Provided in the disclosure relates to a panel of gene expression markers for cancer patient treated or to be treated by karenitecin. The disclosure provides methods and compositions, e.g., kits, for evaluating gene expression levels of the markers and methods of using such gene expression levels to predict a cancer patient's response to karenitecin. Such information can be used in determining prognosis and treatment options for cancer patients.

To provide a method whereby viscoelasticity of an object can be measured nondestructively and in non-contact fashion in a short time. By this method, elastic waves and light are radiated to an object and the viscoelasticity of an object is measured nondestructively and in non-contact fashion using a shadow change based on a change in the direction of a line normal to the surface of the object. Specifically, the present invention has an elastic wave transmission step for pressurizing or exciting the object by elastic waves and causing a minute displacement of the object surface shape, a photoirradiation step for radiating light to the minutely displaced object surface, an image acquisition step for acquiring a shadow change based on a change in the direction of a line normal to the object surface, and a viscoelasticity estimation step for processing an image of the acquired shadow change and calculating a viscoelasticity.

An apparatus for mass spectrometry and/or ion mobility spectrometry is disclosed comprising a first device arranged and adapted to generate aerosol, smoke or vapor from a target and one or more second devices arranged and adapted to aspirate aerosol, smoke, vapor and/or liquid to or towards an analyzer. A liquid trap or separator is provided to capture and/or discard liquid aspirated by the one or more second devices.

An apparatus for mass spectrometry and/or ion mobility spectrometry is disclosed comprising a first device arranged and adapted to generate aerosol, smoke or vapor from a target and one or more second devices arranged and adapted to aspirate aerosol, smoke, vapor and/or liquid to or towards an analyzer. A liquid trap or separator is provided to capture and/or discard liquid aspirated by the one or more second devices.

A central member defines a sample chamber and includes an elastic material configured to enclose at least a portion of a sample, acoustic sensors configured to detect sound waves in the sample chamber, and acoustic emitters configured to emit sounds waves in the central member. A pressure-retaining case is configured to contain a pressurized fluid between an annulus formed between the pressure-retaining case and the central member. A switch is configured to connect or disconnect a pulser and receiver circuit to a specified emitter of the acoustic emitters. A data acquisition unit is configured to receive a signal from each of the acoustic sensors. A pulser and receiver circuit is configured to send an electric pulse to an acoustic emitter and a control signal to the data acquisition unit.

A central member defines a sample chamber and includes an elastic material configured to enclose at least a portion of a sample, acoustic sensors configured to detect sound waves in the sample chamber, and acoustic emitters configured to emit sounds waves in the central member. A pressure-retaining case is configured to contain a pressurized fluid between an annulus formed between the pressure-retaining case and the central member. A switch is configured to connect or disconnect a pulser and receiver circuit to a specified emitter of the acoustic emitters. A data acquisition unit is configured to receive a signal from each of the acoustic sensors. A pulser and receiver circuit is configured to send an electric pulse to an acoustic emitter and a control signal to the data acquisition unit.

A method for material lifetime evaluation includes: causing a stress to be applied to a material surface of a component based at least on a cycle of load properties over time; causing an image of the material surface to be captured as a captured image of a complete in-situ field; determining an area of a hysteresis of a stable surface strain region in a stress-strain curve of the material surface to determine a loss energy (first damage parameter) for low cycle fatigue modeling; determining a deformation energy (second damage parameter) for high cycle fatigue monitoring; determining a failure parameter based on at least one of the first damage parameter and the second damage parameter; comparing the failure parameter to a record in a database; and determining a remaining life of the component based on comparison of the failure parameter to the record in the database.

The present invention relates to polypropylene non-woven fabric having excellent loft property, a method for preparing polypropylene non-woven fabric having excellent loft property, and a method for evaluating the properties of the polypropylene resin.

Analysis of residual stress in materials is often done in static conditions in a laboratory. Accurate systems and methods for performing these analyses in a dynamic, non-laboratory environment are notoriously difficult and can be very inaccurate. A method using a portable, field deployable apparatus having greater accuracy than currently available is disclosed whereby accurate and repeatable residual stress analysis may be implemented in non-laboratory environments leading to greatly improved diagnostics, maintenance and life limit prediction.

Analysis of residual stress in materials is often done in static conditions in a laboratory. Accurate systems and methods for performing these analyses in a dynamic, non-laboratory environment are notoriously difficult and can be very inaccurate. A method using a portable, field deployable apparatus having greater accuracy than currently available is disclosed whereby accurate and repeatable residual stress analysis may be implemented in non-laboratory environments leading to greatly improved diagnostics, maintenance and life limit prediction.