Patent classifications
B04B13/00
CENTRIFUGE ROTOR FOR CENTRIFUGING A SAMPLE, RELATED CENTRIFUGE AND MEASUREMENT METHOD
A rotor comprises a support intended to be mounted rotatable around a rotation axis in a centrifuge enclosure. The support having at least one housing for receiving the sample. At least one electrically powered sensor held by the support, configured to measure a property of the sample. A contactless power receiver, configured to receive electrical power without contact from a contactless power transmitter, the contactless power receiver being carried by the support and being jointly rotatable with the support, the contactless power receiver being electrically connected to the at least one sensor to electrically power the at least one sensor during a rotation of the support.
Method and Device for Portable and Energy Efficient Centrifugation
Embodiments of a portable and compact centrifugal system with methods of energy efficient centrifugation are described. The centrifugal system may be used to separate biological samples contained in conventional laboratory tubes and may be powered by a set of battery cells. The centrifugal system may comprise a vibration damping system which may comprise a tuned mass damper with a damper mass, a damper wall, and an elastic coupler. Many features such as the device's voltages, vibration damping methods, firmware, circuitry, component placement, and material required careful consideration, experimentation, and selection to converge into a functional product. Centrifugation of biological samples typically requires bulky instruments that cannot be readily moved, which can prove inconvenient for remote areas and third world countries. Biological sample quality also degrades outside the body over time, so immediate access to a centrifugal system can improve sample quality.
Method and Device for Portable and Energy Efficient Centrifugation
Embodiments of a portable and compact centrifugal system with methods of energy efficient centrifugation are described. The centrifugal system may be used to separate biological samples contained in conventional laboratory tubes and may be powered by a set of battery cells. The centrifugal system may comprise a vibration damping system which may comprise a tuned mass damper with a damper mass, a damper wall, and an elastic coupler. Many features such as the device's voltages, vibration damping methods, firmware, circuitry, component placement, and material required careful consideration, experimentation, and selection to converge into a functional product. Centrifugation of biological samples typically requires bulky instruments that cannot be readily moved, which can prove inconvenient for remote areas and third world countries. Biological sample quality also degrades outside the body over time, so immediate access to a centrifugal system can improve sample quality.
Continuous flow separation chamber
A continuous flow centrifuge bowl includes a rotatable outer body, and a top and bottom core that are rotatable with the outer body. The bottom core has a wall extending proximally from a bottom wall. The proximally extending wall is radially outward from at least a portion of the top core and, together with the top core, defines a primary separation region in which initial separation of the whole blood occurs. The bowl may also have a secondary separation region located between the top core and the outer body, and a rotary seal that couples an inlet port and two outlet ports to the outer body. The inlet port may be connected to an inlet tube that extends distally into a whole blood introduction region. Additionally, one of the outlet ports may be connected to an extraction tube that extends into a region below the bottom core.
Thermal regulation of rotors during centrifugation
The present invention provides centrifuges (e.g., analytical centrifuges) comprising a cooling assembly having a cooling surface disposed inside the centrifuge chamber and spaced apart from the rotor. The cooling surface disposed inside the centrifuge chamber, spaced apart from the rotor, and configured to exchange heat between the cooling assembly and the rotor, the thermal element thermally coupled to the cooling surface, and configured to control the temperature of the cooling surface.
CENTRIFUGE AND METHOD FOR OPERATING A CENTRIFUGE
A centrifuge includes a rotatable rotor and an assembly that is stationary during operation. The rotatable rotor is rotatably mounted in or on the stationary assembly by one or more mounting devices. The rotatable rotor has a rotatable drum and a drive element for rotating the drum as well as one or more electrical loads located on or in the rotor. The centrifuge includes at least one battery is also located on or in the rotor in order to supply the at least one load or the plurality of loads with electrical power. The load can include a data memory in the rotor or on the rotor. At least one actuator is provided as the at least one load.
CENTRIFUGE AND METHOD FOR OPERATING A CENTRIFUGE
A centrifuge includes a rotatable rotor and an assembly that is stationary during operation. The rotatable rotor is rotatably mounted in or on the stationary assembly by one or more mounting devices. The rotatable rotor has a rotatable drum and a drive element for rotating the drum as well as one or more electrical loads located on or in the rotor. The centrifuge includes at least one battery is also located on or in the rotor in order to supply the at least one load or the plurality of loads with electrical power. The load can include a data memory in the rotor or on the rotor. At least one actuator is provided as the at least one load.
Blood separation systems and methods employing centrifugal and spinning membrane separation techniques
Systems and methods are provided for separating blood into two or more components. A blood separation system includes a blood separation device and a fluid flow circuit configured to be mounted to the blood separation device. The blood separation device includes a centrifugal separator and a spinning membrane separator drive unit incorporated into a common case, which allows for fluid separation by two different methods. Depending on the separation procedure to be carried out, the fluid flow circuit paired with the blood separation device may include only one separation chamber configured to be mounted to the centrifugal separator or spinning membrane separator drive unit or two separation chambers, with one being mounted to the centrifugal separator and the other to the spinning membrane separator drive unit. The system may be used to separate and collect any combination of red blood cells, plasma, and platelets.
SEPARATING PARTICLES THROUGH CENTRIFUGAL SEDIMENTATION
A method of separating particles (P) having different sedimentation velocities in a fluid sample (30) through centrifugal sedimentation comprises enclosing the sample (30) and rotating the sample about a primary axis (12) outside the sample at a first rotational speed (Ω), and about a secondary axis (22) located in the center of the sample at a second rotational speed (ξ), for subjecting the sample to a varying centrifugal field until each particle (P) has settled at a position which depends on the sedimentation velocity of the particle.
Method and apparatus for controlling a focus point of a stationary beam focusing on a sample in a rotating cartridge placed in a rotating disc
Provided are methods and apparatuses for controlling a position of a target point on a processing result relative to a focus point of a focusing sensor system for determining properties of the processing result. The method includes the steps of determining an initial focus point of the focusing sensor system, controlling rotation of the cartridge and disc, checking whether the initial focus point of the focusing sensor system corresponds to the target point on the processing result, comparing (x, y) target positions in captured images with the initial focus point of the focusing sensor system, adjusting rotation of the cartridge and disc such that the focus point of the focusing sensor system corresponds to the target point on the processing result, and detecting and examining signals received from the focusing sensor system for determining properties of the processing result.