The present discussion relates to structures and devices to facilitate application of an ultrasound therapy beam to a target anatomic region in a replicable manner. In certain aspects, adjustable positioning structures are described that allow a general probe positioning structure to be configured for a specific patient in a manner that allows the device to be used repeatedly to target the anatomic region, even when in non-clinical settings. In other aspects, a probe positioning structure is fabricated that is specific to a respective patient anatomy, such that use of the probe positioning structure provides repeatable targeting of the target anatomic region, even when in non-clinical settings.

An ultrasound probe including a probe body having a mounting area and a flexible lip around said mounting area for sealing a space between the mounting area and a subject contacted by the ultrasound probe; and a number of ultrasound transducer elements mounted in the mounting area. The probe body further includes an inlet to said space and an outlet from said space for facilitating a fluid flow through said space when sealed. Also included are an ultrasound system including such an ultrasound probe and a method of subjecting a subject to ultrasound waves generated with such an ultrasound probe.

An ultrasound probe including a probe body having a mounting area and a flexible lip around said mounting area for sealing a space between the mounting area and a subject contacted by the ultrasound probe; and a number of ultrasound transducer elements mounted in the mounting area. The probe body further includes an inlet to said space and an outlet from said space for facilitating a fluid flow through said space when sealed. Also included are an ultrasound system including such an ultrasound probe and a method of subjecting a subject to ultrasound waves generated with such an ultrasound probe.

To alleviate information-dependent behavior by using a mobile terminal of a user of the mobile terminal. A mobile terminal including a first signal generator that generates a frequency signal in the audible band, a second signal generator that generates a high-frequency signal in a frequency band higher than the audible band, a speaker that converts the high-frequency signal into a corresponding high-frequency sound, and a timing controller that controls timing of the generation of the high-frequency signal to be a timing that does not correlate with the timing of the generation of the frequency signal in the audible band is provided.

A method for aesthetic soft tissue treatment includes placing at least one applicator in contact with the patient's body. The applicator has at least one electrode. Electrotherapy and radio frequency therapy are provided to the soft tissue, optionally with overlay or sequentially. A handheld applicator may be used, with the applicator moving during the therapy, which may provide muscle stimulation in the patient, or provide an analgesic effect during the treatment. A spacing object may be positioned between the skin of the patient and the applicator.

A method for aesthetic soft tissue treatment includes placing at least one applicator in contact with the patient's body. The applicator has at least one electrode. Electrotherapy and radio frequency therapy are provided to the soft tissue, optionally with overlay or sequentially. A handheld applicator may be used, with the applicator moving during the therapy, which may provide muscle stimulation in the patient, or provide an analgesic effect during the treatment. A spacing object may be positioned between the skin of the patient and the applicator.

The method includes excitation during which an internal mechanical stress is generated in an excitation zone, and imaging by acquiring signals during movements generated by the mechanical stress in the visco-elastic medium in response to the internal mechanical stress in an. imaging zone that includes the excitation zone. The method further includes calculating a quantitative index associated with the rheological properties of the visco-elastic medium at least at one point of the imaging zone situated at a given depth outside the excitation zone. The quantitative index is representative of a comparison between signals acquired during the movements generated in response to the mechanical stress at least at one point of the excitation zone situated at the given depth, and signals acquired during the movements generated in response to the mechanical stress at at least the point of the imaging zone situated outside the excitation zone.

Disclosed are methods of obtaining zero vergence ultrasound waves for providing sonodynamic therapy with ultrasound waves. The method includes coupling a sonodynamic therapy device with an array of flat piezoelectric transducers to a skin surface. A controller is configured to generate an electrical drive signal at a frequency, modulate the drive signal, and drive the transducer with the modulated drive signal at the frequency to produce a zero vergence ultrasound wave to produce an average acoustic intensity sufficient to activate a sonosensitizer in a treatment region without damaging healthy cells in the treatment region.

Disclosed are methods of obtaining zero vergence ultrasound waves for providing sonodynamic therapy with ultrasound waves. The method includes coupling a sonodynamic therapy device with an array of flat piezoelectric transducers to a skin surface. A controller is configured to generate an electrical drive signal at a frequency, modulate the drive signal, and drive the transducer with the modulated drive signal at the frequency to produce a zero vergence ultrasound wave to produce an average acoustic intensity sufficient to activate a sonosensitizer in a treatment region without damaging healthy cells in the treatment region.

A vibration transmitting member transmits ultrasonic vibration generated by an ultrasonic transducer from a proximal side toward a distal side. The vibration transmitting member includes a connection connected to the ultrasonic transducer. When a reference vibration node, which is located most proximally among vibration nodes occurring on the distal side relative to the connection, is defined, while the vibration transmitting member vibrates at a resonance frequency in a predetermined frequency range, a cross-sectional area decreasing part is provided between the connection and the reference vibration node. In the cross-sectional area decreasing part, a cross-sectional area perpendicular to a longitudinal direction gradually decreases from the distal side toward the proximal side.