The present disclosure relates to processes for the manufacture of compositions containing amine fluorides and mixtures of these amine fluorides. Related compositions and methods of use are further disclosed.

The present disclosure relates to processes for the manufacture of compositions containing amine fluorides and mixtures of these amine fluorides. Related compositions and methods of use are further disclosed.

Dental desensitizing solutions and methods of using the solutions are disclosed. The solution may include an active ingredient, the active ingredient, when applied to a tooth, being configured to react with calcium in the tooth to produce a plurality of acid-resistant crystals that at least partially occlude dentinal tubules in the tooth. The solution may include a solubility enhancer, the solubility enhancer increasing the solubility of the active ingredient in the solution. The active ingredient may be oxalic acid, potassium salt dihydrate and the solubility enhancer may be sodium hydroxide, however, other active ingredients and solubility enhancers are disclosed. The solution may be applied to the tooth dentin and/or cementum to reduce hypersensitivity or pain from certain stimuli. The solution may increase the solubility of the active ingredient by at least 1.0 g/L at a given temperature. The solution may include at least 0.3 g/L of the solubility enhancer.

A calcium phosphate-based core-shell structured material, a method for preparing the same, and an oral care composition using the same are provided. The calcium phosphate-based core-shell structured material includes an amorphous calcium phosphate (ACP) core and a β-tricalcium phosphate (β-TCP) shell covering the core. The method includes a first sintering step and a second sintering step. The first sintering step is to sinter an ACP material at between 700° C. and 800° C. to obtain an α-TCP shell. The second sintering step allows the α-TCP shell to form into the β-TCP shell by sintering at between 800° C. and 900° C. The oral care composition includes a calcium phosphate mixture and an orally receivable carrier. The calcium phosphate mixture includes a powder of the calcium phosphate-based core-shell structured material and a tricalcium phosphate powder mixed in a weight ratio from 3:5 to 3:7.

A calcium phosphate-based core-shell structured material, a method for preparing the same, and an oral care composition using the same are provided. The calcium phosphate-based core-shell structured material includes an amorphous calcium phosphate (ACP) core and a β-tricalcium phosphate (β-TCP) shell covering the core. The method includes a first sintering step and a second sintering step. The first sintering step is to sinter an ACP material at between 700° C. and 800° C. to obtain an α-TCP shell. The second sintering step allows the α-TCP shell to form into the β-TCP shell by sintering at between 800° C. and 900° C. The oral care composition includes a calcium phosphate mixture and an orally receivable carrier. The calcium phosphate mixture includes a powder of the calcium phosphate-based core-shell structured material and a tricalcium phosphate powder mixed in a weight ratio from 3:5 to 3:7.

Compositions are disclosed herein that comprise a mixture of at least one Albizia extract and a Magnolia extract. In some embodiments, the composition comprises a mixture of at least one Albizia extract enriched for one or more macrocyclic alkaloids and at least one Magnolia extract enrich for one or more lignans.

Compositions are disclosed herein that comprise a mixture of at least one Albizia extract and a Magnolia extract. In some embodiments, the composition comprises a mixture of at least one Albizia extract enriched for one or more macrocyclic alkaloids and at least one Magnolia extract enrich for one or more lignans.

The present disclosure provides an oral care composition including a water-miscible base component, an amorphous calcium phosphate remineralizing component including a water-soluble or partially water-soluble calcium component and a water-soluble inorganic phosphate component, and a tartar control component, wherein the oral care composition provides enamel fluoride uptake activity and tartar control activity.

The present disclosure provides an oral care composition including a water-miscible base component, an amorphous calcium phosphate remineralizing component including a water-soluble or partially water-soluble calcium component and a water-soluble inorganic phosphate component, and a tartar control component, wherein the oral care composition provides enamel fluoride uptake activity and tartar control activity.

Disclosed are high-porosity protein particles useful for carrying one or more agents of interest, methods for their manufacture and use, and products comprising them.