas from a source of breathing gas to the nare of the patient, and the first nasal prong has a variable geometry such that a cross-sectional area of the lumen at the distal end of the first nasal prong varies with a flow rate of the breathing gas. Varying the cross-sectional area of the first nasal prong lumen with the flow rate of the breathing gas enables the first nasal prong to maintain a high velocity flow to the nare for effective flushing of the patient's airway.

The single-use safety syringe having a manual and/or automatic retracting needle preventing re-use thereof comprises a needle, a piston with a tightening seal and a cylindrical body having, at an end thereof, a connector provided with a calibrated attaching hole for the needle and open, at another end thereof, for inserting the piston, comprising, internally of the cylindrical body, a separating seal of a first chamber comprised between the separating seal and the connector in which a first active ingredient is positioned and a second chamber comprised between the separating seal and the tightening seal in which a second active ingredient is positioned, the separating seal having a connecting channel between the first and second chamber, closed by a pressure limiting valve, first engaging means further being provided, activatable for engaging the separating seal to the needle and second engaging means activatable for engaging the separating seal to the piston.

A nebulizer unit includes a housing, which includes an aerosol generator with a feed chamber disposed at one side, an ampoule receiver, an opening device with at least one opening, which is in communication with the feed chamber, and an ampoule with liquid, which comprises at least one opening, with which it can be inserted or used in the ampoule receiver, wherein the ampoule has a connection region, which interacts with a connector of the ampoule receptacle in order to hold the ampoule firmly in the ampoule receiver and to connect the openings and such that they are leak tight.

Disclosed is a method of sealing a syringe barrel having a syringe tip with a collar. The syringe tip is sealed with a resilient closure. A tamper evident syringe tip cap comprising a cap member and a sleeve member separated by an annular first breaking line is then pushed over the resilient closure, to couple the proximal end of the sleeve member with the collar. The distal end of the resilient closure is accommodated in the cap member and protrudes beyond the sleeve member. The first breaking line is bridged by a coupling strip. For use of the syringe and providing access to the closure, the first breaking line is broken by pivoting the cap member away. The sleeve member remains coupled to the collar. Further tearing the cap member downward causes breaking a second breaking line provided in the sleeve member, thereby enabling removing the entire syringe tip cap.

A patch-sized fluid delivery device may include a reusable portion and a disposable portion. The disposable portion may include components that come into contact with the fluid, while the reusable portion may include only components that do not come into contact with the fluid. Redundant systems, such as redundant controllers, power sources, motor actuators, and alarms, may be provided. Alternatively or additionally, certain components can be multi-functional, such a microphones and loudspeakers that may be used for both acoustic volume sensing and for other functions and a coil that may be used as both an inductive coupler for a battery recharger and an antenna for a wireless transceiver. Various types of network interfaces may be provided in order to allow for remote control and monitoring of the device.

A patient interface comprises a plenum chamber and a seal-forming structure. The seal-forming structure comprises a support structure arranged to support a sealing portion that is adapted to sealing engage the patient's face in use. The seal-forming structure may also include a seal biasing portion configured to inflate under pressurization within the cavity in the cushion assembly in use to extend the reach of the sealing portion and decouple the sealing portion from external forces.