A staple cartridge assembly for use with a surgical stapling instrument includes a staple cartridge including a plurality of staples and a cartridge deck. The staple cartridge assembly also includes a compressible adjunct positionable against the cartridge deck, wherein the staples are deployable into tissue captured against the compressible adjunct, and wherein the compressible adjunct comprises a first biocompatible layer comprising a first portion, a second biocompatible layer comprising a second portion, and crossed spacer fibers extending between the first portion and the second portion.

A heart valve assembly, a prosthetic valve device, and a preparation method for a heart valve assembly. The heart valve assembly comprises: a skirt portion having a tubular structure, at least two leaflets provided on an inner wall of the skirt portion, a plurality of integrated anchoring rings provided on the exterior of the skirt portion; one end of the integrated anchoring ring is fixedly provided to the exterior of the skirt portion, and one end thereof is a free end; and the skirt portion, the leaflets and the integrated anchoring rings form an integrated valve structure. The heart valve component simplifies an assembly process by significantly reducing the need for precise sutures for connecting the valve component(s) to a stent, which can reduce the uncertainty of current suture technology.

Methods of culturing and manufacturing of cells on a large-scale level are disclosed. Particularly, a manufacturing system and device, and methods of using the system and device for culturing and manufacturing cells in hollow fibers made from alginate polymers are provided.

Underwear or undergarment, particularly for a female wearer. A seamless knitted-yarn tubular blank is produced and is rotated; a front-side partial-cut is introduced, and a rear-side partial-cut is introduced; thereby forming two leg openings and one waist opening. Optionally, an elastic-free lace band is seamlessly glued or bonded or attached to the region that borders the waist opening. The underwear can be manufactured from a single, seamless, tubular knitted-yarn blank, without leaving or removing or discarding any fabric residues.

A staple cartridge assembly for use with a surgical stapling instrument includes a staple cartridge including a plurality of staples and a cartridge deck. The staple cartridge assembly also includes a compressible adjunct positionable against the cartridge deck, wherein the staples are deployable into tissue captured against the compressible adjunct, and wherein the compressible adjunct comprises a first biocompatible layer comprising a first portion, a second biocompatible layer comprising a second portion, and crossed spacer fibers extending between the first portion and the second portion.

Disclosed are a highly absorbent composite fiber, a highly absorbent non-woven fabric, and an article including the non-woven fabric. The disclosed highly absorbent composite fiber includes: a core including a polyolefin-based resin; and a sheath including ethylene vinyl alcohol (EVOH) resin.

Thermally stable absorbable fiber populations, i.e. fiber populations that do not undergo thermally induced crystallization, can be intermixed with thermally unstable fibers to yield a stabilizing effect without altering morphological properties of a fiber system. Via this, one may minimize thermally induced shrinkage and maintain physical properties of electrospun materials in the as-formed state.

Embodiments of the present disclosure provide a medical product with a biodegradable portion. The biodegradable portion is made of a biodegradable material and the biodegradable portion degrades faster than the remaining portion of the medical product.

The present invention relates to a process for the surface treatment of poly(aryl ether ketone)s (PAEKs) comprising the following steps: Providing an article comprising one or more poly(aryl ether ketone)s (PAEKs); contacting at least one portion of the surface of the article containing one or more poly(aryl ether ketone)s (PAEKs) with an aldehyde,
wherein the aldehyde reacts with the poly(aryl ether ketone)(s) (PAEKs) on the at least one portion of the surface of the article to form a hydroxyalkyl and/or hydroxyaryl group,
a process for functionalizing surface-treated poly(aryl ether ketone)s (PAEKs) comprising the steps of: a) Treating at least one portion of the surface of an article containing one or more poly(aryl ether ketone)s (PAEKs) with the surface treatment process for poly(aryl ether ketone)s (PAEKs) described herein; b) Coating the treated at least one portion of the surface of the article with a composition comprising a chemical compound having chemical groups capable of forming a covalent bond with hydroxyalkyl and/or hydroxyaryl groups formed on the surface of the article,
an article comprising one or more poly(aryl ether ketone)s (PAEKs) and a coating on at least one surface of the article, wherein on the coated at least one portion of the surface of the article the poly(aryl ether ketone)(s) (PAEKs) contains hydroxyalkyl and/or hydroxyaryl groups; and at least one portion of the hydroxyalkyl and/or hydroxyaryl groups of the poly(aryl ether ketone)(s) (PAEKs) has formed covalent bonds with chemical groups of at least one chemical compound in the coating, and
the use of the article of the invention as described herein as a medical device and/or biotechnological applications, preferably as an implant, scaffold structure for in vitro applications and/or scaffold structure for cell culture applications.

The invention provides devices for supporting regeneration of body tissue and of tubular structures, such as the esophagus or intestine, and methods for making and for using the devices.