A method for inducing a hibernation-like state and a device for the same is described. The method is a chemical and physical method for reducing, in a subject, a theoretical set-point temperature of a body temperature and/or a feedback gain of heat production, or for inducing a hibernation-like state in the subject, the method including applying an excitatory stimulus to pyroglutamylated RFamide peptide (QRFP)-producing neurons. A device used to implement the method is also described.

A system for removing fluid from a urinary tract includes: at least one sensor configured to detect signal(s) representative of bioelectrical impedance and communicate signal(s) representative of the impedance; and a controller. The controller is configured to: receive and process the signal(s) from the at least one sensor to determine if the impedance is above, below, or at a predetermined value; and provide a control signal, determined at least in part from the signal(s) representative of the impedance received from the at least one sensor, to a negative pressure source to apply negative pressure to a urinary catheter when the impedance is below the predetermined value and to cease applying negative pressure when the impedance is at or above the predetermined value.

A fluid dispensing device having an air expulsion system (200) with a pump (200) with an external body (210) containing a pump body (220; 270) with a pumping chamber (225) and a piston rod (230). The pump body has a proximal hollow body and a distal hollow body fixed to one another. The rod has a proximal rod part (231), a central rod part (232) and a distal rod part (233), the outside diameter of the central rod part (232) greater than the diameters of the other two. The central rod part supports a first seal (237) and a second seal (236), and the distal rod part supports a third seal (235). The proximal rod part has a central passage (234) extending beyond the first seal and opens laterally to the outside between the first and second seals. The distal hollow body contains a spring.

The disclosure provides an anesthesia machine, a veterinary anesthesia machine, and a waste gas absorption tank supporting device, the waste gas absorption tank supporting device including: a tray provided with a tray recess; and a protrusion structure provided on the tray, the protrusion structure being capable of forming a circumferential protective structure located on an outer side of the tray recess and configured to protect a waste gas absorption tank, and an inner side surface and an outer side surface of the protrusion structure being both protective surfaces capable of protecting the waste gas absorption tank. The waste gas absorption tank supporting device provided by the disclosure can effectively support waste gas absorption tanks of various sizes, so that the waste gas absorption tank is prevented from sliding off from the waste gas absorption tank supporting device during the movement of the anesthesia machine.

The present disclosure provides systems and method for electric plasma synthesis of nitric oxide. In particular, the present disclosure provides a nitric oxide (NO) generation system configured to produce a controllable output of therapeutic NO gas at the point of care.

A device (10,210) for treatment of a canal associated with an orifice includes a flexible stem portion (20, 220) adapted for insertion along the canal and having an expandable member (24, 224) carried by the stem portion (20, 220) at or adjacent the distal end. The expandable member (24, 224) is for occlusion of an inner end region of the canal. A cap (40, 240, 340) mounted on the stem portion (20, 220), configured as a receptacle (42, 242), to close an outer end of the canal and to accommodate the surface(s) about the outer end of the canal. The cap (40, 240) thereby de-fines with the expandable member (24, 224), a treatment zone, wherein the receptacle (42, 242) is adapted to receive and store treatment fluid for contact with the surface(s) about the outer end of the canal.

Methods and systems for automating surgical procedures in model organisms. The system includes a user input panel, a trained computer vision system, a server, and articulated robotic arm. The system may further include an analytical scale, an anesthesia chamber, a tube labeling system, a tissue freezing system, and a biohazard waste disposal system. The computer vision system communicates with the robotic arm to coordinate tissue collections and common research procedures such as injections via recognition models related to detection, identification, localization, and classification. The central server provides rapid synchronization of data between the local machine and a cloud account system for real-time data analytics. The anesthesia chamber provides standardized administration of anesthesia, the sample labeling system provides 2D barcoded labels according to user input, and the tissue freezing and waste disposal systems enable storage of samples and removal of carcasses following tissue collection, fully automating the necropsy.

A fluid delivery device comprises a hydraulic pump chamber having a hydraulic fluid. A fluid reservoir is coupled to the hydraulic pump chamber and is configured to contain a fluid deliverable to a patient. A first actuator is coupled to the hydraulic pump chamber and is configured to pressurize the hydraulic pump chamber and configured to transfer energy through the hydraulic pump chamber to the fluid reservoir. A second actuator is coupled to the hydraulic pump chamber and is configured to pressurize the hydraulic pump chamber and configured to transfer energy through the hydraulic pump chamber to the fluid reservoir.

Certain embodiments are directed to a laryngoscopy device and methods of use thereof, the device having a curved, hollow stylet with a handle and a flexible bougie contained at least partially within the hollow stylet, the bougie being extendable out of the end of the stylet for use in guidance of a hollow endotracheal tube.

An infusion system for subcutaneous delivery of a fluid to a subject is disclosed. The infusion system comprises a source of a fluid; a fluid delivery system; a first fluid conduit in fluid communication with the source of the fluid and the fluid delivery system; a fluid injection device configured to be inserted into the skin of a subject for delivering the fluid to the subject; a second fluid conduit in fluid communication with the fluid delivery system and the fluid injection device; and a support frame attached to the source of the fluid and the fluid delivery system, wherein the support frame is configured to mount the source of the fluid and the fluid delivery system on a region of a head of the subject. The fluid delivery system moves the fluid from the source of the fluid, through the first fluid conduit, through the second fluid conduit, and through the fluid injection device.