Mixing devices and associated methods are described herein. Various embodiments of mixing devices can comprise a plate configured to rotate about a longitudinal axis and a plurality of enclosures coupled to the plate. The enclosures can each include (a) at least one sidewall that defines an oblique angle with the plate and (b) a chamber configured to receive a media and a fluid. The enclosures can be fluidly coupled to a fluid source for receiving the fluid in the chambers. When the plate is rotated, the enclosures revolve about the longitudinal axis to mix the media with the fluid in the chambers.

The systems and methods described herein assist a user in executing a recipe by recording and associating a blend sequence of blend steps with the recipe upon a first execution of the recipe. The systems and methods described herein further assist the user in modifying and executing the recorded blend sequence upon a second and subsequent execution of the recipe.

A beverage apparatus, the beverage apparatus being hand-holdable by a user of the beverage apparatus to be portable, can include a beverage chamber housing that includes a chamber for storing a consumable liquid. The beverage apparatus can include a dispensing assembly that includes a receptacle. The receptacle can retain a vessel. The vessel can include an electronic tag and can contain an additive. The dispensing assembly can be operatively controllable by a controller to output the additive from the vessel into the consumable liquid. The beverage apparatus can include one or more sensors, devices, or assemblies that can be used to detect a volume of liquid in the chamber or a liquid level in the chamber. The beverage apparatus can include an apparatus processing portion (ACP) and an apparatus database portion.

A dissolution generator apparatus includes: a dissolution generator, including: a housing shell; a powder support screen assembly extending across an interior of the housing shell and configured to support a column of powder; a pressure mechanism disposed adjacent the powder support screen assembly; a spray delivery assembly located adjacent the powder support screen assembly opposite to the pressure mechanism, the spray delivery assembly comprising a spray nozzle configured to spray a solvent through the powder support screen assembly; a duct having a first end in fluid communication with the housing shell, and a second end; a dissolved powder reservoir in fluid communication with the second end of the duct; and at least one recirculation pump disposed in fluid communication with both the dissolved powder reservoir and the spray delivery assembly, so as to form a fluid recirculation loop between the dissolved powder reservoir and the spray delivery assembly.

A method of determining a mixing state of a medium in a container includes: transmitting a plurality of acoustic signals at least partly through the medium and receiving the plurality of acoustic signals after at least partly traversing the medium; determining at least one propagation value of at least one propagation quantity for each of the plurality of received acoustic signals to provide determined propagation values, each at least one propagation quantity being indicative of an interaction of the acoustic signals with the medium; determining at least one fluctuation value of at least one fluctuation quantity based on the determined propagation values to provide a determined at least one fluctuation value, each at least one fluctuation quantity being indicative of and/or correlating with a variance of the determined propagation values and/or with a state of a mixture; and determining the mixing state of the medium.

The present disclosure relates to a combination including an outer container for mounting in a container holder of a planetary mixer, the outer container receiving an inner container arrangement allowing to mix ingredients into the inner container arrangement with the planetary mixer to produce in the inner container arrangement a pharmaceutical composition. The outer container may include a body having an outer wall and an inner wall. The inner wall may delimit a central cavity for nestably receiving the inner container arrangement. The outer container may also include a slot on the inner wall. The slot may engage with a protrusion on the inner container arrangement when the inner container arrangement is received in the central cavity to inhibit rotational motion of the inner container arrangement within the outer container, induced as a result of combined rotation and revolution imparted to the outer container by the planetary mixer.

A connecting chuck of a material cylinder for a mixer and a mixer are disclosed according to the present application. The chuck includes a chuck body, and a first axial position-limiting connector and a second axial position-limiting connector are provided on the chuck body. After the chuck body rotates around the outlet pipe of the material cylinder by a preset angle, the first axial position-limiting connector can cooperate with a first axial position-limiting cooperating member on the material cylinder, and the second axial position-limiting connector can cooperate with a second axial position-limiting cooperating member on the mixer, so that an inlet pipe of the mixer is compressed with the outlet pipe of the material cylinder for cooperation. Through the above structure, after use, the chuck body reversely rotates to an initial position and the mixer is replaced, and the chuck body is reusable without replacement.

Methods and related apparatus for providing a chemical intervention processing solution for use within processing tanks. Processing tanks can include side streams or ancillary systems for generating the chemical intervention processing solution that can then be introduced into the processing tanks. The antimicrobial agents will be added and mixed in the side stream to form the chemical intervention processing solution. Additional actions can be conducted on the processing solution within the side stream including any and or all of heating, pumping, sampling, measuring, testing and pH adjustment of the processing solution. The chemical intervention processing solution can also be provided by a venturi injector that combines processing water and an antimicrobial agent and/or an alkaline agent outside of the processing tank. The processing solution can be used for various food processing applications.

A mixing machine includes a head extending over a bowl receiving location, the head including a downwardly extending rotatable output shaft for receiving a mixer tool. A drive train including a motor having an output operatively connected to drive a planetary gear system that effects rotation of the rotatable output shaft about its axis and orbiting of the shaft axis about another axis. A control system includes a master control unit and a slave control unit, the master control unit connected with a first sensor located along the drive train between the motor and the planetary gear system, the slave control unit connected with a second sensor, wherein both the slave control unit and the second sensor rotate with a part of the planetary gear system, wherein the master control unit and the slave control unit are configured for wireless communication with each other.

A method of cell culture and a method of generating organoids is provided. The methods utilize a cell culture system which includes a multiwell culture plate having shafts for mixing culture media within wells of the culture plate. The multiwell culture plate includes a base substrate having a plurality of culture wells, and a shaft operably associated with each culture well, each shaft being configured to mix media present in each culture well and having a gear adapted to operably associate with a gear on a shaft associated with an adjacent culture well. The system further includes a motor having a drive shaft in operable communication with the shaft gears of the multiwell culture plate. The system can be widely used as a standard platform to generate stem cell-derived human organoids for any tissue and for high-throughput drug screenings, toxicity testing, and modeling normal human organ development and diseases.