A general serum procedure for all of pathogens with protein coding on an outer shell of the pathogens, comprises entering dead pathogens and their dead genomes to eliminate pathogens and cancer genes in humans and animals. A device for detecting pathogens in human body, animals, plants, water bodies, and air without blood test observes the spectral signature emitting from the human body and the water to match for any pathogens within the device’s database and uses electrostatic properties of the pathogens and their genomes to catch them.

A general serum procedure for all of pathogens with protein coding on an outer shell of the pathogens, comprises entering dead pathogens and their dead genomes to eliminate pathogens and cancer genes in humans and animals. A device for detecting pathogens in human body, animals, plants, water bodies, and air without blood test observes the spectral signature emitting from the human body and the water to match for any pathogens within the device’s database and uses electrostatic properties of the pathogens and their genomes to catch them.

An ultrasonic surgical blade includes a body having a proximal end, a distal end, and an outer surface. The distal end is movable relative to a longitudinal axis in accordance with ultrasonic vibrations applied to the proximal end. At least a portion of the outer surface of the body comprises a lubricious coating adhered thereto. The lubricious coating has a coefficient of friction that is less than the coefficient of friction of the outer surface of the body.

An ultrasonic surgical blade includes a body having a proximal end, a distal end, and an outer surface. The distal end is movable relative to a longitudinal axis in accordance with ultrasonic vibrations applied to the proximal end. At least a portion of the outer surface of the body comprises a lubricious coating adhered thereto. The lubricious coating has a coefficient of friction that is less than the coefficient of friction of the outer surface of the body.

A device for therapeutic neuromodulation in a nasal region can include, for example, a shaft and a therapeutic element at a distal portion of the shaft. The shaft can locate the distal portion intraluminally at a target site inferior to a patient's sphenopalatine foramen. The therapeutic element can include an energy delivery element configured to therapeutically modulate postganglionic parasympathetic nerves at microforamina of a palatine bone of the human patient for the treatment of rhinitis or other indications. In other embodiments, the therapeutic element can be configured to therapeutically modulate nerves that innervate the frontal, ethmoidal, sphenoidal, and maxillary sinuses for the treatment of chronic sinusitis.

A device for therapeutic neuromodulation in a nasal region can include, for example, a shaft and a therapeutic element at a distal portion of the shaft. The shaft can locate the distal portion intraluminally at a target site inferior to a patient's sphenopalatine foramen. The therapeutic element can include an energy delivery element configured to therapeutically modulate postganglionic parasympathetic nerves at microforamina of a palatine bone of the human patient for the treatment of rhinitis or other indications. In other embodiments, the therapeutic element can be configured to therapeutically modulate nerves that innervate the frontal, ethmoidal, sphenoidal, and maxillary sinuses for the treatment of chronic sinusitis.

Some embodiments of the invention relate to an applicator for applying ultrasound energy to a tissue volume, comprising: an array comprising a plurality of ultrasound transducers, the transducers arranged side by side, the transducers configured to emit unfocused ultrasound energy suitable to thermally damage at least a portion of the tissue volume, each of the transducers comprising a coating thin enough so as not to substantially affect heat transfer via the coating to the tissue; and a cooling module configured to apply cooling via the transducers to prevent overheating of a surface of the tissue volume being contacted by the transducers.

Methods and systems for modulating intraosseous nerves (e.g., nerves within bone) are provided. For example, the methods and systems described herein may be used to modulate (e.g., denervate, ablate) basivertebral nerves within vertebrae. The modulation of the basivertebral nerves may facilitate treatment of chronic back pain. The modulation may be performed by a neuromodulation device (e.g., an energy delivery device).

[Problem] To provide a cosmetic mask which imparts effective stimulation to the appropriate position and has a tightening effect. [Solution] This cosmetic mask is worn on the face of a user, is able to cover at least the cheeks, and is equipped with a pair of simulators which impart electric or ultrasonic stimulation to a location corresponding to either the zygomatic muscle or masseter muscle of the user. The cosmetic mask may be equipped with a stimulator fitting unit for fitting the stimulators to a cheek position, and maybe constituted so that at least some of the stimulators are detachable. The cosmetic mask may also be equipped with a nosepiece which matches the protruding shape of the nose, a left-right fitting portion which is fitted while applying tensile force to the left and right sides of the face, and a vertical fitting portion which is fitted while applying tensile force from the lower surface of the mandible over both sides of the face to the top of the head.

[Problem] To provide a cosmetic mask which imparts effective stimulation to the appropriate position and has a tightening effect. [Solution] This cosmetic mask is worn on the face of a user, is able to cover at least the cheeks, and is equipped with a pair of simulators which impart electric or ultrasonic stimulation to a location corresponding to either the zygomatic muscle or masseter muscle of the user. The cosmetic mask may be equipped with a stimulator fitting unit for fitting the stimulators to a cheek position, and maybe constituted so that at least some of the stimulators are detachable. The cosmetic mask may also be equipped with a nosepiece which matches the protruding shape of the nose, a left-right fitting portion which is fitted while applying tensile force to the left and right sides of the face, and a vertical fitting portion which is fitted while applying tensile force from the lower surface of the mandible over both sides of the face to the top of the head.