A system and process for bioleaching target metals from sulfide mineral ores and concentrates uses organisms that are genetically modified to produce excessive amounts of amino acids and related compounds, where the organisms are supplied within leach solutions to leach pads comprised of sulfide mineral ores or to leach solutions in CSTRs.

The present disclosure relates to a method for efficiently producing lactic acid by fermenting brewers' spent grains. The method specifically includes the following steps: (1) adding water to brewers' spent grains after alkali pretreatment so as to adjust a solid content of a fermentation production system to 10%-15%, adding cellulase to the brewers' spent grains according to an addition amount of 5 FPU/g-10 FPU/g, carrying out hydrolysis at 50 C.-60 C. and pH of 4.5-5.2 for 20 hours-48 hours, and obtaining a prehydrolyzed substrate; and (2) inoculating hydrolysate prepared in step (1) with a lactic acid bacteria seed solution with a viable count of 110.sup.8 CFU/mL-110.sup.10 CFU/mL according to an inoculation amount of 10%-15% (v/v), conducting fermentation at 40 C.-55 C. and pH of 6.0-7.2 for 72 hours-96 hours, and obtaining a fermentation broth.

Provided are a recombinant expression vector for whooping cough antigens, an engineered bacterium and use thereof. The recombinant expression vector for whooping cough antigens comprises a protein expression cassette for pertactin, a gene for resistance screening, and an upstream recombinant nucleic acid fragment and a downstream recombinant nucleic acid fragment of filamentous haemagglutinin gene, wherein the protein expression cassette for pertactin is located between the upstream recombinant nucleic acid fragment and the downstream recombinant nucleic acid fragment of the filamentous haemagglutinin gene, and the upstream recombinant nucleic acid fragment and the downstream recombinant nucleic acid fragment of the filamentous haemagglutinin gene can undergo homologous recombination with the upstream and downstream of the filamentous haemagglutinin gene, respectively. The gene of FHA protein in the recombinant expression vector is knocked out and the copies PRN protein gene are increased, so that the Bordetella pertussis genetically engineered strain can efficiently overexpress PRN protein antigen and PT protein, and the expressed PRN protein antigen and PT protein exist in the cells and the supernatant respectively, thereby facilitating subsequent separation and purification of the antigens.

New Lactococcus lactis strains, NRRL B-50571 and NRRL B-50572, and a bacterial preparation containing the same, have the ability to produce bioactive peptides that reduce blood pressure, lower LDL-cholesterol (bad cholesterol) and present antioxidant properties for better cardiovascular health. These biologically active peptides may be produced within the food for the production of a food product, such as a functional food, or they may be produced from protein sources and subsequently added to a food as part of the formulation or as part of a food supplement or a pharmaceutical preparation.

New Lactococcus lactis strains, NRRL B-50571 and NRRL B-50572, and a bacterial preparation containing the same, have the ability to produce bioactive peptides that reduce blood pressure, lower LDL-cholesterol (bad cholesterol) and present antioxidant properties for better cardiovascular health. These biologically active peptides may be produced within the food for the production of a food product, such as a functional food, or they may be produced from protein sources and subsequently added to a food as part of the formulation or as part of a food supplement or a pharmaceutical preparation.

The present invention relates to a novel hyperhalophilic strain and use thereof for the degradation of carbon-containing substrates, in particular making it possible to prepare novel polymers.

The invention relates to a bacterial strain belonging to the genus Rhodococcus which is a producer of a nitrile hydratase. The invention also relates to a method for producing acrylamide by hydration of acrylonitrile using a biomass of the bacterial strain and to a method of culturing the bacterial strain.

New Lactococcus lactis strains, NRRL B-50571 and NRRL B-50572, and a bacterial preparation containing the same, have the ability to produce bioactive peptides that reduce blood pressure, lower LDL-cholesterol (bad cholesterol) and present antioxidant properties for better cardiovascular health. These biologically active peptides may be produced within the food for the production of a food product, such as a functional food, or they may be produced from protein sources and subsequently added to a food as part of the formulation or as part of a food supplement or a pharmaceutical preparation.

New Lactococcus lactis strains, NRRL B-50571 and NRRL B-50572, and a bacterial preparation containing the same, have the ability to produce bioactive peptides that reduce blood pressure, lower LDL-cholesterol (bad cholesterol) and present antioxidant properties for better cardiovascular health. These biologically active peptides may be produced within the food for the production of a food product, such as a functional food, or they may be produced from protein sources and subsequently added to a food as part of the formulation or as part of a food supplement or a pharmaceutical preparation.

The present invention relates to means and methods comprising Paraburkholderia bacteria for use in preventing and/or controlling plant pests, in particular Erwinia amylovora which constitutes the causative agent of fire blight. The present invention thus relates to novel non-medical uses of Paraburkholderia bacteria for preventing and/or controlling pests on a plant and/or on a temporary part of a plant and/or being located inside of a plant. Furthermore, the present invention relates to methods and compositions comprising Paraburkholderia bacteria for preventing and/or controlling such pests on a plant and/or on a temporary part of a plant and/or being located inside of a plant as well as to the use of Paraburkholderia bacteria for the preparation of such compositions. Further provided are kits comprising components used in the methods and compositions of the invention. The inventive use of Paraburkholderia bacteria for the prevention and/or control of plant pests are, without being limiting, particularly useful in commercial crop protection campaigns, particularly against the causative agent of fire blight. Erwinia amylovora.