This disclosure relates to the field of molecules having pesticidal utility against pests in Phyla Arthropoda, Mollusca, and Nematoda, processes to produce such molecules, intermediates used in such processes, pesticidal compositions containing such molecules, and processes of using such pesticidal compositions against such pests. These pesticidal compositions may be used, for example, as acaricides, insecticides, miticides, molluscicides, and nematicides. This document discloses molecules having the following formula (“Formula One”). ##STR00001##

This disclosure relates to the field of molecules having pesticidal utility against pests in Phyla Arthropoda, Mollusca, and Nematoda, processes to produce such molecules, intermediates used in such processes, pesticidal compositions containing such molecules, and processes of using such pesticidal compositions against such pests. These pesticidal compositions may be used, for example, as acaricides, insecticides, miticides, molluscicides, and nematicides. This document discloses molecules having the following formula (“Formula One”). ##STR00001##

The present invention provides a production method capable of efficiently synthesizing an SF.sub.5 group-containing compound, or the like. The present invention is a method for synthesizing an SF.sub.5 group-containing compound represented by the general formula (1) from a thioaryl compound represented by the general formula (2) [A.sup.1 is an aryl group or a heteroaryl group; G.sup.1 is SH, SCN, SF.sub.3, SSR.sup.1, SCOR.sup.2, SR.sup.3, SF.sub.2R.sup.4, SSi(R.sup.5).sub.3, SPO(R.sup.6).sub.2, (N-phthalimidyl)thio group, or a thianthrenium group (R.sup.1 is an aryl group or a heteroaryl group; R.sup.2 and R.sup.5 are an aryl group, a heteroaryl group, an alkyl group, or an alkenyl group; R.sup.3 and R.sup.4 are an alkyl group or an alkenyl group, R.sup.6 is an aryloxy group, a heteroaryloxy group, an alkyloxy group, or an alkenyloxy group)].

[Chemical Formula 1]

A.sup.1G.sup.1(2)

A.sup.1SF.sub.5(1)

The present invention provides compounds according to Formula I as described herein, and their use for inhibiting the lysine gingipain protease (Kgp) from the bacterium Porphyromonas gingivalis. Also described are gingipain activity probe compounds and methods for assaying gingipain activity are also described, as well as methods for the treatment of disorders associated with P. gingivalis infection, including brain disorders such as Alzheimer's disease.

The present invention provides compounds according to Formula I as described herein, and their use for inhibiting the lysine gingipain protease (Kgp) from the bacterium Porphyromonas gingivalis. Also described are gingipain activity probe compounds and methods for assaying gingipain activity are also described, as well as methods for the treatment of disorders associated with P. gingivalis infection, including brain disorders such as Alzheimer's disease.

An organic sulfur material comprising carbon, hydrogen, oxygen, and sulfur as constituent elements, and having peaks in the vicinity of 482 cm1, 846 cm1, 1066 cm1, 1279 cm1, and 1442 cm1 in a Raman spectrum detected by Raman spectroscopy, the peak in the vicinity of 1442 cm1 being most intense, has a high capacity and high heat resistance, although a liquid organic starting material is used.

An organic sulfur material comprising carbon, hydrogen, oxygen, and sulfur as constituent elements, and having peaks in the vicinity of 482 cm1, 846 cm1, 1066 cm1, 1279 cm1, and 1442 cm1 in a Raman spectrum detected by Raman spectroscopy, the peak in the vicinity of 1442 cm1 being most intense, has a high capacity and high heat resistance, although a liquid organic starting material is used.

Provided herein are compounds, compositions, and methods useful for modulating the integrated stress response (ISR) and for treating related diseases; disorders and conditions.

Disclosed herein are compounds of formula ArN(SO.sub.2F).sub.2, wherein Ar is selected from an optionally substituted aryl, an optionally substituted five-membered heteroaryl, or an optionally substituted six-membered heteroaryl. Also disclosed are methods of synthesizing the above compounds by reacting a compound of formula ArNHR.sub.9 with MN(SO.sub.2F).sub.2. ##STR00001##

Disclosed herein are compounds of formula ArN(SO.sub.2F).sub.2, wherein Ar is selected from an optionally substituted aryl, an optionally substituted five-membered heteroaryl, or an optionally substituted six-membered heteroaryl. Also disclosed are methods of synthesizing the above compounds by reacting a compound of formula ArNHR.sub.9 with MN(SO.sub.2F).sub.2. ##STR00001##