A vacuum storage system (40) for storing an article, comprises a sealable outer chamber (30) and a sealable inner chamber (20). The sealable outer chamber (30) has an evacuation valve (21) for connection to a suction device (48) for evacuation of said outer chamber (30). The sealable inner chamber (20) is adapted to receive said article and has a one-way valve (13) in communication with the outer chamber (30). The one-way valve (13) is adapted to open upon the application of suction to the outer chamber (30), thereby to enable evacuation of said inner chamber (20), but to close upon discontinuation of said suction.

Compositions of and methods for formulating and delivering biologically active agent formulations having enhanced physical stability, and wherein deterioration from the presence of oxygen and/or water is minimized and/or controlled, to yield a stable formulation. The compositions of and methods for formulating and delivering biologically active agents of the present invention further facilitate their incorporation into a biocompatible coating which can be employed to coat a stratum-corneum piercing microprojection, or a plurality of stratum-corneum piercing microprojections of a delivery device, for delivery of the biocompatible coating through the skin of a subject, thus providing an effective means of delivering the biologically active agents.

Compositions of and methods for formulating and delivering biologically active agent formulations having enhanced physical stability, and wherein deterioration from the presence of oxygen and/or water is minimized and/or controlled, to yield a stable formulation. The compositions of and methods for formulating and delivering biologically active agents of the present invention further facilitate their incorporation into a biocompatible coating which can be employed to coat a stratum-corneum piercing microprojection, or a plurality of stratum-corneum piercing microprojections of a delivery device, for delivery of the biocompatible coating through the skin of a subject, thus providing an effective means of delivering the biologically active agents.

This disclosure relates to equipment utilized to manufacture chemical agents, particularly biopharmaceuticals, using Disposable Containers (DCs).

This disclosure relates to equipment utilized to manufacture chemical agents, particularly biopharmaceuticals, using Disposable Containers (DCs).

A method for producing a container having an upper part, a lower part and a receiving element such as an electronics module includes the following steps: the lower part is created from a first starting material in a first processing region of a processing device; the upper part is created from a second starting material in a second processing region of the processing device; the receiving element is fed into the first processing region of the processing device; the lower part receives the receiving element in the first processing region of the processing device; the upper part is fed from the second processing region into the first processing region of the processing device; and there the upper part and the lower part are joined together to form the container.

A method for producing a container having an upper part, a lower part and a receiving element such as an electronics module includes the following steps: the lower part is created from a first starting material in a first processing region of a processing device; the upper part is created from a second starting material in a second processing region of the processing device; the receiving element is fed into the first processing region of the processing device; the lower part receives the receiving element in the first processing region of the processing device; the upper part is fed from the second processing region into the first processing region of the processing device; and there the upper part and the lower part are joined together to form the container.

A fluid distribution system is configured to distribute fluid from a first vessel to second vessels includes a hub assembly and a frame assembly. The hub assembly has an input cap, a distribution cap, a first clamp, and a second clamp. The input cap defines an inlet and the distribution cap is sealingly secured to the input cap with a plenum being defined between the input and distribution caps. The distribution cap includes conduit connectors that each defines an outlet in fluid communication with the plenum. The first clamp is disposed over the distribution cap and is engaged with the input cap to secure the input cap to the distribution cap and the second clamp is disposed over the input cap and engaged with the distribution cap to secure the distribution cap to the input cap. The frame assembly supports the hub assembly and is configured to secure each of the secondary vessels at a predetermined distance relative to the hub assembly.

Method and apparatus are disclosed for capping a plurality of bottles enclosed and sealed in a plastic bag. The method comprises disposing the plurality of bottles in a tray in a predetermined array such that caps, disposed in a plate can be displaced for convenient capping in a single step. Ratchet tools are disclosed for facile threading of caps to bottles.

Method and apparatus are disclosed for capping a plurality of bottles enclosed and sealed in a plastic bag. The method comprises disposing the plurality of bottles in a tray in a predetermined array such that caps, disposed in a plate can be displaced for convenient capping in a single step. Ratchet tools are disclosed for facile threading of caps to bottles.