A self-sterilizing display device is applied to self-sterilizing with a UV light. The self-sterilizing display device includes a display, a light-incident layer, a light source, and a turning layer. The light-incident layer is disposed above the display. The light source is disposed at a periphery of the light-incident layer, and a light-emitting surface of the light source faces to the light-incident layer. The turning layer is disposed on a lower surface of the light-incident layer. Herein, the light source can emit the UV light toward the light-incident layer for sterilizing an outer surface of the self-sterilizing display device by irradiation, and the turning layer can change the direction of an optical path of the UV light. Therefore, the surface can be sterilized by UV light, and the UV light can be prevented or reduced from being incident on the display below and damaging the display.