A fluid mixer includes a flow splitter and a mixing chamber. The flow splitter includes an inlet for receiving a flow of fluid and is configured to split the flow of fluid into first and second fluid streams. The second fluid stream has a higher density than the first fluid stream. The mixing chamber includes a first inlet, a second inlet and a mixing well. The second inlet is positioned below the first inlet. The second inlet of the mixing chamber is configured to receive the first fluid stream and the first inlet of the mixing chamber is configured to receive the second fluid stream to promote mixing of the first and second streams in the mixing well.

Multistage deterministic lateral displacement devices, methods of forming the devices, and methods of separating a fluid mixture including particles having three or more particle sizes generally include a first module and at least one additional module. Each module includes a condenser portion and a separate portion. The condenser portion is generally configured to focus a streamline of all particles to a center of a channel whereas the separator separates the streamline of all particles into two different streamlines. One of the streamlines focuses the largest particles in the fluid mixture along a sidewall of the channel and the other streamline of smaller particles is between opposing sidewalls that define the channel. Each additional module can be used to further separate the largest particles remaining in the fluid mixture from the smaller particles.

The present disclosure relates to a system, generator and method for generating nanobubbles or nanodroplets and treating a multi-component mixture, and in particular for treating biogas and wastewater. The method comprises using nanobubbles of a gas component, and wastewater, to form hydrates in a treatment vessel; removing residual dirt from the treatment vessel and melting the hydrates to facilitate release of clean water.

The present invention relates to systems and methods for manipulating droplets within a high through put microfluidic system.

A mixing system includes a container having a support plate and a mixing assembly supported on the support plate. The mixing assembly includes a pliable enclosure containing a fluid and a mixing device. A portion of the mixing device extends from the pliable enclosure and is adapted to be detachably coupled to a drive mechanism. A first plate is detachably secured to the rigid container. The pliable enclosure is disposed between the first plate and the support plate. A mixing arrangement includes a docking station having a drive cradle and a drive mechanism. The mixing system is removably positioned within the drive cradle so that the drive mechanism is removably coupled to the mixing device.

Method for handling at least one first microdrop and at least one second microdrop in a microfluidic system including a capillary trap that has a first trapping zone and a second trapping zone, the method including steps consisting of: (i) trapping the first microdrop in the first trapping zone, and (ii) trapping the second microdrop in the second trapping zone, the first and the second trapping zone being arranged such that the first and the second microdrops are in contact with each other, the first and the second trapping zones being adapted such that the trapping forces returned to one of the microdrops are different.

Apparatus that mixes non-homogenous fluid. A threaded shaft within a housing circulates fluid within a container to effect mixing. In one embodiment, when placed in a container of fluid, the housing the fluid is recirculated through opposing ends of the housing. In an embodiment of a related method for mixing, a pump housing containing a screw journaled for rotation receives fluid within a container and conveys the fluid therethrough to circulate a fluid portion in the container along an exterior surface of the housing for mixing with another fluid portion to improve fluid homogeneity. After mixing, the portion of the fluid which first circulates through the housing may recirculate through the housing with said another portion of the fluid. The fluid may be continuously mixed and recirculated through the housing.

Apparatus and methods for mixing and dispersing a dispersed phase in a medium comprise a rotating surface for receiving the medium and an atomizing apparatus positioned at the rotating surface for depositing aerosolized constituents of the dispersed phase into the medium. The medium is made receptive and the dispersed phase is aerosolized. Constituents of the aerosolized dispersed phase are deposited into the receptive medium to form a compound or composite. The medium may be deposited onto a rotating disk, and the dispersed phase may be sprayed onto the disk. A thin film can be generated on the disk to transfer, distribute, and disperse the dispersed phase. Liquid ligaments formed at the edge of the rotating disk further transfer, distribute, and disperse the dispersed phase into the medium. Ligaments may be broken into aerosols or deformed by attenuation/drawing to further promote transfer, distribution, and dispersion. A bulk composite/compound may be collected.

The present invention generally relates to microfluidics and/or epigenetic sequencing. In one set of embodiments, cells contained within a plurality of microfluidic droplets are lysed and the DNA (e.g., from nucleosomes) within the droplets are labeled, e.g., with adapters containing an identification sequence. The adapters may also contain other sequences, e.g., restriction sites, primer sites, etc., to assist with later analysis. After labeling with adapters, the DNA from the different cells may be combined and analyzed, e.g., to determine epigenetic information about the cells. For example, the DNA may be separated on the basis of certain modifications (e.g., methylation), and the DNA from the separated nucleosomes may be sequenced using techniques such as chromatin immunoprecipitation (“CUP”). In some cases, the DNA sequences may also be aligned with genomes, e.g., to determine which portions of the genome were epigenetically modified, e.g., via methylation.

An apparatus for mixing bone cement for use in orthopedic surgeries includes a mixing region and an agitator for mix the cement ingredients. A temperature sensing means of apparatus determines when that the cement mix can no longer be used. The apparatus can be operated or acted on by a power tool for the mixing of the bone cement. The power tool and/or mixing apparatus may include a mechanical torque limiter that inhibits the agitator as a result of mixing torque exceeding a threshold value. A timer of the apparatus may be started by a sensor of the apparatus or by the user in response to a mechanical torque value. When the timer is complete, a cue by the apparatus signals to the user that the mixed cement is ready and able to be applied.