COVID-19 is a large virus with remarkable resilience, propagation and multiplication features that require complex technologic systems and manners to assure a reasonable protection. A transparent, multiuse face mask with valves and for inhalation of air from a specialized filter placed in a cleaner air space, and an exhalation valve that drives the exhaled air via a tube to a filter bladder placed on wrist and from there to a tube that has the release end near ground, or can be connected to the aspiration tube of the infrastructure, that removes it, preventing recirculation. The general convention that defines the usage method is that the building, buss, and any other enclosure provide clean antiseptic air above and consumer s have to release their exhalations down near floor from where the structure to remove them by a controlled air flow similar to clean rooms.

The main condition is that people to place their exhalation exhaust sterilized and placed near ground in order to increase the probability to inhale clean sterile air at the head level. No filter is perfect, and no sterilization unit, therefore the enclosure has to deal with exhaust gas, and remove into the atmosphere safely. The work to keep people inside safe is done by both the enclosure that may provide vacuum lines to collect the exhaled air, and by the people who will use correctly the infrastructure. The system is designed for smart communities for everybody to wear for about 3 weeks when a covid-19 or other virus infection occurs to suppress its multiplication rate, without perturbation in their activity and then returning to normality.

Provided herein are isolation processes and the associated hardware to allow fluid streams to be isolated from a sterilized system (e.g., a sterile process vessel) that contains a sterile process. The isolation processes described herein allow for continuous removal of fluid streams (e.g., waste streams, liquid containing recombinant therapeutic proteins) from a sterilized system (e.g., a biological manufacturing system), which provides for less manual manipulation of the sterilized system and a decreased risk of contaminating the sterilized system.

A vessel having a mixer that ensures a homogeneous cell distribution in dispensed quantities. The vessel has a mixer therein for stirring contents of the vessel and an orifice in a lower wall to which a cell dispenser is attached. The cell dispenser dispenses quantities of suspended cells having a homogeneous cell distribution. The vessel may be a closed system with no option or instructions for removing a cap or other access port, whereby after manufacturing the vessel is shipped to a customer and the interior remains closed to the exterior environment and fluids are transferred through tubes.

A bag assembly for use with a heat exchanger includes a flexible bag having of one or more sheets of polymeric material, the bag having a first end that bounds a first compartment and an opposing second end that bounds a second compartment, a support structure being disposed between the first compartment and the second compartment so that the first compartment is separated and isolated from the second compartment. A first inlet port, a first outlet port, and a first drain port are coupled with the flexible bag so as to communicate with the first compartment. A second inlet port, a second outlet port, and a second drain port are coupled with the flexible bag so as to communicate with the second compartment.

The invention refers to a plant for treating receptacles adapted to contain a pourable product comprising: at least a treatment unit apt to carry out a treatment process on the receptacles; an isolation chamber housing the treatment unit and containing, in use, a controlled atmosphere controlled in sterile and/or aseptic conditions; and a filtering unit configured to filter a gas to be introduced in the isolation chamber for constituting the controlled atmosphere; wherein the treatment plant further comprises a test device housed inside the isolation chamber, immersed, in use, in the controlled atmosphere and configured to perform one or more test operations on the filtering unit.

The purpose of the present invention is to provide a clean air device that can reduce the risk of contamination due to static electricity. Provided is a biosafety cabinet or a clean air device that connects a biosafety cabinet and a clean booth, wherein a static eliminator (ionizer) that generates a corona discharge by way of concentrating an electric field on a needle-shaped discharge electrode and eliminates static with ionized air is disposed directly above an air flow branching point where air supplied to a work space branches to the front face and to rear face inside the biosafety cabinet.

An object of the present invention is to provide a safety cabinet capable of controlling the purity during usage. In order to realize the object, the safety cabinet is configured to include an operation space including an operation stage; a front panel formed in a front surface of the operation space; an operation opening provided in a lower portion of the front panel; a suction port that is provided in the vicinity of the operation opening on a front side of the operation stage to lead downward; an air circulation path through which air suctioned from the suction port flows along a lower portion, a back surface, and an upper portion of the operation space; a particle counter; an operation space-air intake port provided in the operation space to take air into the particle counter; and an introduction pipe that introduces the air into the particle counter from the operation space-air intake port.

Manufacturing system and method for creating multiple tissue constructs from cells. System can include a thaw subsystem (if the cells are provided in a frozen state), an expansion subsystem, a concentration subsystem, and a tissue maturation subsystem. Each of these subsystems is modular and can be reconfigured, and the process can be repeated depending on the specific tissue process being implemented. Multiple tissue types can be combined in multiple bioreactors. The activities of multiple bioreactors can be coordinated and controlled in an automated manner by a supervisor controller. The supervisor controller can receive user input at the start of the process, and can manage the process henceforth, alerting the user if user actions are required.

Apparatus and methods for monitoring embryos in an incubator are described. The apparatus comprises an incubation chamber defined by an incubation chamber housing and a slide carrier comprising a plurality of compartment walls that define compartments for holding embryo slides within the incubation chamber for incubation. The slide carrier is moveable, for example by rotation, relative to the incubation chamber housing to allow a selected compartment to be moved to a loading position defined at least in part by a loading port wall associated with the incubation chamber housing. The loading port wall is arranged to cooperate with the wall of a compartment in the loading position to restrict the extent to which the environment of the compartment in the loading position is in fluid communication with the environments of other compartments in the incubation chamber.

A closed fluid receiving and sampling container that enables transfer of valuable reaction liquid to a receptacle without risking loss of sterility. The sampling container has a dip tube subassembly with a shorter inlet tube bent towards the wall of the receptacle to prevent or reduce foaming, and a longer outlet tube used to drain the waste liquid once the magnetic beads are trapped by the magnet. The dip tube subassembly is injection molded in one piece and provides a sealed lid also with a vent tube therethrough to enable filling and draining the receptacle without removing the lid, thus keeping the process aseptic. The sampling container is especially useful in the context of magnetic bead separation processes.