A device for reducing foreign body response in a subject caused by an electrode implanted in a subject's tissue. A base is secured to the subject, having a base aperture in proximity to the target site. The base can receive and align a body thereon. A body contains a chamber extending between a chamber aperture, aligned with the base aperture, at one end and a chamber opening at an opposite end. The chamber contains an acoustic coupling medium, such as polyvinyl alcohol cryogel, transmits acoustic vibrations from a transducer without altering their frequency. The transducer is mounted to the device and is configured to transmit acoustic vibrations into the chamber and through said acoustic coupling medium to the subject tissue at the target site, creating an acoustic field in the target site sufficient to reduce foreign body response in the subject where the electrode contacts the target tissue.

A device for reducing foreign body response in a subject caused by an electrode implanted in a subject's tissue. A base is secured to the subject, having a base aperture in proximity to the target site. The base can receive and align a body thereon. A body contains a chamber extending between a chamber aperture, aligned with the base aperture, at one end and a chamber opening at an opposite end. The chamber contains an acoustic coupling medium, such as polyvinyl alcohol cryogel, transmits acoustic vibrations from a transducer without altering their frequency. The transducer is mounted to the device and is configured to transmit acoustic vibrations into the chamber and through said acoustic coupling medium to the subject tissue at the target site, creating an acoustic field in the target site sufficient to reduce foreign body response in the subject where the electrode contacts the target tissue.

Disclosed herein are apparatuses, systems, kits, and methods for treating skin, such as skin tightening or for treating diseases, disorders, and conditions that would benefit from tissue area or volume reduction, skin restoration, skin tightening, skin lifting, and/or skin repositioning and/or for generally improving skin function or appearance (e.g., the removal of unwanted skin features or irregularities such as sebaceous glands, sweat glands, hair follicles, necrosis, and fibrosis). Such apparatuses, systems, kits, and methods comprise an apparatus having a handheld main body and a detachably attachable tip comprising one or more needles.

Provided are a brain stimulation system, method, apparatus and storage medium based on artificial intelligence. The system includes: a plurality of brain stimulation terminals and a cloud platform. The cloud platform is configured to, with artificial intelligence algorithm especially machine learning and deep learning, generate multi-dimensional psychological big data using physiological data and psychological state evaluation parameters gotten from the plurality of brain stimulation terminals and established models of algorithm for disease diagnosis. The brain stimulation terminal is configured to analyze the physiological data and psychological state evaluation parameters of a target subject, measure a mental state of the target subject, obtain brain stimulation parameters required for the target subject according to the mental state, and generate corresponding non-invasive brain stimulation for the target subject according to the brain stimulation parameters based on the multi-dimensional big data through the artificial intelligence algorithm.

Provided are a brain stimulation system, method, apparatus and storage medium based on artificial intelligence. The system includes: a plurality of brain stimulation terminals and a cloud platform. The cloud platform is configured to, with artificial intelligence algorithm especially machine learning and deep learning, generate multi-dimensional psychological big data using physiological data and psychological state evaluation parameters gotten from the plurality of brain stimulation terminals and established models of algorithm for disease diagnosis. The brain stimulation terminal is configured to analyze the physiological data and psychological state evaluation parameters of a target subject, measure a mental state of the target subject, obtain brain stimulation parameters required for the target subject according to the mental state, and generate corresponding non-invasive brain stimulation for the target subject according to the brain stimulation parameters based on the multi-dimensional big data through the artificial intelligence algorithm.

Methods and systems for modulation and mapping of brain tissue in a subject using an ultrasound assembly are provided. An exemplary method for modulation uses an ultrasound assembly including a housing and an ultrasound transducer joined to the housing. The method includes securing the housing to the head of the subject with the ultrasound transducer aligned with a region of the brain tissue to target the region of the brain tissue for modulating, and providing focused ultrasound at an acoustic pressure to the targeted region using the ultrasound transducer to induce cavitation proximate the targeted region. The method further includes detecting a cavitation signal magnitude from the induced cavitation corresponding to the acoustic pressure and modulating the targeted region.

Methods and systems for modulation and mapping of brain tissue in a subject using an ultrasound assembly are provided. An exemplary method for modulation uses an ultrasound assembly including a housing and an ultrasound transducer joined to the housing. The method includes securing the housing to the head of the subject with the ultrasound transducer aligned with a region of the brain tissue to target the region of the brain tissue for modulating, and providing focused ultrasound at an acoustic pressure to the targeted region using the ultrasound transducer to induce cavitation proximate the targeted region. The method further includes detecting a cavitation signal magnitude from the induced cavitation corresponding to the acoustic pressure and modulating the targeted region.

The present disclosure provides implants, sensor modules, networks, and methods configured to establish transcutaneous power and transcutaneous bidirectional data communication using ultrasound signals between two or more medical devices located on and within a body of a patient.

The present disclosure provides implants, sensor modules, networks, and methods configured to establish transcutaneous power and transcutaneous bidirectional data communication using ultrasound signals between two or more medical devices located on and within a body of a patient.

An ultrasound-emitting apparatus for applying selective treatments to hypodermic tissue (adipose tissue and connective tissue) in body rejuvenation/remodelling processes, by an electric-pulse generator, an ultrasound transducer (3), an electronic control device (6) provided with specific software that controls the frequency, voltage and work cycle of the pulse generator; and application means (4) for orienting and directing the acoustic field on the area of the patient/user to be treated, wherein, in each firing, the transducer emits an acoustic field with an energy density no greater than 0.7 W/cm.sup.2 and a minimum emission duration of 100 ms. Preferably, the transducer emits either at a single frequency or in a frequency sweep, in a frequency range of 185-333 kHz, and even more preferably at 244 kHz.