Various embodiments of the present technology provide methods and systems for soil enrichment. The systems may comprise a bioreactor system coupled to an initial treatment system for the cultivation of a live microorganism culture containing organic nutrients on an agriculturally effective scale. The systems may be automated and/or portable for practical applications onto target fields. The live microorganism culture may be delivered onto the soil of the target fields, enriching the soil with the organic nutrients that become bioavailable to crops growing in the soil. The soil enrichment system may provide a sustainable approach to agriculture that may efficiently enhance the natural processes of the native soil of any crop.

A culturing device includes a microplate including a plurality of vessels, each of the vessels having a bottom surface having light transmittance and an opening at an upper portion, a lid having light transmittance, and an intermediate plate having light transmittance sandwiched between the lid and the microplate. The intermediate plate has a plurality of convex portions on a surface thereof facing the microplate and provided with a plurality of through holes corresponding to the convex portions that are disposed so that when the intermediate plate and the microplate are overlapped, each of the plurality of convex portions is inserted into each of the plurality of vessels and each of the plurality of through holes coincides with the opening of each of the plurality of vessels. The lid comes into contact with the intermediate plate so as to close the plurality of through holes provided in the intermediate plate.

The present invention relates to a bacteriostatic filter system for an antibody drug production process, and to a method of operating same, in which devices are configured and the system is designed so as to enable, through a control unit, the in-lining of a bacteriostatic filter cartridge and in-situ integrity testing of a bacteriostatic filter, wherein according to a result value of the integrity testing, media or buffer are transferred to a storage tank from a preparation tank, or the media or buffer transferred to the storage tank are transferred back to the preparation tank. Accordingly, the present invention can reduce the time required for filter cartridge replacement and integrity testing and implement a system having automated the transferring and backfeeding of media and buffers as well as processing liquids, and can thus reduce the amount of labor needed and shorten the processing time.

A culturing assistance device includes an image acquisition unit configured to acquire a captured image of cells during culturing at determined times, a storage control unit configured to store the captured image acquired by the image acquisition unit and event information indicating an event related to culturing of the cells, and a learning unit configured to learn a relationship between the stored captured image and the stored event information.

This disclosure relates to equipment utilized to manufacture chemical agents, particularly biopharmaceuticals, using Disposable Containers (DCs).

A method is provided for vaporized hydrogen peroxide cleaning of a chamber. The method includes altering a temperature of air in the chamber from an initial temperature to a sterilization temperature over a first time period. The method also includes injecting vaporized hydrogen peroxide into air in the chamber to alter a relative humidity of hydrogen peroxide vapor in the chamber to a sterilization level over the first time period. The method also includes maintaining the temperature at the sterilization temperature and the relative humidity at the sterilization level over a second time period. The method also includes reducing the relative humidity from the sterilization level to a safe level over a third time period. In one embodiment, the method is provided for vaporized hydrogen peroxide cleaning of an interior chamber of an incubation container. In other embodiments, the incubation chamber featured in the method is provided.

The invention provides a resin molding and a method of producing the same in which sterilizability thereof is secured and discoloration (yellowing) thereof is reduced even when the resin molding is radiation-irradiated under anaerobic conditions (deoxidation conditions). The radiation-irradiated and packaged resin molding is primarily packaged with a packaging material having oxygen permeability and then secondarily packaged with an oxygen impermeable packaging material together with a deoxidizer. The method of producing a radiation-irradiated and packaged resin molding involves a step of primarily packaging a resin molding before radiation irradiation with a packaging material having oxygen permeability, a step of subsequently secondarily packaging with an oxygen impermeable packaging material together with a deoxidizer, and then a step of conducting radiation irradiation. A step of opening the secondary packaging under the atmosphere, following the radiation irradiation step, is preferred.

A bioprocessing system comprising a series of processing stations for performing operations for bioprocessing is disclosed. The bioprocessing system includes an automated system comprising means for manipulating a fluid connection between a first container and a separable second container whereby to create an aseptic connection that enables a controlled transfer of fluid or cell material between the first container and the second container, wherein the means for manipulating a fluid connection is configured to create an aseptic connection that can be disconnected after the transfer of fluid or cell material is complete to enable a further such fluid connection to be manipulated between the first container and a separable third container, and means for controlling an automated sequence of operation of the processing stations.

A product and method for sampling cells from a bioreactor, for the purposes of determine the cell count or to remove a sample and retain sterility of the sample for quality control (OC) assessment. More specifically, a product and a method for sampling of cells during a cell expansion in a bioreactor using vacuum tubes.

A cell culture apparatus is provided which can continuously and accurately measure turbidity of a cell culture solution and culture a cell, without inserting a turbidity sensor from outside into a sterile bag. The cell culture apparatus includes: a flexible and transparent sterile bag that is installed at a prescribed position in the cell culture apparatus and in which a cell contained in a cell culture solution is cultured; and a turbidity sensor that includes a light emitter which emits light to the cell culture solution in the sterile bag via a portion of the sterile bag, a light receiver which receives the light transmitted through the cell culture solution via another portion of the sterile bag, and that is configured to place the light emitter, the portion of the sterile bag, another portion of the sterile bag, and the light receiver, optically on a same straight line.