Novel compositions and systems for closure of wounds with antimicrobial effectiveness are disclosed. The compositions provide devices of improved flexibility and elasticity and are readily applied to wound sites or over wound closure devices. The present invention is also directed to a novel platinum catalyst for use in such compositions. The catalyst provides for rapid curing on topical surfaces such as skin and bonds to such surfaces in about 2-5 minutes.

This disclosure describes compositions including a perfluoropolyether (PFPE) bottlebrush polymer, optionally blended with other fluoropolymers. The compositions may be disposed on an article, including, for example, a porous filtration media, to form a fluoropolymer-containing article. This disclosure further describes methods of making fluoropolymer-containing articles and methods of using the fluoropolymer-containing articles.