A channel-less microfluidic pump includes a cartridge including a substrate and an actuatable film layer disposed on the substrate, and a manifold having at least three actuatable void volumes separated by a plurality of wall sections and an actuatable flexible layer disposed on the manifold interfacing the actuatable film layer. In operation, the pump can be in an unactuated state wherein the actuatable film layer is disposed against the surface of the substrate or an actuated state wherein at least a portion of the flexible layer and a corresponding portion of the actuatable film layer are deflected into a corresponding void volume thus forming a fluidic volume between the deflected portion of the actuatable film layer and the surface of the substrate. In the actuated state, there is a fluidic gap between immediately adjacent void volumes formed by a thinned region of the flexible layer at a point of contact with a top surface of a wall section. A method of transporting fluid using the channel-less microfluidic pump is described.

A peristaltic pump (10) comprises a drivable rotor (14), having at least one pressing member (15), and a cylindrical stator (12) in which the rotor (14) is rotatable. Flexible tubing (22), having an inlet side (24) and an outlet side (26), extends circumferentially around the cylindrical stator (12) against an inner wall (12a). The peristaltic pump (10) includes a radially deformable ring (28) positioned between the rotor (14) and the circumferentially extending flexible tubing (22). The ring (28) is deformed by the pressing member (15) upon rotation of the rotor (14) and this compresses the flexible tubing (22) against the inner wall (12a) of the cylindrical stator (12) to convey liquid along the flexible tubing (22). The radially deformable ring (28) includes a ring anchor (30) which prevents rotation of the radially deformable ring (28) during rotation of the rotor (14).

A fluororubber tube is provided, which is formed from a rubber composition containing a fluororubber, and not less than 3.8 parts by mass and not greater than 4.1 parts by mass of a polyol crosslinking agent and not less than 3 parts by mass and not greater than 7 parts by mass of a carbon black based on 100 parts by mass of the fluororubber. Thus, the fluororubber tube is made less tacky by suppressing the intrinsic adhesiveness of the crosslinked fluororubber without formation of a coating film which may otherwise complicate the structure of the tube and the production process of the tube or may result in contamination.

The present specification describes a modular, portable hemofiltration system, for providing improved clearance levels of blood toxins, which includes at least one roller pump that is designed and operated to generate a rapidly varying pressure profile of fluid within at least a blood circuit of the hemofiltration system.

A device for dispensing a liquid may include a basin defining a reservoir, a pump including a barrel and a spring, the barrel coupled to the basin, the barrel defining a cavity, and the spring disposed in the cavity, and an actuator at least partially disposed in the reservoir, the actuator defining a first orifice, a second orifice, and a lumen extending between the first orifice and the second orifice, the reservoir in fluid communication with the lumen via the first orifice, the actuator depressible to move the second orifice in a first direction defined from the reservoir toward the cavity of the barrel, and the spring of the pump biasing the actuator to move in a second direction defined from the cavity of the barrel toward the reservoir.

A peristaltic pump apparatus for a medical device has a housing, a motor, a first peristaltic pump head, a second peristaltic pump head, a first clutch assembly, and a second clutch assembly. The motor is directly connected to the housing and has a rotatable drive shaft. Each of the first peristaltic pump head and the second peristaltic pump head is coupled to the rotatable drive shaft. The first clutch assembly has a first rotor fixedly connected to the rotatable drive shaft and a first stator directly connected to the housing. The first clutch assembly is configured to selectively electromagnetically couple the first rotor to the first peristaltic pump head. The second clutch assembly has a second rotor fixedly connected to the rotatable drive shaft and a second stator directly connected to the housing. The second clutch assembly selectively electromagnetically couples the second rotor to the second peristaltic pump head.

A wastewater sump assembly for receiving and disposing of undesired fluid and, in some cases, solid waste (collectively “wastewater”). A sump basin includes an upstanding wall a base and a top. A sensor in the form, e.g., of a float switch extends into the basin and is operable to actuate a pump to remove collective wastewater from the basin. The sensor depends from a sensor support that is supported distally within the basin in a vertical manner and is supported proximately within the basin in a horizontal manner, with securement of the sensor support not requiring traversal of the basin top and with the distal basin support not needing to be accessed vertically through a pump access aperture in the top.

A positive displacement pump includes a housing surrounding a drive chamber and a diaphragm compartment. A drive element is inside the drive chamber. A diaphragm is inside the diaphragm compartment and divides the diaphragm compartment into a fluid chamber and a cavity. A shaft connects the drive element and the diaphragm. A breather valve is fluidically connected to the cavity and is configured to allow air to exit the cavity. The cavity is fluidically disconnected from the drive chamber.

A diagnostic test assembly, including: a substrate having formed therein a plurality of mutually spaced open reservoirs and fluidic channels; a deformable membrane attached to the substrate to cover the open reservoirs and fluidic channels; a rigid covering disposed over the deformable membrane, the rigid covering being configured to allow respective actuators external to the diagnostic test assembly to displace corresponding portions of the deformable membrane; wherein at least some of the portions of the deformable membrane act as pumping portions, each pumping portion being disposed over a corresponding one of the reservoirs and being configured so that when it is displaced by a corresponding actuator, it is displaced into the corresponding reservoir to pump fluid from the corresponding reservoir through at least a corresponding one of the fluidic channels; and wherein one or more of the portions of the deformable membrane act as valve portions, each valve portion being configured so that when it is displaced, it blocks fluid flow through a corresponding reservoir or fluidic channel; and wherein movement of fluid within the diagnostic test assembly can be controlled by controlling displacements of the portions of the deformable membrane.

A diagnostic test assembly, including: a substrate having formed therein a plurality of mutually spaced open reservoirs and fluidic channels; a deformable membrane attached to the substrate to cover the open reservoirs and fluidic channels; a rigid covering disposed over the deformable membrane, the rigid covering being configured to allow respective actuators external to the diagnostic test assembly to displace corresponding portions of the deformable membrane; wherein at least some of the portions of the deformable membrane act as pumping portions, each pumping portion being disposed over a corresponding one of the reservoirs and being configured so that when it is displaced by a corresponding actuator, it is displaced into the corresponding reservoir to pump fluid from the corresponding reservoir through at least a corresponding one of the fluidic channels; and wherein one or more of the portions of the deformable membrane act as valve portions, each valve portion being configured so that when it is displaced, it blocks fluid flow through a corresponding reservoir or fluidic channel; and wherein movement of fluid within the diagnostic test assembly can be controlled by controlling displacements of the portions of the deformable membrane.