The invention is directed toward mutant, non-wild-type organophosphorus acid anhydrolase enzymes having three site mutations, methods of production, and methods of use to effectively degrade toxic organophosphorus compounds, most preferably GP (2,2-dimethylcyclopentyl methylphosphonofluoridate).

Provided is a protective mask that is highly comfortable to wear. A protective mask includes: a face piece; an eyepiece attached to the face piece; and a lip extending from an outer circumference of the face piece in a direction crossing the face piece, in which at least a part of the lip includes a face contact portion capable of coming into contact with a face of a wearer, the face contact portion is formed from a silicone rubber, the face piece and the lip are formed from a gas impermeable material except for the face contact portion, and the gas impermeable material and the silicone rubber are joined together along the boundary between the gas impermeable material and the silicone rubber.

Provided is a protective mask that is highly comfortable to wear. A protective mask includes: a face piece; an eyepiece attached to the face piece; and a lip extending from an outer circumference of the face piece in a direction crossing the face piece, in which at least a part of the lip includes a face contact portion capable of coming into contact with a face of a wearer, the face contact portion is formed from a silicone rubber, the face piece and the lip are formed from a gas impermeable material except for the face contact portion, and the gas impermeable material and the silicone rubber are joined together along the boundary between the gas impermeable material and the silicone rubber.

Decontaminating materials and methods of making and using the same are provided. The material comprises a network comprising electrospun polymeric nanofibers and at least 50 grams of metal organic framework (MOF) microparticles per m.sup.2 of the network based on the entire area of the network. A composition of the polymeric nanofibers comprises a hydroscopic polymer. An area of the material is defined by an outer surface of the network. The MOF microparticles are retained between the polymeric nanofibers in the network and are configured to decontaminate a chemical threat agent in contact with the material.

Decontaminating materials and methods of making and using the same are provided. The material comprises a network comprising electrospun polymeric nanofibers and at least 50 grams of metal organic framework (MOF) microparticles per m.sup.2 of the network based on the entire area of the network. A composition of the polymeric nanofibers comprises a hydroscopic polymer. An area of the material is defined by an outer surface of the network. The MOF microparticles are retained between the polymeric nanofibers in the network and are configured to decontaminate a chemical threat agent in contact with the material.