Patent classifications
C12N2533/00
NEURAL CELL POPULATION, NEURAL CELL-CONTAINING PREPARATION, AND METHOD FOR PRODUCING SAID POPULATION AND PREPARATION
The present disclosure relates to a neural cell population, a neural cell-containing preparation, and a method for producing the population and preparation. More particularly, the present invention relates to a neural cell population derived from intraoral mesenchymal cells, wherein a proportion of normal diploid cells is 80% or more, a preparation containing the neural cell population, and a method for producing the population and the preparation.
PROTEIN-MODIFIED PLGA MICROSPHERE AND TISSUE-ENGINEERED NERVE CONSTRUCTED THEREWITH
A protein-modified PLGA microsphere can be used to construct tissue-engineered nerve. The microspheres are loaded with active substances for treating peripheral nerve injury and are bound to tissue-engineered nerves. It has been shown that the prepared tissue-engineered nerve effectively promotes nerve regeneration after peripheral nerve injury.
Cell culture substratum, method for producing cell-containing material, method for producing cell culture substratum, method for observing cells, and cell culture substratum maintenance fluid
The purpose of the present invention is to provide a cell culture substratum which has excellent resistance to liquid culture media and low cytotoxicity, can achieve a high cell adhesion ratio and a high viability of cultured cells, has excellent thermal stability, and is less likely to absorbs ultraviolet ray. A cell culture substratum which is provided with a substrate made from an inorganic material and has multiple concavo-convex structures on a culturing surface thereof, wherein, when the concavo-convex structures are measured with an atomic force microscope in accordance with JISB0601 and JISR1683 (measured area: a 1 μm-square, cut-off value of a low-pass contour curve filter: 1 nm, cut-off value of a high-pass contour curve filter: 170 nm), the average of the lengths of contour curve elements of the concavo-convex structures is 1 to 170 nm as measured in at least one direction (when a curve showing long-wavelength components that are blocked by the high-pass contour curve filter is converted to a straight line by the least square method, the average line is a line that is parallel with the straight line and indicates a height cumulative relative frequency distribution in the contour curve of 50%).
NANOCOIL-SUBSTRATE COMPLEX FOR CONTROLLING STEM CELL BEHAVIOR, PREPARATION METHOD THEREOF, AND METHOD OF CONTROLLING ADHESION AND DIFFERENTIATION OF STEM CELL BY USING THE SAME
The present invention relates to a nanocoil-substrate complex for controlling adhesion and differentiation of stem cells, a manufacturing method thereof, and a method of controlling adhesion and differentiation of stem cells by using the nanocoil-substrate complex, and the method of controlling adhesion and differentiation of stem cells may temporally and reversibly control adhesion and phenotypic differentiation of stem cells in vivo and ex vivo by controlling application/non-application of a magnetic field to the nanocoil-substrate complex.
System and method for creating tissue
- Christopher C. Langenfeld ,
- David D. B. Cannan ,
- Dirk A. van der Merwe ,
- Dean Kamen ,
- Jason A. Demers ,
- Frederick Morgan ,
- Timothy D. Moreau ,
- Brian D. Tracey ,
- Matthew Ware ,
- Richard J. Lanigan ,
- Michael A. Baker ,
- David Blumberg, Jr. ,
- Richard E. Gautney ,
- Derek G. Kane ,
- Dane Fawkes ,
- Thomas J. Bollenbach ,
- Michael C. Tilley ,
- Stuart A. JACOBSON ,
- John F. Mannisto
A system and method for growing and maintaining biological material including producing a protein associated with the tissue, selecting cells associated with the tissue, expanding the cells, creating at least one tissue bio-ink including the expanded cells, printing the at least one tissue bio-ink in at least one tissue growth medium mixture, growing the tissue from the printed at least one tissue bio-ink, and maintaining viability of the tissue.
TISSUE SCAFFOLDS AND CONSTRUCTS
An electrostimulatable 3-dimensional (3D) electrogel scaffold comprising piezoelectric nanoparticles uniformly dispersed throughout a homogenous hydrogel polymer matrix, wherein the hydrogel polymer matrix is gelled and comprises crosslinked alginate, carboxymethyl-chitosan and agarose polymers.
System and Method for Creating Tissue
- Christopher C. Langenfeld ,
- David D. B. Cannan ,
- Dirk A. van der Merwe ,
- Dean Kamen ,
- Jason A. Demers ,
- Frederick Morgan ,
- Timothy D. Moreau ,
- Brian D. Tracey ,
- Matthew Ware ,
- Richard J. Lanigan ,
- Michael A. Baker ,
- David Blumberg, Jr. ,
- Richard E. Gautney ,
- Derek G. Kane ,
- Dane Fawkes ,
- Thomas J. Bollenbach ,
- Michael C. TILLEY ,
- Stuart A. JACOBSON ,
- John F. Mannisto
A system and method for growing and maintaining biological material including producing a protein associated with the tissue, selecting cells associated with the tissue, expanding the cells, creating at least one tissue bio-ink including the expanded cells, printing the at least one tissue bio-ink in at least one tissue growth medium mixture, growing the tissue from the printed at least one tissue bio-ink, and maintaining viability of the tissue.
Proton conductive two-dimensional amorphous carbon film for gas membrane and fuel cell applications
Described is a fuel cell comprising an electrode catalyst assembly, and a two-dimensional (2D) amorphous carbon, wherein the 2D amorphous carbon has a crystallinity (C)≤0.8.
Live cell constructs for production of cultured milk product and methods using the same
This invention relates to live cell constructs for in vitro and/or ex vivo production of cultured milk products from mammary cells, methods of producing isolated cultured milk products from mammary cells, bioreactors for producing isolated cultured milk products, and cultured milk products.
CELL CULTURE METHOD AND AUTOMATIC CELL CULTURE APPARATUS
A novel cell culture method for inducing differentiation of a pluripotent stem cell into trophoblast and an automatic culture apparatus therefor includes: a first step of culturing the pluripotent stem cell in a presence of a ROCK inhibitor during a first time period; a second step of culturing the pluripotent stem cell, which has been subjected to the first step, without the ROCK inhibitor during a second time period following the first time period; and a step of culturing the pluripotent stem cell, which has been subjected to the second step, in the presence of the ROCK inhibitor during a third time period following the second time period, in which the pluripotent stem cell is cultured in a state of being adhered to a cell culture substrate including a planar mesh through the first to third time periods.