A fabrication process for soft-matter printed circuit boards is disclosed in which traces of liquid-phase Ga—In eutectic (eGaIn) are patterned with UV laser micromachining (UVLM). The terminals of the elastomer-sealed LM circuit connect to the surface mounted chips through vertically-aligned columns of eGaIn-coated ferromagnetic microspheres that are embedded within an interfacial elastomer layer.

An electrical interferential technique is used to determine operable treatment parameters which are then used to apply a treatment to a patient. A range of beat frequencies is applied to the patient and an indicator of autonomic nervous system activity is measured. When some degree of autonomic nervous system activity is detected, a subsequent trial is conducted using an overlaying range of frequencies, a narrower range or a single frequency, in an attempt to fine tune the reaction of the autonomic nervous system. The subsequent trial may use a different measure of activity of the autonomic nervous system. A garment having a series of electrode sites thereon may be used for a partially trained person to correctly apply electrodes to the patient's body. The treatments may be conducted while the patient is asleep.

Systems and method may be used for interfacing with a patient. Systems may include a plurality of electrodes in electrical communication with a processor. The processor may be configured to receive sense signals from electrodes and to determine the reliability of the received signal. A test tone signal comprising a test tone frequency may be applied, and the magnitude of the test tone frequency may be analyzed in the received signal. If it is determined that the magnitude of the test tone frequency is below a threshold, the system may take action, such as lowering the gain on an amplifier. Stimulation signals may be applied to the patient at a stimulation frequency simultaneously with one or both of receiving sense signals and providing the test tone signal.

A gastric electric stimulation (GES) system is disclosed which includes a processing system, and at least one of a left vagus nerve sensor (L/R Sensors) and a right vagus nerve sensor coupled to the processing system, the processing system is configured to receive a model which statistically correlates sensed compound nerve action potential (CNAP) parameters measured from at least one of left and right vagus nerves of subjects within a population to feedback surveys of the subjects corresponding to a plurality of gastric symptoms and symptom parameters, receive one or more gastric symptoms of a subject outside of the population (Subject.sub.out), determine CNAP parameters that correspond to the gastric symptoms with least severity (CNAP.sub.min), measure CNAP activity of the Subject.sub.out from the L/R sensors while modifying GES parameters for the Subject.sub.out, select the GES parameters that corresponds to the CNAP.sub.min (GES.sub.out), and output the GES.sub.out.

Devices and methods for blocking signal transmission through neural tissue. One step of a method includes placing a therapy delivery device into electrical communication with the neural tissue. The therapy delivery device includes an electrode contact having a high charge capacity material. A multi-phase direct current (DC) can be applied to the neural tissue without damaging the neural tissue. The multi-phase DC includes a cathodic DC phase and anodic DC phase that collectively produce a neural block and reduce the charge delivered by the therapy delivery device. The DC delivery can be combined with high frequency alternating current (HFAC) block to produce a system that provides effective, safe, long term block without inducing an onset response.

Described herein are techniques for improving disaster recovery, in particular disaster recovery pertaining to data transfer requests. The data transfer request can be received by each of multiple deployments; however, only a primary deployment can process the request. The data transferred by the primary deployment may be replicated in the secondary deployments. In response to a failover event, one of the secondary deployments can be designated as the new primary development and continue the data transfer based on the data transfer request and the replication information received from the old primary deployment prior to the failover.

Systems and methods are described herein for evaluation and configuration cardiac therapy. The systems and methods may monitor electrical activity using a plurality of external electrodes and may utilize multiple-electrode cardiac metrics such as electrical heterogeneity information, single-electrode cardiac metrics, and vectorcardiographic metrics to determine and select one or more paced settings from a plurality of different paced settings.

In some examples, a medical device system includes a first implantable medical device. The first implantable medical device (IMD) may comprise circuitry configured to at least one of deliver a therapy to a patient or sense a physiological signal from the patient; generate stimulation deliverable to a patient; a first rechargeable power source; and a secondary coil coupled to the first rechargeable power source, the secondary coil configured to charge the first rechargeable power source via inductive coupling with a primary coil of an external charging device. The medical device system may comprise processing circuitry configured to control charging of the first rechargeable power source based on a charge state of a second rechargeable power source of a second IMD.

An apparatus can have a computing component. The computing component can be configured to receive a wireless transmission from an implanted device, verify an identity of the implanted device by verifying security data from the implanted device, and perform an authentication procedure, in response to verifying the identity of the implanted device, to determine whether the transmission is authentic by determining whether a digital signature of the transmission is authentic. The apparatus can be configured to wirelessly charge the implanted device in response to the computing component determining that the digital signature is authentic.

Provided herein are methods of treating a patient comprising providing a medical apparatus comprising an external system and an implantable system, implanting the implantable system, and delivering at least one of power or data to the implantable system with the external system. The external system comprises: at least one external antenna configured to transmit a first transmission signal to the implantable system; an external transmitter configured to drive the at least one external antenna; an external power supply; and an external controller. The implantable system comprises: at least one implantable antenna configured to receive the first transmission signal from the first external device; an implantable receiver; at least one implantable functional element configured to interface with the patient; an implantable controller; an implantable energy storage assembly; and an implantable housing surrounding at least the implantable controller and the implantable receiver. Medical apparatus are also provided.