A centrifugal separator and a method for separation of particles from a gas stream is disclosed. The separator includes a frame, a gas inlet and a gas outlet. A centrifugal rotor is arranged to be rotatable in the frame around a rotational axis and includes a separating member. A central gas chamber in the rotor communicates with a radially inner portion of the separating member and the gas outlet. A space surrounding the rotor communicates with a radially outer portion of the separating member and the gas inlet. A drive provides rotation of the centrifugal rotor for separating particles from the gas stream being conducted from the space surrounding the rotor, through the separation member and towards the central gas chamber. A ring-formed sealing arranged between and in sealing contact with the first frame portion and the centrifugal rotor. This improves the separation performance of a centrifugal separator for separation of particles from a gas stream, by reducing pressure losses and leakage from the central gas chamber.

A centrifugal separator and a method for separation of particles from a gas stream is disclosed. The separator includes a frame, a gas inlet and a gas outlet. A centrifugal rotor is arranged to be rotatable in the frame around a rotational axis and includes a separating member. A central gas chamber in the rotor communicates with a radially inner portion of the separating member and the gas outlet. A space surrounding the rotor communicates with a radially outer portion of the separating member and the gas inlet. A drive provides rotation of the centrifugal rotor for separating particles from the gas stream being conducted from the space surrounding the rotor, through the separation member and towards the central gas chamber. A ring-formed sealing arranged between and in sealing contact with the first frame portion and the centrifugal rotor. This improves the separation performance of a centrifugal separator for separation of particles from a gas stream, by reducing pressure losses and leakage from the central gas chamber.

Systems and methods are provided for depleting platelets from blood. The system includes a multi-stage blood separation chamber in which blood is separated into red blood cells and platelet-rich plasma. The platelet-rich plasma is conveyed from a first stage of the chamber to a second stage, where it is separated into platelets and platelet-poor plasma. The platelet-poor plasma is conveyed out of the chamber while the platelets are allowed to accumulate in the second stage of the chamber. When a controller of the system has determined that the maximum chamber capacity of platelets has been accumulated in the second stage of the chamber, the platelets are conveyed out of the chamber to a waste container. The cycle of separating blood into its components, accumulating platelets in the chamber, and then flushing the platelets from the chamber is repeated until a target platelet concentration of the blood is achieved.

Systems and methods are provided for depleting platelets from blood. The system includes a multi-stage blood separation chamber in which blood is separated into red blood cells and platelet-rich plasma. The platelet-rich plasma is conveyed from a first stage of the chamber to a second stage, where it is separated into platelets and platelet-poor plasma. The platelet-poor plasma is conveyed out of the chamber while the platelets are allowed to accumulate in the second stage of the chamber. When a controller of the system has determined that the maximum chamber capacity of platelets has been accumulated in the second stage of the chamber, the platelets are conveyed out of the chamber to a waste container. The cycle of separating blood into its components, accumulating platelets in the chamber, and then flushing the platelets from the chamber is repeated until a target platelet concentration of the blood is achieved.

An attachment fitting is attached inside a rotor hole. The attachment fitting is made up of a main body, first and second pieces disposed in a piece placement hole formed in the main body so as to pass therethrough in a direction orthogonal to a rotation central axis of a rotor, a leaf spring including two arm portions, and a retainer that is mounted on the main body and puts a base of the leaf spring between the retainer and the main body. The first and second pieces have grooves into which the arm portions of the leaf spring are inserted. When the rotor rotates, the first and second pieces protrude from the piece placement hole by the centrifugal force against the spring force of the leaf spring and make contact with a rotor coupling portion of a shaft. In a structure that allows the rotor to be attached to the shaft by simply being put onto the shaft, assembly on the rotor's side can be easily performed.

An attachment fitting is attached inside a rotor hole. The attachment fitting is made up of a main body, first and second pieces disposed in a piece placement hole formed in the main body so as to pass therethrough in a direction orthogonal to a rotation central axis of a rotor, a leaf spring including two arm portions, and a retainer that is mounted on the main body and puts a base of the leaf spring between the retainer and the main body. The first and second pieces have grooves into which the arm portions of the leaf spring are inserted. When the rotor rotates, the first and second pieces protrude from the piece placement hole by the centrifugal force against the spring force of the leaf spring and make contact with a rotor coupling portion of a shaft. In a structure that allows the rotor to be attached to the shaft by simply being put onto the shaft, assembly on the rotor's side can be easily performed.

Systems and methods are provided for depleting platelets from blood. The system includes a multi-stage blood separation chamber in which blood is separated into red blood cells and platelet-rich plasma. The platelet-rich plasma is conveyed from a first stage of the chamber to a second stage, where it is separated into platelets and platelet-poor plasma. The platelet-poor plasma is conveyed out of the chamber while the platelets are allowed to accumulate in the second stage of the chamber. When a controller of the system has determined that the maximum chamber capacity of platelets has been accumulated in the second stage of the chamber, the platelets are conveyed out of the chamber to a waste container. The cycle of separating blood into its components, accumulating platelets in the chamber, and then flushing the platelets from the chamber is repeated until a target platelet concentration of the blood is achieved.

Systems and methods are provided for depleting platelets from blood. The system includes a multi-stage blood separation chamber in which blood is separated into red blood cells and platelet-rich plasma. The platelet-rich plasma is conveyed from a first stage of the chamber to a second stage, where it is separated into platelets and platelet-poor plasma. The platelet-poor plasma is conveyed out of the chamber while the platelets are allowed to accumulate in the second stage of the chamber. When a controller of the system has determined that the maximum chamber capacity of platelets has been accumulated in the second stage of the chamber, the platelets are conveyed out of the chamber to a waste container. The cycle of separating blood into its components, accumulating platelets in the chamber, and then flushing the platelets from the chamber is repeated until a target platelet concentration of the blood is achieved.

An autotransfusion system for separating fluid constituents includes a centrifuge housing and a rotatable driving member mounted within the centrifuge housing. The rotatable driving member is configured to receive therein and rotationally engage any one of a plurality of centrifuge bowls with different heights. In some embodiments, the centrifuge bowl is integrated with a fluid line organizer to provide for easy and efficient organization of a plurality of different fluid lines incorporated into the autotransfusion system. In some embodiments, the centrifuge bowl and fluid line organizer are easily and efficiently coupled to the centrifuge housing for autotransfusion processing. After autotransfusion processing, the centrifuge bowl and fluid line organizer are easily and efficiently decoupled from the centrifuge housing and discarded.

An autotransfusion system for separating fluid constituents includes a centrifuge housing and a rotatable driving member mounted within the centrifuge housing. The rotatable driving member is configured to receive therein and rotationally engage any one of a plurality of centrifuge bowls with different heights. In some embodiments, the centrifuge bowl is integrated with a fluid line organizer to provide for easy and efficient organization of a plurality of different fluid lines incorporated into the autotransfusion system. In some embodiments, the centrifuge bowl and fluid line organizer are easily and efficiently coupled to the centrifuge housing for autotransfusion processing. After autotransfusion processing, the centrifuge bowl and fluid line organizer are easily and efficiently decoupled from the centrifuge housing and discarded.