A non-foil packaging laminate for liquid food packaging comprises a layer of paper or other cellulose-based material, outermost liquid tight, heat sealable layers of polyolefin-based polymers and, vapour-deposition coated onto the inner side of the layer of paper or cellulose-based material, an induction heat susceptible metal coating. Also disclosed is a method for manufacturing of the packaging laminate, a packaging container that is made from the packaging laminate and a method of induction heat sealing the packaging laminate into packaging containers.

A non-foil packaging laminate for liquid food packaging comprises a layer of paper or other cellulose-based material, outermost liquid tight, heat sealable layers of polyolefin-based polymers and, vapour-deposition coated onto the inner side of the layer of paper or cellulose-based material, an induction heat susceptible metal coating. Also disclosed is a method for manufacturing of the packaging laminate, a packaging container that is made from the packaging laminate and a method of induction heat sealing the packaging laminate into packaging containers.

A smoking device including a tubular element containing tobacco and a filtering element connected to an end of the tubular element. The filtering element includes at least one breakable flavouring capsule which includes at least one core having at least one lipophilic substance and at least one flavouring agent dispersed or dissolved in the lipophilic substance; at least one breakable coating which coats the core and which has at least one chitosan having a weight average molecular weight (Mw) between 25 kDa and 400 kDa. Preferably, the breakable coating further includes at least one polyhydroxyalkanoate (PHA). The frangible coating that coats the core is able to preserve its hardness, and therefore its breakability, during use by the smoker, i.e. in the presence of humidity and heat that develop from the combustion of tobacco.

A method of manufacturing a toy using a model frame in liquid includes: filling a water tank; dissolving calcium chloride, a powder component, into the water filled in the water tank; wherein the amount of calcium chloride is determined in anticipation of the degree of gelation by chemical action with sodium alginate, filling a liquid paint to the model frame; wherein the liquid paint is comprised water 96 wt. %, CNC 0.99 wt. %, sodium alginate 3 wt. %, luminous material 0.01 wt. % or water 91 wt. %, CNC 1 wt. %, sodium alginate 3 wt. %, shiny material 5 wt. % or water 96 wt. %, CNC 0.99 wt. %, sodium alginate 3 wt. %, color conversion material 0.01 wt. %; immersing the model frame filled with the liquid paint in the water tank; solidifying and shrinking the liquid paint filled in the model frame immersed in the water tank; and shaking the model frame.

The present disclosure discloses a xeno-free bio-ink formulation amenable to be printed using a 3D printer. The bio-ink formulation exhibits optimum viscosity in the range of 1690-5300 cP. The present disclosure discloses a bio-printed corneal lenticule obtained from the bio-ink formulation. The bio-printed corneal lenticule as disclosed is of the optimum thickness in the range of 10-500 microns and exhibits transmittance in the range of 80-99%. The present disclosure also discloses a process for preparing the bio-ink formulation as well as for preparing the bio-printed corneal lenticule. Further, the present disclosure discloses a method of treating a corneal defect using the bio-printed corneal lenticule as an implant to treat the corneal defect. The bio-printed corneal lenticule can further be used as a model for in-vitro drug testing and diseases modelling.

The present disclosure discloses embodiments of a formulation for application to the cornea, the formulation comprising a hyaluronic acid, a gelatin, and exosomes. In certain variations, the exosomes may be naive mesenchymal stem cell-derived exosomes, primed mesenchymal stem cell derived-exosomes, or corneal stromal stem cell derived-exosomes. In certain variations, the primed mesenchymal stem cell-derived exosomes are exosomes derived from mesenchymal stem cells primed with a corneal stromal stem cell derived-conditioned medium.

A method of making a dispenser includes: mixing a plurality of materials, the materials including plant fiber, vegetable gum, starch, a toughening agent, and a dispersing agent; utilizing a granulator to form the mixture of the plant fiber, the vegetable gum, the starch, the toughening agent, and the dispersing agent into pellets; and forming a dispenser by moving the pellets into a processing machine; wherein the processing machine melts the pellets and disposes the melted material into a cavity configured as a forming mold, and after cooling the dispenser is obtained.

Multi component fibres for the reduction of the damaging activity of wound exudate components such as protein degrading enzymes and inflammatory mediators in wounds, the fibres comprising: from 10% to 100% by weight of the fibres of pectin and a sacrificial proteinaceous material in a weight ratio of 100:0 to 10:90 pectin to sacrificial proteinaceous material and from 0% to 90% by weight of the fibres of another polysaccharide or a water soluble polymer.

An injection molding apparatus and method of fabricating a molded part are provided. The apparatus may include a barrel, a nozzle enclosing an end of the barrel and defining an opening in fluid communication with an inside of the barrel, and an extrusion screw positioned at least partially inside the barrel and rotatable relative to the barrel. The extrusion screw may include a screw tip. Relative axial movement between the barrel and the extrusion screw may open or close the opening of the nozzle to permit or prevent, respectively, material flow through the opening of the nozzle. The method may include clamping a mold, opening a nozzle, rotating the extrusion screw to pump a molten material into the mold until the mold is filled, closing the nozzle, and unclamping the mold to release a molded part.

The present invention relates to a microstructure including a biocompatible polymer or an adhesive and to a method for manufacturing the same. The present inventors optimized the aspect ratio according to the type of each microstructure, thereby ensuring the optimal tip angle and the diameter range for skin penetration. Especially, the B-type to D-type microstructures of the present invention minimize the penetration resistance due to skin elasticity at the time of skin attachment, thereby increasing the penetration rate of the structures (60% or higher) and the absorption rate of useful ingredients into the skin. In addition, the D-type microstructure of the present invention maximizes the mechanical strength of the structure by applying a triple structure, and thus can easily penetrate the skin. When the plurality of microstructures are arranged in a hexagonal arrangement type, a uniform pressure can be transmitted to the whole microstructures on the skin.